Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 11152
• Symbol: WDR45
• Description: WD repeat domain 45

DataSource: http://genomecrispr.dkfz.de/#!/results/WDR45

Export (tab separated) Export to Excel

Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
49075353	49075376	X	+	26472758	Jiyoye	viability	GGGGTACTCACGCGGAGCGGCGG	WDR45	ENSG00000196998	-0.4047522703415548	[78]	[44]	-3	hSpCas9	negative selection	181220
49077733	49077756	X	-	26472758	Jiyoye	viability	CTGTCCAGACCACGAGCAGGTGG	WDR45	ENSG00000196998	0.1875335711854602	[261]	[224]	1	hSpCas9	negative selection	181221
49078061	49078084	X	+	26472758	Jiyoye	viability	AGGCTGGTCACTCCTCGAAGTGG	WDR45	ENSG00000196998	-1.2773227927661974	[44]	[13]	-7	hSpCas9	negative selection	181222
49075907	49075930	X	+	26472758	Jiyoye	viability	GCAGTTGCTTCTCCAGGCTGGGG	WDR45	ENSG00000196998	0.8983158598705088	[179]	[252]	6	hSpCas9	negative selection	181223
49075569	49075592	X	-	26472758	Jiyoye	viability	AAACTGGTGGAGCTGCGCCGAGG	WDR45	ENSG00000196998	2.7291034763932354	[0]	[4]	9	hSpCas9	negative selection	181224
49076430	49076453	X	-	26472758	Jiyoye	viability	TGATACCCGGGACAACCCCAAGG	WDR45	ENSG00000196998	-0.028923733300799892	[22]	[16]	0	hSpCas9	negative selection	181225
49075619	49075642	X	+	26472758	Jiyoye	viability	AATAAGGGTACCCTTCTGGGAGG	WDR45	ENSG00000196998	0.46214184072380193	[102]	[106]	3	hSpCas9	negative selection	181226
49077718	49077741	X	-	26472758	Jiyoye	viability	GCAGGTGGGCAGCATGGGCTTGG	WDR45	ENSG00000196998	0.1491942033983651	[170]	[142]	1	hSpCas9	negative selection	181227
49076654	49076677	X	+	26472758	Jiyoye	viability	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	-0.19273746068125436	[96]	[63]	-1	hSpCas9	negative selection	181228
49076460	49076483	X	+	26472758	Jiyoye	viability	ACAGCTTTCGGGGATTGTCGGGG	WDR45	ENSG00000196998	0.4802388436955968	[76]	[80]	3	hSpCas9	negative selection	181229
49075353	49075376	X	+	26472758	KBM7	viability	GGGGTACTCACGCGGAGCGGCGG	WDR45	ENSG00000196998	0.5364880595652151	[436,203]	[182,236]	6	hSpCas9	negative selection	372338
49077733	49077756	X	-	26472758	KBM7	viability	CTGTCCAGACCACGAGCAGGTGG	WDR45	ENSG00000196998	0.5379603995410055	[808,920]	[553,635]	6	hSpCas9	negative selection	372339
49078061	49078084	X	+	26472758	KBM7	viability	AGGCTGGTCACTCCTCGAAGTGG	WDR45	ENSG00000196998	-0.10900269067619006	[210,122]	[57,82]	-1	hSpCas9	negative selection	372340
49075907	49075930	X	+	26472758	KBM7	viability	GCAGTTGCTTCTCCAGGCTGGGG	WDR45	ENSG00000196998	0.11464921991106958	[1359,1023]	[694,516]	1	hSpCas9	negative selection	372341
49075569	49075592	X	-	26472758	KBM7	viability	AAACTGGTGGAGCTGCGCCGAGG	WDR45	ENSG00000196998	0.9361817869961198	[81,42]	[12,91]	8	hSpCas9	negative selection	372342
49076430	49076453	X	-	26472758	KBM7	viability	TGATACCCGGGACAACCCCAAGG	WDR45	ENSG00000196998	0.5035772770914373	[115,47]	[59,45]	5	hSpCas9	negative selection	372343
49075619	49075642	X	+	26472758	KBM7	viability	AATAAGGGTACCCTTCTGGGAGG	WDR45	ENSG00000196998	0.19460144339043695	[471,244]	[232,146]	2	hSpCas9	negative selection	372344
49077718	49077741	X	-	26472758	KBM7	viability	GCAGGTGGGCAGCATGGGCTTGG	WDR45	ENSG00000196998	-0.08126632406838485	[991,790]	[429,360]	-1	hSpCas9	negative selection	372345
49076654	49076677	X	+	26472758	KBM7	viability	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	-0.22657961706460428	[246,355]	[161,89]	-2	hSpCas9	negative selection	372346
49076460	49076483	X	+	26472758	KBM7	viability	ACAGCTTTCGGGGATTGTCGGGG	WDR45	ENSG00000196998	0.34991632369845344	[555,480]	[216,392]	4	hSpCas9	negative selection	372347
49075353	49075376	X	+	26472758	Raji	viability	GGGGTACTCACGCGGAGCGGCGG	WDR45	ENSG00000196998	1.2142987392901115	[129]	[69]	9	hSpCas9	negative selection	563456
49077733	49077756	X	-	26472758	Raji	viability	CTGTCCAGACCACGAGCAGGTGG	WDR45	ENSG00000196998	0.34792330342030686	[473]	[139]	3	hSpCas9	negative selection	563457
49078061	49078084	X	+	26472758	Raji	viability	AGGCTGGTCACTCCTCGAAGTGG	WDR45	ENSG00000196998	0.2708822676564787	[99]	[27]	2	hSpCas9	negative selection	563458
49075907	49075930	X	+	26472758	Raji	viability	GCAGTTGCTTCTCCAGGCTGGGG	WDR45	ENSG00000196998	0.8282551534195048	[630]	[259]	7	hSpCas9	negative selection	563459
49075569	49075592	X	-	26472758	Raji	viability	AAACTGGTGGAGCTGCGCCGAGG	WDR45	ENSG00000196998	0.20691920892451376	[55]	[14]	2	hSpCas9	negative selection	563460
49076430	49076453	X	-	26472758	Raji	viability	TGATACCCGGGACAACCCCAAGG	WDR45	ENSG00000196998	0.30002861331599573	[76]	[21]	3	hSpCas9	negative selection	563461
49075619	49075642	X	+	26472758	Raji	viability	AATAAGGGTACCCTTCTGGGAGG	WDR45	ENSG00000196998	-0.46145929998427987	[355]	[59]	-4	hSpCas9	negative selection	563462
49077718	49077741	X	-	26472758	Raji	viability	GCAGGTGGGCAGCATGGGCTTGG	WDR45	ENSG00000196998	-0.5775598464443245	[462]	[71]	-4	hSpCas9	negative selection	563463
49076654	49076677	X	+	26472758	Raji	viability	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	-0.6612909185199447	[183]	[26]	-5	hSpCas9	negative selection	563464
49076460	49076483	X	+	26472758	Raji	viability	ACAGCTTTCGGGGATTGTCGGGG	WDR45	ENSG00000196998	0.813820331739599	[276]	[112]	7	hSpCas9	negative selection	563465
49075353	49075376	X	+	26472758	K562	viability	GGGGTACTCACGCGGAGCGGCGG	WDR45	ENSG00000196998	1.8070762929568787	[238]	[705]	9	hSpCas9	negative selection	754574
49077733	49077756	X	-	26472758	K562	viability	CTGTCCAGACCACGAGCAGGTGG	WDR45	ENSG00000196998	0.6828253808887323	[841]	[1140]	5	hSpCas9	negative selection	754575
49078061	49078084	X	+	26472758	K562	viability	AGGCTGGTCACTCCTCGAAGTGG	WDR45	ENSG00000196998	-3.3670159844159007	[219]	[17]	-8	hSpCas9	negative selection	754576
49075907	49075930	X	+	26472758	K562	viability	GCAGTTGCTTCTCCAGGCTGGGG	WDR45	ENSG00000196998	1.1568537667883254	[882]	[1661]	8	hSpCas9	negative selection	754577
49075569	49075592	X	-	26472758	K562	viability	AAACTGGTGGAGCTGCGCCGAGG	WDR45	ENSG00000196998	-0.698997743967186	[74]	[38]	-4	hSpCas9	negative selection	754578
49076430	49076453	X	-	26472758	K562	viability	TGATACCCGGGACAACCCCAAGG	WDR45	ENSG00000196998	0.9073837403888763	[95]	[151]	7	hSpCas9	negative selection	754579
49075619	49075642	X	+	26472758	K562	viability	AATAAGGGTACCCTTCTGGGAGG	WDR45	ENSG00000196998	1.1799868550714485	[434]	[831]	8	hSpCas9	negative selection	754580
49077718	49077741	X	-	26472758	K562	viability	GCAGGTGGGCAGCATGGGCTTGG	WDR45	ENSG00000196998	-0.06745903768586814	[750]	[604]	0	hSpCas9	negative selection	754581
49076654	49076677	X	+	26472758	K562	viability	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	0.3583096941944312	[279]	[302]	3	hSpCas9	negative selection	754582
49076460	49076483	X	+	26472758	K562	viability	ACAGCTTTCGGGGATTGTCGGGG	WDR45	ENSG00000196998	1.1052254412727034	[298]	[542]	8	hSpCas9	negative selection	754583
49077736	49077759	X	-	26627737	DLD1	viability	TCCCTGTCCAGACCACGAGCAGG	WDR45	ENSG00000196998	-0.35922709267597985	[736]	[214,257,83]	-4	hSpCas9	negative selection	845899
49077736	49077759	X	-	26627737	GBM cells	viability after 5 days	TCCCTGTCCAGACCACGAGCAGG	WDR45	ENSG00000196998	-0.37473420497296006	[381]	[144,170]	-5	hSpCas9	negative selection	928214
49077736	49077759	X	-	26627737	GBM cells	viability after 13 days	TCCCTGTCCAGACCACGAGCAGG	WDR45	ENSG00000196998	-0.11917485166121555	[381]	[197,184]	-1	hSpCas9	negative selection	1010529
49077736	49077759	X	-	26627737	GBM cells	viability after 21 days	TCCCTGTCCAGACCACGAGCAGG	WDR45	ENSG00000196998	-0.541477773199063	[381]	[163,122]	-5	hSpCas9	negative selection	1092844
49077736	49077759	X	-	26627737	RPE1	viability after 9 days	TCCCTGTCCAGACCACGAGCAGG	WDR45	ENSG00000196998	1.8975000984339014	[316]	[274,491]	8	hSpCas9	negative selection	1175159
49077736	49077759	X	-	26627737	RPE1	viability after 12 days	TCCCTGTCCAGACCACGAGCAGG	WDR45	ENSG00000196998	1.6238674779348714	[316]	[176,352]	8	hSpCas9	negative selection	1257474
49077736	49077759	X	-	26627737	RPE1	viability after 15 days	TCCCTGTCCAGACCACGAGCAGG	WDR45	ENSG00000196998	1.3954580557156882	[316]	[156,311]	7	hSpCas9	negative selection	1339789
49077736	49077759	X	-	26627737	RPE1	viability after 18 days	TCCCTGTCCAGACCACGAGCAGG	WDR45	ENSG00000196998	2.0654696525208545	[316]	[272,448]	8	hSpCas9	negative selection	1422104
49077736	49077759	X	-	26627737	HeLa	viability after 8 days	TCCCTGTCCAGACCACGAGCAGG	WDR45	ENSG00000196998	-0.05357682300321459	[446]	[269,101,206]	0	hSpCas9	negative selection	1504419
49077736	49077759	X	-	26627737	HeLa	viability after 12 days	TCCCTGTCCAGACCACGAGCAGG	WDR45	ENSG00000196998	0.5613817190485009	[446]	[261,248,308]	5	hSpCas9	negative selection	1586734
49077736	49077759	X	-	26627737	HeLa	viability after 15 days	TCCCTGTCCAGACCACGAGCAGG	WDR45	ENSG00000196998	-0.04490225675573631	[446]	[175,142,212]	0	hSpCas9	negative selection	1669049
49077736	49077759	X	-	26627737	HeLa	viability after 18 days	TCCCTGTCCAGACCACGAGCAGG	WDR45	ENSG00000196998	-0.006796667504243237	[446]	[129,114,212]	0	hSpCas9	negative selection	1751364
49077736	49077759	X	-	26627737	HCT116	viability after 6 days	TCCCTGTCCAGACCACGAGCAGG	WDR45	ENSG00000196998	0.8728621492409068	[372]	[69,127]	5	hSpCas9	negative selection	1833679
49077736	49077759	X	-	26627737	HCT116	viability after 8 days	TCCCTGTCCAGACCACGAGCAGG	WDR45	ENSG00000196998	0.3467473768584231	[367]	[198,351,221]	4	hSpCas9	negative selection	1915994
49077736	49077759	X	-	26627737	HCT116	viability after 9 days	TCCCTGTCCAGACCACGAGCAGG	WDR45	ENSG00000196998	1.8119059598686351	[372]	[447,271]	9	hSpCas9	negative selection	1998309
49077736	49077759	X	-	26627737	HCT116	viability after 12 days	TCCCTGTCCAGACCACGAGCAGG	WDR45	ENSG00000196998	-0.20869257935019697	[367]	[133,250,121]	-2	hSpCas9	negative selection	2080624
49077736	49077759	X	-	26627737	HCT116	viability after 15 days	TCCCTGTCCAGACCACGAGCAGG	WDR45	ENSG00000196998	0.10790619102482268	[367]	[352,241,104]	1	hSpCas9	negative selection	2162939
49077736	49077759	X	-	26627737	HCT116	viability after 18 days	TCCCTGTCCAGACCACGAGCAGG	WDR45	ENSG00000196998	0.15781389878144692	[367]	[110,297,178]	1	hSpCas9	negative selection	2245254
49077641	49077664	X	+	24336569	HL60	viability	ACCTGAGATCTCTGAGAACTTGG	WDR45	ENSG00000196998	0.12114444476264152	[964]	[2220]	1	hSpCas9	negative selection	2306288
49077677	49077700	X	+	24336569	HL60	viability	GCCCACCAAGGCCAGAAGGTTGG	WDR45	ENSG00000196998	0.05270113769581619	[117]	[258]	0	hSpCas9	negative selection	2306289
49077682	49077705	X	+	24336569	HL60	viability	CCAAGGCCAGAAGGTTGGAGCGG	WDR45	ENSG00000196998	-0.12937408559028163	[994]	[1924]	-1	hSpCas9	negative selection	2306290
49077715	49077738	X	-	24336569	HL60	viability	GGTGGGCAGCATGGGCTTGGTGG	WDR45	ENSG00000196998	0.35737642323515395	[1622]	[4399]	3	hSpCas9	negative selection	2306291
49077723	49077746	X	-	24336569	HL60	viability	CACGAGCAGGTGGGCAGCATGGG	WDR45	ENSG00000196998	0.06223458042775898	[844]	[1866]	0	hSpCas9	negative selection	2306292
49077729	49077752	X	+	24336569	HL60	viability	CTGCCCACCTGCTCGTGGTCTGG	WDR45	ENSG00000196998	-0.6571933215720156	[622]	[835]	-5	hSpCas9	negative selection	2306293
49077736	49077759	X	-	24336569	HL60	viability	TCCCTGTCCAGACCACGAGCAGG	WDR45	ENSG00000196998	2.9185358993711037	[40]	[655]	9	hSpCas9	negative selection	2306294
49078029	49078052	X	+	24336569	HL60	viability	ATCCTCTCTCACTTTGGTCTTGG	WDR45	ENSG00000196998	1.4118046013136458	[248]	[1401]	8	hSpCas9	negative selection	2306295
49078061	49078084	X	+	24336569	HL60	viability	AGGCTGGTCACTCCTCGAAGTGG	WDR45	ENSG00000196998	0.33278568635034067	[686]	[1830]	3	hSpCas9	negative selection	2306296
49078073	49078096	X	-	24336569	HL60	viability	ATGACTCAACAGCCACTTCGAGG	WDR45	ENSG00000196998	0.7373864602665372	[374]	[1322]	6	hSpCas9	negative selection	2306297
49077641	49077664	X	+	24336569	KBM7	viability	ACCTGAGATCTCTGAGAACTTGG	WDR45	ENSG00000196998	0.7345596148694861	[757]	[3439]	6	hSpCas9	negative selection	2373465
49077677	49077700	X	+	24336569	KBM7	viability	GCCCACCAAGGCCAGAAGGTTGG	WDR45	ENSG00000196998	-0.8168130062146014	[216]	[335]	-6	hSpCas9	negative selection	2373466
49077682	49077705	X	+	24336569	KBM7	viability	CCAAGGCCAGAAGGTTGGAGCGG	WDR45	ENSG00000196998	-0.006347200459248192	[920]	[2500]	0	hSpCas9	negative selection	2373467
49077715	49077738	X	-	24336569	KBM7	viability	GGTGGGCAGCATGGGCTTGGTGG	WDR45	ENSG00000196998	-0.4301159619059125	[1436]	[2908]	-4	hSpCas9	negative selection	2373468
49077723	49077746	X	-	24336569	KBM7	viability	CACGAGCAGGTGGGCAGCATGGG	WDR45	ENSG00000196998	1.2738578014585473	[424]	[2802]	9	hSpCas9	negative selection	2373469
49077729	49077752	X	+	24336569	KBM7	viability	CTGCCCACCTGCTCGTGGTCTGG	WDR45	ENSG00000196998	1.4211504040660452	[331]	[2424]	9	hSpCas9	negative selection	2373470
49077736	49077759	X	-	24336569	KBM7	viability	TCCCTGTCCAGACCACGAGCAGG	WDR45	ENSG00000196998	0.9727526023994744	[84]	[454]	8	hSpCas9	negative selection	2373471
49078029	49078052	X	+	24336569	KBM7	viability	ATCCTCTCTCACTTTGGTCTTGG	WDR45	ENSG00000196998	1.1752325653250812	[394]	[2432]	8	hSpCas9	negative selection	2373472
49078061	49078084	X	+	24336569	KBM7	viability	AGGCTGGTCACTCCTCGAAGTGG	WDR45	ENSG00000196998	-0.5553031993882674	[548]	[1018]	-4	hSpCas9	negative selection	2373473
49078073	49078096	X	-	24336569	KBM7	viability	ATGACTCAACAGCCACTTCGAGG	WDR45	ENSG00000196998	0.47602233926756343	[411]	[1562]	4	hSpCas9	negative selection	2373474
49097851	49097874	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTTCACCATGTTGGTCAGGCCGG	WDR45	ENSG00000196998	-0.9950505910624323	[34,30]	[4,1]	-6	dCas9-VP64	positive selection	2385333
49092049	49092072	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGGCGGAGGTTGCAGTGAGCGAG	WDR45	ENSG00000196998	-1.3881494200540772	[95,289]	[14,16]	-7	dCas9-VP64	positive selection	2387286
49080079	49080102	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTCAAGGCCGAGACTGTCTGAGG	WDR45	ENSG00000196998	-0.2908386266292753	[49,307]	[39,23]	-1	dCas9-VP64	positive selection	2390651
49080005	49080028	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	GACAGTGGGGTTCTCCGGGGAGG	WDR45	ENSG00000196998	1.7828249232806717	[0,4]	[0,3]	6	dCas9-VP64	positive selection	2390652
49079980	49080003	X	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCGCGATGCTCCGAAGACCCGGG	WDR45	ENSG00000196998	-0.4494870969929493	[92,55]	[7,14]	-2	dCas9-VP64	positive selection	2390653
49088312	49088335	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGAGAATCGCTTGAATCCTGG	WDR45	ENSG00000196998	1.579452491414227	[20,39]	[3,36]	6	dCas9-VP64	positive selection	2477212
49097851	49097874	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTTCACCATGTTGGTCAGGCCGG	WDR45	ENSG00000196998	-0.9351084987288634	[176,47]	[27,9]	-8	dCas9-VP64	positive selection	2480588
49092049	49092072	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGGCGGAGGTTGCAGTGAGCGAG	WDR45	ENSG00000196998	-0.15452703381003985	[117,34]	[33,11]	-1	dCas9-VP64	positive selection	2482541
49080079	49080102	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTCAAGGCCGAGACTGTCTGAGG	WDR45	ENSG00000196998	0.27919117618154976	[326,363]	[131,140]	2	dCas9-VP64	positive selection	2485906
49080005	49080028	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	GACAGTGGGGTTCTCCGGGGAGG	WDR45	ENSG00000196998	-1.1529645729112477	[134,36]	[21,2]	-9	dCas9-VP64	positive selection	2485907
49079980	49080003	X	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCGCGATGCTCCGAAGACCCGGG	WDR45	ENSG00000196998	-0.3456744485985146	[111,235]	[40,46]	-3	dCas9-VP64	positive selection	2485908
49088312	49088335	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGAGAATCGCTTGAATCCTGG	WDR45	ENSG00000196998	0.3334805796334224	[96,125]	[24,64]	2	dCas9-VP64	positive selection	2572467
49076461	49076484	X	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACAGCTTTCGGGGATTGTCGGGG	WDR45	ENSG00000196998	-0.44149348253472037	[2,2]	[2,0]	-6	hSpCas9	positive selection	3032316
49077683	49077706	X	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCAAGGCCAGAAGGTTGGAGCGG	WDR45	ENSG00000196998	0.5237525585228426	[2,2]	[2,3]	9	hSpCas9	positive selection	3032317
49076429	49076452	X	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GATACCCGGGACAACCCCAAGGG	WDR45	ENSG00000196998	-0.04131133549470595	[3,3]	[4,1]	0	hSpCas9	positive selection	3032318
49076482	49076505	X	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGAAGGAGTACACATAGATGCGG	WDR45	ENSG00000196998	0.3623078210475335	[4,4]	[3,6]	7	hSpCas9	positive selection	3032319
49076461	49076484	X	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACAGCTTTCGGGGATTGTCGGGG	WDR45	ENSG00000196998	0.12832680573506544	[2,2]	[3,1]	2	hSpCas9	positive selection	3100174
49077683	49077706	X	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCAAGGCCAGAAGGTTGGAGCGG	WDR45	ENSG00000196998	0.3536491980404393	[2,2]	[3,1]	6	hSpCas9	positive selection	3100175
49076429	49076452	X	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GATACCCGGGACAACCCCAAGGG	WDR45	ENSG00000196998	-0.6445973517474355	[3,3]	[0,1]	-8	hSpCas9	positive selection	3100176
49076482	49076505	X	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGAAGGAGTACACATAGATGCGG	WDR45	ENSG00000196998	-0.4508979564769926	[4,4]	[3,1]	-6	hSpCas9	positive selection	3100177
49077891	49077914		-	24336571	A375	resistance to PLX after 7 days	AGGCTGCTTTTGCTGCGCCATGG	WDR45	ENSG00000196998	0.0928714531584437	[19,13]	[16,19]	3	hSpCas9	positive selection	3155480
49076740	49076763		-	24336571	A375	resistance to PLX after 7 days	CCTGCCCAGCAGTGCTGATCTGG	WDR45	ENSG00000196998	-0.0883802139504255	[41,39]	[39,36]	-3	hSpCas9	positive selection	3155481
49076654	49076677		+	24336571	A375	resistance to PLX after 7 days	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	0.15286112783906058	[19,19]	[20,21]	5	hSpCas9	positive selection	3155482
49077891	49077914		-	24336571	A375	resistance to PLX after 14 days	AGGCTGCTTTTGCTGCGCCATGG	WDR45	ENSG00000196998	0.3847156649097966	[17,15]	[10,8]	4	hSpCas9	positive selection	3213273
49076740	49076763		-	24336571	A375	resistance to PLX after 14 days	CCTGCCCAGCAGTGCTGATCTGG	WDR45	ENSG00000196998	-0.18782951460866393	[48,31]	[14,17]	-2	hSpCas9	positive selection	3213274
49076654	49076677		+	24336571	A375	resistance to PLX after 14 days	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	1.200088136859424	[23,18]	[25,20]	8	hSpCas9	positive selection	3213275
49077891	49077914		-	24336571	A375	viability after 7 days	AGGCTGCTTTTGCTGCGCCATGG	WDR45	ENSG00000196998	-0.10804155478222394	[18]	[19,13]	-1	hSpCas9	negative selection	3271066
49076740	49076763		-	24336571	A375	viability after 7 days	CCTGCCCAGCAGTGCTGATCTGG	WDR45	ENSG00000196998	0.8389413978724054	[23]	[41,39]	9	hSpCas9	negative selection	3271067
49076654	49076677		+	24336571	A375	viability after 7 days	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	0.08360288152914164	[19]	[19,19]	1	hSpCas9	negative selection	3271068
49077891	49077914		-	24336571	A375	viability after 14 days	AGGCTGCTTTTGCTGCGCCATGG	WDR45	ENSG00000196998	-0.11033504626425183	[18]	[17,15]	-1	hSpCas9	negative selection	3328859
49076740	49076763		-	24336571	A375	viability after 14 days	CCTGCCCAGCAGTGCTGATCTGG	WDR45	ENSG00000196998	0.8216382955153216	[23]	[48,31]	9	hSpCas9	negative selection	3328860
49076654	49076677		+	24336571	A375	viability after 14 days	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	0.2394099628194457	[19]	[23,18]	3	hSpCas9	negative selection	3328861
49076739	49076762	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTGCCCAGCAGTGCTGATCTGGG	WDR45	ENSG00000196998	1.9719239925835867	[38,38]	[0,0]	7	hSpCas9	positive selection	3401306
49077838	49077861	X	+	27383988	293T	resistance to West Nile virus (flavivirus)	CAGATGCCCCTTCTCCATCAAGG	WDR45	ENSG00000196998	-0.0735906666687818	[160,160]	[0,0]	0	hSpCas9	positive selection	3401307
49077864	49077887	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGGTGTGCGCATCTACAACGTGG	WDR45	ENSG00000196998	1.7337642553888224	[45,45]	[0,0]	7	hSpCas9	positive selection	3401308
49076460	49076483	X	+	26780180	HT29	viability (Avana library 4 designs)	ACAGCTTTCGGGGATTGTCGGGG	WDR45	ENSG00000196998	1.38560940852324	[]	[]	5	hSpCas9	negative selection	3471560
49077682	49077705	X	+	26780180	HT29	viability (Avana library 4 designs)	CCAAGGCCAGAAGGTTGGAGCGG	WDR45	ENSG00000196998	0.858509250729064	[]	[]	3	hSpCas9	negative selection	3471561
49076429	49076452	X	-	26780180	HT29	viability (Avana library 4 designs)	GATACCCGGGACAACCCCAAGGG	WDR45	ENSG00000196998	2.03512369902814	[]	[]	7	hSpCas9	negative selection	3471562
49076481	49076504	X	+	26780180	HT29	viability (Avana library 4 designs)	GGAAGGAGTACACATAGATGCGG	WDR45	ENSG00000196998	1.13925874605953	[]	[]	4	hSpCas9	negative selection	3471563
49077682	49077705	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCAAGGCCAGAAGGTTGGAGCGG	WDR45	ENSG00000196998	4.15319779925382	[]	[]	6	hSpCas9	negative selection	3578420
49076429	49076452	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	GATACCCGGGACAACCCCAAGGG	WDR45	ENSG00000196998	1.78056105195719	[]	[]	2	hSpCas9	negative selection	3578421
49076481	49076504	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGAAGGAGTACACATAGATGCGG	WDR45	ENSG00000196998	-0.594411152985903	[]	[]	0	hSpCas9	negative selection	3578422
49076460	49076483	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACAGCTTTCGGGGATTGTCGGGG	WDR45	ENSG00000196998	5.39109889074928	[]	[]	8	hSpCas9	negative selection	3578423
49077839	49077862	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGATGCCCCTTCTCCATCAAGGG	WDR45	ENSG00000196998	0.454474979817292	[]	[]	0	hSpCas9	negative selection	3578424
49077864	49077887	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGGTGTGCGCATCTACAACGTGG	WDR45	ENSG00000196998	1.95324787547728	[]	[]	3	hSpCas9	negative selection	3578425
49077682	49077705	X	+	26780180	A375	viability (Avana lentiGuide)	CCAAGGCCAGAAGGTTGGAGCGG	WDR45	ENSG00000196998	-5.60057274662148	[]	[]	-8	hSpCas9	negative selection	3687079
49076429	49076452	X	-	26780180	A375	viability (Avana lentiGuide)	GATACCCGGGACAACCCCAAGGG	WDR45	ENSG00000196998	1.0992362688338	[]	[]	1	hSpCas9	negative selection	3687080
49076481	49076504	X	+	26780180	A375	viability (Avana lentiGuide)	GGAAGGAGTACACATAGATGCGG	WDR45	ENSG00000196998	7.07618965395019	[]	[]	5	hSpCas9	negative selection	3687081
49076460	49076483	X	+	26780180	A375	viability (Avana lentiGuide)	ACAGCTTTCGGGGATTGTCGGGG	WDR45	ENSG00000196998	-3.68471666140425	[]	[]	-6	hSpCas9	negative selection	3687082
49077839	49077862	X	+	26780180	A375	viability (Avana lentiGuide)	AGATGCCCCTTCTCCATCAAGGG	WDR45	ENSG00000196998	-0.876057271163568	[]	[]	-1	hSpCas9	negative selection	3687083
49077864	49077887	X	-	26780180	A375	viability (Avana lentiGuide)	AGGTGTGCGCATCTACAACGTGG	WDR45	ENSG00000196998	4.07181338147672	[]	[]	4	hSpCas9	negative selection	3687084
49077682	49077705	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCAAGGCCAGAAGGTTGGAGCGG	WDR45	ENSG00000196998	0.2943492285538384	[4]	[5,4]	8	hSpCas9	positive selection	3795686
49076429	49076452	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATACCCGGGACAACCCCAAGGG	WDR45	ENSG00000196998	0.03638857551145956	[5]	[5,5]	0	hSpCas9	positive selection	3795687
49076481	49076504	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAAGGAGTACACATAGATGCGG	WDR45	ENSG00000196998	-0.04854169655609595	[5]	[5,4]	-1	hSpCas9	positive selection	3795688
49076460	49076483	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACAGCTTTCGGGGATTGTCGGGG	WDR45	ENSG00000196998	0.2044907538196718	[4]	[5,4]	5	hSpCas9	positive selection	3795689
49077839	49077862	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGATGCCCCTTCTCCATCAAGGG	WDR45	ENSG00000196998	-0.010932435992625722	[5]	[6,4]	0	hSpCas9	positive selection	3795690
49077864	49077887	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGGTGTGCGCATCTACAACGTGG	WDR45	ENSG00000196998	0.07185495195583702	[5]	[6,5]	1	hSpCas9	positive selection	3795691
49077682	49077705	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCAAGGCCAGAAGGTTGGAGCGG	WDR45	ENSG00000196998	-0.08448769646651211	[4]	[1,4]	-1	hSpCas9	positive selection	3904293
49076429	49076452	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATACCCGGGACAACCCCAAGGG	WDR45	ENSG00000196998	-0.43239262900032643	[5]	[4,1]	-5	hSpCas9	positive selection	3904294
49076481	49076504	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAAGGAGTACACATAGATGCGG	WDR45	ENSG00000196998	-0.015333289603248715	[6]	[4,5]	0	hSpCas9	positive selection	3904295
49076460	49076483	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACAGCTTTCGGGGATTGTCGGGG	WDR45	ENSG00000196998	0.21245667712130953	[3]	[3,3]	5	hSpCas9	positive selection	3904296
49077839	49077862	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGATGCCCCTTCTCCATCAAGGG	WDR45	ENSG00000196998	0.17285241050167893	[6]	[5,6]	4	hSpCas9	positive selection	3904297
49077864	49077887	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGGTGTGCGCATCTACAACGTGG	WDR45	ENSG00000196998	0.10770361108542809	[7]	[6,6]	2	hSpCas9	positive selection	3904298
49077838	49077861	X	+	26780180	A375	viability	CAGATGCCCCTTCTCCATCAAGG	WDR45	ENSG00000196998	1.2369489742779	[]	[]	6	hSpCas9	negative selection	4012378
49076654	49076677	X	+	26780180	A375	viability	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	1.35511170136678	[]	[]	7	hSpCas9	negative selection	4012379
49076739	49076762	X	-	26780180	A375	viability	CTGCCCAGCAGTGCTGATCTGGG	WDR45	ENSG00000196998	0.65276576831299	[]	[]	2	hSpCas9	negative selection	4012380
49076448	49076471	X	+	26780180	A375	viability	TATCAAACTCAAACAGCTTTCGG	WDR45	ENSG00000196998	0.160442041451417	[]	[]	0	hSpCas9	negative selection	4012381
49076424	49076447	X	+	26780180	A375	viability	TCTCACCCTTGGGGTTGTCCCGG	WDR45	ENSG00000196998	1.51120143031784	[]	[]	8	hSpCas9	negative selection	4012382
49077838	49077861	X	+	26780180	HT29	viability (GeCKOv2 library)	CAGATGCCCCTTCTCCATCAAGG	WDR45	ENSG00000196998	1.41627305261058	[]	[]	7	hSpCas9	negative selection	4120344
49076654	49076677	X	+	26780180	HT29	viability (GeCKOv2 library)	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	0.658233668979902	[]	[]	2	hSpCas9	negative selection	4120345
49076739	49076762	X	-	26780180	HT29	viability (GeCKOv2 library)	CTGCCCAGCAGTGCTGATCTGGG	WDR45	ENSG00000196998	0.644544108869802	[]	[]	2	hSpCas9	negative selection	4120346
49076448	49076471	X	+	26780180	HT29	viability (GeCKOv2 library)	TATCAAACTCAAACAGCTTTCGG	WDR45	ENSG00000196998	0.120688426116961	[]	[]	0	hSpCas9	negative selection	4120347
49076424	49076447	X	+	26780180	HT29	viability (GeCKOv2 library)	TCTCACCCTTGGGGTTGTCCCGG	WDR45	ENSG00000196998	2.18639580428049	[]	[]	9	hSpCas9	negative selection	4120348
49077891	49077914	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGGCTGCTTTTGCTGCGCCATGG	WDR45	ENSG00000196998	0.23687696449480547	[3]	[2,3]	6	hSpCas9	positive selection	4182258
49076740	49076763	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCTGCCCAGCAGTGCTGATCTGG	WDR45	ENSG00000196998	0.2566638389712529	[4]	[3,3]	6	hSpCas9	positive selection	4182259
49076654	49076677	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	0.5817092816148897	[4]	[4,4]	9	hSpCas9	positive selection	4182260
49077891	49077914	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGGCTGCTTTTGCTGCGCCATGG	WDR45	ENSG00000196998	0.8614297737055551	[4]	[0,2,3,4]	5	hSpCas9	positive selection	4246280
49076740	49076763	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCTGCCCAGCAGTGCTGATCTGG	WDR45	ENSG00000196998	1.1046946655644152	[4]	[4,2,4,3]	8	hSpCas9	positive selection	4246281
49076654	49076677	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	1.0773044528004305	[4]	[5,2,2,4]	7	hSpCas9	positive selection	4246282
49076654	49076677	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	0.042966587205019315	[2]	[3,1]	0	hSpCas9	positive selection	4307714
49076424	49076447	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTCACCCTTGGGGTTGTCCCGG	WDR45	ENSG00000196998	-0.0032257975850563114	[2]	[2,1]	0	hSpCas9	positive selection	4307715
49076448	49076471	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TATCAAACTCAAACAGCTTTCGG	WDR45	ENSG00000196998	0.409465191894096	[3]	[4,3]	8	hSpCas9	positive selection	4307716
49076739	49076762	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGCCCAGCAGTGCTGATCTGGG	WDR45	ENSG00000196998	0.18753491784912302	[1]	[1,0]	4	hSpCas9	positive selection	4371962
49077838	49077861	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGATGCCCCTTCTCCATCAAGG	WDR45	ENSG00000196998	0.04327768753542076	[2]	[2,1]	0	hSpCas9	positive selection	4371963
49076429	49076451	X	-	27760321	OCIAML3	viability	ATACCCGGGACAACCCCAAGGG	WDR45	ENSG00000196998	0.11468616898587347	[296,243]	[207,253]	1	hSpCas9	negative selection	4453943
49076443	49076465	X	-	27760321	OCIAML3	viability	GCTGTTTGAGTTTGATACCCGG	WDR45	ENSG00000196998	-0.3971771265209661	[434,398]	[201,306]	-4	hSpCas9	negative selection	4453944
49076482	49076504	X	+	27760321	OCIAML3	viability	GAAGGAGTACACATAGATGCGG	WDR45	ENSG00000196998	0.5453408552718542	[42,51]	[46,64]	6	hSpCas9	negative selection	4453945
49076736	49076758	X	+	27760321	OCIAML3	viability	CGTCCCAGATCAGCACTGCTGG	WDR45	ENSG00000196998	0.041998814508333204	[820,690]	[572,649]	0	hSpCas9	negative selection	4453946
49077733	49077755	X	-	27760321	OCIAML3	viability	TGTCCAGACCACGAGCAGGTGG	WDR45	ENSG00000196998	0.6891161773943542	[665,557]	[683,878]	7	hSpCas9	negative selection	4453947
49076429	49076451	X	-	27760321	OCIAML2	viability	ATACCCGGGACAACCCCAAGGG	WDR45	ENSG00000196998	0.09427277678908952	[296,243]	[181,298]	1	hSpCas9	negative selection	4537406
49076443	49076465	X	-	27760321	OCIAML2	viability	GCTGTTTGAGTTTGATACCCGG	WDR45	ENSG00000196998	-0.7167937066968872	[434,398]	[196,215]	-6	hSpCas9	negative selection	4537407
49076482	49076504	X	+	27760321	OCIAML2	viability	GAAGGAGTACACATAGATGCGG	WDR45	ENSG00000196998	-1.2451229352951518	[42,51]	[21,8]	-8	hSpCas9	negative selection	4537408
49076736	49076758	X	+	27760321	OCIAML2	viability	CGTCCCAGATCAGCACTGCTGG	WDR45	ENSG00000196998	0.4040296227232154	[820,690]	[737,895]	5	hSpCas9	negative selection	4537409
49077733	49077755	X	-	27760321	OCIAML2	viability	TGTCCAGACCACGAGCAGGTGG	WDR45	ENSG00000196998	0.3953970434895502	[665,557]	[642,655]	5	hSpCas9	negative selection	4537410
49076429	49076451	X	-	27760321	MV411	viability	ATACCCGGGACAACCCCAAGGG	WDR45	ENSG00000196998	0.5832827436916816	[296,243]	[230,318]	4	hSpCas9	negative selection	4620869
49076443	49076465	X	-	27760321	MV411	viability	GCTGTTTGAGTTTGATACCCGG	WDR45	ENSG00000196998	1.662612123428159	[434,398]	[581,1304]	9	hSpCas9	negative selection	4620870
49076482	49076504	X	+	27760321	MV411	viability	GAAGGAGTACACATAGATGCGG	WDR45	ENSG00000196998	-0.7392528380107031	[42,51]	[0,45]	-5	hSpCas9	negative selection	4620871
49076736	49076758	X	+	27760321	MV411	viability	CGTCCCAGATCAGCACTGCTGG	WDR45	ENSG00000196998	0.39525084681091527	[820,690]	[464,936]	3	hSpCas9	negative selection	4620872
49077733	49077755	X	-	27760321	MV411	viability	TGTCCAGACCACGAGCAGGTGG	WDR45	ENSG00000196998	0.3376869988756215	[665,557]	[204,963]	2	hSpCas9	negative selection	4620873
49076429	49076451	X	-	27760321	HL60	viability	ATACCCGGGACAACCCCAAGGG	WDR45	ENSG00000196998	-0.4312903487686871	[296,243]	[165,159]	-5	hSpCas9	negative selection	4704332
49076443	49076465	X	-	27760321	HL60	viability	GCTGTTTGAGTTTGATACCCGG	WDR45	ENSG00000196998	-0.19287663736908223	[434,398]	[361,229]	-2	hSpCas9	negative selection	4704333
49076482	49076504	X	+	27760321	HL60	viability	GAAGGAGTACACATAGATGCGG	WDR45	ENSG00000196998	-1.8460554183810949	[42,51]	[7,13]	-9	hSpCas9	negative selection	4704334
49076736	49076758	X	+	27760321	HL60	viability	CGTCCCAGATCAGCACTGCTGG	WDR45	ENSG00000196998	0.2649738400717081	[820,690]	[714,764]	3	hSpCas9	negative selection	4704335
49077733	49077755	X	-	27760321	HL60	viability	TGTCCAGACCACGAGCAGGTGG	WDR45	ENSG00000196998	0.9431365792431472	[665,557]	[854,1065]	8	hSpCas9	negative selection	4704336
49076429	49076451	X	-	27760321	HT1080	viability	ATACCCGGGACAACCCCAAGGG	WDR45	ENSG00000196998	0.8119297635268669	[243,190]	[133,171]	4	hSpCas9	negative selection	4787795
49076443	49076465	X	-	27760321	HT1080	viability	GCTGTTTGAGTTTGATACCCGG	WDR45	ENSG00000196998	-0.10731221485357578	[398,311]	[88,177]	0	hSpCas9	negative selection	4787796
49076482	49076504	X	+	27760321	HT1080	viability	GAAGGAGTACACATAGATGCGG	WDR45	ENSG00000196998	-4.2122524602739	[51,40]	[0,0]	-8	hSpCas9	negative selection	4787797
49076736	49076758	X	+	27760321	HT1080	viability	CGTCCCAGATCAGCACTGCTGG	WDR45	ENSG00000196998	1.066092216023811	[690,538]	[416,617]	6	hSpCas9	negative selection	4787798
49077733	49077755	X	-	27760321	HT1080	viability	TGTCCAGACCACGAGCAGGTGG	WDR45	ENSG00000196998	1.5692412604065042	[557,435]	[683,481]	8	hSpCas9	negative selection	4787799
49076429	49076451	X	-	27760321	HT29	viability after 7 days	ATACCCGGGACAACCCCAAGGG	WDR45	ENSG00000196998	0.21267237399172267	[243,190]	[255,312,390]	3	hSpCas9	negative selection	4871258
49076443	49076465	X	-	27760321	HT29	viability after 7 days	GCTGTTTGAGTTTGATACCCGG	WDR45	ENSG00000196998	-0.032268298654757735	[398,311]	[471,330,537]	0	hSpCas9	negative selection	4871259
49076482	49076504	X	+	27760321	HT29	viability after 7 days	GAAGGAGTACACATAGATGCGG	WDR45	ENSG00000196998	0.8613735456403129	[51,40]	[126,171,31]	9	hSpCas9	negative selection	4871260
49076736	49076758	X	+	27760321	HT29	viability after 7 days	CGTCCCAGATCAGCACTGCTGG	WDR45	ENSG00000196998	0.11959050785984304	[690,538]	[849,784,936]	1	hSpCas9	negative selection	4871261
49077733	49077755	X	-	27760321	HT29	viability after 7 days	TGTCCAGACCACGAGCAGGTGG	WDR45	ENSG00000196998	0.722973553108625	[557,435]	[731,1557,833]	9	hSpCas9	negative selection	4871262
49076429	49076451	X	-	27760321	HT29	viability after 25 days	ATACCCGGGACAACCCCAAGGG	WDR45	ENSG00000196998	0.36785426085298784	[243,190]	[278,231,468]	4	hSpCas9	negative selection	4954721
49076443	49076465	X	-	27760321	HT29	viability after 25 days	GCTGTTTGAGTTTGATACCCGG	WDR45	ENSG00000196998	-0.02679759269362598	[398,311]	[273,442,496]	0	hSpCas9	negative selection	4954722
49076482	49076504	X	+	27760321	HT29	viability after 25 days	GAAGGAGTACACATAGATGCGG	WDR45	ENSG00000196998	-0.6727326705474654	[51,40]	[1,57,42]	-5	hSpCas9	negative selection	4954723
49076736	49076758	X	+	27760321	HT29	viability after 25 days	CGTCCCAGATCAGCACTGCTGG	WDR45	ENSG00000196998	0.7546679370723421	[690,538]	[1264,915,1390]	8	hSpCas9	negative selection	4954724
49077733	49077755	X	-	27760321	HT29	viability after 25 days	TGTCCAGACCACGAGCAGGTGG	WDR45	ENSG00000196998	1.1815283365366545	[557,435]	[827,1423,1680]	9	hSpCas9	negative selection	4954725
49076429	49076451	X	-	27760321	HT29	viability after 22 days	ATACCCGGGACAACCCCAAGGG	WDR45	ENSG00000196998	0.3970749564506348	[243,190]	[335,258,398]	4	hSpCas9	negative selection	5038184
49076443	49076465	X	-	27760321	HT29	viability after 22 days	GCTGTTTGAGTTTGATACCCGG	WDR45	ENSG00000196998	-0.5186322619531565	[398,311]	[184,335,342]	-5	hSpCas9	negative selection	5038185
49076482	49076504	X	+	27760321	HT29	viability after 22 days	GAAGGAGTACACATAGATGCGG	WDR45	ENSG00000196998	0.2931472255969605	[51,40]	[18,8,171]	3	hSpCas9	negative selection	5038186
49076736	49076758	X	+	27760321	HT29	viability after 22 days	CGTCCCAGATCAGCACTGCTGG	WDR45	ENSG00000196998	0.6781125095908929	[690,538]	[885,1122,1412]	7	hSpCas9	negative selection	5038187
49077733	49077755	X	-	27760321	HT29	viability after 22 days	TGTCCAGACCACGAGCAGGTGG	WDR45	ENSG00000196998	0.8818046819016274	[557,435]	[1099,936,1138]	8	hSpCas9	negative selection	5038188
49076429	49076451	X	-	27760321	HT29	viability after 19 days	ATACCCGGGACAACCCCAAGGG	WDR45	ENSG00000196998	0.9819572794683988	[243,190]	[139,400,880]	8	hSpCas9	negative selection	5121647
49076443	49076465	X	-	27760321	HT29	viability after 19 days	GCTGTTTGAGTTTGATACCCGG	WDR45	ENSG00000196998	-0.07843901391975415	[398,311]	[323,260,556]	0	hSpCas9	negative selection	5121648
49076482	49076504	X	+	27760321	HT29	viability after 19 days	GAAGGAGTACACATAGATGCGG	WDR45	ENSG00000196998	-0.1787296299598129	[51,40]	[145,1,4]	-2	hSpCas9	negative selection	5121649
49076736	49076758	X	+	27760321	HT29	viability after 19 days	CGTCCCAGATCAGCACTGCTGG	WDR45	ENSG00000196998	0.34126830441994493	[690,538]	[1239,469,994]	3	hSpCas9	negative selection	5121650
49077733	49077755	X	-	27760321	HT29	viability after 19 days	TGTCCAGACCACGAGCAGGTGG	WDR45	ENSG00000196998	1.2510977060194675	[557,435]	[1329,1244,1475]	9	hSpCas9	negative selection	5121651
49076429	49076451	X	-	27760321	HT29	viability after 16 days	ATACCCGGGACAACCCCAAGGG	WDR45	ENSG00000196998	0.19202854232078637	[243,190]	[203,203,420]	2	hSpCas9	negative selection	5205110
49076443	49076465	X	-	27760321	HT29	viability after 16 days	GCTGTTTGAGTTTGATACCCGG	WDR45	ENSG00000196998	-0.21086869348868204	[398,311]	[314,431,278]	-2	hSpCas9	negative selection	5205111
49076482	49076504	X	+	27760321	HT29	viability after 16 days	GAAGGAGTACACATAGATGCGG	WDR45	ENSG00000196998	-0.05899947407537853	[51,40]	[67,34,48]	0	hSpCas9	negative selection	5205112
49076736	49076758	X	+	27760321	HT29	viability after 16 days	CGTCCCAGATCAGCACTGCTGG	WDR45	ENSG00000196998	0.6814184155763026	[690,538]	[1401,884,1056]	7	hSpCas9	negative selection	5205113
49077733	49077755	X	-	27760321	HT29	viability after 16 days	TGTCCAGACCACGAGCAGGTGG	WDR45	ENSG00000196998	1.2318980810165947	[557,435]	[1301,1180,1437]	9	hSpCas9	negative selection	5205114
49076429	49076451	X	-	27760321	HT29	viability after 13 days	ATACCCGGGACAACCCCAAGGG	WDR45	ENSG00000196998	0.531570918270339	[243,190]	[610,53,424]	6	hSpCas9	negative selection	5288573
49076443	49076465	X	-	27760321	HT29	viability after 13 days	GCTGTTTGAGTTTGATACCCGG	WDR45	ENSG00000196998	-0.4660289240366071	[398,311]	[190,354,346]	-5	hSpCas9	negative selection	5288574
49076482	49076504	X	+	27760321	HT29	viability after 13 days	GAAGGAGTACACATAGATGCGG	WDR45	ENSG00000196998	0.3628217856926468	[51,40]	[120,66,22]	4	hSpCas9	negative selection	5288575
49076736	49076758	X	+	27760321	HT29	viability after 13 days	CGTCCCAGATCAGCACTGCTGG	WDR45	ENSG00000196998	0.49380208915242685	[690,538]	[1288,803,924]	6	hSpCas9	negative selection	5288576
49077733	49077755	X	-	27760321	HT29	viability after 13 days	TGTCCAGACCACGAGCAGGTGG	WDR45	ENSG00000196998	0.6634466886956667	[557,435]	[1124,1038,594]	8	hSpCas9	negative selection	5288577
49076429	49076451	X	-	27760321	HT29	viability after 10 days	ATACCCGGGACAACCCCAAGGG	WDR45	ENSG00000196998	0.013081803685857207	[243,190]	[347,316,160]	0	hSpCas9	negative selection	5372036
49076443	49076465	X	-	27760321	HT29	viability after 10 days	GCTGTTTGAGTTTGATACCCGG	WDR45	ENSG00000196998	-0.04059059712426981	[398,311]	[404,428,459]	0	hSpCas9	negative selection	5372037
49076482	49076504	X	+	27760321	HT29	viability after 10 days	GAAGGAGTACACATAGATGCGG	WDR45	ENSG00000196998	0.44041858844174	[51,40]	[2,122,110]	6	hSpCas9	negative selection	5372038
49076736	49076758	X	+	27760321	HT29	viability after 10 days	CGTCCCAGATCAGCACTGCTGG	WDR45	ENSG00000196998	0.3209438117943142	[690,538]	[794,846,1225]	4	hSpCas9	negative selection	5372039
49077733	49077755	X	-	27760321	HT29	viability after 10 days	TGTCCAGACCACGAGCAGGTGG	WDR45	ENSG00000196998	0.4915092580215058	[557,435]	[752,839,1019]	6	hSpCas9	negative selection	5372040
49076429	49076451	X	-	27760321	MOLM13	viability	ATACCCGGGACAACCCCAAGGG	WDR45	ENSG00000196998	-2.8208737688863845	[296,243]	[34,9]	-8	hSpCas9	negative selection	5455499
49076443	49076465	X	-	27760321	MOLM13	viability	GCTGTTTGAGTTTGATACCCGG	WDR45	ENSG00000196998	-1.7820051633124214	[434,398]	[89,49]	-7	hSpCas9	negative selection	5455500
49076482	49076504	X	+	27760321	MOLM13	viability	GAAGGAGTACACATAGATGCGG	WDR45	ENSG00000196998	-4.7599897900096915	[42,51]	[0,0]	-9	hSpCas9	negative selection	5455501
49076736	49076758	X	+	27760321	MOLM13	viability	CGTCCCAGATCAGCACTGCTGG	WDR45	ENSG00000196998	0.34110978946790826	[820,690]	[332,712]	2	hSpCas9	negative selection	5455502
49077733	49077755	X	-	27760321	MOLM13	viability	TGTCCAGACCACGAGCAGGTGG	WDR45	ENSG00000196998	0.7060100076784503	[665,557]	[990,194]	5	hSpCas9	negative selection	5455503
49079497	49079520	X	-	27661255	K562	viability	GGAGGGTGTAACTGAAAGAAAGG	WDR45	ENSG00000196998	0.15018283644077846	[1910,2144]	[1956,1654]	5	dCas9-KRAB	negative selection	5503897
49079514	49079537	X	-	27661255	K562	viability	GCATGAGGCATTCCAGTGGAGGG	WDR45	ENSG00000196998	0.1317541359704113	[1229,1340]	[1186,1068]	4	dCas9-KRAB	negative selection	5503898
49079896	49079919	X	-	27661255	K562	viability	GGCTCCCTCCCCCGGAAGTAGGG	WDR45	ENSG00000196998	0.12954168975688762	[927,1427]	[1088,963]	4	dCas9-KRAB	negative selection	5503899
49079497	49079520	X	-	27661255	K562	viability	GGAGGGTGTAACTGAAAGAAAGG	WDR45	ENSG00000196998	0.15018283644077846	[1910,2144]	[1956,1654]	5	dCas9-KRAB	negative selection	5522667
49079514	49079537	X	-	27661255	K562	viability	GCATGAGGCATTCCAGTGGAGGG	WDR45	ENSG00000196998	0.1317541359704113	[1229,1340]	[1186,1068]	4	dCas9-KRAB	negative selection	5522668
49079896	49079919	X	-	27661255	K562	viability	GGCTCCCTCCCCCGGAAGTAGGG	WDR45	ENSG00000196998	0.12954168975688762	[927,1427]	[1088,963]	4	dCas9-KRAB	negative selection	5522669
49076654	49076677	X	+	27260156	BXPC3	viability	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	0.4419954740392863	[439]	[573,531,673,741]	8	hSpCas9	negative selection	5580174
49076424	49076447	X	+	27260156	BXPC3	viability	TCTCACCCTTGGGGTTGTCCCGG	WDR45	ENSG00000196998	0.6726647279474455	[355]	[622,448,649,661]	9	hSpCas9	negative selection	5580175
49076448	49076471	X	+	27260156	BXPC3	viability	TATCAAACTCAAACAGCTTTCGG	WDR45	ENSG00000196998	0.37159828240467474	[730]	[989,904,919,1157]	7	hSpCas9	negative selection	5580176
49076739	49076762	X	-	27260156	BXPC3	viability	CTGCCCAGCAGTGCTGATCTGGG	WDR45	ENSG00000196998	0.06227687046367736	[70]	[72,31,111,98]	1	hSpCas9	negative selection	5644422
49077838	49077861	X	+	27260156	BXPC3	viability	CAGATGCCCCTTCTCCATCAAGG	WDR45	ENSG00000196998	0.3361878507912326	[399]	[501,487,510,623]	7	hSpCas9	negative selection	5644423
49076654	49076677	X	+	27260156	A673	viability	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	0.3083838062672995	[439]	[605,605,692,708]	7	hSpCas9	negative selection	5701425
49076424	49076447	X	+	27260156	A673	viability	TCTCACCCTTGGGGTTGTCCCGG	WDR45	ENSG00000196998	0.39960916375852357	[355]	[645,473,553,593]	8	hSpCas9	negative selection	5701426
49076448	49076471	X	+	27260156	A673	viability	TATCAAACTCAAACAGCTTTCGG	WDR45	ENSG00000196998	0.23290813433362179	[730]	[1191,921,965,1067]	5	hSpCas9	negative selection	5701427
49076739	49076762	X	-	27260156	A673	viability	CTGCCCAGCAGTGCTGATCTGGG	WDR45	ENSG00000196998	0.1683253401458744	[70]	[102,59,103,118]	4	hSpCas9	negative selection	5765673
49077838	49077861	X	+	27260156	A673	viability	CAGATGCCCCTTCTCCATCAAGG	WDR45	ENSG00000196998	0.20375328927324057	[399]	[549,637,521,495]	5	hSpCas9	negative selection	5765674
49076654	49076677	X	+	27260156	A375	viability	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	0.3012142754361881	[439]	[421,686,734,685]	4	hSpCas9	negative selection	5822676
49076424	49076447	X	+	27260156	A375	viability	TCTCACCCTTGGGGTTGTCCCGG	WDR45	ENSG00000196998	0.36369722472685206	[355]	[729,730,339,383]	5	hSpCas9	negative selection	5822677
49076448	49076471	X	+	27260156	A375	viability	TATCAAACTCAAACAGCTTTCGG	WDR45	ENSG00000196998	0.3633884246694451	[730]	[1114,1167,1294,850]	5	hSpCas9	negative selection	5822678
49076739	49076762	X	-	27260156	A375	viability	CTGCCCAGCAGTGCTGATCTGGG	WDR45	ENSG00000196998	-0.40101267205311775	[70]	[34,48,84,77]	-5	hSpCas9	negative selection	5886924
49077838	49077861	X	+	27260156	A375	viability	CAGATGCCCCTTCTCCATCAAGG	WDR45	ENSG00000196998	-0.32052765097232205	[399]	[381,385,467,272]	-4	hSpCas9	negative selection	5886925
49076654	49076677	X	+	27260156	COLO741	viability	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	0.4529554042197414	[439]	[807,758,744]	8	hSpCas9	negative selection	5943927
49076424	49076447	X	+	27260156	COLO741	viability	TCTCACCCTTGGGGTTGTCCCGG	WDR45	ENSG00000196998	0.5275228064710761	[355]	[723,616,631]	9	hSpCas9	negative selection	5943928
49076448	49076471	X	+	27260156	COLO741	viability	TATCAAACTCAAACAGCTTTCGG	WDR45	ENSG00000196998	0.2964882385482297	[730]	[1031,1316,1084]	6	hSpCas9	negative selection	5943929
49076739	49076762	X	-	27260156	COLO741	viability	CTGCCCAGCAGTGCTGATCTGGG	WDR45	ENSG00000196998	0.06621997525108059	[70]	[139,102,48]	1	hSpCas9	negative selection	6008175
49077838	49077861	X	+	27260156	COLO741	viability	CAGATGCCCCTTCTCCATCAAGG	WDR45	ENSG00000196998	0.19095586707262613	[399]	[509,553,671]	4	hSpCas9	negative selection	6008176
49076654	49076677	X	+	27260156	CAL120	viability	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	0.07945256093088317	[439]	[565,562,603]	1	hSpCas9	negative selection	6065178
49076424	49076447	X	+	27260156	CAL120	viability	TCTCACCCTTGGGGTTGTCCCGG	WDR45	ENSG00000196998	0.41635545632001625	[355]	[515,762,484]	6	hSpCas9	negative selection	6065179
49076448	49076471	X	+	27260156	CAL120	viability	TATCAAACTCAAACAGCTTTCGG	WDR45	ENSG00000196998	0.44654806414271075	[730]	[1241,1137,1336]	6	hSpCas9	negative selection	6065180
49076739	49076762	X	-	27260156	CAL120	viability	CTGCCCAGCAGTGCTGATCTGGG	WDR45	ENSG00000196998	0.541954324453819	[70]	[57,231,85]	7	hSpCas9	negative selection	6129426
49077838	49077861	X	+	27260156	CAL120	viability	CAGATGCCCCTTCTCCATCAAGG	WDR45	ENSG00000196998	0.4581493076500875	[399]	[945,651,495]	7	hSpCas9	negative selection	6129427
49076654	49076677	X	+	27260156	CADOES1	viability	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	0.11753994699258546	[439]	[462,487,403,419]	2	hSpCas9	negative selection	6186429
49076424	49076447	X	+	27260156	CADOES1	viability	TCTCACCCTTGGGGTTGTCCCGG	WDR45	ENSG00000196998	0.5774959705289591	[355]	[430,434,548,563]	8	hSpCas9	negative selection	6186430
49076448	49076471	X	+	27260156	CADOES1	viability	TATCAAACTCAAACAGCTTTCGG	WDR45	ENSG00000196998	0.4176269136168066	[730]	[825,763,1015,1030]	7	hSpCas9	negative selection	6186431
49076739	49076762	X	-	27260156	CADOES1	viability	CTGCCCAGCAGTGCTGATCTGGG	WDR45	ENSG00000196998	-0.35974704903975585	[70]	[36,88,52,25]	-6	hSpCas9	negative selection	6250677
49077838	49077861	X	+	27260156	CADOES1	viability	CAGATGCCCCTTCTCCATCAAGG	WDR45	ENSG00000196998	-0.09774601868707342	[399]	[382,260,457,285]	-2	hSpCas9	negative selection	6250678
49076654	49076677	X	+	27260156	EWS502	viability	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	0.5178088167573276	[439]	[623,717,652,674]	8	hSpCas9	negative selection	6307680
49076424	49076447	X	+	27260156	EWS502	viability	TCTCACCCTTGGGGTTGTCCCGG	WDR45	ENSG00000196998	0.6750265796637245	[355]	[595,564,382,880]	9	hSpCas9	negative selection	6307681
49076448	49076471	X	+	27260156	EWS502	viability	TATCAAACTCAAACAGCTTTCGG	WDR45	ENSG00000196998	0.4625733127015993	[730]	[935,720,1329,1328]	7	hSpCas9	negative selection	6307682
49076739	49076762	X	-	27260156	EWS502	viability	CTGCCCAGCAGTGCTGATCTGGG	WDR45	ENSG00000196998	-0.02672757618075572	[70]	[74,39,54,129]	0	hSpCas9	negative selection	6371928
49077838	49077861	X	+	27260156	EWS502	viability	CAGATGCCCCTTCTCCATCAAGG	WDR45	ENSG00000196998	0.08743051125046403	[399]	[403,366,535,505]	1	hSpCas9	negative selection	6371929
49076654	49076677	X	+	27260156	EW8	viability	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	0.3392807486296913	[439]	[460,497,436,410]	6	hSpCas9	negative selection	6428931
49076424	49076447	X	+	27260156	EW8	viability	TCTCACCCTTGGGGTTGTCCCGG	WDR45	ENSG00000196998	0.20989904445420757	[355]	[263,501,238,337]	4	hSpCas9	negative selection	6428932
49076448	49076471	X	+	27260156	EW8	viability	TATCAAACTCAAACAGCTTTCGG	WDR45	ENSG00000196998	0.4123514840558048	[730]	[1049,534,859,721]	7	hSpCas9	negative selection	6428933
49076739	49076762	X	-	27260156	EW8	viability	CTGCCCAGCAGTGCTGATCTGGG	WDR45	ENSG00000196998	-0.26566310802320636	[70]	[22,28,37,99]	-5	hSpCas9	negative selection	6493179
49077838	49077861	X	+	27260156	EW8	viability	CAGATGCCCCTTCTCCATCAAGG	WDR45	ENSG00000196998	0.14746436484432424	[399]	[443,281,293,434]	2	hSpCas9	negative selection	6493180
49076654	49076677	X	+	27260156	CORL105	viability	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	0.3827709703808299	[439]	[647,789,599,633]	7	hSpCas9	negative selection	6550182
49076424	49076447	X	+	27260156	CORL105	viability	TCTCACCCTTGGGGTTGTCCCGG	WDR45	ENSG00000196998	0.7703384621936209	[355]	[724,766,692,654]	9	hSpCas9	negative selection	6550183
49076448	49076471	X	+	27260156	CORL105	viability	TATCAAACTCAAACAGCTTTCGG	WDR45	ENSG00000196998	0.2667879149897904	[730]	[1056,1009,1145,924]	5	hSpCas9	negative selection	6550184
49076739	49076762	X	-	27260156	CORL105	viability	CTGCCCAGCAGTGCTGATCTGGG	WDR45	ENSG00000196998	-0.2523736178527223	[70]	[90,78,89,22]	-5	hSpCas9	negative selection	6614430
49077838	49077861	X	+	27260156	CORL105	viability	CAGATGCCCCTTCTCCATCAAGG	WDR45	ENSG00000196998	-0.11110177181842898	[399]	[447,371,485,437]	-2	hSpCas9	negative selection	6614431
49076654	49076677	X	+	27260156	HS294T	viability	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	0.6318261774863887	[439]	[262,220,297,274]	8	hSpCas9	negative selection	6671433
49076424	49076447	X	+	27260156	HS294T	viability	TCTCACCCTTGGGGTTGTCCCGG	WDR45	ENSG00000196998	0.9739747008055581	[355]	[165,430,278,196]	9	hSpCas9	negative selection	6671434
49076448	49076471	X	+	27260156	HS294T	viability	TATCAAACTCAAACAGCTTTCGG	WDR45	ENSG00000196998	0.3751563666696839	[730]	[406,396,294,359]	5	hSpCas9	negative selection	6671435
49076739	49076762	X	-	27260156	HS294T	viability	CTGCCCAGCAGTGCTGATCTGGG	WDR45	ENSG00000196998	-0.43556885226366493	[70]	[24,13,15,26]	-6	hSpCas9	negative selection	6735681
49077838	49077861	X	+	27260156	HS294T	viability	CAGATGCCCCTTCTCCATCAAGG	WDR45	ENSG00000196998	0.184489855060024	[399]	[121,249,137,198]	2	hSpCas9	negative selection	6735682
49076654	49076677	X	+	27260156	HCC44	viability	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	-0.12937587231358377	[439]	[612,311,437,483]	-2	hSpCas9	negative selection	6792684
49076424	49076447	X	+	27260156	HCC44	viability	TCTCACCCTTGGGGTTGTCCCGG	WDR45	ENSG00000196998	0.4776536658939942	[355]	[471,452,681,655]	7	hSpCas9	negative selection	6792685
49076448	49076471	X	+	27260156	HCC44	viability	TATCAAACTCAAACAGCTTTCGG	WDR45	ENSG00000196998	0.37685989218548255	[730]	[1421,887,1111,932]	6	hSpCas9	negative selection	6792686
49076739	49076762	X	-	27260156	HCC44	viability	CTGCCCAGCAGTGCTGATCTGGG	WDR45	ENSG00000196998	-0.2587957021627809	[70]	[38,52,51,118]	-4	hSpCas9	negative selection	6856932
49077838	49077861	X	+	27260156	HCC44	viability	CAGATGCCCCTTCTCCATCAAGG	WDR45	ENSG00000196998	0.3504798493798426	[399]	[476,397,985,529]	6	hSpCas9	negative selection	6856933
49076654	49076677	X	+	27260156	G402	viability	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	0.5633833846489654	[439]	[636,1046,460,1006]	7	hSpCas9	negative selection	6913935
49076424	49076447	X	+	27260156	G402	viability	TCTCACCCTTGGGGTTGTCCCGG	WDR45	ENSG00000196998	0.378022786172384	[355]	[960,222,453,650]	5	hSpCas9	negative selection	6913936
49076448	49076471	X	+	27260156	G402	viability	TATCAAACTCAAACAGCTTTCGG	WDR45	ENSG00000196998	0.42556579681898576	[730]	[1465,1706,873,826]	5	hSpCas9	negative selection	6913937
49076739	49076762	X	-	27260156	G402	viability	CTGCCCAGCAGTGCTGATCTGGG	WDR45	ENSG00000196998	-0.42964794239261783	[70]	[207,31,15,21]	-5	hSpCas9	negative selection	6978183
49077838	49077861	X	+	27260156	G402	viability	CAGATGCCCCTTCTCCATCAAGG	WDR45	ENSG00000196998	-0.06186988350128644	[399]	[454,779,438,222]	-1	hSpCas9	negative selection	6978184
49076654	49076677	X	+	27260156	L33	viability	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	0.16270056260694	[439]	[648,191,326,329]	3	hSpCas9	negative selection	7035186
49076424	49076447	X	+	27260156	L33	viability	TCTCACCCTTGGGGTTGTCCCGG	WDR45	ENSG00000196998	0.5508967077831026	[355]	[559,243,274,491]	9	hSpCas9	negative selection	7035187
49076448	49076471	X	+	27260156	L33	viability	TATCAAACTCAAACAGCTTTCGG	WDR45	ENSG00000196998	0.10712172252198304	[730]	[829,280,477,870]	2	hSpCas9	negative selection	7035188
49076739	49076762	X	-	27260156	L33	viability	CTGCCCAGCAGTGCTGATCTGGG	WDR45	ENSG00000196998	-0.01519100834000442	[70]	[105,33,30,41]	0	hSpCas9	negative selection	7099434
49077838	49077861	X	+	27260156	L33	viability	CAGATGCCCCTTCTCCATCAAGG	WDR45	ENSG00000196998	0.06273943285354297	[399]	[460,156,240,441]	1	hSpCas9	negative selection	7099435
49076654	49076677	X	+	27260156	K562	viability	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	0.7917836494202677	[439]	[868,921,547,420]	8	hSpCas9	negative selection	7156437
49076424	49076447	X	+	27260156	K562	viability	TCTCACCCTTGGGGTTGTCCCGG	WDR45	ENSG00000196998	0.38863291060280747	[355]	[324,628,329,376]	5	hSpCas9	negative selection	7156438
49076448	49076471	X	+	27260156	K562	viability	TATCAAACTCAAACAGCTTTCGG	WDR45	ENSG00000196998	0.08226273530858763	[730]	[854,667,509,719]	1	hSpCas9	negative selection	7156439
49076739	49076762	X	-	27260156	K562	viability	CTGCCCAGCAGTGCTGATCTGGG	WDR45	ENSG00000196998	0.17512318029810148	[70]	[33,70,121,55]	2	hSpCas9	negative selection	7220685
49077838	49077861	X	+	27260156	K562	viability	CAGATGCCCCTTCTCCATCAAGG	WDR45	ENSG00000196998	0.04875526133510005	[399]	[347,596,385,169]	0	hSpCas9	negative selection	7220686
49076654	49076677	X	+	27260156	HT29	viability	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	0.2100559925566241	[439]	[582,721,584,589]	4	hSpCas9	negative selection	7277688
49076424	49076447	X	+	27260156	HT29	viability	TCTCACCCTTGGGGTTGTCCCGG	WDR45	ENSG00000196998	0.4497898604684555	[355]	[678,596,470,616]	8	hSpCas9	negative selection	7277689
49076448	49076471	X	+	27260156	HT29	viability	TATCAAACTCAAACAGCTTTCGG	WDR45	ENSG00000196998	0.4754702638416529	[730]	[1480,1317,1005,1162]	8	hSpCas9	negative selection	7277690
49076739	49076762	X	-	27260156	HT29	viability	CTGCCCAGCAGTGCTGATCTGGG	WDR45	ENSG00000196998	-0.2987594171331409	[70]	[60,71,88,58]	-5	hSpCas9	negative selection	7341936
49077838	49077861	X	+	27260156	HT29	viability	CAGATGCCCCTTCTCCATCAAGG	WDR45	ENSG00000196998	0.09895821549928313	[399]	[555,621,394,517]	2	hSpCas9	negative selection	7341937
49076654	49076677	X	+	27260156	MHHES1	viability	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	0.07596440286048314	[439]	[695,387,592,429]	1	hSpCas9	negative selection	7398939
49076424	49076447	X	+	27260156	MHHES1	viability	TCTCACCCTTGGGGTTGTCCCGG	WDR45	ENSG00000196998	0.43992113872021554	[355]	[554,635,640,380]	7	hSpCas9	negative selection	7398940
49076448	49076471	X	+	27260156	MHHES1	viability	TATCAAACTCAAACAGCTTTCGG	WDR45	ENSG00000196998	0.4788280635790142	[730]	[1778,1238,873,829]	8	hSpCas9	negative selection	7398941
49076739	49076762	X	-	27260156	MHHES1	viability	CTGCCCAGCAGTGCTGATCTGGG	WDR45	ENSG00000196998	0.8737559967761228	[70]	[172,143,68,188]	9	hSpCas9	negative selection	7463187
49077838	49077861	X	+	27260156	MHHES1	viability	CAGATGCCCCTTCTCCATCAAGG	WDR45	ENSG00000196998	0.16041025696094208	[399]	[707,436,682,252]	3	hSpCas9	negative selection	7463188
49076654	49076677	X	+	27260156	MEWO	viability	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	0.3225336560093896	[439]	[732,409,443]	7	hSpCas9	negative selection	7520190
49076424	49076447	X	+	27260156	MEWO	viability	TCTCACCCTTGGGGTTGTCCCGG	WDR45	ENSG00000196998	0.7141286718107431	[355]	[638,539,477]	9	hSpCas9	negative selection	7520191
49076448	49076471	X	+	27260156	MEWO	viability	TATCAAACTCAAACAGCTTTCGG	WDR45	ENSG00000196998	0.19131409192380133	[730]	[956,692,726]	4	hSpCas9	negative selection	7520192
49076739	49076762	X	-	27260156	MEWO	viability	CTGCCCAGCAGTGCTGATCTGGG	WDR45	ENSG00000196998	-0.3537442025667241	[70]	[46,44,62]	-6	hSpCas9	negative selection	7584438
49077838	49077861	X	+	27260156	MEWO	viability	CAGATGCCCCTTCTCCATCAAGG	WDR45	ENSG00000196998	0.3146492454397378	[399]	[477,385,534]	6	hSpCas9	negative selection	7584439
49076654	49076677	X	+	27260156	LNCAPCLONEFGC	viability	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	0.5774239831282729	[439]	[671,642,581,474]	8	hSpCas9	negative selection	7641441
49076424	49076447	X	+	27260156	LNCAPCLONEFGC	viability	TCTCACCCTTGGGGTTGTCCCGG	WDR45	ENSG00000196998	0.6361197471215805	[355]	[428,517,482,571]	8	hSpCas9	negative selection	7641442
49076448	49076471	X	+	27260156	LNCAPCLONEFGC	viability	TATCAAACTCAAACAGCTTTCGG	WDR45	ENSG00000196998	0.4982445775120844	[730]	[917,891,1252,727]	7	hSpCas9	negative selection	7641443
49076739	49076762	X	-	27260156	LNCAPCLONEFGC	viability	CTGCCCAGCAGTGCTGATCTGGG	WDR45	ENSG00000196998	0.4160587509126321	[70]	[26,61,146,118]	6	hSpCas9	negative selection	7705689
49077838	49077861	X	+	27260156	LNCAPCLONEFGC	viability	CAGATGCCCCTTCTCCATCAAGG	WDR45	ENSG00000196998	0.06308037046966206	[399]	[362,391,389,369]	1	hSpCas9	negative selection	7705690
49076654	49076677	X	+	27260156	PANC0327	viability	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	0.6262554079935521	[439]	[438,544,1045,377]	8	hSpCas9	negative selection	7762692
49076424	49076447	X	+	27260156	PANC0327	viability	TCTCACCCTTGGGGTTGTCCCGG	WDR45	ENSG00000196998	0.6969058355226598	[355]	[641,303,586,554]	8	hSpCas9	negative selection	7762693
49076448	49076471	X	+	27260156	PANC0327	viability	TATCAAACTCAAACAGCTTTCGG	WDR45	ENSG00000196998	0.06291924859917286	[730]	[971,532,718,531]	0	hSpCas9	negative selection	7762694
49076739	49076762	X	-	27260156	PANC0327	viability	CTGCCCAGCAGTGCTGATCTGGG	WDR45	ENSG00000196998	1.399290556548357	[70]	[278,179,188,24]	9	hSpCas9	negative selection	7826940
49077838	49077861	X	+	27260156	PANC0327	viability	CAGATGCCCCTTCTCCATCAAGG	WDR45	ENSG00000196998	-0.16970698817828303	[399]	[377,180,353,372]	-3	hSpCas9	negative selection	7826941
49076654	49076677	X	+	27260156	NCIH2009	viability	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	0.37131255016412784	[439]	[896,814,691]	5	hSpCas9	negative selection	7883943
49076424	49076447	X	+	27260156	NCIH2009	viability	TCTCACCCTTGGGGTTGTCCCGG	WDR45	ENSG00000196998	0.9066877171422856	[355]	[929,785,1081]	9	hSpCas9	negative selection	7883944
49076448	49076471	X	+	27260156	NCIH2009	viability	TATCAAACTCAAACAGCTTTCGG	WDR45	ENSG00000196998	0.2429492488960967	[730]	[1257,1077,1299]	3	hSpCas9	negative selection	7883945
49076739	49076762	X	-	27260156	NCIH2009	viability	CTGCCCAGCAGTGCTGATCTGGG	WDR45	ENSG00000196998	0.4283015935050063	[70]	[100,122,169]	6	hSpCas9	negative selection	7948191
49077838	49077861	X	+	27260156	NCIH2009	viability	CAGATGCCCCTTCTCCATCAAGG	WDR45	ENSG00000196998	0.18026093067699356	[399]	[657,607,637]	2	hSpCas9	negative selection	7948192
49076654	49076677	X	+	27260156	NCIH1373	viability	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	0.8640961442054091	[439]	[1331,988,619,182]	8	hSpCas9	negative selection	8005194
49076424	49076447	X	+	27260156	NCIH1373	viability	TCTCACCCTTGGGGTTGTCCCGG	WDR45	ENSG00000196998	0.5328303301229853	[355]	[606,506,442,203]	5	hSpCas9	negative selection	8005195
49076448	49076471	X	+	27260156	NCIH1373	viability	TATCAAACTCAAACAGCTTTCGG	WDR45	ENSG00000196998	0.9005934243012533	[730]	[1498,1762,1271,407]	8	hSpCas9	negative selection	8005196
49076739	49076762	X	-	27260156	NCIH1373	viability	CTGCCCAGCAGTGCTGATCTGGG	WDR45	ENSG00000196998	0.9120178612740617	[70]	[264,64,104,50]	8	hSpCas9	negative selection	8069442
49077838	49077861	X	+	27260156	NCIH1373	viability	CAGATGCCCCTTCTCCATCAAGG	WDR45	ENSG00000196998	-0.2795813465423175	[399]	[241,533,321,88]	-3	hSpCas9	negative selection	8069443
49076654	49076677	X	+	27260156	PATU8902	viability	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	0.9914784793839414	[439]	[948,1179,1440,1241]	9	hSpCas9	negative selection	8126445
49076424	49076447	X	+	27260156	PATU8902	viability	TCTCACCCTTGGGGTTGTCCCGG	WDR45	ENSG00000196998	0.799509048174607	[355]	[1565,669,633,591]	8	hSpCas9	negative selection	8126446
49076448	49076471	X	+	27260156	PATU8902	viability	TATCAAACTCAAACAGCTTTCGG	WDR45	ENSG00000196998	0.9216816200782386	[730]	[1943,2098,1646,2102]	8	hSpCas9	negative selection	8126447
49076739	49076762	X	-	27260156	PATU8902	viability	CTGCCCAGCAGTGCTGATCTGGG	WDR45	ENSG00000196998	0.33182786179035517	[70]	[76,144,133,140]	3	hSpCas9	negative selection	8190693
49077838	49077861	X	+	27260156	PATU8902	viability	CAGATGCCCCTTCTCCATCAAGG	WDR45	ENSG00000196998	0.34182769893309106	[399]	[767,436,765,846]	3	hSpCas9	negative selection	8190694
49076654	49076677	X	+	27260156	PANC1	viability	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	0.5248489898567068	[439]	[682,465,459,537]	8	hSpCas9	negative selection	8247696
49076424	49076447	X	+	27260156	PANC1	viability	TCTCACCCTTGGGGTTGTCCCGG	WDR45	ENSG00000196998	0.6397788760982763	[355]	[385,656,520,387]	9	hSpCas9	negative selection	8247697
49076448	49076471	X	+	27260156	PANC1	viability	TATCAAACTCAAACAGCTTTCGG	WDR45	ENSG00000196998	0.534199742812061	[730]	[848,1201,803,838]	8	hSpCas9	negative selection	8247698
49076739	49076762	X	-	27260156	PANC1	viability	CTGCCCAGCAGTGCTGATCTGGG	WDR45	ENSG00000196998	0.24432648578552119	[70]	[37,10,91,125]	4	hSpCas9	negative selection	8311944
49077838	49077861	X	+	27260156	PANC1	viability	CAGATGCCCCTTCTCCATCAAGG	WDR45	ENSG00000196998	0.2919957971985965	[399]	[441,553,401,320]	5	hSpCas9	negative selection	8311945
49076654	49076677	X	+	27260156	PANC0813	viability	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	0.8768119615675597	[439]	[899,1054,836,994]	9	hSpCas9	negative selection	8368947
49076424	49076447	X	+	27260156	PANC0813	viability	TCTCACCCTTGGGGTTGTCCCGG	WDR45	ENSG00000196998	0.868255611100971	[355]	[591,1054,685,705]	9	hSpCas9	negative selection	8368948
49076448	49076471	X	+	27260156	PANC0813	viability	TATCAAACTCAAACAGCTTTCGG	WDR45	ENSG00000196998	0.33500285324997003	[730]	[998,1014,1113,1188]	5	hSpCas9	negative selection	8368949
49076739	49076762	X	-	27260156	PANC0813	viability	CTGCCCAGCAGTGCTGATCTGGG	WDR45	ENSG00000196998	0.37213763031832414	[70]	[74,145,159,50]	6	hSpCas9	negative selection	8433195
49077838	49077861	X	+	27260156	PANC0813	viability	CAGATGCCCCTTCTCCATCAAGG	WDR45	ENSG00000196998	0.423473059562795	[399]	[440,860,575,623]	6	hSpCas9	negative selection	8433196
49076654	49076677	X	+	27260156	RDES	viability	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	0.606901602823895	[439]	[626,663,986,841]	8	hSpCas9	negative selection	8490198
49076424	49076447	X	+	27260156	RDES	viability	TCTCACCCTTGGGGTTGTCCCGG	WDR45	ENSG00000196998	0.5251571782676473	[355]	[560,468,682,655]	8	hSpCas9	negative selection	8490199
49076448	49076471	X	+	27260156	RDES	viability	TATCAAACTCAAACAGCTTTCGG	WDR45	ENSG00000196998	0.4420252710664202	[730]	[951,959,1245,1491]	7	hSpCas9	negative selection	8490200
49076739	49076762	X	-	27260156	RDES	viability	CTGCCCAGCAGTGCTGATCTGGG	WDR45	ENSG00000196998	0.45913626067575875	[70]	[40,93,147,194]	7	hSpCas9	negative selection	8554446
49077838	49077861	X	+	27260156	RDES	viability	CAGATGCCCCTTCTCCATCAAGG	WDR45	ENSG00000196998	-0.053015570746249435	[399]	[421,347,546,462]	-1	hSpCas9	negative selection	8554447
49076654	49076677	X	+	27260156	PC3	viability	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	0.2757218634486533	[439]	[412,524,733,518]	6	hSpCas9	negative selection	8611449
49076424	49076447	X	+	27260156	PC3	viability	TCTCACCCTTGGGGTTGTCCCGG	WDR45	ENSG00000196998	0.6051680489213724	[355]	[309,506,976,591]	9	hSpCas9	negative selection	8611450
49076448	49076471	X	+	27260156	PC3	viability	TATCAAACTCAAACAGCTTTCGG	WDR45	ENSG00000196998	0.22409163324679993	[730]	[640,987,1071,769]	5	hSpCas9	negative selection	8611451
49076739	49076762	X	-	27260156	PC3	viability	CTGCCCAGCAGTGCTGATCTGGG	WDR45	ENSG00000196998	-0.21316159627021358	[70]	[34,65,118,51]	-5	hSpCas9	negative selection	8675697
49077838	49077861	X	+	27260156	PC3	viability	CAGATGCCCCTTCTCCATCAAGG	WDR45	ENSG00000196998	0.5782708819363224	[399]	[335,727,920,573]	9	hSpCas9	negative selection	8675698
49076654	49076677	X	+	27260156	PATU8988T	viability	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	0.41039622036157514	[439]	[650,541,509,554]	7	hSpCas9	negative selection	8732700
49076424	49076447	X	+	27260156	PATU8988T	viability	TCTCACCCTTGGGGTTGTCCCGG	WDR45	ENSG00000196998	0.3075720488494635	[355]	[451,506,325,426]	5	hSpCas9	negative selection	8732701
49076448	49076471	X	+	27260156	PATU8988T	viability	TATCAAACTCAAACAGCTTTCGG	WDR45	ENSG00000196998	0.2130425487496962	[730]	[851,874,523,1051]	3	hSpCas9	negative selection	8732702
49076739	49076762	X	-	27260156	PATU8988T	viability	CTGCCCAGCAGTGCTGATCTGGG	WDR45	ENSG00000196998	0.30674000308737925	[70]	[91,57,127,55]	5	hSpCas9	negative selection	8796948
49077838	49077861	X	+	27260156	PATU8988T	viability	CAGATGCCCCTTCTCCATCAAGG	WDR45	ENSG00000196998	0.3941955129174681	[399]	[692,442,377,513]	6	hSpCas9	negative selection	8796949
49076654	49076677	X	+	27260156	T47D	viability	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	0.39345116298916716	[439]	[683,499,774,749]	8	hSpCas9	negative selection	8853951
49076424	49076447	X	+	27260156	T47D	viability	TCTCACCCTTGGGGTTGTCCCGG	WDR45	ENSG00000196998	0.5126973103481853	[355]	[581,516,552,725]	9	hSpCas9	negative selection	8853952
49076448	49076471	X	+	27260156	T47D	viability	TATCAAACTCAAACAGCTTTCGG	WDR45	ENSG00000196998	0.28507859740145813	[730]	[1084,1088,927,1045]	6	hSpCas9	negative selection	8853953
49076739	49076762	X	-	27260156	T47D	viability	CTGCCCAGCAGTGCTGATCTGGG	WDR45	ENSG00000196998	0.06029797321272756	[70]	[102,73,105,61]	1	hSpCas9	negative selection	8918199
49077838	49077861	X	+	27260156	T47D	viability	CAGATGCCCCTTCTCCATCAAGG	WDR45	ENSG00000196998	0.3191042588936347	[399]	[596,602,562,559]	6	hSpCas9	negative selection	8918200
49076654	49076677	X	+	27260156	SU8686	viability	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	0.3347940960911286	[439]	[590,464,481,684]	5	hSpCas9	negative selection	8975202
49076424	49076447	X	+	27260156	SU8686	viability	TCTCACCCTTGGGGTTGTCCCGG	WDR45	ENSG00000196998	0.6920756291666142	[355]	[578,413,523,817]	9	hSpCas9	negative selection	8975203
49076448	49076471	X	+	27260156	SU8686	viability	TATCAAACTCAAACAGCTTTCGG	WDR45	ENSG00000196998	0.17986450661169728	[730]	[825,703,893,879]	3	hSpCas9	negative selection	8975204
49076739	49076762	X	-	27260156	SU8686	viability	CTGCCCAGCAGTGCTGATCTGGG	WDR45	ENSG00000196998	0.007131378317534409	[70]	[36,60,94,99]	0	hSpCas9	negative selection	9039450
49077838	49077861	X	+	27260156	SU8686	viability	CAGATGCCCCTTCTCCATCAAGG	WDR45	ENSG00000196998	0.05429752953813233	[399]	[393,388,369,510]	0	hSpCas9	negative selection	9039451
49076654	49076677	X	+	27260156	SKES1	viability	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	0.420552672549747	[439]	[720,640,537,481]	8	hSpCas9	negative selection	9096453
49076424	49076447	X	+	27260156	SKES1	viability	TCTCACCCTTGGGGTTGTCCCGG	WDR45	ENSG00000196998	0.5543727046911144	[355]	[678,698,387,376]	9	hSpCas9	negative selection	9096454
49076448	49076471	X	+	27260156	SKES1	viability	TATCAAACTCAAACAGCTTTCGG	WDR45	ENSG00000196998	0.28092000289979835	[730]	[841,999,742,950]	6	hSpCas9	negative selection	9096455
49076739	49076762	X	-	27260156	SKES1	viability	CTGCCCAGCAGTGCTGATCTGGG	WDR45	ENSG00000196998	-0.39708128603846404	[70]	[47,120,24,30]	-7	hSpCas9	negative selection	9160701
49077838	49077861	X	+	27260156	SKES1	viability	CAGATGCCCCTTCTCCATCAAGG	WDR45	ENSG00000196998	0.22600675799228	[399]	[487,644,438,330]	5	hSpCas9	negative selection	9160702
49076654	49076677	X	+	27260156	TOV112D	viability	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	0.35428434134142367	[439]	[398,1014,380,554]	6	hSpCas9	negative selection	9217704
49076424	49076447	X	+	27260156	TOV112D	viability	TCTCACCCTTGGGGTTGTCCCGG	WDR45	ENSG00000196998	0.11612232560319663	[355]	[471,464,405,232]	2	hSpCas9	negative selection	9217705
49076448	49076471	X	+	27260156	TOV112D	viability	TATCAAACTCAAACAGCTTTCGG	WDR45	ENSG00000196998	0.30927918970208723	[730]	[1065,1147,837,654]	6	hSpCas9	negative selection	9217706
49076739	49076762	X	-	27260156	TOV112D	viability	CTGCCCAGCAGTGCTGATCTGGG	WDR45	ENSG00000196998	0.20353127329532983	[70]	[102,107,56,67]	4	hSpCas9	negative selection	9281952
49077838	49077861	X	+	27260156	TOV112D	viability	CAGATGCCCCTTCTCCATCAAGG	WDR45	ENSG00000196998	0.09916776278518091	[399]	[433,454,564,272]	2	hSpCas9	negative selection	9281953
49076654	49076677	X	+	27260156	TC71	viability	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	0.27782087487939394	[439]	[539,518,566,667]	6	hSpCas9	negative selection	9338955
49076424	49076447	X	+	27260156	TC71	viability	TCTCACCCTTGGGGTTGTCCCGG	WDR45	ENSG00000196998	0.3118355832418136	[355]	[595,479,347,471]	7	hSpCas9	negative selection	9338956
49076448	49076471	X	+	27260156	TC71	viability	TATCAAACTCAAACAGCTTTCGG	WDR45	ENSG00000196998	0.17146762644536018	[730]	[836,1043,805,843]	4	hSpCas9	negative selection	9338957
49076739	49076762	X	-	27260156	TC71	viability	CTGCCCAGCAGTGCTGATCTGGG	WDR45	ENSG00000196998	0.293109342867758	[70]	[114,69,108,76]	7	hSpCas9	negative selection	9403203
49077838	49077861	X	+	27260156	TC71	viability	CAGATGCCCCTTCTCCATCAAGG	WDR45	ENSG00000196998	0.24839269447921047	[399]	[472,511,512,541]	6	hSpCas9	negative selection	9403204
49076654	49076677	X	+	27260156	TC32	viability	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	0.4232923041478061	[439]	[494,405,791,599]	7	hSpCas9	negative selection	9460206
49076424	49076447	X	+	27260156	TC32	viability	TCTCACCCTTGGGGTTGTCCCGG	WDR45	ENSG00000196998	0.6014696646521228	[355]	[447,441,557,596]	8	hSpCas9	negative selection	9460207
49076448	49076471	X	+	27260156	TC32	viability	TATCAAACTCAAACAGCTTTCGG	WDR45	ENSG00000196998	0.5950918265101032	[730]	[935,831,1553,940]	8	hSpCas9	negative selection	9460208
49076739	49076762	X	-	27260156	TC32	viability	CTGCCCAGCAGTGCTGATCTGGG	WDR45	ENSG00000196998	-0.9600662130946733	[70]	[24,29,43,40]	-9	hSpCas9	negative selection	9524454
49077838	49077861	X	+	27260156	TC32	viability	CAGATGCCCCTTCTCCATCAAGG	WDR45	ENSG00000196998	-0.029557933896809524	[399]	[409,286,489,305]	0	hSpCas9	negative selection	9524455
49077736	49077759	X	-	27869803	HPAFII	viability after 27 days	TCCCTGTCCAGACCACGAGCAGG	WDR45	ENSG00000196998	0.45478797861522835	[338]	[294,201,NaN]	3	hSpCas9	negative selection	9609010
49077736	49077759	X	-	27869803	HPAFII	viability after 15 days	TCCCTGTCCAGACCACGAGCAGG	WDR45	ENSG00000196998	-0.19192688111072015	[338]	[498,206,NaN]	-2	hSpCas9	negative selection	9691459
49077736	49077759	X	-	27869803	ASPC1	viability after 36 days	TCCCTGTCCAGACCACGAGCAGG	WDR45	ENSG00000196998	-0.7488788595681485	[927]	[69,179,286]	-6	hSpCas9	negative selection	9773908
49077736	49077759	X	-	27869803	PATU8988S	viability after 35 days	TCCCTGTCCAGACCACGAGCAGG	WDR45	ENSG00000196998	0.029925182826051056	[802]	[411,247,NaN]	0	hSpCas9	negative selection	9856357
49077736	49077759	X	-	27869803	PATU8988S	viability after 31 days	TCCCTGTCCAGACCACGAGCAGG	WDR45	ENSG00000196998	0.09102120982753092	[802]	[355,321,NaN]	1	hSpCas9	negative selection	9938806
49077736	49077759	X	-	27869803	HPAFII	viability after 35 days	TCCCTGTCCAGACCACGAGCAGG	WDR45	ENSG00000196998	0.7732989423330395	[338]	[234,358,NaN]	5	hSpCas9	negative selection	10021255
49077736	49077759	X	-	27869803	HPAFII	viability after 31 days	TCCCTGTCCAGACCACGAGCAGG	WDR45	ENSG00000196998	0.502753522081755	[338]	[259,279,NaN]	3	hSpCas9	negative selection	10103704
49075353	49075376	X	+	28162770	P31FUJ	viability	GGGGTACTCACGCGGAGCGGCGG	WDR45	ENSG00000196998	0.5295859866317345	[134]	[228]	6	hSpCas9	negative selection	10264814
49077733	49077756	X	-	28162770	P31FUJ	viability	CTGTCCAGACCACGAGCAGGTGG	WDR45	ENSG00000196998	0.2896188302380649	[549]	[789]	3	hSpCas9	negative selection	10264815
49078061	49078084	X	+	28162770	P31FUJ	viability	AGGCTGGTCACTCCTCGAAGTGG	WDR45	ENSG00000196998	0.5448053742491734	[48]	[83]	6	hSpCas9	negative selection	10264816
49075907	49075930	X	+	28162770	P31FUJ	viability	GCAGTTGCTTCTCCAGGCTGGGG	WDR45	ENSG00000196998	0.8448708499373951	[460]	[972]	8	hSpCas9	negative selection	10264817
49075569	49075592	X	-	28162770	P31FUJ	viability	AAACTGGTGGAGCTGCGCCGAGG	WDR45	ENSG00000196998	0.13643160525134013	[23]	[30]	1	hSpCas9	negative selection	10264818
49076430	49076453	X	-	28162770	P31FUJ	viability	TGATACCCGGGACAACCCCAAGG	WDR45	ENSG00000196998	1.1384536028365522	[45]	[118]	9	hSpCas9	negative selection	10264819
49075619	49075642	X	+	28162770	P31FUJ	viability	AATAAGGGTACCCTTCTGGGAGG	WDR45	ENSG00000196998	0.7519310389323111	[284]	[563]	8	hSpCas9	negative selection	10264820
49077718	49077741	X	-	28162770	P31FUJ	viability	GCAGGTGGGCAGCATGGGCTTGG	WDR45	ENSG00000196998	0.2909193506295651	[392]	[564]	3	hSpCas9	negative selection	10264821
49076654	49076677	X	+	28162770	P31FUJ	viability	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	0.724886990727657	[172]	[335]	8	hSpCas9	negative selection	10264822
49076460	49076483	X	+	28162770	P31FUJ	viability	ACAGCTTTCGGGGATTGTCGGGG	WDR45	ENSG00000196998	0.708570065614913	[225]	[433]	7	hSpCas9	negative selection	10264823
49075353	49075376	X	+	28162770	TF1	viability	GGGGTACTCACGCGGAGCGGCGG	WDR45	ENSG00000196998	NaN	[NaN]	[118]	1	hSpCas9	negative selection	10434180
49077733	49077756	X	-	28162770	TF1	viability	CTGTCCAGACCACGAGCAGGTGG	WDR45	ENSG00000196998	NaN	[NaN]	[606]	1	hSpCas9	negative selection	10434181
49078061	49078084	X	+	28162770	TF1	viability	AGGCTGGTCACTCCTCGAAGTGG	WDR45	ENSG00000196998	NaN	[NaN]	[33]	1	hSpCas9	negative selection	10434182
49075907	49075930	X	+	28162770	TF1	viability	GCAGTTGCTTCTCCAGGCTGGGG	WDR45	ENSG00000196998	NaN	[NaN]	[395]	1	hSpCas9	negative selection	10434183
49075569	49075592	X	-	28162770	TF1	viability	AAACTGGTGGAGCTGCGCCGAGG	WDR45	ENSG00000196998	NaN	[NaN]	[7]	1	hSpCas9	negative selection	10434184
49076430	49076453	X	-	28162770	TF1	viability	TGATACCCGGGACAACCCCAAGG	WDR45	ENSG00000196998	NaN	[NaN]	[5]	1	hSpCas9	negative selection	10434185
49075619	49075642	X	+	28162770	TF1	viability	AATAAGGGTACCCTTCTGGGAGG	WDR45	ENSG00000196998	NaN	[NaN]	[321]	1	hSpCas9	negative selection	10434186
49077718	49077741	X	-	28162770	TF1	viability	GCAGGTGGGCAGCATGGGCTTGG	WDR45	ENSG00000196998	NaN	[NaN]	[327]	1	hSpCas9	negative selection	10434187
49076654	49076677	X	+	28162770	TF1	viability	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	NaN	[NaN]	[256]	1	hSpCas9	negative selection	10434188
49076460	49076483	X	+	28162770	TF1	viability	ACAGCTTTCGGGGATTGTCGGGG	WDR45	ENSG00000196998	NaN	[NaN]	[238]	1	hSpCas9	negative selection	10434189
49075353	49075376	X	+	28162770	SKM1	viability	GGGGTACTCACGCGGAGCGGCGG	WDR45	ENSG00000196998	0.6925714748077528	[34]	[99]	6	hSpCas9	negative selection	10603546
49077733	49077756	X	-	28162770	SKM1	viability	CTGTCCAGACCACGAGCAGGTGG	WDR45	ENSG00000196998	0.5298419747696443	[104]	[267]	5	hSpCas9	negative selection	10603547
49078061	49078084	X	+	28162770	SKM1	viability	AGGCTGGTCACTCCTCGAAGTGG	WDR45	ENSG00000196998	-0.2581008128286788	[22]	[33]	-2	hSpCas9	negative selection	10603548
49075907	49075930	X	+	28162770	SKM1	viability	GCAGTTGCTTCTCCAGGCTGGGG	WDR45	ENSG00000196998	0.34792330342030686	[111]	[251]	3	hSpCas9	negative selection	10603549
49075569	49075592	X	-	28162770	SKM1	viability	AAACTGGTGGAGCTGCGCCGAGG	WDR45	ENSG00000196998	-0.6155508205545792	[12]	[14]	-5	hSpCas9	negative selection	10603550
49076430	49076453	X	-	28162770	SKM1	viability	TGATACCCGGGACAACCCCAAGG	WDR45	ENSG00000196998	-0.385902583215332	[16]	[22]	-3	hSpCas9	negative selection	10603551
49075619	49075642	X	+	28162770	SKM1	viability	AATAAGGGTACCCTTCTGGGAGG	WDR45	ENSG00000196998	0.9779736936700011	[55]	[194]	8	hSpCas9	negative selection	10603552
49077718	49077741	X	-	28162770	SKM1	viability	GCAGGTGGGCAGCATGGGCTTGG	WDR45	ENSG00000196998	-0.08206453732450847	[96]	[161]	0	hSpCas9	negative selection	10603553
49076654	49076677	X	+	28162770	SKM1	viability	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	0.559868937321639	[32]	[85]	5	hSpCas9	negative selection	10603554
49076460	49076483	X	+	28162770	SKM1	viability	ACAGCTTTCGGGGATTGTCGGGG	WDR45	ENSG00000196998	-0.05497886999961944	[56]	[96]	0	hSpCas9	negative selection	10603555
49075353	49075376	X	+	28162770	SKM1	viability	GGGGTACTCACGCGGAGCGGCGG	WDR45	ENSG00000196998	0.6925714748077528	[34]	[99]	6	hSpCas9	negative selection	10772912
49077733	49077756	X	-	28162770	SKM1	viability	CTGTCCAGACCACGAGCAGGTGG	WDR45	ENSG00000196998	0.5298419747696443	[104]	[267]	5	hSpCas9	negative selection	10772913
49078061	49078084	X	+	28162770	SKM1	viability	AGGCTGGTCACTCCTCGAAGTGG	WDR45	ENSG00000196998	-0.2581008128286788	[22]	[33]	-2	hSpCas9	negative selection	10772914
49075907	49075930	X	+	28162770	SKM1	viability	GCAGTTGCTTCTCCAGGCTGGGG	WDR45	ENSG00000196998	0.34792330342030686	[111]	[251]	3	hSpCas9	negative selection	10772915
49075569	49075592	X	-	28162770	SKM1	viability	AAACTGGTGGAGCTGCGCCGAGG	WDR45	ENSG00000196998	-0.6155508205545792	[12]	[14]	-5	hSpCas9	negative selection	10772916
49076430	49076453	X	-	28162770	SKM1	viability	TGATACCCGGGACAACCCCAAGG	WDR45	ENSG00000196998	-0.385902583215332	[16]	[22]	-3	hSpCas9	negative selection	10772917
49075619	49075642	X	+	28162770	SKM1	viability	AATAAGGGTACCCTTCTGGGAGG	WDR45	ENSG00000196998	0.9779736936700011	[55]	[194]	8	hSpCas9	negative selection	10772918
49077718	49077741	X	-	28162770	SKM1	viability	GCAGGTGGGCAGCATGGGCTTGG	WDR45	ENSG00000196998	-0.08206453732450847	[96]	[161]	0	hSpCas9	negative selection	10772919
49076654	49076677	X	+	28162770	SKM1	viability	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	0.559868937321639	[32]	[85]	5	hSpCas9	negative selection	10772920
49076460	49076483	X	+	28162770	SKM1	viability	ACAGCTTTCGGGGATTGTCGGGG	WDR45	ENSG00000196998	-0.05497886999961944	[56]	[96]	0	hSpCas9	negative selection	10772921
49075353	49075376	X	+	28162770	PL21	viability	GGGGTACTCACGCGGAGCGGCGG	WDR45	ENSG00000196998	1.077804071565268	[122]	[112]	8	hSpCas9	negative selection	10942278
49077733	49077756	X	-	28162770	PL21	viability	CTGTCCAGACCACGAGCAGGTGG	WDR45	ENSG00000196998	-0.1611968649562775	[333]	[129]	-1	hSpCas9	negative selection	10942279
49078061	49078084	X	+	28162770	PL21	viability	AGGCTGGTCACTCCTCGAAGTGG	WDR45	ENSG00000196998	-1.9563648711906705	[106]	[11]	-8	hSpCas9	negative selection	10942280
49075907	49075930	X	+	28162770	PL21	viability	GCAGTTGCTTCTCCAGGCTGGGG	WDR45	ENSG00000196998	0.8302820985145964	[481]	[372]	7	hSpCas9	negative selection	10942281
49075569	49075592	X	-	28162770	PL21	viability	AAACTGGTGGAGCTGCGCCGAGG	WDR45	ENSG00000196998	-0.06289479134447395	[23]	[9]	0	hSpCas9	negative selection	10942282
49076430	49076453	X	-	28162770	PL21	viability	TGATACCCGGGACAACCCCAAGG	WDR45	ENSG00000196998	0.8782115196019578	[44]	[35]	7	hSpCas9	negative selection	10942283
49075619	49075642	X	+	28162770	PL21	viability	AATAAGGGTACCCTTCTGGGAGG	WDR45	ENSG00000196998	0.5756487495815263	[221]	[143]	5	hSpCas9	negative selection	10942284
49077718	49077741	X	-	28162770	PL21	viability	GCAGGTGGGCAGCATGGGCTTGG	WDR45	ENSG00000196998	-0.5197524663179447	[279]	[84]	-4	hSpCas9	negative selection	10942285
49076654	49076677	X	+	28162770	PL21	viability	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	1.7851021152104765	[137]	[206]	9	hSpCas9	negative selection	10942286
49076460	49076483	X	+	28162770	PL21	viability	ACAGCTTTCGGGGATTGTCGGGG	WDR45	ENSG00000196998	0.21078685868882857	[134]	[67]	1	hSpCas9	negative selection	10942287
49075353	49075376	X	+	28162770	P31FUJ	viability	GGGGTACTCACGCGGAGCGGCGG	WDR45	ENSG00000196998	0.5295859866317345	[134]	[228]	6	hSpCas9	negative selection	11111644
49077733	49077756	X	-	28162770	P31FUJ	viability	CTGTCCAGACCACGAGCAGGTGG	WDR45	ENSG00000196998	0.2896188302380649	[549]	[789]	3	hSpCas9	negative selection	11111645
49078061	49078084	X	+	28162770	P31FUJ	viability	AGGCTGGTCACTCCTCGAAGTGG	WDR45	ENSG00000196998	0.5448053742491734	[48]	[83]	6	hSpCas9	negative selection	11111646
49075907	49075930	X	+	28162770	P31FUJ	viability	GCAGTTGCTTCTCCAGGCTGGGG	WDR45	ENSG00000196998	0.8448708499373951	[460]	[972]	8	hSpCas9	negative selection	11111647
49075569	49075592	X	-	28162770	P31FUJ	viability	AAACTGGTGGAGCTGCGCCGAGG	WDR45	ENSG00000196998	0.13643160525134013	[23]	[30]	1	hSpCas9	negative selection	11111648
49076430	49076453	X	-	28162770	P31FUJ	viability	TGATACCCGGGACAACCCCAAGG	WDR45	ENSG00000196998	1.1384536028365522	[45]	[118]	9	hSpCas9	negative selection	11111649
49075619	49075642	X	+	28162770	P31FUJ	viability	AATAAGGGTACCCTTCTGGGAGG	WDR45	ENSG00000196998	0.7519310389323111	[284]	[563]	8	hSpCas9	negative selection	11111650
49077718	49077741	X	-	28162770	P31FUJ	viability	GCAGGTGGGCAGCATGGGCTTGG	WDR45	ENSG00000196998	0.2909193506295651	[392]	[564]	3	hSpCas9	negative selection	11111651
49076654	49076677	X	+	28162770	P31FUJ	viability	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	0.724886990727657	[172]	[335]	8	hSpCas9	negative selection	11111652
49076460	49076483	X	+	28162770	P31FUJ	viability	ACAGCTTTCGGGGATTGTCGGGG	WDR45	ENSG00000196998	0.708570065614913	[225]	[433]	7	hSpCas9	negative selection	11111653
49075353	49075376	X	+	28162770	OCIAML5	viability	GGGGTACTCACGCGGAGCGGCGG	WDR45	ENSG00000196998	1.3454706617861751	[45]	[210]	9	hSpCas9	negative selection	11281010
49077733	49077756	X	-	28162770	OCIAML5	viability	CTGTCCAGACCACGAGCAGGTGG	WDR45	ENSG00000196998	0.31566087487406946	[291]	[655]	2	hSpCas9	negative selection	11281011
49078061	49078084	X	+	28162770	OCIAML5	viability	AGGCTGGTCACTCCTCGAAGTGG	WDR45	ENSG00000196998	1.327257128580565	[33]	[153]	9	hSpCas9	negative selection	11281012
49075907	49075930	X	+	28162770	OCIAML5	viability	GCAGTTGCTTCTCCAGGCTGGGG	WDR45	ENSG00000196998	0.7186820706374585	[203]	[605]	6	hSpCas9	negative selection	11281013
49075569	49075592	X	-	28162770	OCIAML5	viability	AAACTGGTGGAGCTGCGCCGAGG	WDR45	ENSG00000196998	0.841830301410323	[16]	[54]	7	hSpCas9	negative selection	11281014
49076430	49076453	X	-	28162770	OCIAML5	viability	TGATACCCGGGACAACCCCAAGG	WDR45	ENSG00000196998	0.2510269221001067	[26]	[57]	2	hSpCas9	negative selection	11281015
49075619	49075642	X	+	28162770	OCIAML5	viability	AATAAGGGTACCCTTCTGGGAGG	WDR45	ENSG00000196998	0.8998255675403121	[124]	[420]	7	hSpCas9	negative selection	11281016
49077718	49077741	X	-	28162770	OCIAML5	viability	GCAGGTGGGCAGCATGGGCTTGG	WDR45	ENSG00000196998	0.885642488941383	[193]	[646]	7	hSpCas9	negative selection	11281017
49076654	49076677	X	+	28162770	OCIAML5	viability	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	0.2901555017884675	[110]	[244]	2	hSpCas9	negative selection	11281018
49076460	49076483	X	+	28162770	OCIAML5	viability	ACAGCTTTCGGGGATTGTCGGGG	WDR45	ENSG00000196998	0.39465517983419157	[125]	[298]	3	hSpCas9	negative selection	11281019
49075353	49075376	X	+	28162770	EOL1	viability	GGGGTACTCACGCGGAGCGGCGG	WDR45	ENSG00000196998	0.3395852708493784	[227]	[151]	3	hSpCas9	negative selection	11450376
49077733	49077756	X	-	28162770	EOL1	viability	CTGTCCAGACCACGAGCAGGTGG	WDR45	ENSG00000196998	0.49235555125262376	[563]	[417]	4	hSpCas9	negative selection	11450377
49078061	49078084	X	+	28162770	EOL1	viability	AGGCTGGTCACTCCTCGAAGTGG	WDR45	ENSG00000196998	0.430438701300492	[99]	[70]	4	hSpCas9	negative selection	11450378
49075907	49075930	X	+	28162770	EOL1	viability	GCAGTTGCTTCTCCAGGCTGGGG	WDR45	ENSG00000196998	0.82614406750954	[727]	[679]	7	hSpCas9	negative selection	11450379
49075569	49075592	X	-	28162770	EOL1	viability	AAACTGGTGGAGCTGCGCCGAGG	WDR45	ENSG00000196998	-0.27339160604137414	[38]	[16]	-2	hSpCas9	negative selection	11450380
49076430	49076453	X	-	28162770	EOL1	viability	TGATACCCGGGACAACCCCAAGG	WDR45	ENSG00000196998	0.7684285696532527	[77]	[69]	6	hSpCas9	negative selection	11450381
49075619	49075642	X	+	28162770	EOL1	viability	AATAAGGGTACCCTTCTGGGAGG	WDR45	ENSG00000196998	0.2995872029174593	[255]	[165]	2	hSpCas9	negative selection	11450382
49077718	49077741	X	-	28162770	EOL1	viability	GCAGGTGGGCAGCATGGGCTTGG	WDR45	ENSG00000196998	0.9449539822323715	[350]	[355]	7	hSpCas9	negative selection	11450383
49076654	49076677	X	+	28162770	EOL1	viability	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	1.114878983674684	[155]	[177]	8	hSpCas9	negative selection	11450384
49076460	49076483	X	+	28162770	EOL1	viability	ACAGCTTTCGGGGATTGTCGGGG	WDR45	ENSG00000196998	0.760767510349131	[204]	[182]	6	hSpCas9	negative selection	11450385
49075353	49075376	X	+	28162770	MOLM13	viability	GGGGTACTCACGCGGAGCGGCGG	WDR45	ENSG00000196998	0.9478823226641927	[189]	[264]	7	hSpCas9	negative selection	11619742
49077733	49077756	X	-	28162770	MOLM13	viability	CTGTCCAGACCACGAGCAGGTGG	WDR45	ENSG00000196998	0.7105010696249847	[414]	[490]	5	hSpCas9	negative selection	11619743
49078061	49078084	X	+	28162770	MOLM13	viability	AGGCTGGTCACTCCTCGAAGTGG	WDR45	ENSG00000196998	-1.9553220491799652	[117]	[21]	-7	hSpCas9	negative selection	11619744
49075907	49075930	X	+	28162770	MOLM13	viability	GCAGTTGCTTCTCCAGGCTGGGG	WDR45	ENSG00000196998	0.9029994834498163	[570]	[771]	7	hSpCas9	negative selection	11619745
49075569	49075592	X	-	28162770	MOLM13	viability	AAACTGGTGGAGCTGCGCCGAGG	WDR45	ENSG00000196998	1.4921369277912557	[58]	[119]	9	hSpCas9	negative selection	11619746
49076430	49076453	X	-	28162770	MOLM13	viability	TGATACCCGGGACAACCCCAAGG	WDR45	ENSG00000196998	0.5467448022558183	[88]	[93]	4	hSpCas9	negative selection	11619747
49075619	49075642	X	+	28162770	MOLM13	viability	AATAAGGGTACCCTTCTGGGAGG	WDR45	ENSG00000196998	-0.291976614731706	[253]	[149]	-2	hSpCas9	negative selection	11619748
49077718	49077741	X	-	28162770	MOLM13	viability	GCAGGTGGGCAGCATGGGCTTGG	WDR45	ENSG00000196998	-0.039797405699939614	[417]	[293]	0	hSpCas9	negative selection	11619749
49076654	49076677	X	+	28162770	MOLM13	viability	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	0.303395343916332	[231]	[206]	2	hSpCas9	negative selection	11619750
49076460	49076483	X	+	28162770	MOLM13	viability	ACAGCTTTCGGGGATTGTCGGGG	WDR45	ENSG00000196998	0.044814563200316876	[239]	[178]	0	hSpCas9	negative selection	11619751
49075353	49075376	X	+	28162770	HEL	viability	GGGGTACTCACGCGGAGCGGCGG	WDR45	ENSG00000196998	0.5070837326427908	[155]	[141]	4	hSpCas9	negative selection	11789108
49077733	49077756	X	-	28162770	HEL	viability	CTGTCCAGACCACGAGCAGGTGG	WDR45	ENSG00000196998	0.31402613254588474	[372]	[296]	2	hSpCas9	negative selection	11789109
49078061	49078084	X	+	28162770	HEL	viability	AGGCTGGTCACTCCTCGAAGTGG	WDR45	ENSG00000196998	0.3030464576371551	[142]	[112]	2	hSpCas9	negative selection	11789110
49075907	49075930	X	+	28162770	HEL	viability	GCAGTTGCTTCTCCAGGCTGGGG	WDR45	ENSG00000196998	0.9010082896654017	[555]	[664]	7	hSpCas9	negative selection	11789111
49075569	49075592	X	-	28162770	HEL	viability	AAACTGGTGGAGCTGCGCCGAGG	WDR45	ENSG00000196998	1.0925417494398773	[40]	[55]	8	hSpCas9	negative selection	11789112
49076430	49076453	X	-	28162770	HEL	viability	TGATACCCGGGACAACCCCAAGG	WDR45	ENSG00000196998	0.3396697643643103	[94]	[76]	3	hSpCas9	negative selection	11789113
49075619	49075642	X	+	28162770	HEL	viability	AATAAGGGTACCCTTCTGGGAGG	WDR45	ENSG00000196998	0.5807519451046559	[213]	[204]	5	hSpCas9	negative selection	11789114
49077718	49077741	X	-	28162770	HEL	viability	GCAGGTGGGCAGCATGGGCTTGG	WDR45	ENSG00000196998	0.05777633127920068	[353]	[235]	0	hSpCas9	negative selection	11789115
49076654	49076677	X	+	28162770	HEL	viability	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	0.22512738905768673	[186]	[139]	1	hSpCas9	negative selection	11789116
49076460	49076483	X	+	28162770	HEL	viability	ACAGCTTTCGGGGATTGTCGGGG	WDR45	ENSG00000196998	1.2865950217750817	[191]	[299]	9	hSpCas9	negative selection	11789117
49075353	49075376	X	+	28162770	MV411	viability	GGGGTACTCACGCGGAGCGGCGG	WDR45	ENSG00000196998	0.8207653510205282	[165]	[246]	7	hSpCas9	negative selection	11958474
49077733	49077756	X	-	28162770	MV411	viability	CTGTCCAGACCACGAGCAGGTGG	WDR45	ENSG00000196998	1.300601084099772	[332]	[690]	9	hSpCas9	negative selection	11958475
49078061	49078084	X	+	28162770	MV411	viability	AGGCTGGTCACTCCTCGAAGTGG	WDR45	ENSG00000196998	0.22047050318250583	[53]	[52]	2	hSpCas9	negative selection	11958476
49075907	49075930	X	+	28162770	MV411	viability	GCAGTTGCTTCTCCAGGCTGGGG	WDR45	ENSG00000196998	1.2056173750881483	[419]	[815]	9	hSpCas9	negative selection	11958477
49075569	49075592	X	-	28162770	MV411	viability	AAACTGGTGGAGCTGCGCCGAGG	WDR45	ENSG00000196998	1.9636445847821842	[13]	[45]	9	hSpCas9	negative selection	11958478
49076430	49076453	X	-	28162770	MV411	viability	TGATACCCGGGACAACCCCAAGG	WDR45	ENSG00000196998	1.6980989597923406	[44]	[122]	9	hSpCas9	negative selection	11958479
49075619	49075642	X	+	28162770	MV411	viability	AATAAGGGTACCCTTCTGGGAGG	WDR45	ENSG00000196998	1.313526741240548	[191]	[401]	9	hSpCas9	negative selection	11958480
49077718	49077741	X	-	28162770	MV411	viability	GCAGGTGGGCAGCATGGGCTTGG	WDR45	ENSG00000196998	0.35824433666870986	[237]	[256]	3	hSpCas9	negative selection	11958481
49076654	49076677	X	+	28162770	MV411	viability	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	1.1869729095188808	[133]	[256]	9	hSpCas9	negative selection	11958482
49076460	49076483	X	+	28162770	MV411	viability	ACAGCTTTCGGGGATTGTCGGGG	WDR45	ENSG00000196998	0.4066361456320293	[179]	[200]	3	hSpCas9	negative selection	11958483
49075353	49075376	X	+	28162770	MONOMAC1	viability	GGGGTACTCACGCGGAGCGGCGG	WDR45	ENSG00000196998	0.4151471223966269	[69]	[106]	4	hSpCas9	negative selection	12127840
49077733	49077756	X	-	28162770	MONOMAC1	viability	CTGTCCAGACCACGAGCAGGTGG	WDR45	ENSG00000196998	1.1566001075551466	[215]	[551]	8	hSpCas9	negative selection	12127841
49078061	49078084	X	+	28162770	MONOMAC1	viability	AGGCTGGTCACTCCTCGAAGTGG	WDR45	ENSG00000196998	1.0335760810818626	[74]	[175]	8	hSpCas9	negative selection	12127842
49075907	49075930	X	+	28162770	MONOMAC1	viability	GCAGTTGCTTCTCCAGGCTGGGG	WDR45	ENSG00000196998	1.6015832650204418	[283]	[987]	9	hSpCas9	negative selection	12127843
49075569	49075592	X	-	28162770	MONOMAC1	viability	AAACTGGTGGAGCTGCGCCGAGG	WDR45	ENSG00000196998	-1.518964941946916	[24]	[9]	-8	hSpCas9	negative selection	12127844
49076430	49076453	X	-	28162770	MONOMAC1	viability	TGATACCCGGGACAACCCCAAGG	WDR45	ENSG00000196998	1.4888545625123835	[22]	[73]	9	hSpCas9	negative selection	12127845
49075619	49075642	X	+	28162770	MONOMAC1	viability	AATAAGGGTACCCTTCTGGGAGG	WDR45	ENSG00000196998	0.6405326880450583	[107]	[192]	6	hSpCas9	negative selection	12127846
49077718	49077741	X	-	28162770	MONOMAC1	viability	GCAGGTGGGCAGCATGGGCTTGG	WDR45	ENSG00000196998	0.11404968818038175	[186]	[231]	1	hSpCas9	negative selection	12127847
49076654	49076677	X	+	28162770	MONOMAC1	viability	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	0.41177239561597034	[79]	[121]	4	hSpCas9	negative selection	12127848
49076460	49076483	X	+	28162770	MONOMAC1	viability	ACAGCTTTCGGGGATTGTCGGGG	WDR45	ENSG00000196998	0.9518265388549292	[91]	[203]	8	hSpCas9	negative selection	12127849
49075353	49075376	X	+	28162770	OCIAML2	viability	GGGGTACTCACGCGGAGCGGCGG	WDR45	ENSG00000196998	0.8147723936200872	[27]	[272]	7	hSpCas9	negative selection	12297206
49077733	49077756	X	-	28162770	OCIAML2	viability	CTGTCCAGACCACGAGCAGGTGG	WDR45	ENSG00000196998	0.3891925167095782	[80]	[587]	4	hSpCas9	negative selection	12297207
49078061	49078084	X	+	28162770	OCIAML2	viability	AGGCTGGTCACTCCTCGAAGTGG	WDR45	ENSG00000196998	1.39444059467173	[6]	[101]	9	hSpCas9	negative selection	12297208
49075907	49075930	X	+	28162770	OCIAML2	viability	GCAGTTGCTTCTCCAGGCTGGGG	WDR45	ENSG00000196998	1.3015197655423814	[79]	[1092]	9	hSpCas9	negative selection	12297209
49075569	49075592	X	-	28162770	OCIAML2	viability	AAACTGGTGGAGCTGCGCCGAGG	WDR45	ENSG00000196998	0.8147723936200872	[3]	[38]	7	hSpCas9	negative selection	12297210
49076430	49076453	X	-	28162770	OCIAML2	viability	TGATACCCGGGACAACCCCAAGG	WDR45	ENSG00000196998	-0.09559039389523649	[15]	[82]	-1	hSpCas9	negative selection	12297211
49075619	49075642	X	+	28162770	OCIAML2	viability	AATAAGGGTACCCTTCTGGGAGG	WDR45	ENSG00000196998	0.2420882226773677	[35]	[235]	2	hSpCas9	negative selection	12297212
49077718	49077741	X	-	28162770	OCIAML2	viability	GCAGGTGGGCAGCATGGGCTTGG	WDR45	ENSG00000196998	0.7414206518728275	[44]	[416]	7	hSpCas9	negative selection	12297213
49076654	49076677	X	+	28162770	OCIAML2	viability	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	0.3808476500477507	[22]	[165]	3	hSpCas9	negative selection	12297214
49076460	49076483	X	+	28162770	OCIAML2	viability	ACAGCTTTCGGGGATTGTCGGGG	WDR45	ENSG00000196998	1.2420882226773675	[26]	[353]	9	hSpCas9	negative selection	12297215
49075353	49075376	X	+	28162770	OCIAML3	viability	GGGGTACTCACGCGGAGCGGCGG	WDR45	ENSG00000196998	0.3248555969504313	[31]	[120]	3	hSpCas9	negative selection	12466572
49077733	49077756	X	-	28162770	OCIAML3	viability	CTGTCCAGACCACGAGCAGGTGG	WDR45	ENSG00000196998	0.4089948478373604	[119]	[480]	4	hSpCas9	negative selection	12466573
49078061	49078084	X	+	28162770	OCIAML3	viability	AGGCTGGTCACTCCTCGAAGTGG	WDR45	ENSG00000196998	-1.9159357352115254	[19]	[15]	-8	hSpCas9	negative selection	12466574
49075907	49075930	X	+	28162770	OCIAML3	viability	GCAGTTGCTTCTCCAGGCTGGGG	WDR45	ENSG00000196998	0.036235739697859204	[114]	[355]	0	hSpCas9	negative selection	12466575
49075569	49075592	X	-	28162770	OCIAML3	viability	AAACTGGTGGAGCTGCGCCGAGG	WDR45	ENSG00000196998	-3.2944473584652556	[12]	[3]	-9	hSpCas9	negative selection	12466576
49076430	49076453	X	-	28162770	OCIAML3	viability	TGATACCCGGGACAACCCCAAGG	WDR45	ENSG00000196998	0.0840642647884744	[9]	[31]	0	hSpCas9	negative selection	12466577
49075619	49075642	X	+	28162770	OCIAML3	viability	AATAAGGGTACCCTTCTGGGAGG	WDR45	ENSG00000196998	0.7815014947680432	[73]	[383]	7	hSpCas9	negative selection	12466578
49077718	49077741	X	-	28162770	OCIAML3	viability	GCAGGTGGGCAGCATGGGCTTGG	WDR45	ENSG00000196998	0.16465302494136203	[98]	[334]	1	hSpCas9	negative selection	12466579
49076654	49076677	X	+	28162770	OCIAML3	viability	CGCATGCGCACAGAAAGCACTGG	WDR45	ENSG00000196998	-0.28467958221643436	[45]	[113]	-2	hSpCas9	negative selection	12466580
49076460	49076483	X	+	28162770	OCIAML3	viability	ACAGCTTTCGGGGATTGTCGGGG	WDR45	ENSG00000196998	0.632060439155683	[55]	[261]	6	hSpCas9	negative selection	12466581