Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 7466
• Symbol: WFS1
• Description: wolframin ER transmembrane glycoprotein

DataSource: http://genomecrispr.dkfz.de/#!/results/WFS1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
6289082	6289105	4	-	26472758	Jiyoye	viability	GCAGCTTCACAGCCTCGCGACGG	WFS1	ENSG00000109501	5.7647273861239565	[0]	[40]	9	hSpCas9	negative selection	181834
6277666	6277689	4	+	26472758	Jiyoye	viability	CGGGAAAGAGCAGACGGCACCGG	WFS1	ENSG00000109501	-0.1326992296867447	[188]	[129]	-1	hSpCas9	negative selection	181835
6289045	6289068	4	-	26472758	Jiyoye	viability	GAGGACCAGCCAGTCCACAGCGG	WFS1	ENSG00000109501	0.47276372313345016	[85]	[89]	3	hSpCas9	negative selection	181836
6291201	6291224	4	+	26472758	Jiyoye	viability	CACGTCCGAGAACGAACGGGAGG	WFS1	ENSG00000109501	-0.00786211777297019	[67]	[50]	0	hSpCas9	negative selection	181837
6291306	6291329	4	+	26472758	Jiyoye	viability	GAAGAAGAAGCAGGTGGCCGTGG	WFS1	ENSG00000109501	0.598871005619405	[189]	[216]	4	hSpCas9	negative selection	181838
6295075	6295098	4	+	26472758	Jiyoye	viability	GATCACTAAGAAGTACGCCAAGG	WFS1	ENSG00000109501	1.6601561226757444	[59]	[142]	8	hSpCas9	negative selection	181839
6277632	6277655	4	-	26472758	Jiyoye	viability	GCTGGGCCTGGGGTTCAGCGGGG	WFS1	ENSG00000109501	-0.20949597894262073	[68]	[44]	-1	hSpCas9	negative selection	181840
6291323	6291346	4	-	26472758	Jiyoye	viability	ATTCTCCAGCAGCTCCGCCACGG	WFS1	ENSG00000109501	-0.19916077000784976	[101]	[66]	-1	hSpCas9	negative selection	181841
6291944	6291967	4	+	26472758	Jiyoye	viability	CCAAGTCCCTGCAGAAGCAGAGG	WFS1	ENSG00000109501	-0.37043219715767894	[35]	[20]	-3	hSpCas9	negative selection	181842
6295175	6295198	4	-	26472758	Jiyoye	viability	TCACTCACCTTCAGACGCAGTGG	WFS1	ENSG00000109501	0.9287125020853958	[61]	[88]	6	hSpCas9	negative selection	181843
6289082	6289105	4	-	26472758	KBM7	viability	GCAGCTTCACAGCCTCGCGACGG	WFS1	ENSG00000109501	-0.6064025420387074	[100,84]	[35,21]	-5	hSpCas9	negative selection	372952
6277666	6277689	4	+	26472758	KBM7	viability	CGGGAAAGAGCAGACGGCACCGG	WFS1	ENSG00000109501	0.663151510580487	[585,659]	[422,509]	7	hSpCas9	negative selection	372953
6289045	6289068	4	-	26472758	KBM7	viability	GAGGACCAGCCAGTCCACAGCGG	WFS1	ENSG00000109501	0.026903355299811693	[394,229]	[157,135]	0	hSpCas9	negative selection	372954
6291201	6291224	4	+	26472758	KBM7	viability	CACGTCCGAGAACGAACGGGAGG	WFS1	ENSG00000109501	-0.045905059265808124	[282,307]	[157,115]	0	hSpCas9	negative selection	372955
6291306	6291329	4	+	26472758	KBM7	viability	GAAGAAGAAGCAGGTGGCCGTGG	WFS1	ENSG00000109501	0.5862449265722575	[599,393]	[361,329]	6	hSpCas9	negative selection	372956
6295075	6295098	4	+	26472758	KBM7	viability	GATCACTAAGAAGTACGCCAAGG	WFS1	ENSG00000109501	0.6030684241792281	[481,476]	[448,249]	6	hSpCas9	negative selection	372957
6277632	6277655	4	-	26472758	KBM7	viability	GCTGGGCCTGGGGTTCAGCGGGG	WFS1	ENSG00000109501	1.1036191599347598	[203,192]	[125,267]	9	hSpCas9	negative selection	372958
6291323	6291346	4	-	26472758	KBM7	viability	ATTCTCCAGCAGCTCCGCCACGG	WFS1	ENSG00000109501	0.24505873773953996	[349,232]	[76,233]	2	hSpCas9	negative selection	372959
6291944	6291967	4	+	26472758	KBM7	viability	CCAAGTCCCTGCAGAAGCAGAGG	WFS1	ENSG00000109501	0.30171392211601056	[190,177]	[86,124]	3	hSpCas9	negative selection	372960
6295175	6295198	4	-	26472758	KBM7	viability	TCACTCACCTTCAGACGCAGTGG	WFS1	ENSG00000109501	0.85228972594302	[260,427]	[402,209]	8	hSpCas9	negative selection	372961
6289082	6289105	4	-	26472758	Raji	viability	GCAGCTTCACAGCCTCGCGACGG	WFS1	ENSG00000109501	1.3524960332101308	[26]	[15]	9	hSpCas9	negative selection	564070
6277666	6277689	4	+	26472758	Raji	viability	CGGGAAAGAGCAGACGGCACCGG	WFS1	ENSG00000109501	0.11772547959505836	[277]	[69]	1	hSpCas9	negative selection	564071
6289045	6289068	4	-	26472758	Raji	viability	GAGGACCAGCCAGTCCACAGCGG	WFS1	ENSG00000109501	0.30442038243315306	[163]	[46]	3	hSpCas9	negative selection	564072
6291201	6291224	4	+	26472758	Raji	viability	CACGTCCGAGAACGAACGGGAGG	WFS1	ENSG00000109501	1.354693588914377	[122]	[72]	9	hSpCas9	negative selection	564073
6291306	6291329	4	+	26472758	Raji	viability	GAAGAAGAAGCAGGTGGCCGTGG	WFS1	ENSG00000109501	1.198148999296782	[153]	[81]	9	hSpCas9	negative selection	564074
6295075	6295098	4	+	26472758	Raji	viability	GATCACTAAGAAGTACGCCAAGG	WFS1	ENSG00000109501	0.629734058795077	[258]	[92]	6	hSpCas9	negative selection	564075
6277632	6277655	4	-	26472758	Raji	viability	GCTGGGCCTGGGGTTCAGCGGGG	WFS1	ENSG00000109501	-0.10984718084706957	[92]	[19]	-1	hSpCas9	negative selection	564076
6291323	6291346	4	-	26472758	Raji	viability	ATTCTCCAGCAGCTCCGCCACGG	WFS1	ENSG00000109501	0.6048831948444162	[169]	[59]	6	hSpCas9	negative selection	564077
6291944	6291967	4	+	26472758	Raji	viability	CCAAGTCCCTGCAGAAGCAGAGG	WFS1	ENSG00000109501	0.32977595671004734	[119]	[34]	3	hSpCas9	negative selection	564078
6295175	6295198	4	-	26472758	Raji	viability	TCACTCACCTTCAGACGCAGTGG	WFS1	ENSG00000109501	0.7040278411423909	[163]	[61]	6	hSpCas9	negative selection	564079
6289082	6289105	4	-	26472758	K562	viability	GCAGCTTCACAGCCTCGCGACGG	WFS1	ENSG00000109501	-0.11598351503555104	[94]	[73]	-1	hSpCas9	negative selection	755188
6277666	6277689	4	+	26472758	K562	viability	CGGGAAAGAGCAGACGGCACCGG	WFS1	ENSG00000109501	0.422894032472688	[485]	[549]	3	hSpCas9	negative selection	755189
6289045	6289068	4	-	26472758	K562	viability	GAGGACCAGCCAGTCCACAGCGG	WFS1	ENSG00000109501	0.775543076760053	[181]	[262]	6	hSpCas9	negative selection	755190
6291201	6291224	4	+	26472758	K562	viability	CACGTCCGAGAACGAACGGGAGG	WFS1	ENSG00000109501	-0.06956686561410252	[316]	[254]	0	hSpCas9	negative selection	755191
6291306	6291329	4	+	26472758	K562	viability	GAAGAAGAAGCAGGTGGCCGTGG	WFS1	ENSG00000109501	-0.43130923697789153	[368]	[230]	-3	hSpCas9	negative selection	755192
6295075	6295098	4	+	26472758	K562	viability	GATCACTAAGAAGTACGCCAAGG	WFS1	ENSG00000109501	0.2683219141929334	[418]	[425]	2	hSpCas9	negative selection	755193
6277632	6277655	4	-	26472758	K562	viability	GCTGGGCCTGGGGTTCAGCGGGG	WFS1	ENSG00000109501	0.36747712407078503	[145]	[158]	3	hSpCas9	negative selection	755194
6291323	6291346	4	-	26472758	K562	viability	ATTCTCCAGCAGCTCCGCCACGG	WFS1	ENSG00000109501	1.5839051939381137	[146]	[371]	9	hSpCas9	negative selection	755195
6291944	6291967	4	+	26472758	K562	viability	CCAAGTCCCTGCAGAAGCAGAGG	WFS1	ENSG00000109501	-0.28609598903233313	[155]	[107]	-2	hSpCas9	negative selection	755196
6295175	6295198	4	-	26472758	K562	viability	TCACTCACCTTCAGACGCAGTGG	WFS1	ENSG00000109501	0.4240123773467926	[346]	[392]	3	hSpCas9	negative selection	755197
6277609	6277632	4	-	26627737	DLD1	viability	GCCGCTGCGTCTCTAACACCAGG	WFS1	ENSG00000109501	-0.24117567576140103	[358]	[39,248,14]	-3	hSpCas9	negative selection	825503
6287120	6287143	4	+	26627737	DLD1	viability	CCTTTGAAGAAGTCCTGGAGAGG	WFS1	ENSG00000109501	0.7589058069565571	[292]	[162,148,152]	7	hSpCas9	negative selection	825505
6289109	6289132	4	-	26627737	DLD1	viability	CTCTTCTGTCCGCCAAGCACCGG	WFS1	ENSG00000109501	0.31702705747685966	[983]	[437,447,281]	3	hSpCas9	negative selection	825506
6291323	6291346	4	-	26627737	DLD1	viability	ATTCTCCAGCAGCTCCGCCACGG	WFS1	ENSG00000109501	0.6396738155029751	[320]	[85,239,147]	6	hSpCas9	negative selection	825507
6291981	6292004	4	-	26627737	DLD1	viability	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	0.7940298803776854	[481]	[121,236,401]	7	hSpCas9	negative selection	825508
6295039	6295062	4	+	26627737	DLD1	viability	AGCCAAGAACTACATCGCGCTGG	WFS1	ENSG00000109501	-0.20508786308537852	[1050]	[322,336,208]	-2	hSpCas9	negative selection	825509
6277609	6277632	4	-	26627737	GBM cells	viability after 5 days	GCCGCTGCGTCTCTAACACCAGG	WFS1	ENSG00000109501	0.5477485587732267	[80]	[79,46]	7	hSpCas9	negative selection	907818
6287120	6287143	4	+	26627737	GBM cells	viability after 5 days	CCTTTGAAGAAGTCCTGGAGAGG	WFS1	ENSG00000109501	0.05829649869633324	[350]	[168,222]	0	hSpCas9	negative selection	907820
6289109	6289132	4	-	26627737	GBM cells	viability after 5 days	CTCTTCTGTCCGCCAAGCACCGG	WFS1	ENSG00000109501	-0.013925324070435341	[561]	[338,257]	0	hSpCas9	negative selection	907821
6291323	6291346	4	-	26627737	GBM cells	viability after 5 days	ATTCTCCAGCAGCTCCGCCACGG	WFS1	ENSG00000109501	0.7477961420335576	[180]	[185,139]	8	hSpCas9	negative selection	907822
6291981	6292004	4	-	26627737	GBM cells	viability after 5 days	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	0.20801792941546463	[225]	[174,104]	3	hSpCas9	negative selection	907823
6295039	6295062	4	+	26627737	GBM cells	viability after 5 days	AGCCAAGAACTACATCGCGCTGG	WFS1	ENSG00000109501	0.18213844044256386	[271]	[205,124]	3	hSpCas9	negative selection	907824
6277609	6277632	4	-	26627737	GBM cells	viability after 13 days	GCCGCTGCGTCTCTAACACCAGG	WFS1	ENSG00000109501	0.32919535585297166	[80]	[68,43]	4	hSpCas9	negative selection	990133
6287120	6287143	4	+	26627737	GBM cells	viability after 13 days	CCTTTGAAGAAGTCCTGGAGAGG	WFS1	ENSG00000109501	0.0818330336848464	[350]	[216,188]	1	hSpCas9	negative selection	990135
6289109	6289132	4	-	26627737	GBM cells	viability after 13 days	CTCTTCTGTCCGCCAAGCACCGG	WFS1	ENSG00000109501	0.09949295383069123	[561]	[345,310]	1	hSpCas9	negative selection	990136
6291323	6291346	4	-	26627737	GBM cells	viability after 13 days	ATTCTCCAGCAGCTCCGCCACGG	WFS1	ENSG00000109501	0.5517401680579229	[180]	[122,160]	7	hSpCas9	negative selection	990137
6291981	6292004	4	-	26627737	GBM cells	viability after 13 days	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	0.23243837847689858	[225]	[121,161]	3	hSpCas9	negative selection	990138
6295039	6295062	4	+	26627737	GBM cells	viability after 13 days	AGCCAAGAACTACATCGCGCTGG	WFS1	ENSG00000109501	0.47220448626591327	[271]	[287,136]	6	hSpCas9	negative selection	990139
6277609	6277632	4	-	26627737	GBM cells	viability after 21 days	GCCGCTGCGTCTCTAACACCAGG	WFS1	ENSG00000109501	0.9505283860698546	[80]	[83,85]	8	hSpCas9	negative selection	1072448
6287120	6287143	4	+	26627737	GBM cells	viability after 21 days	CCTTTGAAGAAGTCCTGGAGAGG	WFS1	ENSG00000109501	0.24274248523702457	[350]	[245,206]	2	hSpCas9	negative selection	1072450
6289109	6289132	4	-	26627737	GBM cells	viability after 21 days	CTCTTCTGTCCGCCAAGCACCGG	WFS1	ENSG00000109501	-0.058287719509964475	[561]	[322,265]	0	hSpCas9	negative selection	1072451
6291323	6291346	4	-	26627737	GBM cells	viability after 21 days	ATTCTCCAGCAGCTCCGCCACGG	WFS1	ENSG00000109501	0.44360270753611525	[180]	[139,127]	4	hSpCas9	negative selection	1072452
6291981	6292004	4	-	26627737	GBM cells	viability after 21 days	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	-0.011049000832404787	[225]	[148,96]	0	hSpCas9	negative selection	1072453
6295039	6295062	4	+	26627737	GBM cells	viability after 21 days	AGCCAAGAACTACATCGCGCTGG	WFS1	ENSG00000109501	-0.10884648067926184	[271]	[147,126]	-1	hSpCas9	negative selection	1072454
6277609	6277632	4	-	26627737	RPE1	viability after 9 days	GCCGCTGCGTCTCTAACACCAGG	WFS1	ENSG00000109501	0.6853759704154746	[258]	[139,117]	4	hSpCas9	negative selection	1154763
6287120	6287143	4	+	26627737	RPE1	viability after 9 days	CCTTTGAAGAAGTCCTGGAGAGG	WFS1	ENSG00000109501	0.7199342275883256	[782]	[346,476]	5	hSpCas9	negative selection	1154765
6289109	6289132	4	-	26627737	RPE1	viability after 9 days	CTCTTCTGTCCGCCAAGCACCGG	WFS1	ENSG00000109501	1.3787597898162602	[794]	[572,742]	7	hSpCas9	negative selection	1154766
6291323	6291346	4	-	26627737	RPE1	viability after 9 days	ATTCTCCAGCAGCTCCGCCACGG	WFS1	ENSG00000109501	-1.9480377991941862	[1600]	[204,32]	-8	hSpCas9	negative selection	1154767
6291981	6292004	4	-	26627737	RPE1	viability after 9 days	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	0.18504966744731688	[977]	[420,253]	1	hSpCas9	negative selection	1154768
6295039	6295062	4	+	26627737	RPE1	viability after 9 days	AGCCAAGAACTACATCGCGCTGG	WFS1	ENSG00000109501	0.5839690968086106	[739]	[324,375]	4	hSpCas9	negative selection	1154769
6277609	6277632	4	-	26627737	RPE1	viability after 12 days	GCCGCTGCGTCTCTAACACCAGG	WFS1	ENSG00000109501	0.6448378703495607	[258]	[135,79]	4	hSpCas9	negative selection	1237078
6287120	6287143	4	+	26627737	RPE1	viability after 12 days	CCTTTGAAGAAGTCCTGGAGAGG	WFS1	ENSG00000109501	0.7067490544563931	[782]	[303,384]	4	hSpCas9	negative selection	1237080
6289109	6289132	4	-	26627737	RPE1	viability after 12 days	CTCTTCTGTCCGCCAAGCACCGG	WFS1	ENSG00000109501	1.1647518731431676	[794]	[507,447]	7	hSpCas9	negative selection	1237081
6291323	6291346	4	-	26627737	RPE1	viability after 12 days	ATTCTCCAGCAGCTCCGCCACGG	WFS1	ENSG00000109501	-1.8061316755038792	[1600]	[190,50]	-8	hSpCas9	negative selection	1237082
6291981	6292004	4	-	26627737	RPE1	viability after 12 days	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	-0.5583764037287425	[977]	[124,234]	-4	hSpCas9	negative selection	1237083
6295039	6295062	4	+	26627737	RPE1	viability after 12 days	AGCCAAGAACTACATCGCGCTGG	WFS1	ENSG00000109501	-0.4108548567401061	[739]	[184,111]	-3	hSpCas9	negative selection	1237084
6277609	6277632	4	-	26627737	RPE1	viability after 15 days	GCCGCTGCGTCTCTAACACCAGG	WFS1	ENSG00000109501	0.7515095064858951	[258]	[131,114]	4	hSpCas9	negative selection	1319393
6287120	6287143	4	+	26627737	RPE1	viability after 15 days	CCTTTGAAGAAGTCCTGGAGAGG	WFS1	ENSG00000109501	0.5983973551786587	[782]	[371,299]	4	hSpCas9	negative selection	1319395
6289109	6289132	4	-	26627737	RPE1	viability after 15 days	CTCTTCTGTCCGCCAAGCACCGG	WFS1	ENSG00000109501	1.9407406907314095	[794]	[927,800]	8	hSpCas9	negative selection	1319396
6291323	6291346	4	-	26627737	RPE1	viability after 15 days	ATTCTCCAGCAGCTCCGCCACGG	WFS1	ENSG00000109501	-1.8738488264920234	[1600]	[175,72]	-8	hSpCas9	negative selection	1319397
6291981	6292004	4	-	26627737	RPE1	viability after 15 days	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	0.13501908809132274	[977]	[483,129]	0	hSpCas9	negative selection	1319398
6295039	6295062	4	+	26627737	RPE1	viability after 15 days	AGCCAAGAACTACATCGCGCTGG	WFS1	ENSG00000109501	0.5730994574024978	[739]	[371,252]	3	hSpCas9	negative selection	1319399
6277609	6277632	4	-	26627737	RPE1	viability after 18 days	GCCGCTGCGTCTCTAACACCAGG	WFS1	ENSG00000109501	0.5002123211141314	[258]	[123,71]	3	hSpCas9	negative selection	1401708
6287120	6287143	4	+	26627737	RPE1	viability after 18 days	CCTTTGAAGAAGTCCTGGAGAGG	WFS1	ENSG00000109501	0.8916491393048136	[782]	[363,421]	5	hSpCas9	negative selection	1401710
6289109	6289132	4	-	26627737	RPE1	viability after 18 days	CTCTTCTGTCCGCCAAGCACCGG	WFS1	ENSG00000109501	1.5179873186242692	[794]	[568,662]	7	hSpCas9	negative selection	1401711
6291323	6291346	4	-	26627737	RPE1	viability after 18 days	ATTCTCCAGCAGCTCCGCCACGG	WFS1	ENSG00000109501	-1.4987744246358565	[1600]	[236,62]	-7	hSpCas9	negative selection	1401712
6291981	6292004	4	-	26627737	RPE1	viability after 18 days	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	0.5176772751248561	[977]	[329,428]	3	hSpCas9	negative selection	1401713
6295039	6295062	4	+	26627737	RPE1	viability after 18 days	AGCCAAGAACTACATCGCGCTGG	WFS1	ENSG00000109501	0.36720656996205336	[739]	[332,176]	2	hSpCas9	negative selection	1401714
6277609	6277632	4	-	26627737	HeLa	viability after 8 days	GCCGCTGCGTCTCTAACACCAGG	WFS1	ENSG00000109501	1.036903106636253	[188]	[157,356,0]	7	hSpCas9	negative selection	1484023
6287120	6287143	4	+	26627737	HeLa	viability after 8 days	CCTTTGAAGAAGTCCTGGAGAGG	WFS1	ENSG00000109501	0.3405248538445444	[430]	[310,200,217]	3	hSpCas9	negative selection	1484025
6289109	6289132	4	-	26627737	HeLa	viability after 8 days	CTCTTCTGTCCGCCAAGCACCGG	WFS1	ENSG00000109501	-0.9632081595250546	[1009]	[393,221,105]	-7	hSpCas9	negative selection	1484026
6291323	6291346	4	-	26627737	HeLa	viability after 8 days	ATTCTCCAGCAGCTCCGCCACGG	WFS1	ENSG00000109501	0.47282970031675386	[196]	[181,87,101]	4	hSpCas9	negative selection	1484027
6291981	6292004	4	-	26627737	HeLa	viability after 8 days	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	2.1524623806404284	[106]	[208,124,281]	9	hSpCas9	negative selection	1484028
6295039	6295062	4	+	26627737	HeLa	viability after 8 days	AGCCAAGAACTACATCGCGCTGG	WFS1	ENSG00000109501	0.5115206633570516	[442]	[318,208,303]	4	hSpCas9	negative selection	1484029
6277609	6277632	4	-	26627737	HeLa	viability after 12 days	GCCGCTGCGTCTCTAACACCAGG	WFS1	ENSG00000109501	-0.1257169525834947	[188]	[40,60,112]	-1	hSpCas9	negative selection	1566338
6287120	6287143	4	+	26627737	HeLa	viability after 12 days	CCTTTGAAGAAGTCCTGGAGAGG	WFS1	ENSG00000109501	0.06218011394632528	[430]	[153,194,206]	0	hSpCas9	negative selection	1566340
6289109	6289132	4	-	26627737	HeLa	viability after 12 days	CTCTTCTGTCCGCCAAGCACCGG	WFS1	ENSG00000109501	-0.7804460646148972	[1009]	[222,180,330]	-6	hSpCas9	negative selection	1566341
6291323	6291346	4	-	26627737	HeLa	viability after 12 days	ATTCTCCAGCAGCTCCGCCACGG	WFS1	ENSG00000109501	0.7504115048783375	[196]	[133,134,141]	6	hSpCas9	negative selection	1566342
6291981	6292004	4	-	26627737	HeLa	viability after 12 days	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	2.623860177132295	[106]	[195,210,414]	9	hSpCas9	negative selection	1566343
6295039	6295062	4	+	26627737	HeLa	viability after 12 days	AGCCAAGAACTACATCGCGCTGG	WFS1	ENSG00000109501	0.3926398923529484	[442]	[265,190,269]	3	hSpCas9	negative selection	1566344
6277609	6277632	4	-	26627737	HeLa	viability after 15 days	GCCGCTGCGTCTCTAACACCAGG	WFS1	ENSG00000109501	0.6422778433748662	[188]	[96,89,177]	5	hSpCas9	negative selection	1648653
6287120	6287143	4	+	26627737	HeLa	viability after 15 days	CCTTTGAAGAAGTCCTGGAGAGG	WFS1	ENSG00000109501	0.05662088934792023	[430]	[186,230,124]	0	hSpCas9	negative selection	1648655
6289109	6289132	4	-	26627737	HeLa	viability after 15 days	CTCTTCTGTCCGCCAAGCACCGG	WFS1	ENSG00000109501	-0.21167260073384986	[1009]	[358,388,313]	-2	hSpCas9	negative selection	1648656
6291323	6291346	4	-	26627737	HeLa	viability after 15 days	ATTCTCCAGCAGCTCCGCCACGG	WFS1	ENSG00000109501	0.753604322544246	[196]	[123,131,150]	6	hSpCas9	negative selection	1648657
6291981	6292004	4	-	26627737	HeLa	viability after 15 days	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	2.511060455132741	[106]	[94,172,497]	9	hSpCas9	negative selection	1648658
6295039	6295062	4	+	26627737	HeLa	viability after 15 days	AGCCAAGAACTACATCGCGCTGG	WFS1	ENSG00000109501	-0.18777579730771884	[442]	[127,205,139]	-1	hSpCas9	negative selection	1648659
6277609	6277632	4	-	26627737	HeLa	viability after 18 days	GCCGCTGCGTCTCTAACACCAGG	WFS1	ENSG00000109501	0.6914457273576566	[188]	[71,75,177]	5	hSpCas9	negative selection	1730968
6287120	6287143	4	+	26627737	HeLa	viability after 18 days	CCTTTGAAGAAGTCCTGGAGAGG	WFS1	ENSG00000109501	-0.0018141457388600457	[430]	[121,177,124]	0	hSpCas9	negative selection	1730970
6289109	6289132	4	-	26627737	HeLa	viability after 18 days	CTCTTCTGTCCGCCAAGCACCGG	WFS1	ENSG00000109501	-0.21618945894880115	[1009]	[241,317,313]	-2	hSpCas9	negative selection	1730971
6291323	6291346	4	-	26627737	HeLa	viability after 18 days	ATTCTCCAGCAGCTCCGCCACGG	WFS1	ENSG00000109501	0.7133375247059471	[196]	[76,107,150]	5	hSpCas9	negative selection	1730972
6291981	6292004	4	-	26627737	HeLa	viability after 18 days	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	2.5219495165274193	[106]	[69,139,497]	9	hSpCas9	negative selection	1730973
6295039	6295062	4	+	26627737	HeLa	viability after 18 days	AGCCAAGAACTACATCGCGCTGG	WFS1	ENSG00000109501	-0.20731177122419087	[442]	[82,168,139]	-2	hSpCas9	negative selection	1730974
6277609	6277632	4	-	26627737	HCT116	viability after 6 days	GCCGCTGCGTCTCTAACACCAGG	WFS1	ENSG00000109501	-0.37934509689300056	[412]	[27,61]	-2	hSpCas9	negative selection	1813283
6287120	6287143	4	+	26627737	HCT116	viability after 6 days	CCTTTGAAGAAGTCCTGGAGAGG	WFS1	ENSG00000109501	1.733736407171426	[611]	[134,421]	8	hSpCas9	negative selection	1813285
6289109	6289132	4	-	26627737	HCT116	viability after 6 days	CTCTTCTGTCCGCCAAGCACCGG	WFS1	ENSG00000109501	-0.6465507262745286	[1159]	[227,54]	-4	hSpCas9	negative selection	1813286
6291323	6291346	4	-	26627737	HCT116	viability after 6 days	ATTCTCCAGCAGCTCCGCCACGG	WFS1	ENSG00000109501	2.4164612752504384	[304]	[264,250]	9	hSpCas9	negative selection	1813287
6291981	6292004	4	-	26627737	HCT116	viability after 6 days	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	1.6096387076199747	[746]	[349,362]	8	hSpCas9	negative selection	1813288
6295039	6295062	4	+	26627737	HCT116	viability after 6 days	AGCCAAGAACTACATCGCGCTGG	WFS1	ENSG00000109501	1.0419899381442386	[694]	[534,53]	5	hSpCas9	negative selection	1813289
6277609	6277632	4	-	26627737	HCT116	viability after 8 days	GCCGCTGCGTCTCTAACACCAGG	WFS1	ENSG00000109501	0.20285705991845115	[111]	[79,40,91]	2	hSpCas9	negative selection	1895598
6287120	6287143	4	+	26627737	HCT116	viability after 8 days	CCTTTGAAGAAGTCCTGGAGAGG	WFS1	ENSG00000109501	1.0316279389091045	[150]	[158,172,177]	8	hSpCas9	negative selection	1895600
6289109	6289132	4	-	26627737	HCT116	viability after 8 days	CTCTTCTGTCCGCCAAGCACCGG	WFS1	ENSG00000109501	0.16302167744382368	[575]	[320,267,474]	2	hSpCas9	negative selection	1895601
6291323	6291346	4	-	26627737	HCT116	viability after 8 days	ATTCTCCAGCAGCTCCGCCACGG	WFS1	ENSG00000109501	0.5876469728046142	[169]	[178,102,140]	6	hSpCas9	negative selection	1895602
6291981	6292004	4	-	26627737	HCT116	viability after 8 days	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	0.11141229287441068	[175]	[184,47,82]	1	hSpCas9	negative selection	1895603
6295039	6295062	4	+	26627737	HCT116	viability after 8 days	AGCCAAGAACTACATCGCGCTGG	WFS1	ENSG00000109501	-0.09186044791801784	[422]	[311,144,200]	-1	hSpCas9	negative selection	1895604
6277609	6277632	4	-	26627737	HCT116	viability after 9 days	GCCGCTGCGTCTCTAACACCAGG	WFS1	ENSG00000109501	-1.051214129793373	[412]	[74,35]	-6	hSpCas9	negative selection	1977913
6287120	6287143	4	+	26627737	HCT116	viability after 9 days	CCTTTGAAGAAGTCCTGGAGAGG	WFS1	ENSG00000109501	0.7827219256280673	[611]	[317,251]	5	hSpCas9	negative selection	1977915
6289109	6289132	4	-	26627737	HCT116	viability after 9 days	CTCTTCTGTCCGCCAAGCACCGG	WFS1	ENSG00000109501	-0.09478611548604543	[1159]	[198,361]	0	hSpCas9	negative selection	1977916
6291323	6291346	4	-	26627737	HCT116	viability after 9 days	ATTCTCCAGCAGCTCCGCCACGG	WFS1	ENSG00000109501	1.7649399894703612	[304]	[316,244]	9	hSpCas9	negative selection	1977917
6291981	6292004	4	-	26627737	HCT116	viability after 9 days	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	-0.042676997915210374	[746]	[134,239]	0	hSpCas9	negative selection	1977918
6295039	6295062	4	+	26627737	HCT116	viability after 9 days	AGCCAAGAACTACATCGCGCTGG	WFS1	ENSG00000109501	1.049827586626387	[694]	[367,396]	7	hSpCas9	negative selection	1977919
6277609	6277632	4	-	26627737	HCT116	viability after 12 days	GCCGCTGCGTCTCTAACACCAGG	WFS1	ENSG00000109501	0.6489968552106824	[111]	[118,69,84]	6	hSpCas9	negative selection	2060228
6287120	6287143	4	+	26627737	HCT116	viability after 12 days	CCTTTGAAGAAGTCCTGGAGAGG	WFS1	ENSG00000109501	1.035764646579233	[150]	[76,178,239]	8	hSpCas9	negative selection	2060230
6289109	6289132	4	-	26627737	HCT116	viability after 12 days	CTCTTCTGTCCGCCAAGCACCGG	WFS1	ENSG00000109501	0.5370295458863344	[575]	[350,463,510]	5	hSpCas9	negative selection	2060231
6291323	6291346	4	-	26627737	HCT116	viability after 12 days	ATTCTCCAGCAGCTCCGCCACGG	WFS1	ENSG00000109501	1.0819506885196626	[169]	[206,114,241]	8	hSpCas9	negative selection	2060232
6291981	6292004	4	-	26627737	HCT116	viability after 12 days	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	0.8974955910521294	[175]	[225,164,120]	7	hSpCas9	negative selection	2060233
6295039	6295062	4	+	26627737	HCT116	viability after 12 days	AGCCAAGAACTACATCGCGCTGG	WFS1	ENSG00000109501	-0.340136447380646	[422]	[146,202,179]	-4	hSpCas9	negative selection	2060234
6277609	6277632	4	-	26627737	HCT116	viability after 15 days	GCCGCTGCGTCTCTAACACCAGG	WFS1	ENSG00000109501	0.24702052241419525	[111]	[121,72,39]	2	hSpCas9	negative selection	2142543
6287120	6287143	4	+	26627737	HCT116	viability after 15 days	CCTTTGAAGAAGTCCTGGAGAGG	WFS1	ENSG00000109501	1.0762206461120225	[150]	[163,178,202]	8	hSpCas9	negative selection	2142545
6289109	6289132	4	-	26627737	HCT116	viability after 15 days	CTCTTCTGTCCGCCAAGCACCGG	WFS1	ENSG00000109501	0.3823119352735359	[575]	[448,525,321]	4	hSpCas9	negative selection	2142546
6291323	6291346	4	-	26627737	HCT116	viability after 15 days	ATTCTCCAGCAGCTCCGCCACGG	WFS1	ENSG00000109501	0.5908436339075228	[169]	[159,76,204]	5	hSpCas9	negative selection	2142547
6291981	6292004	4	-	26627737	HCT116	viability after 15 days	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	0.0021644816187028626	[175]	[145,50,111]	0	hSpCas9	negative selection	2142548
6295039	6295062	4	+	26627737	HCT116	viability after 15 days	AGCCAAGAACTACATCGCGCTGG	WFS1	ENSG00000109501	-0.07213523001384065	[422]	[216,282,191]	0	hSpCas9	negative selection	2142549
6277609	6277632	4	-	26627737	HCT116	viability after 18 days	GCCGCTGCGTCTCTAACACCAGG	WFS1	ENSG00000109501	-0.6646066149488816	[111]	[47,23,30]	-6	hSpCas9	negative selection	2224858
6287120	6287143	4	+	26627737	HCT116	viability after 18 days	CCTTTGAAGAAGTCCTGGAGAGG	WFS1	ENSG00000109501	0.6482720794430997	[150]	[35,122,186]	5	hSpCas9	negative selection	2224860
6289109	6289132	4	-	26627737	HCT116	viability after 18 days	CTCTTCTGTCCGCCAAGCACCGG	WFS1	ENSG00000109501	0.6332039457791926	[575]	[214,646,418]	5	hSpCas9	negative selection	2224861
6291323	6291346	4	-	26627737	HCT116	viability after 18 days	ATTCTCCAGCAGCTCCGCCACGG	WFS1	ENSG00000109501	1.2106301105771922	[169]	[184,154,234]	8	hSpCas9	negative selection	2224862
6291981	6292004	4	-	26627737	HCT116	viability after 18 days	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	0.09937348104069177	[175]	[189,45,37]	0	hSpCas9	negative selection	2224863
6295039	6295062	4	+	26627737	HCT116	viability after 18 days	AGCCAAGAACTACATCGCGCTGG	WFS1	ENSG00000109501	0.40659530592668525	[422]	[295,356,148]	3	hSpCas9	negative selection	2224864
6284278	6284301	4	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGAAGAATCGCTTGAACCCGAG	WFS1	ENSG00000109501	0.6947743245442068	[118,16]	[8,38]	3	dCas9-VP64	positive selection	2469053
6284278	6284301	4	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGAAGAATCGCTTGAACCCGAG	WFS1	ENSG00000109501	-1.217410828372933	[137,230]	[25,24]	-9	dCas9-VP64	positive selection	2564308
6300846	6300869	4	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTACCTGTCCTTCATCTCCATGG	WFS1	ENSG00000109501	0.25729824458320216	[4,4]	[4,4]	5	hSpCas9	positive selection	3032523
6291275	6291298	4	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAGCTTCCAGTACATGACCAGGG	WFS1	ENSG00000109501	-0.09896092674260437	[4,4]	[3,3]	-1	hSpCas9	positive selection	3032524
6277547	6277570	4	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTCCTCTCCTGCTCCAACGAGG	WFS1	ENSG00000109501	-0.07999704307966944	[3,3]	[2,3]	-1	hSpCas9	positive selection	3032525
6300877	6300900	4	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGTCCTGGAACACCTTGAGGG	WFS1	ENSG00000109501	-0.13686683604863026	[3,3]	[3,2]	-2	hSpCas9	positive selection	3032526
6300846	6300869	4	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTACCTGTCCTTCATCTCCATGG	WFS1	ENSG00000109501	-0.020642571978829904	[4,4]	[3,2]	0	hSpCas9	positive selection	3100381
6291275	6291298	4	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAGCTTCCAGTACATGACCAGGG	WFS1	ENSG00000109501	-0.5637436289973333	[4,4]	[3,0]	-7	hSpCas9	positive selection	3100382
6277547	6277570	4	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTCCTCTCCTGCTCCAACGAGG	WFS1	ENSG00000109501	-0.3575360886491801	[3,3]	[2,1]	-5	hSpCas9	positive selection	3100383
6300877	6300900	4	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGTCCTGGAACACCTTGAGGG	WFS1	ENSG00000109501	0.08058147108267893	[3,3]	[2,1]	1	hSpCas9	positive selection	3100384
6287082	6287105		+	24336571	A375	resistance to PLX after 7 days	CTGTGTTAAAGGGCCTACAAAGG	WFS1	ENSG00000109501	-0.15589289538973827	[8,6]	[6,6]	-5	hSpCas9	positive selection	3155676
6289012	6289035		-	24336571	A375	resistance to PLX after 7 days	GAGTTCTTCATCCGTGTCGCCGG	WFS1	ENSG00000109501	-0.15620196993400493	[24,21]	[19,21]	-5	hSpCas9	positive selection	3155677
6289058	6289081		+	24336571	A375	resistance to PLX after 7 days	GCTGGTCCTCGCCGCGAAGCAGG	WFS1	ENSG00000109501	-0.14877363451970593	[10,8]	[8,8]	-5	hSpCas9	positive selection	3155678
6287082	6287105		+	24336571	A375	resistance to PLX after 14 days	CTGTGTTAAAGGGCCTACAAAGG	WFS1	ENSG00000109501	0.3399729050069883	[6,5]	[2,3]	3	hSpCas9	positive selection	3213469
6289012	6289035		-	24336571	A375	resistance to PLX after 14 days	GAGTTCTTCATCCGTGTCGCCGG	WFS1	ENSG00000109501	0.7716647981667097	[28,14]	[15,17]	6	hSpCas9	positive selection	3213470
6289058	6289081		+	24336571	A375	resistance to PLX after 14 days	GCTGGTCCTCGCCGCGAAGCAGG	WFS1	ENSG00000109501	0.8608385911399823	[9,6]	[7,5]	7	hSpCas9	positive selection	3213471
6287082	6287105		+	24336571	A375	viability after 7 days	CTGTGTTAAAGGGCCTACAAAGG	WFS1	ENSG00000109501	0.0216706222091243	[7]	[8,6]	0	hSpCas9	negative selection	3271262
6289012	6289035		-	24336571	A375	viability after 7 days	GAGTTCTTCATCCGTGTCGCCGG	WFS1	ENSG00000109501	0.7726046014322732	[13]	[24,21]	9	hSpCas9	negative selection	3271263
6289058	6289081		+	24336571	A375	viability after 7 days	GCTGGTCCTCGCCGCGAAGCAGG	WFS1	ENSG00000109501	0.13383529999009336	[8]	[10,8]	2	hSpCas9	negative selection	3271264
6287082	6287105		+	24336571	A375	viability after 14 days	CTGTGTTAAAGGGCCTACAAAGG	WFS1	ENSG00000109501	-0.22688920110948196	[7]	[6,5]	-3	hSpCas9	negative selection	3329055
6289012	6289035		-	24336571	A375	viability after 14 days	GAGTTCTTCATCCGTGTCGCCGG	WFS1	ENSG00000109501	0.680620221426619	[13]	[28,14]	8	hSpCas9	negative selection	3329056
6289058	6289081		+	24336571	A375	viability after 14 days	GCTGGTCCTCGCCGCGAAGCAGG	WFS1	ENSG00000109501	0.004438744582745402	[8]	[9,6]	0	hSpCas9	negative selection	3329057
6287082	6287105	4	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTGTGTTAAAGGGCCTACAAAGG	WFS1	ENSG00000109501	2.3031299010589596	[30,30]	[0,0]	8	hSpCas9	positive selection	3401459
6289031	6289054	4	+	27383988	293T	resistance to West Nile virus (flavivirus)	ACTCAACAGCTGCACCGCTGTGG	WFS1	ENSG00000109501	1.1280431945008687	[69,69]	[0,0]	5	hSpCas9	positive selection	3401460
6291981	6292004	4	-	27383988	293T	resistance to West Nile virus (flavivirus)	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	-1.5787241436122348	[456,456]	[0,0]	-9	hSpCas9	positive selection	3401461
6300845	6300868	4	+	26780180	HT29	viability (Avana library 4 designs)	CTACCTGTCCTTCATCTCCATGG	WFS1	ENSG00000109501	0.511933465634978	[]	[]	2	hSpCas9	negative selection	3471777
6291275	6291298	4	-	26780180	HT29	viability (Avana library 4 designs)	GAGCTTCCAGTACATGACCAGGG	WFS1	ENSG00000109501	-0.00774682488982656	[]	[]	0	hSpCas9	negative selection	3471778
6277547	6277570	4	-	26780180	HT29	viability (Avana library 4 designs)	GCTCCTCTCCTGCTCCAACGAGG	WFS1	ENSG00000109501	0.662438899084894	[]	[]	2	hSpCas9	negative selection	3471779
6300877	6300900	4	-	26780180	HT29	viability (Avana library 4 designs)	GCTGTCCTGGAACACCTTGAGGG	WFS1	ENSG00000109501	0.727163203743371	[]	[]	2	hSpCas9	negative selection	3471780
6277547	6277570	4	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTCCTCTCCTGCTCCAACGAGG	WFS1	ENSG00000109501	3.84768450907131	[]	[]	6	hSpCas9	negative selection	3578740
6300877	6300900	4	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGTCCTGGAACACCTTGAGGG	WFS1	ENSG00000109501	2.26395034890754	[]	[]	3	hSpCas9	negative selection	3578741
6300845	6300868	4	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTACCTGTCCTTCATCTCCATGG	WFS1	ENSG00000109501	2.03483460795932	[]	[]	3	hSpCas9	negative selection	3578742
6291275	6291298	4	-	26780180	A375	viability (Avana lentiCRISPRv2)	GAGCTTCCAGTACATGACCAGGG	WFS1	ENSG00000109501	4.42214693120235	[]	[]	7	hSpCas9	negative selection	3578743
6289082	6289105	4	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGCTTCACAGCCTCGCGACGG	WFS1	ENSG00000109501	-5.39446083010915	[]	[]	-5	hSpCas9	negative selection	3578744
6291197	6291220	4	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCATCACGTCCGAGAACGAACGG	WFS1	ENSG00000109501	1.22597232257955	[]	[]	1	hSpCas9	negative selection	3578745
6277547	6277570	4	-	26780180	A375	viability (Avana lentiGuide)	GCTCCTCTCCTGCTCCAACGAGG	WFS1	ENSG00000109501	-0.853773008022287	[]	[]	-1	hSpCas9	negative selection	3687399
6300877	6300900	4	-	26780180	A375	viability (Avana lentiGuide)	GCTGTCCTGGAACACCTTGAGGG	WFS1	ENSG00000109501	-4.0608901041958	[]	[]	-7	hSpCas9	negative selection	3687400
6300845	6300868	4	+	26780180	A375	viability (Avana lentiGuide)	CTACCTGTCCTTCATCTCCATGG	WFS1	ENSG00000109501	2.56512807035271	[]	[]	2	hSpCas9	negative selection	3687401
6291275	6291298	4	-	26780180	A375	viability (Avana lentiGuide)	GAGCTTCCAGTACATGACCAGGG	WFS1	ENSG00000109501	2.60759032672467	[]	[]	2	hSpCas9	negative selection	3687402
6289082	6289105	4	-	26780180	A375	viability (Avana lentiGuide)	GCAGCTTCACAGCCTCGCGACGG	WFS1	ENSG00000109501	0.488579565770754	[]	[]	0	hSpCas9	negative selection	3687403
6291197	6291220	4	+	26780180	A375	viability (Avana lentiGuide)	GCATCACGTCCGAGAACGAACGG	WFS1	ENSG00000109501	0.0235026988545984	[]	[]	0	hSpCas9	negative selection	3687404
6277547	6277570	4	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTCCTCTCCTGCTCCAACGAGG	WFS1	ENSG00000109501	0.03056085289522842	[3]	[3,3]	0	hSpCas9	positive selection	3796006
6300877	6300900	4	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGTCCTGGAACACCTTGAGGG	WFS1	ENSG00000109501	-0.000663060396085817	[4]	[6,3]	0	hSpCas9	positive selection	3796007
6300845	6300868	4	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTACCTGTCCTTCATCTCCATGG	WFS1	ENSG00000109501	-0.020205143720623236	[5]	[4,5]	0	hSpCas9	positive selection	3796008
6291275	6291298	4	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGCTTCCAGTACATGACCAGGG	WFS1	ENSG00000109501	0.24746899979166279	[5]	[5,6]	7	hSpCas9	positive selection	3796009
6289082	6289105	4	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGCTTCACAGCCTCGCGACGG	WFS1	ENSG00000109501	-0.17230003338681307	[4]	[3,3]	-3	hSpCas9	positive selection	3796010
6291197	6291220	4	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCATCACGTCCGAGAACGAACGG	WFS1	ENSG00000109501	0.13190044692748323	[4]	[4,4]	3	hSpCas9	positive selection	3796011
6277547	6277570	4	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTCCTCTCCTGCTCCAACGAGG	WFS1	ENSG00000109501	-0.04915051864921133	[5]	[4,4]	0	hSpCas9	positive selection	3904613
6300877	6300900	4	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGTCCTGGAACACCTTGAGGG	WFS1	ENSG00000109501	-0.2311298450834294	[5]	[4,2]	-3	hSpCas9	positive selection	3904614
6300845	6300868	4	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTACCTGTCCTTCATCTCCATGG	WFS1	ENSG00000109501	-0.03473026009727927	[6]	[3,6]	0	hSpCas9	positive selection	3904615
6291275	6291298	4	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGCTTCCAGTACATGACCAGGG	WFS1	ENSG00000109501	0.26772813134916207	[5]	[5,5]	7	hSpCas9	positive selection	3904616
6289082	6289105	4	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGCTTCACAGCCTCGCGACGG	WFS1	ENSG00000109501	-0.27569652451293836	[5]	[2,3]	-4	hSpCas9	positive selection	3904617
6291197	6291220	4	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCATCACGTCCGAGAACGAACGG	WFS1	ENSG00000109501	0.005376237521749122	[4]	[4,3]	0	hSpCas9	positive selection	3904618
6289031	6289054	4	+	26780180	A375	viability	ACTCAACAGCTGCACCGCTGTGG	WFS1	ENSG00000109501	1.31870578484986	[]	[]	7	hSpCas9	negative selection	4012696
6291981	6292004	4	-	26780180	A375	viability	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	0.644379839498941	[]	[]	2	hSpCas9	negative selection	4012697
6287082	6287105	4	+	26780180	A375	viability	CTGTGTTAAAGGGCCTACAAAGG	WFS1	ENSG00000109501	0.897705363560102	[]	[]	4	hSpCas9	negative selection	4012698
6289012	6289035	4	-	26780180	A375	viability	GAGTTCTTCATCCGTGTCGCCGG	WFS1	ENSG00000109501	1.19996592598217	[]	[]	6	hSpCas9	negative selection	4012699
6291197	6291220	4	+	26780180	A375	viability	GCATCACGTCCGAGAACGAACGG	WFS1	ENSG00000109501	0.975436945549562	[]	[]	4	hSpCas9	negative selection	4012700
6291351	6291374	4	-	26780180	A375	viability	TCGCACCGTGCTCGTTGACCTGG	WFS1	ENSG00000109501	1.79004088810627	[]	[]	9	hSpCas9	negative selection	4012701
6289031	6289054	4	+	26780180	HT29	viability (GeCKOv2 library)	ACTCAACAGCTGCACCGCTGTGG	WFS1	ENSG00000109501	1.21053931254828	[]	[]	6	hSpCas9	negative selection	4120662
6291981	6292004	4	-	26780180	HT29	viability (GeCKOv2 library)	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	1.09504811345637	[]	[]	5	hSpCas9	negative selection	4120663
6287082	6287105	4	+	26780180	HT29	viability (GeCKOv2 library)	CTGTGTTAAAGGGCCTACAAAGG	WFS1	ENSG00000109501	0.874850682376569	[]	[]	3	hSpCas9	negative selection	4120664
6289012	6289035	4	-	26780180	HT29	viability (GeCKOv2 library)	GAGTTCTTCATCCGTGTCGCCGG	WFS1	ENSG00000109501	1.6516459844707	[]	[]	8	hSpCas9	negative selection	4120665
6291197	6291220	4	+	26780180	HT29	viability (GeCKOv2 library)	GCATCACGTCCGAGAACGAACGG	WFS1	ENSG00000109501	0.968481161700089	[]	[]	4	hSpCas9	negative selection	4120666
6291351	6291374	4	-	26780180	HT29	viability (GeCKOv2 library)	TCGCACCGTGCTCGTTGACCTGG	WFS1	ENSG00000109501	1.9013749766831	[]	[]	9	hSpCas9	negative selection	4120667
6287082	6287105	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTGTGTTAAAGGGCCTACAAAGG	WFS1	ENSG00000109501	-0.06588303574411941	[2]	[1,1]	-1	hSpCas9	positive selection	4182509
6289012	6289035	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAGTTCTTCATCCGTGTCGCCGG	WFS1	ENSG00000109501	0.1341490034023326	[4]	[2,4]	3	hSpCas9	positive selection	4182510
6289058	6289081	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCTGGTCCTCGCCGCGAAGCAGG	WFS1	ENSG00000109501	0.14482143197561326	[3]	[1,2]	4	hSpCas9	positive selection	4182512
6287082	6287105	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTGTGTTAAAGGGCCTACAAAGG	WFS1	ENSG00000109501	1.7989724412741255	[2]	[3,3,1,4]	9	hSpCas9	positive selection	4246531
6289012	6289035	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAGTTCTTCATCCGTGTCGCCGG	WFS1	ENSG00000109501	0.6069212571029692	[3]	[1,4,4,0]	4	hSpCas9	positive selection	4246532
6289058	6289081	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCTGGTCCTCGCCGCGAAGCAGG	WFS1	ENSG00000109501	-0.16000086001109892	[2]	[1,0,0,0]	-2	hSpCas9	positive selection	4246534
6289012	6289035	4	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAGTTCTTCATCCGTGTCGCCGG	WFS1	ENSG00000109501	-0.31661463308507415	[3]	[3,0]	-6	hSpCas9	positive selection	4307903
6291351	6291374	4	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCGCACCGTGCTCGTTGACCTGG	WFS1	ENSG00000109501	0.06125471109198353	[3]	[2,2]	1	hSpCas9	positive selection	4307904
6291197	6291220	4	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCATCACGTCCGAGAACGAACGG	WFS1	ENSG00000109501	0.10308137583555249	[1]	[2,0]	2	hSpCas9	positive selection	4307905
6287082	6287105	4	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGTGTTAAAGGGCCTACAAAGG	WFS1	ENSG00000109501	-0.6186897927610343	[1]	[0,0]	-8	hSpCas9	positive selection	4372151
6289031	6289054	4	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACTCAACAGCTGCACCGCTGTGG	WFS1	ENSG00000109501	-0.08165631324028383	[2]	[1,1]	-2	hSpCas9	positive selection	4372152
6291981	6292004	4	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	0.13877295198330358	[4]	[4,3]	3	hSpCas9	positive selection	4372153
6277608	6277630	4	-	27760321	OCIAML3	viability	CGCTGCGTCTCTAACACCAGGG	WFS1	ENSG00000109501	-0.5118993357867555	[449,387]	[226,231]	-5	hSpCas9	negative selection	4454199
6289001	6289023	4	-	27760321	OCIAML3	viability	CGTGTCGCCGGCCAACTGCAGG	WFS1	ENSG00000109501	-0.2475890226110221	[862,886]	[492,690]	-3	hSpCas9	negative selection	4454200
6291199	6291221	4	+	27760321	OCIAML3	viability	ATCACGTCCGAGAACGAACGGG	WFS1	ENSG00000109501	-0.5181662266157436	[229,212]	[133,103]	-5	hSpCas9	negative selection	4454201
6291347	6291369	4	+	27760321	OCIAML3	viability	TCGGCCAGGTCAACGAGCACGG	WFS1	ENSG00000109501	0.31606170024000857	[402,364]	[304,462]	3	hSpCas9	negative selection	4454202
6300675	6300697	4	+	27760321	OCIAML3	viability	CACGCCATCATGGAGATCAAGG	WFS1	ENSG00000109501	1.0523643435445489	[583,458]	[769,931]	9	hSpCas9	negative selection	4454203
6277608	6277630	4	-	27760321	OCIAML2	viability	CGCTGCGTCTCTAACACCAGGG	WFS1	ENSG00000109501	0.2528074764061962	[449,387]	[293,545]	3	hSpCas9	negative selection	4537662
6289001	6289023	4	-	27760321	OCIAML2	viability	CGTGTCGCCGGCCAACTGCAGG	WFS1	ENSG00000109501	-0.07442776447116228	[862,886]	[622,743]	-1	hSpCas9	negative selection	4537663
6291199	6291221	4	+	27760321	OCIAML2	viability	ATCACGTCCGAGAACGAACGGG	WFS1	ENSG00000109501	-0.26075923238706444	[229,212]	[127,177]	-3	hSpCas9	negative selection	4537664
6291347	6291369	4	+	27760321	OCIAML2	viability	TCGGCCAGGTCAACGAGCACGG	WFS1	ENSG00000109501	0.018692634488011617	[402,364]	[269,372]	0	hSpCas9	negative selection	4537665
6300675	6300697	4	+	27760321	OCIAML2	viability	CACGCCATCATGGAGATCAAGG	WFS1	ENSG00000109501	0.7397463472618846	[583,458]	[594,837]	8	hSpCas9	negative selection	4537666
6277608	6277630	4	-	27760321	MV411	viability	CGCTGCGTCTCTAACACCAGGG	WFS1	ENSG00000109501	0.7594374656076729	[449,387]	[417,539]	5	hSpCas9	negative selection	4621125
6289001	6289023	4	-	27760321	MV411	viability	CGTGTCGCCGGCCAACTGCAGG	WFS1	ENSG00000109501	0.43322487555102573	[862,886]	[408,1344]	3	hSpCas9	negative selection	4621126
6291199	6291221	4	+	27760321	MV411	viability	ATCACGTCCGAGAACGAACGGG	WFS1	ENSG00000109501	1.2502411843249408	[229,212]	[49,794]	8	hSpCas9	negative selection	4621127
6291347	6291369	4	+	27760321	MV411	viability	TCGGCCAGGTCAACGAGCACGG	WFS1	ENSG00000109501	0.5281480206414569	[402,364]	[293,471]	4	hSpCas9	negative selection	4621128
6300675	6300697	4	+	27760321	MV411	viability	CACGCCATCATGGAGATCAAGG	WFS1	ENSG00000109501	0.6589429626532052	[583,458]	[307,887]	5	hSpCas9	negative selection	4621129
6277608	6277630	4	-	27760321	HL60	viability	CGCTGCGTCTCTAACACCAGGG	WFS1	ENSG00000109501	0.1600248762704955	[449,387]	[475,280]	2	hSpCas9	negative selection	4704588
6289001	6289023	4	-	27760321	HL60	viability	CGTGTCGCCGGCCAACTGCAGG	WFS1	ENSG00000109501	-0.3103530709227761	[862,886]	[527,632]	-4	hSpCas9	negative selection	4704589
6291199	6291221	4	+	27760321	HL60	viability	ATCACGTCCGAGAACGAACGGG	WFS1	ENSG00000109501	0.027225686006653538	[229,212]	[81,292]	0	hSpCas9	negative selection	4704590
6291347	6291369	4	+	27760321	HL60	viability	TCGGCCAGGTCAACGAGCACGG	WFS1	ENSG00000109501	0.677237249007009	[402,364]	[474,528]	7	hSpCas9	negative selection	4704591
6300675	6300697	4	+	27760321	HL60	viability	CACGCCATCATGGAGATCAAGG	WFS1	ENSG00000109501	0.5888116590486595	[583,458]	[553,723]	7	hSpCas9	negative selection	4704592
6277608	6277630	4	-	27760321	HT1080	viability	CGCTGCGTCTCTAACACCAGGG	WFS1	ENSG00000109501	-1.6947366352599986	[387,302]	[63,18]	-6	hSpCas9	negative selection	4788051
6289001	6289023	4	-	27760321	HT1080	viability	CGTGTCGCCGGCCAACTGCAGG	WFS1	ENSG00000109501	-0.24946795747576278	[886,691]	[286,239]	-1	hSpCas9	negative selection	4788052
6291199	6291221	4	+	27760321	HT1080	viability	ATCACGTCCGAGAACGAACGGG	WFS1	ENSG00000109501	2.2974376778304917	[212,165]	[635,80]	9	hSpCas9	negative selection	4788053
6291347	6291369	4	+	27760321	HT1080	viability	TCGGCCAGGTCAACGAGCACGG	WFS1	ENSG00000109501	1.853662261663815	[364,284]	[550,376]	8	hSpCas9	negative selection	4788054
6300675	6300697	4	+	27760321	HT1080	viability	CACGCCATCATGGAGATCAAGG	WFS1	ENSG00000109501	2.1056980020414597	[458,357]	[1087,275]	9	hSpCas9	negative selection	4788055
6277608	6277630	4	-	27760321	HT29	viability after 7 days	CGCTGCGTCTCTAACACCAGGG	WFS1	ENSG00000109501	-0.0988584416553654	[387,302]	[425,422,396]	-1	hSpCas9	negative selection	4871514
6289001	6289023	4	-	27760321	HT29	viability after 7 days	CGTGTCGCCGGCCAACTGCAGG	WFS1	ENSG00000109501	-0.45794381458894606	[886,691]	[768,675,773]	-6	hSpCas9	negative selection	4871515
6291199	6291221	4	+	27760321	HT29	viability after 7 days	ATCACGTCCGAGAACGAACGGG	WFS1	ENSG00000109501	0.2903234381262474	[212,165]	[376,336,193]	4	hSpCas9	negative selection	4871516
6291347	6291369	4	+	27760321	HT29	viability after 7 days	TCGGCCAGGTCAACGAGCACGG	WFS1	ENSG00000109501	0.5583287453858978	[364,284]	[766,428,668]	8	hSpCas9	negative selection	4871517
6300675	6300697	4	+	27760321	HT29	viability after 7 days	CACGCCATCATGGAGATCAAGG	WFS1	ENSG00000109501	0.9177675389433055	[458,357]	[1076,783,1121]	9	hSpCas9	negative selection	4871518
6277608	6277630	4	-	27760321	HT29	viability after 25 days	CGCTGCGTCTCTAACACCAGGG	WFS1	ENSG00000109501	0.5242802814297844	[387,302]	[381,751,581]	6	hSpCas9	negative selection	4954977
6289001	6289023	4	-	27760321	HT29	viability after 25 days	CGTGTCGCCGGCCAACTGCAGG	WFS1	ENSG00000109501	-0.044014576915039516	[886,691]	[613,879,1177]	0	hSpCas9	negative selection	4954978
6291199	6291221	4	+	27760321	HT29	viability after 25 days	ATCACGTCCGAGAACGAACGGG	WFS1	ENSG00000109501	-0.22119682250140338	[212,165]	[107,275,176]	-2	hSpCas9	negative selection	4954979
6291347	6291369	4	+	27760321	HT29	viability after 25 days	TCGGCCAGGTCAACGAGCACGG	WFS1	ENSG00000109501	0.6005649373635344	[364,284]	[596,548,537]	6	hSpCas9	negative selection	4954980
6300675	6300697	4	+	27760321	HT29	viability after 25 days	CACGCCATCATGGAGATCAAGG	WFS1	ENSG00000109501	0.8916942563600692	[458,357]	[685,740,1217]	9	hSpCas9	negative selection	4954981
6277608	6277630	4	-	27760321	HT29	viability after 22 days	CGCTGCGTCTCTAACACCAGGG	WFS1	ENSG00000109501	0.17966879671998204	[387,302]	[632,403,313]	1	hSpCas9	negative selection	5038440
6289001	6289023	4	-	27760321	HT29	viability after 22 days	CGTGTCGCCGGCCAACTGCAGG	WFS1	ENSG00000109501	-0.09695479933043494	[886,691]	[572,996,998]	-1	hSpCas9	negative selection	5038441
6291199	6291221	4	+	27760321	HT29	viability after 22 days	ATCACGTCCGAGAACGAACGGG	WFS1	ENSG00000109501	0.28456534437613346	[212,165]	[277,268,252]	3	hSpCas9	negative selection	5038442
6291347	6291369	4	+	27760321	HT29	viability after 22 days	TCGGCCAGGTCAACGAGCACGG	WFS1	ENSG00000109501	1.0080764072070814	[364,284]	[739,709,817]	9	hSpCas9	negative selection	5038443
6300675	6300697	4	+	27760321	HT29	viability after 22 days	CACGCCATCATGGAGATCAAGG	WFS1	ENSG00000109501	1.0361578157793652	[458,357]	[850,1235,819]	9	hSpCas9	negative selection	5038444
6277608	6277630	4	-	27760321	HT29	viability after 19 days	CGCTGCGTCTCTAACACCAGGG	WFS1	ENSG00000109501	0.46561691845856834	[387,302]	[553,791,300]	4	hSpCas9	negative selection	5121903
6289001	6289023	4	-	27760321	HT29	viability after 19 days	CGTGTCGCCGGCCAACTGCAGG	WFS1	ENSG00000109501	0.4388747370506585	[886,691]	[705,915,1965]	4	hSpCas9	negative selection	5121904
6291199	6291221	4	+	27760321	HT29	viability after 19 days	ATCACGTCCGAGAACGAACGGG	WFS1	ENSG00000109501	0.7936774483930101	[212,165]	[337,280,498]	7	hSpCas9	negative selection	5121905
6291347	6291369	4	+	27760321	HT29	viability after 19 days	TCGGCCAGGTCAACGAGCACGG	WFS1	ENSG00000109501	0.5731120379868753	[364,284]	[776,403,502]	6	hSpCas9	negative selection	5121906
6300675	6300697	4	+	27760321	HT29	viability after 19 days	CACGCCATCATGGAGATCAAGG	WFS1	ENSG00000109501	0.9946064771158194	[458,357]	[1083,1168,568]	9	hSpCas9	negative selection	5121907
6277608	6277630	4	-	27760321	HT29	viability after 16 days	CGCTGCGTCTCTAACACCAGGG	WFS1	ENSG00000109501	-0.04159224821982481	[387,302]	[255,542,311]	0	hSpCas9	negative selection	5205366
6289001	6289023	4	-	27760321	HT29	viability after 16 days	CGTGTCGCCGGCCAACTGCAGG	WFS1	ENSG00000109501	0.06176815154468107	[886,691]	[818,1184,744]	0	hSpCas9	negative selection	5205367
6291199	6291221	4	+	27760321	HT29	viability after 16 days	ATCACGTCCGAGAACGAACGGG	WFS1	ENSG00000109501	0.1917299557137382	[212,165]	[205,200,316]	2	hSpCas9	negative selection	5205368
6291347	6291369	4	+	27760321	HT29	viability after 16 days	TCGGCCAGGTCAACGAGCACGG	WFS1	ENSG00000109501	0.6706739077254651	[364,284]	[416,351,957]	7	hSpCas9	negative selection	5205369
6300675	6300697	4	+	27760321	HT29	viability after 16 days	CACGCCATCATGGAGATCAAGG	WFS1	ENSG00000109501	0.7588511763167859	[458,357]	[706,604,1005]	8	hSpCas9	negative selection	5205370
6277608	6277630	4	-	27760321	HT29	viability after 13 days	CGCTGCGTCTCTAACACCAGGG	WFS1	ENSG00000109501	0.19738803333311133	[387,302]	[511,447,420]	2	hSpCas9	negative selection	5288829
6289001	6289023	4	-	27760321	HT29	viability after 13 days	CGTGTCGCCGGCCAACTGCAGG	WFS1	ENSG00000109501	0.08780148127374288	[886,691]	[765,1225,930]	1	hSpCas9	negative selection	5288830
6291199	6291221	4	+	27760321	HT29	viability after 13 days	ATCACGTCCGAGAACGAACGGG	WFS1	ENSG00000109501	0.18470387883435246	[212,165]	[237,286,225]	2	hSpCas9	negative selection	5288831
6291347	6291369	4	+	27760321	HT29	viability after 13 days	TCGGCCAGGTCAACGAGCACGG	WFS1	ENSG00000109501	0.3261594326875678	[364,284]	[617,298,498]	4	hSpCas9	negative selection	5288832
6300675	6300697	4	+	27760321	HT29	viability after 13 days	CACGCCATCATGGAGATCAAGG	WFS1	ENSG00000109501	1.133512367880771	[458,357]	[1236,835,1044]	9	hSpCas9	negative selection	5288833
6277608	6277630	4	-	27760321	HT29	viability after 10 days	CGCTGCGTCTCTAACACCAGGG	WFS1	ENSG00000109501	-0.23564880487258028	[387,302]	[403,427,270]	-3	hSpCas9	negative selection	5372292
6289001	6289023	4	-	27760321	HT29	viability after 10 days	CGTGTCGCCGGCCAACTGCAGG	WFS1	ENSG00000109501	-0.2134667221033335	[886,691]	[868,735,939]	-3	hSpCas9	negative selection	5372293
6291199	6291221	4	+	27760321	HT29	viability after 10 days	ATCACGTCCGAGAACGAACGGG	WFS1	ENSG00000109501	0.2967458680682856	[212,165]	[249,192,422]	4	hSpCas9	negative selection	5372294
6291347	6291369	4	+	27760321	HT29	viability after 10 days	TCGGCCAGGTCAACGAGCACGG	WFS1	ENSG00000109501	0.6146622296413233	[364,284]	[548,714,602]	8	hSpCas9	negative selection	5372295
6300675	6300697	4	+	27760321	HT29	viability after 10 days	CACGCCATCATGGAGATCAAGG	WFS1	ENSG00000109501	0.42800650428113574	[458,357]	[709,587,755]	6	hSpCas9	negative selection	5372296
6277608	6277630	4	-	27760321	MOLM13	viability	CGCTGCGTCTCTAACACCAGGG	WFS1	ENSG00000109501	1.3845312778990555	[449,387]	[877,391]	8	hSpCas9	negative selection	5455755
6289001	6289023	4	-	27760321	MOLM13	viability	CGTGTCGCCGGCCAACTGCAGG	WFS1	ENSG00000109501	-0.5721827907623239	[862,886]	[245,407]	-4	hSpCas9	negative selection	5455756
6291199	6291221	4	+	27760321	MOLM13	viability	ATCACGTCCGAGAACGAACGGG	WFS1	ENSG00000109501	0.3636757924501902	[229,212]	[95,215]	2	hSpCas9	negative selection	5455757
6291347	6291369	4	+	27760321	MOLM13	viability	TCGGCCAGGTCAACGAGCACGG	WFS1	ENSG00000109501	1.0274953048068043	[402,364]	[322,541]	7	hSpCas9	negative selection	5455758
6300675	6300697	4	+	27760321	MOLM13	viability	CACGCCATCATGGAGATCAAGG	WFS1	ENSG00000109501	1.1272818642744182	[583,458]	[644,632]	7	hSpCas9	negative selection	5455759
6269850	6269873	4	+	27661255	K562	viability	GTGCAGAAGGCCGCGCTAGCCGG	WFS1	ENSG00000109501	0.00494082337360989	[671,750]	[681,472]	0	dCas9-KRAB	negative selection	5522852
6269885	6269908	4	+	27661255	K562	viability	GAGTGCAGATTGCTCCCCCGCGG	WFS1	ENSG00000109501	0.13203363769173615	[1509,1822]	[1489,1422]	4	dCas9-KRAB	negative selection	5522853
6269989	6270012	4	+	27661255	K562	viability	GCCGCGTGCGGCCCACTCACGGG	WFS1	ENSG00000109501	-0.5933577163065846	[305,194]	[164,106]	-8	dCas9-KRAB	negative selection	5522854
6270224	6270247	4	+	27661255	K562	viability	GCCCGAACGGGTCACCCGGGGGG	WFS1	ENSG00000109501	0.01612926907076484	[373,443]	[310,344]	0	dCas9-KRAB	negative selection	5522855
6270291	6270314	4	+	27661255	K562	viability	GGCGGGACAGCAGGCCCGAGAGG	WFS1	ENSG00000109501	0.16432710812077334	[1642,1670]	[1518,1451]	6	dCas9-KRAB	negative selection	5522856
6269843	6269866	4	-	27661255	K562	viability	GCGCGGCCTTCTGCACGAGGGGG	WFS1	ENSG00000109501	0.07731910433702949	[607,591]	[540,475]	2	dCas9-KRAB	negative selection	5522857
6289012	6289035	4	-	27260156	BXPC3	viability	GAGTTCTTCATCCGTGTCGCCGG	WFS1	ENSG00000109501	0.03659562555383711	[902]	[889,1018,1050,905]	0	hSpCas9	negative selection	5580363
6291351	6291374	4	-	27260156	BXPC3	viability	TCGCACCGTGCTCGTTGACCTGG	WFS1	ENSG00000109501	0.008367753029368236	[525]	[399,713,538,563]	0	hSpCas9	negative selection	5580364
6291197	6291220	4	+	27260156	BXPC3	viability	GCATCACGTCCGAGAACGAACGG	WFS1	ENSG00000109501	0.39932716148281366	[179]	[214,257,228,297]	8	hSpCas9	negative selection	5580365
6287082	6287105	4	+	27260156	BXPC3	viability	CTGTGTTAAAGGGCCTACAAAGG	WFS1	ENSG00000109501	-0.10990514054631007	[91]	[96,71,99,86]	-3	hSpCas9	negative selection	5644611
6289031	6289054	4	+	27260156	BXPC3	viability	ACTCAACAGCTGCACCGCTGTGG	WFS1	ENSG00000109501	-0.17575659424505685	[256]	[207,222,243,284]	-4	hSpCas9	negative selection	5644612
6291981	6292004	4	-	27260156	BXPC3	viability	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	0.200236271791584	[1247]	[1340,1554,1530,1583]	4	hSpCas9	negative selection	5644613
6289012	6289035	4	-	27260156	A673	viability	GAGTTCTTCATCCGTGTCGCCGG	WFS1	ENSG00000109501	0.14651155081767664	[902]	[1369,1017,1135,1304]	3	hSpCas9	negative selection	5701614
6291351	6291374	4	-	27260156	A673	viability	TCGCACCGTGCTCGTTGACCTGG	WFS1	ENSG00000109501	-0.003419503377697808	[525]	[787,580,560,607]	0	hSpCas9	negative selection	5701615
6291197	6291220	4	+	27260156	A673	viability	GCATCACGTCCGAGAACGAACGG	WFS1	ENSG00000109501	0.3573453177221029	[179]	[248,358,189,305]	8	hSpCas9	negative selection	5701616
6287082	6287105	4	+	27260156	A673	viability	CTGTGTTAAAGGGCCTACAAAGG	WFS1	ENSG00000109501	-0.04576381883030001	[91]	[105,125,108,84]	-1	hSpCas9	negative selection	5765862
6289031	6289054	4	+	27260156	A673	viability	ACTCAACAGCTGCACCGCTGTGG	WFS1	ENSG00000109501	0.0857768388834772	[256]	[409,278,395,228]	2	hSpCas9	negative selection	5765863
6291981	6292004	4	-	27260156	A673	viability	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	0.033737818818525334	[1247]	[1691,1244,1557,1670]	0	hSpCas9	negative selection	5765864
6289012	6289035	4	-	27260156	A375	viability	GAGTTCTTCATCCGTGTCGCCGG	WFS1	ENSG00000109501	0.304104120257656	[902]	[1681,1135,1355,1040]	4	hSpCas9	negative selection	5822865
6291351	6291374	4	-	27260156	A375	viability	TCGCACCGTGCTCGTTGACCTGG	WFS1	ENSG00000109501	-0.00747787863939503	[525]	[697,819,471,495]	0	hSpCas9	negative selection	5822866
6291197	6291220	4	+	27260156	A375	viability	GCATCACGTCCGAGAACGAACGG	WFS1	ENSG00000109501	0.2171956565635873	[179]	[244,396,195,168]	3	hSpCas9	negative selection	5822867
6287082	6287105	4	+	27260156	A375	viability	CTGTGTTAAAGGGCCTACAAAGG	WFS1	ENSG00000109501	-0.0421005202403304	[91]	[40,167,144,74]	0	hSpCas9	negative selection	5887113
6289031	6289054	4	+	27260156	A375	viability	ACTCAACAGCTGCACCGCTGTGG	WFS1	ENSG00000109501	-0.13129646584618893	[256]	[61,344,343,343]	-2	hSpCas9	negative selection	5887114
6291981	6292004	4	-	27260156	A375	viability	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	0.065138474578742	[1247]	[1525,1486,1636,1447]	0	hSpCas9	negative selection	5887115
6289012	6289035	4	-	27260156	COLO741	viability	GAGTTCTTCATCCGTGTCGCCGG	WFS1	ENSG00000109501	0.0038871632938121126	[902]	[1354,1077,1058]	0	hSpCas9	negative selection	5944116
6291351	6291374	4	-	27260156	COLO741	viability	TCGCACCGTGCTCGTTGACCTGG	WFS1	ENSG00000109501	-0.11194574777817115	[525]	[676,585,606]	-2	hSpCas9	negative selection	5944117
6291197	6291220	4	+	27260156	COLO741	viability	GCATCACGTCCGAGAACGAACGG	WFS1	ENSG00000109501	0.2646946429783956	[179]	[385,183,267]	5	hSpCas9	negative selection	5944118
6287082	6287105	4	+	27260156	COLO741	viability	CTGTGTTAAAGGGCCTACAAAGG	WFS1	ENSG00000109501	-0.31534190350896774	[91]	[126,65,92]	-6	hSpCas9	negative selection	6008364
6289031	6289054	4	+	27260156	COLO741	viability	ACTCAACAGCTGCACCGCTGTGG	WFS1	ENSG00000109501	-0.4703405280648928	[256]	[215,230,259]	-7	hSpCas9	negative selection	6008365
6291981	6292004	4	-	27260156	COLO741	viability	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	0.058025447198309044	[1247]	[1815,1718,1468]	1	hSpCas9	negative selection	6008366
6289012	6289035	4	-	27260156	CAL120	viability	GAGTTCTTCATCCGTGTCGCCGG	WFS1	ENSG00000109501	0.25310827754362286	[902]	[1407,1541,1081]	4	hSpCas9	negative selection	6065367
6291351	6291374	4	-	27260156	CAL120	viability	TCGCACCGTGCTCGTTGACCTGG	WFS1	ENSG00000109501	-0.09278509671170035	[525]	[530,760,537]	-1	hSpCas9	negative selection	6065368
6291197	6291220	4	+	27260156	CAL120	viability	GCATCACGTCCGAGAACGAACGG	WFS1	ENSG00000109501	0.5525035315461778	[179]	[183,302,473]	7	hSpCas9	negative selection	6065369
6287082	6287105	4	+	27260156	CAL120	viability	CTGTGTTAAAGGGCCTACAAAGG	WFS1	ENSG00000109501	0.3192955279289458	[91]	[120,150,152]	5	hSpCas9	negative selection	6129615
6289031	6289054	4	+	27260156	CAL120	viability	ACTCAACAGCTGCACCGCTGTGG	WFS1	ENSG00000109501	-0.24448012574991795	[256]	[534,176,139]	-4	hSpCas9	negative selection	6129616
6291981	6292004	4	-	27260156	CAL120	viability	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	0.0906246826801902	[1247]	[2276,1283,1495]	1	hSpCas9	negative selection	6129617
6289012	6289035	4	-	27260156	CADOES1	viability	GAGTTCTTCATCCGTGTCGCCGG	WFS1	ENSG00000109501	0.26881795553704557	[902]	[890,1205,917,1033]	4	hSpCas9	negative selection	6186618
6291351	6291374	4	-	27260156	CADOES1	viability	TCGCACCGTGCTCGTTGACCTGG	WFS1	ENSG00000109501	-0.1567285785997877	[525]	[411,463,351,530]	-3	hSpCas9	negative selection	6186619
6291197	6291220	4	+	27260156	CADOES1	viability	GCATCACGTCCGAGAACGAACGG	WFS1	ENSG00000109501	0.10434153116903366	[179]	[230,132,191,162]	1	hSpCas9	negative selection	6186620
6287082	6287105	4	+	27260156	CADOES1	viability	CTGTGTTAAAGGGCCTACAAAGG	WFS1	ENSG00000109501	0.11231137746642839	[91]	[89,135,78,63]	2	hSpCas9	negative selection	6250866
6289031	6289054	4	+	27260156	CADOES1	viability	ACTCAACAGCTGCACCGCTGTGG	WFS1	ENSG00000109501	-0.04926520537957846	[256]	[159,263,198,303]	-1	hSpCas9	negative selection	6250867
6291981	6292004	4	-	27260156	CADOES1	viability	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	-0.09399701675496241	[1247]	[1256,981,1031,1077]	-2	hSpCas9	negative selection	6250868
6289012	6289035	4	-	27260156	EWS502	viability	GAGTTCTTCATCCGTGTCGCCGG	WFS1	ENSG00000109501	0.13188646688159245	[902]	[951,969,1063,1229]	2	hSpCas9	negative selection	6307869
6291351	6291374	4	-	27260156	EWS502	viability	TCGCACCGTGCTCGTTGACCTGG	WFS1	ENSG00000109501	0.035724514715102185	[525]	[535,555,572,625]	0	hSpCas9	negative selection	6307870
6291197	6291220	4	+	27260156	EWS502	viability	GCATCACGTCCGAGAACGAACGG	WFS1	ENSG00000109501	0.10005058029169556	[179]	[315,93,214,180]	1	hSpCas9	negative selection	6307871
6287082	6287105	4	+	27260156	EWS502	viability	CTGTGTTAAAGGGCCTACAAAGG	WFS1	ENSG00000109501	-0.37976585033451027	[91]	[13,132,88,67]	-6	hSpCas9	negative selection	6372117
6289031	6289054	4	+	27260156	EWS502	viability	ACTCAACAGCTGCACCGCTGTGG	WFS1	ENSG00000109501	0.33773935541011646	[256]	[453,273,250,386]	6	hSpCas9	negative selection	6372118
6291981	6292004	4	-	27260156	EWS502	viability	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	-0.045922157855899925	[1247]	[1514,1277,989,1302]	-1	hSpCas9	negative selection	6372119
6289012	6289035	4	-	27260156	EW8	viability	GAGTTCTTCATCCGTGTCGCCGG	WFS1	ENSG00000109501	0.17074507280448192	[902]	[948,885,650,849]	3	hSpCas9	negative selection	6429120
6291351	6291374	4	-	27260156	EW8	viability	TCGCACCGTGCTCGTTGACCTGG	WFS1	ENSG00000109501	0.0350416260240933	[525]	[506,438,422,386]	0	hSpCas9	negative selection	6429121
6291197	6291220	4	+	27260156	EW8	viability	GCATCACGTCCGAGAACGAACGG	WFS1	ENSG00000109501	0.5245458499398213	[179]	[188,184,204,257]	8	hSpCas9	negative selection	6429122
6287082	6287105	4	+	27260156	EW8	viability	CTGTGTTAAAGGGCCTACAAAGG	WFS1	ENSG00000109501	-0.1968382234450492	[91]	[24,65,31,137]	-4	hSpCas9	negative selection	6493368
6289031	6289054	4	+	27260156	EW8	viability	ACTCAACAGCTGCACCGCTGTGG	WFS1	ENSG00000109501	-0.059555484963843	[256]	[111,278,238,152]	-1	hSpCas9	negative selection	6493369
6291981	6292004	4	-	27260156	EW8	viability	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	0.07751745380632258	[1247]	[1274,1029,976,1021]	1	hSpCas9	negative selection	6493370
6289012	6289035	4	-	27260156	CORL105	viability	GAGTTCTTCATCCGTGTCGCCGG	WFS1	ENSG00000109501	0.052829874312419034	[902]	[1082,1104,1232,985]	1	hSpCas9	negative selection	6550371
6291351	6291374	4	-	27260156	CORL105	viability	TCGCACCGTGCTCGTTGACCTGG	WFS1	ENSG00000109501	-0.25394149719916664	[525]	[524,444,579,526]	-5	hSpCas9	negative selection	6550372
6291197	6291220	4	+	27260156	CORL105	viability	GCATCACGTCCGAGAACGAACGG	WFS1	ENSG00000109501	0.06589308503162328	[179]	[220,158,331,188]	1	hSpCas9	negative selection	6550373
6287082	6287105	4	+	27260156	CORL105	viability	CTGTGTTAAAGGGCCTACAAAGG	WFS1	ENSG00000109501	-0.11363386573417511	[91]	[77,165,103,48]	-2	hSpCas9	negative selection	6614619
6289031	6289054	4	+	27260156	CORL105	viability	ACTCAACAGCTGCACCGCTGTGG	WFS1	ENSG00000109501	-0.28665708951721924	[256]	[282,207,305,200]	-5	hSpCas9	negative selection	6614620
6291981	6292004	4	-	27260156	CORL105	viability	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	0.005315773699289483	[1247]	[1253,1381,1914,1378]	0	hSpCas9	negative selection	6614621
6289012	6289035	4	-	27260156	HS294T	viability	GAGTTCTTCATCCGTGTCGCCGG	WFS1	ENSG00000109501	0.4980024706659274	[902]	[420,401,488,703]	6	hSpCas9	negative selection	6671622
6291351	6291374	4	-	27260156	HS294T	viability	TCGCACCGTGCTCGTTGACCTGG	WFS1	ENSG00000109501	0.30925451212792204	[525]	[127,205,383,312]	4	hSpCas9	negative selection	6671623
6291197	6291220	4	+	27260156	HS294T	viability	GCATCACGTCCGAGAACGAACGG	WFS1	ENSG00000109501	-0.5800696086841175	[179]	[38,42,52,52]	-7	hSpCas9	negative selection	6671624
6287082	6287105	4	+	27260156	HS294T	viability	CTGTGTTAAAGGGCCTACAAAGG	WFS1	ENSG00000109501	-0.07734201455419498	[91]	[46,23,32,28]	-1	hSpCas9	negative selection	6735870
6289031	6289054	4	+	27260156	HS294T	viability	ACTCAACAGCTGCACCGCTGTGG	WFS1	ENSG00000109501	-0.24635198022591787	[256]	[91,79,83,76]	-3	hSpCas9	negative selection	6735871
6291981	6292004	4	-	27260156	HS294T	viability	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	0.14002256478172215	[1247]	[585,391,477,695]	2	hSpCas9	negative selection	6735872
6289012	6289035	4	-	27260156	HCC44	viability	GAGTTCTTCATCCGTGTCGCCGG	WFS1	ENSG00000109501	0.2289998657639316	[902]	[1771,803,1405,948]	3	hSpCas9	negative selection	6792873
6291351	6291374	4	-	27260156	HCC44	viability	TCGCACCGTGCTCGTTGACCTGG	WFS1	ENSG00000109501	0.05047794994230423	[525]	[548,584,567,742]	0	hSpCas9	negative selection	6792874
6291197	6291220	4	+	27260156	HCC44	viability	GCATCACGTCCGAGAACGAACGG	WFS1	ENSG00000109501	-0.11849422884146543	[179]	[176,105,257,228]	-2	hSpCas9	negative selection	6792875
6287082	6287105	4	+	27260156	HCC44	viability	CTGTGTTAAAGGGCCTACAAAGG	WFS1	ENSG00000109501	0.45272508180388393	[91]	[197,106,247,46]	7	hSpCas9	negative selection	6857121
6289031	6289054	4	+	27260156	HCC44	viability	ACTCAACAGCTGCACCGCTGTGG	WFS1	ENSG00000109501	0.46537621773367854	[256]	[418,449,355,364]	7	hSpCas9	negative selection	6857122
6291981	6292004	4	-	27260156	HCC44	viability	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	0.13365700168875483	[1247]	[1903,1351,1551,1437]	2	hSpCas9	negative selection	6857123
6289012	6289035	4	-	27260156	G402	viability	GAGTTCTTCATCCGTGTCGCCGG	WFS1	ENSG00000109501	0.45987700099315676	[902]	[1268,1605,2063,1106]	6	hSpCas9	negative selection	6914124
6291351	6291374	4	-	27260156	G402	viability	TCGCACCGTGCTCGTTGACCTGG	WFS1	ENSG00000109501	0.11579377192353041	[525]	[778,734,551,725]	1	hSpCas9	negative selection	6914125
6291197	6291220	4	+	27260156	G402	viability	GCATCACGTCCGAGAACGAACGG	WFS1	ENSG00000109501	0.594246874925632	[179]	[468,124,303,429]	7	hSpCas9	negative selection	6914126
6287082	6287105	4	+	27260156	G402	viability	CTGTGTTAAAGGGCCTACAAAGG	WFS1	ENSG00000109501	-0.41842901394206855	[91]	[193,45,102,9]	-5	hSpCas9	negative selection	6978372
6289031	6289054	4	+	27260156	G402	viability	ACTCAACAGCTGCACCGCTGTGG	WFS1	ENSG00000109501	-0.21505254455426626	[256]	[271,343,130,333]	-3	hSpCas9	negative selection	6978373
6291981	6292004	4	-	27260156	G402	viability	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	0.4332955614809866	[1247]	[2937,1528,2006,1849]	5	hSpCas9	negative selection	6978374
6289012	6289035	4	-	27260156	L33	viability	GAGTTCTTCATCCGTGTCGCCGG	WFS1	ENSG00000109501	0.12330709413814511	[902]	[939,370,674,1015]	2	hSpCas9	negative selection	7035375
6291351	6291374	4	-	27260156	L33	viability	TCGCACCGTGCTCGTTGACCTGG	WFS1	ENSG00000109501	-0.21011821475924541	[525]	[432,189,321,410]	-5	hSpCas9	negative selection	7035376
6291197	6291220	4	+	27260156	L33	viability	GCATCACGTCCGAGAACGAACGG	WFS1	ENSG00000109501	0.39024737250910013	[179]	[112,114,180,264]	7	hSpCas9	negative selection	7035377
6287082	6287105	4	+	27260156	L33	viability	CTGTGTTAAAGGGCCTACAAAGG	WFS1	ENSG00000109501	0.09656054767728417	[91]	[57,46,52,136]	2	hSpCas9	negative selection	7099623
6289031	6289054	4	+	27260156	L33	viability	ACTCAACAGCTGCACCGCTGTGG	WFS1	ENSG00000109501	-0.22475287789844367	[256]	[215,94,136,213]	-5	hSpCas9	negative selection	7099624
6291981	6292004	4	-	27260156	L33	viability	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	-0.153496272971114	[1247]	[1063,449,788,1072]	-3	hSpCas9	negative selection	7099625
6289012	6289035	4	-	27260156	K562	viability	GAGTTCTTCATCCGTGTCGCCGG	WFS1	ENSG00000109501	0.5570721559709566	[902]	[1159,1669,1176,775]	7	hSpCas9	negative selection	7156626
6291351	6291374	4	-	27260156	K562	viability	TCGCACCGTGCTCGTTGACCTGG	WFS1	ENSG00000109501	0.33283959980524724	[525]	[419,1195,348,421]	4	hSpCas9	negative selection	7156627
6291197	6291220	4	+	27260156	K562	viability	GCATCACGTCCGAGAACGAACGG	WFS1	ENSG00000109501	0.5681272095317496	[179]	[303,257,88,294]	7	hSpCas9	negative selection	7156628
6287082	6287105	4	+	27260156	K562	viability	CTGTGTTAAAGGGCCTACAAAGG	WFS1	ENSG00000109501	0.11238775489872	[91]	[141,46,106,61]	1	hSpCas9	negative selection	7220874
6289031	6289054	4	+	27260156	K562	viability	ACTCAACAGCTGCACCGCTGTGG	WFS1	ENSG00000109501	-0.17242947366692352	[256]	[219,414,56,136]	-2	hSpCas9	negative selection	7220875
6291981	6292004	4	-	27260156	K562	viability	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	0.28292039117188117	[1247]	[1581,1241,1558,1049]	3	hSpCas9	negative selection	7220876
6289012	6289035	4	-	27260156	HT29	viability	GAGTTCTTCATCCGTGTCGCCGG	WFS1	ENSG00000109501	0.21589593428279574	[902]	[1248,1509,1267,1102]	4	hSpCas9	negative selection	7277877
6291351	6291374	4	-	27260156	HT29	viability	TCGCACCGTGCTCGTTGACCTGG	WFS1	ENSG00000109501	0.22961761897995764	[525]	[851,757,749,653]	4	hSpCas9	negative selection	7277878
6291197	6291220	4	+	27260156	HT29	viability	GCATCACGTCCGAGAACGAACGG	WFS1	ENSG00000109501	0.004443807450768222	[179]	[256,243,148,229]	0	hSpCas9	negative selection	7277879
6287082	6287105	4	+	27260156	HT29	viability	CTGTGTTAAAGGGCCTACAAAGG	WFS1	ENSG00000109501	-0.35222332685004076	[91]	[111,114,101,31]	-6	hSpCas9	negative selection	7342125
6289031	6289054	4	+	27260156	HT29	viability	ACTCAACAGCTGCACCGCTGTGG	WFS1	ENSG00000109501	-0.24601338337569068	[256]	[271,393,208,196]	-5	hSpCas9	negative selection	7342126
6291981	6292004	4	-	27260156	HT29	viability	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	0.15598726249937456	[1247]	[1672,1856,1793,1465]	3	hSpCas9	negative selection	7342127
6289012	6289035	4	-	27260156	MHHES1	viability	GAGTTCTTCATCCGTGTCGCCGG	WFS1	ENSG00000109501	0.1426772500327278	[902]	[1166,1563,962,877]	2	hSpCas9	negative selection	7399128
6291351	6291374	4	-	27260156	MHHES1	viability	TCGCACCGTGCTCGTTGACCTGG	WFS1	ENSG00000109501	0.1120759130187326	[525]	[898,724,638,383]	2	hSpCas9	negative selection	7399129
6291197	6291220	4	+	27260156	MHHES1	viability	GCATCACGTCCGAGAACGAACGG	WFS1	ENSG00000109501	0.1614351778435843	[179]	[344,84,276,200]	3	hSpCas9	negative selection	7399130
6287082	6287105	4	+	27260156	MHHES1	viability	CTGTGTTAAAGGGCCTACAAAGG	WFS1	ENSG00000109501	0.057689387487743105	[91]	[31,88,197,100]	1	hSpCas9	negative selection	7463376
6289031	6289054	4	+	27260156	MHHES1	viability	ACTCAACAGCTGCACCGCTGTGG	WFS1	ENSG00000109501	0.2816418766555845	[256]	[426,337,337,312]	5	hSpCas9	negative selection	7463377
6291981	6292004	4	-	27260156	MHHES1	viability	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	0.040960614164039955	[1247]	[1250,1522,1716,1283]	0	hSpCas9	negative selection	7463378
6289012	6289035	4	-	27260156	MEWO	viability	GAGTTCTTCATCCGTGTCGCCGG	WFS1	ENSG00000109501	0.22749668845189297	[902]	[1037,901,1036]	5	hSpCas9	negative selection	7520379
6291351	6291374	4	-	27260156	MEWO	viability	TCGCACCGTGCTCGTTGACCTGG	WFS1	ENSG00000109501	-0.35162554797482637	[525]	[323,376,443]	-6	hSpCas9	negative selection	7520380
6291197	6291220	4	+	27260156	MEWO	viability	GCATCACGTCCGAGAACGAACGG	WFS1	ENSG00000109501	0.21829247238250193	[179]	[186,187,210]	5	hSpCas9	negative selection	7520381
6287082	6287105	4	+	27260156	MEWO	viability	CTGTGTTAAAGGGCCTACAAAGG	WFS1	ENSG00000109501	-0.23638477619318365	[91]	[112,54,58]	-5	hSpCas9	negative selection	7584627
6289031	6289054	4	+	27260156	MEWO	viability	ACTCAACAGCTGCACCGCTGTGG	WFS1	ENSG00000109501	0.19104890282376386	[256]	[285,196,342]	4	hSpCas9	negative selection	7584628
6291981	6292004	4	-	27260156	MEWO	viability	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	0.035748006688892664	[1247]	[1353,1154,1111]	0	hSpCas9	negative selection	7584629
6289012	6289035	4	-	27260156	LNCAPCLONEFGC	viability	GAGTTCTTCATCCGTGTCGCCGG	WFS1	ENSG00000109501	0.17744588260246763	[902]	[1130,691,1140,778]	2	hSpCas9	negative selection	7641630
6291351	6291374	4	-	27260156	LNCAPCLONEFGC	viability	TCGCACCGTGCTCGTTGACCTGG	WFS1	ENSG00000109501	-0.2901956547527331	[525]	[389,211,435,538]	-4	hSpCas9	negative selection	7641631
6291197	6291220	4	+	27260156	LNCAPCLONEFGC	viability	GCATCACGTCCGAGAACGAACGG	WFS1	ENSG00000109501	0.7085395095104422	[179]	[342,249,183,275]	9	hSpCas9	negative selection	7641632
6287082	6287105	4	+	27260156	LNCAPCLONEFGC	viability	CTGTGTTAAAGGGCCTACAAAGG	WFS1	ENSG00000109501	-0.17746910027616503	[91]	[94,50,74,74]	-3	hSpCas9	negative selection	7705878
6289031	6289054	4	+	27260156	LNCAPCLONEFGC	viability	ACTCAACAGCTGCACCGCTGTGG	WFS1	ENSG00000109501	-0.23709106807179448	[256]	[145,215,205,222]	-4	hSpCas9	negative selection	7705879
6291981	6292004	4	-	27260156	LNCAPCLONEFGC	viability	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	0.129533102191429	[1247]	[1086,1411,1200,1231]	2	hSpCas9	negative selection	7705880
6289012	6289035	4	-	27260156	PANC0327	viability	GAGTTCTTCATCCGTGTCGCCGG	WFS1	ENSG00000109501	0.43752216769638563	[902]	[1030,778,1156,1412]	6	hSpCas9	negative selection	7762881
6291351	6291374	4	-	27260156	PANC0327	viability	TCGCACCGTGCTCGTTGACCTGG	WFS1	ENSG00000109501	-0.3523295581790914	[525]	[434,312,190,536]	-5	hSpCas9	negative selection	7762882
6291197	6291220	4	+	27260156	PANC0327	viability	GCATCACGTCCGAGAACGAACGG	WFS1	ENSG00000109501	-0.3097327593181203	[179]	[285,50,149,51]	-4	hSpCas9	negative selection	7762883
6287082	6287105	4	+	27260156	PANC0327	viability	CTGTGTTAAAGGGCCTACAAAGG	WFS1	ENSG00000109501	0.27909492624454035	[91]	[67,215,69,24]	4	hSpCas9	negative selection	7827129
6289031	6289054	4	+	27260156	PANC0327	viability	ACTCAACAGCTGCACCGCTGTGG	WFS1	ENSG00000109501	0.5508297624089702	[256]	[351,267,494,232]	7	hSpCas9	negative selection	7827130
6291981	6292004	4	-	27260156	PANC0327	viability	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	-0.09163470680793662	[1247]	[1050,977,996,1143]	-1	hSpCas9	negative selection	7827131
6289012	6289035	4	-	27260156	NCIH2009	viability	GAGTTCTTCATCCGTGTCGCCGG	WFS1	ENSG00000109501	0.3994008753053353	[902]	[2181,1315,1599]	5	hSpCas9	negative selection	7884132
6291351	6291374	4	-	27260156	NCIH2009	viability	TCGCACCGTGCTCGTTGACCTGG	WFS1	ENSG00000109501	-0.07757746334518013	[525]	[700,641,746]	-1	hSpCas9	negative selection	7884133
6291197	6291220	4	+	27260156	NCIH2009	viability	GCATCACGTCCGAGAACGAACGG	WFS1	ENSG00000109501	-0.6829096001013157	[179]	[153,110,204]	-7	hSpCas9	negative selection	7884134
6287082	6287105	4	+	27260156	NCIH2009	viability	CTGTGTTAAAGGGCCTACAAAGG	WFS1	ENSG00000109501	-0.18737284382538855	[91]	[138,146,56]	-3	hSpCas9	negative selection	7948380
6289031	6289054	4	+	27260156	NCIH2009	viability	ACTCAACAGCTGCACCGCTGTGG	WFS1	ENSG00000109501	0.023365275364344296	[256]	[484,414,216]	0	hSpCas9	negative selection	7948381
6291981	6292004	4	-	27260156	NCIH2009	viability	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	0.07211488238875696	[1247]	[2350,1796,1450]	1	hSpCas9	negative selection	7948382
6289012	6289035	4	-	27260156	NCIH1373	viability	GAGTTCTTCATCCGTGTCGCCGG	WFS1	ENSG00000109501	0.5015616650183885	[902]	[1999,1149,1384,341]	5	hSpCas9	negative selection	8005383
6291351	6291374	4	-	27260156	NCIH1373	viability	TCGCACCGTGCTCGTTGACCTGG	WFS1	ENSG00000109501	0.0626075527956011	[525]	[651,661,471,178]	0	hSpCas9	negative selection	8005384
6291197	6291220	4	+	27260156	NCIH1373	viability	GCATCACGTCCGAGAACGAACGG	WFS1	ENSG00000109501	-0.09203987459162	[179]	[199,128,320,27]	-1	hSpCas9	negative selection	8005385
6287082	6287105	4	+	27260156	NCIH1373	viability	CTGTGTTAAAGGGCCTACAAAGG	WFS1	ENSG00000109501	0.0830901933983923	[91]	[76,166,109,17]	0	hSpCas9	negative selection	8069631
6289031	6289054	4	+	27260156	NCIH1373	viability	ACTCAACAGCTGCACCGCTGTGG	WFS1	ENSG00000109501	-0.16894999436945357	[256]	[145,317,293,62]	-2	hSpCas9	negative selection	8069632
6291981	6292004	4	-	27260156	NCIH1373	viability	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	0.06391427090358626	[1247]	[1774,1119,1543,390]	0	hSpCas9	negative selection	8069633
6289012	6289035	4	-	27260156	PATU8902	viability	GAGTTCTTCATCCGTGTCGCCGG	WFS1	ENSG00000109501	0.5217011755162646	[902]	[1490,1370,2072,2259]	5	hSpCas9	negative selection	8126634
6291351	6291374	4	-	27260156	PATU8902	viability	TCGCACCGTGCTCGTTGACCTGG	WFS1	ENSG00000109501	-0.050246725436966816	[525]	[783,579,648,840]	0	hSpCas9	negative selection	8126635
6291197	6291220	4	+	27260156	PATU8902	viability	GCATCACGTCCGAGAACGAACGG	WFS1	ENSG00000109501	-0.4127199080229582	[179]	[85,195,120,391]	-4	hSpCas9	negative selection	8126636
6287082	6287105	4	+	27260156	PATU8902	viability	CTGTGTTAAAGGGCCTACAAAGG	WFS1	ENSG00000109501	0.07192306370824442	[91]	[59,322,124,19]	0	hSpCas9	negative selection	8190882
6289031	6289054	4	+	27260156	PATU8902	viability	ACTCAACAGCTGCACCGCTGTGG	WFS1	ENSG00000109501	-0.6890856307110776	[256]	[308,279,66,275]	-6	hSpCas9	negative selection	8190883
6291981	6292004	4	-	27260156	PATU8902	viability	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	0.3868685546200257	[1247]	[1791,3100,2090,2126]	4	hSpCas9	negative selection	8190884
6289012	6289035	4	-	27260156	PANC1	viability	GAGTTCTTCATCCGTGTCGCCGG	WFS1	ENSG00000109501	0.01332454670858374	[902]	[747,799,881,705]	0	hSpCas9	negative selection	8247885
6291351	6291374	4	-	27260156	PANC1	viability	TCGCACCGTGCTCGTTGACCTGG	WFS1	ENSG00000109501	-0.396594026033365	[525]	[302,481,387,240]	-6	hSpCas9	negative selection	8247886
6291197	6291220	4	+	27260156	PANC1	viability	GCATCACGTCCGAGAACGAACGG	WFS1	ENSG00000109501	0.08169297455766533	[179]	[109,229,152,171]	1	hSpCas9	negative selection	8247887
6287082	6287105	4	+	27260156	PANC1	viability	CTGTGTTAAAGGGCCTACAAAGG	WFS1	ENSG00000109501	-0.11837909217524567	[91]	[120,60,56,50]	-2	hSpCas9	negative selection	8312133
6289031	6289054	4	+	27260156	PANC1	viability	ACTCAACAGCTGCACCGCTGTGG	WFS1	ENSG00000109501	-0.08045678699276171	[256]	[178,286,179,202]	-1	hSpCas9	negative selection	8312134
6291981	6292004	4	-	27260156	PANC1	viability	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	-0.09615146291389709	[1247]	[923,984,1100,985]	-1	hSpCas9	negative selection	8312135
6289012	6289035	4	-	27260156	PANC0813	viability	GAGTTCTTCATCCGTGTCGCCGG	WFS1	ENSG00000109501	0.2950219118905619	[902]	[1298,1532,1173,1201]	5	hSpCas9	negative selection	8369136
6291351	6291374	4	-	27260156	PANC0813	viability	TCGCACCGTGCTCGTTGACCTGG	WFS1	ENSG00000109501	-0.03120614760653659	[525]	[710,556,379,768]	0	hSpCas9	negative selection	8369137
6291197	6291220	4	+	27260156	PANC0813	viability	GCATCACGTCCGAGAACGAACGG	WFS1	ENSG00000109501	-0.29991260725028	[179]	[185,248,122,131]	-5	hSpCas9	negative selection	8369138
6287082	6287105	4	+	27260156	PANC0813	viability	CTGTGTTAAAGGGCCTACAAAGG	WFS1	ENSG00000109501	-0.29485398348166836	[91]	[58,146,100,44]	-5	hSpCas9	negative selection	8433384
6289031	6289054	4	+	27260156	PANC0813	viability	ACTCAACAGCTGCACCGCTGTGG	WFS1	ENSG00000109501	0.142664267140726	[256]	[290,290,327,413]	2	hSpCas9	negative selection	8433385
6291981	6292004	4	-	27260156	PANC0813	viability	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	-0.13387281911583004	[1247]	[1559,1225,1355,1226]	-2	hSpCas9	negative selection	8433386
6289012	6289035	4	-	27260156	RDES	viability	GAGTTCTTCATCCGTGTCGCCGG	WFS1	ENSG00000109501	0.3586727624855226	[902]	[1032,1146,1495,1766]	6	hSpCas9	negative selection	8490387
6291351	6291374	4	-	27260156	RDES	viability	TCGCACCGTGCTCGTTGACCTGG	WFS1	ENSG00000109501	-0.024620177742715882	[525]	[502,481,643,794]	0	hSpCas9	negative selection	8490388
6291197	6291220	4	+	27260156	RDES	viability	GCATCACGTCCGAGAACGAACGG	WFS1	ENSG00000109501	0.5173354670490897	[179]	[212,208,412,386]	8	hSpCas9	negative selection	8490389
6287082	6287105	4	+	27260156	RDES	viability	CTGTGTTAAAGGGCCTACAAAGG	WFS1	ENSG00000109501	-0.14701984625456932	[91]	[72,49,113,162]	-2	hSpCas9	negative selection	8554635
6289031	6289054	4	+	27260156	RDES	viability	ACTCAACAGCTGCACCGCTGTGG	WFS1	ENSG00000109501	-0.21509698545688283	[256]	[237,218,308,252]	-4	hSpCas9	negative selection	8554636
6291981	6292004	4	-	27260156	RDES	viability	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	-0.04309451849750001	[1247]	[1125,1270,1421,1851]	0	hSpCas9	negative selection	8554637
6289012	6289035	4	-	27260156	PC3	viability	GAGTTCTTCATCCGTGTCGCCGG	WFS1	ENSG00000109501	0.10947930259477467	[902]	[695,610,1642,1244]	2	hSpCas9	negative selection	8611638
6291351	6291374	4	-	27260156	PC3	viability	TCGCACCGTGCTCGTTGACCTGG	WFS1	ENSG00000109501	-0.1368671905773262	[525]	[246,609,640,527]	-3	hSpCas9	negative selection	8611639
6291197	6291220	4	+	27260156	PC3	viability	GCATCACGTCCGAGAACGAACGG	WFS1	ENSG00000109501	0.2937306358993472	[179]	[110,162,438,288]	6	hSpCas9	negative selection	8611640
6287082	6287105	4	+	27260156	PC3	viability	CTGTGTTAAAGGGCCTACAAAGG	WFS1	ENSG00000109501	-0.284359242733462	[91]	[20,109,111,90]	-6	hSpCas9	negative selection	8675886
6289031	6289054	4	+	27260156	PC3	viability	ACTCAACAGCTGCACCGCTGTGG	WFS1	ENSG00000109501	0.0860188624237328	[256]	[196,213,480,283]	2	hSpCas9	negative selection	8675887
6291981	6292004	4	-	27260156	PC3	viability	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	0.14241681174502485	[1247]	[858,1303,2188,1561]	3	hSpCas9	negative selection	8675888
6289012	6289035	4	-	27260156	PATU8988T	viability	GAGTTCTTCATCCGTGTCGCCGG	WFS1	ENSG00000109501	0.298795200588452	[902]	[1070,1309,866,1069]	5	hSpCas9	negative selection	8732889
6291351	6291374	4	-	27260156	PATU8988T	viability	TCGCACCGTGCTCGTTGACCTGG	WFS1	ENSG00000109501	-0.16745581443321944	[525]	[375,520,421,501]	-3	hSpCas9	negative selection	8732890
6291197	6291220	4	+	27260156	PATU8988T	viability	GCATCACGTCCGAGAACGAACGG	WFS1	ENSG00000109501	0.1321630738682138	[179]	[123,231,110,309]	2	hSpCas9	negative selection	8732891
6287082	6287105	4	+	27260156	PATU8988T	viability	CTGTGTTAAAGGGCCTACAAAGG	WFS1	ENSG00000109501	0.19210299878324788	[91]	[70,71,193,61]	3	hSpCas9	negative selection	8797137
6289031	6289054	4	+	27260156	PATU8988T	viability	ACTCAACAGCTGCACCGCTGTGG	WFS1	ENSG00000109501	-0.2921408519163614	[256]	[169,206,213,221]	-5	hSpCas9	negative selection	8797138
6291981	6292004	4	-	27260156	PATU8988T	viability	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	0.18931565652263815	[1247]	[971,1500,1617,1420]	3	hSpCas9	negative selection	8797139
6289012	6289035	4	-	27260156	T47D	viability	GAGTTCTTCATCCGTGTCGCCGG	WFS1	ENSG00000109501	0.19520772169010692	[902]	[1247,1104,1227,1245]	4	hSpCas9	negative selection	8854140
6291351	6291374	4	-	27260156	T47D	viability	TCGCACCGTGCTCGTTGACCTGG	WFS1	ENSG00000109501	-0.13158570386624052	[525]	[531,631,459,609]	-3	hSpCas9	negative selection	8854141
6291197	6291220	4	+	27260156	T47D	viability	GCATCACGTCCGAGAACGAACGG	WFS1	ENSG00000109501	0.03334348042115165	[179]	[206,166,242,245]	0	hSpCas9	negative selection	8854142
6287082	6287105	4	+	27260156	T47D	viability	CTGTGTTAAAGGGCCTACAAAGG	WFS1	ENSG00000109501	-0.1593138623001078	[91]	[100,86,71,125]	-4	hSpCas9	negative selection	8918388
6289031	6289054	4	+	27260156	T47D	viability	ACTCAACAGCTGCACCGCTGTGG	WFS1	ENSG00000109501	-0.013364778139014821	[256]	[344,248,274,322]	0	hSpCas9	negative selection	8918389
6291981	6292004	4	-	27260156	T47D	viability	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	0.1324009423821333	[1247]	[1627,1292,1654,1830]	3	hSpCas9	negative selection	8918390
6289012	6289035	4	-	27260156	SU8686	viability	GAGTTCTTCATCCGTGTCGCCGG	WFS1	ENSG00000109501	0.32391304354371653	[902]	[907,1020,1366,1241]	5	hSpCas9	negative selection	8975391
6291351	6291374	4	-	27260156	SU8686	viability	TCGCACCGTGCTCGTTGACCTGG	WFS1	ENSG00000109501	-0.44614972987385615	[525]	[315,382,330,527]	-6	hSpCas9	negative selection	8975392
6291197	6291220	4	+	27260156	SU8686	viability	GCATCACGTCCGAGAACGAACGG	WFS1	ENSG00000109501	-0.5067842321020606	[179]	[135,133,130,92]	-7	hSpCas9	negative selection	8975393
6287082	6287105	4	+	27260156	SU8686	viability	CTGTGTTAAAGGGCCTACAAAGG	WFS1	ENSG00000109501	-0.36338703363931124	[91]	[37,82,80,85]	-6	hSpCas9	negative selection	9039639
6289031	6289054	4	+	27260156	SU8686	viability	ACTCAACAGCTGCACCGCTGTGG	WFS1	ENSG00000109501	-0.34649435206838286	[256]	[171,193,202,241]	-5	hSpCas9	negative selection	9039640
6291981	6292004	4	-	27260156	SU8686	viability	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	-0.13156482260017466	[1247]	[1135,977,1051,1404]	-2	hSpCas9	negative selection	9039641
6289012	6289035	4	-	27260156	SKES1	viability	GAGTTCTTCATCCGTGTCGCCGG	WFS1	ENSG00000109501	0.18279143330642045	[902]	[1217,960,1051,883]	4	hSpCas9	negative selection	9096642
6291351	6291374	4	-	27260156	SKES1	viability	TCGCACCGTGCTCGTTGACCTGG	WFS1	ENSG00000109501	-0.011737961134253988	[525]	[788,474,464,394]	0	hSpCas9	negative selection	9096643
6291197	6291220	4	+	27260156	SKES1	viability	GCATCACGTCCGAGAACGAACGG	WFS1	ENSG00000109501	0.26800240504371153	[179]	[257,228,244,145]	5	hSpCas9	negative selection	9096644
6287082	6287105	4	+	27260156	SKES1	viability	CTGTGTTAAAGGGCCTACAAAGG	WFS1	ENSG00000109501	-0.293076561589086	[91]	[77,34,53,121]	-6	hSpCas9	negative selection	9160890
6289031	6289054	4	+	27260156	SKES1	viability	ACTCAACAGCTGCACCGCTGTGG	WFS1	ENSG00000109501	-0.0015999299635229836	[256]	[397,244,178,222]	0	hSpCas9	negative selection	9160891
6291981	6292004	4	-	27260156	SKES1	viability	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	0.09702907968228547	[1247]	[1561,1561,1200,1078]	2	hSpCas9	negative selection	9160892
6289012	6289035	4	-	27260156	TOV112D	viability	GAGTTCTTCATCCGTGTCGCCGG	WFS1	ENSG00000109501	0.06995564848973368	[902]	[893,1055,723,1137]	1	hSpCas9	negative selection	9217893
6291351	6291374	4	-	27260156	TOV112D	viability	TCGCACCGTGCTCGTTGACCTGG	WFS1	ENSG00000109501	-0.02693011718359528	[525]	[502,605,565,415]	0	hSpCas9	negative selection	9217894
6291197	6291220	4	+	27260156	TOV112D	viability	GCATCACGTCCGAGAACGAACGG	WFS1	ENSG00000109501	0.38198564943107693	[179]	[278,310,181,190]	7	hSpCas9	negative selection	9217895
6287082	6287105	4	+	27260156	TOV112D	viability	CTGTGTTAAAGGGCCTACAAAGG	WFS1	ENSG00000109501	0.6223813023697533	[91]	[61,69,96,308]	9	hSpCas9	negative selection	9282141
6289031	6289054	4	+	27260156	TOV112D	viability	ACTCAACAGCTGCACCGCTGTGG	WFS1	ENSG00000109501	0.5432191118184178	[256]	[649,332,316,216]	8	hSpCas9	negative selection	9282142
6291981	6292004	4	-	27260156	TOV112D	viability	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	0.0012559367422024792	[1247]	[1016,1683,887,1492]	0	hSpCas9	negative selection	9282143
6289012	6289035	4	-	27260156	TC71	viability	GAGTTCTTCATCCGTGTCGCCGG	WFS1	ENSG00000109501	0.07022883485032949	[902]	[1044,973,877,1181]	1	hSpCas9	negative selection	9339144
6291351	6291374	4	-	27260156	TC71	viability	TCGCACCGTGCTCGTTGACCTGG	WFS1	ENSG00000109501	0.04645067943209363	[525]	[505,789,465,571]	1	hSpCas9	negative selection	9339145
6291197	6291220	4	+	27260156	TC71	viability	GCATCACGTCCGAGAACGAACGG	WFS1	ENSG00000109501	-0.1670283214693975	[179]	[167,153,180,184]	-4	hSpCas9	negative selection	9339146
6287082	6287105	4	+	27260156	TC71	viability	CTGTGTTAAAGGGCCTACAAAGG	WFS1	ENSG00000109501	0.2697537221280881	[91]	[111,119,119,123]	6	hSpCas9	negative selection	9403392
6289031	6289054	4	+	27260156	TC71	viability	ACTCAACAGCTGCACCGCTGTGG	WFS1	ENSG00000109501	0.09709767061229346	[256]	[247,313,319,296]	2	hSpCas9	negative selection	9403393
6291981	6292004	4	-	27260156	TC71	viability	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	-0.11719666542328055	[1247]	[1154,1317,1232,1228]	-3	hSpCas9	negative selection	9403394
6289012	6289035	4	-	27260156	TC32	viability	GAGTTCTTCATCCGTGTCGCCGG	WFS1	ENSG00000109501	0.509216861121804	[902]	[980,1163,1344,1340]	8	hSpCas9	negative selection	9460395
6291351	6291374	4	-	27260156	TC32	viability	TCGCACCGTGCTCGTTGACCTGG	WFS1	ENSG00000109501	-0.15841108316076166	[525]	[447,290,577,512]	-3	hSpCas9	negative selection	9460396
6291197	6291220	4	+	27260156	TC32	viability	GCATCACGTCCGAGAACGAACGG	WFS1	ENSG00000109501	0.29503173675950745	[179]	[226,166,214,222]	5	hSpCas9	negative selection	9460397
6287082	6287105	4	+	27260156	TC32	viability	CTGTGTTAAAGGGCCTACAAAGG	WFS1	ENSG00000109501	-0.2209168305043261	[91]	[83,25,138,71]	-4	hSpCas9	negative selection	9524643
6289031	6289054	4	+	27260156	TC32	viability	ACTCAACAGCTGCACCGCTGTGG	WFS1	ENSG00000109501	-0.5237102441760374	[256]	[160,87,283,181]	-7	hSpCas9	negative selection	9524644
6291981	6292004	4	-	27260156	TC32	viability	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	0.1387301789523272	[1247]	[1170,933,1625,1582]	2	hSpCas9	negative selection	9524645
6277609	6277632	4	-	27869803	HPAFII	viability after 27 days	GCCGCTGCGTCTCTAACACCAGG	WFS1	ENSG00000109501	-0.39146348553532595	[158]	[30,90,NaN]	-3	hSpCas9	negative selection	9588580
6287120	6287143	4	+	27869803	HPAFII	viability after 27 days	CCTTTGAAGAAGTCCTGGAGAGG	WFS1	ENSG00000109501	-0.38443356222885083	[322]	[80,170,NaN]	-3	hSpCas9	negative selection	9588582
6289109	6289132	4	-	27869803	HPAFII	viability after 27 days	CTCTTCTGTCCGCCAAGCACCGG	WFS1	ENSG00000109501	-0.9763324414329193	[626]	[178,157,NaN]	-6	hSpCas9	negative selection	9588583
6291323	6291346	4	-	27869803	HPAFII	viability after 27 days	ATTCTCCAGCAGCTCCGCCACGG	WFS1	ENSG00000109501	1.1253108214778822	[176]	[274,142,NaN]	8	hSpCas9	negative selection	9588584
6291981	6292004	4	-	27869803	HPAFII	viability after 27 days	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	0.8075067367521447	[180]	[63,251,NaN]	6	hSpCas9	negative selection	9588585
6295039	6295062	4	+	27869803	HPAFII	viability after 27 days	AGCCAAGAACTACATCGCGCTGG	WFS1	ENSG00000109501	0.7030292790214885	[303]	[323,206,NaN]	6	hSpCas9	negative selection	9588586
6277609	6277632	4	-	27869803	HPAFII	viability after 15 days	GCCGCTGCGTCTCTAACACCAGG	WFS1	ENSG00000109501	-0.9814041597029998	[158]	[80,89,NaN]	-7	hSpCas9	negative selection	9671029
6287120	6287143	4	+	27869803	HPAFII	viability after 15 days	CCTTTGAAGAAGTCCTGGAGAGG	WFS1	ENSG00000109501	-0.21140434343160108	[322]	[350,267,NaN]	-2	hSpCas9	negative selection	9671031
6289109	6289132	4	-	27869803	HPAFII	viability after 15 days	CTCTTCTGTCCGCCAAGCACCGG	WFS1	ENSG00000109501	-0.3657798720950053	[626]	[821,336,NaN]	-4	hSpCas9	negative selection	9671032
6291323	6291346	4	-	27869803	HPAFII	viability after 15 days	ATTCTCCAGCAGCTCCGCCACGG	WFS1	ENSG00000109501	0.05670789902494339	[176]	[232,175,NaN]	0	hSpCas9	negative selection	9671033
6291981	6292004	4	-	27869803	HPAFII	viability after 15 days	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	0.7342113929888903	[180]	[412,267,NaN]	7	hSpCas9	negative selection	9671034
6295039	6295062	4	+	27869803	HPAFII	viability after 15 days	AGCCAAGAACTACATCGCGCTGG	WFS1	ENSG00000109501	0.6343171513637336	[303]	[672,403,NaN]	7	hSpCas9	negative selection	9671035
6277609	6277632	4	-	27869803	ASPC1	viability after 36 days	GCCGCTGCGTCTCTAACACCAGG	WFS1	ENSG00000109501	-2.291459594684219	[363]	[0,0,62]	-9	hSpCas9	negative selection	9753478
6287120	6287143	4	+	27869803	ASPC1	viability after 36 days	CCTTTGAAGAAGTCCTGGAGAGG	WFS1	ENSG00000109501	1.093099747596423	[520]	[488,547,185]	8	hSpCas9	negative selection	9753480
6289109	6289132	4	-	27869803	ASPC1	viability after 36 days	CTCTTCTGTCCGCCAAGCACCGG	WFS1	ENSG00000109501	0.5113690743569117	[1343]	[731,585,682]	5	hSpCas9	negative selection	9753481
6291323	6291346	4	-	27869803	ASPC1	viability after 36 days	ATTCTCCAGCAGCTCCGCCACGG	WFS1	ENSG00000109501	1.176620455376759	[476]	[64,898,175]	9	hSpCas9	negative selection	9753482
6291981	6292004	4	-	27869803	ASPC1	viability after 36 days	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	0.1564759423190196	[473]	[208,287,82]	1	hSpCas9	negative selection	9753483
6295039	6295062	4	+	27869803	ASPC1	viability after 36 days	AGCCAAGAACTACATCGCGCTGG	WFS1	ENSG00000109501	-0.21791576870346963	[804]	[421,240,112]	-2	hSpCas9	negative selection	9753484
6277609	6277632	4	-	27869803	PATU8988S	viability after 35 days	GCCGCTGCGTCTCTAACACCAGG	WFS1	ENSG00000109501	0.074943484789471	[374]	[195,121,NaN]	0	hSpCas9	negative selection	9835927
6287120	6287143	4	+	27869803	PATU8988S	viability after 35 days	CCTTTGAAGAAGTCCTGGAGAGG	WFS1	ENSG00000109501	0.3579558567451684	[643]	[293,370,NaN]	4	hSpCas9	negative selection	9835929
6289109	6289132	4	-	27869803	PATU8988S	viability after 35 days	CTCTTCTGTCCGCCAAGCACCGG	WFS1	ENSG00000109501	0.9993763868850929	[956]	[783,756,NaN]	8	hSpCas9	negative selection	9835930
6291323	6291346	4	-	27869803	PATU8988S	viability after 35 days	ATTCTCCAGCAGCTCCGCCACGG	WFS1	ENSG00000109501	-0.11708975348849371	[367]	[205,66,NaN]	-1	hSpCas9	negative selection	9835931
6291981	6292004	4	-	27869803	PATU8988S	viability after 35 days	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	0.6628953767639669	[422]	[369,168,NaN]	7	hSpCas9	negative selection	9835932
6295039	6295062	4	+	27869803	PATU8988S	viability after 35 days	AGCCAAGAACTACATCGCGCTGG	WFS1	ENSG00000109501	-0.8731290881104652	[716]	[226,87,NaN]	-7	hSpCas9	negative selection	9835933
6277609	6277632	4	-	27869803	PATU8988S	viability after 31 days	GCCGCTGCGTCTCTAACACCAGG	WFS1	ENSG00000109501	0.03261638323223259	[374]	[93,227,NaN]	0	hSpCas9	negative selection	9918376
6287120	6287143	4	+	27869803	PATU8988S	viability after 31 days	CCTTTGAAGAAGTCCTGGAGAGG	WFS1	ENSG00000109501	0.3104687522447409	[643]	[361,262,NaN]	4	hSpCas9	negative selection	9918378
6289109	6289132	4	-	27869803	PATU8988S	viability after 31 days	CTCTTCTGTCCGCCAAGCACCGG	WFS1	ENSG00000109501	0.49858552312940385	[956]	[400,714,NaN]	6	hSpCas9	negative selection	9918379
6291323	6291346	4	-	27869803	PATU8988S	viability after 31 days	ATTCTCCAGCAGCTCCGCCACGG	WFS1	ENSG00000109501	-0.4664609695646271	[367]	[103,108,NaN]	-5	hSpCas9	negative selection	9918380
6291981	6292004	4	-	27869803	PATU8988S	viability after 31 days	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	0.02827515150833637	[422]	[204,129,NaN]	0	hSpCas9	negative selection	9918381
6295039	6295062	4	+	27869803	PATU8988S	viability after 31 days	AGCCAAGAACTACATCGCGCTGG	WFS1	ENSG00000109501	-0.6672182575734535	[716]	[161,202,NaN]	-6	hSpCas9	negative selection	9918382
6277609	6277632	4	-	27869803	HPAFII	viability after 35 days	GCCGCTGCGTCTCTAACACCAGG	WFS1	ENSG00000109501	0.10003825609613193	[158]	[42,134,NaN]	0	hSpCas9	negative selection	10000825
6287120	6287143	4	+	27869803	HPAFII	viability after 35 days	CCTTTGAAGAAGTCCTGGAGAGG	WFS1	ENSG00000109501	0.2961887000198526	[322]	[117,293,NaN]	2	hSpCas9	negative selection	10000827
6289109	6289132	4	-	27869803	HPAFII	viability after 35 days	CTCTTCTGTCCGCCAAGCACCGG	WFS1	ENSG00000109501	-0.46809395007188137	[626]	[220,238,NaN]	-3	hSpCas9	negative selection	10000828
6291323	6291346	4	-	27869803	HPAFII	viability after 35 days	ATTCTCCAGCAGCTCCGCCACGG	WFS1	ENSG00000109501	1.6625827284786108	[176]	[460,83,NaN]	9	hSpCas9	negative selection	10000829
6291981	6292004	4	-	27869803	HPAFII	viability after 35 days	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	1.4382083791128042	[180]	[30,492,NaN]	8	hSpCas9	negative selection	10000830
6295039	6295062	4	+	27869803	HPAFII	viability after 35 days	AGCCAAGAACTACATCGCGCTGG	WFS1	ENSG00000109501	0.6693785102344938	[303]	[232,257,NaN]	4	hSpCas9	negative selection	10000831
6277609	6277632	4	-	27869803	HPAFII	viability after 31 days	GCCGCTGCGTCTCTAACACCAGG	WFS1	ENSG00000109501	-0.41573149342365634	[158]	[30,105,NaN]	-3	hSpCas9	negative selection	10083274
6287120	6287143	4	+	27869803	HPAFII	viability after 31 days	CCTTTGAAGAAGTCCTGGAGAGG	WFS1	ENSG00000109501	0.15461000535874164	[322]	[140,267,NaN]	1	hSpCas9	negative selection	10083276
6289109	6289132	4	-	27869803	HPAFII	viability after 31 days	CTCTTCTGTCCGCCAAGCACCGG	WFS1	ENSG00000109501	-0.5947200618346195	[626]	[288,171,NaN]	-4	hSpCas9	negative selection	10083277
6291323	6291346	4	-	27869803	HPAFII	viability after 31 days	ATTCTCCAGCAGCTCCGCCACGG	WFS1	ENSG00000109501	1.4756336064279951	[176]	[415,123,NaN]	9	hSpCas9	negative selection	10083278
6291981	6292004	4	-	27869803	HPAFII	viability after 31 days	ACTCACACTCGCTGCTGACCAGG	WFS1	ENSG00000109501	0.8627885233729387	[180]	[66,312,NaN]	6	hSpCas9	negative selection	10083279
6295039	6295062	4	+	27869803	HPAFII	viability after 31 days	AGCCAAGAACTACATCGCGCTGG	WFS1	ENSG00000109501	0.6519942192422932	[303]	[336,192,NaN]	5	hSpCas9	negative selection	10083280
6289082	6289105	4	-	28162770	P31FUJ	viability	GCAGCTTCACAGCCTCGCGACGG	WFS1	ENSG00000109501	0.37912734390704705	[52]	[80]	4	hSpCas9	negative selection	10265353
6277666	6277689	4	+	28162770	P31FUJ	viability	CGGGAAAGAGCAGACGGCACCGG	WFS1	ENSG00000109501	1.100441203700818	[380]	[959]	9	hSpCas9	negative selection	10265354
6289045	6289068	4	-	28162770	P31FUJ	viability	GAGGACCAGCCAGTCCACAGCGG	WFS1	ENSG00000109501	0.06227467082355265	[140]	[172]	0	hSpCas9	negative selection	10265355
6291201	6291224	4	+	28162770	P31FUJ	viability	CACGTCCGAGAACGAACGGGAGG	WFS1	ENSG00000109501	0.5352510675359248	[100]	[171]	6	hSpCas9	negative selection	10265356
6291306	6291329	4	+	28162770	P31FUJ	viability	GAAGAAGAAGCAGGTGGCCGTGG	WFS1	ENSG00000109501	0.48862253885604934	[167]	[276]	5	hSpCas9	negative selection	10265357
6295075	6295098	4	+	28162770	P31FUJ	viability	GATCACTAAGAAGTACGCCAAGG	WFS1	ENSG00000109501	0.13612337001015307	[150]	[194]	1	hSpCas9	negative selection	10265358
6277632	6277655	4	-	28162770	P31FUJ	viability	GCTGGGCCTGGGGTTCAGCGGGG	WFS1	ENSG00000109501	1.210804447061236	[99]	[271]	9	hSpCas9	negative selection	10265359
6291323	6291346	4	-	28162770	P31FUJ	viability	ATTCTCCAGCAGCTCCGCCACGG	WFS1	ENSG00000109501	0.15385349349464283	[230]	[301]	1	hSpCas9	negative selection	10265360
6291944	6291967	4	+	28162770	P31FUJ	viability	CCAAGTCCCTGCAGAAGCAGAGG	WFS1	ENSG00000109501	0.6480505302926167	[81]	[150]	7	hSpCas9	negative selection	10265361
6295175	6295198	4	-	28162770	P31FUJ	viability	TCACTCACCTTCAGACGCAGTGG	WFS1	ENSG00000109501	-0.21377737873262226	[225]	[228]	-2	hSpCas9	negative selection	10265362
6289082	6289105	4	-	28162770	TF1	viability	GCAGCTTCACAGCCTCGCGACGG	WFS1	ENSG00000109501	NaN	[NaN]	[31]	1	hSpCas9	negative selection	10434719
6277666	6277689	4	+	28162770	TF1	viability	CGGGAAAGAGCAGACGGCACCGG	WFS1	ENSG00000109501	NaN	[NaN]	[511]	1	hSpCas9	negative selection	10434720
6289045	6289068	4	-	28162770	TF1	viability	GAGGACCAGCCAGTCCACAGCGG	WFS1	ENSG00000109501	NaN	[NaN]	[93]	1	hSpCas9	negative selection	10434721
6291201	6291224	4	+	28162770	TF1	viability	CACGTCCGAGAACGAACGGGAGG	WFS1	ENSG00000109501	NaN	[NaN]	[91]	1	hSpCas9	negative selection	10434722
6291306	6291329	4	+	28162770	TF1	viability	GAAGAAGAAGCAGGTGGCCGTGG	WFS1	ENSG00000109501	NaN	[NaN]	[373]	1	hSpCas9	negative selection	10434723
6295075	6295098	4	+	28162770	TF1	viability	GATCACTAAGAAGTACGCCAAGG	WFS1	ENSG00000109501	NaN	[NaN]	[192]	1	hSpCas9	negative selection	10434724
6277632	6277655	4	-	28162770	TF1	viability	GCTGGGCCTGGGGTTCAGCGGGG	WFS1	ENSG00000109501	NaN	[NaN]	[117]	1	hSpCas9	negative selection	10434725
6291323	6291346	4	-	28162770	TF1	viability	ATTCTCCAGCAGCTCCGCCACGG	WFS1	ENSG00000109501	NaN	[NaN]	[167]	1	hSpCas9	negative selection	10434726
6291944	6291967	4	+	28162770	TF1	viability	CCAAGTCCCTGCAGAAGCAGAGG	WFS1	ENSG00000109501	NaN	[NaN]	[146]	1	hSpCas9	negative selection	10434727
6295175	6295198	4	-	28162770	TF1	viability	TCACTCACCTTCAGACGCAGTGG	WFS1	ENSG00000109501	NaN	[NaN]	[79]	1	hSpCas9	negative selection	10434728
6289082	6289105	4	-	28162770	SKM1	viability	GCAGCTTCACAGCCTCGCGACGG	WFS1	ENSG00000109501	0.24212863939771	[10]	[22]	2	hSpCas9	negative selection	10604085
6277666	6277689	4	+	28162770	SKM1	viability	CGGGAAAGAGCAGACGGCACCGG	WFS1	ENSG00000109501	0.14998392580839792	[77]	[152]	1	hSpCas9	negative selection	10604086
6289045	6289068	4	-	28162770	SKM1	viability	GAGGACCAGCCAGTCCACAGCGG	WFS1	ENSG00000109501	-0.23703919730084916	[45]	[68]	-2	hSpCas9	negative selection	10604087
6291201	6291224	4	+	28162770	SKM1	viability	CACGTCCGAGAACGAACGGGAGG	WFS1	ENSG00000109501	-0.022300348507836798	[26]	[46]	0	hSpCas9	negative selection	10604088
6291306	6291329	4	+	28162770	SKM1	viability	GAAGAAGAAGCAGGTGGCCGTGG	WFS1	ENSG00000109501	-0.19546009354944993	[56]	[87]	-2	hSpCas9	negative selection	10604089
6295075	6295098	4	+	28162770	SKM1	viability	GATCACTAAGAAGTACGCCAAGG	WFS1	ENSG00000109501	0.6445661018969203	[54]	[151]	6	hSpCas9	negative selection	10604090
6277632	6277655	4	-	28162770	SKM1	viability	GCTGGGCCTGGGGTTCAGCGGGG	WFS1	ENSG00000109501	0.27485984123058343	[35]	[76]	2	hSpCas9	negative selection	10604091
6291323	6291346	4	-	28162770	SKM1	viability	ATTCTCCAGCAGCTCCGCCACGG	WFS1	ENSG00000109501	0.029134916063511762	[50]	[91]	0	hSpCas9	negative selection	10604092
6291944	6291967	4	+	28162770	SKM1	viability	CCAAGTCCCTGCAGAAGCAGAGG	WFS1	ENSG00000109501	0.4464871379038965	[21]	[52]	4	hSpCas9	negative selection	10604093
6295175	6295198	4	-	28162770	SKM1	viability	TCACTCACCTTCAGACGCAGTGG	WFS1	ENSG00000109501	-0.9374789154419415	[51]	[47]	-6	hSpCas9	negative selection	10604094
6289082	6289105	4	-	28162770	SKM1	viability	GCAGCTTCACAGCCTCGCGACGG	WFS1	ENSG00000109501	0.24212863939771	[10]	[22]	2	hSpCas9	negative selection	10773451
6277666	6277689	4	+	28162770	SKM1	viability	CGGGAAAGAGCAGACGGCACCGG	WFS1	ENSG00000109501	0.14998392580839792	[77]	[152]	1	hSpCas9	negative selection	10773452
6289045	6289068	4	-	28162770	SKM1	viability	GAGGACCAGCCAGTCCACAGCGG	WFS1	ENSG00000109501	-0.23703919730084916	[45]	[68]	-2	hSpCas9	negative selection	10773453
6291201	6291224	4	+	28162770	SKM1	viability	CACGTCCGAGAACGAACGGGAGG	WFS1	ENSG00000109501	-0.022300348507836798	[26]	[46]	0	hSpCas9	negative selection	10773454
6291306	6291329	4	+	28162770	SKM1	viability	GAAGAAGAAGCAGGTGGCCGTGG	WFS1	ENSG00000109501	-0.19546009354944993	[56]	[87]	-2	hSpCas9	negative selection	10773455
6295075	6295098	4	+	28162770	SKM1	viability	GATCACTAAGAAGTACGCCAAGG	WFS1	ENSG00000109501	0.6445661018969203	[54]	[151]	6	hSpCas9	negative selection	10773456
6277632	6277655	4	-	28162770	SKM1	viability	GCTGGGCCTGGGGTTCAGCGGGG	WFS1	ENSG00000109501	0.27485984123058343	[35]	[76]	2	hSpCas9	negative selection	10773457
6291323	6291346	4	-	28162770	SKM1	viability	ATTCTCCAGCAGCTCCGCCACGG	WFS1	ENSG00000109501	0.029134916063511762	[50]	[91]	0	hSpCas9	negative selection	10773458
6291944	6291967	4	+	28162770	SKM1	viability	CCAAGTCCCTGCAGAAGCAGAGG	WFS1	ENSG00000109501	0.4464871379038965	[21]	[52]	4	hSpCas9	negative selection	10773459
6295175	6295198	4	-	28162770	SKM1	viability	TCACTCACCTTCAGACGCAGTGG	WFS1	ENSG00000109501	-0.9374789154419415	[51]	[47]	-6	hSpCas9	negative selection	10773460
6289082	6289105	4	-	28162770	PL21	viability	GCAGCTTCACAGCCTCGCGACGG	WFS1	ENSG00000109501	-0.08936700270566478	[43]	[17]	0	hSpCas9	negative selection	10942817
6277666	6277689	4	+	28162770	PL21	viability	CGGGAAAGAGCAGACGGCACCGG	WFS1	ENSG00000109501	-2.5687411597536483	[258]	[18]	-9	hSpCas9	negative selection	10942818
6289045	6289068	4	-	28162770	PL21	viability	GAGGACCAGCCAGTCCACAGCGG	WFS1	ENSG00000109501	-1.0754948281241072	[183]	[37]	-6	hSpCas9	negative selection	10942819
6291201	6291224	4	+	28162770	PL21	viability	CACGTCCGAGAACGAACGGGAGG	WFS1	ENSG00000109501	2.1017359104283253	[90]	[169]	9	hSpCas9	negative selection	10942820
6291306	6291329	4	+	28162770	PL21	viability	GAAGAAGAAGCAGGTGGCCGTGG	WFS1	ENSG00000109501	0.8595958414346107	[194]	[153]	7	hSpCas9	negative selection	10942821
6295075	6295098	4	+	28162770	PL21	viability	GATCACTAAGAAGTACGCCAAGG	WFS1	ENSG00000109501	0.47173603382653784	[279]	[168]	4	hSpCas9	negative selection	10942822
6277632	6277655	4	-	28162770	PL21	viability	GCTGGGCCTGGGGTTCAGCGGGG	WFS1	ENSG00000109501	1.1221371024880469	[94]	[89]	8	hSpCas9	negative selection	10942823
6291323	6291346	4	-	28162770	PL21	viability	ATTCTCCAGCAGCTCCGCCACGG	WFS1	ENSG00000109501	1.1550517249607823	[129]	[125]	8	hSpCas9	negative selection	10942824
6291944	6291967	4	+	28162770	PL21	viability	CCAAGTCCCTGCAGAAGCAGAGG	WFS1	ENSG00000109501	1.0106618156256075	[64]	[56]	8	hSpCas9	negative selection	10942825
6295175	6295198	4	-	28162770	PL21	viability	TCACTCACCTTCAGACGCAGTGG	WFS1	ENSG00000109501	-0.8477948625743821	[152]	[36]	-5	hSpCas9	negative selection	10942826
6289082	6289105	4	-	28162770	P31FUJ	viability	GCAGCTTCACAGCCTCGCGACGG	WFS1	ENSG00000109501	0.37912734390704705	[52]	[80]	4	hSpCas9	negative selection	11112183
6277666	6277689	4	+	28162770	P31FUJ	viability	CGGGAAAGAGCAGACGGCACCGG	WFS1	ENSG00000109501	1.100441203700818	[380]	[959]	9	hSpCas9	negative selection	11112184
6289045	6289068	4	-	28162770	P31FUJ	viability	GAGGACCAGCCAGTCCACAGCGG	WFS1	ENSG00000109501	0.06227467082355265	[140]	[172]	0	hSpCas9	negative selection	11112185
6291201	6291224	4	+	28162770	P31FUJ	viability	CACGTCCGAGAACGAACGGGAGG	WFS1	ENSG00000109501	0.5352510675359248	[100]	[171]	6	hSpCas9	negative selection	11112186
6291306	6291329	4	+	28162770	P31FUJ	viability	GAAGAAGAAGCAGGTGGCCGTGG	WFS1	ENSG00000109501	0.48862253885604934	[167]	[276]	5	hSpCas9	negative selection	11112187
6295075	6295098	4	+	28162770	P31FUJ	viability	GATCACTAAGAAGTACGCCAAGG	WFS1	ENSG00000109501	0.13612337001015307	[150]	[194]	1	hSpCas9	negative selection	11112188
6277632	6277655	4	-	28162770	P31FUJ	viability	GCTGGGCCTGGGGTTCAGCGGGG	WFS1	ENSG00000109501	1.210804447061236	[99]	[271]	9	hSpCas9	negative selection	11112189
6291323	6291346	4	-	28162770	P31FUJ	viability	ATTCTCCAGCAGCTCCGCCACGG	WFS1	ENSG00000109501	0.15385349349464283	[230]	[301]	1	hSpCas9	negative selection	11112190
6291944	6291967	4	+	28162770	P31FUJ	viability	CCAAGTCCCTGCAGAAGCAGAGG	WFS1	ENSG00000109501	0.6480505302926167	[81]	[150]	7	hSpCas9	negative selection	11112191
6295175	6295198	4	-	28162770	P31FUJ	viability	TCACTCACCTTCAGACGCAGTGG	WFS1	ENSG00000109501	-0.21377737873262226	[225]	[228]	-2	hSpCas9	negative selection	11112192
6289082	6289105	4	-	28162770	OCIAML5	viability	GCAGCTTCACAGCCTCGCGACGG	WFS1	ENSG00000109501	-0.1806893183253675	[26]	[42]	-1	hSpCas9	negative selection	11281549
6277666	6277689	4	+	28162770	OCIAML5	viability	CGGGAAAGAGCAGACGGCACCGG	WFS1	ENSG00000109501	1.0198286033883177	[152]	[559]	8	hSpCas9	negative selection	11281550
6289045	6289068	4	-	28162770	OCIAML5	viability	GAGGACCAGCCAGTCCACAGCGG	WFS1	ENSG00000109501	-0.5676131813952976	[77]	[94]	-4	hSpCas9	negative selection	11281551
6291201	6291224	4	+	28162770	OCIAML5	viability	CACGTCCGAGAACGAACGGGAGG	WFS1	ENSG00000109501	0.14793342913600305	[36]	[73]	1	hSpCas9	negative selection	11281552
6291306	6291329	4	+	28162770	OCIAML5	viability	GAAGAAGAAGCAGGTGGCCGTGG	WFS1	ENSG00000109501	0.048923423304837205	[97]	[182]	0	hSpCas9	negative selection	11281553
6295075	6295098	4	+	28162770	OCIAML5	viability	GATCACTAAGAAGTACGCCAAGG	WFS1	ENSG00000109501	-0.8938867465586242	[174]	[169]	-5	hSpCas9	negative selection	11281554
6277632	6277655	4	-	28162770	OCIAML5	viability	GCTGGGCCTGGGGTTCAGCGGGG	WFS1	ENSG00000109501	0.7708637800561797	[49]	[153]	6	hSpCas9	negative selection	11281555
6291323	6291346	4	-	28162770	OCIAML5	viability	ATTCTCCAGCAGCTCCGCCACGG	WFS1	ENSG00000109501	0.5057810982783082	[118]	[304]	4	hSpCas9	negative selection	11281556
6291944	6291967	4	+	28162770	OCIAML5	viability	CCAAGTCCCTGCAGAAGCAGAGG	WFS1	ENSG00000109501	1.9764529611916493	[28]	[205]	9	hSpCas9	negative selection	11281557
6295175	6295198	4	-	28162770	OCIAML5	viability	TCACTCACCTTCAGACGCAGTGG	WFS1	ENSG00000109501	-0.21927554505222563	[88]	[137]	-2	hSpCas9	negative selection	11281558
6289082	6289105	4	-	28162770	EOL1	viability	GCAGCTTCACAGCCTCGCGACGG	WFS1	ENSG00000109501	-1.783271476936155	[97]	[14]	-8	hSpCas9	negative selection	11450915
6277666	6277689	4	+	28162770	EOL1	viability	CGGGAAAGAGCAGACGGCACCGG	WFS1	ENSG00000109501	-0.3349462765580107	[406]	[169]	-3	hSpCas9	negative selection	11450916
6289045	6289068	4	-	28162770	EOL1	viability	GAGGACCAGCCAGTCCACAGCGG	WFS1	ENSG00000109501	-0.9685370245129536	[311]	[83]	-6	hSpCas9	negative selection	11450917
6291201	6291224	4	+	28162770	EOL1	viability	CACGTCCGAGAACGAACGGGAGG	WFS1	ENSG00000109501	-0.7093243296315681	[179]	[57]	-5	hSpCas9	negative selection	11450918
6291306	6291329	4	+	28162770	EOL1	viability	GAAGAAGAAGCAGGTGGCCGTGG	WFS1	ENSG00000109501	0.052161968154882526	[345]	[188]	0	hSpCas9	negative selection	11450919
6295075	6295098	4	+	28162770	EOL1	viability	GATCACTAAGAAGTACGCCAAGG	WFS1	ENSG00000109501	-0.8156929546285326	[293]	[87]	-5	hSpCas9	negative selection	11450920
6277632	6277655	4	-	28162770	EOL1	viability	GCTGGGCCTGGGGTTCAGCGGGG	WFS1	ENSG00000109501	0.03146297548704635	[77]	[41]	0	hSpCas9	negative selection	11450921
6291323	6291346	4	-	28162770	EOL1	viability	ATTCTCCAGCAGCTCCGCCACGG	WFS1	ENSG00000109501	-0.223350923541779	[194]	[87]	-2	hSpCas9	negative selection	11450922
6291944	6291967	4	+	28162770	EOL1	viability	CCAAGTCCCTGCAGAAGCAGAGG	WFS1	ENSG00000109501	0.01765717596201588	[74]	[39]	0	hSpCas9	negative selection	11450923
6295175	6295198	4	-	28162770	EOL1	viability	TCACTCACCTTCAGACGCAGTGG	WFS1	ENSG00000109501	-0.3728381390540363	[203]	[82]	-3	hSpCas9	negative selection	11450924
6289082	6289105	4	-	28162770	MOLM13	viability	GCAGCTTCACAGCCTCGCGACGG	WFS1	ENSG00000109501	1.4497420348343195	[79]	[157]	9	hSpCas9	negative selection	11620281
6277666	6277689	4	+	28162770	MOLM13	viability	CGGGAAAGAGCAGACGGCACCGG	WFS1	ENSG00000109501	1.1577064943303157	[366]	[591]	8	hSpCas9	negative selection	11620282
6289045	6289068	4	-	28162770	MOLM13	viability	GAGGACCAGCCAGTCCACAGCGG	WFS1	ENSG00000109501	-0.9827720274649863	[204]	[74]	-5	hSpCas9	negative selection	11620283
6291201	6291224	4	+	28162770	MOLM13	viability	CACGTCCGAGAACGAACGGGAGG	WFS1	ENSG00000109501	0.6978949869909019	[161]	[189]	5	hSpCas9	negative selection	11620284
6291306	6291329	4	+	28162770	MOLM13	viability	GAAGAAGAAGCAGGTGGCCGTGG	WFS1	ENSG00000109501	0.046062716603095924	[283]	[211]	0	hSpCas9	negative selection	11620285
6295075	6295098	4	+	28162770	MOLM13	viability	GATCACTAAGAAGTACGCCAAGG	WFS1	ENSG00000109501	0.5621580427609012	[310]	[331]	4	hSpCas9	negative selection	11620286
6277632	6277655	4	-	28162770	MOLM13	viability	GCTGGGCCTGGGGTTCAGCGGGG	WFS1	ENSG00000109501	1.1506992056638794	[75]	[121]	8	hSpCas9	negative selection	11620287
6291323	6291346	4	-	28162770	MOLM13	viability	ATTCTCCAGCAGCTCCGCCACGG	WFS1	ENSG00000109501	0.6324611484926845	[239]	[268]	5	hSpCas9	negative selection	11620288
6291944	6291967	4	+	28162770	MOLM13	viability	CCAAGTCCCTGCAGAAGCAGAGG	WFS1	ENSG00000109501	-0.7423283258457669	[117]	[50]	-4	hSpCas9	negative selection	11620289
6295175	6295198	4	-	28162770	MOLM13	viability	TCACTCACCTTCAGACGCAGTGG	WFS1	ENSG00000109501	-0.044316776741263164	[347]	[243]	0	hSpCas9	negative selection	11620290
6289082	6289105	4	-	28162770	HEL	viability	GCAGCTTCACAGCCTCGCGACGG	WFS1	ENSG00000109501	-0.7722986672784868	[47]	[17]	-5	hSpCas9	negative selection	11789647
6277666	6277689	4	+	28162770	HEL	viability	CGGGAAAGAGCAGACGGCACCGG	WFS1	ENSG00000109501	-0.04354837868267397	[316]	[196]	0	hSpCas9	negative selection	11789648
6289045	6289068	4	-	28162770	HEL	viability	GAGGACCAGCCAGTCCACAGCGG	WFS1	ENSG00000109501	-0.05971723173923976	[178]	[109]	0	hSpCas9	negative selection	11789649
6291201	6291224	4	+	28162770	HEL	viability	CACGTCCGAGAACGAACGGGAGG	WFS1	ENSG00000109501	0.8850996695694011	[163]	[193]	7	hSpCas9	negative selection	11789650
6291306	6291329	4	+	28162770	HEL	viability	GAAGAAGAAGCAGGTGGCCGTGG	WFS1	ENSG00000109501	0.9815407454521153	[237]	[300]	8	hSpCas9	negative selection	11789651
6295075	6295098	4	+	28162770	HEL	viability	GATCACTAAGAAGTACGCCAAGG	WFS1	ENSG00000109501	0.45009375405796115	[295]	[258]	4	hSpCas9	negative selection	11789652
6277632	6277655	4	-	28162770	HEL	viability	GCTGGGCCTGGGGTTCAGCGGGG	WFS1	ENSG00000109501	0.20833600785458195	[99]	[73]	1	hSpCas9	negative selection	11789653
6291323	6291346	4	-	28162770	HEL	viability	ATTCTCCAGCAGCTCCGCCACGG	WFS1	ENSG00000109501	0.9981268428330446	[178]	[228]	8	hSpCas9	negative selection	11789654
6291944	6291967	4	+	28162770	HEL	viability	CCAAGTCCCTGCAGAAGCAGAGG	WFS1	ENSG00000109501	0.4702716359955912	[70]	[62]	4	hSpCas9	negative selection	11789655
6295175	6295198	4	-	28162770	HEL	viability	TCACTCACCTTCAGACGCAGTGG	WFS1	ENSG00000109501	0.057776331279200746	[227]	[151]	0	hSpCas9	negative selection	11789656
6289082	6289105	4	-	28162770	MV411	viability	GCAGCTTCACAGCCTCGCGACGG	WFS1	ENSG00000109501	-0.07449054410458711	[29]	[23]	0	hSpCas9	negative selection	11959013
6277666	6277689	4	+	28162770	MV411	viability	CGGGAAAGAGCAGACGGCACCGG	WFS1	ENSG00000109501	0.8608564975531596	[250]	[383]	7	hSpCas9	negative selection	11959014
6289045	6289068	4	-	28162770	MV411	viability	GAGGACCAGCCAGTCCACAGCGG	WFS1	ENSG00000109501	-0.40791427782977896	[125]	[79]	-3	hSpCas9	negative selection	11959015
6291201	6291224	4	+	28162770	MV411	viability	CACGTCCGAGAACGAACGGGAGG	WFS1	ENSG00000109501	0.6727433855154463	[104]	[140]	6	hSpCas9	negative selection	11959016
6291306	6291329	4	+	28162770	MV411	viability	GAAGAAGAAGCAGGTGGCCGTGG	WFS1	ENSG00000109501	0.5431761216892749	[188]	[231]	5	hSpCas9	negative selection	11959017
6295075	6295098	4	+	28162770	MV411	viability	GATCACTAAGAAGTACGCCAAGG	WFS1	ENSG00000109501	0.5349250003411081	[194]	[237]	5	hSpCas9	negative selection	11959018
6277632	6277655	4	-	28162770	MV411	viability	GCTGGGCCTGGGGTTCAGCGGGG	WFS1	ENSG00000109501	1.6892751094053342	[59]	[162]	9	hSpCas9	negative selection	11959019
6291323	6291346	4	-	28162770	MV411	viability	ATTCTCCAGCAGCTCCGCCACGG	WFS1	ENSG00000109501	-0.7067587596040998	[154]	[79]	-5	hSpCas9	negative selection	11959020
6291944	6291967	4	+	28162770	MV411	viability	CCAAGTCCCTGCAGAAGCAGAGG	WFS1	ENSG00000109501	0.9393152554204437	[51]	[83]	8	hSpCas9	negative selection	11959021
6295175	6295198	4	-	28162770	MV411	viability	TCACTCACCTTCAGACGCAGTGG	WFS1	ENSG00000109501	0.27491828720488243	[155]	[158]	2	hSpCas9	negative selection	11959022
6289082	6289105	4	-	28162770	MONOMAC1	viability	GCAGCTTCACAGCCTCGCGACGG	WFS1	ENSG00000109501	0.6696966220769822	[33]	[61]	6	hSpCas9	negative selection	12128379
6277666	6277689	4	+	28162770	MONOMAC1	viability	CGGGAAAGAGCAGACGGCACCGG	WFS1	ENSG00000109501	0.9035271195077299	[186]	[400]	8	hSpCas9	negative selection	12128380
6289045	6289068	4	-	28162770	MONOMAC1	viability	GAGGACCAGCCAGTCCACAGCGG	WFS1	ENSG00000109501	1.1143605803356391	[109]	[272]	8	hSpCas9	negative selection	12128381
6291201	6291224	4	+	28162770	MONOMAC1	viability	CACGTCCGAGAACGAACGGGAGG	WFS1	ENSG00000109501	-0.21841049785212052	[67]	[66]	-2	hSpCas9	negative selection	12128382
6291306	6291329	4	+	28162770	MONOMAC1	viability	GAAGAAGAAGCAGGTGGCCGTGG	WFS1	ENSG00000109501	0.7473491777294466	[118]	[228]	7	hSpCas9	negative selection	12128383
6295075	6295098	4	+	28162770	MONOMAC1	viability	GATCACTAAGAAGTACGCCAAGG	WFS1	ENSG00000109501	0.14400007077551333	[119]	[151]	1	hSpCas9	negative selection	12128384
6277632	6277655	4	-	28162770	MONOMAC1	viability	GCTGGGCCTGGGGTTCAGCGGGG	WFS1	ENSG00000109501	0.27244843624166637	[51]	[71]	2	hSpCas9	negative selection	12128385
6291323	6291346	4	-	28162770	MONOMAC1	viability	ATTCTCCAGCAGCTCCGCCACGG	WFS1	ENSG00000109501	1.0508906663840318	[87]	[208]	8	hSpCas9	negative selection	12128386
6291944	6291967	4	+	28162770	MONOMAC1	viability	CCAAGTCCCTGCAGAAGCAGAGG	WFS1	ENSG00000109501	-0.6331359618662271	[45]	[33]	-5	hSpCas9	negative selection	12128387
6295175	6295198	4	-	28162770	MONOMAC1	viability	TCACTCACCTTCAGACGCAGTGG	WFS1	ENSG00000109501	0.14488272301527466	[85]	[108]	1	hSpCas9	negative selection	12128388
6289082	6289105	4	-	28162770	OCIAML2	viability	GCAGCTTCACAGCCTCGCGACGG	WFS1	ENSG00000109501	-0.011198206604863925	[11]	[65]	0	hSpCas9	negative selection	12297745
6277666	6277689	4	+	28162770	OCIAML2	viability	CGGGAAAGAGCAGACGGCACCGG	WFS1	ENSG00000109501	1.121600675943034	[32]	[397]	9	hSpCas9	negative selection	12297746
6289045	6289068	4	-	28162770	OCIAML2	viability	GAGGACCAGCCAGTCCACAGCGG	WFS1	ENSG00000109501	-0.028792266619602075	[29]	[162]	0	hSpCas9	negative selection	12297747
6291201	6291224	4	+	28162770	OCIAML2	viability	CACGTCCGAGAACGAACGGGAGG	WFS1	ENSG00000109501	0.4742286205653778	[19]	[153]	4	hSpCas9	negative selection	12297748
6291306	6291329	4	+	28162770	OCIAML2	viability	GAAGAAGAAGCAGGTGGCCGTGG	WFS1	ENSG00000109501	0.4333432869840629	[32]	[246]	4	hSpCas9	negative selection	12297749
6295075	6295098	4	+	28162770	OCIAML2	viability	GATCACTAAGAAGTACGCCAAGG	WFS1	ENSG00000109501	-0.3153515997642503	[43]	[195]	-3	hSpCas9	negative selection	12297750
6277632	6277655	4	-	28162770	OCIAML2	viability	GCTGGGCCTGGGGTTCAGCGGGG	WFS1	ENSG00000109501	0.44265854156450823	[14]	[112]	4	hSpCas9	negative selection	12297751
6291323	6291346	4	-	28162770	OCIAML2	viability	ATTCTCCAGCAGCTCCGCCACGG	WFS1	ENSG00000109501	-0.2393042791357054	[22]	[107]	-2	hSpCas9	negative selection	12297752
6291944	6291967	4	+	28162770	OCIAML2	viability	CCAAGTCCCTGCAGAAGCAGAGG	WFS1	ENSG00000109501	0.42983450120692435	[14]	[111]	4	hSpCas9	negative selection	12297753
6295175	6295198	4	-	28162770	OCIAML2	viability	TCACTCACCTTCAGACGCAGTGG	WFS1	ENSG00000109501	0.07369069098164904	[23]	[139]	0	hSpCas9	negative selection	12297754
6289082	6289105	4	-	28162770	OCIAML3	viability	GCAGCTTCACAGCCTCGCGACGG	WFS1	ENSG00000109501	-0.13457602168686567	[11]	[32]	-1	hSpCas9	negative selection	12467111
6277666	6277689	4	+	28162770	OCIAML3	viability	CGGGAAAGAGCAGACGGCACCGG	WFS1	ENSG00000109501	0.8006236482928435	[88]	[467]	7	hSpCas9	negative selection	12467112
6289045	6289068	4	-	28162770	OCIAML3	viability	GAGGACCAGCCAGTCCACAGCGG	WFS1	ENSG00000109501	0.40599235967583674	[50]	[203]	4	hSpCas9	negative selection	12467113
6291201	6291224	4	+	28162770	OCIAML3	viability	CACGTCCGAGAACGAACGGGAGG	WFS1	ENSG00000109501	-1.0360121872032764	[35]	[52]	-6	hSpCas9	negative selection	12467114
6291306	6291329	4	+	28162770	OCIAML3	viability	GAAGAAGAAGCAGGTGGCCGTGG	WFS1	ENSG00000109501	0.39177850045613594	[50]	[201]	3	hSpCas9	negative selection	12467115
6295075	6295098	4	+	28162770	OCIAML3	viability	GATCACTAAGAAGTACGCCAAGG	WFS1	ENSG00000109501	-1.3449800924842485	[68]	[81]	-7	hSpCas9	negative selection	12467116
6277632	6277655	4	-	28162770	OCIAML3	viability	GCTGGGCCTGGGGTTCAGCGGGG	WFS1	ENSG00000109501	0.23786960086750986	[24]	[88]	2	hSpCas9	negative selection	12467117
6291323	6291346	4	-	28162770	OCIAML3	viability	ATTCTCCAGCAGCTCCGCCACGG	WFS1	ENSG00000109501	-0.47426839605006754	[51]	[112]	-4	hSpCas9	negative selection	12467118
6291944	6291967	4	+	28162770	OCIAML3	viability	CCAAGTCCCTGCAGAAGCAGAGG	WFS1	ENSG00000109501	0.42034765265290674	[24]	[100]	4	hSpCas9	negative selection	12467119
6295175	6295198	4	-	28162770	OCIAML3	viability	TCACTCACCTTCAGACGCAGTGG	WFS1	ENSG00000109501	0.020101206056509474	[48]	[149]	0	hSpCas9	negative selection	12467120