Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 7498
• Symbol: XDH
• Description: xanthine dehydrogenase

DataSource: http://genomecrispr.dkfz.de/#!/results/XDH

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
31401235	31401258	2	-	26472758	Jiyoye	viability	GAATAGGAAGCACCAAGACGAGG	XDH	ENSG00000158125	0.9886233980507927	[136]	[204]	6	hSpCas9	negative selection	182605
31379866	31379889	2	-	26472758	Jiyoye	viability	AGAGATCCCCTACAGCAGGGAGG	XDH	ENSG00000158125	-0.06607673171826606	[117]	[84]	0	hSpCas9	negative selection	182606
31383000	31383023	2	-	26472758	Jiyoye	viability	GAAGCAAGTCAAGTCTGTGGCGG	XDH	ENSG00000158125	0.9224071688373181	[218]	[312]	6	hSpCas9	negative selection	182607
31337783	31337806	2	+	26472758	Jiyoye	viability	GAAGCAGCCAGGAAGAGGGGCGG	XDH	ENSG00000158125	-1.0826298861749426	[131]	[46]	-6	hSpCas9	negative selection	182608
31398677	31398700	2	-	26472758	Jiyoye	viability	GAGAGAATTGCCAAAAGCCACGG	XDH	ENSG00000158125	0.28431863372034005	[48]	[44]	2	hSpCas9	negative selection	182609
31397667	31397690	2	-	26472758	Jiyoye	viability	GGGCTTCCGGACCTTTGCCAGGG	XDH	ENSG00000158125	0.42174818259314606	[196]	[198]	3	hSpCas9	negative selection	182610
31386513	31386536	2	-	26472758	Jiyoye	viability	GAAGCAGCTGCGATTTGAAGGGG	XDH	ENSG00000158125	-3.9591468327399424	[164]	[7]	-9	hSpCas9	negative selection	182611
31383063	31383086	2	-	26472758	Jiyoye	viability	GCTTCCTGCCCAAAAGACAGAGG	XDH	ENSG00000158125	0.11139957447447968	[204]	[166]	0	hSpCas9	negative selection	182612
31381679	31381702	2	+	26472758	Jiyoye	viability	GTTGAGGTCGGAGATGGGGCTGG	XDH	ENSG00000158125	-4.7013490752722955	[68]	[1]	-9	hSpCas9	negative selection	182613
31379917	31379940	2	+	26472758	Jiyoye	viability	GCAGGGTCTTTCTGTAGCCAGGG	XDH	ENSG00000158125	0.1485394395695967	[261]	[218]	1	hSpCas9	negative selection	182614
31401235	31401258	2	-	26472758	KBM7	viability	GAATAGGAAGCACCAAGACGAGG	XDH	ENSG00000158125	0.32057487546878305	[781,653]	[583,272]	3	hSpCas9	negative selection	373723
31379866	31379889	2	-	26472758	KBM7	viability	AGAGATCCCCTACAGCAGGGAGG	XDH	ENSG00000158125	0.4971136396957637	[257,256]	[139,199]	5	hSpCas9	negative selection	373724
31383000	31383023	2	-	26472758	KBM7	viability	GAAGCAAGTCAAGTCTGTGGCGG	XDH	ENSG00000158125	0.2320676558219863	[709,907]	[453,454]	2	hSpCas9	negative selection	373725
31337783	31337806	2	+	26472758	KBM7	viability	GAAGCAGCCAGGAAGAGGGGCGG	XDH	ENSG00000158125	-1.2270525357163486	[717,339]	[104,100]	-7	hSpCas9	negative selection	373726
31398677	31398700	2	-	26472758	KBM7	viability	GAGAGAATTGCCAAAAGCCACGG	XDH	ENSG00000158125	0.3052322888834182	[439,223]	[226,151]	3	hSpCas9	negative selection	373727
31397667	31397690	2	-	26472758	KBM7	viability	GGGCTTCCGGACCTTTGCCAGGG	XDH	ENSG00000158125	0.6084683131933	[626,377]	[468,248]	6	hSpCas9	negative selection	373728
31386513	31386536	2	-	26472758	KBM7	viability	GAAGCAGCTGCGATTTGAAGGGG	XDH	ENSG00000158125	0.056918865450317435	[101,180]	[89,54]	0	hSpCas9	negative selection	373729
31383063	31383086	2	-	26472758	KBM7	viability	GCTTCCTGCCCAAAAGACAGAGG	XDH	ENSG00000158125	0.8793572924595016	[416,546]	[477,376]	8	hSpCas9	negative selection	373730
31381679	31381702	2	+	26472758	KBM7	viability	GTTGAGGTCGGAGATGGGGCTGG	XDH	ENSG00000158125	-2.3499016610061654	[296,184]	[15,26]	-9	hSpCas9	negative selection	373731
31379917	31379940	2	+	26472758	KBM7	viability	GCAGGGTCTTTCTGTAGCCAGGG	XDH	ENSG00000158125	0.5962762358139642	[959,629]	[548,561]	6	hSpCas9	negative selection	373732
31401235	31401258	2	-	26472758	Raji	viability	GAATAGGAAGCACCAAGACGAGG	XDH	ENSG00000158125	-0.14895621788618604	[300]	[62]	-1	hSpCas9	negative selection	564841
31379866	31379889	2	-	26472758	Raji	viability	AGAGATCCCCTACAGCAGGGAGG	XDH	ENSG00000158125	-0.2383913014681306	[182]	[35]	-2	hSpCas9	negative selection	564842
31383000	31383023	2	-	26472758	Raji	viability	GAAGCAAGTCAAGTCTGTGGCGG	XDH	ENSG00000158125	0.23744407593797234	[423]	[115]	2	hSpCas9	negative selection	564843
31337783	31337806	2	+	26472758	Raji	viability	GAAGCAGCCAGGAAGAGGGGCGG	XDH	ENSG00000158125	-2.98007930587674	[203]	[5]	-9	hSpCas9	negative selection	564844
31398677	31398700	2	-	26472758	Raji	viability	GAGAGAATTGCCAAAAGCCACGG	XDH	ENSG00000158125	1.0281568442230244	[130]	[61]	8	hSpCas9	negative selection	564845
31397667	31397690	2	-	26472758	Raji	viability	GGGCTTCCGGACCTTTGCCAGGG	XDH	ENSG00000158125	0.3867030247948827	[322]	[97]	3	hSpCas9	negative selection	564846
31386513	31386536	2	-	26472758	Raji	viability	GAAGCAGCTGCGATTTGAAGGGG	XDH	ENSG00000158125	0.24488705912353426	[119]	[32]	2	hSpCas9	negative selection	564847
31383063	31383086	2	-	26472758	Raji	viability	GCTTCCTGCCCAAAAGACAGAGG	XDH	ENSG00000158125	0.9425295234787091	[212]	[94]	8	hSpCas9	negative selection	564848
31381679	31381702	2	+	26472758	Raji	viability	GTTGAGGTCGGAGATGGGGCTGG	XDH	ENSG00000158125	-0.7127954270415884	[112]	[15]	-5	hSpCas9	negative selection	564849
31379917	31379940	2	+	26472758	Raji	viability	GCAGGGTCTTTCTGTAGCCAGGG	XDH	ENSG00000158125	0.16373438975496302	[476]	[123]	1	hSpCas9	negative selection	564850
31401235	31401258	2	-	26472758	K562	viability	GAATAGGAAGCACCAAGACGAGG	XDH	ENSG00000158125	0.7116075089963975	[488]	[675]	6	hSpCas9	negative selection	755959
31379866	31379889	2	-	26472758	K562	viability	AGAGATCCCCTACAGCAGGGAGG	XDH	ENSG00000158125	-1.1240519531579456	[314]	[121]	-6	hSpCas9	negative selection	755960
31383000	31383023	2	-	26472758	K562	viability	GAAGCAAGTCAAGTCTGTGGCGG	XDH	ENSG00000158125	0.2895066171949847	[944]	[974]	2	hSpCas9	negative selection	755961
31337783	31337806	2	+	26472758	K562	viability	GAAGCAGCCAGGAAGAGGGGCGG	XDH	ENSG00000158125	-3.7902274151404445	[589]	[35]	-9	hSpCas9	negative selection	755962
31398677	31398700	2	-	26472758	K562	viability	GAGAGAATTGCCAAAAGCCACGG	XDH	ENSG00000158125	0.6902184807159778	[231]	[315]	5	hSpCas9	negative selection	755963
31397667	31397690	2	-	26472758	K562	viability	GGGCTTCCGGACCTTTGCCAGGG	XDH	ENSG00000158125	0.3468807613300205	[393]	[422]	2	hSpCas9	negative selection	755964
31386513	31386536	2	-	26472758	K562	viability	GAAGCAGCTGCGATTTGAAGGGG	XDH	ENSG00000158125	-0.8517965875928564	[185]	[86]	-5	hSpCas9	negative selection	755965
31383063	31383086	2	-	26472758	K562	viability	GCTTCCTGCCCAAAAGACAGAGG	XDH	ENSG00000158125	-0.15704036511185632	[563]	[426]	-1	hSpCas9	negative selection	755966
31381679	31381702	2	+	26472758	K562	viability	GTTGAGGTCGGAGATGGGGCTGG	XDH	ENSG00000158125	-2.180602860185019	[289]	[53]	-7	hSpCas9	negative selection	755967
31379917	31379940	2	+	26472758	K562	viability	GCAGGGTCTTTCTGTAGCCAGGG	XDH	ENSG00000158125	0.2960514960817694	[740]	[767]	2	hSpCas9	negative selection	755968
31377102	31377125	2	-	26627737	DLD1	viability	GGCCCTTTGCTATGGTGGAATGG	XDH	ENSG00000158125	-0.03827639668806221	[355]	[119,121,86]	0	hSpCas9	negative selection	811730
31383084	31383107	2	+	26627737	DLD1	viability	GCTTAGCAACAGCATCCACCAGG	XDH	ENSG00000158125	0.46901891386332034	[636]	[306,414,132]	5	hSpCas9	negative selection	811731
31383754	31383777	2	-	26627737	DLD1	viability	TCGGTAGAACATGGACCCGACGG	XDH	ENSG00000158125	0.8890623226398275	[320]	[136,278,150]	8	hSpCas9	negative selection	811732
31397708	31397731	2	-	26627737	DLD1	viability	GGAAATCTGTGCCGCTGCACAGG	XDH	ENSG00000158125	0.17863106435729503	[300]	[103,157,65]	1	hSpCas9	negative selection	811733
31398634	31398657	2	+	26627737	DLD1	viability	CATACTCATGACGATGCCAGGGG	XDH	ENSG00000158125	-0.6169731855537601	[433]	[53,112,97]	-6	hSpCas9	negative selection	811734
31403109	31403132	2	-	26627737	DLD1	viability	AACCAAGCTCGGCTGTGGAGAGG	XDH	ENSG00000158125	-0.11194663971992483	[402]	[121,84,137]	-1	hSpCas9	negative selection	811735
31377102	31377125	2	-	26627737	GBM cells	viability after 5 days	GGCCCTTTGCTATGGTGGAATGG	XDH	ENSG00000158125	0.5509905714653786	[237]	[193,179]	7	hSpCas9	negative selection	894045
31383084	31383107	2	+	26627737	GBM cells	viability after 5 days	GCTTAGCAACAGCATCCACCAGG	XDH	ENSG00000158125	-0.029295442046304132	[195]	[102,102]	0	hSpCas9	negative selection	894046
31383754	31383777	2	-	26627737	GBM cells	viability after 5 days	TCGGTAGAACATGGACCCGACGG	XDH	ENSG00000158125	0.23641477369350894	[128]	[76,85]	3	hSpCas9	negative selection	894047
31397708	31397731	2	-	26627737	GBM cells	viability after 5 days	GGAAATCTGTGCCGCTGCACAGG	XDH	ENSG00000158125	0.049054224313546	[154]	[58,112]	0	hSpCas9	negative selection	894048
31398634	31398657	2	+	26627737	GBM cells	viability after 5 days	CATACTCATGACGATGCCAGGGG	XDH	ENSG00000158125	0.0660238607209439	[284]	[166,152]	1	hSpCas9	negative selection	894049
31403109	31403132	2	-	26627737	GBM cells	viability after 5 days	AACCAAGCTCGGCTGTGGAGAGG	XDH	ENSG00000158125	0.33998923506605266	[150]	[101,102]	5	hSpCas9	negative selection	894050
31377102	31377125	2	-	26627737	GBM cells	viability after 13 days	GGCCCTTTGCTATGGTGGAATGG	XDH	ENSG00000158125	1.1091235650543059	[237]	[293,265]	9	hSpCas9	negative selection	976360
31383084	31383107	2	+	26627737	GBM cells	viability after 13 days	GCTTAGCAACAGCATCCACCAGG	XDH	ENSG00000158125	-0.47549623919089984	[195]	[81,71]	-5	hSpCas9	negative selection	976361
31383754	31383777	2	-	26627737	GBM cells	viability after 13 days	TCGGTAGAACATGGACCCGACGG	XDH	ENSG00000158125	0.49604749466499126	[128]	[74,117]	6	hSpCas9	negative selection	976362
31397708	31397731	2	-	26627737	GBM cells	viability after 13 days	GGAAATCTGTGCCGCTGCACAGG	XDH	ENSG00000158125	-0.25326668065269486	[154]	[85,57]	-3	hSpCas9	negative selection	976363
31398634	31398657	2	+	26627737	GBM cells	viability after 13 days	CATACTCATGACGATGCCAGGGG	XDH	ENSG00000158125	0.012959209078131306	[284]	[144,164]	0	hSpCas9	negative selection	976364
31403109	31403132	2	-	26627737	GBM cells	viability after 13 days	AACCAAGCTCGGCTGTGGAGAGG	XDH	ENSG00000158125	-0.28121577479704707	[150]	[78,57]	-3	hSpCas9	negative selection	976365
31377102	31377125	2	-	26627737	GBM cells	viability after 21 days	GGCCCTTTGCTATGGTGGAATGG	XDH	ENSG00000158125	1.3781145739652743	[237]	[380,294]	9	hSpCas9	negative selection	1058675
31383084	31383107	2	+	26627737	GBM cells	viability after 21 days	GCTTAGCAACAGCATCCACCAGG	XDH	ENSG00000158125	0.10332656869039208	[195]	[116,111]	1	hSpCas9	negative selection	1058676
31383754	31383777	2	-	26627737	GBM cells	viability after 21 days	TCGGTAGAACATGGACCCGACGG	XDH	ENSG00000158125	0.798691854711007	[128]	[123,119]	7	hSpCas9	negative selection	1058677
31397708	31397731	2	-	26627737	GBM cells	viability after 21 days	GGAAATCTGTGCCGCTGCACAGG	XDH	ENSG00000158125	-0.7383146119315113	[154]	[50,49]	-6	hSpCas9	negative selection	1058678
31398634	31398657	2	+	26627737	GBM cells	viability after 21 days	CATACTCATGACGATGCCAGGGG	XDH	ENSG00000158125	0.029500272681431378	[284]	[168,147]	0	hSpCas9	negative selection	1058679
31403109	31403132	2	-	26627737	GBM cells	viability after 21 days	AACCAAGCTCGGCTGTGGAGAGG	XDH	ENSG00000158125	-0.18980574750347712	[150]	[61,80]	-2	hSpCas9	negative selection	1058680
31377102	31377125	2	-	26627737	RPE1	viability after 9 days	GGCCCTTTGCTATGGTGGAATGG	XDH	ENSG00000158125	1.447467794134662	[327]	[245,323]	7	hSpCas9	negative selection	1140990
31383084	31383107	2	+	26627737	RPE1	viability after 9 days	GCTTAGCAACAGCATCCACCAGG	XDH	ENSG00000158125	0.9062289737573839	[552]	[337,306]	6	hSpCas9	negative selection	1140991
31383754	31383777	2	-	26627737	RPE1	viability after 9 days	TCGGTAGAACATGGACCCGACGG	XDH	ENSG00000158125	0.18295390378140686	[432]	[190,105]	1	hSpCas9	negative selection	1140992
31397708	31397731	2	-	26627737	RPE1	viability after 9 days	GGAAATCTGTGCCGCTGCACAGG	XDH	ENSG00000158125	1.0748397832797965	[253]	[108,242]	6	hSpCas9	negative selection	1140993
31398634	31398657	2	+	26627737	RPE1	viability after 9 days	CATACTCATGACGATGCCAGGGG	XDH	ENSG00000158125	0.4314353884771642	[624]	[200,344]	3	hSpCas9	negative selection	1140994
31403109	31403132	2	-	26627737	RPE1	viability after 9 days	AACCAAGCTCGGCTGTGGAGAGG	XDH	ENSG00000158125	0.4794481657285907	[311]	[133,138]	3	hSpCas9	negative selection	1140995
31377102	31377125	2	-	26627737	RPE1	viability after 12 days	GGCCCTTTGCTATGGTGGAATGG	XDH	ENSG00000158125	1.8342299613711297	[327]	[304,323]	8	hSpCas9	negative selection	1223305
31383084	31383107	2	+	26627737	RPE1	viability after 12 days	GCTTAGCAACAGCATCCACCAGG	XDH	ENSG00000158125	1.041959411263643	[552]	[268,344]	6	hSpCas9	negative selection	1223306
31383754	31383777	2	-	26627737	RPE1	viability after 12 days	TCGGTAGAACATGGACCCGACGG	XDH	ENSG00000158125	-1.1459047690541784	[432]	[54,49]	-7	hSpCas9	negative selection	1223307
31397708	31397731	2	-	26627737	RPE1	viability after 12 days	GGAAATCTGTGCCGCTGCACAGG	XDH	ENSG00000158125	0.7500464540014722	[253]	[123,104]	5	hSpCas9	negative selection	1223308
31398634	31398657	2	+	26627737	RPE1	viability after 12 days	CATACTCATGACGATGCCAGGGG	XDH	ENSG00000158125	0.18172161728897018	[624]	[171,209]	1	hSpCas9	negative selection	1223309
31403109	31403132	2	-	26627737	RPE1	viability after 12 days	AACCAAGCTCGGCTGTGGAGAGG	XDH	ENSG00000158125	1.0600347366036758	[311]	[234,110]	6	hSpCas9	negative selection	1223310
31377102	31377125	2	-	26627737	RPE1	viability after 15 days	GGCCCTTTGCTATGGTGGAATGG	XDH	ENSG00000158125	1.4752216908828029	[327]	[259,255]	7	hSpCas9	negative selection	1305620
31383084	31383107	2	+	26627737	RPE1	viability after 15 days	GCTTAGCAACAGCATCCACCAGG	XDH	ENSG00000158125	0.9466706985813121	[552]	[300,301]	5	hSpCas9	negative selection	1305621
31383754	31383777	2	-	26627737	RPE1	viability after 15 days	TCGGTAGAACATGGACCCGACGG	XDH	ENSG00000158125	-0.09075724579921207	[432]	[113,115]	0	hSpCas9	negative selection	1305622
31397708	31397731	2	-	26627737	RPE1	viability after 15 days	GGAAATCTGTGCCGCTGCACAGG	XDH	ENSG00000158125	0.8147154076233281	[253]	[132,119]	5	hSpCas9	negative selection	1305623
31398634	31398657	2	+	26627737	RPE1	viability after 15 days	CATACTCATGACGATGCCAGGGG	XDH	ENSG00000158125	0.436200131462473	[624]	[198,277]	3	hSpCas9	negative selection	1305624
31403109	31403132	2	-	26627737	RPE1	viability after 15 days	AACCAAGCTCGGCTGTGGAGAGG	XDH	ENSG00000158125	-0.27423125516640057	[311]	[45,98]	-2	hSpCas9	negative selection	1305625
31377102	31377125	2	-	26627737	RPE1	viability after 18 days	GGCCCTTTGCTATGGTGGAATGG	XDH	ENSG00000158125	1.4203978327304607	[327]	[190,285]	7	hSpCas9	negative selection	1387935
31383084	31383107	2	+	26627737	RPE1	viability after 18 days	GCTTAGCAACAGCATCCACCAGG	XDH	ENSG00000158125	1.2000989159177735	[552]	[251,439]	6	hSpCas9	negative selection	1387936
31383754	31383777	2	-	26627737	RPE1	viability after 18 days	TCGGTAGAACATGGACCCGACGG	XDH	ENSG00000158125	-1.8926866170988808	[432]	[15,47]	-8	hSpCas9	negative selection	1387937
31397708	31397731	2	-	26627737	RPE1	viability after 18 days	GGAAATCTGTGCCGCTGCACAGG	XDH	ENSG00000158125	0.48102329114997633	[253]	[56,136]	3	hSpCas9	negative selection	1387938
31398634	31398657	2	+	26627737	RPE1	viability after 18 days	CATACTCATGACGATGCCAGGGG	XDH	ENSG00000158125	0.5190946063384164	[624]	[276,203]	3	hSpCas9	negative selection	1387939
31403109	31403132	2	-	26627737	RPE1	viability after 18 days	AACCAAGCTCGGCTGTGGAGAGG	XDH	ENSG00000158125	0.3105451769813141	[311]	[72,137]	2	hSpCas9	negative selection	1387940
31377102	31377125	2	-	26627737	HeLa	viability after 8 days	GGCCCTTTGCTATGGTGGAATGG	XDH	ENSG00000158125	0.47408585106889345	[379]	[248,239,205]	4	hSpCas9	negative selection	1470250
31383084	31383107	2	+	26627737	HeLa	viability after 8 days	GCTTAGCAACAGCATCCACCAGG	XDH	ENSG00000158125	2.400840544560644	[65]	[196,249,26]	9	hSpCas9	negative selection	1470251
31383754	31383777	2	-	26627737	HeLa	viability after 8 days	TCGGTAGAACATGGACCCGACGG	XDH	ENSG00000158125	0.15969088716923652	[362]	[203,163,167]	1	hSpCas9	negative selection	1470252
31397708	31397731	2	-	26627737	HeLa	viability after 8 days	GGAAATCTGTGCCGCTGCACAGG	XDH	ENSG00000158125	1.294058682671335	[110]	[114,97,139]	8	hSpCas9	negative selection	1470253
31398634	31398657	2	+	26627737	HeLa	viability after 8 days	CATACTCATGACGATGCCAGGGG	XDH	ENSG00000158125	-0.6707594930750742	[521]	[92,75,240]	-6	hSpCas9	negative selection	1470254
31403109	31403132	2	-	26627737	HeLa	viability after 8 days	AACCAAGCTCGGCTGTGGAGAGG	XDH	ENSG00000158125	0.41612405130762387	[266]	[140,17,292]	4	hSpCas9	negative selection	1470255
31377102	31377125	2	-	26627737	HeLa	viability after 12 days	GGCCCTTTGCTATGGTGGAATGG	XDH	ENSG00000158125	0.526295563999273	[379]	[217,209,251]	4	hSpCas9	negative selection	1552565
31383084	31383107	2	+	26627737	HeLa	viability after 12 days	GCTTAGCAACAGCATCCACCAGG	XDH	ENSG00000158125	2.73589500120573	[65]	[64,178,297]	9	hSpCas9	negative selection	1552566
31383754	31383777	2	-	26627737	HeLa	viability after 12 days	TCGGTAGAACATGGACCCGACGG	XDH	ENSG00000158125	-0.1882229595226939	[362]	[41,191,151]	-2	hSpCas9	negative selection	1552567
31397708	31397731	2	-	26627737	HeLa	viability after 12 days	GGAAATCTGTGCCGCTGCACAGG	XDH	ENSG00000158125	1.277713904001805	[110]	[166,94,74]	8	hSpCas9	negative selection	1552568
31398634	31398657	2	+	26627737	HeLa	viability after 12 days	CATACTCATGACGATGCCAGGGG	XDH	ENSG00000158125	-0.4297088078054787	[521]	[134,185,155]	-4	hSpCas9	negative selection	1552569
31403109	31403132	2	-	26627737	HeLa	viability after 12 days	AACCAAGCTCGGCTGTGGAGAGG	XDH	ENSG00000158125	0.3318901986370095	[266]	[54,121,238]	3	hSpCas9	negative selection	1552570
31377102	31377125	2	-	26627737	HeLa	viability after 15 days	GGCCCTTTGCTATGGTGGAATGG	XDH	ENSG00000158125	0.2570285590920679	[379]	[143,94,326]	2	hSpCas9	negative selection	1634880
31383084	31383107	2	+	26627737	HeLa	viability after 15 days	GCTTAGCAACAGCATCCACCAGG	XDH	ENSG00000158125	2.4424334438955175	[65]	[154,88,197]	9	hSpCas9	negative selection	1634881
31383754	31383777	2	-	26627737	HeLa	viability after 15 days	TCGGTAGAACATGGACCCGACGG	XDH	ENSG00000158125	-0.05680381632557331	[362]	[226,129,61]	0	hSpCas9	negative selection	1634882
31397708	31397731	2	-	26627737	HeLa	viability after 15 days	GGAAATCTGTGCCGCTGCACAGG	XDH	ENSG00000158125	1.4647043905772679	[110]	[175,90,104]	8	hSpCas9	negative selection	1634883
31398634	31398657	2	+	26627737	HeLa	viability after 15 days	CATACTCATGACGATGCCAGGGG	XDH	ENSG00000158125	-0.6811595625051803	[521]	[143,65,191]	-5	hSpCas9	negative selection	1634884
31403109	31403132	2	-	26627737	HeLa	viability after 15 days	AACCAAGCTCGGCTGTGGAGAGG	XDH	ENSG00000158125	-0.04704874945533788	[266]	[23,98,200]	0	hSpCas9	negative selection	1634885
31377102	31377125	2	-	26627737	HeLa	viability after 18 days	GGCCCTTTGCTATGGTGGAATGG	XDH	ENSG00000158125	0.2288751893144266	[379]	[90,76,326]	2	hSpCas9	negative selection	1717195
31383084	31383107	2	+	26627737	HeLa	viability after 18 days	GCTTAGCAACAGCATCCACCAGG	XDH	ENSG00000158125	2.5042868789946993	[65]	[116,72,197]	9	hSpCas9	negative selection	1717196
31383754	31383777	2	-	26627737	HeLa	viability after 18 days	TCGGTAGAACATGGACCCGACGG	XDH	ENSG00000158125	0.03509176143179264	[362]	[166,111,61]	0	hSpCas9	negative selection	1717197
31397708	31397731	2	-	26627737	HeLa	viability after 18 days	GGAAATCTGTGCCGCTGCACAGG	XDH	ENSG00000158125	1.458921119284556	[110]	[118,72,104]	8	hSpCas9	negative selection	1717198
31398634	31398657	2	+	26627737	HeLa	viability after 18 days	CATACTCATGACGATGCCAGGGG	XDH	ENSG00000158125	-0.6619204438509076	[521]	[98,55,191]	-5	hSpCas9	negative selection	1717199
31403109	31403132	2	-	26627737	HeLa	viability after 18 days	AACCAAGCTCGGCTGTGGAGAGG	XDH	ENSG00000158125	-0.09786490288008909	[266]	[12,76,200]	-1	hSpCas9	negative selection	1717200
31377102	31377125	2	-	26627737	HCT116	viability after 6 days	GGCCCTTTGCTATGGTGGAATGG	XDH	ENSG00000158125	-0.568710093627931	[1020]	[133,93]	-3	hSpCas9	negative selection	1799510
31383084	31383107	2	+	26627737	HCT116	viability after 6 days	GCTTAGCAACAGCATCCACCAGG	XDH	ENSG00000158125	0.3394018531189599	[382]	[197,8]	2	hSpCas9	negative selection	1799511
31383754	31383777	2	-	26627737	HCT116	viability after 6 days	TCGGTAGAACATGGACCCGACGG	XDH	ENSG00000158125	0.7680612438570996	[457]	[159,101]	4	hSpCas9	negative selection	1799512
31397708	31397731	2	-	26627737	HCT116	viability after 6 days	GGAAATCTGTGCCGCTGCACAGG	XDH	ENSG00000158125	-1.1857964344227814	[479]	[76,8]	-6	hSpCas9	negative selection	1799513
31398634	31398657	2	+	26627737	HCT116	viability after 6 days	CATACTCATGACGATGCCAGGGG	XDH	ENSG00000158125	1.5641104096613738	[462]	[46,307]	7	hSpCas9	negative selection	1799514
31403109	31403132	2	-	26627737	HCT116	viability after 6 days	AACCAAGCTCGGCTGTGGAGAGG	XDH	ENSG00000158125	0.04310884554721761	[457]	[166,22]	0	hSpCas9	negative selection	1799515
31377102	31377125	2	-	26627737	HCT116	viability after 8 days	GGCCCTTTGCTATGGTGGAATGG	XDH	ENSG00000158125	0.4308093276622318	[281]	[243,174,209]	4	hSpCas9	negative selection	1881825
31383084	31383107	2	+	26627737	HCT116	viability after 8 days	GCTTAGCAACAGCATCCACCAGG	XDH	ENSG00000158125	0.9801979157046763	[183]	[261,126,211]	8	hSpCas9	negative selection	1881826
31383754	31383777	2	-	26627737	HCT116	viability after 8 days	TCGGTAGAACATGGACCCGACGG	XDH	ENSG00000158125	-0.15477873817332966	[191]	[80,120,82]	-2	hSpCas9	negative selection	1881827
31397708	31397731	2	-	26627737	HCT116	viability after 8 days	GGAAATCTGTGCCGCTGCACAGG	XDH	ENSG00000158125	0.5801829726840207	[176]	[134,135,165]	6	hSpCas9	negative selection	1881828
31398634	31398657	2	+	26627737	HCT116	viability after 8 days	CATACTCATGACGATGCCAGGGG	XDH	ENSG00000158125	-0.8928044097921173	[480]	[140,127,158]	-8	hSpCas9	negative selection	1881829
31403109	31403132	2	-	26627737	HCT116	viability after 8 days	AACCAAGCTCGGCTGTGGAGAGG	XDH	ENSG00000158125	0.3666610458054387	[241]	[139,183,190]	4	hSpCas9	negative selection	1881830
31377102	31377125	2	-	26627737	HCT116	viability after 9 days	GGCCCTTTGCTATGGTGGAATGG	XDH	ENSG00000158125	0.20525006920716715	[1020]	[339,293]	1	hSpCas9	negative selection	1964140
31383084	31383107	2	+	26627737	HCT116	viability after 9 days	GCTTAGCAACAGCATCCACCAGG	XDH	ENSG00000158125	1.3462070310240744	[382]	[402,146]	8	hSpCas9	negative selection	1964141
31383754	31383777	2	-	26627737	HCT116	viability after 9 days	TCGGTAGAACATGGACCCGACGG	XDH	ENSG00000158125	0.6622780094305076	[457]	[278,125]	5	hSpCas9	negative selection	1964142
31397708	31397731	2	-	26627737	HCT116	viability after 9 days	GGAAATCTGTGCCGCTGCACAGG	XDH	ENSG00000158125	-0.19582294315234489	[479]	[150,80]	-1	hSpCas9	negative selection	1964143
31398634	31398657	2	+	26627737	HCT116	viability after 9 days	CATACTCATGACGATGCCAGGGG	XDH	ENSG00000158125	-1.1185855951924084	[462]	[47,63]	-7	hSpCas9	negative selection	1964144
31403109	31403132	2	-	26627737	HCT116	viability after 9 days	AACCAAGCTCGGCTGTGGAGAGG	XDH	ENSG00000158125	1.0233325703672722	[457]	[99,365]	7	hSpCas9	negative selection	1964145
31377102	31377125	2	-	26627737	HCT116	viability after 12 days	GGCCCTTTGCTATGGTGGAATGG	XDH	ENSG00000158125	0.41452766556663234	[281]	[131,265,201]	4	hSpCas9	negative selection	2046455
31383084	31383107	2	+	26627737	HCT116	viability after 12 days	GCTTAGCAACAGCATCCACCAGG	XDH	ENSG00000158125	-0.0015130124193206695	[183]	[93,95,99]	0	hSpCas9	negative selection	2046456
31383754	31383777	2	-	26627737	HCT116	viability after 12 days	TCGGTAGAACATGGACCCGACGG	XDH	ENSG00000158125	0.11244520599086838	[191]	[44,196,92]	1	hSpCas9	negative selection	2046457
31397708	31397731	2	-	26627737	HCT116	viability after 12 days	GGAAATCTGTGCCGCTGCACAGG	XDH	ENSG00000158125	0.8093144366775985	[176]	[84,209,201]	7	hSpCas9	negative selection	2046458
31398634	31398657	2	+	26627737	HCT116	viability after 12 days	CATACTCATGACGATGCCAGGGG	XDH	ENSG00000158125	-0.5929369595131014	[480]	[215,104,175]	-6	hSpCas9	negative selection	2046459
31403109	31403132	2	-	26627737	HCT116	viability after 12 days	AACCAAGCTCGGCTGTGGAGAGG	XDH	ENSG00000158125	-0.3451734999997211	[241]	[100,88,109]	-4	hSpCas9	negative selection	2046460
31377102	31377125	2	-	26627737	HCT116	viability after 15 days	GGCCCTTTGCTATGGTGGAATGG	XDH	ENSG00000158125	1.28994047029935	[281]	[390,284,509]	8	hSpCas9	negative selection	2128770
31383084	31383107	2	+	26627737	HCT116	viability after 15 days	GCTTAGCAACAGCATCCACCAGG	XDH	ENSG00000158125	0.9953359959989274	[183]	[258,96,280]	8	hSpCas9	negative selection	2128771
31383754	31383777	2	-	26627737	HCT116	viability after 15 days	TCGGTAGAACATGGACCCGACGG	XDH	ENSG00000158125	0.33398680642287487	[191]	[141,191,83]	3	hSpCas9	negative selection	2128772
31397708	31397731	2	-	26627737	HCT116	viability after 15 days	GGAAATCTGTGCCGCTGCACAGG	XDH	ENSG00000158125	0.6639145566748802	[176]	[176,138,168]	6	hSpCas9	negative selection	2128773
31398634	31398657	2	+	26627737	HCT116	viability after 15 days	CATACTCATGACGATGCCAGGGG	XDH	ENSG00000158125	-0.9543620705471274	[480]	[141,175,109]	-7	hSpCas9	negative selection	2128774
31403109	31403132	2	-	26627737	HCT116	viability after 15 days	AACCAAGCTCGGCTGTGGAGAGG	XDH	ENSG00000158125	-0.7200112955834557	[241]	[106,74,73]	-6	hSpCas9	negative selection	2128775
31377102	31377125	2	-	26627737	HCT116	viability after 18 days	GGCCCTTTGCTATGGTGGAATGG	XDH	ENSG00000158125	0.44590371967499043	[281]	[141,101,324]	4	hSpCas9	negative selection	2211085
31383084	31383107	2	+	26627737	HCT116	viability after 18 days	GCTTAGCAACAGCATCCACCAGG	XDH	ENSG00000158125	1.375581290824679	[183]	[210,276,199]	8	hSpCas9	negative selection	2211086
31383754	31383777	2	-	26627737	HCT116	viability after 18 days	TCGGTAGAACATGGACCCGACGG	XDH	ENSG00000158125	0.342257176360845	[191]	[47,214,81]	3	hSpCas9	negative selection	2211087
31397708	31397731	2	-	26627737	HCT116	viability after 18 days	GGAAATCTGTGCCGCTGCACAGG	XDH	ENSG00000158125	0.9527237279219942	[176]	[215,160,117]	7	hSpCas9	negative selection	2211088
31398634	31398657	2	+	26627737	HCT116	viability after 18 days	CATACTCATGACGATGCCAGGGG	XDH	ENSG00000158125	-0.9335692510844831	[480]	[141,106,116]	-7	hSpCas9	negative selection	2211089
31403109	31403132	2	-	26627737	HCT116	viability after 18 days	AACCAAGCTCGGCTGTGGAGAGG	XDH	ENSG00000158125	-0.5161141489838308	[241]	[87,22,140]	-5	hSpCas9	negative selection	2211090
31412482	31412505	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGGGGTGGGGGGAGAGGGGAGGG	XDH	ENSG00000158125	1.0901125623731858	[0,9]	[0,3]	4	dCas9-VP64	positive selection	2394433
31375099	31375122	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACTGCAACCTCCACCTCCCGAG	XDH	ENSG00000158125	-1.4516426362223873	[480,182]	[29,20]	-8	dCas9-VP64	positive selection	2427033
31412482	31412505	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGGGGTGGGGGGAGAGGGGAGGG	XDH	ENSG00000158125	0.43603137209099274	[36,16]	[13,8]	3	dCas9-VP64	positive selection	2489688
31375099	31375122	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACTGCAACCTCCACCTCCCGAG	XDH	ENSG00000158125	1.047613524569726	[257,163]	[245,45]	6	dCas9-VP64	positive selection	2522288
31377188	31377211	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AATGTCATCTTCTCTCCGGGAGG	XDH	ENSG00000158125	0.091677520357062	[4,4]	[4,4]	2	hSpCas9	positive selection	3032771
31383063	31383086	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTTCCTGCCCAAAAGACAGAGG	XDH	ENSG00000158125	-0.244800474207298	[2,2]	[2,1]	-3	hSpCas9	positive selection	3032772
31397667	31397690	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGGCTTCCGGACCTTTGCCAGGG	XDH	ENSG00000158125	-0.3629366021043146	[4,4]	[3,2]	-5	hSpCas9	positive selection	3032773
31372384	31372407	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCATTCCAGGAGGTGCCCAAGGG	XDH	ENSG00000158125	-0.5727779779194992	[4,4]	[3,0]	-7	hSpCas9	positive selection	3032774
31377188	31377211	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AATGTCATCTTCTCTCCGGGAGG	XDH	ENSG00000158125	-0.08303751934214426	[4,4]	[3,2]	-1	hSpCas9	positive selection	3100629
31383063	31383086	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTTCCTGCCCAAAAGACAGAGG	XDH	ENSG00000158125	-0.43183496412973843	[2,2]	[2,0]	-6	hSpCas9	positive selection	3100630
31397667	31397690	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGGCTTCCGGACCTTTGCCAGGG	XDH	ENSG00000158125	-0.15584731846141808	[4,4]	[4,1]	-2	hSpCas9	positive selection	3100631
31372384	31372407	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCATTCCAGGAGGTGCCCAAGGG	XDH	ENSG00000158125	0.34464407645107675	[4,4]	[4,3]	6	hSpCas9	positive selection	3100632
31387837	31387860		-	24336571	A375	resistance to PLX after 7 days	CACGCCCCTGGATCCAACCCAGG	XDH	ENSG00000158125	-0.06286332917754056	[25,27]	[24,25]	-2	hSpCas9	positive selection	3155952
31388279	31388302		-	24336571	A375	resistance to PLX after 7 days	CTCTAGGATGGTGGATGCTGTGG	XDH	ENSG00000158125	-0.3724532617954897	[8,11]	[8,6]	-9	hSpCas9	positive selection	3155953
31387800	31387823		+	24336571	A375	resistance to PLX after 7 days	GCATCACCTACCAGCAACTCTGG	XDH	ENSG00000158125	0.019402369685188492	[6,10]	[10,6]	0	hSpCas9	positive selection	3155954
31387848	31387871		+	24336571	A375	resistance to PLX after 7 days	TCCAGGGGCGTGAACTCCTCTGG	XDH	ENSG00000158125	-0.4652959460655944	[16,17]	[12,11]	-9	hSpCas9	positive selection	3155955
31388223	31388246		+	24336571	A375	resistance to PLX after 7 days	TTACTGAGTGGTCTTTCTTCTGG	XDH	ENSG00000158125	0.4002448877349353	[15,18]	[21,23]	8	hSpCas9	positive selection	3155956
31387837	31387860		-	24336571	A375	resistance to PLX after 14 days	CACGCCCCTGGATCCAACCCAGG	XDH	ENSG00000158125	-0.4259241443955689	[30,28]	[9,9]	-5	hSpCas9	positive selection	3213745
31388279	31388302		-	24336571	A375	resistance to PLX after 14 days	CTCTAGGATGGTGGATGCTGTGG	XDH	ENSG00000158125	0.29893432581601703	[6,8]	[3,4]	3	hSpCas9	positive selection	3213746
31387800	31387823		+	24336571	A375	resistance to PLX after 14 days	GCATCACCTACCAGCAACTCTGG	XDH	ENSG00000158125	-0.5150724156954712	[8,12]	[3,2]	-6	hSpCas9	positive selection	3213747
31387848	31387871		+	24336571	A375	resistance to PLX after 14 days	TCCAGGGGCGTGAACTCCTCTGG	XDH	ENSG00000158125	-0.01133022285992713	[13,18]	[7,6]	0	hSpCas9	positive selection	3213748
31388223	31388246		+	24336571	A375	resistance to PLX after 14 days	TTACTGAGTGGTCTTTCTTCTGG	XDH	ENSG00000158125	1.232565640545058	[17,13]	[17,16]	8	hSpCas9	positive selection	3213749
31387837	31387860		-	24336571	A375	viability after 7 days	CACGCCCCTGGATCCAACCCAGG	XDH	ENSG00000158125	0.007325030582884473	[27]	[25,27]	0	hSpCas9	negative selection	3271538
31388279	31388302		-	24336571	A375	viability after 7 days	CTCTAGGATGGTGGATGCTGTGG	XDH	ENSG00000158125	0.17525258578460368	[9]	[8,11]	2	hSpCas9	negative selection	3271539
31387800	31387823		+	24336571	A375	viability after 7 days	GCATCACCTACCAGCAACTCTGG	XDH	ENSG00000158125	-0.35267094630149665	[11]	[6,10]	-5	hSpCas9	negative selection	3271540
31387848	31387871		+	24336571	A375	viability after 7 days	TCCAGGGGCGTGAACTCCTCTGG	XDH	ENSG00000158125	0.6203147230001874	[11]	[16,17]	8	hSpCas9	negative selection	3271541
31388223	31388246		+	24336571	A375	viability after 7 days	TTACTGAGTGGTCTTTCTTCTGG	XDH	ENSG00000158125	-0.15513686611571942	[20]	[15,18]	-2	hSpCas9	negative selection	3271542
31387837	31387860		-	24336571	A375	viability after 14 days	CACGCCCCTGGATCCAACCCAGG	XDH	ENSG00000158125	0.16864533694983375	[27]	[30,28]	2	hSpCas9	negative selection	3329331
31388279	31388302		-	24336571	A375	viability after 14 days	CTCTAGGATGGTGGATGCTGTGG	XDH	ENSG00000158125	-0.20411226093167373	[9]	[6,8]	-2	hSpCas9	negative selection	3329332
31387800	31387823		+	24336571	A375	viability after 14 days	GCATCACCTACCAGCAACTCTGG	XDH	ENSG00000158125	-0.0652522274319215	[11]	[8,12]	0	hSpCas9	negative selection	3329333
31387848	31387871		+	24336571	A375	viability after 14 days	TCCAGGGGCGTGAACTCCTCTGG	XDH	ENSG00000158125	0.56901958368479	[11]	[13,18]	7	hSpCas9	negative selection	3329334
31388223	31388246		+	24336571	A375	viability after 14 days	TTACTGAGTGGTCTTTCTTCTGG	XDH	ENSG00000158125	-0.27112497758858095	[20]	[17,13]	-3	hSpCas9	negative selection	3329335
31387800	31387823	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	GCATCACCTACCAGCAACTCTGG	XDH	ENSG00000158125	-1.6130385081375693	[467,467]	[0,0]	-9	hSpCas9	positive selection	3401641
31388223	31388246	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	TTACTGAGTGGTCTTTCTTCTGG	XDH	ENSG00000158125	-1.460350211620561	[420,420]	[0,0]	-8	hSpCas9	positive selection	3401642
31388279	31388302	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTCTAGGATGGTGGATGCTGTGG	XDH	ENSG00000158125	0.21293209208738176	[131,131]	[0,0]	1	hSpCas9	positive selection	3401643
31377187	31377210	2	+	26780180	HT29	viability (Avana library 4 designs)	AATGTCATCTTCTCTCCGGGAGG	XDH	ENSG00000158125	-0.204131845821595	[]	[]	-3	hSpCas9	negative selection	3472055
31383063	31383086	2	-	26780180	HT29	viability (Avana library 4 designs)	GCTTCCTGCCCAAAAGACAGAGG	XDH	ENSG00000158125	0.69549159614789	[]	[]	2	hSpCas9	negative selection	3472056
31397667	31397690	2	-	26780180	HT29	viability (Avana library 4 designs)	GGGCTTCCGGACCTTTGCCAGGG	XDH	ENSG00000158125	0.158536416449089	[]	[]	0	hSpCas9	negative selection	3472057
31372384	31372407	2	-	26780180	HT29	viability (Avana library 4 designs)	TCATTCCAGGAGGTGCCCAAGGG	XDH	ENSG00000158125	-0.00142570470264271	[]	[]	0	hSpCas9	negative selection	3472058
31383063	31383086	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTTCCTGCCCAAAAGACAGAGG	XDH	ENSG00000158125	0.709327116664991	[]	[]	1	hSpCas9	negative selection	3579160
31397667	31397690	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGGCTTCCGGACCTTTGCCAGGG	XDH	ENSG00000158125	5.49883834949931	[]	[]	8	hSpCas9	negative selection	3579161
31372384	31372407	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCATTCCAGGAGGTGCCCAAGGG	XDH	ENSG00000158125	5.64551214590898	[]	[]	8	hSpCas9	negative selection	3579162
31377187	31377210	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	AATGTCATCTTCTCTCCGGGAGG	XDH	ENSG00000158125	1.77942462307265	[]	[]	2	hSpCas9	negative selection	3579163
31387870	31387893	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTTTGAATAAAGATGGCGAGAGG	XDH	ENSG00000158125	2.79481535669878	[]	[]	4	hSpCas9	negative selection	3579164
31387806	31387829	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTTCCCCCAGAGTTGCTGGTAGG	XDH	ENSG00000158125	5.5756064994187	[]	[]	8	hSpCas9	negative selection	3579165
31383063	31383086	2	-	26780180	A375	viability (Avana lentiGuide)	GCTTCCTGCCCAAAAGACAGAGG	XDH	ENSG00000158125	-4.14775175718528	[]	[]	-7	hSpCas9	negative selection	3687819
31397667	31397690	2	-	26780180	A375	viability (Avana lentiGuide)	GGGCTTCCGGACCTTTGCCAGGG	XDH	ENSG00000158125	2.91995832498507	[]	[]	3	hSpCas9	negative selection	3687820
31372384	31372407	2	-	26780180	A375	viability (Avana lentiGuide)	TCATTCCAGGAGGTGCCCAAGGG	XDH	ENSG00000158125	-2.32580994908445	[]	[]	-4	hSpCas9	negative selection	3687821
31377187	31377210	2	+	26780180	A375	viability (Avana lentiGuide)	AATGTCATCTTCTCTCCGGGAGG	XDH	ENSG00000158125	-2.28704232436002	[]	[]	-4	hSpCas9	negative selection	3687822
31387870	31387893	2	+	26780180	A375	viability (Avana lentiGuide)	GTTTGAATAAAGATGGCGAGAGG	XDH	ENSG00000158125	-6.00768173139911	[]	[]	-8	hSpCas9	negative selection	3687823
31387806	31387829	2	-	26780180	A375	viability (Avana lentiGuide)	TTTCCCCCAGAGTTGCTGGTAGG	XDH	ENSG00000158125	-3.55917455946084	[]	[]	-6	hSpCas9	negative selection	3687824
31383063	31383086	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTTCCTGCCCAAAAGACAGAGG	XDH	ENSG00000158125	-0.14199694892419373	[4]	[4,3]	-2	hSpCas9	positive selection	3796426
31397667	31397690	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGGCTTCCGGACCTTTGCCAGGG	XDH	ENSG00000158125	0.1055312822993689	[5]	[7,4]	2	hSpCas9	positive selection	3796427
31372384	31372407	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCATTCCAGGAGGTGCCCAAGGG	XDH	ENSG00000158125	0.07102650307715733	[5]	[5,6]	1	hSpCas9	positive selection	3796428
31377187	31377210	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AATGTCATCTTCTCTCCGGGAGG	XDH	ENSG00000158125	0.17670026922824283	[5]	[6,6]	5	hSpCas9	positive selection	3796429
31387870	31387893	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTTGAATAAAGATGGCGAGAGG	XDH	ENSG00000158125	0.06934415128553136	[5]	[5,5]	1	hSpCas9	positive selection	3796430
31387806	31387829	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTTCCCCCAGAGTTGCTGGTAGG	XDH	ENSG00000158125	0.36950509695551165	[5]	[6,6]	9	hSpCas9	positive selection	3796431
31383063	31383086	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTTCCTGCCCAAAAGACAGAGG	XDH	ENSG00000158125	0.10605870829679066	[4]	[3,4]	2	hSpCas9	positive selection	3905033
31397667	31397690	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGGCTTCCGGACCTTTGCCAGGG	XDH	ENSG00000158125	-0.20715073131744977	[6]	[4,4]	-3	hSpCas9	positive selection	3905034
31372384	31372407	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCATTCCAGGAGGTGCCCAAGGG	XDH	ENSG00000158125	0.13838456638917865	[5]	[5,5]	3	hSpCas9	positive selection	3905035
31377187	31377210	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AATGTCATCTTCTCTCCGGGAGG	XDH	ENSG00000158125	0.2275934780929977	[6]	[6,6]	6	hSpCas9	positive selection	3905036
31387870	31387893	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTTGAATAAAGATGGCGAGAGG	XDH	ENSG00000158125	0.1401852424197611	[5]	[5,4]	3	hSpCas9	positive selection	3905037
31387806	31387829	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTTCCCCCAGAGTTGCTGGTAGG	XDH	ENSG00000158125	0.3083332920755245	[6]	[6,6]	8	hSpCas9	positive selection	3905038
31386421	31386444	2	+	26780180	A375	viability	CGTGTTCCCCACGACCAGCTTGG	XDH	ENSG00000158125	0.0751146492681373	[]	[]	0	hSpCas9	negative selection	4013085
31388279	31388302	2	-	26780180	A375	viability	CTCTAGGATGGTGGATGCTGTGG	XDH	ENSG00000158125	0.960992072998093	[]	[]	4	hSpCas9	negative selection	4013086
31387800	31387823	2	+	26780180	A375	viability	GCATCACCTACCAGCAACTCTGG	XDH	ENSG00000158125	1.52530406940304	[]	[]	8	hSpCas9	negative selection	4013087
31386518	31386541	2	+	26780180	A375	viability	TCAAATCGCAGCTGCTTCCGAGG	XDH	ENSG00000158125	1.19260887788043	[]	[]	6	hSpCas9	negative selection	4013088
31387848	31387871	2	+	26780180	A375	viability	TCCAGGGGCGTGAACTCCTCTGG	XDH	ENSG00000158125	1.23288514411687	[]	[]	6	hSpCas9	negative selection	4013089
31388223	31388246	2	+	26780180	A375	viability	TTACTGAGTGGTCTTTCTTCTGG	XDH	ENSG00000158125	0.539230794137289	[]	[]	1	hSpCas9	negative selection	4013090
31386421	31386444	2	+	26780180	HT29	viability (GeCKOv2 library)	CGTGTTCCCCACGACCAGCTTGG	XDH	ENSG00000158125	0.620299167905195	[]	[]	2	hSpCas9	negative selection	4121051
31388279	31388302	2	-	26780180	HT29	viability (GeCKOv2 library)	CTCTAGGATGGTGGATGCTGTGG	XDH	ENSG00000158125	1.13046558239948	[]	[]	5	hSpCas9	negative selection	4121052
31387800	31387823	2	+	26780180	HT29	viability (GeCKOv2 library)	GCATCACCTACCAGCAACTCTGG	XDH	ENSG00000158125	0.741179334918314	[]	[]	3	hSpCas9	negative selection	4121053
31386518	31386541	2	+	26780180	HT29	viability (GeCKOv2 library)	TCAAATCGCAGCTGCTTCCGAGG	XDH	ENSG00000158125	0.650557249547416	[]	[]	2	hSpCas9	negative selection	4121054
31387848	31387871	2	+	26780180	HT29	viability (GeCKOv2 library)	TCCAGGGGCGTGAACTCCTCTGG	XDH	ENSG00000158125	1.56316181711177	[]	[]	8	hSpCas9	negative selection	4121055
31388223	31388246	2	+	26780180	HT29	viability (GeCKOv2 library)	TTACTGAGTGGTCTTTCTTCTGG	XDH	ENSG00000158125	0.64048774822811	[]	[]	2	hSpCas9	negative selection	4121056
31387837	31387860	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CACGCCCCTGGATCCAACCCAGG	XDH	ENSG00000158125	-0.034546985184069734	[4]	[2,3]	-1	hSpCas9	positive selection	4182800
31388279	31388302	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTCTAGGATGGTGGATGCTGTGG	XDH	ENSG00000158125	-0.2680206465234316	[3]	[1,1]	-6	hSpCas9	positive selection	4182801
31387800	31387823	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCATCACCTACCAGCAACTCTGG	XDH	ENSG00000158125	-0.1799178500082817	[3]	[1,1]	-4	hSpCas9	positive selection	4182802
31387848	31387871	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCCAGGGGCGTGAACTCCTCTGG	XDH	ENSG00000158125	0.016298449066336082	[3]	[1,2]	0	hSpCas9	positive selection	4182803
31388223	31388246	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTACTGAGTGGTCTTTCTTCTGG	XDH	ENSG00000158125	0.4944447197386436	[4]	[3,4]	9	hSpCas9	positive selection	4182804
31387837	31387860	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CACGCCCCTGGATCCAACCCAGG	XDH	ENSG00000158125	1.1151792598658057	[4]	[3,4,4,4]	8	hSpCas9	positive selection	4246822
31388279	31388302	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTCTAGGATGGTGGATGCTGTGG	XDH	ENSG00000158125	0.31413911760770996	[2]	[1,2,2,0]	2	hSpCas9	positive selection	4246823
31387800	31387823	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCATCACCTACCAGCAACTCTGG	XDH	ENSG00000158125	-0.22832554602363966	[2]	[2,0,0,0]	-3	hSpCas9	positive selection	4246824
31387848	31387871	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCCAGGGGCGTGAACTCCTCTGG	XDH	ENSG00000158125	-0.09828268924093636	[3]	[3,0,0,0]	-1	hSpCas9	positive selection	4246825
31388223	31388246	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTACTGAGTGGTCTTTCTTCTGG	XDH	ENSG00000158125	0.0822517352250961	[4]	[4,3,1,0]	0	hSpCas9	positive selection	4246826
31386518	31386541	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCAAATCGCAGCTGCTTCCGAGG	XDH	ENSG00000158125	0.05819372246984912	[2]	[2,1]	1	hSpCas9	positive selection	4308119
31386421	31386444	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGTGTTCCCCACGACCAGCTTGG	XDH	ENSG00000158125	0.40873460709009307	[4]	[4,4]	8	hSpCas9	positive selection	4308120
31387848	31387871	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCAGGGGCGTGAACTCCTCTGG	XDH	ENSG00000158125	0.13511799812445768	[3]	[2,2]	2	hSpCas9	positive selection	4308121
31387800	31387823	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCATCACCTACCAGCAACTCTGG	XDH	ENSG00000158125	-0.17864425266943293	[4]	[3,1]	-4	hSpCas9	positive selection	4372366
31388223	31388246	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTACTGAGTGGTCTTTCTTCTGG	XDH	ENSG00000158125	-0.05188752239778571	[3]	[4,1]	-1	hSpCas9	positive selection	4372367
31388279	31388302	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCTAGGATGGTGGATGCTGTGG	XDH	ENSG00000158125	0.12475316239487108	[2]	[2,2]	2	hSpCas9	positive selection	4372368
31372222	31372244	2	+	27760321	OCIAML3	viability	ACTCACTTGATCTTGGCGTGGG	XDH	ENSG00000158125	0.4321734114401904	[841,745]	[766,926]	5	hSpCas9	negative selection	4454532
31377188	31377210	2	+	27760321	OCIAML3	viability	ATGTCATCTTCTCTCCGGGAGG	XDH	ENSG00000158125	0.4388770111136169	[817,707]	[577,1104]	5	hSpCas9	negative selection	4454533
31383767	31383789	2	+	27760321	OCIAML3	viability	GTTCTACCGAATTCAGCTCAGG	XDH	ENSG00000158125	0.14398230825950525	[649,584]	[549,510]	1	hSpCas9	negative selection	4454534
31386429	31386451	2	-	27760321	OCIAML3	viability	CCTGACGCCAAGCTGGTCGTGG	XDH	ENSG00000158125	0.6443955005661663	[835,704]	[825,1084]	7	hSpCas9	negative selection	4454535
31398634	31398656	2	+	27760321	OCIAML3	viability	CATACTCATGACGATGCCAGGG	XDH	ENSG00000158125	0.36600206392250323	[495,405]	[424,487]	4	hSpCas9	negative selection	4454536
31372222	31372244	2	+	27760321	OCIAML2	viability	ACTCACTTGATCTTGGCGTGGG	XDH	ENSG00000158125	0.09056008038692787	[841,745]	[589,804]	1	hSpCas9	negative selection	4537995
31377188	31377210	2	+	27760321	OCIAML2	viability	ATGTCATCTTCTCTCCGGGAGG	XDH	ENSG00000158125	0.5943819483331785	[817,707]	[881,991]	7	hSpCas9	negative selection	4537996
31383767	31383789	2	+	27760321	OCIAML2	viability	GTTCTACCGAATTCAGCTCAGG	XDH	ENSG00000158125	0.19753342789849643	[649,584]	[453,727]	2	hSpCas9	negative selection	4537997
31386429	31386451	2	-	27760321	OCIAML2	viability	CCTGACGCCAAGCTGGTCGTGG	XDH	ENSG00000158125	0.31870685569141743	[835,704]	[635,956]	4	hSpCas9	negative selection	4537998
31398634	31398656	2	+	27760321	OCIAML2	viability	CATACTCATGACGATGCCAGGG	XDH	ENSG00000158125	0.33663391873103343	[495,405]	[369,574]	4	hSpCas9	negative selection	4537999
31372222	31372244	2	+	27760321	MV411	viability	ACTCACTTGATCTTGGCGTGGG	XDH	ENSG00000158125	1.3559720475479389	[841,745]	[1495,1102]	8	hSpCas9	negative selection	4621458
31377188	31377210	2	+	27760321	MV411	viability	ATGTCATCTTCTCTCCGGGAGG	XDH	ENSG00000158125	0.9078158931737679	[817,707]	[928,961]	6	hSpCas9	negative selection	4621459
31383767	31383789	2	+	27760321	MV411	viability	GTTCTACCGAATTCAGCTCAGG	XDH	ENSG00000158125	0.22063155369675586	[649,584]	[391,597]	1	hSpCas9	negative selection	4621460
31386429	31386451	2	-	27760321	MV411	viability	CCTGACGCCAAGCTGGTCGTGG	XDH	ENSG00000158125	1.8411312293855437	[835,704]	[2312,1066]	9	hSpCas9	negative selection	4621461
31398634	31398656	2	+	27760321	MV411	viability	CATACTCATGACGATGCCAGGG	XDH	ENSG00000158125	0.5571134490980226	[495,405]	[362,544]	4	hSpCas9	negative selection	4621462
31372222	31372244	2	+	27760321	HL60	viability	ACTCACTTGATCTTGGCGTGGG	XDH	ENSG00000158125	0.38763300588352656	[841,745]	[717,983]	5	hSpCas9	negative selection	4704921
31377188	31377210	2	+	27760321	HL60	viability	ATGTCATCTTCTCTCCGGGAGG	XDH	ENSG00000158125	0.6412167535509516	[817,707]	[1069,862]	7	hSpCas9	negative selection	4704922
31383767	31383789	2	+	27760321	HL60	viability	GTTCTACCGAATTCAGCTCAGG	XDH	ENSG00000158125	0.2774249001869194	[649,584]	[568,654]	3	hSpCas9	negative selection	4704923
31386429	31386451	2	-	27760321	HL60	viability	CCTGACGCCAAGCTGGTCGTGG	XDH	ENSG00000158125	0.3078995151429882	[835,704]	[784,766]	4	hSpCas9	negative selection	4704924
31398634	31398656	2	+	27760321	HL60	viability	CATACTCATGACGATGCCAGGG	XDH	ENSG00000158125	-0.31189248853419616	[495,405]	[355,230]	-4	hSpCas9	negative selection	4704925
31372222	31372244	2	+	27760321	HT1080	viability	ACTCACTTGATCTTGGCGTGGG	XDH	ENSG00000158125	0.26907407867355637	[745,581]	[344,289]	1	hSpCas9	negative selection	4788384
31377188	31377210	2	+	27760321	HT1080	viability	ATGTCATCTTCTCTCCGGGAGG	XDH	ENSG00000158125	0.006787565636693471	[707,552]	[217,289]	0	hSpCas9	negative selection	4788385
31383767	31383789	2	+	27760321	HT1080	viability	GTTCTACCGAATTCAGCTCAGG	XDH	ENSG00000158125	0.6945370140680244	[584,456]	[312,360]	4	hSpCas9	negative selection	4788386
31386429	31386451	2	-	27760321	HT1080	viability	CCTGACGCCAAGCTGGTCGTGG	XDH	ENSG00000158125	0.9051765165081224	[704,549]	[312,637]	5	hSpCas9	negative selection	4788387
31398634	31398656	2	+	27760321	HT1080	viability	CATACTCATGACGATGCCAGGG	XDH	ENSG00000158125	0.45814179148925	[405,316]	[183,212]	2	hSpCas9	negative selection	4788388
31372222	31372244	2	+	27760321	HT29	viability after 7 days	ACTCACTTGATCTTGGCGTGGG	XDH	ENSG00000158125	-0.32270468602221813	[745,581]	[713,614,720]	-4	hSpCas9	negative selection	4871847
31377188	31377210	2	+	27760321	HT29	viability after 7 days	ATGTCATCTTCTCTCCGGGAGG	XDH	ENSG00000158125	0.09528477252039713	[707,552]	[812,1123,658]	1	hSpCas9	negative selection	4871848
31383767	31383789	2	+	27760321	HT29	viability after 7 days	GTTCTACCGAATTCAGCTCAGG	XDH	ENSG00000158125	-0.38758162137650487	[584,456]	[625,485,441]	-5	hSpCas9	negative selection	4871849
31386429	31386451	2	-	27760321	HT29	viability after 7 days	CCTGACGCCAAGCTGGTCGTGG	XDH	ENSG00000158125	0.2629799511923995	[704,549]	[1026,1003,882]	4	hSpCas9	negative selection	4871850
31398634	31398656	2	+	27760321	HT29	viability after 7 days	CATACTCATGACGATGCCAGGG	XDH	ENSG00000158125	-0.0526054654684872	[405,316]	[505,395,449]	0	hSpCas9	negative selection	4871851
31372222	31372244	2	+	27760321	HT29	viability after 25 days	ACTCACTTGATCTTGGCGTGGG	XDH	ENSG00000158125	-0.07711228603835929	[745,581]	[542,827,805]	-1	hSpCas9	negative selection	4955310
31377188	31377210	2	+	27760321	HT29	viability after 25 days	ATGTCATCTTCTCTCCGGGAGG	XDH	ENSG00000158125	0.2132219178856989	[707,552]	[1094,785,580]	2	hSpCas9	negative selection	4955311
31383767	31383789	2	+	27760321	HT29	viability after 25 days	GTTCTACCGAATTCAGCTCAGG	XDH	ENSG00000158125	0.14037944499921506	[584,456]	[530,734,715]	1	hSpCas9	negative selection	4955312
31386429	31386451	2	-	27760321	HT29	viability after 25 days	CCTGACGCCAAGCTGGTCGTGG	XDH	ENSG00000158125	0.5169592346136788	[704,549]	[916,689,1528]	6	hSpCas9	negative selection	4955313
31398634	31398656	2	+	27760321	HT29	viability after 25 days	CATACTCATGACGATGCCAGGG	XDH	ENSG00000158125	0.45520401619550005	[405,316]	[532,449,734]	5	hSpCas9	negative selection	4955314
31372222	31372244	2	+	27760321	HT29	viability after 22 days	ACTCACTTGATCTTGGCGTGGG	XDH	ENSG00000158125	-0.052510357546292186	[745,581]	[645,836,739]	0	hSpCas9	negative selection	5038773
31377188	31377210	2	+	27760321	HT29	viability after 22 days	ATGTCATCTTCTCTCCGGGAGG	XDH	ENSG00000158125	0.15273841193366644	[707,552]	[491,1090,856]	1	hSpCas9	negative selection	5038774
31383767	31383789	2	+	27760321	HT29	viability after 22 days	GTTCTACCGAATTCAGCTCAGG	XDH	ENSG00000158125	0.07210473297629205	[584,456]	[784,632,475]	0	hSpCas9	negative selection	5038775
31386429	31386451	2	-	27760321	HT29	viability after 22 days	CCTGACGCCAAGCTGGTCGTGG	XDH	ENSG00000158125	0.48073091706250437	[704,549]	[873,995,1171]	5	hSpCas9	negative selection	5038776
31398634	31398656	2	+	27760321	HT29	viability after 22 days	CATACTCATGACGATGCCAGGG	XDH	ENSG00000158125	0.4241954211565921	[405,316]	[586,596,496]	4	hSpCas9	negative selection	5038777
31372222	31372244	2	+	27760321	HT29	viability after 19 days	ACTCACTTGATCTTGGCGTGGG	XDH	ENSG00000158125	-0.14355608496760486	[745,581]	[569,748,728]	-1	hSpCas9	negative selection	5122236
31377188	31377210	2	+	27760321	HT29	viability after 19 days	ATGTCATCTTCTCTCCGGGAGG	XDH	ENSG00000158125	0.42890180766592945	[707,552]	[1115,1003,812]	4	hSpCas9	negative selection	5122237
31383767	31383789	2	+	27760321	HT29	viability after 19 days	GTTCTACCGAATTCAGCTCAGG	XDH	ENSG00000158125	-0.023785342044032598	[584,456]	[782,284,705]	0	hSpCas9	negative selection	5122238
31386429	31386451	2	-	27760321	HT29	viability after 19 days	CCTGACGCCAAGCTGGTCGTGG	XDH	ENSG00000158125	0.7233048172282702	[704,549]	[955,1264,1303]	7	hSpCas9	negative selection	5122239
31398634	31398656	2	+	27760321	HT29	viability after 19 days	CATACTCATGACGATGCCAGGG	XDH	ENSG00000158125	0.7434159023216717	[405,316]	[628,709,728]	7	hSpCas9	negative selection	5122240
31372222	31372244	2	+	27760321	HT29	viability after 16 days	ACTCACTTGATCTTGGCGTGGG	XDH	ENSG00000158125	0.06511455682462175	[745,581]	[733,864,725]	0	hSpCas9	negative selection	5205699
31377188	31377210	2	+	27760321	HT29	viability after 16 days	ATGTCATCTTCTCTCCGGGAGG	XDH	ENSG00000158125	-0.027252500993995565	[707,552]	[676,736,659]	0	hSpCas9	negative selection	5205700
31383767	31383789	2	+	27760321	HT29	viability after 16 days	GTTCTACCGAATTCAGCTCAGG	XDH	ENSG00000158125	-0.31342881928720134	[584,456]	[573,435,407]	-3	hSpCas9	negative selection	5205701
31386429	31386451	2	-	27760321	HT29	viability after 16 days	CCTGACGCCAAGCTGGTCGTGG	XDH	ENSG00000158125	0.5361455084487404	[704,549]	[914,1099,1026]	6	hSpCas9	negative selection	5205702
31398634	31398656	2	+	27760321	HT29	viability after 16 days	CATACTCATGACGATGCCAGGG	XDH	ENSG00000158125	0.5987024526086613	[405,316]	[633,589,615]	7	hSpCas9	negative selection	5205703
31372222	31372244	2	+	27760321	HT29	viability after 13 days	ACTCACTTGATCTTGGCGTGGG	XDH	ENSG00000158125	-0.3649966208166159	[745,581]	[504,700,588]	-4	hSpCas9	negative selection	5289162
31377188	31377210	2	+	27760321	HT29	viability after 13 days	ATGTCATCTTCTCTCCGGGAGG	XDH	ENSG00000158125	0.3723775081190235	[707,552]	[1228,751,863]	5	hSpCas9	negative selection	5289163
31383767	31383789	2	+	27760321	HT29	viability after 13 days	GTTCTACCGAATTCAGCTCAGG	XDH	ENSG00000158125	-0.215408817415904	[584,456]	[641,373,543]	-3	hSpCas9	negative selection	5289164
31386429	31386451	2	-	27760321	HT29	viability after 13 days	CCTGACGCCAAGCTGGTCGTGG	XDH	ENSG00000158125	0.512077724229704	[704,549]	[996,937,1170]	6	hSpCas9	negative selection	5289165
31398634	31398656	2	+	27760321	HT29	viability after 13 days	CATACTCATGACGATGCCAGGG	XDH	ENSG00000158125	0.26146800964049355	[405,316]	[548,473,485]	3	hSpCas9	negative selection	5289166
31372222	31372244	2	+	27760321	HT29	viability after 10 days	ACTCACTTGATCTTGGCGTGGG	XDH	ENSG00000158125	-0.16235972518123887	[745,581]	[613,772,833]	-2	hSpCas9	negative selection	5372625
31377188	31377210	2	+	27760321	HT29	viability after 10 days	ATGTCATCTTCTCTCCGGGAGG	XDH	ENSG00000158125	-0.08437999963280185	[707,552]	[792,850,589]	-1	hSpCas9	negative selection	5372626
31383767	31383789	2	+	27760321	HT29	viability after 10 days	GTTCTACCGAATTCAGCTCAGG	XDH	ENSG00000158125	0.2324608236493898	[584,456]	[829,720,740]	3	hSpCas9	negative selection	5372627
31386429	31386451	2	-	27760321	HT29	viability after 10 days	CCTGACGCCAAGCTGGTCGTGG	XDH	ENSG00000158125	0.3666667188102678	[704,549]	[1163,774,1082]	5	hSpCas9	negative selection	5372628
31398634	31398656	2	+	27760321	HT29	viability after 10 days	CATACTCATGACGATGCCAGGG	XDH	ENSG00000158125	0.4893911358937523	[405,316]	[641,592,663]	6	hSpCas9	negative selection	5372629
31372222	31372244	2	+	27760321	MOLM13	viability	ACTCACTTGATCTTGGCGTGGG	XDH	ENSG00000158125	0.39368759844224266	[841,745]	[882,335]	2	hSpCas9	negative selection	5456088
31377188	31377210	2	+	27760321	MOLM13	viability	ATGTCATCTTCTCTCCGGGAGG	XDH	ENSG00000158125	1.0137912235987496	[817,707]	[860,871]	7	hSpCas9	negative selection	5456089
31383767	31383789	2	+	27760321	MOLM13	viability	GTTCTACCGAATTCAGCTCAGG	XDH	ENSG00000158125	-0.02439009679281323	[649,584]	[426,269]	0	hSpCas9	negative selection	5456090
31386429	31386451	2	-	27760321	MOLM13	viability	CCTGACGCCAAGCTGGTCGTGG	XDH	ENSG00000158125	-0.15480105403206557	[835,704]	[253,503]	-1	hSpCas9	negative selection	5456091
31398634	31398656	2	+	27760321	MOLM13	viability	CATACTCATGACGATGCCAGGG	XDH	ENSG00000158125	0.772852757603336	[495,405]	[450,416]	5	hSpCas9	negative selection	5456092
31414674	31414697	2	+	27661255	K562	viability	GGTTGGGGTCCCCGAACTCCAGG	XDH	ENSG00000158125	0.423852035740462	[418,460]	[528,420]	9	dCas9-KRAB	negative selection	5523149
31386518	31386541	2	+	27260156	BXPC3	viability	TCAAATCGCAGCTGCTTCCGAGG	XDH	ENSG00000158125	0.48642362436369124	[331]	[423,472,475,588]	8	hSpCas9	negative selection	5580579
31386421	31386444	2	+	27260156	BXPC3	viability	CGTGTTCCCCACGACCAGCTTGG	XDH	ENSG00000158125	0.33921009674272184	[1103]	[1442,1359,1458,1592]	7	hSpCas9	negative selection	5580580
31387848	31387871	2	+	27260156	BXPC3	viability	TCCAGGGGCGTGAACTCCTCTGG	XDH	ENSG00000158125	0.20319927861943235	[497]	[570,562,542,737]	4	hSpCas9	negative selection	5580581
31387800	31387823	2	+	27260156	BXPC3	viability	GCATCACCTACCAGCAACTCTGG	XDH	ENSG00000158125	0.10891897557259211	[1112]	[1163,1290,1084,1506]	2	hSpCas9	negative selection	5644826
31388223	31388246	2	+	27260156	BXPC3	viability	TTACTGAGTGGTCTTTCTTCTGG	XDH	ENSG00000158125	0.10366908932023944	[981]	[1013,899,1214,1327]	2	hSpCas9	negative selection	5644827
31388279	31388302	2	-	27260156	BXPC3	viability	CTCTAGGATGGTGGATGCTGTGG	XDH	ENSG00000158125	-0.025162557784497108	[384]	[392,307,487,397]	0	hSpCas9	negative selection	5644828
31386518	31386541	2	+	27260156	A673	viability	TCAAATCGCAGCTGCTTCCGAGG	XDH	ENSG00000158125	0.6088989563762683	[331]	[574,525,601,732]	9	hSpCas9	negative selection	5701830
31386421	31386444	2	+	27260156	A673	viability	CGTGTTCCCCACGACCAGCTTGG	XDH	ENSG00000158125	0.3951595310928331	[1103]	[1755,1766,1789,1651]	8	hSpCas9	negative selection	5701831
31387848	31387871	2	+	27260156	A673	viability	TCCAGGGGCGTGAACTCCTCTGG	XDH	ENSG00000158125	0.1434305539332015	[497]	[800,477,589,800]	3	hSpCas9	negative selection	5701832
31387800	31387823	2	+	27260156	A673	viability	GCATCACCTACCAGCAACTCTGG	XDH	ENSG00000158125	0.0133315987174214	[1112]	[1496,1246,1240,1432]	0	hSpCas9	negative selection	5766077
31388223	31388246	2	+	27260156	A673	viability	TTACTGAGTGGTCTTTCTTCTGG	XDH	ENSG00000158125	0.036111171486709726	[981]	[1303,1012,1156,1385]	0	hSpCas9	negative selection	5766078
31388279	31388302	2	-	27260156	A673	viability	CTCTAGGATGGTGGATGCTGTGG	XDH	ENSG00000158125	-0.05978777040006883	[384]	[430,422,444,474]	-1	hSpCas9	negative selection	5766079
31386518	31386541	2	+	27260156	A375	viability	TCAAATCGCAGCTGCTTCCGAGG	XDH	ENSG00000158125	0.12744805037938162	[331]	[266,726,410,338]	1	hSpCas9	negative selection	5823081
31386421	31386444	2	+	27260156	A375	viability	CGTGTTCCCCACGACCAGCTTGG	XDH	ENSG00000158125	0.4156264615684524	[1103]	[1779,1960,1490,1679]	6	hSpCas9	negative selection	5823082
31387848	31387871	2	+	27260156	A375	viability	TCCAGGGGCGTGAACTCCTCTGG	XDH	ENSG00000158125	0.4458058109986879	[497]	[645,980,742,817]	6	hSpCas9	negative selection	5823083
31387800	31387823	2	+	27260156	A375	viability	GCATCACCTACCAGCAACTCTGG	XDH	ENSG00000158125	-0.02322707407686475	[1112]	[1483,1434,1213,1031]	0	hSpCas9	negative selection	5887328
31388223	31388246	2	+	27260156	A375	viability	TTACTGAGTGGTCTTTCTTCTGG	XDH	ENSG00000158125	0.38925308364947475	[981]	[1642,1856,1297,1281]	5	hSpCas9	negative selection	5887329
31388279	31388302	2	-	27260156	A375	viability	CTCTAGGATGGTGGATGCTGTGG	XDH	ENSG00000158125	-0.36104566506651276	[384]	[346,322,436,294]	-5	hSpCas9	negative selection	5887330
31386518	31386541	2	+	27260156	COLO741	viability	TCAAATCGCAGCTGCTTCCGAGG	XDH	ENSG00000158125	0.35930728838154424	[331]	[534,571,524]	7	hSpCas9	negative selection	5944332
31386421	31386444	2	+	27260156	COLO741	viability	CGTGTTCCCCACGACCAGCTTGG	XDH	ENSG00000158125	0.3802926589814357	[1103]	[2018,2010,1513]	7	hSpCas9	negative selection	5944333
31387848	31387871	2	+	27260156	COLO741	viability	TCCAGGGGCGTGAACTCCTCTGG	XDH	ENSG00000158125	-0.09892881698818884	[497]	[768,480,548]	-2	hSpCas9	negative selection	5944334
31387800	31387823	2	+	27260156	COLO741	viability	GCATCACCTACCAGCAACTCTGG	XDH	ENSG00000158125	0.17078556767783648	[1112]	[1843,1611,1379]	3	hSpCas9	negative selection	6008579
31388223	31388246	2	+	27260156	COLO741	viability	TTACTGAGTGGTCTTTCTTCTGG	XDH	ENSG00000158125	0.4119046615867925	[981]	[1719,1752,1544]	8	hSpCas9	negative selection	6008580
31388279	31388302	2	-	27260156	COLO741	viability	CTCTAGGATGGTGGATGCTGTGG	XDH	ENSG00000158125	0.03261274667639846	[384]	[594,501,424]	0	hSpCas9	negative selection	6008581
31386518	31386541	2	+	27260156	CAL120	viability	TCAAATCGCAGCTGCTTCCGAGG	XDH	ENSG00000158125	0.3416049700716389	[331]	[595,504,480]	5	hSpCas9	negative selection	6065583
31386421	31386444	2	+	27260156	CAL120	viability	CGTGTTCCCCACGACCAGCTTGG	XDH	ENSG00000158125	0.6679058439423244	[1103]	[2713,2233,1687]	8	hSpCas9	negative selection	6065584
31387848	31387871	2	+	27260156	CAL120	viability	TCCAGGGGCGTGAACTCCTCTGG	XDH	ENSG00000158125	-0.13886587515453203	[497]	[764,463,490]	-2	hSpCas9	negative selection	6065585
31387800	31387823	2	+	27260156	CAL120	viability	GCATCACCTACCAGCAACTCTGG	XDH	ENSG00000158125	-0.11694072986893933	[1112]	[1521,1246,1101]	-2	hSpCas9	negative selection	6129830
31388223	31388246	2	+	27260156	CAL120	viability	TTACTGAGTGGTCTTTCTTCTGG	XDH	ENSG00000158125	0.40385898807820264	[981]	[1875,1643,1372]	6	hSpCas9	negative selection	6129831
31388279	31388302	2	-	27260156	CAL120	viability	CTCTAGGATGGTGGATGCTGTGG	XDH	ENSG00000158125	-0.18191993676073948	[384]	[350,477,426]	-3	hSpCas9	negative selection	6129832
31386518	31386541	2	+	27260156	CADOES1	viability	TCAAATCGCAGCTGCTTCCGAGG	XDH	ENSG00000158125	0.2393311675904617	[331]	[382,461,252,359]	4	hSpCas9	negative selection	6186834
31386421	31386444	2	+	27260156	CADOES1	viability	CGTGTTCCCCACGACCAGCTTGG	XDH	ENSG00000158125	0.45768427203502204	[1103]	[1313,1453,1533,1335]	7	hSpCas9	negative selection	6186835
31387848	31387871	2	+	27260156	CADOES1	viability	TCCAGGGGCGTGAACTCCTCTGG	XDH	ENSG00000158125	0.06352389970196903	[497]	[649,372,413,498]	1	hSpCas9	negative selection	6186836
31387800	31387823	2	+	27260156	CADOES1	viability	GCATCACCTACCAGCAACTCTGG	XDH	ENSG00000158125	0.16289143177880128	[1112]	[1228,905,1080,1428]	3	hSpCas9	negative selection	6251081
31388223	31388246	2	+	27260156	CADOES1	viability	TTACTGAGTGGTCTTTCTTCTGG	XDH	ENSG00000158125	0.27701410412849703	[981]	[1102,1196,760,1375]	4	hSpCas9	negative selection	6251082
31388279	31388302	2	-	27260156	CADOES1	viability	CTCTAGGATGGTGGATGCTGTGG	XDH	ENSG00000158125	-0.09894016937090355	[384]	[369,235,295,438]	-2	hSpCas9	negative selection	6251083
31386518	31386541	2	+	27260156	EWS502	viability	TCAAATCGCAGCTGCTTCCGAGG	XDH	ENSG00000158125	0.07002367380081531	[331]	[394,460,376,224]	1	hSpCas9	negative selection	6308085
31386421	31386444	2	+	27260156	EWS502	viability	CGTGTTCCCCACGACCAGCTTGG	XDH	ENSG00000158125	0.2963135762383773	[1103]	[1120,1335,1746,1591]	5	hSpCas9	negative selection	6308086
31387848	31387871	2	+	27260156	EWS502	viability	TCCAGGGGCGTGAACTCCTCTGG	XDH	ENSG00000158125	0.4396422947490638	[497]	[594,667,720,904]	7	hSpCas9	negative selection	6308087
31387800	31387823	2	+	27260156	EWS502	viability	GCATCACCTACCAGCAACTCTGG	XDH	ENSG00000158125	-0.02205377635601824	[1112]	[915,1190,1166,1411]	0	hSpCas9	negative selection	6372332
31388223	31388246	2	+	27260156	EWS502	viability	TTACTGAGTGGTCTTTCTTCTGG	XDH	ENSG00000158125	0.21003099364606692	[981]	[1211,1332,1119,1129]	3	hSpCas9	negative selection	6372333
31388279	31388302	2	-	27260156	EWS502	viability	CTCTAGGATGGTGGATGCTGTGG	XDH	ENSG00000158125	-0.022324343685420356	[384]	[406,351,453,392]	0	hSpCas9	negative selection	6372334
31386518	31386541	2	+	27260156	EW8	viability	TCAAATCGCAGCTGCTTCCGAGG	XDH	ENSG00000158125	0.1552585013911778	[331]	[288,250,257,404]	3	hSpCas9	negative selection	6429336
31386421	31386444	2	+	27260156	EW8	viability	CGTGTTCCCCACGACCAGCTTGG	XDH	ENSG00000158125	0.44288671155917525	[1103]	[1324,1669,807,1141]	7	hSpCas9	negative selection	6429337
31387848	31387871	2	+	27260156	EW8	viability	TCCAGGGGCGTGAACTCCTCTGG	XDH	ENSG00000158125	0.19120675802333495	[497]	[484,527,478,349]	3	hSpCas9	negative selection	6429338
31387800	31387823	2	+	27260156	EW8	viability	GCATCACCTACCAGCAACTCTGG	XDH	ENSG00000158125	0.12554032471220755	[1112]	[831,946,951,1189]	2	hSpCas9	negative selection	6493583
31388223	31388246	2	+	27260156	EW8	viability	TTACTGAGTGGTCTTTCTTCTGG	XDH	ENSG00000158125	0.05169700798322818	[981]	[1006,900,657,779]	0	hSpCas9	negative selection	6493584
31388279	31388302	2	-	27260156	EW8	viability	CTCTAGGATGGTGGATGCTGTGG	XDH	ENSG00000158125	-0.27537031683685026	[384]	[196,275,357,175]	-5	hSpCas9	negative selection	6493585
31386518	31386541	2	+	27260156	CORL105	viability	TCAAATCGCAGCTGCTTCCGAGG	XDH	ENSG00000158125	0.7304214274205163	[331]	[778,606,582,605]	9	hSpCas9	negative selection	6550587
31386421	31386444	2	+	27260156	CORL105	viability	CGTGTTCCCCACGACCAGCTTGG	XDH	ENSG00000158125	0.4873698530559236	[1103]	[1919,1699,1982,1676]	8	hSpCas9	negative selection	6550588
31387848	31387871	2	+	27260156	CORL105	viability	TCCAGGGGCGTGAACTCCTCTGG	XDH	ENSG00000158125	0.14097065705145204	[497]	[746,552,776,520]	2	hSpCas9	negative selection	6550589
31387800	31387823	2	+	27260156	CORL105	viability	GCATCACCTACCAGCAACTCTGG	XDH	ENSG00000158125	-0.11414350451586319	[1112]	[914,1307,1245,1339]	-2	hSpCas9	negative selection	6614834
31388223	31388246	2	+	27260156	CORL105	viability	TTACTGAGTGGTCTTTCTTCTGG	XDH	ENSG00000158125	0.15674752066967357	[981]	[1359,1231,1271,1263]	3	hSpCas9	negative selection	6614835
31388279	31388302	2	-	27260156	CORL105	viability	CTCTAGGATGGTGGATGCTGTGG	XDH	ENSG00000158125	-0.2225153233007508	[384]	[358,337,312,522]	-4	hSpCas9	negative selection	6614836
31386518	31386541	2	+	27260156	HS294T	viability	TCAAATCGCAGCTGCTTCCGAGG	XDH	ENSG00000158125	0.9583674018742854	[331]	[377,242,166,185]	9	hSpCas9	negative selection	6671838
31386421	31386444	2	+	27260156	HS294T	viability	CGTGTTCCCCACGACCAGCTTGG	XDH	ENSG00000158125	0.8569600217103814	[1103]	[753,694,639,1051]	9	hSpCas9	negative selection	6671839
31387848	31387871	2	+	27260156	HS294T	viability	TCCAGGGGCGTGAACTCCTCTGG	XDH	ENSG00000158125	0.2027123293960281	[497]	[115,318,188,277]	2	hSpCas9	negative selection	6671840
31387800	31387823	2	+	27260156	HS294T	viability	GCATCACCTACCAGCAACTCTGG	XDH	ENSG00000158125	-0.2498121293357929	[1112]	[354,317,356,429]	-3	hSpCas9	negative selection	6736085
31388223	31388246	2	+	27260156	HS294T	viability	TTACTGAGTGGTCTTTCTTCTGG	XDH	ENSG00000158125	0.1772958116138963	[981]	[369,510,352,495]	2	hSpCas9	negative selection	6736086
31388279	31388302	2	-	27260156	HS294T	viability	CTCTAGGATGGTGGATGCTGTGG	XDH	ENSG00000158125	0.42886163344861905	[384]	[160,272,108,270]	6	hSpCas9	negative selection	6736087
31386518	31386541	2	+	27260156	HCC44	viability	TCAAATCGCAGCTGCTTCCGAGG	XDH	ENSG00000158125	0.28512917016673617	[331]	[680,238,614,372]	4	hSpCas9	negative selection	6793089
31386421	31386444	2	+	27260156	HCC44	viability	CGTGTTCCCCACGACCAGCTTGG	XDH	ENSG00000158125	0.4740680462917837	[1103]	[1536,1508,2403,1606]	7	hSpCas9	negative selection	6793090
31387848	31387871	2	+	27260156	HCC44	viability	TCCAGGGGCGTGAACTCCTCTGG	XDH	ENSG00000158125	0.11126718450189513	[497]	[575,657,700,502]	1	hSpCas9	negative selection	6793091
31387800	31387823	2	+	27260156	HCC44	viability	GCATCACCTACCAGCAACTCTGG	XDH	ENSG00000158125	0.2772800445436636	[1112]	[1913,1256,1804,1244]	4	hSpCas9	negative selection	6857336
31388223	31388246	2	+	27260156	HCC44	viability	TTACTGAGTGGTCTTTCTTCTGG	XDH	ENSG00000158125	0.2933202568407376	[981]	[1664,1146,1663,1076]	5	hSpCas9	negative selection	6857337
31388279	31388302	2	-	27260156	HCC44	viability	CTCTAGGATGGTGGATGCTGTGG	XDH	ENSG00000158125	-0.09554757525192797	[384]	[353,439,472,362]	-1	hSpCas9	negative selection	6857338
31386518	31386541	2	+	27260156	G402	viability	TCAAATCGCAGCTGCTTCCGAGG	XDH	ENSG00000158125	-0.22973741319234275	[331]	[282,499,304,294]	-3	hSpCas9	negative selection	6914340
31386421	31386444	2	+	27260156	G402	viability	CGTGTTCCCCACGACCAGCTTGG	XDH	ENSG00000158125	0.6890603851934538	[1103]	[2076,3369,1351,1946]	8	hSpCas9	negative selection	6914341
31387848	31387871	2	+	27260156	G402	viability	TCCAGGGGCGTGAACTCCTCTGG	XDH	ENSG00000158125	0.07608291240816006	[497]	[764,784,540,501]	0	hSpCas9	negative selection	6914342
31387800	31387823	2	+	27260156	G402	viability	GCATCACCTACCAGCAACTCTGG	XDH	ENSG00000158125	-0.21721350886565594	[1112]	[1414,1433,986,896]	-3	hSpCas9	negative selection	6978587
31388223	31388246	2	+	27260156	G402	viability	TTACTGAGTGGTCTTTCTTCTGG	XDH	ENSG00000158125	0.379393835052545	[981]	[1717,1593,1453,1490]	5	hSpCas9	negative selection	6978588
31388279	31388302	2	-	27260156	G402	viability	CTCTAGGATGGTGGATGCTGTGG	XDH	ENSG00000158125	-0.15584149024821636	[384]	[351,360,229,713]	-2	hSpCas9	negative selection	6978589
31386518	31386541	2	+	27260156	L33	viability	TCAAATCGCAGCTGCTTCCGAGG	XDH	ENSG00000158125	0.5421233830275667	[331]	[429,206,366,416]	9	hSpCas9	negative selection	7035591
31386421	31386444	2	+	27260156	L33	viability	CGTGTTCCCCACGACCAGCTTGG	XDH	ENSG00000158125	0.39447155780817833	[1103]	[1448,660,916,1284]	7	hSpCas9	negative selection	7035592
31387848	31387871	2	+	27260156	L33	viability	TCCAGGGGCGTGAACTCCTCTGG	XDH	ENSG00000158125	0.00509398429699201	[497]	[594,165,334,463]	0	hSpCas9	negative selection	7035593
31387800	31387823	2	+	27260156	L33	viability	GCATCACCTACCAGCAACTCTGG	XDH	ENSG00000158125	-0.056871571570296764	[1112]	[1097,428,678,1053]	-1	hSpCas9	negative selection	7099838
31388223	31388246	2	+	27260156	L33	viability	TTACTGAGTGGTCTTTCTTCTGG	XDH	ENSG00000158125	0.1387562320303981	[981]	[1000,434,700,1147]	3	hSpCas9	negative selection	7099839
31388279	31388302	2	-	27260156	L33	viability	CTCTAGGATGGTGGATGCTGTGG	XDH	ENSG00000158125	-0.22551608403100526	[384]	[448,122,184,270]	-5	hSpCas9	negative selection	7099840
31386518	31386541	2	+	27260156	K562	viability	TCAAATCGCAGCTGCTTCCGAGG	XDH	ENSG00000158125	-0.6694840598014699	[331]	[123,151,239,213]	-7	hSpCas9	negative selection	7156842
31386421	31386444	2	+	27260156	K562	viability	CGTGTTCCCCACGACCAGCTTGG	XDH	ENSG00000158125	0.858683089728352	[1103]	[2317,1419,1454,1914]	9	hSpCas9	negative selection	7156843
31387848	31387871	2	+	27260156	K562	viability	TCCAGGGGCGTGAACTCCTCTGG	XDH	ENSG00000158125	0.24991008571506554	[497]	[424,640,461,564]	3	hSpCas9	negative selection	7156844
31387800	31387823	2	+	27260156	K562	viability	GCATCACCTACCAGCAACTCTGG	XDH	ENSG00000158125	0.26722752498729063	[1112]	[1069,1502,1357,863]	3	hSpCas9	negative selection	7221089
31388223	31388246	2	+	27260156	K562	viability	TTACTGAGTGGTCTTTCTTCTGG	XDH	ENSG00000158125	0.5357741445601467	[981]	[805,1398,1400,1395]	6	hSpCas9	negative selection	7221090
31388279	31388302	2	-	27260156	K562	viability	CTCTAGGATGGTGGATGCTGTGG	XDH	ENSG00000158125	-0.512104786001631	[384]	[195,184,246,313]	-6	hSpCas9	negative selection	7221091
31386518	31386541	2	+	27260156	HT29	viability	TCAAATCGCAGCTGCTTCCGAGG	XDH	ENSG00000158125	0.19389119958629897	[331]	[527,459,495,374]	4	hSpCas9	negative selection	7278093
31386421	31386444	2	+	27260156	HT29	viability	CGTGTTCCCCACGACCAGCTTGG	XDH	ENSG00000158125	0.44811136504172366	[1103]	[1842,2015,1834,1654]	8	hSpCas9	negative selection	7278094
31387848	31387871	2	+	27260156	HT29	viability	TCCAGGGGCGTGAACTCCTCTGG	XDH	ENSG00000158125	-0.07480770648521519	[497]	[693,606,539,477]	-1	hSpCas9	negative selection	7278095
31387800	31387823	2	+	27260156	HT29	viability	GCATCACCTACCAGCAACTCTGG	XDH	ENSG00000158125	0.09053718519361231	[1112]	[1636,1477,1499,1186]	1	hSpCas9	negative selection	7342340
31388223	31388246	2	+	27260156	HT29	viability	TTACTGAGTGGTCTTTCTTCTGG	XDH	ENSG00000158125	0.057046627854570486	[981]	[1526,1518,1091,907]	1	hSpCas9	negative selection	7342341
31388279	31388302	2	-	27260156	HT29	viability	CTCTAGGATGGTGGATGCTGTGG	XDH	ENSG00000158125	-0.2982284009789233	[384]	[497,368,273,385]	-5	hSpCas9	negative selection	7342342
31386518	31386541	2	+	27260156	MHHES1	viability	TCAAATCGCAGCTGCTTCCGAGG	XDH	ENSG00000158125	0.43638059709049265	[331]	[710,639,330,393]	7	hSpCas9	negative selection	7399344
31386421	31386444	2	+	27260156	MHHES1	viability	CGTGTTCCCCACGACCAGCTTGG	XDH	ENSG00000158125	0.49730689598876987	[1103]	[1992,2102,1649,1384]	8	hSpCas9	negative selection	7399345
31387848	31387871	2	+	27260156	MHHES1	viability	TCCAGGGGCGTGAACTCCTCTGG	XDH	ENSG00000158125	-0.129175731343474	[497]	[557,559,483,459]	-2	hSpCas9	negative selection	7399346
31387800	31387823	2	+	27260156	MHHES1	viability	GCATCACCTACCAGCAACTCTGG	XDH	ENSG00000158125	0.060400815151199216	[1112]	[1467,1222,1284,1246]	1	hSpCas9	negative selection	7463591
31388223	31388246	2	+	27260156	MHHES1	viability	TTACTGAGTGGTCTTTCTTCTGG	XDH	ENSG00000158125	0.6205885883303548	[981]	[1399,1705,2584,1167]	9	hSpCas9	negative selection	7463592
31388279	31388302	2	-	27260156	MHHES1	viability	CTCTAGGATGGTGGATGCTGTGG	XDH	ENSG00000158125	-0.39398679268467923	[384]	[398,221,379,312]	-6	hSpCas9	negative selection	7463593
31386518	31386541	2	+	27260156	MEWO	viability	TCAAATCGCAGCTGCTTCCGAGG	XDH	ENSG00000158125	0.34751113352551394	[331]	[425,495,268]	7	hSpCas9	negative selection	7520595
31386421	31386444	2	+	27260156	MEWO	viability	CGTGTTCCCCACGACCAGCTTGG	XDH	ENSG00000158125	0.5127161668463822	[1103]	[1645,1456,1350]	9	hSpCas9	negative selection	7520596
31387848	31387871	2	+	27260156	MEWO	viability	TCCAGGGGCGTGAACTCCTCTGG	XDH	ENSG00000158125	0.24307894152671536	[497]	[684,549,444]	5	hSpCas9	negative selection	7520597
31387800	31387823	2	+	27260156	MEWO	viability	GCATCACCTACCAGCAACTCTGG	XDH	ENSG00000158125	0.2619487090913415	[1112]	[1253,1157,1334]	5	hSpCas9	negative selection	7584842
31388223	31388246	2	+	27260156	MEWO	viability	TTACTGAGTGGTCTTTCTTCTGG	XDH	ENSG00000158125	-0.13451001858165446	[981]	[921,857,746]	-3	hSpCas9	negative selection	7584843
31388279	31388302	2	-	27260156	MEWO	viability	CTCTAGGATGGTGGATGCTGTGG	XDH	ENSG00000158125	0.031088491013919084	[384]	[387,346,372]	0	hSpCas9	negative selection	7584844
31386518	31386541	2	+	27260156	LNCAPCLONEFGC	viability	TCAAATCGCAGCTGCTTCCGAGG	XDH	ENSG00000158125	0.1583062397477849	[331]	[407,312,339,281]	2	hSpCas9	negative selection	7641846
31386421	31386444	2	+	27260156	LNCAPCLONEFGC	viability	CGTGTTCCCCACGACCAGCTTGG	XDH	ENSG00000158125	0.5553973225757578	[1103]	[1485,1242,1864,1356]	8	hSpCas9	negative selection	7641847
31387848	31387871	2	+	27260156	LNCAPCLONEFGC	viability	TCCAGGGGCGTGAACTCCTCTGG	XDH	ENSG00000158125	0.20978462070857715	[497]	[443,499,659,505]	3	hSpCas9	negative selection	7641848
31387800	31387823	2	+	27260156	LNCAPCLONEFGC	viability	GCATCACCTACCAGCAACTCTGG	XDH	ENSG00000158125	0.2845810884752922	[1112]	[1020,1191,1336,1383]	4	hSpCas9	negative selection	7706093
31388223	31388246	2	+	27260156	LNCAPCLONEFGC	viability	TTACTGAGTGGTCTTTCTTCTGG	XDH	ENSG00000158125	0.4230636156862879	[981]	[1193,1140,1412,1057]	6	hSpCas9	negative selection	7706094
31388279	31388302	2	-	27260156	LNCAPCLONEFGC	viability	CTCTAGGATGGTGGATGCTGTGG	XDH	ENSG00000158125	-0.20046643091182448	[384]	[265,257,393,312]	-3	hSpCas9	negative selection	7706095
31386518	31386541	2	+	27260156	PANC0327	viability	TCAAATCGCAGCTGCTTCCGAGG	XDH	ENSG00000158125	0.6414421503318276	[331]	[575,279,584,431]	8	hSpCas9	negative selection	7763097
31386421	31386444	2	+	27260156	PANC0327	viability	CGTGTTCCCCACGACCAGCTTGG	XDH	ENSG00000158125	0.6260461924698781	[1103]	[2439,1296,1093,1325]	8	hSpCas9	negative selection	7763098
31387848	31387871	2	+	27260156	PANC0327	viability	TCCAGGGGCGTGAACTCCTCTGG	XDH	ENSG00000158125	0.3340070645817299	[497]	[801,355,396,720]	5	hSpCas9	negative selection	7763099
31387800	31387823	2	+	27260156	PANC0327	viability	GCATCACCTACCAGCAACTCTGG	XDH	ENSG00000158125	0.12397818312922504	[1112]	[1668,683,795,1258]	1	hSpCas9	negative selection	7827344
31388223	31388246	2	+	27260156	PANC0327	viability	TTACTGAGTGGTCTTTCTTCTGG	XDH	ENSG00000158125	0.3879825260470098	[981]	[1152,886,1479,1079]	6	hSpCas9	negative selection	7827345
31388279	31388302	2	-	27260156	PANC0327	viability	CTCTAGGATGGTGGATGCTGTGG	XDH	ENSG00000158125	0.23110868594939477	[384]	[451,382,364,411]	3	hSpCas9	negative selection	7827346
31386518	31386541	2	+	27260156	NCIH2009	viability	TCAAATCGCAGCTGCTTCCGAGG	XDH	ENSG00000158125	0.33651318841378697	[331]	[774,450,569]	4	hSpCas9	negative selection	7884348
31386421	31386444	2	+	27260156	NCIH2009	viability	CGTGTTCCCCACGACCAGCTTGG	XDH	ENSG00000158125	0.6732775893812553	[1103]	[2622,2147,2641]	8	hSpCas9	negative selection	7884349
31387848	31387871	2	+	27260156	NCIH2009	viability	TCCAGGGGCGTGAACTCCTCTGG	XDH	ENSG00000158125	-0.03271480668215097	[497]	[951,686,453]	0	hSpCas9	negative selection	7884350
31387800	31387823	2	+	27260156	NCIH2009	viability	GCATCACCTACCAGCAACTCTGG	XDH	ENSG00000158125	-0.16473181472607323	[1112]	[1752,1202,1278]	-2	hSpCas9	negative selection	7948595
31388223	31388246	2	+	27260156	NCIH2009	viability	TTACTGAGTGGTCTTTCTTCTGG	XDH	ENSG00000158125	0.4180356972866177	[981]	[1770,1835,1876]	6	hSpCas9	negative selection	7948596
31388279	31388302	2	-	27260156	NCIH2009	viability	CTCTAGGATGGTGGATGCTGTGG	XDH	ENSG00000158125	-0.3905751562350474	[384]	[442,230,565]	-5	hSpCas9	negative selection	7948597
31386518	31386541	2	+	27260156	NCIH1373	viability	TCAAATCGCAGCTGCTTCCGAGG	XDH	ENSG00000158125	-0.12784378369346894	[331]	[448,345,349,58]	-1	hSpCas9	negative selection	8005599
31386421	31386444	2	+	27260156	NCIH1373	viability	CGTGTTCCCCACGACCAGCTTGG	XDH	ENSG00000158125	0.7314600893223613	[1103]	[2056,2021,2254,488]	7	hSpCas9	negative selection	8005600
31387848	31387871	2	+	27260156	NCIH1373	viability	TCCAGGGGCGTGAACTCCTCTGG	XDH	ENSG00000158125	-0.036518219580817315	[497]	[530,718,484,107]	0	hSpCas9	negative selection	8005601
31387800	31387823	2	+	27260156	NCIH1373	viability	GCATCACCTACCAGCAACTCTGG	XDH	ENSG00000158125	-0.18234176510692768	[1112]	[850,795,1102,438]	-2	hSpCas9	negative selection	8069846
31388223	31388246	2	+	27260156	NCIH1373	viability	TTACTGAGTGGTCTTTCTTCTGG	XDH	ENSG00000158125	0.7066943529602996	[981]	[1571,1764,1799,530]	7	hSpCas9	negative selection	8069847
31388279	31388302	2	-	27260156	NCIH1373	viability	CTCTAGGATGGTGGATGCTGTGG	XDH	ENSG00000158125	-1.1961589829886923	[384]	[184,218,119,59]	-8	hSpCas9	negative selection	8069848
31386518	31386541	2	+	27260156	PATU8902	viability	TCAAATCGCAGCTGCTTCCGAGG	XDH	ENSG00000158125	0.8721401872361798	[331]	[1040,1385,360,697]	8	hSpCas9	negative selection	8126850
31386421	31386444	2	+	27260156	PATU8902	viability	CGTGTTCCCCACGACCAGCTTGG	XDH	ENSG00000158125	0.5942034800602158	[1103]	[2834,1731,2208,2535]	6	hSpCas9	negative selection	8126851
31387848	31387871	2	+	27260156	PATU8902	viability	TCCAGGGGCGTGAACTCCTCTGG	XDH	ENSG00000158125	0.1090507249176749	[497]	[614,963,649,789]	1	hSpCas9	negative selection	8126852
31387800	31387823	2	+	27260156	PATU8902	viability	GCATCACCTACCAGCAACTCTGG	XDH	ENSG00000158125	-0.16349333302951252	[1112]	[1260,1491,800,2224]	-2	hSpCas9	negative selection	8191097
31388223	31388246	2	+	27260156	PATU8902	viability	TTACTGAGTGGTCTTTCTTCTGG	XDH	ENSG00000158125	0.47448023991854416	[981]	[1793,1270,1836,2807]	5	hSpCas9	negative selection	8191098
31388279	31388302	2	-	27260156	PATU8902	viability	CTCTAGGATGGTGGATGCTGTGG	XDH	ENSG00000158125	-0.08451294075973192	[384]	[399,312,499,848]	-1	hSpCas9	negative selection	8191099
31386518	31386541	2	+	27260156	PANC1	viability	TCAAATCGCAGCTGCTTCCGAGG	XDH	ENSG00000158125	-0.06637830503575648	[331]	[345,289,210,243]	-1	hSpCas9	negative selection	8248101
31386421	31386444	2	+	27260156	PANC1	viability	CGTGTTCCCCACGACCAGCTTGG	XDH	ENSG00000158125	0.3456021142521033	[1103]	[1120,1618,1077,1086]	5	hSpCas9	negative selection	8248102
31387848	31387871	2	+	27260156	PANC1	viability	TCCAGGGGCGTGAACTCCTCTGG	XDH	ENSG00000158125	0.19279768762634522	[497]	[441,832,430,337]	3	hSpCas9	negative selection	8248103
31387800	31387823	2	+	27260156	PANC1	viability	GCATCACCTACCAGCAACTCTGG	XDH	ENSG00000158125	0.15878752466497215	[1112]	[1411,1165,900,823]	2	hSpCas9	negative selection	8312348
31388223	31388246	2	+	27260156	PANC1	viability	TTACTGAGTGGTCTTTCTTCTGG	XDH	ENSG00000158125	0.21908300581910645	[981]	[1049,1163,923,832]	3	hSpCas9	negative selection	8312349
31388279	31388302	2	-	27260156	PANC1	viability	CTCTAGGATGGTGGATGCTGTGG	XDH	ENSG00000158125	-0.14138785603439424	[384]	[234,384,391,215]	-2	hSpCas9	negative selection	8312350
31386518	31386541	2	+	27260156	PANC0813	viability	TCAAATCGCAGCTGCTTCCGAGG	XDH	ENSG00000158125	0.5199473961465334	[331]	[600,477,567,590]	8	hSpCas9	negative selection	8369352
31386421	31386444	2	+	27260156	PANC0813	viability	CGTGTTCCCCACGACCAGCTTGG	XDH	ENSG00000158125	0.7714580665623365	[1103]	[2467,2490,2132,1804]	9	hSpCas9	negative selection	8369353
31387848	31387871	2	+	27260156	PANC0813	viability	TCCAGGGGCGTGAACTCCTCTGG	XDH	ENSG00000158125	0.21346087992201204	[497]	[683,632,654,736]	3	hSpCas9	negative selection	8369354
31387800	31387823	2	+	27260156	PANC0813	viability	GCATCACCTACCAGCAACTCTGG	XDH	ENSG00000158125	0.0373743854643005	[1112]	[1560,1298,1112,1406]	0	hSpCas9	negative selection	8433599
31388223	31388246	2	+	27260156	PANC0813	viability	TTACTGAGTGGTCTTTCTTCTGG	XDH	ENSG00000158125	0.4711803306529101	[981]	[1452,1859,1721,1358]	7	hSpCas9	negative selection	8433600
31388279	31388302	2	-	27260156	PANC0813	viability	CTCTAGGATGGTGGATGCTGTGG	XDH	ENSG00000158125	-0.2843646738407664	[384]	[339,360,460,322]	-4	hSpCas9	negative selection	8433601
31386518	31386541	2	+	27260156	RDES	viability	TCAAATCGCAGCTGCTTCCGAGG	XDH	ENSG00000158125	-0.001836801778795083	[331]	[501,266,280,451]	0	hSpCas9	negative selection	8490603
31386421	31386444	2	+	27260156	RDES	viability	CGTGTTCCCCACGACCAGCTTGG	XDH	ENSG00000158125	0.34856479680610253	[1103]	[1260,1557,1769,1971]	5	hSpCas9	negative selection	8490604
31387848	31387871	2	+	27260156	RDES	viability	TCCAGGGGCGTGAACTCCTCTGG	XDH	ENSG00000158125	0.16608802930482688	[497]	[463,597,605,976]	2	hSpCas9	negative selection	8490605
31387800	31387823	2	+	27260156	RDES	viability	GCATCACCTACCAGCAACTCTGG	XDH	ENSG00000158125	0.09803120829937595	[1112]	[1057,1428,1228,1852]	1	hSpCas9	negative selection	8554850
31388223	31388246	2	+	27260156	RDES	viability	TTACTGAGTGGTCTTTCTTCTGG	XDH	ENSG00000158125	0.2898399958784228	[981]	[1225,1215,1561,1557]	4	hSpCas9	negative selection	8554851
31388279	31388302	2	-	27260156	RDES	viability	CTCTAGGATGGTGGATGCTGTGG	XDH	ENSG00000158125	-0.35588382597430485	[384]	[229,386,424,357]	-6	hSpCas9	negative selection	8554852
31386518	31386541	2	+	27260156	PC3	viability	TCAAATCGCAGCTGCTTCCGAGG	XDH	ENSG00000158125	0.48013441074206287	[331]	[325,483,939,282]	8	hSpCas9	negative selection	8611854
31386421	31386444	2	+	27260156	PC3	viability	CGTGTTCCCCACGACCAGCTTGG	XDH	ENSG00000158125	0.4808616383923243	[1103]	[1080,1302,2529,1669]	8	hSpCas9	negative selection	8611855
31387848	31387871	2	+	27260156	PC3	viability	TCCAGGGGCGTGAACTCCTCTGG	XDH	ENSG00000158125	0.4815567536334443	[497]	[426,626,1362,669]	8	hSpCas9	negative selection	8611856
31387800	31387823	2	+	27260156	PC3	viability	GCATCACCTACCAGCAACTCTGG	XDH	ENSG00000158125	0.1586593993854839	[1112]	[829,1264,1784,1338]	3	hSpCas9	negative selection	8676101
31388223	31388246	2	+	27260156	PC3	viability	TTACTGAGTGGTCTTTCTTCTGG	XDH	ENSG00000158125	0.15119148508052893	[981]	[787,1116,1812,912]	3	hSpCas9	negative selection	8676102
31388279	31388302	2	-	27260156	PC3	viability	CTCTAGGATGGTGGATGCTGTGG	XDH	ENSG00000158125	-0.21355984609246154	[384]	[195,319,686,286]	-5	hSpCas9	negative selection	8676103
31386518	31386541	2	+	27260156	PATU8988T	viability	TCAAATCGCAGCTGCTTCCGAGG	XDH	ENSG00000158125	0.16418048581391476	[331]	[261,411,467,293]	3	hSpCas9	negative selection	8733105
31386421	31386444	2	+	27260156	PATU8988T	viability	CGTGTTCCCCACGACCAGCTTGG	XDH	ENSG00000158125	0.3930018018800068	[1103]	[1552,1521,1503,1001]	6	hSpCas9	negative selection	8733106
31387848	31387871	2	+	27260156	PATU8988T	viability	TCCAGGGGCGTGAACTCCTCTGG	XDH	ENSG00000158125	0.379499240310027	[497]	[840,396,604,640]	6	hSpCas9	negative selection	8733107
31387800	31387823	2	+	27260156	PATU8988T	viability	GCATCACCTACCAGCAACTCTGG	XDH	ENSG00000158125	0.11850672592854927	[1112]	[735,1296,1504,1136]	2	hSpCas9	negative selection	8797352
31388223	31388246	2	+	27260156	PATU8988T	viability	TTACTGAGTGGTCTTTCTTCTGG	XDH	ENSG00000158125	0.06698324126480282	[981]	[805,1274,859,1068]	1	hSpCas9	negative selection	8797353
31388279	31388302	2	-	27260156	PATU8988T	viability	CTCTAGGATGGTGGATGCTGTGG	XDH	ENSG00000158125	-0.3395065147270013	[384]	[266,325,262,325]	-5	hSpCas9	negative selection	8797354
31386518	31386541	2	+	27260156	T47D	viability	TCAAATCGCAGCTGCTTCCGAGG	XDH	ENSG00000158125	0.2776637594543711	[331]	[457,465,426,526]	6	hSpCas9	negative selection	8854356
31386421	31386444	2	+	27260156	T47D	viability	CGTGTTCCCCACGACCAGCTTGG	XDH	ENSG00000158125	0.3706485156347876	[1103]	[1660,1621,1684,1686]	7	hSpCas9	negative selection	8854357
31387848	31387871	2	+	27260156	T47D	viability	TCCAGGGGCGTGAACTCCTCTGG	XDH	ENSG00000158125	0.12868748686431858	[497]	[679,541,633,690]	2	hSpCas9	negative selection	8854358
31387800	31387823	2	+	27260156	T47D	viability	GCATCACCTACCAGCAACTCTGG	XDH	ENSG00000158125	0.022333074389326857	[1112]	[1410,1205,1253,1409]	0	hSpCas9	negative selection	8918603
31388223	31388246	2	+	27260156	T47D	viability	TTACTGAGTGGTCTTTCTTCTGG	XDH	ENSG00000158125	0.19155442073300155	[981]	[1212,1229,1274,1520]	4	hSpCas9	negative selection	8918604
31388279	31388302	2	-	27260156	T47D	viability	CTCTAGGATGGTGGATGCTGTGG	XDH	ENSG00000158125	-0.011111431575172859	[384]	[415,397,399,574]	0	hSpCas9	negative selection	8918605
31386518	31386541	2	+	27260156	SU8686	viability	TCAAATCGCAGCTGCTTCCGAGG	XDH	ENSG00000158125	0.4729386040605262	[331]	[304,433,571,551]	7	hSpCas9	negative selection	8975607
31386421	31386444	2	+	27260156	SU8686	viability	CGTGTTCCCCACGACCAGCTTGG	XDH	ENSG00000158125	0.5296290672147319	[1103]	[1471,1537,1488,1871]	8	hSpCas9	negative selection	8975608
31387848	31387871	2	+	27260156	SU8686	viability	TCCAGGGGCGTGAACTCCTCTGG	XDH	ENSG00000158125	0.3072140126733883	[497]	[522,476,741,750]	5	hSpCas9	negative selection	8975609
31387800	31387823	2	+	27260156	SU8686	viability	GCATCACCTACCAGCAACTCTGG	XDH	ENSG00000158125	0.19678968885456194	[1112]	[1347,1043,1402,1279]	3	hSpCas9	negative selection	9039854
31388223	31388246	2	+	27260156	SU8686	viability	TTACTGAGTGGTCTTTCTTCTGG	XDH	ENSG00000158125	0.4003927243984553	[981]	[930,1214,1608,1462]	6	hSpCas9	negative selection	9039855
31388279	31388302	2	-	27260156	SU8686	viability	CTCTAGGATGGTGGATGCTGTGG	XDH	ENSG00000158125	0.048173417889947445	[384]	[262,331,528,494]	0	hSpCas9	negative selection	9039856
31386518	31386541	2	+	27260156	SKES1	viability	TCAAATCGCAGCTGCTTCCGAGG	XDH	ENSG00000158125	0.04225337460449202	[331]	[406,328,407,235]	0	hSpCas9	negative selection	9096858
31386421	31386444	2	+	27260156	SKES1	viability	CGTGTTCCCCACGACCAGCTTGG	XDH	ENSG00000158125	0.29749045019834774	[1103]	[1609,1433,1354,1078]	6	hSpCas9	negative selection	9096859
31387848	31387871	2	+	27260156	SKES1	viability	TCCAGGGGCGTGAACTCCTCTGG	XDH	ENSG00000158125	0.2147655013117404	[497]	[593,689,606,440]	4	hSpCas9	negative selection	9096860
31387800	31387823	2	+	27260156	SKES1	viability	GCATCACCTACCAGCAACTCTGG	XDH	ENSG00000158125	-0.020352802579916007	[1112]	[1031,1181,1035,1116]	0	hSpCas9	negative selection	9161105
31388223	31388246	2	+	27260156	SKES1	viability	TTACTGAGTGGTCTTTCTTCTGG	XDH	ENSG00000158125	0.11571832971890594	[981]	[1115,1182,974,991]	2	hSpCas9	negative selection	9161106
31388279	31388302	2	-	27260156	SKES1	viability	CTCTAGGATGGTGGATGCTGTGG	XDH	ENSG00000158125	-0.2679007486010853	[384]	[366,273,284,344]	-5	hSpCas9	negative selection	9161107
31386518	31386541	2	+	27260156	TOV112D	viability	TCAAATCGCAGCTGCTTCCGAGG	XDH	ENSG00000158125	0.259323759918587	[331]	[341,594,405,294]	5	hSpCas9	negative selection	9218109
31386421	31386444	2	+	27260156	TOV112D	viability	CGTGTTCCCCACGACCAGCTTGG	XDH	ENSG00000158125	0.32254353180361983	[1103]	[1145,1702,1409,1329]	6	hSpCas9	negative selection	9218110
31387848	31387871	2	+	27260156	TOV112D	viability	TCCAGGGGCGTGAACTCCTCTGG	XDH	ENSG00000158125	0.22548639073932694	[497]	[439,978,559,441]	4	hSpCas9	negative selection	9218111
31387800	31387823	2	+	27260156	TOV112D	viability	GCATCACCTACCAGCAACTCTGG	XDH	ENSG00000158125	-0.0378296528513522	[1112]	[1453,1143,847,944]	0	hSpCas9	negative selection	9282356
31388223	31388246	2	+	27260156	TOV112D	viability	TTACTGAGTGGTCTTTCTTCTGG	XDH	ENSG00000158125	0.3638133311741878	[981]	[1200,1866,1052,1086]	7	hSpCas9	negative selection	9282357
31388279	31388302	2	-	27260156	TOV112D	viability	CTCTAGGATGGTGGATGCTGTGG	XDH	ENSG00000158125	-0.33023372742362717	[384]	[301,459,243,258]	-6	hSpCas9	negative selection	9282358
31386518	31386541	2	+	27260156	TC71	viability	TCAAATCGCAGCTGCTTCCGAGG	XDH	ENSG00000158125	0.4443544607286912	[331]	[495,449,465,527]	8	hSpCas9	negative selection	9339360
31386421	31386444	2	+	27260156	TC71	viability	CGTGTTCCCCACGACCAGCTTGG	XDH	ENSG00000158125	0.27931860066153447	[1103]	[1405,1311,1342,1703]	6	hSpCas9	negative selection	9339361
31387848	31387871	2	+	27260156	TC71	viability	TCCAGGGGCGTGAACTCCTCTGG	XDH	ENSG00000158125	0.165416912284621	[497]	[532,622,617,622]	4	hSpCas9	negative selection	9339362
31387800	31387823	2	+	27260156	TC71	viability	GCATCACCTACCAGCAACTCTGG	XDH	ENSG00000158125	0.06235164145634431	[1112]	[1198,1302,1139,1351]	1	hSpCas9	negative selection	9403607
31388223	31388246	2	+	27260156	TC71	viability	TTACTGAGTGGTCTTTCTTCTGG	XDH	ENSG00000158125	0.22986662307750105	[981]	[1084,1273,1169,1425]	5	hSpCas9	negative selection	9403608
31388279	31388302	2	-	27260156	TC71	viability	CTCTAGGATGGTGGATGCTGTGG	XDH	ENSG00000158125	-0.05222422946025873	[384]	[443,389,362,394]	-1	hSpCas9	negative selection	9403609
31386518	31386541	2	+	27260156	TC32	viability	TCAAATCGCAGCTGCTTCCGAGG	XDH	ENSG00000158125	-0.028972463476456878	[331]	[297,217,346,387]	0	hSpCas9	negative selection	9460611
31386421	31386444	2	+	27260156	TC32	viability	CGTGTTCCCCACGACCAGCTTGG	XDH	ENSG00000158125	0.4210993015156206	[1103]	[1448,864,1806,1631]	7	hSpCas9	negative selection	9460612
31387848	31387871	2	+	27260156	TC32	viability	TCCAGGGGCGTGAACTCCTCTGG	XDH	ENSG00000158125	0.21224572016833085	[497]	[660,398,493,614]	4	hSpCas9	negative selection	9460613
31387800	31387823	2	+	27260156	TC32	viability	GCATCACCTACCAGCAACTCTGG	XDH	ENSG00000158125	0.06342034770058125	[1112]	[957,668,1548,1409]	1	hSpCas9	negative selection	9524858
31388223	31388246	2	+	27260156	TC32	viability	TTACTGAGTGGTCTTTCTTCTGG	XDH	ENSG00000158125	0.11643356256245285	[981]	[975,736,1352,1041]	2	hSpCas9	negative selection	9524859
31388279	31388302	2	-	27260156	TC32	viability	CTCTAGGATGGTGGATGCTGTGG	XDH	ENSG00000158125	-0.22698984725248533	[384]	[418,242,318,243]	-4	hSpCas9	negative selection	9524860
31377102	31377125	2	-	27869803	HPAFII	viability after 27 days	GGCCCTTTGCTATGGTGGAATGG	XDH	ENSG00000158125	0.30006504288616187	[207]	[114,150,NaN]	2	hSpCas9	negative selection	9574790
31383084	31383107	2	+	27869803	HPAFII	viability after 27 days	GCTTAGCAACAGCATCCACCAGG	XDH	ENSG00000158125	1.125034379630668	[193]	[336,126,NaN]	8	hSpCas9	negative selection	9574791
31383754	31383777	2	-	27869803	HPAFII	viability after 27 days	TCGGTAGAACATGGACCCGACGG	XDH	ENSG00000158125	0.46514008586606786	[239]	[57,270,NaN]	4	hSpCas9	negative selection	9574792
31397708	31397731	2	-	27869803	HPAFII	viability after 27 days	GGAAATCTGTGCCGCTGCACAGG	XDH	ENSG00000158125	1.2781778920943356	[153]	[119,259,NaN]	9	hSpCas9	negative selection	9574793
31398634	31398657	2	+	27869803	HPAFII	viability after 27 days	CATACTCATGACGATGCCAGGGG	XDH	ENSG00000158125	-1.06867714393848	[279]	[145,6,NaN]	-6	hSpCas9	negative selection	9574794
31403109	31403132	2	-	27869803	HPAFII	viability after 27 days	AACCAAGCTCGGCTGTGGAGAGG	XDH	ENSG00000158125	0.021747165550227376	[154]	[97,69,NaN]	0	hSpCas9	negative selection	9574795
31377102	31377125	2	-	27869803	HPAFII	viability after 15 days	GGCCCTTTGCTATGGTGGAATGG	XDH	ENSG00000158125	0.8173207836755433	[207]	[359,414,NaN]	8	hSpCas9	negative selection	9657239
31383084	31383107	2	+	27869803	HPAFII	viability after 15 days	GCTTAGCAACAGCATCCACCAGG	XDH	ENSG00000158125	0.6958003058361949	[193]	[555,201,NaN]	7	hSpCas9	negative selection	9657240
31383754	31383777	2	-	27869803	HPAFII	viability after 15 days	TCGGTAGAACATGGACCCGACGG	XDH	ENSG00000158125	0.13137751306989073	[239]	[210,326,NaN]	1	hSpCas9	negative selection	9657241
31397708	31397731	2	-	27869803	HPAFII	viability after 15 days	GGAAATCTGTGCCGCTGCACAGG	XDH	ENSG00000158125	0.9828692037056133	[153]	[426,264,NaN]	9	hSpCas9	negative selection	9657242
31398634	31398657	2	+	27869803	HPAFII	viability after 15 days	CATACTCATGACGATGCCAGGGG	XDH	ENSG00000158125	-1.421289822351935	[279]	[202,55,NaN]	-8	hSpCas9	negative selection	9657243
31403109	31403132	2	-	27869803	HPAFII	viability after 15 days	AACCAAGCTCGGCTGTGGAGAGG	XDH	ENSG00000158125	-0.4597826607462536	[154]	[175,86,NaN]	-5	hSpCas9	negative selection	9657244
31377102	31377125	2	-	27869803	ASPC1	viability after 36 days	GGCCCTTTGCTATGGTGGAATGG	XDH	ENSG00000158125	1.1893889331046317	[695]	[548,835,327]	9	hSpCas9	negative selection	9739688
31383084	31383107	2	+	27869803	ASPC1	viability after 36 days	GCTTAGCAACAGCATCCACCAGG	XDH	ENSG00000158125	0.4664078701263535	[456]	[83,427,148]	5	hSpCas9	negative selection	9739689
31383754	31383777	2	-	27869803	ASPC1	viability after 36 days	TCGGTAGAACATGGACCCGACGG	XDH	ENSG00000158125	-0.5698221106897138	[525]	[107,127,129]	-5	hSpCas9	negative selection	9739690
31397708	31397731	2	-	27869803	ASPC1	viability after 36 days	GGAAATCTGTGCCGCTGCACAGG	XDH	ENSG00000158125	1.7023648082599117	[267]	[329,290,293]	9	hSpCas9	negative selection	9739691
31398634	31398657	2	+	27869803	ASPC1	viability after 36 days	CATACTCATGACGATGCCAGGGG	XDH	ENSG00000158125	1.518519585449373	[467]	[363,835,243]	9	hSpCas9	negative selection	9739692
31403109	31403132	2	-	27869803	ASPC1	viability after 36 days	AACCAAGCTCGGCTGTGGAGAGG	XDH	ENSG00000158125	-0.15217347989864427	[523]	[100,265,126]	-1	hSpCas9	negative selection	9739693
31377102	31377125	2	-	27869803	PATU8988S	viability after 35 days	GGCCCTTTGCTATGGTGGAATGG	XDH	ENSG00000158125	0.17202122533897157	[713]	[314,332,NaN]	2	hSpCas9	negative selection	9822137
31383084	31383107	2	+	27869803	PATU8988S	viability after 35 days	GCTTAGCAACAGCATCCACCAGG	XDH	ENSG00000158125	0.43601830777691575	[345]	[198,177,NaN]	5	hSpCas9	negative selection	9822138
31383754	31383777	2	-	27869803	PATU8988S	viability after 35 days	TCGGTAGAACATGGACCCGACGG	XDH	ENSG00000158125	0.3884051625730418	[435]	[163,295,NaN]	4	hSpCas9	negative selection	9822139
31397708	31397731	2	-	27869803	PATU8988S	viability after 35 days	GGAAATCTGTGCCGCTGCACAGG	XDH	ENSG00000158125	-0.47684710806065456	[338]	[143,51,NaN]	-5	hSpCas9	negative selection	9822140
31398634	31398657	2	+	27869803	PATU8988S	viability after 35 days	CATACTCATGACGATGCCAGGGG	XDH	ENSG00000158125	-0.6068593359345622	[530]	[107,172,NaN]	-6	hSpCas9	negative selection	9822141
31403109	31403132	2	-	27869803	PATU8988S	viability after 35 days	AACCAAGCTCGGCTGTGGAGAGG	XDH	ENSG00000158125	0.32007621746879666	[338]	[146,193,NaN]	3	hSpCas9	negative selection	9822142
31377102	31377125	2	-	27869803	PATU8988S	viability after 31 days	GGCCCTTTGCTATGGTGGAATGG	XDH	ENSG00000158125	0.15244366578733437	[713]	[282,358,NaN]	2	hSpCas9	negative selection	9904586
31383084	31383107	2	+	27869803	PATU8988S	viability after 31 days	GCTTAGCAACAGCATCCACCAGG	XDH	ENSG00000158125	0.7242410525435007	[345]	[241,209,NaN]	8	hSpCas9	negative selection	9904587
31383754	31383777	2	-	27869803	PATU8988S	viability after 31 days	TCGGTAGAACATGGACCCGACGG	XDH	ENSG00000158125	-0.15786757583744498	[435]	[117,203,NaN]	-2	hSpCas9	negative selection	9904588
31397708	31397731	2	-	27869803	PATU8988S	viability after 31 days	GGAAATCTGTGCCGCTGCACAGG	XDH	ENSG00000158125	-0.47095815004850927	[338]	[126,59,NaN]	-5	hSpCas9	negative selection	9904589
31398634	31398657	2	+	27869803	PATU8988S	viability after 31 days	CATACTCATGACGATGCCAGGGG	XDH	ENSG00000158125	-0.5320475870189453	[530]	[90,216,NaN]	-5	hSpCas9	negative selection	9904590
31403109	31403132	2	-	27869803	PATU8988S	viability after 31 days	AACCAAGCTCGGCTGTGGAGAGG	XDH	ENSG00000158125	0.5614148743473238	[338]	[191,208,NaN]	6	hSpCas9	negative selection	9904591
31377102	31377125	2	-	27869803	HPAFII	viability after 35 days	GGCCCTTTGCTATGGTGGAATGG	XDH	ENSG00000158125	0.3160291655860174	[207]	[68,200,NaN]	2	hSpCas9	negative selection	9987035
31383084	31383107	2	+	27869803	HPAFII	viability after 35 days	GCTTAGCAACAGCATCCACCAGG	XDH	ENSG00000158125	1.303463942971307	[193]	[351,118,NaN]	8	hSpCas9	negative selection	9987036
31383754	31383777	2	-	27869803	HPAFII	viability after 35 days	TCGGTAGAACATGGACCCGACGG	XDH	ENSG00000158125	0.20753257606502812	[239]	[25,268,NaN]	1	hSpCas9	negative selection	9987037
31397708	31397731	2	-	27869803	HPAFII	viability after 35 days	GGAAATCTGTGCCGCTGCACAGG	XDH	ENSG00000158125	1.1010876976488015	[153]	[59,287,NaN]	7	hSpCas9	negative selection	9987038
31398634	31398657	2	+	27869803	HPAFII	viability after 35 days	CATACTCATGACGATGCCAGGGG	XDH	ENSG00000158125	-0.9614375834191081	[279]	[132,4,NaN]	-5	hSpCas9	negative selection	9987039
31403109	31403132	2	-	27869803	HPAFII	viability after 35 days	AACCAAGCTCGGCTGTGGAGAGG	XDH	ENSG00000158125	0.4132414255395531	[154]	[32,184,NaN]	2	hSpCas9	negative selection	9987040
31377102	31377125	2	-	27869803	HPAFII	viability after 31 days	GGCCCTTTGCTATGGTGGAATGG	XDH	ENSG00000158125	0.9028637547382491	[207]	[212,223,NaN]	6	hSpCas9	negative selection	10069484
31383084	31383107	2	+	27869803	HPAFII	viability after 31 days	GCTTAGCAACAGCATCCACCAGG	XDH	ENSG00000158125	1.0307956457765544	[193]	[265,174,NaN]	7	hSpCas9	negative selection	10069485
31383754	31383777	2	-	27869803	HPAFII	viability after 31 days	TCGGTAGAACATGGACCCGACGG	XDH	ENSG00000158125	0.43845910239326646	[239]	[37,339,NaN]	3	hSpCas9	negative selection	10069486
31397708	31397731	2	-	27869803	HPAFII	viability after 31 days	GGAAATCTGTGCCGCTGCACAGG	XDH	ENSG00000158125	1.1952645317752322	[153]	[72,333,NaN]	8	hSpCas9	negative selection	10069487
31398634	31398657	2	+	27869803	HPAFII	viability after 31 days	CATACTCATGACGATGCCAGGGG	XDH	ENSG00000158125	-0.4814895707029154	[279]	[202,13,NaN]	-3	hSpCas9	negative selection	10069488
31403109	31403132	2	-	27869803	HPAFII	viability after 31 days	AACCAAGCTCGGCTGTGGAGAGG	XDH	ENSG00000158125	-0.1731589539156072	[154]	[46,109,NaN]	-1	hSpCas9	negative selection	10069489
31401235	31401258	2	-	28162770	P31FUJ	viability	GAATAGGAAGCACCAAGACGAGG	XDH	ENSG00000158125	-0.017951332090550054	[273]	[317]	0	hSpCas9	negative selection	10266016
31379866	31379889	2	-	28162770	P31FUJ	viability	AGAGATCCCCTACAGCAGGGAGG	XDH	ENSG00000158125	0.47706972886955235	[128]	[210]	5	hSpCas9	negative selection	10266017
31383000	31383023	2	-	28162770	P31FUJ	viability	GAAGCAAGTCAAGTCTGTGGCGG	XDH	ENSG00000158125	0.9245447309484642	[255]	[570]	9	hSpCas9	negative selection	10266018
31337783	31337806	2	+	28162770	P31FUJ	viability	GAAGCAGCCAGGAAGAGGGGCGG	XDH	ENSG00000158125	-1.3466221039715407	[144]	[66]	-7	hSpCas9	negative selection	10266019
31398677	31398700	2	-	28162770	P31FUJ	viability	GAGAGAATTGCCAAAAGCCACGG	XDH	ENSG00000158125	-0.5099117954598953	[102]	[84]	-4	hSpCas9	negative selection	10266020
31397667	31397690	2	-	28162770	P31FUJ	viability	GGGCTTCCGGACCTTTGCCAGGG	XDH	ENSG00000158125	0.3648434113186122	[301]	[456]	4	hSpCas9	negative selection	10266021
31386513	31386536	2	-	28162770	P31FUJ	viability	GAAGCAGCTGCGATTTGAAGGGG	XDH	ENSG00000158125	-0.3848052978594285	[139]	[125]	-3	hSpCas9	negative selection	10266022
31383063	31383086	2	-	28162770	P31FUJ	viability	GCTTCCTGCCCAAAAGACAGAGG	XDH	ENSG00000158125	0.601808148525661	[396]	[707]	7	hSpCas9	negative selection	10266023
31381679	31381702	2	+	28162770	P31FUJ	viability	GTTGAGGTCGGAGATGGGGCTGG	XDH	ENSG00000158125	-0.46940848497052745	[118]	[100]	-4	hSpCas9	negative selection	10266024
31379917	31379940	2	+	28162770	P31FUJ	viability	GCAGGGTCTTTCTGTAGCCAGGG	XDH	ENSG00000158125	0.531767851146429	[527]	[896]	6	hSpCas9	negative selection	10266025
31401235	31401258	2	-	28162770	TF1	viability	GAATAGGAAGCACCAAGACGAGG	XDH	ENSG00000158125	NaN	[NaN]	[263]	1	hSpCas9	negative selection	10435382
31379866	31379889	2	-	28162770	TF1	viability	AGAGATCCCCTACAGCAGGGAGG	XDH	ENSG00000158125	NaN	[NaN]	[123]	1	hSpCas9	negative selection	10435383
31383000	31383023	2	-	28162770	TF1	viability	GAAGCAAGTCAAGTCTGTGGCGG	XDH	ENSG00000158125	NaN	[NaN]	[269]	1	hSpCas9	negative selection	10435384
31337783	31337806	2	+	28162770	TF1	viability	GAAGCAGCCAGGAAGAGGGGCGG	XDH	ENSG00000158125	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10435385
31398677	31398700	2	-	28162770	TF1	viability	GAGAGAATTGCCAAAAGCCACGG	XDH	ENSG00000158125	NaN	[NaN]	[129]	1	hSpCas9	negative selection	10435386
31397667	31397690	2	-	28162770	TF1	viability	GGGCTTCCGGACCTTTGCCAGGG	XDH	ENSG00000158125	NaN	[NaN]	[177]	1	hSpCas9	negative selection	10435387
31386513	31386536	2	-	28162770	TF1	viability	GAAGCAGCTGCGATTTGAAGGGG	XDH	ENSG00000158125	NaN	[NaN]	[44]	1	hSpCas9	negative selection	10435388
31383063	31383086	2	-	28162770	TF1	viability	GCTTCCTGCCCAAAAGACAGAGG	XDH	ENSG00000158125	NaN	[NaN]	[468]	1	hSpCas9	negative selection	10435389
31381679	31381702	2	+	28162770	TF1	viability	GTTGAGGTCGGAGATGGGGCTGG	XDH	ENSG00000158125	NaN	[NaN]	[11]	1	hSpCas9	negative selection	10435390
31379917	31379940	2	+	28162770	TF1	viability	GCAGGGTCTTTCTGTAGCCAGGG	XDH	ENSG00000158125	NaN	[NaN]	[459]	1	hSpCas9	negative selection	10435391
31401235	31401258	2	-	28162770	SKM1	viability	GAATAGGAAGCACCAAGACGAGG	XDH	ENSG00000158125	0.3624228731154218	[65]	[149]	3	hSpCas9	negative selection	10604748
31379866	31379889	2	-	28162770	SKM1	viability	AGAGATCCCCTACAGCAGGGAGG	XDH	ENSG00000158125	0.5565099252317243	[29]	[77]	5	hSpCas9	negative selection	10604749
31383000	31383023	2	-	28162770	SKM1	viability	GAAGCAAGTCAAGTCTGTGGCGG	XDH	ENSG00000158125	0.09999578997672143	[94]	[179]	1	hSpCas9	negative selection	10604750
31337783	31337806	2	+	28162770	SKM1	viability	GAAGCAGCCAGGAAGAGGGGCGG	XDH	ENSG00000158125	-2.1677765348637354	[60]	[23]	-8	hSpCas9	negative selection	10604751
31398677	31398700	2	-	28162770	SKM1	viability	GAGAGAATTGCCAAAAGCCACGG	XDH	ENSG00000158125	1.2543491881081095	[22]	[96]	9	hSpCas9	negative selection	10604752
31397667	31397690	2	-	28162770	SKM1	viability	GGGCTTCCGGACCTTTGCCAGGG	XDH	ENSG00000158125	-0.5000736031346431	[87]	[109]	-4	hSpCas9	negative selection	10604753
31386513	31386536	2	-	28162770	SKM1	viability	GAAGCAGCTGCGATTTGAAGGGG	XDH	ENSG00000158125	1.319354151223536	[16]	[74]	9	hSpCas9	negative selection	10604754
31383063	31383086	2	-	28162770	SKM1	viability	GCTTCCTGCCCAAAAGACAGAGG	XDH	ENSG00000158125	0.6945738277189004	[71]	[205]	6	hSpCas9	negative selection	10604755
31381679	31381702	2	+	28162770	SKM1	viability	GTTGAGGTCGGAGATGGGGCTGG	XDH	ENSG00000158125	-0.2370391973008492	[31]	[47]	-2	hSpCas9	negative selection	10604756
31379917	31379940	2	+	28162770	SKM1	viability	GCAGGGTCTTTCTGTAGCCAGGG	XDH	ENSG00000158125	0.1779983019779945	[121]	[243]	1	hSpCas9	negative selection	10604757
31401235	31401258	2	-	28162770	SKM1	viability	GAATAGGAAGCACCAAGACGAGG	XDH	ENSG00000158125	0.3624228731154218	[65]	[149]	3	hSpCas9	negative selection	10774114
31379866	31379889	2	-	28162770	SKM1	viability	AGAGATCCCCTACAGCAGGGAGG	XDH	ENSG00000158125	0.5565099252317243	[29]	[77]	5	hSpCas9	negative selection	10774115
31383000	31383023	2	-	28162770	SKM1	viability	GAAGCAAGTCAAGTCTGTGGCGG	XDH	ENSG00000158125	0.09999578997672143	[94]	[179]	1	hSpCas9	negative selection	10774116
31337783	31337806	2	+	28162770	SKM1	viability	GAAGCAGCCAGGAAGAGGGGCGG	XDH	ENSG00000158125	-2.1677765348637354	[60]	[23]	-8	hSpCas9	negative selection	10774117
31398677	31398700	2	-	28162770	SKM1	viability	GAGAGAATTGCCAAAAGCCACGG	XDH	ENSG00000158125	1.2543491881081095	[22]	[96]	9	hSpCas9	negative selection	10774118
31397667	31397690	2	-	28162770	SKM1	viability	GGGCTTCCGGACCTTTGCCAGGG	XDH	ENSG00000158125	-0.5000736031346431	[87]	[109]	-4	hSpCas9	negative selection	10774119
31386513	31386536	2	-	28162770	SKM1	viability	GAAGCAGCTGCGATTTGAAGGGG	XDH	ENSG00000158125	1.319354151223536	[16]	[74]	9	hSpCas9	negative selection	10774120
31383063	31383086	2	-	28162770	SKM1	viability	GCTTCCTGCCCAAAAGACAGAGG	XDH	ENSG00000158125	0.6945738277189004	[71]	[205]	6	hSpCas9	negative selection	10774121
31381679	31381702	2	+	28162770	SKM1	viability	GTTGAGGTCGGAGATGGGGCTGG	XDH	ENSG00000158125	-0.2370391973008492	[31]	[47]	-2	hSpCas9	negative selection	10774122
31379917	31379940	2	+	28162770	SKM1	viability	GCAGGGTCTTTCTGTAGCCAGGG	XDH	ENSG00000158125	0.1779983019779945	[121]	[243]	1	hSpCas9	negative selection	10774123
31401235	31401258	2	-	28162770	PL21	viability	GAATAGGAAGCACCAAGACGAGG	XDH	ENSG00000158125	-0.8317092515500198	[228]	[55]	-5	hSpCas9	negative selection	10943480
31379866	31379889	2	-	28162770	PL21	viability	AGAGATCCCCTACAGCAGGGAGG	XDH	ENSG00000158125	0.3861516000992691	[108]	[61]	3	hSpCas9	negative selection	10943481
31383000	31383023	2	-	28162770	PL21	viability	GAAGCAAGTCAAGTCTGTGGCGG	XDH	ENSG00000158125	-1.1960612427766684	[278]	[52]	-7	hSpCas9	negative selection	10943482
31337783	31337806	2	+	28162770	PL21	viability	GAAGCAGCCAGGAAGAGGGGCGG	XDH	ENSG00000158125	-1.0959098485724368	[220]	[44]	-6	hSpCas9	negative selection	10943483
31398677	31398700	2	-	28162770	PL21	viability	GAGAGAATTGCCAAAAGCCACGG	XDH	ENSG00000158125	0.9083734901122102	[141]	[115]	7	hSpCas9	negative selection	10943484
31397667	31397690	2	-	28162770	PL21	viability	GGGCTTCCGGACCTTTGCCAGGG	XDH	ENSG00000158125	0.44462362395133415	[286]	[169]	4	hSpCas9	negative selection	10943485
31386513	31386536	2	-	28162770	PL21	viability	GAAGCAGCTGCGATTTGAAGGGG	XDH	ENSG00000158125	0.27608846772261875	[73]	[38]	2	hSpCas9	negative selection	10943486
31383063	31383086	2	-	28162770	PL21	viability	GCTTCCTGCCCAAAAGACAGAGG	XDH	ENSG00000158125	0.22815399065891673	[305]	[155]	2	hSpCas9	negative selection	10943487
31381679	31381702	2	+	28162770	PL21	viability	GTTGAGGTCGGAGATGGGGCTGG	XDH	ENSG00000158125	-2.1534973401253805	[91]	[8]	-8	hSpCas9	negative selection	10943488
31379917	31379940	2	+	28162770	PL21	viability	GCAGGGTCTTTCTGTAGCCAGGG	XDH	ENSG00000158125	0.4494399092892851	[386]	[229]	4	hSpCas9	negative selection	10943489
31401235	31401258	2	-	28162770	P31FUJ	viability	GAATAGGAAGCACCAAGACGAGG	XDH	ENSG00000158125	-0.017951332090550054	[273]	[317]	0	hSpCas9	negative selection	11112846
31379866	31379889	2	-	28162770	P31FUJ	viability	AGAGATCCCCTACAGCAGGGAGG	XDH	ENSG00000158125	0.47706972886955235	[128]	[210]	5	hSpCas9	negative selection	11112847
31383000	31383023	2	-	28162770	P31FUJ	viability	GAAGCAAGTCAAGTCTGTGGCGG	XDH	ENSG00000158125	0.9245447309484642	[255]	[570]	9	hSpCas9	negative selection	11112848
31337783	31337806	2	+	28162770	P31FUJ	viability	GAAGCAGCCAGGAAGAGGGGCGG	XDH	ENSG00000158125	-1.3466221039715407	[144]	[66]	-7	hSpCas9	negative selection	11112849
31398677	31398700	2	-	28162770	P31FUJ	viability	GAGAGAATTGCCAAAAGCCACGG	XDH	ENSG00000158125	-0.5099117954598953	[102]	[84]	-4	hSpCas9	negative selection	11112850
31397667	31397690	2	-	28162770	P31FUJ	viability	GGGCTTCCGGACCTTTGCCAGGG	XDH	ENSG00000158125	0.3648434113186122	[301]	[456]	4	hSpCas9	negative selection	11112851
31386513	31386536	2	-	28162770	P31FUJ	viability	GAAGCAGCTGCGATTTGAAGGGG	XDH	ENSG00000158125	-0.3848052978594285	[139]	[125]	-3	hSpCas9	negative selection	11112852
31383063	31383086	2	-	28162770	P31FUJ	viability	GCTTCCTGCCCAAAAGACAGAGG	XDH	ENSG00000158125	0.601808148525661	[396]	[707]	7	hSpCas9	negative selection	11112853
31381679	31381702	2	+	28162770	P31FUJ	viability	GTTGAGGTCGGAGATGGGGCTGG	XDH	ENSG00000158125	-0.46940848497052745	[118]	[100]	-4	hSpCas9	negative selection	11112854
31379917	31379940	2	+	28162770	P31FUJ	viability	GCAGGGTCTTTCTGTAGCCAGGG	XDH	ENSG00000158125	0.531767851146429	[527]	[896]	6	hSpCas9	negative selection	11112855
31401235	31401258	2	-	28162770	OCIAML5	viability	GAATAGGAAGCACCAAGACGAGG	XDH	ENSG00000158125	0.8260053342486408	[139]	[447]	7	hSpCas9	negative selection	11282212
31379866	31379889	2	-	28162770	OCIAML5	viability	AGAGATCCCCTACAGCAGGGAGG	XDH	ENSG00000158125	1.2830930124176387	[55]	[245]	9	hSpCas9	negative selection	11282213
31383000	31383023	2	-	28162770	OCIAML5	viability	GAAGCAAGTCAAGTCTGTGGCGG	XDH	ENSG00000158125	-0.5625599536690121	[197]	[241]	-4	hSpCas9	negative selection	11282214
31337783	31337806	2	+	28162770	OCIAML5	viability	GAAGCAGCCAGGAAGAGGGGCGG	XDH	ENSG00000158125	-3.1739946657513594	[99]	[19]	-9	hSpCas9	negative selection	11282215
31398677	31398700	2	-	28162770	OCIAML5	viability	GAGAGAATTGCCAAAAGCCACGG	XDH	ENSG00000158125	0.8427192078099104	[58]	[190]	7	hSpCas9	negative selection	11282216
31397667	31397690	2	-	28162770	OCIAML5	viability	GGGCTTCCGGACCTTTGCCAGGG	XDH	ENSG00000158125	-0.18953551664713764	[174]	[276]	-1	hSpCas9	negative selection	11282217
31386513	31386536	2	-	28162770	OCIAML5	viability	GAAGCAGCTGCGATTTGAAGGGG	XDH	ENSG00000158125	0.17964228886334133	[44]	[91]	1	hSpCas9	negative selection	11282218
31383063	31383086	2	-	28162770	OCIAML5	viability	GCTTCCTGCCCAAAAGACAGAGG	XDH	ENSG00000158125	1.5229728604829278	[143]	[746]	9	hSpCas9	negative selection	11282219
31381679	31381702	2	+	28162770	OCIAML5	viability	GTTGAGGTCGGAGATGGGGCTGG	XDH	ENSG00000158125	-4.617601317226974	[67]	[4]	-9	hSpCas9	negative selection	11282220
31379917	31379940	2	+	28162770	OCIAML5	viability	GCAGGGTCTTTCTGTAGCCAGGG	XDH	ENSG00000158125	0.48592989265101894	[249]	[631]	4	hSpCas9	negative selection	11282221
31401235	31401258	2	-	28162770	EOL1	viability	GAATAGGAAGCACCAAGACGAGG	XDH	ENSG00000158125	0.7775903316753489	[443]	[400]	6	hSpCas9	negative selection	11451578
31379866	31379889	2	-	28162770	EOL1	viability	AGAGATCCCCTACAGCAGGGAGG	XDH	ENSG00000158125	0.21732952079838042	[159]	[97]	2	hSpCas9	negative selection	11451579
31383000	31383023	2	-	28162770	EOL1	viability	GAAGCAAGTCAAGTCTGTGGCGG	XDH	ENSG00000158125	-0.1022191379922508	[543]	[266]	-1	hSpCas9	negative selection	11451580
31337783	31337806	2	+	28162770	EOL1	viability	GAAGCAGCCAGGAAGAGGGGCGG	XDH	ENSG00000158125	-1.1794031924683739	[373]	[86]	-7	hSpCas9	negative selection	11451581
31398677	31398700	2	-	28162770	EOL1	viability	GAGAGAATTGCCAAAAGCCACGG	XDH	ENSG00000158125	1.653586449965112	[218]	[362]	9	hSpCas9	negative selection	11451582
31397667	31397690	2	-	28162770	EOL1	viability	GGGCTTCCGGACCTTTGCCAGGG	XDH	ENSG00000158125	0.6497908807121993	[518]	[428]	6	hSpCas9	negative selection	11451583
31386513	31386536	2	-	28162770	EOL1	viability	GAAGCAGCTGCGATTTGAAGGGG	XDH	ENSG00000158125	0.5197060393975794	[93]	[70]	5	hSpCas9	negative selection	11451584
31383063	31383086	2	-	28162770	EOL1	viability	GCTTCCTGCCCAAAAGACAGAGG	XDH	ENSG00000158125	0.7399400126935571	[357]	[314]	6	hSpCas9	negative selection	11451585
31381679	31381702	2	+	28162770	EOL1	viability	GTTGAGGTCGGAGATGGGGCTGG	XDH	ENSG00000158125	-1.9499213463456064	[131]	[17]	-8	hSpCas9	negative selection	11451586
31379917	31379940	2	+	28162770	EOL1	viability	GCAGGGTCTTTCTGTAGCCAGGG	XDH	ENSG00000158125	-0.020553982280567817	[592]	[307]	0	hSpCas9	negative selection	11451587
31401235	31401258	2	-	28162770	MOLM13	viability	GAATAGGAAGCACCAAGACGAGG	XDH	ENSG00000158125	1.3934394323846977	[337]	[641]	9	hSpCas9	negative selection	11620944
31379866	31379889	2	-	28162770	MOLM13	viability	AGAGATCCCCTACAGCAGGGAGG	XDH	ENSG00000158125	0.0726603633459153	[216]	[164]	0	hSpCas9	negative selection	11620945
31383000	31383023	2	-	28162770	MOLM13	viability	GAAGCAAGTCAAGTCTGTGGCGG	XDH	ENSG00000158125	0.7926999849650624	[399]	[500]	6	hSpCas9	negative selection	11620946
31337783	31337806	2	+	28162770	MOLM13	viability	GAAGCAGCCAGGAAGAGGGGCGG	XDH	ENSG00000158125	-2.738962188896091	[276]	[29]	-8	hSpCas9	negative selection	11620947
31398677	31398700	2	-	28162770	MOLM13	viability	GAGAGAATTGCCAAAAGCCACGG	XDH	ENSG00000158125	1.5372630845852406	[202]	[425]	9	hSpCas9	negative selection	11620948
31397667	31397690	2	-	28162770	MOLM13	viability	GGGCTTCCGGACCTTTGCCAGGG	XDH	ENSG00000158125	0.46788938154457893	[361]	[361]	3	hSpCas9	negative selection	11620949
31386513	31386536	2	-	28162770	MOLM13	viability	GAAGCAGCTGCGATTTGAAGGGG	XDH	ENSG00000158125	1.5482627980085986	[95]	[202]	9	hSpCas9	negative selection	11620950
31383063	31383086	2	-	28162770	MOLM13	viability	GCTTCCTGCCCAAAAGACAGAGG	XDH	ENSG00000158125	0.47499626803883876	[404]	[406]	3	hSpCas9	negative selection	11620951
31381679	31381702	2	+	28162770	MOLM13	viability	GTTGAGGTCGGAGATGGGGCTGG	XDH	ENSG00000158125	-2.833280153175986	[137]	[13]	-8	hSpCas9	negative selection	11620952
31379917	31379940	2	+	28162770	MOLM13	viability	GCAGGGTCTTTCTGTAGCCAGGG	XDH	ENSG00000158125	0.7761915304309097	[616]	[763]	6	hSpCas9	negative selection	11620953
31401235	31401258	2	-	28162770	HEL	viability	GAATAGGAAGCACCAAGACGAGG	XDH	ENSG00000158125	0.4792400997174776	[279]	[249]	4	hSpCas9	negative selection	11790310
31379866	31379889	2	-	28162770	HEL	viability	AGAGATCCCCTACAGCAGGGAGG	XDH	ENSG00000158125	0.7838311512349568	[145]	[160]	6	hSpCas9	negative selection	11790311
31383000	31383023	2	-	28162770	HEL	viability	GAAGCAAGTCAAGTCTGTGGCGG	XDH	ENSG00000158125	0.9624513722558908	[390]	[487]	8	hSpCas9	negative selection	11790312
31337783	31337806	2	+	28162770	HEL	viability	GAAGCAGCCAGGAAGAGGGGCGG	XDH	ENSG00000158125	-1.1906112985901915	[195]	[54]	-6	hSpCas9	negative selection	11790313
31398677	31398700	2	-	28162770	HEL	viability	GAGAGAATTGCCAAAAGCCACGG	XDH	ENSG00000158125	0.00348617577824728	[175]	[112]	0	hSpCas9	negative selection	11790314
31397667	31397690	2	-	28162770	HEL	viability	GGGCTTCCGGACCTTTGCCAGGG	XDH	ENSG00000158125	1.020930602677477	[346]	[450]	8	hSpCas9	negative selection	11790315
31386513	31386536	2	-	28162770	HEL	viability	GAAGCAGCTGCGATTTGAAGGGG	XDH	ENSG00000158125	0.46586106991627774	[77]	[68]	4	hSpCas9	negative selection	11790316
31383063	31383086	2	-	28162770	HEL	viability	GCTTCCTGCCCAAAAGACAGAGG	XDH	ENSG00000158125	0.08352174411575652	[360]	[244]	0	hSpCas9	negative selection	11790317
31381679	31381702	2	+	28162770	HEL	viability	GTTGAGGTCGGAGATGGGGCTGG	XDH	ENSG00000158125	-2.9719710121148513	[97]	[7]	-8	hSpCas9	negative selection	11790318
31379917	31379940	2	+	28162770	HEL	viability	GCAGGGTCTTTCTGTAGCCAGGG	XDH	ENSG00000158125	-0.12583345887640496	[522]	[306]	-1	hSpCas9	negative selection	11790319
31401235	31401258	2	-	28162770	MV411	viability	GAATAGGAAGCACCAAGACGAGG	XDH	ENSG00000158125	0.6521920767997582	[175]	[232]	6	hSpCas9	negative selection	11959676
31379866	31379889	2	-	28162770	MV411	viability	AGAGATCCCCTACAGCAGGGAGG	XDH	ENSG00000158125	0.7926737731883207	[134]	[196]	7	hSpCas9	negative selection	11959677
31383000	31383023	2	-	28162770	MV411	viability	GAAGCAAGTCAAGTCTGTGGCGG	XDH	ENSG00000158125	1.2606370485376346	[271]	[548]	9	hSpCas9	negative selection	11959678
31337783	31337806	2	+	28162770	MV411	viability	GAAGCAGCCAGGAAGAGGGGCGG	XDH	ENSG00000158125	-1.7947319034611644	[242]	[58]	-8	hSpCas9	negative selection	11959679
31398677	31398700	2	-	28162770	MV411	viability	GAGAGAATTGCCAAAAGCCACGG	XDH	ENSG00000158125	-0.11934477988884745	[146]	[113]	-1	hSpCas9	negative selection	11959680
31397667	31397690	2	-	28162770	MV411	viability	GGGCTTCCGGACCTTTGCCAGGG	XDH	ENSG00000158125	-0.19956767715470436	[288]	[211]	-1	hSpCas9	negative selection	11959681
31386513	31386536	2	-	28162770	MV411	viability	GAAGCAGCTGCGATTTGAAGGGG	XDH	ENSG00000158125	-0.7525624492172245	[83]	[41]	-5	hSpCas9	negative selection	11959682
31383063	31383086	2	-	28162770	MV411	viability	GCTTCCTGCCCAAAAGACAGAGG	XDH	ENSG00000158125	0.4999442447126581	[297]	[354]	4	hSpCas9	negative selection	11959683
31381679	31381702	2	+	28162770	MV411	viability	GTTGAGGTCGGAGATGGGGCTGG	XDH	ENSG00000158125	-1.2413096346790775	[86]	[30]	-7	hSpCas9	negative selection	11959684
31379917	31379940	2	+	28162770	MV411	viability	GCAGGGTCTTTCTGTAGCCAGGG	XDH	ENSG00000158125	0.7108380716230183	[395]	[545]	6	hSpCas9	negative selection	11959685
31401235	31401258	2	-	28162770	MONOMAC1	viability	GAATAGGAAGCACCAAGACGAGG	XDH	ENSG00000158125	-0.16497563782725522	[177]	[181]	-1	hSpCas9	negative selection	12129042
31379866	31379889	2	-	28162770	MONOMAC1	viability	AGAGATCCCCTACAGCAGGGAGG	XDH	ENSG00000158125	0.6355064070888835	[72]	[129]	6	hSpCas9	negative selection	12129043
31383000	31383023	2	-	28162770	MONOMAC1	viability	GAAGCAAGTCAAGTCTGTGGCGG	XDH	ENSG00000158125	-0.23613666674849398	[186]	[181]	-2	hSpCas9	negative selection	12129044
31337783	31337806	2	+	28162770	MONOMAC1	viability	GAAGCAGCCAGGAAGAGGGGCGG	XDH	ENSG00000158125	-1.4194292683960015	[118]	[50]	-8	hSpCas9	negative selection	12129045
31398677	31398700	2	-	28162770	MONOMAC1	viability	GAGAGAATTGCCAAAAGCCACGG	XDH	ENSG00000158125	-0.35669351304803903	[104]	[93]	-3	hSpCas9	negative selection	12129046
31397667	31397690	2	-	28162770	MONOMAC1	viability	GGGCTTCCGGACCTTTGCCAGGG	XDH	ENSG00000158125	0.8416436211045062	[183]	[377]	7	hSpCas9	negative selection	12129047
31386513	31386536	2	-	28162770	MONOMAC1	viability	GAAGCAGCTGCGATTTGAAGGGG	XDH	ENSG00000158125	0.9473530622756209	[37]	[83]	8	hSpCas9	negative selection	12129048
31383063	31383086	2	-	28162770	MONOMAC1	viability	GCTTCCTGCCCAAAAGACAGAGG	XDH	ENSG00000158125	0.8371113753522921	[166]	[341]	7	hSpCas9	negative selection	12129049
31381679	31381702	2	+	28162770	MONOMAC1	viability	GTTGAGGTCGGAGATGGGGCTGG	XDH	ENSG00000158125	-1.3125140644794895	[38]	[17]	-7	hSpCas9	negative selection	12129050
31379917	31379940	2	+	28162770	MONOMAC1	viability	GCAGGGTCTTTCTGTAGCCAGGG	XDH	ENSG00000158125	0.20521449726344665	[254]	[336]	2	hSpCas9	negative selection	12129051
31401235	31401258	2	-	28162770	OCIAML2	viability	GAATAGGAAGCACCAAGACGAGG	XDH	ENSG00000158125	0.30321583462519175	[55]	[382]	3	hSpCas9	negative selection	12298408
31379866	31379889	2	-	28162770	OCIAML2	viability	AGAGATCCCCTACAGCAGGGAGG	XDH	ENSG00000158125	0.6107585015984938	[27]	[236]	6	hSpCas9	negative selection	12298409
31383000	31383023	2	-	28162770	OCIAML2	viability	GAAGCAAGTCAAGTCTGTGGCGG	XDH	ENSG00000158125	0.679117294262521	[47]	[425]	6	hSpCas9	negative selection	12298410
31337783	31337806	2	+	28162770	OCIAML2	viability	GAAGCAGCCAGGAAGAGGGGCGG	XDH	ENSG00000158125	-4.718557338685747	[37]	[7]	-9	hSpCas9	negative selection	12298411
31398677	31398700	2	-	28162770	OCIAML2	viability	GAGAGAATTGCCAAAAGCCACGG	XDH	ENSG00000158125	0.43207297340292383	[22]	[171]	4	hSpCas9	negative selection	12298412
31397667	31397690	2	-	28162770	OCIAML2	viability	GGGCTTCCGGACCTTTGCCAGGG	XDH	ENSG00000158125	0.7634255136198669	[43]	[413]	7	hSpCas9	negative selection	12298413
31386513	31386536	2	-	28162770	OCIAML2	viability	GAAGCAGCTGCGATTTGAAGGGG	XDH	ENSG00000158125	1.1732263645325633	[7]	[99]	9	hSpCas9	negative selection	12298414
31383063	31383086	2	-	28162770	OCIAML2	viability	GCTTCCTGCCCAAAAGACAGAGG	XDH	ENSG00000158125	1.0505175778815516	[51]	[596]	8	hSpCas9	negative selection	12298415
31381679	31381702	2	+	28162770	OCIAML2	viability	GTTGAGGTCGGAGATGGGGCTGG	XDH	ENSG00000158125	-0.8267736354674367	[7]	[24]	-5	hSpCas9	negative selection	12298416
31379917	31379940	2	+	28162770	OCIAML2	viability	GCAGGGTCTTTCTGTAGCCAGGG	XDH	ENSG00000158125	0.7783667471913502	[70]	[674]	7	hSpCas9	negative selection	12298417
31401235	31401258	2	-	28162770	OCIAML3	viability	GAATAGGAAGCACCAAGACGAGG	XDH	ENSG00000158125	0.17910695731500836	[66]	[228]	1	hSpCas9	negative selection	12467774
31379866	31379889	2	-	28162770	OCIAML3	viability	AGAGATCCCCTACAGCAGGGAGG	XDH	ENSG00000158125	-0.15148940462321225	[38]	[105]	-1	hSpCas9	negative selection	12467775
31383000	31383023	2	-	28162770	OCIAML3	viability	GAAGCAAGTCAAGTCTGTGGCGG	XDH	ENSG00000158125	-0.2060819866625606	[93]	[245]	-2	hSpCas9	negative selection	12467776
31337783	31337806	2	+	28162770	OCIAML3	viability	GAAGCAGCCAGGAAGAGGGGCGG	XDH	ENSG00000158125	-1.6935433138750775	[44]	[41]	-8	hSpCas9	negative selection	12467777
31398677	31398700	2	-	28162770	OCIAML3	viability	GAGAGAATTGCCAAAAGCCACGG	XDH	ENSG00000158125	-0.45265179107862163	[33]	[74]	-3	hSpCas9	negative selection	12467778
31397667	31397690	2	-	28162770	OCIAML3	viability	GGGCTTCCGGACCTTTGCCAGGG	XDH	ENSG00000158125	0.43701925529646135	[68]	[281]	4	hSpCas9	negative selection	12467779
31386513	31386536	2	-	28162770	OCIAML3	viability	GAAGCAGCTGCGATTTGAAGGGG	XDH	ENSG00000158125	-1.857042046157957	[29]	[24]	-8	hSpCas9	negative selection	12467780
31383063	31383086	2	-	28162770	OCIAML3	viability	GCTTCCTGCCCAAAAGACAGAGG	XDH	ENSG00000158125	0.6809994071757067	[74]	[362]	6	hSpCas9	negative selection	12467781
31381679	31381702	2	+	28162770	OCIAML3	viability	GTTGAGGTCGGAGATGGGGCTGG	XDH	ENSG00000158125	-0.33766788706437767	[17]	[42]	-3	hSpCas9	negative selection	12467782
31379917	31379940	2	+	28162770	OCIAML3	viability	GCAGGGTCTTTCTGTAGCCAGGG	XDH	ENSG00000158125	0.133912814239036	[143]	[476]	1	hSpCas9	negative selection	12467783