Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 10413
• Symbol: YAP1
• Description: Yes1 associated transcriptional regulator

DataSource: http://genomecrispr.dkfz.de/#!/results/YAP1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
102205946	102205969	11	+	26472758	Jiyoye	viability	GCTCCCCAGAGCCCACAGGGAGG	YAP1	ENSG00000137693	-0.9788830508012045	[114]	[43]	-6	hSpCas9	negative selection	183011
102223646	102223669	11	+	26472758	Jiyoye	viability	CCAACACTGGAGCAGGATGGTGG	YAP1	ENSG00000137693	-1.3654141223910539	[40]	[11]	-7	hSpCas9	negative selection	183012
102206014	102206037	11	+	26472758	Jiyoye	viability	GCAGCAACTGCAGATGGAGAAGG	YAP1	ENSG00000137693	4.992137882227029	[0]	[23]	9	hSpCas9	negative selection	183013
102162458	102162481	11	+	26472758	Jiyoye	viability	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	-4.236680808268852	[24]	[0]	-9	hSpCas9	negative selection	183014
102205958	102205981	11	-	26472758	Jiyoye	viability	CCACCCATGACGCCTCCCTGTGG	YAP1	ENSG00000137693	0.9388958609500502	[275]	[398]	6	hSpCas9	negative selection	183015
102162486	102162509	11	-	26472758	Jiyoye	viability	GGGACAGCATGGCCTTCCTGGGG	YAP1	ENSG00000137693	0.2590767425167395	[40]	[36]	2	hSpCas9	negative selection	183016
102206025	102206048	11	+	26472758	Jiyoye	viability	AGATGGAGAAGGAGAGGCTGCGG	YAP1	ENSG00000137693	-1.6203053549162338	[105]	[25]	-8	hSpCas9	negative selection	183017
102223630	102223653	11	-	26472758	Jiyoye	viability	GTGTTGGTAACTGGCTACGCAGG	YAP1	ENSG00000137693	0.7989431014618701	[124]	[163]	5	hSpCas9	negative selection	183018
102205993	102206016	11	-	26472758	Jiyoye	viability	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	0.880629567010039	[120]	[167]	6	hSpCas9	negative selection	183019
102206053	102206076	11	+	26472758	Jiyoye	viability	ACAGCAAGAACTGCTTCGGCAGG	YAP1	ENSG00000137693	0.2816444994220144	[23]	[21]	2	hSpCas9	negative selection	183020
102205946	102205969	11	+	26472758	KBM7	viability	GCTCCCCAGAGCCCACAGGGAGG	YAP1	ENSG00000137693	-0.6891209558819685	[435,369]	[114,118]	-5	hSpCas9	negative selection	374129
102223646	102223669	11	+	26472758	KBM7	viability	CCAACACTGGAGCAGGATGGTGG	YAP1	ENSG00000137693	0.19600564694453526	[152,119]	[82,63]	2	hSpCas9	negative selection	374130
102206014	102206037	11	+	26472758	KBM7	viability	GCAGCAACTGCAGATGGAGAAGG	YAP1	ENSG00000137693	0.43348493677707545	[121,165]	[77,106]	4	hSpCas9	negative selection	374131
102162458	102162481	11	+	26472758	KBM7	viability	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	0.709763108271761	[37,34]	[16,37]	7	hSpCas9	negative selection	374132
102205958	102205981	11	-	26472758	KBM7	viability	CCACCCATGACGCCTCCCTGTGG	YAP1	ENSG00000137693	0.8156017263743263	[1578,1301]	[1390,1002]	8	hSpCas9	negative selection	374133
102162486	102162509	11	-	26472758	KBM7	viability	GGGACAGCATGGCCTTCCTGGGG	YAP1	ENSG00000137693	-0.4618921199303714	[197,173]	[74,52]	-4	hSpCas9	negative selection	374134
102206025	102206048	11	+	26472758	KBM7	viability	AGATGGAGAAGGAGAGGCTGCGG	YAP1	ENSG00000137693	-0.8392895986540059	[515,545]	[175,108]	-6	hSpCas9	negative selection	374135
102223630	102223653	11	-	26472758	KBM7	viability	GTGTTGGTAACTGGCTACGCAGG	YAP1	ENSG00000137693	0.7286829265510274	[797,736]	[494,690]	7	hSpCas9	negative selection	374136
102205993	102206016	11	-	26472758	KBM7	viability	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	0.4612492654063079	[587,713]	[462,395]	5	hSpCas9	negative selection	374137
102206053	102206076	11	+	26472758	KBM7	viability	ACAGCAAGAACTGCTTCGGCAGG	YAP1	ENSG00000137693	-0.020830785765462045	[192,305]	[92,141]	0	hSpCas9	negative selection	374138
102205946	102205969	11	+	26472758	Raji	viability	GCTCCCCAGAGCCCACAGGGAGG	YAP1	ENSG00000137693	-2.352048083263698	[197]	[8]	-9	hSpCas9	negative selection	565247
102223646	102223669	11	+	26472758	Raji	viability	CCAACACTGGAGCAGGATGGTGG	YAP1	ENSG00000137693	0.1625250895660606	[76]	[19]	1	hSpCas9	negative selection	565248
102206014	102206037	11	+	26472758	Raji	viability	GCAGCAACTGCAGATGGAGAAGG	YAP1	ENSG00000137693	-1.5364726544011251	[49]	[3]	-8	hSpCas9	negative selection	565249
102162458	102162481	11	+	26472758	Raji	viability	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	1.8443491295398058	[11]	[9]	9	hSpCas9	negative selection	565250
102205958	102205981	11	-	26472758	Raji	viability	CCACCCATGACGCCTCCCTGTGG	YAP1	ENSG00000137693	0.19423394929339843	[692]	[183]	1	hSpCas9	negative selection	565251
102162486	102162509	11	-	26472758	Raji	viability	GGGACAGCATGGCCTTCCTGGGG	YAP1	ENSG00000137693	-0.6999713866840045	[146]	[20]	-5	hSpCas9	negative selection	565252
102206025	102206048	11	+	26472758	Raji	viability	AGATGGAGAAGGAGAGGCTGCGG	YAP1	ENSG00000137693	-1.3809029459358828	[302]	[26]	-7	hSpCas9	negative selection	565253
102223630	102223653	11	-	26472758	Raji	viability	GTGTTGGTAACTGGCTACGCAGG	YAP1	ENSG00000137693	0.28693295570431204	[331]	[93]	2	hSpCas9	negative selection	565254
102205993	102206016	11	-	26472758	Raji	viability	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	0.283413899465099	[261]	[73]	2	hSpCas9	negative selection	565255
102206053	102206076	11	+	26472758	Raji	viability	ACAGCAAGAACTGCTTCGGCAGG	YAP1	ENSG00000137693	-0.21454455951376294	[114]	[22]	-2	hSpCas9	negative selection	565256
102205946	102205969	11	+	26472758	K562	viability	GCTCCCCAGAGCCCACAGGGAGG	YAP1	ENSG00000137693	-2.097973469780631	[425]	[83]	-7	hSpCas9	negative selection	756365
102223646	102223669	11	+	26472758	K562	viability	CCAACACTGGAGCAGGATGGTGG	YAP1	ENSG00000137693	0.15647102839074412	[185]	[174]	1	hSpCas9	negative selection	756366
102206014	102206037	11	+	26472758	K562	viability	GCAGCAACTGCAGATGGAGAAGG	YAP1	ENSG00000137693	-1.2701544451633116	[119]	[41]	-6	hSpCas9	negative selection	756367
102162458	102162481	11	+	26472758	K562	viability	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	0.8897538463670847	[38]	[60]	7	hSpCas9	negative selection	756368
102205958	102205981	11	-	26472758	K562	viability	CCACCCATGACGCCTCCCTGTGG	YAP1	ENSG00000137693	0.3047683835812789	[1029]	[1073]	2	hSpCas9	negative selection	756369
102162486	102162509	11	-	26472758	K562	viability	GGGACAGCATGGCCTTCCTGGGG	YAP1	ENSG00000137693	-0.5362682439290776	[133]	[77]	-3	hSpCas9	negative selection	756370
102206025	102206048	11	+	26472758	K562	viability	AGATGGAGAAGGAGAGGCTGCGG	YAP1	ENSG00000137693	-2.7162070339994084	[505]	[64]	-8	hSpCas9	negative selection	756371
102223630	102223653	11	-	26472758	K562	viability	GTGTTGGTAACTGGCTACGCAGG	YAP1	ENSG00000137693	0.13008605218745173	[629]	[581]	0	hSpCas9	negative selection	756372
102205993	102206016	11	-	26472758	K562	viability	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	1.0565416814013926	[560]	[984]	8	hSpCas9	negative selection	756373
102206053	102206076	11	+	26472758	K562	viability	ACAGCAAGAACTGCTTCGGCAGG	YAP1	ENSG00000137693	-0.141859778630973	[148]	[113]	-1	hSpCas9	negative selection	756374
102110992	102111015	11	-	26627737	DLD1	viability	GCACGATCTGATGCCCGGCGGGG	YAP1	ENSG00000137693	-1.9514848826668336	[1239]	[20,58,202]	-8	hSpCas9	negative selection	776407
102111003	102111026	11	+	26627737	DLD1	viability	ATCAGATCGTGCACGTCCGCGGG	YAP1	ENSG00000137693	-3.1835615854958776	[762]	[0,23,49]	-9	hSpCas9	negative selection	776408
102111157	102111180	11	-	26627737	DLD1	viability	ACGAGGTTACCTGTCGGGAGTGG	YAP1	ENSG00000137693	-2.2489495857724897	[246]	[13,36,0]	-9	hSpCas9	negative selection	776409
102162497	102162520	11	-	26627737	DLD1	viability	GACGTTCATCTGGGACAGCATGG	YAP1	ENSG00000137693	-1.8267781199771258	[446]	[27,23,61]	-8	hSpCas9	negative selection	776410
102229724	102229747	11	-	26627737	DLD1	viability	AACGGTTCTGCTGTGAGGGCAGG	YAP1	ENSG00000137693	0.8360777168711722	[88]	[22,81,45]	7	hSpCas9	negative selection	776411
102110992	102111015	11	-	26627737	GBM cells	viability after 5 days	GCACGATCTGATGCCCGGCGGGG	YAP1	ENSG00000137693	0.6085030301205869	[265]	[183,250]	8	hSpCas9	negative selection	858722
102111003	102111026	11	+	26627737	GBM cells	viability after 5 days	ATCAGATCGTGCACGTCCGCGGG	YAP1	ENSG00000137693	-0.042590475804169914	[289]	[165,135]	0	hSpCas9	negative selection	858723
102111157	102111180	11	-	26627737	GBM cells	viability after 5 days	ACGAGGTTACCTGTCGGGAGTGG	YAP1	ENSG00000137693	-0.23709281832269077	[288]	[150,111]	-4	hSpCas9	negative selection	858724
102162497	102162520	11	-	26627737	GBM cells	viability after 5 days	GACGTTCATCTGGGACAGCATGG	YAP1	ENSG00000137693	0.15086041323566185	[282]	[174,161]	2	hSpCas9	negative selection	858725
102229724	102229747	11	-	26627737	GBM cells	viability after 5 days	AACGGTTCTGCTGTGAGGGCAGG	YAP1	ENSG00000137693	0.24849831267591305	[61]	[39,38]	4	hSpCas9	negative selection	858726
102110992	102111015	11	-	26627737	GBM cells	viability after 13 days	GCACGATCTGATGCCCGGCGGGG	YAP1	ENSG00000137693	0.9251237542085344	[265]	[235,304]	9	hSpCas9	negative selection	941037
102111003	102111026	11	+	26627737	GBM cells	viability after 13 days	ATCAGATCGTGCACGTCCGCGGG	YAP1	ENSG00000137693	0.24431549250702322	[289]	[192,180]	3	hSpCas9	negative selection	941038
102111157	102111180	11	-	26627737	GBM cells	viability after 13 days	ACGAGGTTACCTGTCGGGAGTGG	YAP1	ENSG00000137693	0.24707748471002217	[288]	[243,138]	3	hSpCas9	negative selection	941039
102162497	102162520	11	-	26627737	GBM cells	viability after 13 days	GACGTTCATCTGGGACAGCATGG	YAP1	ENSG00000137693	0.6098934381614413	[282]	[294,184]	7	hSpCas9	negative selection	941040
102229724	102229747	11	-	26627737	GBM cells	viability after 13 days	AACGGTTCTGCTGTGAGGGCAGG	YAP1	ENSG00000137693	-0.47261785638837983	[61]	[26,21]	-5	hSpCas9	negative selection	941041
102110992	102111015	11	-	26627737	GBM cells	viability after 21 days	GCACGATCTGATGCCCGGCGGGG	YAP1	ENSG00000137693	1.5591335824334138	[265]	[452,400]	9	hSpCas9	negative selection	1023352
102111003	102111026	11	+	26627737	GBM cells	viability after 21 days	ATCAGATCGTGCACGTCCGCGGG	YAP1	ENSG00000137693	0.5903519875454813	[289]	[243,230]	6	hSpCas9	negative selection	1023353
102111157	102111180	11	-	26627737	GBM cells	viability after 21 days	ACGAGGTTACCTGTCGGGAGTGG	YAP1	ENSG00000137693	-0.10750529282163428	[288]	[151,139]	-1	hSpCas9	negative selection	1023354
102162497	102162520	11	-	26627737	GBM cells	viability after 21 days	GACGTTCATCTGGGACAGCATGG	YAP1	ENSG00000137693	0.757757897052071	[282]	[295,226]	7	hSpCas9	negative selection	1023355
102229724	102229747	11	-	26627737	GBM cells	viability after 21 days	AACGGTTCTGCTGTGAGGGCAGG	YAP1	ENSG00000137693	-0.4352455442954648	[61]	[26,22]	-4	hSpCas9	negative selection	1023356
102110992	102111015	11	-	26627737	RPE1	viability after 9 days	GCACGATCTGATGCCCGGCGGGG	YAP1	ENSG00000137693	-0.8422215671914912	[737]	[96,169]	-6	hSpCas9	negative selection	1105667
102111003	102111026	11	+	26627737	RPE1	viability after 9 days	ATCAGATCGTGCACGTCCGCGGG	YAP1	ENSG00000137693	1.912315088859236	[165]	[68,358]	8	hSpCas9	negative selection	1105668
102111157	102111180	11	-	26627737	RPE1	viability after 9 days	ACGAGGTTACCTGTCGGGAGTGG	YAP1	ENSG00000137693	-0.19602280476099565	[405]	[58,177]	-1	hSpCas9	negative selection	1105669
102162497	102162520	11	-	26627737	RPE1	viability after 9 days	GACGTTCATCTGGGACAGCATGG	YAP1	ENSG00000137693	-0.6024342868944441	[869]	[188,166]	-4	hSpCas9	negative selection	1105670
102229724	102229747	11	-	26627737	RPE1	viability after 9 days	AACGGTTCTGCTGTGAGGGCAGG	YAP1	ENSG00000137693	-2.293958971802212	[459]	[24,34]	-9	hSpCas9	negative selection	1105671
102110992	102111015	11	-	26627737	RPE1	viability after 12 days	GCACGATCTGATGCCCGGCGGGG	YAP1	ENSG00000137693	-1.3234167102927459	[737]	[86,70]	-7	hSpCas9	negative selection	1187982
102111003	102111026	11	+	26627737	RPE1	viability after 12 days	ATCAGATCGTGCACGTCCGCGGG	YAP1	ENSG00000137693	1.3035554340407964	[165]	[61,160]	7	hSpCas9	negative selection	1187983
102111157	102111180	11	-	26627737	RPE1	viability after 12 days	ACGAGGTTACCTGTCGGGAGTGG	YAP1	ENSG00000137693	-0.5748897591654275	[405]	[12,136]	-4	hSpCas9	negative selection	1187984
102162497	102162520	11	-	26627737	RPE1	viability after 12 days	GACGTTCATCTGGGACAGCATGG	YAP1	ENSG00000137693	-0.728039942629475	[869]	[144,136]	-5	hSpCas9	negative selection	1187985
102229724	102229747	11	-	26627737	RPE1	viability after 12 days	AACGGTTCTGCTGTGAGGGCAGG	YAP1	ENSG00000137693	-1.5453319239103704	[459]	[53,29]	-8	hSpCas9	negative selection	1187986
102110992	102111015	11	-	26627737	RPE1	viability after 15 days	GCACGATCTGATGCCCGGCGGGG	YAP1	ENSG00000137693	-1.6826072812790671	[737]	[34,93]	-7	hSpCas9	negative selection	1270297
102111003	102111026	11	+	26627737	RPE1	viability after 15 days	ATCAGATCGTGCACGTCCGCGGG	YAP1	ENSG00000137693	0.4685750118439518	[165]	[9,117]	3	hSpCas9	negative selection	1270298
102111157	102111180	11	-	26627737	RPE1	viability after 15 days	ACGAGGTTACCTGTCGGGAGTGG	YAP1	ENSG00000137693	-1.648496028010403	[405]	[0,70]	-7	hSpCas9	negative selection	1270299
102162497	102162520	11	-	26627737	RPE1	viability after 15 days	GACGTTCATCTGGGACAGCATGG	YAP1	ENSG00000137693	-0.49008491304752927	[869]	[218,132]	-3	hSpCas9	negative selection	1270300
102229724	102229747	11	-	26627737	RPE1	viability after 15 days	AACGGTTCTGCTGTGAGGGCAGG	YAP1	ENSG00000137693	-2.58945259800758	[459]	[42,0]	-8	hSpCas9	negative selection	1270301
102110992	102111015	11	-	26627737	RPE1	viability after 18 days	GCACGATCTGATGCCCGGCGGGG	YAP1	ENSG00000137693	-2.6252570178281234	[737]	[54,7]	-8	hSpCas9	negative selection	1352612
102111003	102111026	11	+	26627737	RPE1	viability after 18 days	ATCAGATCGTGCACGTCCGCGGG	YAP1	ENSG00000137693	1.2024563992545276	[165]	[32,177]	7	hSpCas9	negative selection	1352613
102111157	102111180	11	-	26627737	RPE1	viability after 18 days	ACGAGGTTACCTGTCGGGAGTGG	YAP1	ENSG00000137693	0.4457476595476207	[405]	[155,141]	3	hSpCas9	negative selection	1352614
102162497	102162520	11	-	26627737	RPE1	viability after 18 days	GACGTTCATCTGGGACAGCATGG	YAP1	ENSG00000137693	-1.8340243052546088	[869]	[46,85]	-8	hSpCas9	negative selection	1352615
102229724	102229747	11	-	26627737	RPE1	viability after 18 days	AACGGTTCTGCTGTGAGGGCAGG	YAP1	ENSG00000137693	-2.625712038636053	[459]	[37,0]	-8	hSpCas9	negative selection	1352616
102110992	102111015	11	-	26627737	HeLa	viability after 8 days	GCACGATCTGATGCCCGGCGGGG	YAP1	ENSG00000137693	-0.6048655521521729	[718]	[399,99,162]	-5	hSpCas9	negative selection	1434927
102111003	102111026	11	+	26627737	HeLa	viability after 8 days	ATCAGATCGTGCACGTCCGCGGG	YAP1	ENSG00000137693	-1.373364947983093	[566]	[25,97,142]	-8	hSpCas9	negative selection	1434928
102111157	102111180	11	-	26627737	HeLa	viability after 8 days	ACGAGGTTACCTGTCGGGAGTGG	YAP1	ENSG00000137693	-1.2126703866156632	[438]	[45,121,71]	-8	hSpCas9	negative selection	1434929
102162497	102162520	11	-	26627737	HeLa	viability after 8 days	GACGTTCATCTGGGACAGCATGG	YAP1	ENSG00000137693	-0.7766964988238283	[594]	[154,129,167]	-7	hSpCas9	negative selection	1434930
102229724	102229747	11	-	26627737	HeLa	viability after 8 days	AACGGTTCTGCTGTGAGGGCAGG	YAP1	ENSG00000137693	-1.1028131379389745	[175]	[38,66,3]	-8	hSpCas9	negative selection	1434931
102110992	102111015	11	-	26627737	HeLa	viability after 12 days	GCACGATCTGATGCCCGGCGGGG	YAP1	ENSG00000137693	-0.5493161005993816	[718]	[153,105,357]	-5	hSpCas9	negative selection	1517242
102111003	102111026	11	+	26627737	HeLa	viability after 12 days	ATCAGATCGTGCACGTCCGCGGG	YAP1	ENSG00000137693	-1.6319075333732163	[566]	[113,74,38]	-9	hSpCas9	negative selection	1517243
102111157	102111180	11	-	26627737	HeLa	viability after 12 days	ACGAGGTTACCTGTCGGGAGTGG	YAP1	ENSG00000137693	-0.7999546233965606	[438]	[55,58,200]	-6	hSpCas9	negative selection	1517244
102162497	102162520	11	-	26627737	HeLa	viability after 12 days	GACGTTCATCTGGGACAGCATGG	YAP1	ENSG00000137693	-0.45165542913816403	[594]	[112,268,145]	-4	hSpCas9	negative selection	1517245
102229724	102229747	11	-	26627737	HeLa	viability after 12 days	AACGGTTCTGCTGTGAGGGCAGG	YAP1	ENSG00000137693	-0.9393389096558142	[175]	[6,17,89]	-7	hSpCas9	negative selection	1517246
102110992	102111015	11	-	26627737	HeLa	viability after 15 days	GCACGATCTGATGCCCGGCGGGG	YAP1	ENSG00000137693	-1.538005564426307	[718]	[57,70,179]	-8	hSpCas9	negative selection	1599557
102111003	102111026	11	+	26627737	HeLa	viability after 15 days	ATCAGATCGTGCACGTCCGCGGG	YAP1	ENSG00000137693	-1.6032043764879864	[566]	[90,129,0]	-8	hSpCas9	negative selection	1599558
102111157	102111180	11	-	26627737	HeLa	viability after 15 days	ACGAGGTTACCTGTCGGGAGTGG	YAP1	ENSG00000137693	-0.5830011850882273	[438]	[90,78,193]	-5	hSpCas9	negative selection	1599559
102162497	102162520	11	-	26627737	HeLa	viability after 15 days	GACGTTCATCTGGGACAGCATGG	YAP1	ENSG00000137693	-0.3556114751620618	[594]	[97,270,200]	-3	hSpCas9	negative selection	1599560
102229724	102229747	11	-	26627737	HeLa	viability after 15 days	AACGGTTCTGCTGTGAGGGCAGG	YAP1	ENSG00000137693	-1.0944721745729915	[175]	[46,49,0]	-7	hSpCas9	negative selection	1599561
102110992	102111015	11	-	26627737	HeLa	viability after 18 days	GCACGATCTGATGCCCGGCGGGG	YAP1	ENSG00000137693	-1.5332157860062645	[718]	[36,61,179]	-8	hSpCas9	negative selection	1681872
102111003	102111026	11	+	26627737	HeLa	viability after 18 days	ATCAGATCGTGCACGTCCGCGGG	YAP1	ENSG00000137693	-1.5777817203567914	[566]	[64,105,0]	-8	hSpCas9	negative selection	1681873
102111157	102111180	11	-	26627737	HeLa	viability after 18 days	ACGAGGTTACCTGTCGGGAGTGG	YAP1	ENSG00000137693	-0.5570594554110677	[438]	[59,71,193]	-5	hSpCas9	negative selection	1681874
102162497	102162520	11	-	26627737	HeLa	viability after 18 days	GACGTTCATCTGGGACAGCATGG	YAP1	ENSG00000137693	-0.3441805369659168	[594]	[68,223,200]	-3	hSpCas9	negative selection	1681875
102229724	102229747	11	-	26627737	HeLa	viability after 18 days	AACGGTTCTGCTGTGAGGGCAGG	YAP1	ENSG00000137693	-1.1270314910445272	[175]	[31,38,0]	-7	hSpCas9	negative selection	1681876
102110992	102111015	11	-	26627737	HCT116	viability after 6 days	GCACGATCTGATGCCCGGCGGGG	YAP1	ENSG00000137693	1.150563819489348	[1360]	[532,442]	6	hSpCas9	negative selection	1764187
102111003	102111026	11	+	26627737	HCT116	viability after 6 days	ATCAGATCGTGCACGTCCGCGGG	YAP1	ENSG00000137693	1.7246151370154088	[390]	[255,173]	8	hSpCas9	negative selection	1764188
102111157	102111180	11	-	26627737	HCT116	viability after 6 days	ACGAGGTTACCTGTCGGGAGTGG	YAP1	ENSG00000137693	0.3730847351760723	[850]	[316,93]	2	hSpCas9	negative selection	1764189
102162497	102162520	11	-	26627737	HCT116	viability after 6 days	GACGTTCATCTGGGACAGCATGG	YAP1	ENSG00000137693	1.4034501598740272	[538]	[111,285]	7	hSpCas9	negative selection	1764190
102229724	102229747	11	-	26627737	HCT116	viability after 6 days	AACGGTTCTGCTGTGAGGGCAGG	YAP1	ENSG00000137693	2.241956434010973	[244]	[80,237]	9	hSpCas9	negative selection	1764191
102110992	102111015	11	-	26627737	HCT116	viability after 8 days	GCACGATCTGATGCCCGGCGGGG	YAP1	ENSG00000137693	-0.05999323367879583	[481]	[276,172,313]	0	hSpCas9	negative selection	1846502
102111003	102111026	11	+	26627737	HCT116	viability after 8 days	ATCAGATCGTGCACGTCCGCGGG	YAP1	ENSG00000137693	-0.8043171187495932	[376]	[107,73,173]	-7	hSpCas9	negative selection	1846503
102111157	102111180	11	-	26627737	HCT116	viability after 8 days	ACGAGGTTACCTGTCGGGAGTGG	YAP1	ENSG00000137693	-0.00182085502080237	[339]	[264,132,164]	0	hSpCas9	negative selection	1846504
102162497	102162520	11	-	26627737	HCT116	viability after 8 days	GACGTTCATCTGGGACAGCATGG	YAP1	ENSG00000137693	0.38776908890887807	[220]	[97,145,231]	4	hSpCas9	negative selection	1846505
102229724	102229747	11	-	26627737	HCT116	viability after 8 days	AACGGTTCTGCTGTGAGGGCAGG	YAP1	ENSG00000137693	0.3806213031047705	[79]	[52,53,64]	4	hSpCas9	negative selection	1846506
102110992	102111015	11	-	26627737	HCT116	viability after 9 days	GCACGATCTGATGCCCGGCGGGG	YAP1	ENSG00000137693	-0.39811485136182034	[1360]	[234,307]	-3	hSpCas9	negative selection	1928817
102111003	102111026	11	+	26627737	HCT116	viability after 9 days	ATCAGATCGTGCACGTCCGCGGG	YAP1	ENSG00000137693	0.9586605303681099	[390]	[322,107]	6	hSpCas9	negative selection	1928818
102111157	102111180	11	-	26627737	HCT116	viability after 9 days	ACGAGGTTACCTGTCGGGAGTGG	YAP1	ENSG00000137693	-3.0606761130548925	[850]	[24,28]	-9	hSpCas9	negative selection	1928819
102162497	102162520	11	-	26627737	HCT116	viability after 9 days	GACGTTCATCTGGGACAGCATGG	YAP1	ENSG00000137693	0.25786855969613554	[538]	[299,70]	2	hSpCas9	negative selection	1928820
102229724	102229747	11	-	26627737	HCT116	viability after 9 days	AACGGTTCTGCTGTGAGGGCAGG	YAP1	ENSG00000137693	0.5211421109419131	[244]	[94,92]	4	hSpCas9	negative selection	1928821
102110992	102111015	11	-	26627737	HCT116	viability after 12 days	GCACGATCTGATGCCCGGCGGGG	YAP1	ENSG00000137693	-0.4563208020573204	[481]	[160,104,287]	-5	hSpCas9	negative selection	2011132
102111003	102111026	11	+	26627737	HCT116	viability after 12 days	ATCAGATCGTGCACGTCCGCGGG	YAP1	ENSG00000137693	-0.745531396645468	[376]	[101,120,132]	-7	hSpCas9	negative selection	2011133
102111157	102111180	11	-	26627737	HCT116	viability after 12 days	ACGAGGTTACCTGTCGGGAGTGG	YAP1	ENSG00000137693	-0.6488633577138526	[339]	[123,72,142]	-6	hSpCas9	negative selection	2011134
102162497	102162520	11	-	26627737	HCT116	viability after 12 days	GACGTTCATCTGGGACAGCATGG	YAP1	ENSG00000137693	0.7273563541182668	[220]	[119,183,278]	6	hSpCas9	negative selection	2011135
102229724	102229747	11	-	26627737	HCT116	viability after 12 days	AACGGTTCTGCTGTGAGGGCAGG	YAP1	ENSG00000137693	-0.27172302806160453	[79]	[49,28,23]	-3	hSpCas9	negative selection	2011136
102110992	102111015	11	-	26627737	HCT116	viability after 15 days	GCACGATCTGATGCCCGGCGGGG	YAP1	ENSG00000137693	-0.11015076448572136	[481]	[327,185,263]	-1	hSpCas9	negative selection	2093447
102111003	102111026	11	+	26627737	HCT116	viability after 15 days	ATCAGATCGTGCACGTCCGCGGG	YAP1	ENSG00000137693	-0.8357616199807614	[376]	[112,135,113]	-7	hSpCas9	negative selection	2093448
102111157	102111180	11	-	26627737	HCT116	viability after 15 days	ACGAGGTTACCTGTCGGGAGTGG	YAP1	ENSG00000137693	-0.4238517358634534	[339]	[102,142,184]	-4	hSpCas9	negative selection	2093449
102162497	102162520	11	-	26627737	HCT116	viability after 15 days	GACGTTCATCTGGGACAGCATGG	YAP1	ENSG00000137693	-0.1741192345002207	[220]	[112,67,155]	-2	hSpCas9	negative selection	2093450
102229724	102229747	11	-	26627737	HCT116	viability after 15 days	AACGGTTCTGCTGTGAGGGCAGG	YAP1	ENSG00000137693	-2.0990862000761723	[79]	[32,0,0]	-9	hSpCas9	negative selection	2093451
102110992	102111015	11	-	26627737	HCT116	viability after 18 days	GCACGATCTGATGCCCGGCGGGG	YAP1	ENSG00000137693	0.09666797728936338	[481]	[366,33,365]	0	hSpCas9	negative selection	2175762
102111003	102111026	11	+	26627737	HCT116	viability after 18 days	ATCAGATCGTGCACGTCCGCGGG	YAP1	ENSG00000137693	-0.6757766970928947	[376]	[50,150,138]	-6	hSpCas9	negative selection	2175763
102111157	102111180	11	-	26627737	HCT116	viability after 18 days	ACGAGGTTACCTGTCGGGAGTGG	YAP1	ENSG00000137693	-0.9806115627077667	[339]	[62,124,57]	-7	hSpCas9	negative selection	2175764
102162497	102162520	11	-	26627737	HCT116	viability after 18 days	GACGTTCATCTGGGACAGCATGG	YAP1	ENSG00000137693	0.7627247313245471	[220]	[112,147,289]	6	hSpCas9	negative selection	2175765
102229724	102229747	11	-	26627737	HCT116	viability after 18 days	AACGGTTCTGCTGTGAGGGCAGG	YAP1	ENSG00000137693	0.6147272192721445	[79]	[109,26,41]	5	hSpCas9	negative selection	2175766
102112307	102112330	11	-	25494202	A375	resistance to PLX-4720 (puromycin)	ACTTCTATGCTGAATCAAGTTGG	YAP1	ENSG00000137693	0.22011443726508473	[378,226]	[67,86]	1	dCas9-VP64	positive selection	2409126
102112343	102112366	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	ATGAGTGTTAACATTCCAATAGG	YAP1	ENSG00000137693	0.3048928524103456	[319,694]	[75,205]	1	dCas9-VP64	positive selection	2409127
102112249	102112272	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCTTATTGCGGATATGAACATGG	YAP1	ENSG00000137693	-2.8603062304374003	[230,231]	[6,5]	-9	dCas9-VP64	positive selection	2409128
102202370	102202393	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGGGTTTCACCATGTTAGCCCGG	YAP1	ENSG00000137693	-0.6909980618209312	[118,65]	[15,7]	-4	dCas9-VP64	positive selection	2439248
102194080	102194103	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCGTGAGCCACCGTGCCAAG	YAP1	ENSG00000137693	0.40998119487686246	[103,58]	[28,16]	1	dCas9-VP64	positive selection	2466065
102164185	102164208	11	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAAAAATTAGCTGGGTGTGGAGG	YAP1	ENSG00000137693	-2.5797701712444865	[504,29]	[12,4]	-9	dCas9-VP64	positive selection	2473438
102112307	102112330	11	-	25494202	A375	resistance to PLX-4720 (zeocin)	ACTTCTATGCTGAATCAAGTTGG	YAP1	ENSG00000137693	0.11297401280743513	[129,189]	[33,76]	0	dCas9-VP64	positive selection	2504381
102112343	102112366	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	ATGAGTGTTAACATTCCAATAGG	YAP1	ENSG00000137693	-0.3561180865327338	[321,364]	[117,58]	-4	dCas9-VP64	positive selection	2504382
102112249	102112272	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCTTATTGCGGATATGAACATGG	YAP1	ENSG00000137693	1.6553256368266722	[51,23]	[47,31]	8	dCas9-VP64	positive selection	2504383
102202370	102202393	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGGGTTTCACCATGTTAGCCCGG	YAP1	ENSG00000137693	0.84274483203793	[27,27]	[10,20]	5	dCas9-VP64	positive selection	2534503
102194080	102194103	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCGTGAGCCACCGTGCCAAG	YAP1	ENSG00000137693	0.6377058725861018	[58,96]	[43,34]	5	dCas9-VP64	positive selection	2561320
102164185	102164208	11	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAAAAATTAGCTGGGTGTGGAGG	YAP1	ENSG00000137693	0.3593778947128078	[15,191]	[23,59]	3	dCas9-VP64	positive selection	2568693
102110886	102110909	11	-	27260157	DLD1	viability	AGGCGGCTGCCCTTGGCCCTGGG	YAP1	ENSG00000137693	-1.51664568539282	[]	[]	-8	hSpCas9	negative selection	2577270
102110847	102110870	11	-	27260157	DLD1	viability	CGGCTGCTGCCCGGGATCCATGG	YAP1	ENSG00000137693	-3.47177587786063	[]	[]	-9	hSpCas9	negative selection	2582999
102111025	102111048	11	+	27260157	DLD1	viability	GGACTCGGAGACCGACCTGGAGG	YAP1	ENSG00000137693	-3.52993605640528	[]	[]	-9	hSpCas9	negative selection	2607828
102112601	102112624	11	+	27260157	DLD1	viability	CCTGTTGTATAGTCTCCTGTCGG	YAP1	ENSG00000137693	-0.506682461375725	[]	[]	-4	hSpCas9	negative selection	2609031
102110990	102111013	11	-	27260157	DLD1	viability	ACGATCTGATGCCCGGCGGGGGG	YAP1	ENSG00000137693	-3.37951023060049	[]	[]	-9	hSpCas9	negative selection	2609282
102111002	102111025	11	+	27260157	DLD1	viability	CATCAGATCGTGCACGTCCGCGG	YAP1	ENSG00000137693	-2.39541244493698	[]	[]	-9	hSpCas9	negative selection	2609887
102112529	102112552	11	-	27260157	DLD1	viability	ACTCAAGTTACATCCCGAGTGGG	YAP1	ENSG00000137693	-0.171180749214932	[]	[]	-1	hSpCas9	negative selection	2612642
102111162	102111185	11	-	27260157	DLD1	viability	GGGCAACGAGGTTACCTGTCGGG	YAP1	ENSG00000137693	-4.80850316194877	[]	[]	-9	hSpCas9	negative selection	2614420
102110860	102110883	11	+	27260157	DLD1	viability	GCAGCAGCCGCCGCCTCAACCGG	YAP1	ENSG00000137693	-0.407212289625187	[]	[]	-3	hSpCas9	negative selection	2614601
102112531	102112554	11	+	27260157	DLD1	viability	CACTCGGGATGTAACTTGAGTGG	YAP1	ENSG00000137693	-0.28678221152609	[]	[]	-2	hSpCas9	negative selection	2616111
102111112	102111135	11	-	27260157	DLD1	viability	AGAAGGAGTCGGGCAGCTTCCGG	YAP1	ENSG00000137693	-1.6473478744665	[]	[]	-8	hSpCas9	negative selection	2616303
102110837	102110860	11	+	27260157	DLD1	viability	GAGGCAGAAGCCATGGATCCCGG	YAP1	ENSG00000137693	-3.27240130452938	[]	[]	-9	hSpCas9	negative selection	2616547
102111124	102111147	11	+	27260157	DLD1	viability	CGACTCCTTCTTCAAGCCGCCGG	YAP1	ENSG00000137693	-1.52403891122238	[]	[]	-8	hSpCas9	negative selection	2618564
102111150	102111173	11	-	27260157	DLD1	viability	TACCTGTCGGGAGTGGGATTTGG	YAP1	ENSG00000137693	-2.6603764999417	[]	[]	-9	hSpCas9	negative selection	2621666
102112515	102112538	11	+	27260157	DLD1	viability	TGCAATGTAGTTAGCCCACTCGG	YAP1	ENSG00000137693	-0.295445489396374	[]	[]	-2	hSpCas9	negative selection	2622528
102111140	102111163	11	-	27260157	DLD1	viability	GAGTGGGATTTGGGCTCCGGCGG	YAP1	ENSG00000137693	-2.92052879334531	[]	[]	-9	hSpCas9	negative selection	2622896
102111036	102111059	11	-	27260157	DLD1	viability	GTTGAAGAGCGCCTCCAGGTCGG	YAP1	ENSG00000137693	-2.79483297553878	[]	[]	-9	hSpCas9	negative selection	2641761
102112583	102112606	11	-	27260157	DLD1	viability	ACAGGCCTGCAAATAGGAGAGGG	YAP1	ENSG00000137693	0.142771589642044	[]	[]	3	hSpCas9	negative selection	2643546
102112578	102112601	11	+	27260157	DLD1	viability	CCATTCCCTCTCCTATTTGCAGG	YAP1	ENSG00000137693	-1.23663344794055	[]	[]	-7	hSpCas9	negative selection	2648559
102111122	102111145	11	-	27260157	DLD1	viability	GGCGGCTTGAAGAAGGAGTCGGG	YAP1	ENSG00000137693	-1.76368401426728	[]	[]	-8	hSpCas9	negative selection	2648840
102110886	102110909	11	-	27260157	HT1080	viability	AGGCGGCTGCCCTTGGCCCTGGG	YAP1	ENSG00000137693	0.149580113955221	[]	[]	1	hSpCas9	negative selection	2653400
102110847	102110870	11	-	27260157	HT1080	viability	CGGCTGCTGCCCGGGATCCATGG	YAP1	ENSG00000137693	-0.592394854386196	[]	[]	-7	hSpCas9	negative selection	2659129
102111025	102111048	11	+	27260157	HT1080	viability	GGACTCGGAGACCGACCTGGAGG	YAP1	ENSG00000137693	-0.51418610515872	[]	[]	-7	hSpCas9	negative selection	2683958
102112601	102112624	11	+	27260157	HT1080	viability	CCTGTTGTATAGTCTCCTGTCGG	YAP1	ENSG00000137693	-0.448759373606783	[]	[]	-7	hSpCas9	negative selection	2685161
102110990	102111013	11	-	27260157	HT1080	viability	ACGATCTGATGCCCGGCGGGGGG	YAP1	ENSG00000137693	-0.191301065838687	[]	[]	0	hSpCas9	negative selection	2685412
102111002	102111025	11	+	27260157	HT1080	viability	CATCAGATCGTGCACGTCCGCGG	YAP1	ENSG00000137693	0.0220652387304119	[]	[]	0	hSpCas9	negative selection	2686017
102112529	102112552	11	-	27260157	HT1080	viability	ACTCAAGTTACATCCCGAGTGGG	YAP1	ENSG00000137693	-0.0960989465455367	[]	[]	0	hSpCas9	negative selection	2688772
102111162	102111185	11	-	27260157	HT1080	viability	GGGCAACGAGGTTACCTGTCGGG	YAP1	ENSG00000137693	-0.51161176496168	[]	[]	-7	hSpCas9	negative selection	2690550
102110860	102110883	11	+	27260157	HT1080	viability	GCAGCAGCCGCCGCCTCAACCGG	YAP1	ENSG00000137693	0.232107671992268	[]	[]	2	hSpCas9	negative selection	2690731
102112531	102112554	11	+	27260157	HT1080	viability	CACTCGGGATGTAACTTGAGTGG	YAP1	ENSG00000137693	-0.538242435069749	[]	[]	-7	hSpCas9	negative selection	2692241
102111112	102111135	11	-	27260157	HT1080	viability	AGAAGGAGTCGGGCAGCTTCCGG	YAP1	ENSG00000137693	1.21997944177477	[]	[]	8	hSpCas9	negative selection	2692433
102110837	102110860	11	+	27260157	HT1080	viability	GAGGCAGAAGCCATGGATCCCGG	YAP1	ENSG00000137693	0.456866614039098	[]	[]	4	hSpCas9	negative selection	2692677
102111124	102111147	11	+	27260157	HT1080	viability	CGACTCCTTCTTCAAGCCGCCGG	YAP1	ENSG00000137693	-0.0175716868110714	[]	[]	0	hSpCas9	negative selection	2694694
102111150	102111173	11	-	27260157	HT1080	viability	TACCTGTCGGGAGTGGGATTTGG	YAP1	ENSG00000137693	-0.268208179224085	[]	[]	0	hSpCas9	negative selection	2697796
102112515	102112538	11	+	27260157	HT1080	viability	TGCAATGTAGTTAGCCCACTCGG	YAP1	ENSG00000137693	0.0033124817358146	[]	[]	0	hSpCas9	negative selection	2698658
102111140	102111163	11	-	27260157	HT1080	viability	GAGTGGGATTTGGGCTCCGGCGG	YAP1	ENSG00000137693	-1.56014996069347	[]	[]	-9	hSpCas9	negative selection	2699026
102111036	102111059	11	-	27260157	HT1080	viability	GTTGAAGAGCGCCTCCAGGTCGG	YAP1	ENSG00000137693	0.370731125067036	[]	[]	3	hSpCas9	negative selection	2717891
102112583	102112606	11	-	27260157	HT1080	viability	ACAGGCCTGCAAATAGGAGAGGG	YAP1	ENSG00000137693	0.274758289307802	[]	[]	2	hSpCas9	negative selection	2719676
102112578	102112601	11	+	27260157	HT1080	viability	CCATTCCCTCTCCTATTTGCAGG	YAP1	ENSG00000137693	-1.23987375052296	[]	[]	-9	hSpCas9	negative selection	2724689
102111122	102111145	11	-	27260157	HT1080	viability	GGCGGCTTGAAGAAGGAGTCGGG	YAP1	ENSG00000137693	0.323595605298401	[]	[]	3	hSpCas9	negative selection	2724970
102110886	102110909	11	-	27260157	MKN45	viability	AGGCGGCTGCCCTTGGCCCTGGG	YAP1	ENSG00000137693	0.846627381863418	[]	[]	8	hSpCas9	negative selection	2729530
102110847	102110870	11	-	27260157	MKN45	viability	CGGCTGCTGCCCGGGATCCATGG	YAP1	ENSG00000137693	0.612842483894771	[]	[]	7	hSpCas9	negative selection	2735259
102111025	102111048	11	+	27260157	MKN45	viability	GGACTCGGAGACCGACCTGGAGG	YAP1	ENSG00000137693	-0.118041949426746	[]	[]	0	hSpCas9	negative selection	2760088
102112601	102112624	11	+	27260157	MKN45	viability	CCTGTTGTATAGTCTCCTGTCGG	YAP1	ENSG00000137693	0.648294375416092	[]	[]	7	hSpCas9	negative selection	2761291
102110990	102111013	11	-	27260157	MKN45	viability	ACGATCTGATGCCCGGCGGGGGG	YAP1	ENSG00000137693	0.552004257961856	[]	[]	7	hSpCas9	negative selection	2761542
102111002	102111025	11	+	27260157	MKN45	viability	CATCAGATCGTGCACGTCCGCGG	YAP1	ENSG00000137693	1.41277255532295	[]	[]	9	hSpCas9	negative selection	2762147
102112529	102112552	11	-	27260157	MKN45	viability	ACTCAAGTTACATCCCGAGTGGG	YAP1	ENSG00000137693	1.90409112917695	[]	[]	9	hSpCas9	negative selection	2764902
102111162	102111185	11	-	27260157	MKN45	viability	GGGCAACGAGGTTACCTGTCGGG	YAP1	ENSG00000137693	0.798275793568033	[]	[]	7	hSpCas9	negative selection	2766680
102110860	102110883	11	+	27260157	MKN45	viability	GCAGCAGCCGCCGCCTCAACCGG	YAP1	ENSG00000137693	1.88219125289229	[]	[]	9	hSpCas9	negative selection	2766861
102112531	102112554	11	+	27260157	MKN45	viability	CACTCGGGATGTAACTTGAGTGG	YAP1	ENSG00000137693	-0.360062662277914	[]	[]	-1	hSpCas9	negative selection	2768371
102111112	102111135	11	-	27260157	MKN45	viability	AGAAGGAGTCGGGCAGCTTCCGG	YAP1	ENSG00000137693	1.19401147950072	[]	[]	9	hSpCas9	negative selection	2768563
102110837	102110860	11	+	27260157	MKN45	viability	GAGGCAGAAGCCATGGATCCCGG	YAP1	ENSG00000137693	1.16005024116562	[]	[]	8	hSpCas9	negative selection	2768807
102111124	102111147	11	+	27260157	MKN45	viability	CGACTCCTTCTTCAAGCCGCCGG	YAP1	ENSG00000137693	1.04304326215105	[]	[]	8	hSpCas9	negative selection	2770824
102111150	102111173	11	-	27260157	MKN45	viability	TACCTGTCGGGAGTGGGATTTGG	YAP1	ENSG00000137693	-0.507509224869473	[]	[]	-6	hSpCas9	negative selection	2773926
102112515	102112538	11	+	27260157	MKN45	viability	TGCAATGTAGTTAGCCCACTCGG	YAP1	ENSG00000137693	0.0854912048840263	[]	[]	0	hSpCas9	negative selection	2774788
102111140	102111163	11	-	27260157	MKN45	viability	GAGTGGGATTTGGGCTCCGGCGG	YAP1	ENSG00000137693	0.534932783449489	[]	[]	6	hSpCas9	negative selection	2775156
102111036	102111059	11	-	27260157	MKN45	viability	GTTGAAGAGCGCCTCCAGGTCGG	YAP1	ENSG00000137693	1.20005393677635	[]	[]	9	hSpCas9	negative selection	2794021
102112583	102112606	11	-	27260157	MKN45	viability	ACAGGCCTGCAAATAGGAGAGGG	YAP1	ENSG00000137693	1.10416512849401	[]	[]	8	hSpCas9	negative selection	2795806
102112578	102112601	11	+	27260157	MKN45	viability	CCATTCCCTCTCCTATTTGCAGG	YAP1	ENSG00000137693	-0.450778114495711	[]	[]	-6	hSpCas9	negative selection	2800819
102111122	102111145	11	-	27260157	MKN45	viability	GGCGGCTTGAAGAAGGAGTCGGG	YAP1	ENSG00000137693	1.12532422782395	[]	[]	8	hSpCas9	negative selection	2801100
102110886	102110909	11	-	27260157	RKO	viability	AGGCGGCTGCCCTTGGCCCTGGG	YAP1	ENSG00000137693	-0.108954219193898	[]	[]	0	hSpCas9	negative selection	2805660
102110847	102110870	11	-	27260157	RKO	viability	CGGCTGCTGCCCGGGATCCATGG	YAP1	ENSG00000137693	-2.07390654946355	[]	[]	-9	hSpCas9	negative selection	2811389
102111025	102111048	11	+	27260157	RKO	viability	GGACTCGGAGACCGACCTGGAGG	YAP1	ENSG00000137693	-1.89714285732321	[]	[]	-9	hSpCas9	negative selection	2836218
102112601	102112624	11	+	27260157	RKO	viability	CCTGTTGTATAGTCTCCTGTCGG	YAP1	ENSG00000137693	-1.03170036744915	[]	[]	-8	hSpCas9	negative selection	2837421
102110990	102111013	11	-	27260157	RKO	viability	ACGATCTGATGCCCGGCGGGGGG	YAP1	ENSG00000137693	-0.923891130732838	[]	[]	-8	hSpCas9	negative selection	2837672
102111002	102111025	11	+	27260157	RKO	viability	CATCAGATCGTGCACGTCCGCGG	YAP1	ENSG00000137693	-0.966027464468	[]	[]	-8	hSpCas9	negative selection	2838277
102112529	102112552	11	-	27260157	RKO	viability	ACTCAAGTTACATCCCGAGTGGG	YAP1	ENSG00000137693	0.369192361263859	[]	[]	2	hSpCas9	negative selection	2841032
102111162	102111185	11	-	27260157	RKO	viability	GGGCAACGAGGTTACCTGTCGGG	YAP1	ENSG00000137693	-1.44530169590159	[]	[]	-8	hSpCas9	negative selection	2842810
102110860	102110883	11	+	27260157	RKO	viability	GCAGCAGCCGCCGCCTCAACCGG	YAP1	ENSG00000137693	-1.59601705732975	[]	[]	-9	hSpCas9	negative selection	2842991
102112531	102112554	11	+	27260157	RKO	viability	CACTCGGGATGTAACTTGAGTGG	YAP1	ENSG00000137693	0.283195276824246	[]	[]	1	hSpCas9	negative selection	2844501
102111112	102111135	11	-	27260157	RKO	viability	AGAAGGAGTCGGGCAGCTTCCGG	YAP1	ENSG00000137693	-0.320723981699361	[]	[]	-6	hSpCas9	negative selection	2844693
102110837	102110860	11	+	27260157	RKO	viability	GAGGCAGAAGCCATGGATCCCGG	YAP1	ENSG00000137693	-0.150167257724834	[]	[]	0	hSpCas9	negative selection	2844937
102111124	102111147	11	+	27260157	RKO	viability	CGACTCCTTCTTCAAGCCGCCGG	YAP1	ENSG00000137693	-0.708128876435658	[]	[]	-7	hSpCas9	negative selection	2846954
102111150	102111173	11	-	27260157	RKO	viability	TACCTGTCGGGAGTGGGATTTGG	YAP1	ENSG00000137693	-1.33461895477737	[]	[]	-8	hSpCas9	negative selection	2850056
102112515	102112538	11	+	27260157	RKO	viability	TGCAATGTAGTTAGCCCACTCGG	YAP1	ENSG00000137693	0.585961028155851	[]	[]	3	hSpCas9	negative selection	2850918
102111140	102111163	11	-	27260157	RKO	viability	GAGTGGGATTTGGGCTCCGGCGG	YAP1	ENSG00000137693	-2.42691280639781	[]	[]	-9	hSpCas9	negative selection	2851286
102111036	102111059	11	-	27260157	RKO	viability	GTTGAAGAGCGCCTCCAGGTCGG	YAP1	ENSG00000137693	-1.05539318236907	[]	[]	-8	hSpCas9	negative selection	2870151
102112583	102112606	11	-	27260157	RKO	viability	ACAGGCCTGCAAATAGGAGAGGG	YAP1	ENSG00000137693	0.444286611170373	[]	[]	2	hSpCas9	negative selection	2871936
102112578	102112601	11	+	27260157	RKO	viability	CCATTCCCTCTCCTATTTGCAGG	YAP1	ENSG00000137693	-1.45716064102021	[]	[]	-8	hSpCas9	negative selection	2876949
102111122	102111145	11	-	27260157	RKO	viability	GGCGGCTTGAAGAAGGAGTCGGG	YAP1	ENSG00000137693	-0.326606235511725	[]	[]	-6	hSpCas9	negative selection	2877230
102110886	102110909	11	-	27260157	SF268	viability	AGGCGGCTGCCCTTGGCCCTGGG	YAP1	ENSG00000137693	-1.61988464046354	[]	[]	-8	hSpCas9	negative selection	2881790
102110847	102110870	11	-	27260157	SF268	viability	CGGCTGCTGCCCGGGATCCATGG	YAP1	ENSG00000137693	-4.1249642909253	[]	[]	-9	hSpCas9	negative selection	2887519
102111025	102111048	11	+	27260157	SF268	viability	GGACTCGGAGACCGACCTGGAGG	YAP1	ENSG00000137693	-4.69572081909505	[]	[]	-9	hSpCas9	negative selection	2912348
102112601	102112624	11	+	27260157	SF268	viability	CCTGTTGTATAGTCTCCTGTCGG	YAP1	ENSG00000137693	-4.14768414919545	[]	[]	-9	hSpCas9	negative selection	2913551
102110990	102111013	11	-	27260157	SF268	viability	ACGATCTGATGCCCGGCGGGGGG	YAP1	ENSG00000137693	-3.48913420283765	[]	[]	-9	hSpCas9	negative selection	2913802
102111002	102111025	11	+	27260157	SF268	viability	CATCAGATCGTGCACGTCCGCGG	YAP1	ENSG00000137693	-2.760159280132	[]	[]	-9	hSpCas9	negative selection	2914407
102112529	102112552	11	-	27260157	SF268	viability	ACTCAAGTTACATCCCGAGTGGG	YAP1	ENSG00000137693	-5.3711202919312	[]	[]	-9	hSpCas9	negative selection	2917162
102111162	102111185	11	-	27260157	SF268	viability	GGGCAACGAGGTTACCTGTCGGG	YAP1	ENSG00000137693	-5.14544666500929	[]	[]	-9	hSpCas9	negative selection	2918940
102110860	102110883	11	+	27260157	SF268	viability	GCAGCAGCCGCCGCCTCAACCGG	YAP1	ENSG00000137693	-2.76315714972108	[]	[]	-9	hSpCas9	negative selection	2919121
102112531	102112554	11	+	27260157	SF268	viability	CACTCGGGATGTAACTTGAGTGG	YAP1	ENSG00000137693	-2.19953188588379	[]	[]	-9	hSpCas9	negative selection	2920631
102111112	102111135	11	-	27260157	SF268	viability	AGAAGGAGTCGGGCAGCTTCCGG	YAP1	ENSG00000137693	-3.01154301651903	[]	[]	-9	hSpCas9	negative selection	2920823
102110837	102110860	11	+	27260157	SF268	viability	GAGGCAGAAGCCATGGATCCCGG	YAP1	ENSG00000137693	-2.60290645666239	[]	[]	-9	hSpCas9	negative selection	2921067
102111124	102111147	11	+	27260157	SF268	viability	CGACTCCTTCTTCAAGCCGCCGG	YAP1	ENSG00000137693	-2.64799515175894	[]	[]	-9	hSpCas9	negative selection	2923084
102111150	102111173	11	-	27260157	SF268	viability	TACCTGTCGGGAGTGGGATTTGG	YAP1	ENSG00000137693	-3.15844989075983	[]	[]	-9	hSpCas9	negative selection	2926186
102112515	102112538	11	+	27260157	SF268	viability	TGCAATGTAGTTAGCCCACTCGG	YAP1	ENSG00000137693	-2.23318622218898	[]	[]	-9	hSpCas9	negative selection	2927048
102111140	102111163	11	-	27260157	SF268	viability	GAGTGGGATTTGGGCTCCGGCGG	YAP1	ENSG00000137693	-4.34754645662835	[]	[]	-9	hSpCas9	negative selection	2927416
102111036	102111059	11	-	27260157	SF268	viability	GTTGAAGAGCGCCTCCAGGTCGG	YAP1	ENSG00000137693	-3.4117733807856	[]	[]	-9	hSpCas9	negative selection	2946281
102112583	102112606	11	-	27260157	SF268	viability	ACAGGCCTGCAAATAGGAGAGGG	YAP1	ENSG00000137693	-2.25056880506465	[]	[]	-9	hSpCas9	negative selection	2948066
102112578	102112601	11	+	27260157	SF268	viability	CCATTCCCTCTCCTATTTGCAGG	YAP1	ENSG00000137693	-4.10291433028599	[]	[]	-9	hSpCas9	negative selection	2953079
102111122	102111145	11	-	27260157	SF268	viability	GGCGGCTTGAAGAAGGAGTCGGG	YAP1	ENSG00000137693	-3.84230967703185	[]	[]	-9	hSpCas9	negative selection	2953360
102162459	102162482	11	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	-1.4211127871772968	[3,3]	[1,0]	-9	hSpCas9	positive selection	3032920
102186012	102186035	11	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATTATAGGTCCTCTTCCTGATGG	YAP1	ENSG00000137693	0.11980855312366306	[4,4]	[4,4]	2	hSpCas9	positive selection	3032921
102186093	102186116	11	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTTGGGTCTAGCCAAGAGGTGG	YAP1	ENSG00000137693	-0.6786081769268713	[2,2]	[1,0]	-8	hSpCas9	positive selection	3032922
102186122	102186145	11	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GATGAACCTTTACCAAAACGAGG	YAP1	ENSG00000137693	-0.6976548537019099	[3,3]	[2,0]	-8	hSpCas9	positive selection	3032923
102162459	102162482	11	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	-0.45779846480207653	[3,3]	[3,0]	-6	hSpCas9	positive selection	3100778
102186012	102186035	11	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATTATAGGTCCTCTTCCTGATGG	YAP1	ENSG00000137693	0.40434201934650643	[4,4]	[5,3]	7	hSpCas9	positive selection	3100779
102186093	102186116	11	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTTGGGTCTAGCCAAGAGGTGG	YAP1	ENSG00000137693	0.07263839937376293	[2,2]	[1,2]	1	hSpCas9	positive selection	3100780
102186122	102186145	11	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GATGAACCTTTACCAAAACGAGG	YAP1	ENSG00000137693	-0.09487544070922943	[3,3]	[2,1]	-1	hSpCas9	positive selection	3100781
102114354	102114377		+	24336571	A375	resistance to PLX after 7 days	GAGATGGCAAAGACATCTTCTGG	YAP1	ENSG00000137693	-0.09796838379212014	[5,4]	[4,4]	-3	hSpCas9	positive selection	3156096
102114138	102114161		+	24336571	A375	resistance to PLX after 7 days	TAATAGGCCAGTACTGATGCAGG	YAP1	ENSG00000137693	-0.3016155659404165	[46,53]	[42,37]	-8	hSpCas9	positive selection	3156097
102162507	102162530		-	24336571	A375	resistance to PLX after 7 days	TGGGGGCTGTGACGTTCATCTGG	YAP1	ENSG00000137693	-0.016123023119326785	[79,69]	[67,78]	0	hSpCas9	positive selection	3156098
102114354	102114377		+	24336571	A375	resistance to PLX after 14 days	GAGATGGCAAAGACATCTTCTGG	YAP1	ENSG00000137693	-0.17776270306319097	[6,6]	[2,2]	-2	hSpCas9	positive selection	3213889
102114138	102114161		+	24336571	A375	resistance to PLX after 14 days	TAATAGGCCAGTACTGATGCAGG	YAP1	ENSG00000137693	-1.2640067181965635	[41,54]	[7,10]	-9	hSpCas9	positive selection	3213890
102162507	102162530		-	24336571	A375	resistance to PLX after 14 days	TGGGGGCTGTGACGTTCATCTGG	YAP1	ENSG00000137693	0.5834344491573868	[71,65]	[48,46]	5	hSpCas9	positive selection	3213891
102114354	102114377		+	24336571	A375	viability after 7 days	GAGATGGCAAAGACATCTTCTGG	YAP1	ENSG00000137693	-0.40987773264115757	[7]	[5,4]	-5	hSpCas9	negative selection	3271682
102114138	102114161		+	24336571	A375	viability after 7 days	TAATAGGCCAGTACTGATGCAGG	YAP1	ENSG00000137693	-0.2043128195894348	[60]	[46,53]	-3	hSpCas9	negative selection	3271683
102162507	102162530		-	24336571	A375	viability after 7 days	TGGGGGCTGTGACGTTCATCTGG	YAP1	ENSG00000137693	0.7473072429652685	[46]	[79,69]	9	hSpCas9	negative selection	3271684
102114354	102114377		+	24336571	A375	viability after 14 days	GAGATGGCAAAGACATCTTCTGG	YAP1	ENSG00000137693	-0.020847078412437492	[7]	[6,6]	0	hSpCas9	negative selection	3329475
102114138	102114161		+	24336571	A375	viability after 14 days	TAATAGGCCAGTACTGATGCAGG	YAP1	ENSG00000137693	-0.23089678647673062	[60]	[41,54]	-3	hSpCas9	negative selection	3329476
102162507	102162530		-	24336571	A375	viability after 14 days	TGGGGGCTGTGACGTTCATCTGG	YAP1	ENSG00000137693	0.6430737218051061	[46]	[71,65]	7	hSpCas9	negative selection	3329477
102186011	102186034	11	+	27383988	293T	resistance to West Nile virus (flavivirus)	ATTATAGGTCCTCTTCCTGATGG	YAP1	ENSG00000137693	-0.35000410230377543	[194,194]	[0,0]	-2	hSpCas9	positive selection	3401758
102205900	102205923	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	GAGCACTCTGACTGATTCTCTGG	YAP1	ENSG00000137693	-0.2184072195205627	[177,177]	[0,0]	-1	hSpCas9	positive selection	3401759
102162458	102162481	11	+	27383988	293T	resistance to West Nile virus (flavivirus)	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	0.9719239925835867	[77,77]	[0,0]	4	hSpCas9	positive selection	3401760
102162458	102162481	11	+	26780180	HT29	viability (Avana library 4 designs)	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	4.59729405805473	[]	[]	9	hSpCas9	negative selection	3472206
102186011	102186034	11	+	26780180	HT29	viability (Avana library 4 designs)	ATTATAGGTCCTCTTCCTGATGG	YAP1	ENSG00000137693	2.51421108718579	[]	[]	8	hSpCas9	negative selection	3472207
102186093	102186116	11	-	26780180	HT29	viability (Avana library 4 designs)	CCTTGGGTCTAGCCAAGAGGTGG	YAP1	ENSG00000137693	3.08718493165028	[]	[]	8	hSpCas9	negative selection	3472208
102186122	102186145	11	-	26780180	HT29	viability (Avana library 4 designs)	GATGAACCTTTACCAAAACGAGG	YAP1	ENSG00000137693	1.7856537506911	[]	[]	6	hSpCas9	negative selection	3472209
102186122	102186145	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	GATGAACCTTTACCAAAACGAGG	YAP1	ENSG00000137693	0.614333331393921	[]	[]	0	hSpCas9	negative selection	3579386
102186011	102186034	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATTATAGGTCCTCTTCCTGATGG	YAP1	ENSG00000137693	-4.50734253027712	[]	[]	-5	hSpCas9	negative selection	3579387
102162458	102162481	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	-2.01141086463292	[]	[]	-2	hSpCas9	negative selection	3579388
102186093	102186116	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCTTGGGTCTAGCCAAGAGGTGG	YAP1	ENSG00000137693	-4.27805832802212	[]	[]	-5	hSpCas9	negative selection	3579389
102186038	102186061	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	GAACAAGCCATGACTCAGGATGG	YAP1	ENSG00000137693	-0.137984109049636	[]	[]	0	hSpCas9	negative selection	3579390
102186121	102186144	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATGAACCTTTACCAAAACGAGGG	YAP1	ENSG00000137693	-5.47445186011477	[]	[]	-5	hSpCas9	negative selection	3579391
102186122	102186145	11	-	26780180	A375	viability (Avana lentiGuide)	GATGAACCTTTACCAAAACGAGG	YAP1	ENSG00000137693	1.30383320089469	[]	[]	1	hSpCas9	negative selection	3688045
102186011	102186034	11	+	26780180	A375	viability (Avana lentiGuide)	ATTATAGGTCCTCTTCCTGATGG	YAP1	ENSG00000137693	0.81949769195741	[]	[]	1	hSpCas9	negative selection	3688046
102162458	102162481	11	+	26780180	A375	viability (Avana lentiGuide)	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	-1.26312678662403	[]	[]	-2	hSpCas9	negative selection	3688047
102186093	102186116	11	-	26780180	A375	viability (Avana lentiGuide)	CCTTGGGTCTAGCCAAGAGGTGG	YAP1	ENSG00000137693	2.71524395533851	[]	[]	3	hSpCas9	negative selection	3688048
102186038	102186061	11	+	26780180	A375	viability (Avana lentiGuide)	GAACAAGCCATGACTCAGGATGG	YAP1	ENSG00000137693	0.512869213894155	[]	[]	0	hSpCas9	negative selection	3688049
102186121	102186144	11	-	26780180	A375	viability (Avana lentiGuide)	ATGAACCTTTACCAAAACGAGGG	YAP1	ENSG00000137693	-2.41359897214678	[]	[]	-4	hSpCas9	negative selection	3688050
102186122	102186145	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATGAACCTTTACCAAAACGAGG	YAP1	ENSG00000137693	-0.15715841351879434	[5]	[4,4]	-3	hSpCas9	positive selection	3796652
102186011	102186034	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATTATAGGTCCTCTTCCTGATGG	YAP1	ENSG00000137693	-0.4959930716953826	[8]	[6,3]	-6	hSpCas9	positive selection	3796653
102162458	102162481	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	-0.31196843145515163	[5]	[4,3]	-5	hSpCas9	positive selection	3796654
102186093	102186116	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTTGGGTCTAGCCAAGAGGTGG	YAP1	ENSG00000137693	-0.18600508960616194	[4]	[4,2]	-3	hSpCas9	positive selection	3796655
102186038	102186061	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAACAAGCCATGACTCAGGATGG	YAP1	ENSG00000137693	-0.08477855390354146	[5]	[5,5]	-1	hSpCas9	positive selection	3796656
102186121	102186144	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATGAACCTTTACCAAAACGAGGG	YAP1	ENSG00000137693	-0.7847408052391561	[5]	[3,2]	-8	hSpCas9	positive selection	3796657
102186122	102186145	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATGAACCTTTACCAAAACGAGG	YAP1	ENSG00000137693	0.02367201174778316	[4]	[2,4]	0	hSpCas9	positive selection	3905259
102186011	102186034	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATTATAGGTCCTCTTCCTGATGG	YAP1	ENSG00000137693	-0.10956390890194512	[6]	[5,4]	-1	hSpCas9	positive selection	3905260
102162458	102162481	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	-0.34992076639370345	[6]	[2,4]	-4	hSpCas9	positive selection	3905261
102186093	102186116	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTTGGGTCTAGCCAAGAGGTGG	YAP1	ENSG00000137693	-0.3033438817722471	[4]	[4,0]	-4	hSpCas9	positive selection	3905262
102186038	102186061	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAACAAGCCATGACTCAGGATGG	YAP1	ENSG00000137693	0.19308530499274942	[6]	[6,5]	5	hSpCas9	positive selection	3905263
102186121	102186144	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATGAACCTTTACCAAAACGAGGG	YAP1	ENSG00000137693	-0.516090705589244	[4]	[0,4]	-6	hSpCas9	positive selection	3905264
102162458	102162481	11	+	26780180	A375	viability	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	0.944205709833035	[]	[]	4	hSpCas9	negative selection	4013329
102186011	102186034	11	+	26780180	A375	viability	ATTATAGGTCCTCTTCCTGATGG	YAP1	ENSG00000137693	1.49856401669396	[]	[]	8	hSpCas9	negative selection	4013330
102186110	102186133	11	+	26780180	A375	viability	CCAAGGCTTGACCCTCGTTTTGG	YAP1	ENSG00000137693	0.800153060597433	[]	[]	3	hSpCas9	negative selection	4013331
102205900	102205923	11	-	26780180	A375	viability	GAGCACTCTGACTGATTCTCTGG	YAP1	ENSG00000137693	1.14806112187982	[]	[]	6	hSpCas9	negative selection	4013332
102205993	102206016	11	-	26780180	A375	viability	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	1.06188893623546	[]	[]	5	hSpCas9	negative selection	4013333
102162507	102162530	11	-	26780180	A375	viability	TGGGGGCTGTGACGTTCATCTGG	YAP1	ENSG00000137693	1.28872762005709	[]	[]	7	hSpCas9	negative selection	4013334
102162458	102162481	11	+	26780180	HT29	viability (GeCKOv2 library)	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	2.44167657125807	[]	[]	9	hSpCas9	negative selection	4121295
102186011	102186034	11	+	26780180	HT29	viability (GeCKOv2 library)	ATTATAGGTCCTCTTCCTGATGG	YAP1	ENSG00000137693	1.91937326274949	[]	[]	9	hSpCas9	negative selection	4121296
102186110	102186133	11	+	26780180	HT29	viability (GeCKOv2 library)	CCAAGGCTTGACCCTCGTTTTGG	YAP1	ENSG00000137693	0.06238028376449	[]	[]	0	hSpCas9	negative selection	4121297
102205900	102205923	11	-	26780180	HT29	viability (GeCKOv2 library)	GAGCACTCTGACTGATTCTCTGG	YAP1	ENSG00000137693	1.57733665973194	[]	[]	8	hSpCas9	negative selection	4121298
102205993	102206016	11	-	26780180	HT29	viability (GeCKOv2 library)	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	1.50670289502964	[]	[]	7	hSpCas9	negative selection	4121299
102162507	102162530	11	-	26780180	HT29	viability (GeCKOv2 library)	TGGGGGCTGTGACGTTCATCTGG	YAP1	ENSG00000137693	1.23967750930676	[]	[]	6	hSpCas9	negative selection	4121300
102114354	102114377	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAGATGGCAAAGACATCTTCTGG	YAP1	ENSG00000137693	-0.12686022738480335	[2]	[1,1]	-3	hSpCas9	positive selection	4182954
102114138	102114161	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TAATAGGCCAGTACTGATGCAGG	YAP1	ENSG00000137693	-0.043062690286016614	[5]	[3,3]	-1	hSpCas9	positive selection	4182955
102162507	102162530	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGGGGGCTGTGACGTTCATCTGG	YAP1	ENSG00000137693	0.3495475103684883	[5]	[4,5]	8	hSpCas9	positive selection	4182956
102114354	102114377	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAGATGGCAAAGACATCTTCTGG	YAP1	ENSG00000137693	0.07214390827084173	[3]	[0,1,4,0]	0	hSpCas9	positive selection	4246976
102114138	102114161	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TAATAGGCCAGTACTGATGCAGG	YAP1	ENSG00000137693	1.0390306545412178	[4]	[4,2,5,4]	7	hSpCas9	positive selection	4246977
102162507	102162530	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGGGGGCTGTGACGTTCATCTGG	YAP1	ENSG00000137693	1.3087476119541435	[4]	[5,4,6,4]	9	hSpCas9	positive selection	4246978
102186110	102186133	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCAAGGCTTGACCCTCGTTTTGG	YAP1	ENSG00000137693	0.38096209005199794	[3]	[3,3]	7	hSpCas9	positive selection	4308248
102162507	102162530	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGGGGGCTGTGACGTTCATCTGG	YAP1	ENSG00000137693	0.03400228200109526	[3]	[3,2]	0	hSpCas9	positive selection	4308249
102205993	102206016	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	-0.2547797092963935	[3]	[2,1]	-5	hSpCas9	positive selection	4308250
102186011	102186034	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATTATAGGTCCTCTTCCTGATGG	YAP1	ENSG00000137693	-0.16230698409589192	[3]	[3,1]	-3	hSpCas9	positive selection	4372495
102205900	102205923	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAGCACTCTGACTGATTCTCTGG	YAP1	ENSG00000137693	-0.17532969990181416	[3]	[2,1]	-4	hSpCas9	positive selection	4372496
102162458	102162481	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	0.06918705384022084	[2]	[2,1]	1	hSpCas9	positive selection	4372497
102111004	102111026	11	+	27760321	OCIAML3	viability	TCAGATCGTGCACGTCCGCGGG	YAP1	ENSG00000137693	0.07811088054744508	[796,659]	[514,707]	0	hSpCas9	negative selection	4454734
102162535	102162557	11	-	27760321	OCIAML3	viability	TCATATTCTGCTGCACTGGTGG	YAP1	ENSG00000137693	0.12585566465756493	[668,572]	[513,546]	1	hSpCas9	negative selection	4454735
102186122	102186144	11	-	27760321	OCIAML3	viability	ATGAACCTTTACCAAAACGAGG	YAP1	ENSG00000137693	0.24405225855120438	[138,100]	[70,160]	3	hSpCas9	negative selection	4454736
102205893	102205915	11	-	27760321	OCIAML3	viability	TGACTGATTCTCTGGTTCATGG	YAP1	ENSG00000137693	0.42627297518172413	[530,445]	[434,610]	5	hSpCas9	negative selection	4454737
102205956	102205978	11	+	27760321	OCIAML3	viability	GCCCACAGGGAGGCGTCATGGG	YAP1	ENSG00000137693	-0.10025475082940505	[791,617]	[433,610]	-1	hSpCas9	negative selection	4454738
102223629	102223651	11	-	27760321	OCIAML3	viability	GTTGGTAACTGGCTACGCAGGG	YAP1	ENSG00000137693	-0.03827463965188871	[539,454]	[383,368]	0	hSpCas9	negative selection	4454739
102111004	102111026	11	+	27760321	OCIAML2	viability	TCAGATCGTGCACGTCCGCGGG	YAP1	ENSG00000137693	0.1811059180512763	[796,659]	[678,646]	2	hSpCas9	negative selection	4538197
102162535	102162557	11	-	27760321	OCIAML2	viability	TCATATTCTGCTGCACTGGTGG	YAP1	ENSG00000137693	-0.11883519337238851	[668,572]	[427,504]	-1	hSpCas9	negative selection	4538198
102186122	102186144	11	-	27760321	OCIAML2	viability	ATGAACCTTTACCAAAACGAGG	YAP1	ENSG00000137693	0.4434493952641396	[138,100]	[128,132]	6	hSpCas9	negative selection	4538199
102205893	102205915	11	-	27760321	OCIAML2	viability	TGACTGATTCTCTGGTTCATGG	YAP1	ENSG00000137693	1.1091117320219843	[530,445]	[679,1071]	9	hSpCas9	negative selection	4538200
102205956	102205978	11	+	27760321	OCIAML2	viability	GCCCACAGGGAGGCGTCATGGG	YAP1	ENSG00000137693	-0.018656544842913347	[791,617]	[455,694]	0	hSpCas9	negative selection	4538201
102223629	102223651	11	-	27760321	OCIAML2	viability	GTTGGTAACTGGCTACGCAGGG	YAP1	ENSG00000137693	0.4036911308234508	[539,454]	[447,638]	5	hSpCas9	negative selection	4538202
102111004	102111026	11	+	27760321	MV411	viability	TCAGATCGTGCACGTCCGCGGG	YAP1	ENSG00000137693	0.4701487003717354	[796,659]	[891,318]	3	hSpCas9	negative selection	4621660
102162535	102162557	11	-	27760321	MV411	viability	TCATATTCTGCTGCACTGGTGG	YAP1	ENSG00000137693	0.20085987582908515	[668,572]	[196,878]	1	hSpCas9	negative selection	4621661
102186122	102186144	11	-	27760321	MV411	viability	ATGAACCTTTACCAAAACGAGG	YAP1	ENSG00000137693	1.078185598321133	[138,100]	[131,215]	7	hSpCas9	negative selection	4621662
102205893	102205915	11	-	27760321	MV411	viability	TGACTGATTCTCTGGTTCATGG	YAP1	ENSG00000137693	0.6158607936758039	[530,445]	[376,664]	4	hSpCas9	negative selection	4621663
102205956	102205978	11	+	27760321	MV411	viability	GCCCACAGGGAGGCGTCATGGG	YAP1	ENSG00000137693	0.8678587816468304	[791,617]	[1096,461]	6	hSpCas9	negative selection	4621664
102223629	102223651	11	-	27760321	MV411	viability	GTTGGTAACTGGCTACGCAGGG	YAP1	ENSG00000137693	1.4486588052383784	[539,454]	[855,947]	9	hSpCas9	negative selection	4621665
102111004	102111026	11	+	27760321	HL60	viability	TCAGATCGTGCACGTCCGCGGG	YAP1	ENSG00000137693	0.5677803659118265	[796,659]	[750,1012]	6	hSpCas9	negative selection	4705123
102162535	102162557	11	-	27760321	HL60	viability	TCATATTCTGCTGCACTGGTGG	YAP1	ENSG00000137693	-0.09870594827446344	[668,572]	[431,514]	-1	hSpCas9	negative selection	4705124
102186122	102186144	11	-	27760321	HL60	viability	ATGAACCTTTACCAAAACGAGG	YAP1	ENSG00000137693	0.1288546688005603	[138,100]	[143,65]	1	hSpCas9	negative selection	4705125
102205893	102205915	11	-	27760321	HL60	viability	TGACTGATTCTCTGGTTCATGG	YAP1	ENSG00000137693	0.11612550575425862	[530,445]	[424,436]	1	hSpCas9	negative selection	4705126
102205956	102205978	11	+	27760321	HL60	viability	GCCCACAGGGAGGCGTCATGGG	YAP1	ENSG00000137693	-0.5695885584232571	[791,617]	[447,318]	-6	hSpCas9	negative selection	4705127
102223629	102223651	11	-	27760321	HL60	viability	GTTGGTAACTGGCTACGCAGGG	YAP1	ENSG00000137693	0.1470906444136434	[539,454]	[326,576]	1	hSpCas9	negative selection	4705128
102111004	102111026	11	+	27760321	HT1080	viability	TCAGATCGTGCACGTCCGCGGG	YAP1	ENSG00000137693	-1.3082874084169558	[659,514]	[62,128]	-5	hSpCas9	negative selection	4788586
102162535	102162557	11	-	27760321	HT1080	viability	TCATATTCTGCTGCACTGGTGG	YAP1	ENSG00000137693	-0.07367368862642426	[572,446]	[172,214]	0	hSpCas9	negative selection	4788587
102186122	102186144	11	-	27760321	HT1080	viability	ATGAACCTTTACCAAAACGAGG	YAP1	ENSG00000137693	0.8194170734988773	[100,78]	[26,102]	4	hSpCas9	negative selection	4788588
102205893	102205915	11	-	27760321	HT1080	viability	TGACTGATTCTCTGGTTCATGG	YAP1	ENSG00000137693	2.8870338076076476	[445,347]	[1536,767]	9	hSpCas9	negative selection	4788589
102205956	102205978	11	+	27760321	HT1080	viability	GCCCACAGGGAGGCGTCATGGG	YAP1	ENSG00000137693	-1.6774149038461728	[617,481]	[78,56]	-6	hSpCas9	negative selection	4788590
102223629	102223651	11	-	27760321	HT1080	viability	GTTGGTAACTGGCTACGCAGGG	YAP1	ENSG00000137693	-0.26660654425767427	[454,354]	[125,142]	-1	hSpCas9	negative selection	4788591
102111004	102111026	11	+	27760321	HT29	viability after 7 days	TCAGATCGTGCACGTCCGCGGG	YAP1	ENSG00000137693	-0.4255738387946005	[659,514]	[336,620,691]	-6	hSpCas9	negative selection	4872049
102162535	102162557	11	-	27760321	HT29	viability after 7 days	TCATATTCTGCTGCACTGGTGG	YAP1	ENSG00000137693	-0.28639797282461865	[572,446]	[434,354,798]	-4	hSpCas9	negative selection	4872050
102186122	102186144	11	-	27760321	HT29	viability after 7 days	ATGAACCTTTACCAAAACGAGG	YAP1	ENSG00000137693	-0.7487801341574329	[100,78]	[152,43,22]	-8	hSpCas9	negative selection	4872051
102205893	102205915	11	-	27760321	HT29	viability after 7 days	TGACTGATTCTCTGGTTCATGG	YAP1	ENSG00000137693	-0.8949810878052538	[445,347]	[247,478,97]	-8	hSpCas9	negative selection	4872052
102205956	102205978	11	+	27760321	HT29	viability after 7 days	GCCCACAGGGAGGCGTCATGGG	YAP1	ENSG00000137693	-0.42324340588183373	[617,481]	[620,300,667]	-6	hSpCas9	negative selection	4872053
102223629	102223651	11	-	27760321	HT29	viability after 7 days	GTTGGTAACTGGCTACGCAGGG	YAP1	ENSG00000137693	-0.8969491336464401	[454,354]	[315,353,176]	-8	hSpCas9	negative selection	4872054
102111004	102111026	11	+	27760321	HT29	viability after 25 days	TCAGATCGTGCACGTCCGCGGG	YAP1	ENSG00000137693	-3.644667737205614	[659,514]	[44,49,67]	-9	hSpCas9	negative selection	4955512
102162535	102162557	11	-	27760321	HT29	viability after 25 days	TCATATTCTGCTGCACTGGTGG	YAP1	ENSG00000137693	-2.3537939150297476	[572,446]	[222,23,84]	-8	hSpCas9	negative selection	4955513
102186122	102186144	11	-	27760321	HT29	viability after 25 days	ATGAACCTTTACCAAAACGAGG	YAP1	ENSG00000137693	-2.1041410738783766	[100,78]	[14,35,20]	-8	hSpCas9	negative selection	4955514
102205893	102205915	11	-	27760321	HT29	viability after 25 days	TGACTGATTCTCTGGTTCATGG	YAP1	ENSG00000137693	-2.3135872615604964	[445,347]	[147,65,51]	-8	hSpCas9	negative selection	4955515
102205956	102205978	11	+	27760321	HT29	viability after 25 days	GCCCACAGGGAGGCGTCATGGG	YAP1	ENSG00000137693	-1.4120359074990079	[617,481]	[126,231,369]	-7	hSpCas9	negative selection	4955516
102223629	102223651	11	-	27760321	HT29	viability after 25 days	GTTGGTAACTGGCTACGCAGGG	YAP1	ENSG00000137693	-1.663369850050835	[454,354]	[109,92,247]	-7	hSpCas9	negative selection	4955517
102111004	102111026	11	+	27760321	HT29	viability after 22 days	TCAGATCGTGCACGTCCGCGGG	YAP1	ENSG00000137693	-3.0953362406473337	[659,514]	[152,46,35]	-8	hSpCas9	negative selection	5038975
102162535	102162557	11	-	27760321	HT29	viability after 22 days	TCATATTCTGCTGCACTGGTGG	YAP1	ENSG00000137693	-2.1815967301906696	[572,446]	[216,94,74]	-8	hSpCas9	negative selection	5038976
102186122	102186144	11	-	27760321	HT29	viability after 22 days	ATGAACCTTTACCAAAACGAGG	YAP1	ENSG00000137693	-1.7111996520719506	[100,78]	[42,23,27]	-8	hSpCas9	negative selection	5038977
102205893	102205915	11	-	27760321	HT29	viability after 22 days	TGACTGATTCTCTGGTTCATGG	YAP1	ENSG00000137693	-1.7254035116479798	[445,347]	[135,187,91]	-8	hSpCas9	negative selection	5038978
102205956	102205978	11	+	27760321	HT29	viability after 22 days	GCCCACAGGGAGGCGTCATGGG	YAP1	ENSG00000137693	-1.3835137360151148	[617,481]	[169,220,342]	-7	hSpCas9	negative selection	5038979
102223629	102223651	11	-	27760321	HT29	viability after 22 days	GTTGGTAACTGGCTACGCAGGG	YAP1	ENSG00000137693	-1.7663431916545016	[454,354]	[47,155,211]	-8	hSpCas9	negative selection	5038980
102111004	102111026	11	+	27760321	HT29	viability after 19 days	TCAGATCGTGCACGTCCGCGGG	YAP1	ENSG00000137693	-2.7034177648398914	[659,514]	[227,85,11]	-8	hSpCas9	negative selection	5122438
102162535	102162557	11	-	27760321	HT29	viability after 19 days	TCATATTCTGCTGCACTGGTGG	YAP1	ENSG00000137693	-1.3297112476876787	[572,446]	[140,461,88]	-7	hSpCas9	negative selection	5122439
102186122	102186144	11	-	27760321	HT29	viability after 19 days	ATGAACCTTTACCAAAACGAGG	YAP1	ENSG00000137693	-1.5137286314777108	[100,78]	[54,15,38]	-7	hSpCas9	negative selection	5122440
102205893	102205915	11	-	27760321	HT29	viability after 19 days	TGACTGATTCTCTGGTTCATGG	YAP1	ENSG00000137693	-1.4996627101543	[445,347]	[98,77,292]	-7	hSpCas9	negative selection	5122441
102205956	102205978	11	+	27760321	HT29	viability after 19 days	GCCCACAGGGAGGCGTCATGGG	YAP1	ENSG00000137693	-0.8823792742284107	[617,481]	[202,251,545]	-6	hSpCas9	negative selection	5122442
102223629	102223651	11	-	27760321	HT29	viability after 19 days	GTTGGTAACTGGCTACGCAGGG	YAP1	ENSG00000137693	-1.5861943673076988	[454,354]	[172,146,144]	-7	hSpCas9	negative selection	5122443
102111004	102111026	11	+	27760321	HT29	viability after 16 days	TCAGATCGTGCACGTCCGCGGG	YAP1	ENSG00000137693	-1.9381190226836003	[659,514]	[188,178,147]	-8	hSpCas9	negative selection	5205901
102162535	102162557	11	-	27760321	HT29	viability after 16 days	TCATATTCTGCTGCACTGGTGG	YAP1	ENSG00000137693	-1.8282545871317084	[572,446]	[94,152,227]	-8	hSpCas9	negative selection	5205902
102186122	102186144	11	-	27760321	HT29	viability after 16 days	ATGAACCTTTACCAAAACGAGG	YAP1	ENSG00000137693	-0.43593420910028713	[100,78]	[148,49,31]	-4	hSpCas9	negative selection	5205903
102205893	102205915	11	-	27760321	HT29	viability after 16 days	TGACTGATTCTCTGGTTCATGG	YAP1	ENSG00000137693	-1.4430301810259956	[445,347]	[124,217,141]	-8	hSpCas9	negative selection	5205904
102205956	102205978	11	+	27760321	HT29	viability after 16 days	GCCCACAGGGAGGCGTCATGGG	YAP1	ENSG00000137693	-0.27311487220434694	[617,481]	[397,508,609]	-3	hSpCas9	negative selection	5205905
102223629	102223651	11	-	27760321	HT29	viability after 16 days	GTTGGTAACTGGCTACGCAGGG	YAP1	ENSG00000137693	-1.209943980856536	[454,354]	[240,189,160]	-7	hSpCas9	negative selection	5205906
102111004	102111026	11	+	27760321	HT29	viability after 13 days	TCAGATCGTGCACGTCCGCGGG	YAP1	ENSG00000137693	-1.387665451582003	[659,514]	[480,177,129]	-8	hSpCas9	negative selection	5289364
102162535	102162557	11	-	27760321	HT29	viability after 13 days	TCATATTCTGCTGCACTGGTGG	YAP1	ENSG00000137693	-1.4245329161436642	[572,446]	[234,117,302]	-8	hSpCas9	negative selection	5289365
102186122	102186144	11	-	27760321	HT29	viability after 13 days	ATGAACCTTTACCAAAACGAGG	YAP1	ENSG00000137693	-0.18730127625200743	[100,78]	[49,163,62]	-2	hSpCas9	negative selection	5289366
102205893	102205915	11	-	27760321	HT29	viability after 13 days	TGACTGATTCTCTGGTTCATGG	YAP1	ENSG00000137693	-1.0743226379149489	[445,347]	[382,126,149]	-7	hSpCas9	negative selection	5289367
102205956	102205978	11	+	27760321	HT29	viability after 13 days	GCCCACAGGGAGGCGTCATGGG	YAP1	ENSG00000137693	-0.8480595120055893	[617,481]	[376,310,373]	-7	hSpCas9	negative selection	5289368
102223629	102223651	11	-	27760321	HT29	viability after 13 days	GTTGGTAACTGGCTACGCAGGG	YAP1	ENSG00000137693	-0.9752099679847573	[454,354]	[159,179,368]	-7	hSpCas9	negative selection	5289369
102111004	102111026	11	+	27760321	HT29	viability after 10 days	TCAGATCGTGCACGTCCGCGGG	YAP1	ENSG00000137693	-1.132330237513055	[659,514]	[275,324,400]	-8	hSpCas9	negative selection	5372827
102162535	102162557	11	-	27760321	HT29	viability after 10 days	TCATATTCTGCTGCACTGGTGG	YAP1	ENSG00000137693	-0.9311573049733134	[572,446]	[326,261,408]	-7	hSpCas9	negative selection	5372828
102186122	102186144	11	-	27760321	HT29	viability after 10 days	ATGAACCTTTACCAAAACGAGG	YAP1	ENSG00000137693	0.3675499630939707	[100,78]	[123,74,231]	5	hSpCas9	negative selection	5372829
102205893	102205915	11	-	27760321	HT29	viability after 10 days	TGACTGATTCTCTGGTTCATGG	YAP1	ENSG00000137693	-0.8101918801400114	[445,347]	[160,296,387]	-7	hSpCas9	negative selection	5372830
102205956	102205978	11	+	27760321	HT29	viability after 10 days	GCCCACAGGGAGGCGTCATGGG	YAP1	ENSG00000137693	-0.42954458771281534	[617,481]	[447,567,514]	-5	hSpCas9	negative selection	5372831
102223629	102223651	11	-	27760321	HT29	viability after 10 days	GTTGGTAACTGGCTACGCAGGG	YAP1	ENSG00000137693	-0.8542349262506587	[454,354]	[259,286,291]	-7	hSpCas9	negative selection	5372832
102111004	102111026	11	+	27760321	MOLM13	viability	TCAGATCGTGCACGTCCGCGGG	YAP1	ENSG00000137693	0.23717072852995202	[796,659]	[726,273]	1	hSpCas9	negative selection	5456290
102162535	102162557	11	-	27760321	MOLM13	viability	TCATATTCTGCTGCACTGGTGG	YAP1	ENSG00000137693	0.2476426078834203	[668,572]	[606,250]	1	hSpCas9	negative selection	5456291
102186122	102186144	11	-	27760321	MOLM13	viability	ATGAACCTTTACCAAAACGAGG	YAP1	ENSG00000137693	2.030916079990297	[138,100]	[569,21]	9	hSpCas9	negative selection	5456292
102205893	102205915	11	-	27760321	MOLM13	viability	TGACTGATTCTCTGGTTCATGG	YAP1	ENSG00000137693	0.7468773961447679	[530,445]	[692,262]	5	hSpCas9	negative selection	5456293
102205956	102205978	11	+	27760321	MOLM13	viability	GCCCACAGGGAGGCGTCATGGG	YAP1	ENSG00000137693	0.5637726551276487	[791,617]	[880,330]	4	hSpCas9	negative selection	5456294
102223629	102223651	11	-	27760321	MOLM13	viability	GTTGGTAACTGGCTACGCAGGG	YAP1	ENSG00000137693	0.6474447507661287	[539,454]	[551,340]	4	hSpCas9	negative selection	5456295
102110461	102110484	11	+	27661255	K562	viability	GCCGCCGCCAGGGAAAAGAAAGG	YAP1	ENSG00000137693	0.5751736469883493	[95,171]	[186,132]	9	dCas9-KRAB	negative selection	5523278
102110604	102110627	11	+	27661255	K562	viability	GTGCCTCGCAGCCCCTCCCGAGG	YAP1	ENSG00000137693	-0.018166519802146813	[540,899]	[647,490]	0	dCas9-KRAB	negative selection	5523279
102110815	102110838	11	+	27661255	K562	viability	GGTCAGGGGGTGCGCGTCGGGGG	YAP1	ENSG00000137693	-0.1281242373129533	[677,681]	[564,438]	-4	dCas9-KRAB	negative selection	5523280
102186110	102186133	11	+	27260156	BXPC3	viability	CCAAGGCTTGACCCTCGTTTTGG	YAP1	ENSG00000137693	0.4223944231792252	[538]	[616,744,853,825]	8	hSpCas9	negative selection	5580708
102162507	102162530	11	-	27260156	BXPC3	viability	TGGGGGCTGTGACGTTCATCTGG	YAP1	ENSG00000137693	0.09608855292021401	[740]	[912,772,824,783]	2	hSpCas9	negative selection	5580709
102205993	102206016	11	-	27260156	BXPC3	viability	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	0.3622443646607943	[461]	[638,598,681,550]	7	hSpCas9	negative selection	5580710
102186011	102186034	11	+	27260156	BXPC3	viability	ATTATAGGTCCTCTTCCTGATGG	YAP1	ENSG00000137693	0.05551298759582879	[686]	[600,838,723,837]	1	hSpCas9	negative selection	5644955
102205900	102205923	11	-	27260156	BXPC3	viability	GAGCACTCTGACTGATTCTCTGG	YAP1	ENSG00000137693	-0.035544127929166044	[465]	[444,381,494,600]	-1	hSpCas9	negative selection	5644956
102162458	102162481	11	+	27260156	BXPC3	viability	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	-0.6244463775607629	[230]	[165,118,146,199]	-8	hSpCas9	negative selection	5644957
102186110	102186133	11	+	27260156	A673	viability	CCAAGGCTTGACCCTCGTTTTGG	YAP1	ENSG00000137693	0.37519620202949305	[538]	[927,788,749,904]	8	hSpCas9	negative selection	5701959
102162507	102162530	11	-	27260156	A673	viability	TGGGGGCTGTGACGTTCATCTGG	YAP1	ENSG00000137693	0.08179809485857126	[740]	[1119,788,1015,858]	2	hSpCas9	negative selection	5701960
102205993	102206016	11	-	27260156	A673	viability	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	0.00794781666034626	[461]	[558,498,545,631]	0	hSpCas9	negative selection	5701961
102186011	102186034	11	+	27260156	A673	viability	ATTATAGGTCCTCTTCCTGATGG	YAP1	ENSG00000137693	-0.1681029215473817	[686]	[768,719,683,768]	-4	hSpCas9	negative selection	5766206
102205900	102205923	11	-	27260156	A673	viability	GAGCACTCTGACTGATTCTCTGG	YAP1	ENSG00000137693	-0.0037818553792010687	[465]	[622,515,526,574]	0	hSpCas9	negative selection	5766207
102162458	102162481	11	+	27260156	A673	viability	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	-0.0307855922707172	[230]	[294,254,320,213]	0	hSpCas9	negative selection	5766208
102186110	102186133	11	+	27260156	A375	viability	CCAAGGCTTGACCCTCGTTTTGG	YAP1	ENSG00000137693	0.4901974014981289	[538]	[952,1177,651,801]	7	hSpCas9	negative selection	5823210
102162507	102162530	11	-	27260156	A375	viability	TGGGGGCTGTGACGTTCATCTGG	YAP1	ENSG00000137693	0.6032340886633215	[740]	[1320,1225,1410,1286]	8	hSpCas9	negative selection	5823211
102205993	102206016	11	-	27260156	A375	viability	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	0.45785454851675395	[461]	[668,967,847,532]	6	hSpCas9	negative selection	5823212
102186011	102186034	11	+	27260156	A375	viability	ATTATAGGTCCTCTTCCTGATGG	YAP1	ENSG00000137693	-0.32654352012800725	[686]	[522,646,708,673]	-5	hSpCas9	negative selection	5887457
102205900	102205923	11	-	27260156	A375	viability	GAGCACTCTGACTGATTCTCTGG	YAP1	ENSG00000137693	-0.09674459929925627	[465]	[432,591,446,565]	-1	hSpCas9	negative selection	5887458
102162458	102162481	11	+	27260156	A375	viability	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	0.5815473870515837	[230]	[383,551,211,476]	8	hSpCas9	negative selection	5887459
102186110	102186133	11	+	27260156	COLO741	viability	CCAAGGCTTGACCCTCGTTTTGG	YAP1	ENSG00000137693	0.5520307780461451	[538]	[1053,1042,938]	9	hSpCas9	negative selection	5944461
102162507	102162530	11	-	27260156	COLO741	viability	TGGGGGCTGTGACGTTCATCTGG	YAP1	ENSG00000137693	0.1510466573498922	[740]	[1238,806,1115]	3	hSpCas9	negative selection	5944462
102205993	102206016	11	-	27260156	COLO741	viability	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	-0.08000764529340836	[461]	[578,540,555]	-2	hSpCas9	negative selection	5944463
102186011	102186034	11	+	27260156	COLO741	viability	ATTATAGGTCCTCTTCCTGATGG	YAP1	ENSG00000137693	-0.05952643246097972	[686]	[991,808,743]	-1	hSpCas9	negative selection	6008708
102205900	102205923	11	-	27260156	COLO741	viability	GAGCACTCTGACTGATTCTCTGG	YAP1	ENSG00000137693	0.04938062775049902	[465]	[652,704,500]	1	hSpCas9	negative selection	6008709
102162458	102162481	11	+	27260156	COLO741	viability	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	0.14257448918967763	[230]	[373,354,256]	3	hSpCas9	negative selection	6008710
102186110	102186133	11	+	27260156	CAL120	viability	CCAAGGCTTGACCCTCGTTTTGG	YAP1	ENSG00000137693	0.16858160663713806	[538]	[846,825,604]	2	hSpCas9	negative selection	6065712
102162507	102162530	11	-	27260156	CAL120	viability	TGGGGGCTGTGACGTTCATCTGG	YAP1	ENSG00000137693	0.3197571708443888	[740]	[1318,981,1175]	5	hSpCas9	negative selection	6065713
102205993	102206016	11	-	27260156	CAL120	viability	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	0.04815915054989014	[461]	[422,782,551]	0	hSpCas9	negative selection	6065714
102186011	102186034	11	+	27260156	CAL120	viability	ATTATAGGTCCTCTTCCTGATGG	YAP1	ENSG00000137693	-2.0608299919118664	[686]	[231,254,132]	-9	hSpCas9	negative selection	6129959
102205900	102205923	11	-	27260156	CAL120	viability	GAGCACTCTGACTGATTCTCTGG	YAP1	ENSG00000137693	-0.5809187108667305	[465]	[428,291,446]	-7	hSpCas9	negative selection	6129960
102162458	102162481	11	+	27260156	CAL120	viability	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	-2.6487178737112886	[230]	[33,15,84]	-9	hSpCas9	negative selection	6129961
102186110	102186133	11	+	27260156	CADOES1	viability	CCAAGGCTTGACCCTCGTTTTGG	YAP1	ENSG00000137693	0.5956802141169883	[538]	[893,598,894,636]	8	hSpCas9	negative selection	6186963
102162507	102162530	11	-	27260156	CADOES1	viability	TGGGGGCTGTGACGTTCATCTGG	YAP1	ENSG00000137693	0.29354770253680595	[740]	[857,892,854,769]	5	hSpCas9	negative selection	6186964
102205993	102206016	11	-	27260156	CADOES1	viability	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	0.34807783755928806	[461]	[460,558,568,600]	6	hSpCas9	negative selection	6186965
102186011	102186034	11	+	27260156	CADOES1	viability	ATTATAGGTCCTCTTCCTGATGG	YAP1	ENSG00000137693	-0.19526199451782378	[686]	[350,592,700,588]	-3	hSpCas9	negative selection	6251210
102205900	102205923	11	-	27260156	CADOES1	viability	GAGCACTCTGACTGATTCTCTGG	YAP1	ENSG00000137693	0.03616290417200513	[465]	[435,520,422,395]	0	hSpCas9	negative selection	6251211
102162458	102162481	11	+	27260156	CADOES1	viability	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	-0.2773494325556618	[230]	[220,234,103,147]	-5	hSpCas9	negative selection	6251212
102186110	102186133	11	+	27260156	EWS502	viability	CCAAGGCTTGACCCTCGTTTTGG	YAP1	ENSG00000137693	0.5081340972664872	[538]	[631,873,863,900]	8	hSpCas9	negative selection	6308214
102162507	102162530	11	-	27260156	EWS502	viability	TGGGGGCTGTGACGTTCATCTGG	YAP1	ENSG00000137693	0.32507990402979436	[740]	[840,875,1051,1197]	5	hSpCas9	negative selection	6308215
102205993	102206016	11	-	27260156	EWS502	viability	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	0.1680703095793884	[461]	[517,604,546,526]	3	hSpCas9	negative selection	6308216
102186011	102186034	11	+	27260156	EWS502	viability	ATTATAGGTCCTCTTCCTGATGG	YAP1	ENSG00000137693	-0.08421011492326214	[686]	[755,545,577,871]	-1	hSpCas9	negative selection	6372461
102205900	102205923	11	-	27260156	EWS502	viability	GAGCACTCTGACTGATTCTCTGG	YAP1	ENSG00000137693	0.03743095481423459	[465]	[523,461,471,569]	0	hSpCas9	negative selection	6372462
102162458	102162481	11	+	27260156	EWS502	viability	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	0.12790722275508648	[230]	[227,391,176,269]	2	hSpCas9	negative selection	6372463
102186110	102186133	11	+	27260156	EW8	viability	CCAAGGCTTGACCCTCGTTTTGG	YAP1	ENSG00000137693	0.3362904634299581	[538]	[676,629,503,415]	6	hSpCas9	negative selection	6429465
102162507	102162530	11	-	27260156	EW8	viability	TGGGGGCTGTGACGTTCATCTGG	YAP1	ENSG00000137693	-0.030739081355138365	[740]	[689,666,460,564]	0	hSpCas9	negative selection	6429466
102205993	102206016	11	-	27260156	EW8	viability	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	0.1599848858144981	[461]	[561,460,283,403]	3	hSpCas9	negative selection	6429467
102186011	102186034	11	+	27260156	EW8	viability	ATTATAGGTCCTCTTCCTGATGG	YAP1	ENSG00000137693	-0.043388474242423314	[686]	[691,500,421,580]	-1	hSpCas9	negative selection	6493712
102205900	102205923	11	-	27260156	EW8	viability	GAGCACTCTGACTGATTCTCTGG	YAP1	ENSG00000137693	0.39918290585116206	[465]	[595,508,388,525]	7	hSpCas9	negative selection	6493713
102162458	102162481	11	+	27260156	EW8	viability	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	0.08235371007004866	[230]	[247,190,214,140]	1	hSpCas9	negative selection	6493714
102186110	102186133	11	+	27260156	CORL105	viability	CCAAGGCTTGACCCTCGTTTTGG	YAP1	ENSG00000137693	0.3336839214308737	[538]	[476,735,1018,972]	6	hSpCas9	negative selection	6550716
102162507	102162530	11	-	27260156	CORL105	viability	TGGGGGCTGTGACGTTCATCTGG	YAP1	ENSG00000137693	0.037861451601028495	[740]	[1013,832,974,758]	0	hSpCas9	negative selection	6550717
102205993	102206016	11	-	27260156	CORL105	viability	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	-0.09732313235485732	[461]	[622,446,570,396]	-2	hSpCas9	negative selection	6550718
102186011	102186034	11	+	27260156	CORL105	viability	ATTATAGGTCCTCTTCCTGATGG	YAP1	ENSG00000137693	-0.2806534689051562	[686]	[710,601,843,522]	-5	hSpCas9	negative selection	6614963
102205900	102205923	11	-	27260156	CORL105	viability	GAGCACTCTGACTGATTCTCTGG	YAP1	ENSG00000137693	-0.0834678464638551	[465]	[542,470,501,542]	-1	hSpCas9	negative selection	6614964
102162458	102162481	11	+	27260156	CORL105	viability	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	-0.04105684714166147	[230]	[151,168,484,277]	-1	hSpCas9	negative selection	6614965
102186110	102186133	11	+	27260156	HS294T	viability	CCAAGGCTTGACCCTCGTTTTGG	YAP1	ENSG00000137693	0.5273243246408066	[538]	[243,267,299,413]	7	hSpCas9	negative selection	6671967
102162507	102162530	11	-	27260156	HS294T	viability	TGGGGGCTGTGACGTTCATCTGG	YAP1	ENSG00000137693	0.6754379853983471	[740]	[285,338,664,579]	8	hSpCas9	negative selection	6671968
102205993	102206016	11	-	27260156	HS294T	viability	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	-0.11824631202626652	[461]	[216,97,149,194]	-2	hSpCas9	negative selection	6671969
102186011	102186034	11	+	27260156	HS294T	viability	ATTATAGGTCCTCTTCCTGATGG	YAP1	ENSG00000137693	-0.32384033490547093	[686]	[262,144,232,202]	-4	hSpCas9	negative selection	6736214
102205900	102205923	11	-	27260156	HS294T	viability	GAGCACTCTGACTGATTCTCTGG	YAP1	ENSG00000137693	0.011080378366533136	[465]	[185,141,234,159]	0	hSpCas9	negative selection	6736215
102162458	102162481	11	+	27260156	HS294T	viability	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	-0.023587998870152616	[230]	[71,94,84,102]	0	hSpCas9	negative selection	6736216
102186110	102186133	11	+	27260156	HCC44	viability	CCAAGGCTTGACCCTCGTTTTGG	YAP1	ENSG00000137693	0.5915387229451321	[538]	[825,889,1074,898]	8	hSpCas9	negative selection	6793218
102162507	102162530	11	-	27260156	HCC44	viability	TGGGGGCTGTGACGTTCATCTGG	YAP1	ENSG00000137693	0.4347734971808338	[740]	[1001,1018,1190,1317]	7	hSpCas9	negative selection	6793219
102205993	102206016	11	-	27260156	HCC44	viability	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	0.09894883866982536	[461]	[488,552,583,604]	1	hSpCas9	negative selection	6793220
102186011	102186034	11	+	27260156	HCC44	viability	ATTATAGGTCCTCTTCCTGATGG	YAP1	ENSG00000137693	-0.8030260049623272	[686]	[505,525,582,188]	-8	hSpCas9	negative selection	6857465
102205900	102205923	11	-	27260156	HCC44	viability	GAGCACTCTGACTGATTCTCTGG	YAP1	ENSG00000137693	-0.01994448277240299	[465]	[520,392,601,588]	0	hSpCas9	negative selection	6857466
102162458	102162481	11	+	27260156	HCC44	viability	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	-0.15160575774486595	[230]	[300,219,277,157]	-2	hSpCas9	negative selection	6857467
102186110	102186133	11	+	27260156	G402	viability	CCAAGGCTTGACCCTCGTTTTGG	YAP1	ENSG00000137693	0.060545518592408754	[538]	[715,516,638,854]	0	hSpCas9	negative selection	6914469
102162507	102162530	11	-	27260156	G402	viability	TGGGGGCTGTGACGTTCATCTGG	YAP1	ENSG00000137693	0.2118116310846555	[740]	[1371,875,1084,895]	2	hSpCas9	negative selection	6914470
102205993	102206016	11	-	27260156	G402	viability	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	0.3610288435613265	[461]	[753,725,762,657]	4	hSpCas9	negative selection	6914471
102186011	102186034	11	+	27260156	G402	viability	ATTATAGGTCCTCTTCCTGATGG	YAP1	ENSG00000137693	-1.4189667455915291	[686]	[424,176,282,372]	-9	hSpCas9	negative selection	6978716
102205900	102205923	11	-	27260156	G402	viability	GAGCACTCTGACTGATTCTCTGG	YAP1	ENSG00000137693	-0.6681575235116833	[465]	[375,175,384,478]	-7	hSpCas9	negative selection	6978717
102162458	102162481	11	+	27260156	G402	viability	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	-1.6132612759113099	[230]	[60,77,28,189]	-9	hSpCas9	negative selection	6978718
102186110	102186133	11	+	27260156	L33	viability	CCAAGGCTTGACCCTCGTTTTGG	YAP1	ENSG00000137693	0.4554662762309683	[538]	[755,275,464,785]	8	hSpCas9	negative selection	7035720
102162507	102162530	11	-	27260156	L33	viability	TGGGGGCTGTGACGTTCATCTGG	YAP1	ENSG00000137693	0.09096970608363109	[740]	[765,319,553,729]	2	hSpCas9	negative selection	7035721
102205993	102206016	11	-	27260156	L33	viability	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	-0.025145717646413705	[461]	[402,183,302,482]	0	hSpCas9	negative selection	7035722
102186011	102186034	11	+	27260156	L33	viability	ATTATAGGTCCTCTTCCTGATGG	YAP1	ENSG00000137693	-0.5062980858826543	[686]	[581,190,254,477]	-8	hSpCas9	negative selection	7099967
102205900	102205923	11	-	27260156	L33	viability	GAGCACTCTGACTGATTCTCTGG	YAP1	ENSG00000137693	-0.0735540853231495	[465]	[388,206,258,465]	-2	hSpCas9	negative selection	7099968
102162458	102162481	11	+	27260156	L33	viability	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	-0.3783874547120596	[230]	[172,97,76,175]	-7	hSpCas9	negative selection	7099969
102186110	102186133	11	+	27260156	K562	viability	CCAAGGCTTGACCCTCGTTTTGG	YAP1	ENSG00000137693	0.8057682190816304	[538]	[1109,1018,567,692]	8	hSpCas9	negative selection	7156971
102162507	102162530	11	-	27260156	K562	viability	TGGGGGCTGTGACGTTCATCTGG	YAP1	ENSG00000137693	0.001367517320687961	[740]	[789,680,625,556]	0	hSpCas9	negative selection	7156972
102205993	102206016	11	-	27260156	K562	viability	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	0.5829828425937412	[461]	[846,583,459,583]	7	hSpCas9	negative selection	7156973
102186011	102186034	11	+	27260156	K562	viability	ATTATAGGTCCTCTTCCTGATGG	YAP1	ENSG00000137693	-0.3331889848636448	[686]	[533,578,347,481]	-4	hSpCas9	negative selection	7221218
102205900	102205923	11	-	27260156	K562	viability	GAGCACTCTGACTGATTCTCTGG	YAP1	ENSG00000137693	0.2918396979155811	[465]	[561,530,648,309]	3	hSpCas9	negative selection	7221219
102162458	102162481	11	+	27260156	K562	viability	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	0.05152328061214484	[230]	[338,148,193,177]	0	hSpCas9	negative selection	7221220
102186110	102186133	11	+	27260156	HT29	viability	CCAAGGCTTGACCCTCGTTTTGG	YAP1	ENSG00000137693	0.24852960223085563	[538]	[814,864,846,611]	5	hSpCas9	negative selection	7278222
102162507	102162530	11	-	27260156	HT29	viability	TGGGGGCTGTGACGTTCATCTGG	YAP1	ENSG00000137693	0.11223367171292253	[740]	[1036,1059,1001,819]	2	hSpCas9	negative selection	7278223
102205993	102206016	11	-	27260156	HT29	viability	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	0.174130864654022	[461]	[785,518,701,536]	3	hSpCas9	negative selection	7278224
102186011	102186034	11	+	27260156	HT29	viability	ATTATAGGTCCTCTTCCTGATGG	YAP1	ENSG00000137693	-0.3591142444016214	[686]	[722,712,563,614]	-6	hSpCas9	negative selection	7342469
102205900	102205923	11	-	27260156	HT29	viability	GAGCACTCTGACTGATTCTCTGG	YAP1	ENSG00000137693	-0.34622579045934776	[465]	[476,422,463,418]	-6	hSpCas9	negative selection	7342470
102162458	102162481	11	+	27260156	HT29	viability	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	-1.2390094157044254	[230]	[117,99,34,208]	-9	hSpCas9	negative selection	7342471
102186110	102186133	11	+	27260156	MHHES1	viability	CCAAGGCTTGACCCTCGTTTTGG	YAP1	ENSG00000137693	0.23801319653714315	[538]	[757,852,553,702]	4	hSpCas9	negative selection	7399473
102162507	102162530	11	-	27260156	MHHES1	viability	TGGGGGCTGTGACGTTCATCTGG	YAP1	ENSG00000137693	0.19679242146727705	[740]	[1156,698,1236,757]	3	hSpCas9	negative selection	7399474
102205993	102206016	11	-	27260156	MHHES1	viability	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	0.052221449696579006	[461]	[524,605,529,498]	1	hSpCas9	negative selection	7399475
102186011	102186034	11	+	27260156	MHHES1	viability	ATTATAGGTCCTCTTCCTGATGG	YAP1	ENSG00000137693	-0.36163220533349394	[686]	[744,495,704,483]	-6	hSpCas9	negative selection	7463720
102205900	102205923	11	-	27260156	MHHES1	viability	GAGCACTCTGACTGATTCTCTGG	YAP1	ENSG00000137693	0.13513303011067895	[465]	[627,865,459,411]	2	hSpCas9	negative selection	7463721
102162458	102162481	11	+	27260156	MHHES1	viability	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	-0.6840997601509842	[230]	[209,176,132,136]	-8	hSpCas9	negative selection	7463722
102186110	102186133	11	+	27260156	MEWO	viability	CCAAGGCTTGACCCTCGTTTTGG	YAP1	ENSG00000137693	0.5518191384362585	[538]	[832,671,730]	9	hSpCas9	negative selection	7520724
102162507	102162530	11	-	27260156	MEWO	viability	TGGGGGCTGTGACGTTCATCTGG	YAP1	ENSG00000137693	-0.05456951938183996	[740]	[855,651,530]	-1	hSpCas9	negative selection	7520725
102205993	102206016	11	-	27260156	MEWO	viability	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	0.19391785137128204	[461]	[596,494,410]	4	hSpCas9	negative selection	7520726
102186011	102186034	11	+	27260156	MEWO	viability	ATTATAGGTCCTCTTCCTGATGG	YAP1	ENSG00000137693	-0.45775508631823336	[686]	[550,453,414]	-7	hSpCas9	negative selection	7584971
102205900	102205923	11	-	27260156	MEWO	viability	GAGCACTCTGACTGATTCTCTGG	YAP1	ENSG00000137693	0.10536799087083791	[465]	[561,453,408]	2	hSpCas9	negative selection	7584972
102162458	102162481	11	+	27260156	MEWO	viability	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	0.19328942733016674	[230]	[389,231,146]	4	hSpCas9	negative selection	7584973
102186110	102186133	11	+	27260156	LNCAPCLONEFGC	viability	CCAAGGCTTGACCCTCGTTTTGG	YAP1	ENSG00000137693	0.7754007188583703	[538]	[896,788,860,800]	9	hSpCas9	negative selection	7641975
102162507	102162530	11	-	27260156	LNCAPCLONEFGC	viability	TGGGGGCTGTGACGTTCATCTGG	YAP1	ENSG00000137693	0.42882186339357264	[740]	[855,842,1141,812]	6	hSpCas9	negative selection	7641976
102205993	102206016	11	-	27260156	LNCAPCLONEFGC	viability	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	0.3533124566682754	[461]	[430,573,624,520]	5	hSpCas9	negative selection	7641977
102186011	102186034	11	+	27260156	LNCAPCLONEFGC	viability	ATTATAGGTCCTCTTCCTGATGG	YAP1	ENSG00000137693	-0.39210896406013396	[686]	[398,562,479,450]	-6	hSpCas9	negative selection	7706222
102205900	102205923	11	-	27260156	LNCAPCLONEFGC	viability	GAGCACTCTGACTGATTCTCTGG	YAP1	ENSG00000137693	-0.02865064872791709	[465]	[343,426,470,421]	0	hSpCas9	negative selection	7706223
102162458	102162481	11	+	27260156	LNCAPCLONEFGC	viability	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	0.4695171999977025	[230]	[297,261,306,295]	7	hSpCas9	negative selection	7706224
102186110	102186133	11	+	27260156	PANC0327	viability	CCAAGGCTTGACCCTCGTTTTGG	YAP1	ENSG00000137693	0.38141919177882205	[538]	[772,606,597,530]	5	hSpCas9	negative selection	7763226
102162507	102162530	11	-	27260156	PANC0327	viability	TGGGGGCTGTGACGTTCATCTGG	YAP1	ENSG00000137693	0.20562295257286467	[740]	[906,735,664,742]	3	hSpCas9	negative selection	7763227
102205993	102206016	11	-	27260156	PANC0327	viability	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	0.17658900096452818	[461]	[439,671,244,468]	2	hSpCas9	negative selection	7763228
102186011	102186034	11	+	27260156	PANC0327	viability	ATTATAGGTCCTCTTCCTGATGG	YAP1	ENSG00000137693	-0.8177019620442434	[686]	[249,201,605,337]	-8	hSpCas9	negative selection	7827473
102205900	102205923	11	-	27260156	PANC0327	viability	GAGCACTCTGACTGATTCTCTGG	YAP1	ENSG00000137693	0.2834453647262798	[465]	[318,595,491,580]	4	hSpCas9	negative selection	7827474
102162458	102162481	11	+	27260156	PANC0327	viability	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	-0.5421132119815053	[230]	[126,136,138,159]	-6	hSpCas9	negative selection	7827475
102186110	102186133	11	+	27260156	NCIH2009	viability	CCAAGGCTTGACCCTCGTTTTGG	YAP1	ENSG00000137693	0.8222941777268535	[538]	[1595,1097,1354]	9	hSpCas9	negative selection	7884477
102162507	102162530	11	-	27260156	NCIH2009	viability	TGGGGGCTGTGACGTTCATCTGG	YAP1	ENSG00000137693	0.5456477245402745	[740]	[1672,1620,1266]	7	hSpCas9	negative selection	7884478
102205993	102206016	11	-	27260156	NCIH2009	viability	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	0.21814173749663818	[461]	[889,738,649]	3	hSpCas9	negative selection	7884479
102186011	102186034	11	+	27260156	NCIH2009	viability	ATTATAGGTCCTCTTCCTGATGG	YAP1	ENSG00000137693	-0.7069964084178497	[686]	[674,377,730]	-7	hSpCas9	negative selection	7948724
102205900	102205923	11	-	27260156	NCIH2009	viability	GAGCACTCTGACTGATTCTCTGG	YAP1	ENSG00000137693	-0.10491055065629594	[465]	[821,495,541]	-1	hSpCas9	negative selection	7948725
102162458	102162481	11	+	27260156	NCIH2009	viability	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	-0.3376263060178899	[230]	[247,161,355]	-4	hSpCas9	negative selection	7948726
102186110	102186133	11	+	27260156	NCIH1373	viability	CCAAGGCTTGACCCTCGTTTTGG	YAP1	ENSG00000137693	1.1795108760295083	[538]	[1563,1697,1084,289]	9	hSpCas9	negative selection	8005728
102162507	102162530	11	-	27260156	NCIH1373	viability	TGGGGGCTGTGACGTTCATCTGG	YAP1	ENSG00000137693	0.5842533976062386	[740]	[1646,979,1121,347]	6	hSpCas9	negative selection	8005729
102205993	102206016	11	-	27260156	NCIH1373	viability	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	0.6155352789175332	[461]	[620,586,1090,226]	6	hSpCas9	negative selection	8005730
102186011	102186034	11	+	27260156	NCIH1373	viability	ATTATAGGTCCTCTTCCTGATGG	YAP1	ENSG00000137693	-0.44655161767454665	[686]	[333,566,699,162]	-4	hSpCas9	negative selection	8069975
102205900	102205923	11	-	27260156	NCIH1373	viability	GAGCACTCTGACTGATTCTCTGG	YAP1	ENSG00000137693	0.11546532251730486	[465]	[750,398,666,126]	1	hSpCas9	negative selection	8069976
102162458	102162481	11	+	27260156	NCIH1373	viability	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	0.7024952063621072	[230]	[532,446,402,80]	7	hSpCas9	negative selection	8069977
102186110	102186133	11	+	27260156	PATU8902	viability	CCAAGGCTTGACCCTCGTTTTGG	YAP1	ENSG00000137693	0.005728438864083085	[538]	[787,973,721,502]	0	hSpCas9	negative selection	8126979
102162507	102162530	11	-	27260156	PATU8902	viability	TGGGGGCTGTGACGTTCATCTGG	YAP1	ENSG00000137693	0.7657491779127695	[740]	[1762,1812,1029,2699]	7	hSpCas9	negative selection	8126980
102205993	102206016	11	-	27260156	PATU8902	viability	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	-0.2884250755715262	[461]	[448,828,494,314]	-3	hSpCas9	negative selection	8126981
102186011	102186034	11	+	27260156	PATU8902	viability	ATTATAGGTCCTCTTCCTGATGG	YAP1	ENSG00000137693	-0.843187579650426	[686]	[465,387,562,727]	-7	hSpCas9	negative selection	8191226
102205900	102205923	11	-	27260156	PATU8902	viability	GAGCACTCTGACTGATTCTCTGG	YAP1	ENSG00000137693	0.26276984007978915	[465]	[867,578,934,670]	2	hSpCas9	negative selection	8191227
102162458	102162481	11	+	27260156	PATU8902	viability	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	0.32027057819057025	[230]	[237,402,351,655]	3	hSpCas9	negative selection	8191228
102186110	102186133	11	+	27260156	PANC1	viability	CCAAGGCTTGACCCTCGTTTTGG	YAP1	ENSG00000137693	0.8306562429519637	[538]	[599,963,1017,745]	9	hSpCas9	negative selection	8248230
102162507	102162530	11	-	27260156	PANC1	viability	TGGGGGCTGTGACGTTCATCTGG	YAP1	ENSG00000137693	0.36433432136063926	[740]	[779,894,900,720]	6	hSpCas9	negative selection	8248231
102205993	102206016	11	-	27260156	PANC1	viability	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	0.11968326524954268	[461]	[550,477,309,390]	1	hSpCas9	negative selection	8248232
102186011	102186034	11	+	27260156	PANC1	viability	ATTATAGGTCCTCTTCCTGATGG	YAP1	ENSG00000137693	-0.09295431422789302	[686]	[608,646,625,370]	-1	hSpCas9	negative selection	8312477
102205900	102205923	11	-	27260156	PANC1	viability	GAGCACTCTGACTGATTCTCTGG	YAP1	ENSG00000137693	-0.15842876393916022	[465]	[380,447,300,321]	-3	hSpCas9	negative selection	8312478
102162458	102162481	11	+	27260156	PANC1	viability	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	-0.13379207460202136	[230]	[147,175,153,232]	-2	hSpCas9	negative selection	8312479
102186110	102186133	11	+	27260156	PANC0813	viability	CCAAGGCTTGACCCTCGTTTTGG	YAP1	ENSG00000137693	0.7280322887276298	[538]	[1423,782,944,1073]	9	hSpCas9	negative selection	8369481
102162507	102162530	11	-	27260156	PANC0813	viability	TGGGGGCTGTGACGTTCATCTGG	YAP1	ENSG00000137693	0.409904083794549	[740]	[1103,1385,1024,1105]	6	hSpCas9	negative selection	8369482
102205993	102206016	11	-	27260156	PANC0813	viability	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	0.3507473869238057	[461]	[1042,691,543,528]	5	hSpCas9	negative selection	8369483
102186011	102186034	11	+	27260156	PANC0813	viability	ATTATAGGTCCTCTTCCTGATGG	YAP1	ENSG00000137693	-0.5660980139583043	[686]	[719,500,428,544]	-7	hSpCas9	negative selection	8433728
102205900	102205923	11	-	27260156	PANC0813	viability	GAGCACTCTGACTGATTCTCTGG	YAP1	ENSG00000137693	0.3808055907616948	[465]	[748,720,637,742]	6	hSpCas9	negative selection	8433729
102162458	102162481	11	+	27260156	PANC0813	viability	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	-0.30911240770407233	[230]	[204,238,136,288]	-5	hSpCas9	negative selection	8433730
102186110	102186133	11	+	27260156	RDES	viability	CCAAGGCTTGACCCTCGTTTTGG	YAP1	ENSG00000137693	0.36388264925713215	[538]	[754,625,728,1128]	6	hSpCas9	negative selection	8490732
102162507	102162530	11	-	27260156	RDES	viability	TGGGGGCTGTGACGTTCATCTGG	YAP1	ENSG00000137693	0.2921696456302496	[740]	[1076,974,939,1157]	5	hSpCas9	negative selection	8490733
102205993	102206016	11	-	27260156	RDES	viability	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	0.29513502765457417	[461]	[461,641,663,901]	5	hSpCas9	negative selection	8490734
102186011	102186034	11	+	27260156	RDES	viability	ATTATAGGTCCTCTTCCTGATGG	YAP1	ENSG00000137693	-0.2254684561000131	[686]	[506,694,714,824]	-4	hSpCas9	negative selection	8554979
102205900	102205923	11	-	27260156	RDES	viability	GAGCACTCTGACTGATTCTCTGG	YAP1	ENSG00000137693	-0.09187693075078711	[465]	[415,567,436,598]	-1	hSpCas9	negative selection	8554980
102162458	102162481	11	+	27260156	RDES	viability	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	-0.11236572883924012	[230]	[142,203,421,239]	-2	hSpCas9	negative selection	8554981
102186110	102186133	11	+	27260156	PC3	viability	CCAAGGCTTGACCCTCGTTTTGG	YAP1	ENSG00000137693	0.4797601258133593	[538]	[460,775,1384,671]	8	hSpCas9	negative selection	8611983
102162507	102162530	11	-	27260156	PC3	viability	TGGGGGCTGTGACGTTCATCTGG	YAP1	ENSG00000137693	0.3691991761603607	[740]	[609,912,1834,855]	7	hSpCas9	negative selection	8611984
102205993	102206016	11	-	27260156	PC3	viability	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	0.0714935261167722	[461]	[369,428,974,343]	1	hSpCas9	negative selection	8611985
102186011	102186034	11	+	27260156	PC3	viability	ATTATAGGTCCTCTTCCTGATGG	YAP1	ENSG00000137693	-0.31205490116320966	[686]	[382,522,952,518]	-6	hSpCas9	negative selection	8676230
102205900	102205923	11	-	27260156	PC3	viability	GAGCACTCTGACTGATTCTCTGG	YAP1	ENSG00000137693	-0.16588723919523643	[465]	[238,464,686,406]	-4	hSpCas9	negative selection	8676231
102162458	102162481	11	+	27260156	PC3	viability	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	-0.41797215170551816	[230]	[69,240,169,238]	-7	hSpCas9	negative selection	8676232
102186110	102186133	11	+	27260156	PATU8988T	viability	CCAAGGCTTGACCCTCGTTTTGG	YAP1	ENSG00000137693	-0.32365153382460693	[538]	[446,539,344,338]	-5	hSpCas9	negative selection	8733234
102162507	102162530	11	-	27260156	PATU8988T	viability	TGGGGGCTGTGACGTTCATCTGG	YAP1	ENSG00000137693	0.0355987084322692	[740]	[813,729,679,709]	0	hSpCas9	negative selection	8733235
102205993	102206016	11	-	27260156	PATU8988T	viability	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	0.41968936537572044	[461]	[626,441,593,720]	7	hSpCas9	negative selection	8733236
102186011	102186034	11	+	27260156	PATU8988T	viability	ATTATAGGTCCTCTTCCTGATGG	YAP1	ENSG00000137693	-0.5542535075249785	[686]	[228,774,240,608]	-7	hSpCas9	negative selection	8797481
102205900	102205923	11	-	27260156	PATU8988T	viability	GAGCACTCTGACTGATTCTCTGG	YAP1	ENSG00000137693	-0.08962408895299799	[465]	[268,543,518,365]	-1	hSpCas9	negative selection	8797482
102162458	102162481	11	+	27260156	PATU8988T	viability	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	-1.1013549163501803	[230]	[84,120,74,139]	-9	hSpCas9	negative selection	8797483
102186110	102186133	11	+	27260156	T47D	viability	CCAAGGCTTGACCCTCGTTTTGG	YAP1	ENSG00000137693	0.06904995773467892	[538]	[721,635,548,733]	1	hSpCas9	negative selection	8854485
102162507	102162530	11	-	27260156	T47D	viability	TGGGGGCTGTGACGTTCATCTGG	YAP1	ENSG00000137693	0.130571058799965	[740]	[907,995,996,870]	2	hSpCas9	negative selection	8854486
102205993	102206016	11	-	27260156	T47D	viability	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	0.18974715159428285	[461]	[572,592,715,571]	4	hSpCas9	negative selection	8854487
102186011	102186034	11	+	27260156	T47D	viability	ATTATAGGTCCTCTTCCTGATGG	YAP1	ENSG00000137693	-0.7316951123474345	[686]	[536,428,514,449]	-8	hSpCas9	negative selection	8918732
102205900	102205923	11	-	27260156	T47D	viability	GAGCACTCTGACTGATTCTCTGG	YAP1	ENSG00000137693	-0.315693321710424	[465]	[446,367,388,550]	-6	hSpCas9	negative selection	8918733
102162458	102162481	11	+	27260156	T47D	viability	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	-1.2001176872267703	[230]	[123,114,127,100]	-9	hSpCas9	negative selection	8918734
102186110	102186133	11	+	27260156	SU8686	viability	CCAAGGCTTGACCCTCGTTTTGG	YAP1	ENSG00000137693	0.4294975713107469	[538]	[585,811,782,692]	7	hSpCas9	negative selection	8975736
102162507	102162530	11	-	27260156	SU8686	viability	TGGGGGCTGTGACGTTCATCTGG	YAP1	ENSG00000137693	0.3999037254066601	[740]	[749,802,1331,1055]	6	hSpCas9	negative selection	8975737
102205993	102206016	11	-	27260156	SU8686	viability	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	0.19710140670255993	[461]	[546,520,436,598]	3	hSpCas9	negative selection	8975738
102186011	102186034	11	+	27260156	SU8686	viability	ATTATAGGTCCTCTTCCTGATGG	YAP1	ENSG00000137693	-0.2456944833563448	[686]	[487,395,746,724]	-4	hSpCas9	negative selection	9039983
102205900	102205923	11	-	27260156	SU8686	viability	GAGCACTCTGACTGATTCTCTGG	YAP1	ENSG00000137693	-0.20761902784257535	[465]	[323,372,445,480]	-4	hSpCas9	negative selection	9039984
102162458	102162481	11	+	27260156	SU8686	viability	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	-0.05236707296887877	[230]	[193,204,188,312]	-1	hSpCas9	negative selection	9039985
102186110	102186133	11	+	27260156	SKES1	viability	CCAAGGCTTGACCCTCGTTTTGG	YAP1	ENSG00000137693	0.5383395945385774	[538]	[1014,786,711,650]	9	hSpCas9	negative selection	9096987
102162507	102162530	11	-	27260156	SKES1	viability	TGGGGGCTGTGACGTTCATCTGG	YAP1	ENSG00000137693	0.06986504226259438	[740]	[1002,775,705,656]	1	hSpCas9	negative selection	9096988
102205993	102206016	11	-	27260156	SKES1	viability	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	0.1876614302301588	[461]	[535,576,510,482]	4	hSpCas9	negative selection	9096989
102186011	102186034	11	+	27260156	SKES1	viability	ATTATAGGTCCTCTTCCTGATGG	YAP1	ENSG00000137693	-0.061208343495278095	[686]	[830,670,671,491]	-1	hSpCas9	negative selection	9161234
102205900	102205923	11	-	27260156	SKES1	viability	GAGCACTCTGACTGATTCTCTGG	YAP1	ENSG00000137693	0.21104351052040596	[465]	[706,546,451,473]	4	hSpCas9	negative selection	9161235
102162458	102162481	11	+	27260156	SKES1	viability	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	0.3492364624967845	[230]	[349,329,258,249]	7	hSpCas9	negative selection	9161236
102186110	102186133	11	+	27260156	TOV112D	viability	CCAAGGCTTGACCCTCGTTTTGG	YAP1	ENSG00000137693	0.6526306204292458	[538]	[880,1118,743,721]	9	hSpCas9	negative selection	9218238
102162507	102162530	11	-	27260156	TOV112D	viability	TGGGGGCTGTGACGTTCATCTGG	YAP1	ENSG00000137693	0.3339200276403944	[740]	[809,1206,936,844]	6	hSpCas9	negative selection	9218239
102205993	102206016	11	-	27260156	TOV112D	viability	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	0.25015805211031367	[461]	[716,592,475,441]	5	hSpCas9	negative selection	9218240
102186011	102186034	11	+	27260156	TOV112D	viability	ATTATAGGTCCTCTTCCTGATGG	YAP1	ENSG00000137693	0.05261570715027297	[686]	[732,935,647,595]	1	hSpCas9	negative selection	9282485
102205900	102205923	11	-	27260156	TOV112D	viability	GAGCACTCTGACTGATTCTCTGG	YAP1	ENSG00000137693	-0.22482356581066099	[465]	[464,469,330,354]	-4	hSpCas9	negative selection	9282486
102162458	102162481	11	+	27260156	TOV112D	viability	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	-0.13700227120312714	[230]	[286,342,172,80]	-3	hSpCas9	negative selection	9282487
102186110	102186133	11	+	27260156	TC71	viability	CCAAGGCTTGACCCTCGTTTTGG	YAP1	ENSG00000137693	0.4935634437007946	[538]	[848,829,728,849]	9	hSpCas9	negative selection	9339489
102162507	102162530	11	-	27260156	TC71	viability	TGGGGGCTGTGACGTTCATCTGG	YAP1	ENSG00000137693	0.03192582956466239	[740]	[791,854,704,905]	0	hSpCas9	negative selection	9339490
102205993	102206016	11	-	27260156	TC71	viability	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	0.03159306373915021	[461]	[469,392,569,595]	0	hSpCas9	negative selection	9339491
102186011	102186034	11	+	27260156	TC71	viability	ATTATAGGTCCTCTTCCTGATGG	YAP1	ENSG00000137693	0.07889496021578535	[686]	[755,841,796,711]	2	hSpCas9	negative selection	9403736
102205900	102205923	11	-	27260156	TC71	viability	GAGCACTCTGACTGATTCTCTGG	YAP1	ENSG00000137693	0.037611402062727416	[465]	[552,543,414,542]	1	hSpCas9	negative selection	9403737
102162458	102162481	11	+	27260156	TC71	viability	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	0.04296350915951386	[230]	[243,317,197,262]	1	hSpCas9	negative selection	9403738
102186110	102186133	11	+	27260156	TC32	viability	CCAAGGCTTGACCCTCGTTTTGG	YAP1	ENSG00000137693	0.5738622604517083	[538]	[848,590,843,748]	8	hSpCas9	negative selection	9460740
102162507	102162530	11	-	27260156	TC32	viability	TGGGGGCTGTGACGTTCATCTGG	YAP1	ENSG00000137693	0.4044434663625788	[740]	[838,686,1138,1114]	7	hSpCas9	negative selection	9460741
102205993	102206016	11	-	27260156	TC32	viability	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	0.046350937719795544	[461]	[545,221,612,490]	0	hSpCas9	negative selection	9460742
102186011	102186034	11	+	27260156	TC32	viability	ATTATAGGTCCTCTTCCTGATGG	YAP1	ENSG00000137693	-0.23703145510648133	[686]	[505,388,816,559]	-4	hSpCas9	negative selection	9524987
102205900	102205923	11	-	27260156	TC32	viability	GAGCACTCTGACTGATTCTCTGG	YAP1	ENSG00000137693	-0.037738865811276376	[465]	[278,255,640,640]	0	hSpCas9	negative selection	9524988
102162458	102162481	11	+	27260156	TC32	viability	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	0.03835185819482034	[230]	[160,242,230,244]	0	hSpCas9	negative selection	9524989
102110992	102111015	11	-	27869803	HPAFII	viability after 27 days	GCACGATCTGATGCCCGGCGGGG	YAP1	ENSG00000137693	-1.194816176984023	[455]	[191,31,NaN]	-7	hSpCas9	negative selection	9539407
102111003	102111026	11	+	27869803	HPAFII	viability after 27 days	ATCAGATCGTGCACGTCCGCGGG	YAP1	ENSG00000137693	-2.3002870970268954	[223]	[12,32,NaN]	-8	hSpCas9	negative selection	9539408
102111157	102111180	11	-	27869803	HPAFII	viability after 27 days	ACGAGGTTACCTGTCGGGAGTGG	YAP1	ENSG00000137693	-0.23154588107402677	[241]	[97,116,NaN]	-2	hSpCas9	negative selection	9539409
102162497	102162520	11	-	27869803	HPAFII	viability after 27 days	GACGTTCATCTGGGACAGCATGG	YAP1	ENSG00000137693	-1.4476700773311961	[232]	[81,13,NaN]	-7	hSpCas9	negative selection	9539410
102229724	102229747	11	-	27869803	HPAFII	viability after 27 days	AACGGTTCTGCTGTGAGGGCAGG	YAP1	ENSG00000137693	-1.2129635236942826	[94]	[14,26,NaN]	-7	hSpCas9	negative selection	9539411
102110992	102111015	11	-	27869803	HPAFII	viability after 15 days	GCACGATCTGATGCCCGGCGGGG	YAP1	ENSG00000137693	-0.3333493501121457	[455]	[597,258,NaN]	-4	hSpCas9	negative selection	9621856
102111003	102111026	11	+	27869803	HPAFII	viability after 15 days	ATCAGATCGTGCACGTCCGCGGG	YAP1	ENSG00000137693	-0.6442447688550897	[223]	[137,163,NaN]	-6	hSpCas9	negative selection	9621857
102111157	102111180	11	-	27869803	HPAFII	viability after 15 days	ACGAGGTTACCTGTCGGGAGTGG	YAP1	ENSG00000137693	-0.06531499275029608	[241]	[308,210,NaN]	0	hSpCas9	negative selection	9621858
102162497	102162520	11	-	27869803	HPAFII	viability after 15 days	GACGTTCATCTGGGACAGCATGG	YAP1	ENSG00000137693	-0.5628385212531222	[232]	[216,139,NaN]	-6	hSpCas9	negative selection	9621859
102229724	102229747	11	-	27869803	HPAFII	viability after 15 days	AACGGTTCTGCTGTGAGGGCAGG	YAP1	ENSG00000137693	-1.8426401669102137	[94]	[25,29,NaN]	-9	hSpCas9	negative selection	9621860
102110992	102111015	11	-	27869803	ASPC1	viability after 36 days	GCACGATCTGATGCCCGGCGGGG	YAP1	ENSG00000137693	-2.173244182322099	[1221]	[190,62,50]	-9	hSpCas9	negative selection	9704305
102111003	102111026	11	+	27869803	ASPC1	viability after 36 days	ATCAGATCGTGCACGTCCGCGGG	YAP1	ENSG00000137693	-0.49663311756884543	[655]	[121,209,150]	-5	hSpCas9	negative selection	9704306
102111157	102111180	11	-	27869803	ASPC1	viability after 36 days	ACGAGGTTACCTGTCGGGAGTGG	YAP1	ENSG00000137693	-0.08922723184854464	[497]	[243,213,64]	-1	hSpCas9	negative selection	9704307
102162497	102162520	11	-	27869803	ASPC1	viability after 36 days	GACGTTCATCTGGGACAGCATGG	YAP1	ENSG00000137693	-0.24570028363487173	[646]	[23,244,261]	-3	hSpCas9	negative selection	9704308
102229724	102229747	11	-	27869803	ASPC1	viability after 36 days	AACGGTTCTGCTGTGAGGGCAGG	YAP1	ENSG00000137693	-0.8775777399827986	[194]	[58,20,33]	-7	hSpCas9	negative selection	9704309
102110992	102111015	11	-	27869803	PATU8988S	viability after 35 days	GCACGATCTGATGCCCGGCGGGG	YAP1	ENSG00000137693	-2.5215499862621873	[1076]	[93,56,NaN]	-9	hSpCas9	negative selection	9786754
102111003	102111026	11	+	27869803	PATU8988S	viability after 35 days	ATCAGATCGTGCACGTCCGCGGG	YAP1	ENSG00000137693	-3.168707207326335	[691]	[27,33,NaN]	-9	hSpCas9	negative selection	9786755
102111157	102111180	11	-	27869803	PATU8988S	viability after 35 days	ACGAGGTTACCTGTCGGGAGTGG	YAP1	ENSG00000137693	-1.3051108817602528	[392]	[87,39,NaN]	-8	hSpCas9	negative selection	9786756
102162497	102162520	11	-	27869803	PATU8988S	viability after 35 days	GACGTTCATCTGGGACAGCATGG	YAP1	ENSG00000137693	-1.3291844891912983	[507]	[49,112,NaN]	-8	hSpCas9	negative selection	9786757
102229724	102229747	11	-	27869803	PATU8988S	viability after 35 days	AACGGTTCTGCTGTGAGGGCAGG	YAP1	ENSG00000137693	0.7811109848409271	[175]	[38,204,NaN]	8	hSpCas9	negative selection	9786758
102110992	102111015	11	-	27869803	PATU8988S	viability after 31 days	GCACGATCTGATGCCCGGCGGGG	YAP1	ENSG00000137693	-2.187437446275826	[1076]	[99,86,NaN]	-9	hSpCas9	negative selection	9869203
102111003	102111026	11	+	27869803	PATU8988S	viability after 31 days	ATCAGATCGTGCACGTCCGCGGG	YAP1	ENSG00000137693	-2.2702292328631595	[691]	[54,59,NaN]	-9	hSpCas9	negative selection	9869204
102111157	102111180	11	-	27869803	PATU8988S	viability after 31 days	ACGAGGTTACCTGTCGGGAGTGG	YAP1	ENSG00000137693	-1.5168175877556251	[392]	[63,42,NaN]	-8	hSpCas9	negative selection	9869205
102162497	102162520	11	-	27869803	PATU8988S	viability after 31 days	GACGTTCATCTGGGACAGCATGG	YAP1	ENSG00000137693	-1.2963117033741975	[507]	[63,105,NaN]	-8	hSpCas9	negative selection	9869206
102229724	102229747	11	-	27869803	PATU8988S	viability after 31 days	AACGGTTCTGCTGTGAGGGCAGG	YAP1	ENSG00000137693	0.8239203811763128	[175]	[81,177,NaN]	8	hSpCas9	negative selection	9869207
102110992	102111015	11	-	27869803	HPAFII	viability after 35 days	GCACGATCTGATGCCCGGCGGGG	YAP1	ENSG00000137693	-1.7445100868493293	[455]	[90,43,NaN]	-7	hSpCas9	negative selection	9951652
102111003	102111026	11	+	27869803	HPAFII	viability after 35 days	ATCAGATCGTGCACGTCCGCGGG	YAP1	ENSG00000137693	-1.1971198461448573	[223]	[24,76,NaN]	-6	hSpCas9	negative selection	9951653
102111157	102111180	11	-	27869803	HPAFII	viability after 35 days	ACGAGGTTACCTGTCGGGAGTGG	YAP1	ENSG00000137693	-0.4921935114071391	[241]	[48,129,NaN]	-3	hSpCas9	negative selection	9951654
102162497	102162520	11	-	27869803	HPAFII	viability after 35 days	GACGTTCATCTGGGACAGCATGG	YAP1	ENSG00000137693	-2.0205815402097227	[232]	[53,0,NaN]	-7	hSpCas9	negative selection	9951655
102229724	102229747	11	-	27869803	HPAFII	viability after 35 days	AACGGTTCTGCTGTGAGGGCAGG	YAP1	ENSG00000137693	-1.1797856238730489	[94]	[8,34,NaN]	-6	hSpCas9	negative selection	9951656
102110992	102111015	11	-	27869803	HPAFII	viability after 31 days	GCACGATCTGATGCCCGGCGGGG	YAP1	ENSG00000137693	-1.8238801618527778	[455]	[100,40,NaN]	-8	hSpCas9	negative selection	10034101
102111003	102111026	11	+	27869803	HPAFII	viability after 31 days	ATCAGATCGTGCACGTCCGCGGG	YAP1	ENSG00000137693	-1.4940880011853335	[223]	[13,77,NaN]	-7	hSpCas9	negative selection	10034102
102111157	102111180	11	-	27869803	HPAFII	viability after 31 days	ACGAGGTTACCTGTCGGGAGTGG	YAP1	ENSG00000137693	-1.0694797196107058	[241]	[35,95,NaN]	-6	hSpCas9	negative selection	10034103
102162497	102162520	11	-	27869803	HPAFII	viability after 31 days	GACGTTCATCTGGGACAGCATGG	YAP1	ENSG00000137693	-2.0005419338652217	[232]	[58,3,NaN]	-8	hSpCas9	negative selection	10034104
102229724	102229747	11	-	27869803	HPAFII	viability after 31 days	AACGGTTCTGCTGTGAGGGCAGG	YAP1	ENSG00000137693	-0.6139891685647891	[94]	[19,50,NaN]	-4	hSpCas9	negative selection	10034105
102205946	102205969	11	+	28162770	P31FUJ	viability	GCTCCCCAGAGCCCACAGGGAGG	YAP1	ENSG00000137693	-2.823098149438575	[270]	[44]	-9	hSpCas9	negative selection	10266441
102223646	102223669	11	+	28162770	P31FUJ	viability	CCAACACTGGAGCAGGATGGTGG	YAP1	ENSG00000137693	0.1490684309292658	[65]	[85]	1	hSpCas9	negative selection	10266442
102206014	102206037	11	+	28162770	P31FUJ	viability	GCAGCAACTGCAGATGGAGAAGG	YAP1	ENSG00000137693	-1.0170735133589415	[30]	[17]	-6	hSpCas9	negative selection	10266443
102162458	102162481	11	+	28162770	P31FUJ	viability	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	0.26969813611480475	[11]	[16]	3	hSpCas9	negative selection	10266444
102205958	102205981	11	-	28162770	P31FUJ	viability	CCACCCATGACGCCTCCCTGTGG	YAP1	ENSG00000137693	0.5706182549469236	[576]	[1006]	6	hSpCas9	negative selection	10266445
102162486	102162509	11	-	28162770	P31FUJ	viability	GGGACAGCATGGCCTTCCTGGGG	YAP1	ENSG00000137693	0.45460756527759516	[76]	[123]	5	hSpCas9	negative selection	10266446
102206025	102206048	11	+	28162770	P31FUJ	viability	AGATGGAGAAGGAGAGGCTGCGG	YAP1	ENSG00000137693	-2.9432955872193935	[287]	[43]	-9	hSpCas9	negative selection	10266447
102223630	102223653	11	-	28162770	P31FUJ	viability	GTGTTGGTAACTGGCTACGCAGG	YAP1	ENSG00000137693	0.6658370806263805	[338]	[631]	7	hSpCas9	negative selection	10266448
102205993	102206016	11	-	28162770	P31FUJ	viability	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	1.0086183883133526	[268]	[635]	9	hSpCas9	negative selection	10266449
102206053	102206076	11	+	28162770	P31FUJ	viability	ACAGCAAGAACTGCTTCGGCAGG	YAP1	ENSG00000137693	0.27468154362906017	[101]	[144]	3	hSpCas9	negative selection	10266450
102205946	102205969	11	+	28162770	TF1	viability	GCTCCCCAGAGCCCACAGGGAGG	YAP1	ENSG00000137693	NaN	[NaN]	[62]	1	hSpCas9	negative selection	10435807
102223646	102223669	11	+	28162770	TF1	viability	CCAACACTGGAGCAGGATGGTGG	YAP1	ENSG00000137693	NaN	[NaN]	[91]	1	hSpCas9	negative selection	10435808
102206014	102206037	11	+	28162770	TF1	viability	GCAGCAACTGCAGATGGAGAAGG	YAP1	ENSG00000137693	NaN	[NaN]	[17]	1	hSpCas9	negative selection	10435809
102162458	102162481	11	+	28162770	TF1	viability	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	NaN	[NaN]	[7]	1	hSpCas9	negative selection	10435810
102205958	102205981	11	-	28162770	TF1	viability	CCACCCATGACGCCTCCCTGTGG	YAP1	ENSG00000137693	NaN	[NaN]	[523]	1	hSpCas9	negative selection	10435811
102162486	102162509	11	-	28162770	TF1	viability	GGGACAGCATGGCCTTCCTGGGG	YAP1	ENSG00000137693	NaN	[NaN]	[45]	1	hSpCas9	negative selection	10435812
102206025	102206048	11	+	28162770	TF1	viability	AGATGGAGAAGGAGAGGCTGCGG	YAP1	ENSG00000137693	NaN	[NaN]	[107]	1	hSpCas9	negative selection	10435813
102223630	102223653	11	-	28162770	TF1	viability	GTGTTGGTAACTGGCTACGCAGG	YAP1	ENSG00000137693	NaN	[NaN]	[472]	1	hSpCas9	negative selection	10435814
102205993	102206016	11	-	28162770	TF1	viability	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	NaN	[NaN]	[526]	1	hSpCas9	negative selection	10435815
102206053	102206076	11	+	28162770	TF1	viability	ACAGCAAGAACTGCTTCGGCAGG	YAP1	ENSG00000137693	NaN	[NaN]	[150]	1	hSpCas9	negative selection	10435816
102205946	102205969	11	+	28162770	SKM1	viability	GCTCCCCAGAGCCCACAGGGAGG	YAP1	ENSG00000137693	-1.7264240380397746	[72]	[38]	-8	hSpCas9	negative selection	10605173
102223646	102223669	11	+	28162770	SKM1	viability	CCAACACTGGAGCAGGATGGTGG	YAP1	ENSG00000137693	0.9485164558552274	[16]	[57]	8	hSpCas9	negative selection	10605174
102206014	102206037	11	+	28162770	SKM1	viability	GCAGCAACTGCAGATGGAGAAGG	YAP1	ENSG00000137693	0.8409633147004237	[17]	[56]	7	hSpCas9	negative selection	10605175
102162458	102162481	11	+	28162770	SKM1	viability	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	-0.8220016980220053	[3]	[3]	-6	hSpCas9	negative selection	10605176
102205958	102205981	11	-	28162770	SKM1	viability	CCACCCATGACGCCTCCCTGTGG	YAP1	ENSG00000137693	0.14804507987636661	[145]	[285]	1	hSpCas9	negative selection	10605177
102162486	102162509	11	-	28162770	SKM1	viability	GGGACAGCATGGCCTTCCTGGGG	YAP1	ENSG00000137693	-1.4594316186372973	[27]	[17]	-7	hSpCas9	negative selection	10605178
102206025	102206048	11	+	28162770	SKM1	viability	AGATGGAGAAGGAGAGGCTGCGG	YAP1	ENSG00000137693	-0.8960022794657823	[59]	[56]	-6	hSpCas9	negative selection	10605179
102223630	102223653	11	-	28162770	SKM1	viability	GTGTTGGTAACTGGCTACGCAGG	YAP1	ENSG00000137693	0.5986603504507165	[95]	[256]	6	hSpCas9	negative selection	10605180
102205993	102206016	11	-	28162770	SKM1	viability	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	0.5779289088666297	[71]	[189]	5	hSpCas9	negative selection	10605181
102206053	102206076	11	+	28162770	SKM1	viability	ACAGCAAGAACTGCTTCGGCAGG	YAP1	ENSG00000137693	-0.5265458144958344	[21]	[26]	-4	hSpCas9	negative selection	10605182
102205946	102205969	11	+	28162770	SKM1	viability	GCTCCCCAGAGCCCACAGGGAGG	YAP1	ENSG00000137693	-1.7264240380397746	[72]	[38]	-8	hSpCas9	negative selection	10774539
102223646	102223669	11	+	28162770	SKM1	viability	CCAACACTGGAGCAGGATGGTGG	YAP1	ENSG00000137693	0.9485164558552274	[16]	[57]	8	hSpCas9	negative selection	10774540
102206014	102206037	11	+	28162770	SKM1	viability	GCAGCAACTGCAGATGGAGAAGG	YAP1	ENSG00000137693	0.8409633147004237	[17]	[56]	7	hSpCas9	negative selection	10774541
102162458	102162481	11	+	28162770	SKM1	viability	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	-0.8220016980220053	[3]	[3]	-6	hSpCas9	negative selection	10774542
102205958	102205981	11	-	28162770	SKM1	viability	CCACCCATGACGCCTCCCTGTGG	YAP1	ENSG00000137693	0.14804507987636661	[145]	[285]	1	hSpCas9	negative selection	10774543
102162486	102162509	11	-	28162770	SKM1	viability	GGGACAGCATGGCCTTCCTGGGG	YAP1	ENSG00000137693	-1.4594316186372973	[27]	[17]	-7	hSpCas9	negative selection	10774544
102206025	102206048	11	+	28162770	SKM1	viability	AGATGGAGAAGGAGAGGCTGCGG	YAP1	ENSG00000137693	-0.8960022794657823	[59]	[56]	-6	hSpCas9	negative selection	10774545
102223630	102223653	11	-	28162770	SKM1	viability	GTGTTGGTAACTGGCTACGCAGG	YAP1	ENSG00000137693	0.5986603504507165	[95]	[256]	6	hSpCas9	negative selection	10774546
102205993	102206016	11	-	28162770	SKM1	viability	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	0.5779289088666297	[71]	[189]	5	hSpCas9	negative selection	10774547
102206053	102206076	11	+	28162770	SKM1	viability	ACAGCAAGAACTGCTTCGGCAGG	YAP1	ENSG00000137693	-0.5265458144958344	[21]	[26]	-4	hSpCas9	negative selection	10774548
102205946	102205969	11	+	28162770	PL21	viability	GCTCCCCAGAGCCCACAGGGAGG	YAP1	ENSG00000137693	-1.3981197088452941	[217]	[35]	-7	hSpCas9	negative selection	10943905
102223646	102223669	11	+	28162770	PL21	viability	CCAACACTGGAGCAGGATGGTGG	YAP1	ENSG00000137693	-1.0128541088448781	[50]	[10]	-6	hSpCas9	negative selection	10943906
102206014	102206037	11	+	28162770	PL21	viability	GCAGCAACTGCAGATGGAGAAGG	YAP1	ENSG00000137693	0.2642699519090361	[43]	[22]	2	hSpCas9	negative selection	10943907
102162458	102162481	11	+	28162770	PL21	viability	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	-1.6072153075682847	[20]	[2]	-8	hSpCas9	negative selection	10943908
102205958	102205981	11	-	28162770	PL21	viability	CCACCCATGACGCCTCCCTGTGG	YAP1	ENSG00000137693	-0.2834208540236227	[617]	[220]	-2	hSpCas9	negative selection	10943909
102162486	102162509	11	-	28162770	PL21	viability	GGGACAGCATGGCCTTCCTGGGG	YAP1	ENSG00000137693	-1.937363909260615	[87]	[9]	-8	hSpCas9	negative selection	10943910
102206025	102206048	11	+	28162770	PL21	viability	AGATGGAGAAGGAGAGGCTGCGG	YAP1	ENSG00000137693	-2.171419248122643	[206]	[19]	-8	hSpCas9	negative selection	10943911
102223630	102223653	11	-	28162770	PL21	viability	GTGTTGGTAACTGGCTACGCAGG	YAP1	ENSG00000137693	0.8246304793971138	[287]	[221]	7	hSpCas9	negative selection	10943912
102205993	102206016	11	-	28162770	PL21	viability	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	0.3521427079343703	[224]	[124]	3	hSpCas9	negative selection	10943913
102206053	102206076	11	+	28162770	PL21	viability	ACAGCAAGAACTGCTTCGGCAGG	YAP1	ENSG00000137693	-2.0975409341513647	[58]	[5]	-8	hSpCas9	negative selection	10943914
102205946	102205969	11	+	28162770	P31FUJ	viability	GCTCCCCAGAGCCCACAGGGAGG	YAP1	ENSG00000137693	-2.823098149438575	[270]	[44]	-9	hSpCas9	negative selection	11113271
102223646	102223669	11	+	28162770	P31FUJ	viability	CCAACACTGGAGCAGGATGGTGG	YAP1	ENSG00000137693	0.1490684309292658	[65]	[85]	1	hSpCas9	negative selection	11113272
102206014	102206037	11	+	28162770	P31FUJ	viability	GCAGCAACTGCAGATGGAGAAGG	YAP1	ENSG00000137693	-1.0170735133589415	[30]	[17]	-6	hSpCas9	negative selection	11113273
102162458	102162481	11	+	28162770	P31FUJ	viability	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	0.26969813611480475	[11]	[16]	3	hSpCas9	negative selection	11113274
102205958	102205981	11	-	28162770	P31FUJ	viability	CCACCCATGACGCCTCCCTGTGG	YAP1	ENSG00000137693	0.5706182549469236	[576]	[1006]	6	hSpCas9	negative selection	11113275
102162486	102162509	11	-	28162770	P31FUJ	viability	GGGACAGCATGGCCTTCCTGGGG	YAP1	ENSG00000137693	0.45460756527759516	[76]	[123]	5	hSpCas9	negative selection	11113276
102206025	102206048	11	+	28162770	P31FUJ	viability	AGATGGAGAAGGAGAGGCTGCGG	YAP1	ENSG00000137693	-2.9432955872193935	[287]	[43]	-9	hSpCas9	negative selection	11113277
102223630	102223653	11	-	28162770	P31FUJ	viability	GTGTTGGTAACTGGCTACGCAGG	YAP1	ENSG00000137693	0.6658370806263805	[338]	[631]	7	hSpCas9	negative selection	11113278
102205993	102206016	11	-	28162770	P31FUJ	viability	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	1.0086183883133526	[268]	[635]	9	hSpCas9	negative selection	11113279
102206053	102206076	11	+	28162770	P31FUJ	viability	ACAGCAAGAACTGCTTCGGCAGG	YAP1	ENSG00000137693	0.27468154362906017	[101]	[144]	3	hSpCas9	negative selection	11113280
102205946	102205969	11	+	28162770	OCIAML5	viability	GCTCCCCAGAGCCCACAGGGAGG	YAP1	ENSG00000137693	-2.0392695637381446	[188]	[82]	-8	hSpCas9	negative selection	11282637
102223646	102223669	11	+	28162770	OCIAML5	viability	CCAACACTGGAGCAGGATGGTGG	YAP1	ENSG00000137693	0.29568704957969516	[50]	[112]	2	hSpCas9	negative selection	11282638
102206014	102206037	11	+	28162770	OCIAML5	viability	GCAGCAACTGCAGATGGAGAAGG	YAP1	ENSG00000137693	-0.6456156933965707	[25]	[29]	-4	hSpCas9	negative selection	11282639
102162458	102162481	11	+	28162770	OCIAML5	viability	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	-3.4370290715851537	[5]	[0]	-9	hSpCas9	negative selection	11282640
102205958	102205981	11	-	28162770	OCIAML5	viability	CCACCCATGACGCCTCCCTGTGG	YAP1	ENSG00000137693	0.5996293989936952	[237]	[650]	5	hSpCas9	negative selection	11282641
102162486	102162509	11	-	28162770	OCIAML5	viability	GGGACAGCATGGCCTTCCTGGGG	YAP1	ENSG00000137693	1.0266271329138692	[30]	[113]	8	hSpCas9	negative selection	11282642
102206025	102206048	11	+	28162770	OCIAML5	viability	AGATGGAGAAGGAGAGGCTGCGG	YAP1	ENSG00000137693	-1.7160050212879687	[181]	[99]	-7	hSpCas9	negative selection	11282643
102223630	102223653	11	-	28162770	OCIAML5	viability	GTGTTGGTAACTGGCTACGCAGG	YAP1	ENSG00000137693	0.4035883046041995	[195]	[467]	3	hSpCas9	negative selection	11282644
102205993	102206016	11	-	28162770	OCIAML5	viability	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	0.5431624473346667	[164]	[433]	5	hSpCas9	negative selection	11282645
102206053	102206076	11	+	28162770	OCIAML5	viability	ACAGCAAGAACTGCTTCGGCAGG	YAP1	ENSG00000137693	0.5180450575333303	[52]	[136]	4	hSpCas9	negative selection	11282646
102205946	102205969	11	+	28162770	EOL1	viability	GCTCCCCAGAGCCCACAGGGAGG	YAP1	ENSG00000137693	-0.20603633823960976	[415]	[189]	-1	hSpCas9	negative selection	11452003
102223646	102223669	11	+	28162770	EOL1	viability	CCAACACTGGAGCAGGATGGTGG	YAP1	ENSG00000137693	-2.126078301499433	[115]	[13]	-8	hSpCas9	negative selection	11452004
102206014	102206037	11	+	28162770	EOL1	viability	GCAGCAACTGCAGATGGAGAAGG	YAP1	ENSG00000137693	0.0231116060541241	[98]	[52]	0	hSpCas9	negative selection	11452005
102162458	102162481	11	+	28162770	EOL1	viability	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	0.9703514611836592	[30]	[31]	8	hSpCas9	negative selection	11452006
102205958	102205981	11	-	28162770	EOL1	viability	CCACCCATGACGCCTCCCTGTGG	YAP1	ENSG00000137693	-0.21593345197929592	[969]	[439]	-2	hSpCas9	negative selection	11452007
102162486	102162509	11	-	28162770	EOL1	viability	GGGACAGCATGGCCTTCCTGGGG	YAP1	ENSG00000137693	-0.12354651663051053	[121]	[58]	-1	hSpCas9	negative selection	11452008
102206025	102206048	11	+	28162770	EOL1	viability	AGATGGAGAAGGAGAGGCTGCGG	YAP1	ENSG00000137693	-1.6373311160375805	[247]	[41]	-7	hSpCas9	negative selection	11452009
102223630	102223653	11	-	28162770	EOL1	viability	GTGTTGGTAACTGGCTACGCAGG	YAP1	ENSG00000137693	0.6054420350157568	[382]	[306]	5	hSpCas9	negative selection	11452010
102205993	102206016	11	-	28162770	EOL1	viability	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	0.11923488105114907	[352]	[201]	1	hSpCas9	negative selection	11452011
102206053	102206076	11	+	28162770	EOL1	viability	ACAGCAAGAACTGCTTCGGCAGG	YAP1	ENSG00000137693	0.5039720887502608	[86]	[64]	4	hSpCas9	negative selection	11452012
102205946	102205969	11	+	28162770	MOLM13	viability	GCTCCCCAGAGCCCACAGGGAGG	YAP1	ENSG00000137693	-2.8958588890374104	[349]	[33]	-8	hSpCas9	negative selection	11621369
102223646	102223669	11	+	28162770	MOLM13	viability	CCAACACTGGAGCAGGATGGTGG	YAP1	ENSG00000137693	0.8775336220532042	[66]	[88]	6	hSpCas9	negative selection	11621370
102206014	102206037	11	+	28162770	MOLM13	viability	GCAGCAACTGCAGATGGAGAAGG	YAP1	ENSG00000137693	-0.9706836321950538	[102]	[37]	-5	hSpCas9	negative selection	11621371
102162458	102162481	11	+	28162770	MOLM13	viability	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	-0.7545030397918686	[27]	[11]	-4	hSpCas9	negative selection	11621372
102205958	102205981	11	-	28162770	MOLM13	viability	CCACCCATGACGCCTCCCTGTGG	YAP1	ENSG00000137693	0.3909273997296947	[769]	[729]	3	hSpCas9	negative selection	11621373
102162486	102162509	11	-	28162770	MOLM13	viability	GGGACAGCATGGCCTTCCTGGGG	YAP1	ENSG00000137693	1.1523875558166496	[83]	[134]	8	hSpCas9	negative selection	11621374
102206025	102206048	11	+	28162770	MOLM13	viability	AGATGGAGAAGGAGAGGCTGCGG	YAP1	ENSG00000137693	-1.7668867642477015	[272]	[57]	-7	hSpCas9	negative selection	11621375
102223630	102223653	11	-	28162770	MOLM13	viability	GTGTTGGTAACTGGCTACGCAGG	YAP1	ENSG00000137693	0.8158126849648856	[285]	[363]	6	hSpCas9	negative selection	11621376
102205993	102206016	11	-	28162770	MOLM13	viability	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	0.03030931361464667	[343]	[253]	0	hSpCas9	negative selection	11621377
102206053	102206076	11	+	28162770	MOLM13	viability	ACAGCAAGAACTGCTTCGGCAGG	YAP1	ENSG00000137693	-2.2509288659113675	[78]	[11]	-7	hSpCas9	negative selection	11621378
102205946	102205969	11	+	28162770	HEL	viability	GCTCCCCAGAGCCCACAGGGAGG	YAP1	ENSG00000137693	-1.9317312949031569	[273]	[45]	-7	hSpCas9	negative selection	11790735
102223646	102223669	11	+	28162770	HEL	viability	CCAACACTGGAGCAGGATGGTGG	YAP1	ENSG00000137693	0.8990785852601424	[35]	[42]	7	hSpCas9	negative selection	11790736
102206014	102206037	11	+	28162770	HEL	viability	GCAGCAACTGCAGATGGAGAAGG	YAP1	ENSG00000137693	-0.06352996494293262	[92]	[56]	0	hSpCas9	negative selection	11790737
102162458	102162481	11	+	28162770	HEL	viability	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	1.7947419254454067	[17]	[39]	9	hSpCas9	negative selection	11790738
102205958	102205981	11	-	28162770	HEL	viability	CCACCCATGACGCCTCCCTGTGG	YAP1	ENSG00000137693	0.8925278170463617	[692]	[823]	7	hSpCas9	negative selection	11790739
102162486	102162509	11	-	28162770	HEL	viability	GGGACAGCATGGCCTTCCTGGGG	YAP1	ENSG00000137693	-1.6467677851946276	[87]	[17]	-7	hSpCas9	negative selection	11790740
102206025	102206048	11	+	28162770	HEL	viability	AGATGGAGAAGGAGAGGCTGCGG	YAP1	ENSG00000137693	-0.39120849992298085	[214]	[104]	-3	hSpCas9	negative selection	11790741
102223630	102223653	11	-	28162770	HEL	viability	GTGTTGGTAACTGGCTACGCAGG	YAP1	ENSG00000137693	0.6427388320003568	[258]	[258]	5	hSpCas9	negative selection	11790742
102205993	102206016	11	-	28162770	HEL	viability	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	0.6575865964076704	[289]	[292]	5	hSpCas9	negative selection	11790743
102206053	102206076	11	+	28162770	HEL	viability	ACAGCAAGAACTGCTTCGGCAGG	YAP1	ENSG00000137693	0.2707700546133991	[87]	[67]	2	hSpCas9	negative selection	11790744
102205946	102205969	11	+	28162770	MV411	viability	GCTCCCCAGAGCCCACAGGGAGG	YAP1	ENSG00000137693	-2.4275571508008533	[280]	[43]	-8	hSpCas9	negative selection	11960101
102223646	102223669	11	+	28162770	MV411	viability	CCAACACTGGAGCAGGATGGTGG	YAP1	ENSG00000137693	-0.3950104445991409	[63]	[40]	-3	hSpCas9	negative selection	11960102
102206014	102206037	11	+	28162770	MV411	viability	GCAGCAACTGCAGATGGAGAAGG	YAP1	ENSG00000137693	0.15432814639129377	[63]	[59]	1	hSpCas9	negative selection	11960103
102162458	102162481	11	+	28162770	MV411	viability	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	0.3629147682027112	[11]	[12]	3	hSpCas9	negative selection	11960104
102205958	102205981	11	-	28162770	MV411	viability	CCACCCATGACGCCTCCCTGTGG	YAP1	ENSG00000137693	-0.1262591531151691	[687]	[530]	-1	hSpCas9	negative selection	11960105
102162486	102162509	11	-	28162770	MV411	viability	GGGACAGCATGGCCTTCCTGGGG	YAP1	ENSG00000137693	0.6810907282289661	[76]	[103]	6	hSpCas9	negative selection	11960106
102206025	102206048	11	+	28162770	MV411	viability	AGATGGAGAAGGAGAGGCTGCGG	YAP1	ENSG00000137693	-1.5599173712748287	[209]	[59]	-7	hSpCas9	negative selection	11960107
102223630	102223653	11	-	28162770	MV411	viability	GTGTTGGTAACTGGCTACGCAGG	YAP1	ENSG00000137693	0.7154239300105781	[213]	[295]	6	hSpCas9	negative selection	11960108
102205993	102206016	11	-	28162770	MV411	viability	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	1.1428716309562923	[235]	[438]	8	hSpCas9	negative selection	11960109
102206053	102206076	11	+	28162770	MV411	viability	ACAGCAAGAACTGCTTCGGCAGG	YAP1	ENSG00000137693	1.0015273227401904	[66]	[112]	8	hSpCas9	negative selection	11960110
102205946	102205969	11	+	28162770	MONOMAC1	viability	GCTCCCCAGAGCCCACAGGGAGG	YAP1	ENSG00000137693	-0.9981327786454753	[114]	[65]	-7	hSpCas9	negative selection	12129467
102223646	102223669	11	+	28162770	MONOMAC1	viability	CCAACACTGGAGCAGGATGGTGG	YAP1	ENSG00000137693	0.7452476550841589	[50]	[97]	7	hSpCas9	negative selection	12129468
102206014	102206037	11	+	28162770	MONOMAC1	viability	GCAGCAACTGCAGATGGAGAAGG	YAP1	ENSG00000137693	-0.30013034002365746	[28]	[26]	-3	hSpCas9	negative selection	12129469
102162458	102162481	11	+	28162770	MONOMAC1	viability	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	1.842491517127084	[8]	[36]	9	hSpCas9	negative selection	12129470
102205958	102205981	11	-	28162770	MONOMAC1	viability	CCACCCATGACGCCTCCCTGTGG	YAP1	ENSG00000137693	0.6872800568129345	[291]	[538]	6	hSpCas9	negative selection	12129471
102162486	102162509	11	-	28162770	MONOMAC1	viability	GGGACAGCATGGCCTTCCTGGGG	YAP1	ENSG00000137693	3.4600754394174382	[38]	[491]	9	hSpCas9	negative selection	12129472
102206025	102206048	11	+	28162770	MONOMAC1	viability	AGATGGAGAAGGAGAGGCTGCGG	YAP1	ENSG00000137693	-1.1970368470595536	[123]	[61]	-7	hSpCas9	negative selection	12129473
102223630	102223653	11	-	28162770	MONOMAC1	viability	GTGTTGGTAACTGGCTACGCAGG	YAP1	ENSG00000137693	0.7841041256891306	[153]	[303]	7	hSpCas9	negative selection	12129474
102205993	102206016	11	-	28162770	MONOMAC1	viability	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	1.8976000270785214	[117]	[503]	9	hSpCas9	negative selection	12129475
102206053	102206076	11	+	28162770	MONOMAC1	viability	ACAGCAAGAACTGCTTCGGCAGG	YAP1	ENSG00000137693	0.5726655335186521	[60]	[103]	5	hSpCas9	negative selection	12129476
102205946	102205969	11	+	28162770	OCIAML2	viability	GCTCCCCAGAGCCCACAGGGAGG	YAP1	ENSG00000137693	-1.2296217257383664	[43]	[103]	-7	hSpCas9	negative selection	12298833
102223646	102223669	11	+	28162770	OCIAML2	viability	CCAACACTGGAGCAGGATGGTGG	YAP1	ENSG00000137693	1.1616383902573517	[9]	[123]	9	hSpCas9	negative selection	12298834
102206014	102206037	11	+	28162770	OCIAML2	viability	GCAGCAACTGCAGATGGAGAAGG	YAP1	ENSG00000137693	1.073690690981649	[5]	[69]	8	hSpCas9	negative selection	12298835
102162458	102162481	11	+	28162770	OCIAML2	viability	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	-1.4706298252421615	[2]	[5]	-7	hSpCas9	negative selection	12298836
102205958	102205981	11	-	28162770	OCIAML2	viability	CCACCCATGACGCCTCCCTGTGG	YAP1	ENSG00000137693	0.6260280442083122	[91]	[786]	6	hSpCas9	negative selection	12298837
102162486	102162509	11	-	28162770	OCIAML2	viability	GGGACAGCATGGCCTTCCTGGGG	YAP1	ENSG00000137693	-1.470629825242161	[14]	[29]	-7	hSpCas9	negative selection	12298838
102206025	102206048	11	+	28162770	OCIAML2	viability	AGATGGAGAAGGAGAGGCTGCGG	YAP1	ENSG00000137693	-2.4706298252421615	[34]	[34]	-8	hSpCas9	negative selection	12298839
102223630	102223653	11	-	28162770	OCIAML2	viability	GTGTTGGTAACTGGCTACGCAGG	YAP1	ENSG00000137693	1.3571891993751584	[39]	[567]	9	hSpCas9	negative selection	12298840
102205993	102206016	11	-	28162770	OCIAML2	viability	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	0.592696110126668	[38]	[325]	6	hSpCas9	negative selection	12298841
102206053	102206076	11	+	28162770	OCIAML2	viability	ACAGCAAGAACTGCTTCGGCAGG	YAP1	ENSG00000137693	0.7077074160163512	[18]	[171]	7	hSpCas9	negative selection	12298842
102205946	102205969	11	+	28162770	OCIAML3	viability	GCTCCCCAGAGCCCACAGGGAGG	YAP1	ENSG00000137693	-0.4289483940536667	[65]	[147]	-3	hSpCas9	negative selection	12468199
102223646	102223669	11	+	28162770	OCIAML3	viability	CCAACACTGGAGCAGGATGGTGG	YAP1	ENSG00000137693	0.24249362739295743	[27]	[99]	2	hSpCas9	negative selection	12468200
102206014	102206037	11	+	28162770	OCIAML3	viability	GCAGCAACTGCAGATGGAGAAGG	YAP1	ENSG00000137693	1.6454582943712266	[8]	[84]	9	hSpCas9	negative selection	12468201
102162458	102162481	11	+	28162770	OCIAML3	viability	ACATCGATCAGACAACAACATGG	YAP1	ENSG00000137693	-0.231437560939455	[6]	[17]	-2	hSpCas9	negative selection	12468202
102205958	102205981	11	-	28162770	OCIAML3	viability	CCACCCATGACGCCTCCCTGTGG	YAP1	ENSG00000137693	0.26069280652686366	[166]	[603]	2	hSpCas9	negative selection	12468203
102162486	102162509	11	-	28162770	OCIAML3	viability	GGGACAGCATGGCCTTCCTGGGG	YAP1	ENSG00000137693	-2.417129878240084	[22]	[12]	-9	hSpCas9	negative selection	12468204
102206025	102206048	11	+	28162770	OCIAML3	viability	AGATGGAGAAGGAGAGGCTGCGG	YAP1	ENSG00000137693	-1.460741109460699	[61]	[67]	-7	hSpCas9	negative selection	12468205
102223630	102223653	11	-	28162770	OCIAML3	viability	GTGTTGGTAACTGGCTACGCAGG	YAP1	ENSG00000137693	0.24519614777278081	[63]	[228]	2	hSpCas9	negative selection	12468206
102205993	102206016	11	-	28162770	OCIAML3	viability	GCAGTCGCATCTGTTGCTGCTGG	YAP1	ENSG00000137693	0.2072727673237565	[67]	[236]	2	hSpCas9	negative selection	12468207
102206053	102206076	11	+	28162770	OCIAML3	viability	ACAGCAAGAACTGCTTCGGCAGG	YAP1	ENSG00000137693	0.32798984767456374	[18]	[71]	3	hSpCas9	negative selection	12468208