Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 2314
• Symbol: fliI
• Description: FLII actin remodeling protein

DataSource: http://genomecrispr.dkfz.de/#!/results/fliI

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
18247291	18247314	17	-	26472758	Jiyoye	viability	GGACTACACACGCAATGCGGAGG	FLII	ENSG00000177731	0.025541040494243328	[184]	[141]	0	hSpCas9	negative selection	58537
18247689	18247712	17	-	26472758	Jiyoye	viability	GCACCGGCCACGCCATGCCACGG	FLII	ENSG00000177731	-0.09032427796494336	[119]	[84]	0	hSpCas9	negative selection	58538
18246800	18246823	17	-	26472758	Jiyoye	viability	GGTGCCTGTGGAGTACGAGGAGG	FLII	ENSG00000177731	-0.7854696964365223	[143]	[62]	-5	hSpCas9	negative selection	58539
18251433	18251456	17	+	26472758	Jiyoye	viability	CCAACGCCGCACCTTCCCGCTGG	FLII	ENSG00000177731	-0.3628190130478035	[161]	[94]	-3	hSpCas9	negative selection	58540
18251381	18251404	17	-	26472758	Jiyoye	viability	CTACTCCGAGTTCTTCACGGAGG	FLII	ENSG00000177731	0.9885712672068372	[134]	[201]	6	hSpCas9	negative selection	58541
18251285	18251308	17	+	26472758	Jiyoye	viability	CAGCCTCGTAGAACTTGCCGTGG	FLII	ENSG00000177731	0.46606907055944186	[95]	[99]	3	hSpCas9	negative selection	58542
18250870	18250893	17	-	26472758	Jiyoye	viability	TGAGTGCCGCACTGTCCGGGAGG	FLII	ENSG00000177731	-0.4341268724750684	[42]	[23]	-3	hSpCas9	negative selection	58543
18249362	18249385	17	-	26472758	Jiyoye	viability	ATTGAGGGTGGAACAGCCAGTGG	FLII	ENSG00000177731	0.20554152033622303	[137]	[119]	1	hSpCas9	negative selection	58544
18248627	18248650	17	-	26472758	Jiyoye	viability	GGAGCTCCCAGAGTTCTGGGAGG	FLII	ENSG00000177731	-0.5773945779245204	[92]	[46]	-4	hSpCas9	negative selection	58545
18248617	18248640	17	-	26472758	Jiyoye	viability	GAGTTCTGGGAGGCACTGGGTGG	FLII	ENSG00000177731	3.5771003829481853	[1]	[17]	9	hSpCas9	negative selection	58546
18247291	18247314	17	-	26472758	KBM7	viability	GGACTACACACGCAATGCGGAGG	FLII	ENSG00000177731	-2.0077995274303353	[812,599]	[67,93]	-8	hSpCas9	negative selection	249655
18247689	18247712	17	-	26472758	KBM7	viability	GCACCGGCCACGCCATGCCACGG	FLII	ENSG00000177731	-2.051326547802521	[572,682]	[67,75]	-8	hSpCas9	negative selection	249656
18246800	18246823	17	-	26472758	KBM7	viability	GGTGCCTGTGGAGTACGAGGAGG	FLII	ENSG00000177731	-1.4065309704342728	[570,353]	[33,121]	-7	hSpCas9	negative selection	249657
18251433	18251456	17	+	26472758	KBM7	viability	CCAACGCCGCACCTTCCCGCTGG	FLII	ENSG00000177731	0.3496533176115657	[409,339]	[343,115]	4	hSpCas9	negative selection	249658
18251381	18251404	17	-	26472758	KBM7	viability	CTACTCCGAGTTCTTCACGGAGG	FLII	ENSG00000177731	-1.6579743046710322	[724,513]	[78,101]	-8	hSpCas9	negative selection	249659
18251285	18251308	17	+	26472758	KBM7	viability	CAGCCTCGTAGAACTTGCCGTGG	FLII	ENSG00000177731	-1.6986892519555143	[177,247]	[49,14]	-8	hSpCas9	negative selection	249660
18250870	18250893	17	-	26472758	KBM7	viability	TGAGTGCCGCACTGTCCGGGAGG	FLII	ENSG00000177731	-1.9453469473970082	[280,164]	[42,11]	-8	hSpCas9	negative selection	249661
18249362	18249385	17	-	26472758	KBM7	viability	ATTGAGGGTGGAACAGCCAGTGG	FLII	ENSG00000177731	-1.180300832635238	[751,626]	[124,157]	-7	hSpCas9	negative selection	249662
18248627	18248650	17	-	26472758	KBM7	viability	GGAGCTCCCAGAGTTCTGGGAGG	FLII	ENSG00000177731	-2.1043624082511263	[207,158]	[21,17]	-8	hSpCas9	negative selection	249663
18248617	18248640	17	-	26472758	KBM7	viability	GAGTTCTGGGAGGCACTGGGTGG	FLII	ENSG00000177731	-0.6758372794224186	[105,78]	[8,42]	-5	hSpCas9	negative selection	249664
18247291	18247314	17	-	26472758	Raji	viability	GGACTACACACGCAATGCGGAGG	FLII	ENSG00000177731	-0.8401490447322648	[323]	[41]	-6	hSpCas9	negative selection	440773
18247689	18247712	17	-	26472758	Raji	viability	GCACCGGCCACGCCATGCCACGG	FLII	ENSG00000177731	0.13265029398402944	[282]	[71]	1	hSpCas9	negative selection	440774
18246800	18246823	17	-	26472758	Raji	viability	GGTGCCTGTGGAGTACGAGGAGG	FLII	ENSG00000177731	-1.5364726544011251	[224]	[17]	-8	hSpCas9	negative selection	440775
18251433	18251456	17	+	26472758	Raji	viability	CCAACGCCGCACCTTCCCGCTGG	FLII	ENSG00000177731	-0.4598769636140976	[242]	[40]	-4	hSpCas9	negative selection	440776
18251381	18251404	17	-	26472758	Raji	viability	CTACTCCGAGTTCTTCACGGAGG	FLII	ENSG00000177731	0.3215083407264468	[299]	[86]	3	hSpCas9	negative selection	440777
18251285	18251308	17	+	26472758	Raji	viability	CAGCCTCGTAGAACTTGCCGTGG	FLII	ENSG00000177731	-0.04912095030639119	[106]	[23]	0	hSpCas9	negative selection	440778
18250870	18250893	17	-	26472758	Raji	viability	TGAGTGCCGCACTGTCCGGGAGG	FLII	ENSG00000177731	0.5421842894738732	[144]	[48]	5	hSpCas9	negative selection	440779
18249362	18249385	17	-	26472758	Raji	viability	ATTGAGGGTGGAACAGCCAGTGG	FLII	ENSG00000177731	-0.41134526694747	[446]	[77]	-3	hSpCas9	negative selection	440780
18248627	18248650	17	-	26472758	Raji	viability	GGAGCTCCCAGAGTTCTGGGAGG	FLII	ENSG00000177731	0.272807144580971	[106]	[29]	2	hSpCas9	negative selection	440781
18248617	18248640	17	-	26472758	Raji	viability	GAGTTCTGGGAGGCACTGGGTGG	FLII	ENSG00000177731	0.20049293976508076	[59]	[15]	2	hSpCas9	negative selection	440782
18247291	18247314	17	-	26472758	K562	viability	GGACTACACACGCAATGCGGAGG	FLII	ENSG00000177731	-0.2410080995037948	[538]	[384]	-2	hSpCas9	negative selection	631891
18247689	18247712	17	-	26472758	K562	viability	GCACCGGCCACGCCATGCCACGG	FLII	ENSG00000177731	-1.47425571764227	[417]	[126]	-6	hSpCas9	negative selection	631892
18246800	18246823	17	-	26472758	K562	viability	GGTGCCTGTGGAGTACGAGGAGG	FLII	ENSG00000177731	-1.4717883063329618	[344]	[104]	-6	hSpCas9	negative selection	631893
18251433	18251456	17	+	26472758	K562	viability	CCAACGCCGCACCTTCCCGCTGG	FLII	ENSG00000177731	0.015284728450943585	[285]	[243]	0	hSpCas9	negative selection	631894
18251381	18251404	17	-	26472758	K562	viability	CTACTCCGAGTTCTTCACGGAGG	FLII	ENSG00000177731	-0.28351282801833044	[557]	[386]	-2	hSpCas9	negative selection	631895
18251285	18251308	17	+	26472758	K562	viability	CAGCCTCGTAGAACTTGCCGTGG	FLII	ENSG00000177731	-0.23049022758979554	[163]	[117]	-1	hSpCas9	negative selection	631896
18250870	18250893	17	-	26472758	K562	viability	TGAGTGCCGCACTGTCCGGGAGG	FLII	ENSG00000177731	-0.45819536170898245	[165]	[101]	-3	hSpCas9	negative selection	631897
18249362	18249385	17	-	26472758	K562	viability	ATTGAGGGTGGAACAGCCAGTGG	FLII	ENSG00000177731	-1.0106098421522827	[610]	[255]	-5	hSpCas9	negative selection	631898
18248627	18248650	17	-	26472758	K562	viability	GGAGCTCCCAGAGTTCTGGGAGG	FLII	ENSG00000177731	-1.669851398307669	[195]	[51]	-7	hSpCas9	negative selection	631899
18248617	18248640	17	-	26472758	K562	viability	GAGTTCTGGGAGGCACTGGGTGG	FLII	ENSG00000177731	-0.9723926614067011	[85]	[36]	-5	hSpCas9	negative selection	631900
18254606	18254629	17	-	26627737	DLD1	viability	GGACCTCAGCGAGAACCGCCTGG	FLII	ENSG00000177731	-0.06007473904270322	[93]	[61,21,3]	0	hSpCas9	negative selection	796409
18254819	18254842	17	-	26627737	DLD1	viability	ACCAGCTGACAGAGTGCCCGCGG	FLII	ENSG00000177731	0.1673274162460895	[597]	[113,308,210]	1	hSpCas9	negative selection	796410
18255240	18255263	17	+	26627737	DLD1	viability	ACTGTTGGCTCGGGCCACGATGG	FLII	ENSG00000177731	-0.44970736127629973	[570]	[114,188,95]	-4	hSpCas9	negative selection	796411
18256515	18256538	17	+	26627737	DLD1	viability	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	0.06404085660829584	[687]	[107,364,209]	0	hSpCas9	negative selection	796412
18256959	18256982	17	+	26627737	DLD1	viability	GGTTCAGCTTCAGCCACCGCAGG	FLII	ENSG00000177731	-1.9294020897493898	[574]	[56,76,13]	-8	hSpCas9	negative selection	796413
18258647	18258670	17	+	26627737	DLD1	viability	AGGTCCACGCCACGCACGAACGG	FLII	ENSG00000177731	-0.2212191959613925	[966]	[320,368,114]	-2	hSpCas9	negative selection	796414
18254606	18254629	17	-	26627737	GBM cells	viability after 5 days	GGACCTCAGCGAGAACCGCCTGG	FLII	ENSG00000177731	0.7220361128016064	[51]	[49,41]	8	hSpCas9	negative selection	878724
18254819	18254842	17	-	26627737	GBM cells	viability after 5 days	ACCAGCTGACAGAGTGCCCGCGG	FLII	ENSG00000177731	-0.30310475626648037	[374]	[185,139]	-5	hSpCas9	negative selection	878725
18255240	18255263	17	+	26627737	GBM cells	viability after 5 days	ACTGTTGGCTCGGGCCACGATGG	FLII	ENSG00000177731	-0.3490136385579	[208]	[68,106]	-5	hSpCas9	negative selection	878726
18256515	18256538	17	+	26627737	GBM cells	viability after 5 days	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	-0.27908442709230874	[447]	[181,213]	-4	hSpCas9	negative selection	878727
18256959	18256982	17	+	26627737	GBM cells	viability after 5 days	GGTTCAGCTTCAGCCACCGCAGG	FLII	ENSG00000177731	-0.901477099422154	[154]	[42,45]	-8	hSpCas9	negative selection	878728
18258647	18258670	17	+	26627737	GBM cells	viability after 5 days	AGGTCCACGCCACGCACGAACGG	FLII	ENSG00000177731	0.4065174929006023	[331]	[242,228]	6	hSpCas9	negative selection	878729
18254606	18254629	17	-	26627737	GBM cells	viability after 13 days	GGACCTCAGCGAGAACCGCCTGG	FLII	ENSG00000177731	0.11274850605866638	[51]	[8,47]	1	hSpCas9	negative selection	961039
18254819	18254842	17	-	26627737	GBM cells	viability after 13 days	ACCAGCTGACAGAGTGCCCGCGG	FLII	ENSG00000177731	-0.26538095273118595	[374]	[176,162]	-3	hSpCas9	negative selection	961040
18255240	18255263	17	+	26627737	GBM cells	viability after 13 days	ACTGTTGGCTCGGGCCACGATGG	FLII	ENSG00000177731	-0.8848128531828903	[208]	[56,64]	-7	hSpCas9	negative selection	961041
18256515	18256538	17	+	26627737	GBM cells	viability after 13 days	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	-0.41669963920771935	[447]	[164,195]	-5	hSpCas9	negative selection	961042
18256959	18256982	17	+	26627737	GBM cells	viability after 13 days	GGTTCAGCTTCAGCCACCGCAGG	FLII	ENSG00000177731	-1.4938648110218038	[154]	[25,32]	-9	hSpCas9	negative selection	961043
18258647	18258670	17	+	26627737	GBM cells	viability after 13 days	AGGTCCACGCCACGCACGAACGG	FLII	ENSG00000177731	0.034828150730832175	[331]	[226,149]	0	hSpCas9	negative selection	961044
18254606	18254629	17	-	26627737	GBM cells	viability after 21 days	GGACCTCAGCGAGAACCGCCTGG	FLII	ENSG00000177731	0.6377671959040025	[51]	[44,42]	6	hSpCas9	negative selection	1043354
18254819	18254842	17	-	26627737	GBM cells	viability after 21 days	ACCAGCTGACAGAGTGCCCGCGG	FLII	ENSG00000177731	-0.1895662468727809	[374]	[186,170]	-2	hSpCas9	negative selection	1043355
18255240	18255263	17	+	26627737	GBM cells	viability after 21 days	ACTGTTGGCTCGGGCCACGATGG	FLII	ENSG00000177731	-1.3749990144511604	[208]	[48,38]	-8	hSpCas9	negative selection	1043356
18256515	18256538	17	+	26627737	GBM cells	viability after 21 days	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	-1.137914047094601	[447]	[119,101]	-7	hSpCas9	negative selection	1043357
18256959	18256982	17	+	26627737	GBM cells	viability after 21 days	GGTTCAGCTTCAGCCACCGCAGG	FLII	ENSG00000177731	-1.900480189915715	[154]	[32,12]	-8	hSpCas9	negative selection	1043358
18258647	18258670	17	+	26627737	GBM cells	viability after 21 days	AGGTCCACGCCACGCACGAACGG	FLII	ENSG00000177731	-0.29524283826052977	[331]	[158,135]	-3	hSpCas9	negative selection	1043359
18254606	18254629	17	-	26627737	RPE1	viability after 9 days	GGACCTCAGCGAGAACCGCCTGG	FLII	ENSG00000177731	6.674493732234472	[3]	[54,221]	9	hSpCas9	negative selection	1125669
18254819	18254842	17	-	26627737	RPE1	viability after 9 days	ACCAGCTGACAGAGTGCCCGCGG	FLII	ENSG00000177731	-0.25049904685961544	[1735]	[200,786]	-2	hSpCas9	negative selection	1125670
18255240	18255263	17	+	26627737	RPE1	viability after 9 days	ACTGTTGGCTCGGGCCACGATGG	FLII	ENSG00000177731	1.8247727174889392	[271]	[226,397]	8	hSpCas9	negative selection	1125671
18256515	18256538	17	+	26627737	RPE1	viability after 9 days	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	-0.1436089904813007	[2346]	[617,725]	-1	hSpCas9	negative selection	1125672
18256959	18256982	17	+	26627737	RPE1	viability after 9 days	GGTTCAGCTTCAGCCACCGCAGG	FLII	ENSG00000177731	0.44591887645902445	[412]	[145,214]	3	hSpCas9	negative selection	1125673
18258647	18258670	17	+	26627737	RPE1	viability after 9 days	AGGTCCACGCCACGCACGAACGG	FLII	ENSG00000177731	0.390615205713965	[1051]	[343,544]	2	hSpCas9	negative selection	1125674
18254606	18254629	17	-	26627737	RPE1	viability after 12 days	GGACCTCAGCGAGAACCGCCTGG	FLII	ENSG00000177731	6.27610856281603	[3]	[41,126]	9	hSpCas9	negative selection	1207984
18254819	18254842	17	-	26627737	RPE1	viability after 12 days	ACCAGCTGACAGAGTGCCCGCGG	FLII	ENSG00000177731	0.025128469535244058	[1735]	[324,632]	0	hSpCas9	negative selection	1207985
18255240	18255263	17	+	26627737	RPE1	viability after 12 days	ACTGTTGGCTCGGGCCACGATGG	FLII	ENSG00000177731	2.0018570910753004	[271]	[247,339]	8	hSpCas9	negative selection	1207986
18256515	18256538	17	+	26627737	RPE1	viability after 12 days	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	0.139547885644697	[2346]	[850,528]	1	hSpCas9	negative selection	1207987
18256959	18256982	17	+	26627737	RPE1	viability after 12 days	GGTTCAGCTTCAGCCACCGCAGG	FLII	ENSG00000177731	0.7766197416908623	[412]	[192,186]	5	hSpCas9	negative selection	1207988
18258647	18258670	17	+	26627737	RPE1	viability after 12 days	AGGTCCACGCCACGCACGAACGG	FLII	ENSG00000177731	0.7669998074344727	[1051]	[530,427]	5	hSpCas9	negative selection	1207989
18254606	18254629	17	-	26627737	RPE1	viability after 15 days	GGACCTCAGCGAGAACCGCCTGG	FLII	ENSG00000177731	6.467627335518857	[3]	[35,161]	9	hSpCas9	negative selection	1290299
18254819	18254842	17	-	26627737	RPE1	viability after 15 days	ACCAGCTGACAGAGTGCCCGCGG	FLII	ENSG00000177731	0.27173362142456714	[1735]	[375,801]	1	hSpCas9	negative selection	1290300
18255240	18255263	17	+	26627737	RPE1	viability after 15 days	ACTGTTGGCTCGGGCCACGATGG	FLII	ENSG00000177731	2.3238227963670517	[271]	[400,369]	9	hSpCas9	negative selection	1290301
18256515	18256538	17	+	26627737	RPE1	viability after 15 days	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	0.36861422506181785	[2346]	[930,785]	2	hSpCas9	negative selection	1290302
18256959	18256982	17	+	26627737	RPE1	viability after 15 days	GGTTCAGCTTCAGCCACCGCAGG	FLII	ENSG00000177731	1.2677793014858256	[412]	[319,243]	7	hSpCas9	negative selection	1290303
18258647	18258670	17	+	26627737	RPE1	viability after 15 days	AGGTCCACGCCACGCACGAACGG	FLII	ENSG00000177731	1.108679663633803	[1051]	[824,464]	6	hSpCas9	negative selection	1290304
18254606	18254629	17	-	26627737	RPE1	viability after 18 days	GGACCTCAGCGAGAACCGCCTGG	FLII	ENSG00000177731	6.188159799751438	[3]	[11,149]	9	hSpCas9	negative selection	1372614
18254819	18254842	17	-	26627737	RPE1	viability after 18 days	ACCAGCTGACAGAGTGCCCGCGG	FLII	ENSG00000177731	0.2765032446619444	[1735]	[376,770]	1	hSpCas9	negative selection	1372615
18255240	18255263	17	+	26627737	RPE1	viability after 18 days	ACTGTTGGCTCGGGCCACGATGG	FLII	ENSG00000177731	2.597129382135333	[271]	[404,485]	9	hSpCas9	negative selection	1372616
18256515	18256538	17	+	26627737	RPE1	viability after 18 days	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	0.32618188467797427	[2346]	[795,791]	2	hSpCas9	negative selection	1372617
18256959	18256982	17	+	26627737	RPE1	viability after 18 days	GGTTCAGCTTCAGCCACCGCAGG	FLII	ENSG00000177731	1.5953211681926966	[412]	[475,187]	8	hSpCas9	negative selection	1372618
18258647	18258670	17	+	26627737	RPE1	viability after 18 days	AGGTCCACGCCACGCACGAACGG	FLII	ENSG00000177731	0.9360486602676897	[1051]	[533,552]	5	hSpCas9	negative selection	1372619
18254606	18254629	17	-	26627737	HeLa	viability after 8 days	GGACCTCAGCGAGAACCGCCTGG	FLII	ENSG00000177731	0.30577130334128055	[85]	[109,43,1]	3	hSpCas9	negative selection	1454929
18254819	18254842	17	-	26627737	HeLa	viability after 8 days	ACCAGCTGACAGAGTGCCCGCGG	FLII	ENSG00000177731	1.2873702071747721	[302]	[281,416,261]	8	hSpCas9	negative selection	1454930
18255240	18255263	17	+	26627737	HeLa	viability after 8 days	ACTGTTGGCTCGGGCCACGATGG	FLII	ENSG00000177731	0.20669336527125015	[192]	[206,40,68]	2	hSpCas9	negative selection	1454931
18256515	18256538	17	+	26627737	HeLa	viability after 8 days	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	0.48062069653293993	[591]	[426,303,361]	4	hSpCas9	negative selection	1454932
18256959	18256982	17	+	26627737	HeLa	viability after 8 days	GGTTCAGCTTCAGCCACCGCAGG	FLII	ENSG00000177731	0.09565021889283257	[328]	[91,207,145]	0	hSpCas9	negative selection	1454933
18258647	18258670	17	+	26627737	HeLa	viability after 8 days	AGGTCCACGCCACGCACGAACGG	FLII	ENSG00000177731	0.8208491452464951	[379]	[307,312,260]	6	hSpCas9	negative selection	1454934
18254606	18254629	17	-	26627737	HeLa	viability after 12 days	GGACCTCAGCGAGAACCGCCTGG	FLII	ENSG00000177731	-0.028788276935258317	[85]	[39,59,1]	0	hSpCas9	negative selection	1537244
18254819	18254842	17	-	26627737	HeLa	viability after 12 days	ACCAGCTGACAGAGTGCCCGCGG	FLII	ENSG00000177731	0.8109926913935618	[302]	[389,115,168]	6	hSpCas9	negative selection	1537245
18255240	18255263	17	+	26627737	HeLa	viability after 12 days	ACTGTTGGCTCGGGCCACGATGG	FLII	ENSG00000177731	-0.16065530622566637	[192]	[47,74,89]	-1	hSpCas9	negative selection	1537246
18256515	18256538	17	+	26627737	HeLa	viability after 12 days	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	0.11872177975499776	[591]	[394,120,299]	1	hSpCas9	negative selection	1537247
18256959	18256982	17	+	26627737	HeLa	viability after 12 days	GGTTCAGCTTCAGCCACCGCAGG	FLII	ENSG00000177731	-0.1529536941479107	[328]	[76,117,170]	-1	hSpCas9	negative selection	1537248
18258647	18258670	17	+	26627737	HeLa	viability after 12 days	AGGTCCACGCCACGCACGAACGG	FLII	ENSG00000177731	0.7182603927813243	[379]	[337,214,228]	6	hSpCas9	negative selection	1537249
18254606	18254629	17	-	26627737	HeLa	viability after 15 days	GGACCTCAGCGAGAACCGCCTGG	FLII	ENSG00000177731	0.32890944503776254	[85]	[110,0,16]	2	hSpCas9	negative selection	1619559
18254819	18254842	17	-	26627737	HeLa	viability after 15 days	ACCAGCTGACAGAGTGCCCGCGG	FLII	ENSG00000177731	0.546953491686509	[302]	[37,305,199]	4	hSpCas9	negative selection	1619560
18255240	18255263	17	+	26627737	HeLa	viability after 15 days	ACTGTTGGCTCGGGCCACGATGG	FLII	ENSG00000177731	-0.26644249460971947	[192]	[35,74,86]	-2	hSpCas9	negative selection	1619561
18256515	18256538	17	+	26627737	HeLa	viability after 15 days	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	-0.079044327650726	[591]	[412,53,213]	0	hSpCas9	negative selection	1619562
18256959	18256982	17	+	26627737	HeLa	viability after 15 days	GGTTCAGCTTCAGCCACCGCAGG	FLII	ENSG00000177731	0.43678151570602	[328]	[201,203,133]	3	hSpCas9	negative selection	1619563
18258647	18258670	17	+	26627737	HeLa	viability after 15 days	AGGTCCACGCCACGCACGAACGG	FLII	ENSG00000177731	0.38162371759955893	[379]	[165,141,304]	3	hSpCas9	negative selection	1619564
18254606	18254629	17	-	26627737	HeLa	viability after 18 days	GGACCTCAGCGAGAACCGCCTGG	FLII	ENSG00000177731	0.4526428956589481	[85]	[81,0,16]	4	hSpCas9	negative selection	1701874
18254819	18254842	17	-	26627737	HeLa	viability after 18 days	ACCAGCTGACAGAGTGCCCGCGG	FLII	ENSG00000177731	0.588342963783993	[302]	[23,267,199]	5	hSpCas9	negative selection	1701875
18255240	18255263	17	+	26627737	HeLa	viability after 18 days	ACTGTTGGCTCGGGCCACGATGG	FLII	ENSG00000177731	-0.18946494184525653	[192]	[27,65,86]	-2	hSpCas9	negative selection	1701876
18256515	18256538	17	+	26627737	HeLa	viability after 18 days	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	-0.05736395684477813	[591]	[277,51,213]	0	hSpCas9	negative selection	1701877
18256959	18256982	17	+	26627737	HeLa	viability after 18 days	GGTTCAGCTTCAGCCACCGCAGG	FLII	ENSG00000177731	0.4291139944500345	[328]	[131,170,133]	3	hSpCas9	negative selection	1701878
18258647	18258670	17	+	26627737	HeLa	viability after 18 days	AGGTCCACGCCACGCACGAACGG	FLII	ENSG00000177731	0.41780346172271016	[379]	[124,112,304]	3	hSpCas9	negative selection	1701879
18254606	18254629	17	-	26627737	HCT116	viability after 6 days	GGACCTCAGCGAGAACCGCCTGG	FLII	ENSG00000177731	-0.038299664318076854	[115]	[0,26]	0	hSpCas9	negative selection	1784189
18254819	18254842	17	-	26627737	HCT116	viability after 6 days	ACCAGCTGACAGAGTGCCCGCGG	FLII	ENSG00000177731	0.3928163157379677	[851]	[365,70]	2	hSpCas9	negative selection	1784190
18255240	18255263	17	+	26627737	HCT116	viability after 6 days	ACTGTTGGCTCGGGCCACGATGG	FLII	ENSG00000177731	-0.6105301251448481	[811]	[42,105]	-3	hSpCas9	negative selection	1784191
18256515	18256538	17	+	26627737	HCT116	viability after 6 days	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	-1.615831482881266	[1111]	[96,34]	-7	hSpCas9	negative selection	1784192
18256959	18256982	17	+	26627737	HCT116	viability after 6 days	GGTTCAGCTTCAGCCACCGCAGG	FLII	ENSG00000177731	-1.5474948910067465	[482]	[34,20]	-7	hSpCas9	negative selection	1784193
18258647	18258670	17	+	26627737	HCT116	viability after 6 days	AGGTCCACGCCACGCACGAACGG	FLII	ENSG00000177731	-0.29370913643101093	[427]	[41,61]	-2	hSpCas9	negative selection	1784194
18254606	18254629	17	-	26627737	HCT116	viability after 8 days	GGACCTCAGCGAGAACCGCCTGG	FLII	ENSG00000177731	-1.118298447021352	[139]	[59,7,38]	-8	hSpCas9	negative selection	1866504
18254819	18254842	17	-	26627737	HCT116	viability after 8 days	ACCAGCTGACAGAGTGCCCGCGG	FLII	ENSG00000177731	0.5305379725584798	[241]	[150,141,282]	5	hSpCas9	negative selection	1866505
18255240	18255263	17	+	26627737	HCT116	viability after 8 days	ACTGTTGGCTCGGGCCACGATGG	FLII	ENSG00000177731	-0.6736569575906612	[317]	[163,95,70]	-7	hSpCas9	negative selection	1866506
18256515	18256538	17	+	26627737	HCT116	viability after 8 days	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	0.1305705671603804	[517]	[313,274,347]	1	hSpCas9	negative selection	1866507
18256959	18256982	17	+	26627737	HCT116	viability after 8 days	GGTTCAGCTTCAGCCACCGCAGG	FLII	ENSG00000177731	-0.7338385487216548	[267]	[55,136,72]	-7	hSpCas9	negative selection	1866508
18258647	18258670	17	+	26627737	HCT116	viability after 8 days	AGGTCCACGCCACGCACGAACGG	FLII	ENSG00000177731	0.11630910753417995	[397]	[236,225,249]	1	hSpCas9	negative selection	1866509
18254606	18254629	17	-	26627737	HCT116	viability after 9 days	GGACCTCAGCGAGAACCGCCTGG	FLII	ENSG00000177731	0.35358373396855214	[115]	[14,58]	2	hSpCas9	negative selection	1948819
18254819	18254842	17	-	26627737	HCT116	viability after 9 days	ACCAGCTGACAGAGTGCCCGCGG	FLII	ENSG00000177731	-0.7613046283244784	[851]	[217,67]	-5	hSpCas9	negative selection	1948820
18255240	18255263	17	+	26627737	HCT116	viability after 9 days	ACTGTTGGCTCGGGCCACGATGG	FLII	ENSG00000177731	-0.710939040050901	[811]	[170,101]	-5	hSpCas9	negative selection	1948821
18256515	18256538	17	+	26627737	HCT116	viability after 9 days	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	-1.0198599487969742	[1111]	[189,111]	-6	hSpCas9	negative selection	1948822
18256959	18256982	17	+	26627737	HCT116	viability after 9 days	GGTTCAGCTTCAGCCACCGCAGG	FLII	ENSG00000177731	-0.2758748796862596	[482]	[29,166]	-2	hSpCas9	negative selection	1948823
18258647	18258670	17	+	26627737	HCT116	viability after 9 days	AGGTCCACGCCACGCACGAACGG	FLII	ENSG00000177731	1.0936741017781653	[427]	[344,163]	7	hSpCas9	negative selection	1948824
18254606	18254629	17	-	26627737	HCT116	viability after 12 days	GGACCTCAGCGAGAACCGCCTGG	FLII	ENSG00000177731	-0.5271778782354539	[139]	[38,41,72]	-5	hSpCas9	negative selection	2031134
18254819	18254842	17	-	26627737	HCT116	viability after 12 days	ACCAGCTGACAGAGTGCCCGCGG	FLII	ENSG00000177731	0.4772931459230938	[241]	[113,148,272]	4	hSpCas9	negative selection	2031135
18255240	18255263	17	+	26627737	HCT116	viability after 12 days	ACTGTTGGCTCGGGCCACGATGG	FLII	ENSG00000177731	-0.3986737020930819	[317]	[184,118,70]	-4	hSpCas9	negative selection	2031136
18256515	18256538	17	+	26627737	HCT116	viability after 12 days	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	-0.3271307060951161	[517]	[208,229,212]	-3	hSpCas9	negative selection	2031137
18256959	18256982	17	+	26627737	HCT116	viability after 12 days	GGTTCAGCTTCAGCCACCGCAGG	FLII	ENSG00000177731	-0.18109123997373883	[267]	[100,176,97]	-2	hSpCas9	negative selection	2031138
18258647	18258670	17	+	26627737	HCT116	viability after 12 days	AGGTCCACGCCACGCACGAACGG	FLII	ENSG00000177731	0.6197755816540729	[397]	[215,425,333]	6	hSpCas9	negative selection	2031139
18254606	18254629	17	-	26627737	HCT116	viability after 15 days	GGACCTCAGCGAGAACCGCCTGG	FLII	ENSG00000177731	-0.023095335225154168	[139]	[101,45,91]	0	hSpCas9	negative selection	2113449
18254819	18254842	17	-	26627737	HCT116	viability after 15 days	ACCAGCTGACAGAGTGCCCGCGG	FLII	ENSG00000177731	0.4535185392285896	[241]	[314,153,117]	4	hSpCas9	negative selection	2113450
18255240	18255263	17	+	26627737	HCT116	viability after 15 days	ACTGTTGGCTCGGGCCACGATGG	FLII	ENSG00000177731	-0.37144465098376606	[317]	[214,117,99]	-4	hSpCas9	negative selection	2113451
18256515	18256538	17	+	26627737	HCT116	viability after 15 days	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	0.3281659155872454	[517]	[453,368,307]	3	hSpCas9	negative selection	2113452
18256959	18256982	17	+	26627737	HCT116	viability after 15 days	GGTTCAGCTTCAGCCACCGCAGG	FLII	ENSG00000177731	-0.09863677159384127	[267]	[111,141,172]	-1	hSpCas9	negative selection	2113453
18258647	18258670	17	+	26627737	HCT116	viability after 15 days	AGGTCCACGCCACGCACGAACGG	FLII	ENSG00000177731	0.6459418681386373	[397]	[334,359,374]	6	hSpCas9	negative selection	2113454
18254606	18254629	17	-	26627737	HCT116	viability after 18 days	GGACCTCAGCGAGAACCGCCTGG	FLII	ENSG00000177731	-0.39575127667301735	[139]	[61,49,41]	-4	hSpCas9	negative selection	2195764
18254819	18254842	17	-	26627737	HCT116	viability after 18 days	ACCAGCTGACAGAGTGCCCGCGG	FLII	ENSG00000177731	1.1986444285781528	[241]	[341,174,295]	8	hSpCas9	negative selection	2195765
18255240	18255263	17	+	26627737	HCT116	viability after 18 days	ACTGTTGGCTCGGGCCACGATGG	FLII	ENSG00000177731	-0.6629868415958691	[317]	[187,27,78]	-6	hSpCas9	negative selection	2195766
18256515	18256538	17	+	26627737	HCT116	viability after 18 days	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	-0.13431379578440572	[517]	[236,185,265]	-1	hSpCas9	negative selection	2195767
18256959	18256982	17	+	26627737	HCT116	viability after 18 days	GGTTCAGCTTCAGCCACCGCAGG	FLII	ENSG00000177731	0.205385502419758	[267]	[189,116,142]	1	hSpCas9	negative selection	2195768
18258647	18258670	17	+	26627737	HCT116	viability after 18 days	AGGTCCACGCCACGCACGAACGG	FLII	ENSG00000177731	0.6473678994825176	[397]	[180,351,370]	5	hSpCas9	negative selection	2195769
18256926	18256949	17	-	24336569	HL60	viability	CTGCTACCTGCCCGAGGAGCTGG	FLII	ENSG00000177731	0.6383007527837016	[404]	[1333]	5	hSpCas9	negative selection	2266628
18256932	18256955	17	-	24336569	HL60	viability	TGGCCTCTGCTACCTGCCCGAGG	FLII	ENSG00000177731	-0.19100694753519193	[464]	[861]	-2	hSpCas9	negative selection	2266629
18256938	18256961	17	+	24336569	HL60	viability	GCAGGTAGCAGAGGCCAGTGCGG	FLII	ENSG00000177731	-1.5169963040231185	[1795]	[1327]	-8	hSpCas9	negative selection	2266630
18256952	18256975	17	-	24336569	HL60	viability	TGGCTGAAGCTGAACCGCACTGG	FLII	ENSG00000177731	0.37693443880859	[380]	[1046]	3	hSpCas9	negative selection	2266631
18256959	18256982	17	+	24336569	HL60	viability	GGTTCAGCTTCAGCCACCGCAGG	FLII	ENSG00000177731	-1.9011224832412454	[735]	[416]	-9	hSpCas9	negative selection	2266632
18256969	18256992	17	+	24336569	HL60	viability	CAGCCACCGCAGGCTGGTCATGG	FLII	ENSG00000177731	0.21024510484260223	[356]	[873]	2	hSpCas9	negative selection	2266633
18256975	18256998	17	-	24336569	HL60	viability	TCAAGGCCATGACCAGCCTGCGG	FLII	ENSG00000177731	0.17870923328875404	[672]	[1611]	1	hSpCas9	negative selection	2266634
18256985	18257008	17	+	24336569	HL60	viability	GTCATGGCCTTGACATTCTCAGG	FLII	ENSG00000177731	0.957904452420398	[243]	[1002]	7	hSpCas9	negative selection	2266635
18256992	18257015	17	-	24336569	HL60	viability	CTACTTCCCTGAGAATGTCAAGG	FLII	ENSG00000177731	-0.6155542715515034	[1211]	[1673]	-5	hSpCas9	negative selection	2266636
18257001	18257024	17	+	24336569	HL60	viability	TCTCAGGGAAGTAGCCGCCCTGG	FLII	ENSG00000177731	-0.7896256661477244	[280]	[343]	-6	hSpCas9	negative selection	2266637
18256926	18256949	17	-	24336569	KBM7	viability	CTGCTACCTGCCCGAGGAGCTGG	FLII	ENSG00000177731	0.5037860282002408	[361]	[1399]	4	hSpCas9	negative selection	2333805
18256932	18256955	17	-	24336569	KBM7	viability	TGGCCTCTGCTACCTGCCCGAGG	FLII	ENSG00000177731	-1.5985550951902048	[623]	[561]	-8	hSpCas9	negative selection	2333806
18256938	18256961	17	+	24336569	KBM7	viability	GCAGGTAGCAGAGGCCAGTGCGG	FLII	ENSG00000177731	-4.180356993751655	[1375]	[206]	-9	hSpCas9	negative selection	2333807
18256952	18256975	17	-	24336569	KBM7	viability	TGGCTGAAGCTGAACCGCACTGG	FLII	ENSG00000177731	-1.3832900681939024	[394]	[412]	-7	hSpCas9	negative selection	2333808
18256959	18256982	17	+	24336569	KBM7	viability	GGTTCAGCTTCAGCCACCGCAGG	FLII	ENSG00000177731	-1.0598676826161775	[492]	[644]	-6	hSpCas9	negative selection	2333809
18256969	18256992	17	+	24336569	KBM7	viability	CAGCCACCGCAGGCTGGTCATGG	FLII	ENSG00000177731	0.26837939676782363	[504]	[1658]	2	hSpCas9	negative selection	2333810
18256975	18256998	17	-	24336569	KBM7	viability	TCAAGGCCATGACCAGCCTGCGG	FLII	ENSG00000177731	-0.6390265201336564	[687]	[1204]	-5	hSpCas9	negative selection	2333811
18256985	18257008	17	+	24336569	KBM7	viability	GTCATGGCCTTGACATTCTCAGG	FLII	ENSG00000177731	0.0015289788196536543	[407]	[1113]	0	hSpCas9	negative selection	2333812
18256992	18257015	17	-	24336569	KBM7	viability	CTACTTCCCTGAGAATGTCAAGG	FLII	ENSG00000177731	-0.07736516704606877	[616]	[1594]	0	hSpCas9	negative selection	2333813
18257001	18257024	17	+	24336569	KBM7	viability	TCTCAGGGAAGTAGCCGCCCTGG	FLII	ENSG00000177731	-1.9621523693786407	[249]	[174]	-8	hSpCas9	negative selection	2333814
18249976	18249999	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCATGTGCTACCACGCCTAG	FLII	ENSG00000177731	3.748247150670283	[1,20]	[67,2]	9	dCas9-VP64	positive selection	2410084
18258618	18258641	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAACGACTTCAAGGTGAGCCGGG	FLII	ENSG00000177731	-0.045324079373439075	[18,353]	[9,72]	0	dCas9-VP64	positive selection	2415891
18258670	18258693	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGCACCCCGGTGGCCTCCATGG	FLII	ENSG00000177731	-1.3067481467884372	[334,10]	[25,2]	-7	dCas9-VP64	positive selection	2415892
18258641	18258664	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	GTGCGTGGCGTGGACCTCAGCGG	FLII	ENSG00000177731	1.285057749795599	[20,6]	[10,2]	5	dCas9-VP64	positive selection	2415893
18250029	18250052	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAGAATCGCTTGAACCCTGGGGG	FLII	ENSG00000177731	-0.5583774166941213	[49,17]	[4,3]	-3	dCas9-VP64	positive selection	2470293
18249976	18249999	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCATGTGCTACCACGCCTAG	FLII	ENSG00000177731	-0.05566307319411967	[8,287]	[6,81]	0	dCas9-VP64	positive selection	2505339
18258618	18258641	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAACGACTTCAAGGTGAGCCGGG	FLII	ENSG00000177731	-0.36393408680946954	[94,128]	[38,17]	-4	dCas9-VP64	positive selection	2511146
18258670	18258693	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGCACCCCGGTGGCCTCCATGG	FLII	ENSG00000177731	-0.0011919619696760253	[98,84]	[31,27]	0	dCas9-VP64	positive selection	2511147
18258641	18258664	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	GTGCGTGGCGTGGACCTCAGCGG	FLII	ENSG00000177731	-0.10143647043977544	[49,69]	[14,19]	-1	dCas9-VP64	positive selection	2511148
18250029	18250052	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAGAATCGCTTGAACCCTGGGGG	FLII	ENSG00000177731	-1.4985881155418108	[182,12]	[19,2]	-9	dCas9-VP64	positive selection	2565548
18252480	18252503	17	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGAAGCCATCCATTTCCTGACGG	FLII	ENSG00000177731	-0.571195475859699	[3,4]	[2,1]	-7	hSpCas9	positive selection	2988829
18251381	18251404	17	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTACTCCGAGTTCTTCACGGAGG	FLII	ENSG00000177731	-0.2951024549910674	[3,3]	[0,3]	-4	hSpCas9	positive selection	2988830
18256545	18256568	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGACAGCTCCCCATGAAGCGTGG	FLII	ENSG00000177731	-0.39540913856643956	[2,2]	[1,0]	-5	hSpCas9	positive selection	2988831
18253365	18253388	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTGAGCTTGCCAATGCCTGAGGG	FLII	ENSG00000177731	-0.6987469380090598	[3,3]	[2,0]	-8	hSpCas9	positive selection	2988832
18252480	18252503	17	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGAAGCCATCCATTTCCTGACGG	FLII	ENSG00000177731	-1.0049970567939182	[3,3]	[1,0]	-9	hSpCas9	positive selection	3056687
18251381	18251404	17	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTACTCCGAGTTCTTCACGGAGG	FLII	ENSG00000177731	-0.3875283795340577	[3,3]	[1,1]	-6	hSpCas9	positive selection	3056688
18256545	18256568	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGACAGCTCCCCATGAAGCGTGG	FLII	ENSG00000177731	-0.5386674473747457	[2,2]	[1,0]	-7	hSpCas9	positive selection	3056689
18253365	18253388	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTGAGCTTGCCAATGCCTGAGGG	FLII	ENSG00000177731	-0.5974810044265805	[3,3]	[2,0]	-7	hSpCas9	positive selection	3056690
18256554	18256577		-	24336571	A375	resistance to PLX after 7 days	AACAACCTGACCACGCTTCATGG	FLII	ENSG00000177731	-0.22586030553535852	[47,47]	[40,39]	-7	hSpCas9	positive selection	3114924
18256515	18256538		+	24336571	A375	resistance to PLX after 7 days	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	0.22085968005620416	[20,22]	[26,23]	6	hSpCas9	positive selection	3114925
18254082	18254105		+	24336571	A375	resistance to PLX after 7 days	CGAGGTTGCTCAGACCCTCCAGG	FLII	ENSG00000177731	0.0025836527911815566	[67,76]	[67,76]	0	hSpCas9	positive selection	3114926
18256554	18256577		-	24336571	A375	resistance to PLX after 14 days	AACAACCTGACCACGCTTCATGG	FLII	ENSG00000177731	-0.28179324731086286	[36,42]	[14,14]	-3	hSpCas9	positive selection	3172717
18256515	18256538		+	24336571	A375	resistance to PLX after 14 days	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	0.357649729782209	[18,24]	[10,14]	3	hSpCas9	positive selection	3172718
18254082	18254105		+	24336571	A375	resistance to PLX after 14 days	CGAGGTTGCTCAGACCCTCCAGG	FLII	ENSG00000177731	-0.01117715857422752	[87,85]	[34,44]	0	hSpCas9	positive selection	3172719
18256554	18256577		-	24336571	A375	viability after 7 days	AACAACCTGACCACGCTTCATGG	FLII	ENSG00000177731	0.36357072206480634	[38]	[47,47]	5	hSpCas9	negative selection	3230510
18256515	18256538		+	24336571	A375	viability after 7 days	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	-0.15514443780079745	[25]	[20,22]	-2	hSpCas9	negative selection	3230511
18254082	18254105		+	24336571	A375	viability after 7 days	CGAGGTTGCTCAGACCCTCCAGG	FLII	ENSG00000177731	0.5532102949042319	[51]	[67,76]	8	hSpCas9	negative selection	3230512
18256554	18256577		-	24336571	A375	viability after 14 days	AACAACCTGACCACGCTTCATGG	FLII	ENSG00000177731	0.1265438313920202	[38]	[36,42]	1	hSpCas9	negative selection	3288303
18256515	18256538		+	24336571	A375	viability after 14 days	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	-0.14096922436768566	[25]	[18,24]	-2	hSpCas9	negative selection	3288304
18254082	18254105		+	24336571	A375	viability after 14 days	CGAGGTTGCTCAGACCCTCCAGG	FLII	ENSG00000177731	0.8259408138318245	[51]	[87,85]	9	hSpCas9	negative selection	3288305
18256515	18256538	17	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	1.7331494268941605	[48,42]	[0,0]	7	hSpCas9	positive selection	3350202
18256554	18256577	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	AACAACCTGACCACGCTTCATGG	FLII	ENSG00000177731	3.036998839724291	[443,431]	[5,40]	8	hSpCas9	positive selection	3350203
18253390	18253413	17	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCCGTCAAAGTCCAGCTTGTTGG	FLII	ENSG00000177731	1.1116487562502002	[176,176]	[0,3]	5	hSpCas9	positive selection	3350204
18253318	18253341	17	+	27383988	293T	resistance to West Nile virus (flavivirus)	GACCAGCTCCAGGTTGTTGTTGG	FLII	ENSG00000177731	-0.028076007416413237	[155,155]	[0,0]	0	hSpCas9	positive selection	3369417
18254163	18254186	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	CAGGCAGCTCCCAGCGATGACGG	FLII	ENSG00000177731	0.038157690983673484	[148,148]	[0,0]	0	hSpCas9	positive selection	3369418
18254082	18254105	17	+	27383988	293T	resistance to West Nile virus (flavivirus)	CGAGGTTGCTCAGACCCTCCAGG	FLII	ENSG00000177731	-1.0280760074164133	[311,311]	[0,0]	-7	hSpCas9	positive selection	3369419
18252480	18252503	17	-	26780180	HT29	viability (Avana library 4 designs)	AGAAGCCATCCATTTCCTGACGG	FLII	ENSG00000177731	2.91982680403725	[]	[]	8	hSpCas9	negative selection	3425739
18251381	18251404	17	-	26780180	HT29	viability (Avana library 4 designs)	CTACTCCGAGTTCTTCACGGAGG	FLII	ENSG00000177731	3.00114680989062	[]	[]	8	hSpCas9	negative selection	3425740
18256544	18256567	17	+	26780180	HT29	viability (Avana library 4 designs)	GGACAGCTCCCCATGAAGCGTGG	FLII	ENSG00000177731	4.1676991859918	[]	[]	9	hSpCas9	negative selection	3425741
18253364	18253387	17	+	26780180	HT29	viability (Avana library 4 designs)	GTGAGCTTGCCAATGCCTGAGGG	FLII	ENSG00000177731	4.44429605027119	[]	[]	9	hSpCas9	negative selection	3425742
18253364	18253387	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTGAGCTTGCCAATGCCTGAGGG	FLII	ENSG00000177731	-0.621598101203901	[]	[]	-1	hSpCas9	negative selection	3508015
18256544	18256567	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGACAGCTCCCCATGAAGCGTGG	FLII	ENSG00000177731	-3.12929172166185	[]	[]	-4	hSpCas9	negative selection	3508016
18251381	18251404	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTACTCCGAGTTCTTCACGGAGG	FLII	ENSG00000177731	-4.54506918521433	[]	[]	-5	hSpCas9	negative selection	3508017
18252480	18252503	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGAAGCCATCCATTTCCTGACGG	FLII	ENSG00000177731	-6.22852012478589	[]	[]	-6	hSpCas9	negative selection	3508018
18250960	18250983	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	GATCTACTACTGGATTGGCGGGG	FLII	ENSG00000177731	-18.0331075537714	[]	[]	-9	hSpCas9	negative selection	3508019
18248836	18248859	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTAGACATCTACGTATGGCGGGG	FLII	ENSG00000177731	-8.80124767647126	[]	[]	-7	hSpCas9	negative selection	3508020
18253364	18253387	17	+	26780180	A375	viability (Avana lentiGuide)	GTGAGCTTGCCAATGCCTGAGGG	FLII	ENSG00000177731	10.5581424333065	[]	[]	7	hSpCas9	negative selection	3616674
18256544	18256567	17	+	26780180	A375	viability (Avana lentiGuide)	GGACAGCTCCCCATGAAGCGTGG	FLII	ENSG00000177731	8.13167444327697	[]	[]	6	hSpCas9	negative selection	3616675
18251381	18251404	17	-	26780180	A375	viability (Avana lentiGuide)	CTACTCCGAGTTCTTCACGGAGG	FLII	ENSG00000177731	26.0200779700122	[]	[]	9	hSpCas9	negative selection	3616676
18252480	18252503	17	-	26780180	A375	viability (Avana lentiGuide)	AGAAGCCATCCATTTCCTGACGG	FLII	ENSG00000177731	7.57225149561431	[]	[]	6	hSpCas9	negative selection	3616677
18250960	18250983	17	-	26780180	A375	viability (Avana lentiGuide)	GATCTACTACTGGATTGGCGGGG	FLII	ENSG00000177731	26.6254511413141	[]	[]	9	hSpCas9	negative selection	3616678
18248836	18248859	17	-	26780180	A375	viability (Avana lentiGuide)	CTAGACATCTACGTATGGCGGGG	FLII	ENSG00000177731	28.1383338148973	[]	[]	9	hSpCas9	negative selection	3616679
18253364	18253387	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTGAGCTTGCCAATGCCTGAGGG	FLII	ENSG00000177731	0.20293752520425973	[5]	[6,5]	5	hSpCas9	positive selection	3725333
18256544	18256567	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGACAGCTCCCCATGAAGCGTGG	FLII	ENSG00000177731	0.19693288475409643	[4]	[5,3]	5	hSpCas9	positive selection	3725334
18251381	18251404	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTACTCCGAGTTCTTCACGGAGG	FLII	ENSG00000177731	-0.13728960553004732	[4]	[5,2]	-2	hSpCas9	positive selection	3725335
18252480	18252503	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGAAGCCATCCATTTCCTGACGG	FLII	ENSG00000177731	-0.35991094843420274	[5]	[3,3]	-5	hSpCas9	positive selection	3725336
18250960	18250983	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATCTACTACTGGATTGGCGGGG	FLII	ENSG00000177731	-0.01068347503863222	[5]	[5,4]	0	hSpCas9	positive selection	3725337
18248836	18248859	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTAGACATCTACGTATGGCGGGG	FLII	ENSG00000177731	-0.12588515704922276	[4]	[3,3]	-2	hSpCas9	positive selection	3725338
18253364	18253387	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTGAGCTTGCCAATGCCTGAGGG	FLII	ENSG00000177731	-0.4396731436176512	[6]	[2,4]	-5	hSpCas9	positive selection	3833940
18256544	18256567	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGACAGCTCCCCATGAAGCGTGG	FLII	ENSG00000177731	-0.6498699873746463	[5]	[3,0]	-7	hSpCas9	positive selection	3833941
18251381	18251404	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTACTCCGAGTTCTTCACGGAGG	FLII	ENSG00000177731	-0.658860197407144	[5]	[3,1]	-7	hSpCas9	positive selection	3833942
18252480	18252503	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGAAGCCATCCATTTCCTGACGG	FLII	ENSG00000177731	0.049432258952751704	[5]	[3,6]	1	hSpCas9	positive selection	3833943
18250960	18250983	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATCTACTACTGGATTGGCGGGG	FLII	ENSG00000177731	0.10388515004107438	[5]	[3,5]	2	hSpCas9	positive selection	3833944
18248836	18248859	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTAGACATCTACGTATGGCGGGG	FLII	ENSG00000177731	-0.9993103679846607	[5]	[0,2]	-8	hSpCas9	positive selection	3833945
18256554	18256577	17	-	26780180	A375	viability	AACAACCTGACCACGCTTCATGG	FLII	ENSG00000177731	0.334584237463672	[]	[]	0	hSpCas9	negative selection	3941229
18254163	18254186	17	-	26780180	A375	viability	CAGGCAGCTCCCAGCGATGACGG	FLII	ENSG00000177731	1.55155675708147	[]	[]	8	hSpCas9	negative selection	3941230
18256515	18256538	17	+	26780180	A375	viability	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	1.3328453971618	[]	[]	7	hSpCas9	negative selection	3941231
18253390	18253413	17	+	26780180	A375	viability	CCCGTCAAAGTCCAGCTTGTTGG	FLII	ENSG00000177731	0.862725220053659	[]	[]	3	hSpCas9	negative selection	3941232
18254082	18254105	17	+	26780180	A375	viability	CGAGGTTGCTCAGACCCTCCAGG	FLII	ENSG00000177731	1.80092660773793	[]	[]	9	hSpCas9	negative selection	3941233
18253318	18253341	17	+	26780180	A375	viability	GACCAGCTCCAGGTTGTTGTTGG	FLII	ENSG00000177731	1.55214258521304	[]	[]	8	hSpCas9	negative selection	3941234
18256554	18256577	17	-	26780180	HT29	viability (GeCKOv2 library)	AACAACCTGACCACGCTTCATGG	FLII	ENSG00000177731	-0.283483692292008	[]	[]	-7	hSpCas9	negative selection	4049195
18254163	18254186	17	-	26780180	HT29	viability (GeCKOv2 library)	CAGGCAGCTCCCAGCGATGACGG	FLII	ENSG00000177731	2.14444349461294	[]	[]	9	hSpCas9	negative selection	4049196
18256515	18256538	17	+	26780180	HT29	viability (GeCKOv2 library)	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	1.53360822249614	[]	[]	7	hSpCas9	negative selection	4049197
18253390	18253413	17	+	26780180	HT29	viability (GeCKOv2 library)	CCCGTCAAAGTCCAGCTTGTTGG	FLII	ENSG00000177731	0.157840157809841	[]	[]	0	hSpCas9	negative selection	4049198
18254082	18254105	17	+	26780180	HT29	viability (GeCKOv2 library)	CGAGGTTGCTCAGACCCTCCAGG	FLII	ENSG00000177731	1.82498766503299	[]	[]	8	hSpCas9	negative selection	4049199
18253318	18253341	17	+	26780180	HT29	viability (GeCKOv2 library)	GACCAGCTCCAGGTTGTTGTTGG	FLII	ENSG00000177731	1.97314160256084	[]	[]	9	hSpCas9	negative selection	4049200
18256554	18256577	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AACAACCTGACCACGCTTCATGG	FLII	ENSG00000177731	0.17892793255899453	[5]	[4,3]	4	hSpCas9	positive selection	4137988
18256515	18256538	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	0.10808034876207731	[4]	[2,3]	2	hSpCas9	positive selection	4137989
18254082	18254105	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGAGGTTGCTCAGACCCTCCAGG	FLII	ENSG00000177731	0.10354234261071715	[6]	[4,5]	2	hSpCas9	positive selection	4137990
18256554	18256577	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AACAACCTGACCACGCTTCATGG	FLII	ENSG00000177731	0.9008172268329144	[6]	[5,4,4,5]	6	hSpCas9	positive selection	4202010
18256515	18256538	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	1.1252316925449843	[4]	[4,4,3,5]	8	hSpCas9	positive selection	4202011
18254082	18254105	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGAGGTTGCTCAGACCCTCCAGG	FLII	ENSG00000177731	1.247097269192825	[4]	[5,4,5,4]	9	hSpCas9	positive selection	4202012
18256515	18256538	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	-0.4332579874345955	[2]	[1,0]	-7	hSpCas9	positive selection	4271306
18256554	18256577	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AACAACCTGACCACGCTTCATGG	FLII	ENSG00000177731	0.5296090468485117	[4]	[4,4]	9	hSpCas9	positive selection	4271307
18253390	18253413	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCCGTCAAAGTCCAGCTTGTTGG	FLII	ENSG00000177731	0.24584017042844808	[3]	[3,2]	5	hSpCas9	positive selection	4271308
18253318	18253341	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GACCAGCTCCAGGTTGTTGTTGG	FLII	ENSG00000177731	-0.20793461017203022	[2]	[2,0]	-4	hSpCas9	positive selection	4335571
18254163	18254186	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGGCAGCTCCCAGCGATGACGG	FLII	ENSG00000177731	-0.28351052991700465	[2]	[1,1]	-5	hSpCas9	positive selection	4335572
18254082	18254105	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGAGGTTGCTCAGACCCTCCAGG	FLII	ENSG00000177731	-0.4359463215792711	[3]	[3,0]	-7	hSpCas9	positive selection	4335573
18250908	18250930	17	+	27760321	OCIAML3	viability	CGCAAGTTGACAGCGTGGATGG	FLII	ENSG00000177731	-2.6108811619343903	[579,487]	[25,122]	-9	hSpCas9	negative selection	4401478
18251288	18251310	17	-	27760321	OCIAML3	viability	TTCCACGGCAAGTTCTACGAGG	FLII	ENSG00000177731	0.013463215741293277	[286,268]	[183,265]	0	hSpCas9	negative selection	4401479
18251393	18251415	17	+	27760321	OCIAML3	viability	ACTCGGAGTAGTCAAGGCGGGG	FLII	ENSG00000177731	-0.14229584297737796	[669,591]	[306,627]	-1	hSpCas9	negative selection	4401480
18251767	18251789	17	-	27760321	OCIAML3	viability	TCGCAAGATGCGACTGCGGAGG	FLII	ENSG00000177731	0.34812248837187276	[572,594]	[512,676]	4	hSpCas9	negative selection	4401481
18252067	18252089	17	+	27760321	OCIAML3	viability	TCGATGTTGTACCACTCAGCGG	FLII	ENSG00000177731	-1.0390972855708578	[351,308]	[72,193]	-7	hSpCas9	negative selection	4401482
18250908	18250930	17	+	27760321	OCIAML2	viability	CGCAAGTTGACAGCGTGGATGG	FLII	ENSG00000177731	-1.7710424668527078	[579,487]	[91,170]	-9	hSpCas9	negative selection	4484941
18251288	18251310	17	-	27760321	OCIAML2	viability	TTCCACGGCAAGTTCTACGAGG	FLII	ENSG00000177731	-0.5418878410632056	[286,268]	[154,153]	-6	hSpCas9	negative selection	4484942
18251393	18251415	17	+	27760321	OCIAML2	viability	ACTCGGAGTAGTCAAGGCGGGG	FLII	ENSG00000177731	-0.0062005375220287595	[669,591]	[496,520]	0	hSpCas9	negative selection	4484943
18251767	18251789	17	-	27760321	OCIAML2	viability	TCGCAAGATGCGACTGCGGAGG	FLII	ENSG00000177731	-0.34753675629520786	[572,594]	[338,417]	-4	hSpCas9	negative selection	4484944
18252067	18252089	17	+	27760321	OCIAML2	viability	TCGATGTTGTACCACTCAGCGG	FLII	ENSG00000177731	-0.6468097594051421	[351,308]	[172,166]	-6	hSpCas9	negative selection	4484945
18250908	18250930	17	+	27760321	MV411	viability	CGCAAGTTGACAGCGTGGATGG	FLII	ENSG00000177731	-2.515890998365571	[579,487]	[34,100]	-9	hSpCas9	negative selection	4568404
18251288	18251310	17	-	27760321	MV411	viability	TTCCACGGCAAGTTCTACGAGG	FLII	ENSG00000177731	0.5667688755982261	[286,268]	[151,451]	4	hSpCas9	negative selection	4568405
18251393	18251415	17	+	27760321	MV411	viability	ACTCGGAGTAGTCAAGGCGGGG	FLII	ENSG00000177731	-0.35657290833223443	[669,591]	[362,266]	-3	hSpCas9	negative selection	4568406
18251767	18251789	17	-	27760321	MV411	viability	TCGCAAGATGCGACTGCGGAGG	FLII	ENSG00000177731	0.1834026444353103	[572,594]	[364,551]	1	hSpCas9	negative selection	4568407
18252067	18252089	17	+	27760321	MV411	viability	TCGATGTTGTACCACTCAGCGG	FLII	ENSG00000177731	-0.9360991449680667	[351,308]	[56,198]	-6	hSpCas9	negative selection	4568408
18250908	18250930	17	+	27760321	HL60	viability	CGCAAGTTGACAGCGTGGATGG	FLII	ENSG00000177731	-2.726998416555732	[579,487]	[36,95]	-9	hSpCas9	negative selection	4651867
18251288	18251310	17	-	27760321	HL60	viability	TTCCACGGCAAGTTCTACGAGG	FLII	ENSG00000177731	-0.34250165146022393	[286,268]	[235,118]	-4	hSpCas9	negative selection	4651868
18251393	18251415	17	+	27760321	HL60	viability	ACTCGGAGTAGTCAAGGCGGGG	FLII	ENSG00000177731	-0.8482247673717591	[669,591]	[328,239]	-7	hSpCas9	negative selection	4651869
18251767	18251789	17	-	27760321	HL60	viability	TCGCAAGATGCGACTGCGGAGG	FLII	ENSG00000177731	-0.7006217982270613	[572,594]	[309,278]	-6	hSpCas9	negative selection	4651870
18252067	18252089	17	+	27760321	HL60	viability	TCGATGTTGTACCACTCAGCGG	FLII	ENSG00000177731	-1.0353378532617263	[351,308]	[162,97]	-7	hSpCas9	negative selection	4651871
18250908	18250930	17	+	27760321	HT1080	viability	CGCAAGTTGACAGCGTGGATGG	FLII	ENSG00000177731	-2.8208194234531394	[487,380]	[34,12]	-7	hSpCas9	negative selection	4735330
18251288	18251310	17	-	27760321	HT1080	viability	TTCCACGGCAAGTTCTACGAGG	FLII	ENSG00000177731	-3.3142063449691825	[268,209]	[0,18]	-7	hSpCas9	negative selection	4735331
18251393	18251415	17	+	27760321	HT1080	viability	ACTCGGAGTAGTCAAGGCGGGG	FLII	ENSG00000177731	-1.3173350830565465	[591,461]	[120,43]	-5	hSpCas9	negative selection	4735332
18251767	18251789	17	-	27760321	HT1080	viability	TCGCAAGATGCGACTGCGGAGG	FLII	ENSG00000177731	-0.8360812905681752	[594,463]	[152,79]	-4	hSpCas9	negative selection	4735333
18252067	18252089	17	+	27760321	HT1080	viability	TCGATGTTGTACCACTCAGCGG	FLII	ENSG00000177731	-2.9795912261184117	[308,240]	[0,27]	-7	hSpCas9	negative selection	4735334
18250908	18250930	17	+	27760321	HT29	viability after 7 days	CGCAAGTTGACAGCGTGGATGG	FLII	ENSG00000177731	0.0709242213388484	[487,380]	[656,602,511]	1	hSpCas9	negative selection	4818793
18251288	18251310	17	-	27760321	HT29	viability after 7 days	TTCCACGGCAAGTTCTACGAGG	FLII	ENSG00000177731	0.1565961702856174	[268,209]	[605,349,117]	2	hSpCas9	negative selection	4818794
18251393	18251415	17	+	27760321	HT29	viability after 7 days	ACTCGGAGTAGTCAAGGCGGGG	FLII	ENSG00000177731	0.0312421187277645	[591,461]	[807,824,466]	0	hSpCas9	negative selection	4818795
18251767	18251789	17	-	27760321	HT29	viability after 7 days	TCGCAAGATGCGACTGCGGAGG	FLII	ENSG00000177731	-0.4363937287125983	[594,463]	[639,480,409]	-6	hSpCas9	negative selection	4818796
18252067	18252089	17	+	27760321	HT29	viability after 7 days	TCGATGTTGTACCACTCAGCGG	FLII	ENSG00000177731	0.25088348927849485	[308,240]	[406,413,437]	4	hSpCas9	negative selection	4818797
18250908	18250930	17	+	27760321	HT29	viability after 25 days	CGCAAGTTGACAGCGTGGATGG	FLII	ENSG00000177731	-3.26033257555266	[487,380]	[14,96,44]	-8	hSpCas9	negative selection	4902256
18251288	18251310	17	-	27760321	HT29	viability after 25 days	TTCCACGGCAAGTTCTACGAGG	FLII	ENSG00000177731	-1.8067554237750385	[268,209]	[74,96,60]	-8	hSpCas9	negative selection	4902257
18251393	18251415	17	+	27760321	HT29	viability after 25 days	ACTCGGAGTAGTCAAGGCGGGG	FLII	ENSG00000177731	-1.031591586776218	[591,461]	[356,248,270]	-6	hSpCas9	negative selection	4902258
18251767	18251789	17	-	27760321	HT29	viability after 25 days	TCGCAAGATGCGACTGCGGAGG	FLII	ENSG00000177731	-1.1515857028927068	[594,463]	[376,109,328]	-7	hSpCas9	negative selection	4902259
18252067	18252089	17	+	27760321	HT29	viability after 25 days	TCGATGTTGTACCACTCAGCGG	FLII	ENSG00000177731	-1.6396671053301666	[308,240]	[86,48,174]	-7	hSpCas9	negative selection	4902260
18250908	18250930	17	+	27760321	HT29	viability after 22 days	CGCAAGTTGACAGCGTGGATGG	FLII	ENSG00000177731	-4.424973218047304	[487,380]	[0,20,48]	-9	hSpCas9	negative selection	4985719
18251288	18251310	17	-	27760321	HT29	viability after 22 days	TTCCACGGCAAGTTCTACGAGG	FLII	ENSG00000177731	-1.9362580776200091	[268,209]	[61,115,38]	-8	hSpCas9	negative selection	4985720
18251393	18251415	17	+	27760321	HT29	viability after 22 days	ACTCGGAGTAGTCAAGGCGGGG	FLII	ENSG00000177731	-1.8319724667244652	[591,461]	[189,135,186]	-8	hSpCas9	negative selection	4985721
18251767	18251789	17	-	27760321	HT29	viability after 22 days	TCGCAAGATGCGACTGCGGAGG	FLII	ENSG00000177731	-0.9549819022760586	[594,463]	[353,192,399]	-6	hSpCas9	negative selection	4985722
18252067	18252089	17	+	27760321	HT29	viability after 22 days	TCGATGTTGTACCACTCAGCGG	FLII	ENSG00000177731	-0.8422603671611328	[308,240]	[176,171,182]	-6	hSpCas9	negative selection	4985723
18250908	18250930	17	+	27760321	HT29	viability after 19 days	CGCAAGTTGACAGCGTGGATGG	FLII	ENSG00000177731	-3.0023635517598364	[487,380]	[76,59,50]	-8	hSpCas9	negative selection	5069182
18251288	18251310	17	-	27760321	HT29	viability after 19 days	TTCCACGGCAAGTTCTACGAGG	FLII	ENSG00000177731	-1.637336821898434	[268,209]	[57,35,163]	-7	hSpCas9	negative selection	5069183
18251393	18251415	17	+	27760321	HT29	viability after 19 days	ACTCGGAGTAGTCAAGGCGGGG	FLII	ENSG00000177731	-1.5701279396207677	[591,461]	[321,115,183]	-7	hSpCas9	negative selection	5069184
18251767	18251789	17	-	27760321	HT29	viability after 19 days	TCGCAAGATGCGACTGCGGAGG	FLII	ENSG00000177731	-1.2829441536474642	[594,463]	[265,281,201]	-7	hSpCas9	negative selection	5069185
18252067	18252089	17	+	27760321	HT29	viability after 19 days	TCGATGTTGTACCACTCAGCGG	FLII	ENSG00000177731	-1.7096665405858777	[308,240]	[111,26,148]	-7	hSpCas9	negative selection	5069186
18250908	18250930	17	+	27760321	HT29	viability after 16 days	CGCAAGTTGACAGCGTGGATGG	FLII	ENSG00000177731	-1.3418898053696353	[487,380]	[55,171,334]	-7	hSpCas9	negative selection	5152645
18251288	18251310	17	-	27760321	HT29	viability after 16 days	TTCCACGGCAAGTTCTACGAGG	FLII	ENSG00000177731	-0.49803795570708564	[268,209]	[88,252,215]	-5	hSpCas9	negative selection	5152646
18251393	18251415	17	+	27760321	HT29	viability after 16 days	ACTCGGAGTAGTCAAGGCGGGG	FLII	ENSG00000177731	-0.11341248664311787	[591,461]	[396,545,677]	-1	hSpCas9	negative selection	5152647
18251767	18251789	17	-	27760321	HT29	viability after 16 days	TCGCAAGATGCGACTGCGGAGG	FLII	ENSG00000177731	-0.8397983723943607	[594,463]	[607,140,274]	-6	hSpCas9	negative selection	5152648
18252067	18252089	17	+	27760321	HT29	viability after 16 days	TCGATGTTGTACCACTCAGCGG	FLII	ENSG00000177731	-0.8025109477232548	[308,240]	[280,177,79]	-6	hSpCas9	negative selection	5152649
18250908	18250930	17	+	27760321	HT29	viability after 13 days	CGCAAGTTGACAGCGTGGATGG	FLII	ENSG00000177731	-1.4096832569292521	[487,380]	[193,233,143]	-8	hSpCas9	negative selection	5236108
18251288	18251310	17	-	27760321	HT29	viability after 13 days	TTCCACGGCAAGTTCTACGAGG	FLII	ENSG00000177731	-0.147045711846843	[268,209]	[189,262,296]	-2	hSpCas9	negative selection	5236109
18251393	18251415	17	+	27760321	HT29	viability after 13 days	ACTCGGAGTAGTCAAGGCGGGG	FLII	ENSG00000177731	-0.5918486310728046	[591,461]	[245,646,328]	-6	hSpCas9	negative selection	5236110
18251767	18251789	17	-	27760321	HT29	viability after 13 days	TCGCAAGATGCGACTGCGGAGG	FLII	ENSG00000177731	-0.36905266458301456	[594,463]	[501,522,405]	-4	hSpCas9	negative selection	5236111
18252067	18252089	17	+	27760321	HT29	viability after 13 days	TCGATGTTGTACCACTCAGCGG	FLII	ENSG00000177731	-0.26190330663714234	[308,240]	[155,386,255]	-3	hSpCas9	negative selection	5236112
18250908	18250930	17	+	27760321	HT29	viability after 10 days	CGCAAGTTGACAGCGTGGATGG	FLII	ENSG00000177731	-0.8783776967406264	[487,380]	[268,320,295]	-7	hSpCas9	negative selection	5319571
18251288	18251310	17	-	27760321	HT29	viability after 10 days	TTCCACGGCAAGTTCTACGAGG	FLII	ENSG00000177731	-0.05682618103063386	[268,209]	[477,133,246]	0	hSpCas9	negative selection	5319572
18251393	18251415	17	+	27760321	HT29	viability after 10 days	ACTCGGAGTAGTCAAGGCGGGG	FLII	ENSG00000177731	-0.24639984175827384	[591,461]	[723,499,440]	-3	hSpCas9	negative selection	5319573
18251767	18251789	17	-	27760321	HT29	viability after 10 days	TCGCAAGATGCGACTGCGGAGG	FLII	ENSG00000177731	-0.433170870474863	[594,463]	[521,539,409]	-5	hSpCas9	negative selection	5319574
18252067	18252089	17	+	27760321	HT29	viability after 10 days	TCGATGTTGTACCACTCAGCGG	FLII	ENSG00000177731	-0.2098359351811826	[308,240]	[383,206,296]	-3	hSpCas9	negative selection	5319575
18250908	18250930	17	+	27760321	MOLM13	viability	CGCAAGTTGACAGCGTGGATGG	FLII	ENSG00000177731	-4.603821651856927	[579,487]	[0,21]	-9	hSpCas9	negative selection	5403034
18251288	18251310	17	-	27760321	MOLM13	viability	TTCCACGGCAAGTTCTACGAGG	FLII	ENSG00000177731	0.9275554676284294	[286,268]	[647,0]	6	hSpCas9	negative selection	5403035
18251393	18251415	17	+	27760321	MOLM13	viability	ACTCGGAGTAGTCAAGGCGGGG	FLII	ENSG00000177731	-1.6665721790455086	[669,591]	[105,116]	-7	hSpCas9	negative selection	5403036
18251767	18251789	17	-	27760321	MOLM13	viability	TCGCAAGATGCGACTGCGGAGG	FLII	ENSG00000177731	-1.0199508531841393	[572,594]	[273,68]	-6	hSpCas9	negative selection	5403037
18252067	18252089	17	+	27760321	MOLM13	viability	TCGATGTTGTACCACTCAGCGG	FLII	ENSG00000177731	0.7401116567580963	[351,308]	[124,468]	5	hSpCas9	negative selection	5403038
18258278	18258301	17	+	27661255	K562	viability	GCTTGGGCGTGTGACCTCAGAGG	FLII	ENSG00000177731	0.042831005641906866	[867,814]	[696,689]	1	dCas9-KRAB	negative selection	5480424
18258283	18258306	17	+	27661255	K562	viability	GGCGTGTGACCTCAGAGGGGCGG	FLII	ENSG00000177731	0.055537378270436075	[688,669]	[599,533]	2	dCas9-KRAB	negative selection	5480425
18258538	18258561	17	+	27661255	K562	viability	GAGCCGAGCGGGACAGGAAGCGG	FLII	ENSG00000177731	-0.8849554728722779	[1147,1050]	[491,462]	-8	dCas9-KRAB	negative selection	5480426
18258641	18258664	17	-	27661255	K562	viability	GTGCGTGGCGTGGACCTCAGCGG	FLII	ENSG00000177731	-0.10990634932882684	[906,700]	[646,555]	-4	dCas9-KRAB	negative selection	5480427
18256515	18256538	17	+	27260156	BXPC3	viability	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	-0.2758502784521317	[243]	[184,132,287,248]	-6	hSpCas9	negative selection	5543766
18256554	18256577	17	-	27260156	BXPC3	viability	AACAACCTGACCACGCTTCATGG	FLII	ENSG00000177731	0.5145679264986922	[1118]	[1567,1653,1516,1982]	9	hSpCas9	negative selection	5543767
18253390	18253413	17	+	27260156	BXPC3	viability	CCCGTCAAAGTCCAGCTTGTTGG	FLII	ENSG00000177731	0.33286906988715337	[549]	[639,604,772,914]	7	hSpCas9	negative selection	5543768
18253318	18253341	17	+	27260156	BXPC3	viability	GACCAGCTCCAGGTTGTTGTTGG	FLII	ENSG00000177731	0.056530074669856545	[322]	[234,395,372,416]	1	hSpCas9	negative selection	5608031
18254163	18254186	17	-	27260156	BXPC3	viability	CAGGCAGCTCCCAGCGATGACGG	FLII	ENSG00000177731	-0.9803769338808828	[346]	[191,163,134,250]	-9	hSpCas9	negative selection	5608032
18254082	18254105	17	+	27260156	BXPC3	viability	CGAGGTTGCTCAGACCCTCCAGG	FLII	ENSG00000177731	0.0041093324633447725	[837]	[889,961,820,820]	0	hSpCas9	negative selection	5608033
18256515	18256538	17	+	27260156	A673	viability	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	-0.2328075617672969	[243]	[295,172,282,251]	-5	hSpCas9	negative selection	5665017
18256554	18256577	17	-	27260156	A673	viability	AACAACCTGACCACGCTTCATGG	FLII	ENSG00000177731	0.4347726733750856	[1118]	[1990,1710,1844,1731]	8	hSpCas9	negative selection	5665018
18253390	18253413	17	+	27260156	A673	viability	CCCGTCAAAGTCCAGCTTGTTGG	FLII	ENSG00000177731	0.20727148245951685	[549]	[805,647,773,831]	5	hSpCas9	negative selection	5665019
18253318	18253341	17	+	27260156	A673	viability	GACCAGCTCCAGGTTGTTGTTGG	FLII	ENSG00000177731	-0.35839372201160824	[322]	[281,296,267,363]	-7	hSpCas9	negative selection	5729282
18254163	18254186	17	-	27260156	A673	viability	CAGGCAGCTCCCAGCGATGACGG	FLII	ENSG00000177731	-0.3224377805023813	[346]	[388,296,329,322]	-7	hSpCas9	negative selection	5729283
18254082	18254105	17	+	27260156	A673	viability	CGAGGTTGCTCAGACCCTCCAGG	FLII	ENSG00000177731	-0.3344152759132007	[837]	[782,755,828,822]	-7	hSpCas9	negative selection	5729284
18256515	18256538	17	+	27260156	A375	viability	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	-0.34653656788769704	[243]	[96,173,403,213]	-5	hSpCas9	negative selection	5786268
18256554	18256577	17	-	27260156	A375	viability	AACAACCTGACCACGCTTCATGG	FLII	ENSG00000177731	0.7342919639878218	[1118]	[2675,2530,1740,1834]	9	hSpCas9	negative selection	5786269
18253390	18253413	17	+	27260156	A375	viability	CCCGTCAAAGTCCAGCTTGTTGG	FLII	ENSG00000177731	0.36527620061060506	[549]	[599,884,916,901]	5	hSpCas9	negative selection	5786270
18253318	18253341	17	+	27260156	A375	viability	GACCAGCTCCAGGTTGTTGTTGG	FLII	ENSG00000177731	-1.05752272842241	[322]	[238,191,157,141]	-8	hSpCas9	negative selection	5850533
18254163	18254186	17	-	27260156	A375	viability	CAGGCAGCTCCCAGCGATGACGG	FLII	ENSG00000177731	-1.1413151278194125	[346]	[190,61,304,161]	-8	hSpCas9	negative selection	5850534
18254082	18254105	17	+	27260156	A375	viability	CGAGGTTGCTCAGACCCTCCAGG	FLII	ENSG00000177731	-0.07849490016073146	[837]	[725,1074,1232,714]	-1	hSpCas9	negative selection	5850535
18256515	18256538	17	+	27260156	COLO741	viability	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	0.26701998352123246	[243]	[414,380,334]	5	hSpCas9	negative selection	5907519
18256554	18256577	17	-	27260156	COLO741	viability	AACAACCTGACCACGCTTCATGG	FLII	ENSG00000177731	0.5656554762069501	[1118]	[2299,2000,2061]	9	hSpCas9	negative selection	5907520
18253390	18253413	17	+	27260156	COLO741	viability	CCCGTCAAAGTCCAGCTTGTTGG	FLII	ENSG00000177731	0.2254707019097095	[549]	[876,955,647]	5	hSpCas9	negative selection	5907521
18253318	18253341	17	+	27260156	COLO741	viability	GACCAGCTCCAGGTTGTTGTTGG	FLII	ENSG00000177731	0.018045473134600365	[322]	[374,369,497]	0	hSpCas9	negative selection	5971784
18254163	18254186	17	-	27260156	COLO741	viability	CAGGCAGCTCCCAGCGATGACGG	FLII	ENSG00000177731	-0.21549792396484962	[346]	[525,309,324]	-4	hSpCas9	negative selection	5971785
18254082	18254105	17	+	27260156	COLO741	viability	CGAGGTTGCTCAGACCCTCCAGG	FLII	ENSG00000177731	0.002578201336650987	[837]	[1188,1142,905]	0	hSpCas9	negative selection	5971786
18256515	18256538	17	+	27260156	CAL120	viability	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	-0.7046730544756692	[243]	[140,223,186]	-7	hSpCas9	negative selection	6028770
18256554	18256577	17	-	27260156	CAL120	viability	AACAACCTGACCACGCTTCATGG	FLII	ENSG00000177731	0.5475456894533324	[1118]	[2717,1757,1736]	7	hSpCas9	negative selection	6028771
18253390	18253413	17	+	27260156	CAL120	viability	CCCGTCAAAGTCCAGCTTGTTGG	FLII	ENSG00000177731	0.3291871337906376	[549]	[733,898,925]	5	hSpCas9	negative selection	6028772
18253318	18253341	17	+	27260156	CAL120	viability	GACCAGCTCCAGGTTGTTGTTGG	FLII	ENSG00000177731	-0.6895486815018751	[322]	[360,244,159]	-7	hSpCas9	negative selection	6093035
18254163	18254186	17	-	27260156	CAL120	viability	CAGGCAGCTCCCAGCGATGACGG	FLII	ENSG00000177731	-0.3260489383413972	[346]	[296,267,458]	-5	hSpCas9	negative selection	6093036
18254082	18254105	17	+	27260156	CAL120	viability	CGAGGTTGCTCAGACCCTCCAGG	FLII	ENSG00000177731	0.2328153441988513	[837]	[1902,1057,823]	3	hSpCas9	negative selection	6093037
18256515	18256538	17	+	27260156	CADOES1	viability	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	-0.4404649906926583	[243]	[128,179,167,192]	-6	hSpCas9	negative selection	6150021
18256554	18256577	17	-	27260156	CADOES1	viability	AACAACCTGACCACGCTTCATGG	FLII	ENSG00000177731	0.8189859534632518	[1118]	[2029,1916,1607,1786]	9	hSpCas9	negative selection	6150022
18253390	18253413	17	+	27260156	CADOES1	viability	CCCGTCAAAGTCCAGCTTGTTGG	FLII	ENSG00000177731	0.44209221560057843	[549]	[635,517,867,759]	7	hSpCas9	negative selection	6150023
18253318	18253341	17	+	27260156	CADOES1	viability	GACCAGCTCCAGGTTGTTGTTGG	FLII	ENSG00000177731	0.16149534153346645	[322]	[388,239,317,398]	2	hSpCas9	negative selection	6214286
18254163	18254186	17	-	27260156	CADOES1	viability	CAGGCAGCTCCCAGCGATGACGG	FLII	ENSG00000177731	-0.36691168166533245	[346]	[269,268,237,222]	-6	hSpCas9	negative selection	6214287
18254082	18254105	17	+	27260156	CADOES1	viability	CGAGGTTGCTCAGACCCTCCAGG	FLII	ENSG00000177731	-0.016631920454209137	[837]	[853,824,625,776]	0	hSpCas9	negative selection	6214288
18256515	18256538	17	+	27260156	EWS502	viability	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	-0.25671519745603466	[243]	[169,196,140,372]	-4	hSpCas9	negative selection	6271272
18256554	18256577	17	-	27260156	EWS502	viability	AACAACCTGACCACGCTTCATGG	FLII	ENSG00000177731	0.7415266352984959	[1118]	[1868,1820,2303,1946]	9	hSpCas9	negative selection	6271273
18253390	18253413	17	+	27260156	EWS502	viability	CCCGTCAAAGTCCAGCTTGTTGG	FLII	ENSG00000177731	0.3731308837348749	[549]	[531,743,711,1076]	6	hSpCas9	negative selection	6271274
18253318	18253341	17	+	27260156	EWS502	viability	GACCAGCTCCAGGTTGTTGTTGG	FLII	ENSG00000177731	-0.12823408325500085	[322]	[345,272,308,320]	-2	hSpCas9	negative selection	6335537
18254163	18254186	17	-	27260156	EWS502	viability	CAGGCAGCTCCCAGCGATGACGG	FLII	ENSG00000177731	-0.3769735593430487	[346]	[182,270,413,276]	-6	hSpCas9	negative selection	6335538
18254082	18254105	17	+	27260156	EWS502	viability	CGAGGTTGCTCAGACCCTCCAGG	FLII	ENSG00000177731	-0.045649313490511934	[837]	[718,863,1116,748]	-1	hSpCas9	negative selection	6335539
18256515	18256538	17	+	27260156	EW8	viability	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	-0.3174078357130563	[243]	[145,247,143,97]	-5	hSpCas9	negative selection	6392523
18256554	18256577	17	-	27260156	EW8	viability	AACAACCTGACCACGCTTCATGG	FLII	ENSG00000177731	0.4591411912930181	[1118]	[1246,1306,1279,1143]	7	hSpCas9	negative selection	6392524
18253390	18253413	17	+	27260156	EW8	viability	CCCGTCAAAGTCCAGCTTGTTGG	FLII	ENSG00000177731	0.07953763978675024	[549]	[458,612,292,546]	1	hSpCas9	negative selection	6392525
18253318	18253341	17	+	27260156	EW8	viability	GACCAGCTCCAGGTTGTTGTTGG	FLII	ENSG00000177731	-0.0526912733805498	[322]	[163,249,280,298]	-1	hSpCas9	negative selection	6456788
18254163	18254186	17	-	27260156	EW8	viability	CAGGCAGCTCCCAGCGATGACGG	FLII	ENSG00000177731	-0.5704202428937848	[346]	[302,123,142,206]	-8	hSpCas9	negative selection	6456789
18254082	18254105	17	+	27260156	EW8	viability	CGAGGTTGCTCAGACCCTCCAGG	FLII	ENSG00000177731	-0.16183753582425608	[837]	[578,608,506,744]	-3	hSpCas9	negative selection	6456790
18256515	18256538	17	+	27260156	CORL105	viability	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	-0.127347691748539	[243]	[268,147,248,379]	-2	hSpCas9	negative selection	6513774
18256554	18256577	17	-	27260156	CORL105	viability	AACAACCTGACCACGCTTCATGG	FLII	ENSG00000177731	0.5955202484898376	[1118]	[2049,1817,2121,1954]	9	hSpCas9	negative selection	6513775
18253390	18253413	17	+	27260156	CORL105	viability	CCCGTCAAAGTCCAGCTTGTTGG	FLII	ENSG00000177731	0.05391785697057214	[549]	[812,592,592,668]	1	hSpCas9	negative selection	6513776
18253318	18253341	17	+	27260156	CORL105	viability	GACCAGCTCCAGGTTGTTGTTGG	FLII	ENSG00000177731	0.23570163298675723	[322]	[521,537,486,241]	4	hSpCas9	negative selection	6578039
18254163	18254186	17	-	27260156	CORL105	viability	CAGGCAGCTCCCAGCGATGACGG	FLII	ENSG00000177731	-0.28663702448262357	[346]	[238,364,314,405]	-5	hSpCas9	negative selection	6578040
18254082	18254105	17	+	27260156	CORL105	viability	CGAGGTTGCTCAGACCCTCCAGG	FLII	ENSG00000177731	-0.20291922891014746	[837]	[809,956,747,873]	-4	hSpCas9	negative selection	6578041
18256515	18256538	17	+	27260156	HS294T	viability	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	0.7052161384554333	[243]	[47,88,152,373]	8	hSpCas9	negative selection	6635025
18256554	18256577	17	-	27260156	HS294T	viability	AACAACCTGACCACGCTTCATGG	FLII	ENSG00000177731	0.9043756764366366	[1118]	[702,752,817,1007]	9	hSpCas9	negative selection	6635026
18253390	18253413	17	+	27260156	HS294T	viability	CCCGTCAAAGTCCAGCTTGTTGG	FLII	ENSG00000177731	-0.0015012466969606675	[549]	[172,172,186,342]	0	hSpCas9	negative selection	6635027
18253318	18253341	17	+	27260156	HS294T	viability	GACCAGCTCCAGGTTGTTGTTGG	FLII	ENSG00000177731	0.38578943945424493	[322]	[133,171,118,242]	5	hSpCas9	negative selection	6699290
18254163	18254186	17	-	27260156	HS294T	viability	CAGGCAGCTCCCAGCGATGACGG	FLII	ENSG00000177731	-0.46871687785449995	[346]	[49,64,86,209]	-6	hSpCas9	negative selection	6699291
18254082	18254105	17	+	27260156	HS294T	viability	CGAGGTTGCTCAGACCCTCCAGG	FLII	ENSG00000177731	-0.2392116182814108	[837]	[277,211,248,376]	-3	hSpCas9	negative selection	6699292
18256515	18256538	17	+	27260156	HCC44	viability	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	0.20763586264879763	[243]	[516,276,320,185]	3	hSpCas9	negative selection	6756276
18256554	18256577	17	-	27260156	HCC44	viability	AACAACCTGACCACGCTTCATGG	FLII	ENSG00000177731	0.47993257098243847	[1118]	[1858,1502,2104,1685]	7	hSpCas9	negative selection	6756277
18253390	18253413	17	+	27260156	HCC44	viability	CCCGTCAAAGTCCAGCTTGTTGG	FLII	ENSG00000177731	0.4012077654013534	[549]	[863,559,875,1022]	6	hSpCas9	negative selection	6756278
18253318	18253341	17	+	27260156	HCC44	viability	GACCAGCTCCAGGTTGTTGTTGG	FLII	ENSG00000177731	0.2787722135064232	[322]	[529,409,657,227]	4	hSpCas9	negative selection	6820541
18254163	18254186	17	-	27260156	HCC44	viability	CAGGCAGCTCCCAGCGATGACGG	FLII	ENSG00000177731	0.04431163785774467	[346]	[511,307,390,424]	0	hSpCas9	negative selection	6820542
18254082	18254105	17	+	27260156	HCC44	viability	CGAGGTTGCTCAGACCCTCCAGG	FLII	ENSG00000177731	0.3077790177847476	[837]	[1215,1224,982,1220]	5	hSpCas9	negative selection	6820543
18256515	18256538	17	+	27260156	G402	viability	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	-0.703006744594137	[243]	[323,81,190,149]	-7	hSpCas9	negative selection	6877527
18256554	18256577	17	-	27260156	G402	viability	AACAACCTGACCACGCTTCATGG	FLII	ENSG00000177731	0.8069210056135658	[1118]	[1818,1994,2463,3125]	8	hSpCas9	negative selection	6877528
18253390	18253413	17	+	27260156	G402	viability	CCCGTCAAAGTCCAGCTTGTTGG	FLII	ENSG00000177731	0.31837662146731294	[549]	[872,918,702,857]	4	hSpCas9	negative selection	6877529
18253318	18253341	17	+	27260156	G402	viability	GACCAGCTCCAGGTTGTTGTTGG	FLII	ENSG00000177731	-0.2508290141830064	[322]	[359,200,253,496]	-3	hSpCas9	negative selection	6941792
18254163	18254186	17	-	27260156	G402	viability	CAGGCAGCTCCCAGCGATGACGG	FLII	ENSG00000177731	-0.8155987195341856	[346]	[549,82,231,136]	-7	hSpCas9	negative selection	6941793
18254082	18254105	17	+	27260156	G402	viability	CGAGGTTGCTCAGACCCTCCAGG	FLII	ENSG00000177731	-0.23434649076619474	[837]	[1376,553,886,717]	-3	hSpCas9	negative selection	6941794
18256515	18256538	17	+	27260156	L33	viability	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	0.1149440361952967	[243]	[368,63,165,264]	2	hSpCas9	negative selection	6998778
18256554	18256577	17	-	27260156	L33	viability	AACAACCTGACCACGCTTCATGG	FLII	ENSG00000177731	0.591362191537619	[1118]	[1659,698,1071,1672]	9	hSpCas9	negative selection	6998779
18253390	18253413	17	+	27260156	L33	viability	CCCGTCAAAGTCCAGCTTGTTGG	FLII	ENSG00000177731	0.4021420713877383	[549]	[664,269,564,686]	8	hSpCas9	negative selection	6998780
18253318	18253341	17	+	27260156	L33	viability	GACCAGCTCCAGGTTGTTGTTGG	FLII	ENSG00000177731	0.008372357895868765	[322]	[429,114,170,313]	0	hSpCas9	negative selection	7063043
18254163	18254186	17	-	27260156	L33	viability	CAGGCAGCTCCCAGCGATGACGG	FLII	ENSG00000177731	-0.46818083716296227	[346]	[203,77,153,363]	-8	hSpCas9	negative selection	7063044
18254082	18254105	17	+	27260156	L33	viability	CGAGGTTGCTCAGACCCTCCAGG	FLII	ENSG00000177731	-0.14348928609548328	[837]	[760,331,430,776]	-3	hSpCas9	negative selection	7063045
18256515	18256538	17	+	27260156	K562	viability	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	-0.7974595702482086	[243]	[147,136,124,93]	-7	hSpCas9	negative selection	7120029
18256554	18256577	17	-	27260156	K562	viability	AACAACCTGACCACGCTTCATGG	FLII	ENSG00000177731	0.856670546207406	[1118]	[2069,1448,2077,1613]	9	hSpCas9	negative selection	7120030
18253390	18253413	17	+	27260156	K562	viability	CCCGTCAAAGTCCAGCTTGTTGG	FLII	ENSG00000177731	0.5981228633751736	[549]	[676,729,1086,482]	7	hSpCas9	negative selection	7120031
18253318	18253341	17	+	27260156	K562	viability	GACCAGCTCCAGGTTGTTGTTGG	FLII	ENSG00000177731	-0.4556317830796991	[322]	[270,207,140,218]	-5	hSpCas9	negative selection	7184294
18254163	18254186	17	-	27260156	K562	viability	CAGGCAGCTCCCAGCGATGACGG	FLII	ENSG00000177731	-0.8454879698228637	[346]	[59,183,191,232]	-7	hSpCas9	negative selection	7184295
18254082	18254105	17	+	27260156	K562	viability	CGAGGTTGCTCAGACCCTCCAGG	FLII	ENSG00000177731	-0.11724344260404085	[837]	[679,591,840,627]	-1	hSpCas9	negative selection	7184296
18256515	18256538	17	+	27260156	HT29	viability	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	-0.2962919301951594	[243]	[207,377,212,181]	-5	hSpCas9	negative selection	7241280
18256554	18256577	17	-	27260156	HT29	viability	AACAACCTGACCACGCTTCATGG	FLII	ENSG00000177731	0.4119515831780476	[1118]	[2102,2053,1925,1255]	7	hSpCas9	negative selection	7241281
18253390	18253413	17	+	27260156	HT29	viability	CCCGTCAAAGTCCAGCTTGTTGG	FLII	ENSG00000177731	0.42629582051275994	[549]	[1069,735,967,821]	8	hSpCas9	negative selection	7241282
18253318	18253341	17	+	27260156	HT29	viability	GACCAGCTCCAGGTTGTTGTTGG	FLII	ENSG00000177731	-0.34792398263166213	[322]	[260,266,400,296]	-6	hSpCas9	negative selection	7305545
18254163	18254186	17	-	27260156	HT29	viability	CAGGCAGCTCCCAGCGATGACGG	FLII	ENSG00000177731	-0.8367497728912334	[346]	[241,259,220,223]	-8	hSpCas9	negative selection	7305546
18254082	18254105	17	+	27260156	HT29	viability	CGAGGTTGCTCAGACCCTCCAGG	FLII	ENSG00000177731	-0.11754552646499505	[837]	[1048,879,1050,790]	-2	hSpCas9	negative selection	7305547
18256515	18256538	17	+	27260156	MHHES1	viability	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	-0.5515371475739117	[243]	[228,146,134,225]	-8	hSpCas9	negative selection	7362531
18256554	18256577	17	-	27260156	MHHES1	viability	AACAACCTGACCACGCTTCATGG	FLII	ENSG00000177731	0.5399713481512625	[1118]	[2494,2163,1720,1175]	8	hSpCas9	negative selection	7362532
18253390	18253413	17	+	27260156	MHHES1	viability	CCCGTCAAAGTCCAGCTTGTTGG	FLII	ENSG00000177731	0.09792536805065863	[549]	[488,790,819,554]	1	hSpCas9	negative selection	7362533
18253318	18253341	17	+	27260156	MHHES1	viability	GACCAGCTCCAGGTTGTTGTTGG	FLII	ENSG00000177731	-1.0407054667112376	[322]	[214,280,112,121]	-9	hSpCas9	negative selection	7426796
18254163	18254186	17	-	27260156	MHHES1	viability	CAGGCAGCTCCCAGCGATGACGG	FLII	ENSG00000177731	-0.41734226674003266	[346]	[376,421,226,185]	-7	hSpCas9	negative selection	7426797
18254082	18254105	17	+	27260156	MHHES1	viability	CGAGGTTGCTCAGACCCTCCAGG	FLII	ENSG00000177731	0.0041759164985536446	[837]	[1147,1412,740,611]	0	hSpCas9	negative selection	7426798
18256515	18256538	17	+	27260156	MEWO	viability	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	-0.1536270405653024	[243]	[216,182,217]	-3	hSpCas9	negative selection	7483782
18256554	18256577	17	-	27260156	MEWO	viability	AACAACCTGACCACGCTTCATGG	FLII	ENSG00000177731	0.36517407479789576	[1118]	[1829,1206,1101]	7	hSpCas9	negative selection	7483783
18253390	18253413	17	+	27260156	MEWO	viability	CCCGTCAAAGTCCAGCTTGTTGG	FLII	ENSG00000177731	0.5622058106409753	[549]	[754,797,724]	9	hSpCas9	negative selection	7483784
18253318	18253341	17	+	27260156	MEWO	viability	GACCAGCTCCAGGTTGTTGTTGG	FLII	ENSG00000177731	0.09812888934564074	[322]	[265,356,335]	2	hSpCas9	negative selection	7548047
18254163	18254186	17	-	27260156	MEWO	viability	CAGGCAGCTCCCAGCGATGACGG	FLII	ENSG00000177731	-0.2935429232925743	[346]	[357,182,271]	-6	hSpCas9	negative selection	7548048
18254082	18254105	17	+	27260156	MEWO	viability	CGAGGTTGCTCAGACCCTCCAGG	FLII	ENSG00000177731	-0.34980284119126764	[837]	[633,635,578]	-6	hSpCas9	negative selection	7548049
18256515	18256538	17	+	27260156	LNCAPCLONEFGC	viability	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	-0.32189607622651173	[243]	[254,118,186,149]	-5	hSpCas9	negative selection	7605033
18256554	18256577	17	-	27260156	LNCAPCLONEFGC	viability	AACAACCTGACCACGCTTCATGG	FLII	ENSG00000177731	0.8279569252438088	[1118]	[1326,1792,2533,1660]	9	hSpCas9	negative selection	7605034
18253390	18253413	17	+	27260156	LNCAPCLONEFGC	viability	CCCGTCAAAGTCCAGCTTGTTGG	FLII	ENSG00000177731	-0.6613559811701004	[549]	[276,256,392,348]	-7	hSpCas9	negative selection	7605035
18253318	18253341	17	+	27260156	LNCAPCLONEFGC	viability	GACCAGCTCCAGGTTGTTGTTGG	FLII	ENSG00000177731	-0.40281702548303955	[322]	[109,226,302,258]	-6	hSpCas9	negative selection	7669298
18254163	18254186	17	-	27260156	LNCAPCLONEFGC	viability	CAGGCAGCTCCCAGCGATGACGG	FLII	ENSG00000177731	-0.36938857551598986	[346]	[177,293,343,169]	-5	hSpCas9	negative selection	7669299
18254082	18254105	17	+	27260156	LNCAPCLONEFGC	viability	CGAGGTTGCTCAGACCCTCCAGG	FLII	ENSG00000177731	-0.06726674157934265	[837]	[731,732,859,591]	-1	hSpCas9	negative selection	7669300
18256515	18256538	17	+	27260156	PANC0327	viability	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	-0.7666042210507509	[243]	[61,213,101,114]	-8	hSpCas9	negative selection	7726284
18256554	18256577	17	-	27260156	PANC0327	viability	AACAACCTGACCACGCTTCATGG	FLII	ENSG00000177731	0.7921135253697849	[1118]	[2037,1313,1336,2272]	9	hSpCas9	negative selection	7726285
18253390	18253413	17	+	27260156	PANC0327	viability	CCCGTCAAAGTCCAGCTTGTTGG	FLII	ENSG00000177731	0.64281754552733	[549]	[1021,564,791,718]	8	hSpCas9	negative selection	7726286
18253318	18253341	17	+	27260156	PANC0327	viability	GACCAGCTCCAGGTTGTTGTTGG	FLII	ENSG00000177731	-1.13603520358823	[322]	[180,117,151,76]	-8	hSpCas9	negative selection	7790549
18254163	18254186	17	-	27260156	PANC0327	viability	CAGGCAGCTCCCAGCGATGACGG	FLII	ENSG00000177731	-1.0782809492635008	[346]	[189,188,146,55]	-8	hSpCas9	negative selection	7790550
18254082	18254105	17	+	27260156	PANC0327	viability	CGAGGTTGCTCAGACCCTCCAGG	FLII	ENSG00000177731	-0.3763137163162826	[837]	[944,395,464,540]	-5	hSpCas9	negative selection	7790551
18256515	18256538	17	+	27260156	NCIH2009	viability	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	-0.9134767987446717	[243]	[167,185,185]	-8	hSpCas9	negative selection	7847535
18256554	18256577	17	-	27260156	NCIH2009	viability	AACAACCTGACCACGCTTCATGG	FLII	ENSG00000177731	0.8314257524612201	[1118]	[3364,2591,2502]	9	hSpCas9	negative selection	7847536
18253390	18253413	17	+	27260156	NCIH2009	viability	CCCGTCAAAGTCCAGCTTGTTGG	FLII	ENSG00000177731	0.219744630301327	[549]	[1185,873,680]	3	hSpCas9	negative selection	7847537
18253318	18253341	17	+	27260156	NCIH2009	viability	GACCAGCTCCAGGTTGTTGTTGG	FLII	ENSG00000177731	-0.6599719880949476	[322]	[348,278,240]	-7	hSpCas9	negative selection	7911800
18254163	18254186	17	-	27260156	NCIH2009	viability	CAGGCAGCTCCCAGCGATGACGG	FLII	ENSG00000177731	-1.1643859976311226	[346]	[374,155,149]	-8	hSpCas9	negative selection	7911801
18254082	18254105	17	+	27260156	NCIH2009	viability	CGAGGTTGCTCAGACCCTCCAGG	FLII	ENSG00000177731	-0.18979901232772667	[837]	[1264,963,896]	-3	hSpCas9	negative selection	7911802
18256515	18256538	17	+	27260156	NCIH1373	viability	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	-1.147469609484408	[243]	[109,226,57,21]	-8	hSpCas9	negative selection	7968786
18256554	18256577	17	-	27260156	NCIH1373	viability	AACAACCTGACCACGCTTCATGG	FLII	ENSG00000177731	1.1165229321651868	[1118]	[1655,2416,3791,748]	9	hSpCas9	negative selection	7968787
18253390	18253413	17	+	27260156	NCIH1373	viability	CCCGTCAAAGTCCAGCTTGTTGG	FLII	ENSG00000177731	0.16765532051659995	[549]	[857,596,595,198]	1	hSpCas9	negative selection	7968788
18253318	18253341	17	+	27260156	NCIH1373	viability	GACCAGCTCCAGGTTGTTGTTGG	FLII	ENSG00000177731	-0.605942876911442	[322]	[522,65,164,68]	-6	hSpCas9	negative selection	8033051
18254163	18254186	17	-	27260156	NCIH1373	viability	CAGGCAGCTCCCAGCGATGACGG	FLII	ENSG00000177731	-0.5870240257966113	[346]	[347,200,309,49]	-5	hSpCas9	negative selection	8033052
18254082	18254105	17	+	27260156	NCIH1373	viability	CGAGGTTGCTCAGACCCTCCAGG	FLII	ENSG00000177731	-0.13227995683148763	[837]	[1602,505,694,202]	-1	hSpCas9	negative selection	8033053
18256515	18256538	17	+	27260156	PATU8902	viability	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	-1.8374243183048606	[243]	[153,32,89,103]	-9	hSpCas9	negative selection	8090037
18256554	18256577	17	-	27260156	PATU8902	viability	AACAACCTGACCACGCTTCATGG	FLII	ENSG00000177731	1.1308806691824727	[1118]	[3953,3783,2202,4069]	9	hSpCas9	negative selection	8090038
18253390	18253413	17	+	27260156	PATU8902	viability	CCCGTCAAAGTCCAGCTTGTTGG	FLII	ENSG00000177731	-1.0023401331090038	[549]	[429,463,437,151]	-7	hSpCas9	negative selection	8090039
18253318	18253341	17	+	27260156	PATU8902	viability	GACCAGCTCCAGGTTGTTGTTGG	FLII	ENSG00000177731	-1.0519225825817493	[322]	[332,155,217,148]	-7	hSpCas9	negative selection	8154302
18254163	18254186	17	-	27260156	PATU8902	viability	CAGGCAGCTCCCAGCGATGACGG	FLII	ENSG00000177731	-1.7062215483097813	[346]	[98,202,78,239]	-8	hSpCas9	negative selection	8154303
18254082	18254105	17	+	27260156	PATU8902	viability	CGAGGTTGCTCAGACCCTCCAGG	FLII	ENSG00000177731	0.09364346560390713	[837]	[1070,1363,935,1742]	0	hSpCas9	negative selection	8154304
18256515	18256538	17	+	27260156	PANC1	viability	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	-1.1336706847458058	[243]	[74,228,56,53]	-8	hSpCas9	negative selection	8211288
18256554	18256577	17	-	27260156	PANC1	viability	AACAACCTGACCACGCTTCATGG	FLII	ENSG00000177731	0.6894995082754083	[1118]	[1481,1776,1828,1195]	9	hSpCas9	negative selection	8211289
18253390	18253413	17	+	27260156	PANC1	viability	CCCGTCAAAGTCCAGCTTGTTGG	FLII	ENSG00000177731	-0.6169094125190392	[549]	[230,425,282,311]	-7	hSpCas9	negative selection	8211290
18253318	18253341	17	+	27260156	PANC1	viability	GACCAGCTCCAGGTTGTTGTTGG	FLII	ENSG00000177731	-1.3606258467168981	[322]	[75,152,147,69]	-9	hSpCas9	negative selection	8275553
18254163	18254186	17	-	27260156	PANC1	viability	CAGGCAGCTCCCAGCGATGACGG	FLII	ENSG00000177731	-2.057874565789715	[346]	[67,83,52,80]	-9	hSpCas9	negative selection	8275554
18254082	18254105	17	+	27260156	PANC1	viability	CGAGGTTGCTCAGACCCTCCAGG	FLII	ENSG00000177731	-0.3085074869436567	[837]	[443,710,734,473]	-5	hSpCas9	negative selection	8275555
18256515	18256538	17	+	27260156	PANC0813	viability	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	-0.9743415943175937	[243]	[241,147,94,108]	-8	hSpCas9	negative selection	8332539
18256554	18256577	17	-	27260156	PANC0813	viability	AACAACCTGACCACGCTTCATGG	FLII	ENSG00000177731	0.8196273390648201	[1118]	[2449,2025,2479,2331]	9	hSpCas9	negative selection	8332540
18253390	18253413	17	+	27260156	PANC0813	viability	CCCGTCAAAGTCCAGCTTGTTGG	FLII	ENSG00000177731	0.17681524995154238	[549]	[933,793,538,673]	3	hSpCas9	negative selection	8332541
18253318	18253341	17	+	27260156	PANC0813	viability	GACCAGCTCCAGGTTGTTGTTGG	FLII	ENSG00000177731	-1.0497627389128152	[322]	[296,169,111,164]	-8	hSpCas9	negative selection	8396804
18254163	18254186	17	-	27260156	PANC0813	viability	CAGGCAGCTCCCAGCGATGACGG	FLII	ENSG00000177731	-0.795109867174715	[346]	[239,202,281,215]	-8	hSpCas9	negative selection	8396805
18254082	18254105	17	+	27260156	PANC0813	viability	CGAGGTTGCTCAGACCCTCCAGG	FLII	ENSG00000177731	-0.29679791189017446	[837]	[1028,812,667,718]	-5	hSpCas9	negative selection	8396806
18256515	18256538	17	+	27260156	RDES	viability	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	-0.16034300864561568	[243]	[212,269,271,247]	-3	hSpCas9	negative selection	8453790
18256554	18256577	17	-	27260156	RDES	viability	AACAACCTGACCACGCTTCATGG	FLII	ENSG00000177731	0.7556425471066397	[1118]	[1871,1845,2592,2470]	9	hSpCas9	negative selection	8453791
18253390	18253413	17	+	27260156	RDES	viability	CCCGTCAAAGTCCAGCTTGTTGG	FLII	ENSG00000177731	0.3057315283402138	[549]	[560,757,769,1116]	5	hSpCas9	negative selection	8453792
18253318	18253341	17	+	27260156	RDES	viability	GACCAGCTCCAGGTTGTTGTTGG	FLII	ENSG00000177731	-0.3286237258897582	[322]	[299,284,355,222]	-5	hSpCas9	negative selection	8518055
18254163	18254186	17	-	27260156	RDES	viability	CAGGCAGCTCCCAGCGATGACGG	FLII	ENSG00000177731	-0.8724864779724706	[346]	[167,222,213,279]	-9	hSpCas9	negative selection	8518056
18254082	18254105	17	+	27260156	RDES	viability	CGAGGTTGCTCAGACCCTCCAGG	FLII	ENSG00000177731	-0.13537201258808285	[837]	[836,706,845,1157]	-2	hSpCas9	negative selection	8518057
18256515	18256538	17	+	27260156	PC3	viability	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	-0.8183175087789047	[243]	[80,189,225,95]	-9	hSpCas9	negative selection	8575041
18256554	18256577	17	-	27260156	PC3	viability	AACAACCTGACCACGCTTCATGG	FLII	ENSG00000177731	0.34351318414672827	[1118]	[712,1436,2397,1700]	7	hSpCas9	negative selection	8575042
18253390	18253413	17	+	27260156	PC3	viability	CCCGTCAAAGTCCAGCTTGTTGG	FLII	ENSG00000177731	0.48421937554668426	[549]	[547,651,1248,827]	8	hSpCas9	negative selection	8575043
18253318	18253341	17	+	27260156	PC3	viability	GACCAGCTCCAGGTTGTTGTTGG	FLII	ENSG00000177731	-0.13463330392665618	[322]	[210,263,574,235]	-3	hSpCas9	negative selection	8639306
18254163	18254186	17	-	27260156	PC3	viability	CAGGCAGCTCCCAGCGATGACGG	FLII	ENSG00000177731	-0.3509695459474485	[346]	[123,412,291,299]	-7	hSpCas9	negative selection	8639307
18254082	18254105	17	+	27260156	PC3	viability	CGAGGTTGCTCAGACCCTCCAGG	FLII	ENSG00000177731	-0.16931561967044118	[837]	[431,764,1068,905]	-4	hSpCas9	negative selection	8639308
18256515	18256538	17	+	27260156	PATU8988T	viability	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	-0.539483372802209	[243]	[84,166,275,115]	-7	hSpCas9	negative selection	8696292
18256554	18256577	17	-	27260156	PATU8988T	viability	AACAACCTGACCACGCTTCATGG	FLII	ENSG00000177731	0.5925029648970477	[1118]	[1301,1865,1634,1749]	8	hSpCas9	negative selection	8696293
18253390	18253413	17	+	27260156	PATU8988T	viability	CCCGTCAAAGTCCAGCTTGTTGG	FLII	ENSG00000177731	0.18730527563039132	[549]	[585,696,423,734]	3	hSpCas9	negative selection	8696294
18253318	18253341	17	+	27260156	PATU8988T	viability	GACCAGCTCCAGGTTGTTGTTGG	FLII	ENSG00000177731	-0.6364546919547144	[322]	[175,275,164,192]	-7	hSpCas9	negative selection	8760557
18254163	18254186	17	-	27260156	PATU8988T	viability	CAGGCAGCTCCCAGCGATGACGG	FLII	ENSG00000177731	-0.2134739969729555	[346]	[337,96,529,159]	-4	hSpCas9	negative selection	8760558
18254082	18254105	17	+	27260156	PATU8988T	viability	CGAGGTTGCTCAGACCCTCCAGG	FLII	ENSG00000177731	-0.6191329854134591	[837]	[357,633,497,637]	-7	hSpCas9	negative selection	8760559
18256515	18256538	17	+	27260156	T47D	viability	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	-0.23731376471409305	[243]	[229,200,316,217]	-5	hSpCas9	negative selection	8817543
18256554	18256577	17	-	27260156	T47D	viability	AACAACCTGACCACGCTTCATGG	FLII	ENSG00000177731	0.3944676407262251	[1118]	[1844,1609,1643,1766]	8	hSpCas9	negative selection	8817544
18253390	18253413	17	+	27260156	T47D	viability	CCCGTCAAAGTCCAGCTTGTTGG	FLII	ENSG00000177731	0.14221932452497185	[549]	[735,575,697,833]	3	hSpCas9	negative selection	8817545
18253318	18253341	17	+	27260156	T47D	viability	GACCAGCTCCAGGTTGTTGTTGG	FLII	ENSG00000177731	0.0559942477835883	[322]	[312,425,320,505]	1	hSpCas9	negative selection	8881808
18254163	18254186	17	-	27260156	T47D	viability	CAGGCAGCTCCCAGCGATGACGG	FLII	ENSG00000177731	-0.5139356613716284	[346]	[402,209,259,265]	-8	hSpCas9	negative selection	8881809
18254082	18254105	17	+	27260156	T47D	viability	CGAGGTTGCTCAGACCCTCCAGG	FLII	ENSG00000177731	-0.10762141002574965	[837]	[934,845,876,973]	-2	hSpCas9	negative selection	8881810
18256515	18256538	17	+	27260156	SU8686	viability	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	0.4418892877416102	[243]	[351,232,335,414]	7	hSpCas9	negative selection	8938794
18256554	18256577	17	-	27260156	SU8686	viability	AACAACCTGACCACGCTTCATGG	FLII	ENSG00000177731	0.7737211663205519	[1118]	[1675,1788,1999,2198]	9	hSpCas9	negative selection	8938795
18253390	18253413	17	+	27260156	SU8686	viability	CCCGTCAAAGTCCAGCTTGTTGG	FLII	ENSG00000177731	0.4673721939939137	[549]	[763,715,795,735]	7	hSpCas9	negative selection	8938796
18253318	18253341	17	+	27260156	SU8686	viability	GACCAGCTCCAGGTTGTTGTTGG	FLII	ENSG00000177731	0.1758352109477065	[322]	[379,432,247,369]	3	hSpCas9	negative selection	9003059
18254163	18254186	17	-	27260156	SU8686	viability	CAGGCAGCTCCCAGCGATGACGG	FLII	ENSG00000177731	-0.1191129045007831	[346]	[282,335,270,385]	-2	hSpCas9	negative selection	9003060
18254082	18254105	17	+	27260156	SU8686	viability	CGAGGTTGCTCAGACCCTCCAGG	FLII	ENSG00000177731	-0.1182278257068552	[837]	[741,725,842,752]	-2	hSpCas9	negative selection	9003061
18256515	18256538	17	+	27260156	SKES1	viability	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	-0.6584635407905011	[243]	[120,155,184,148]	-8	hSpCas9	negative selection	9060045
18256554	18256577	17	-	27260156	SKES1	viability	AACAACCTGACCACGCTTCATGG	FLII	ENSG00000177731	0.45280874607302923	[1118]	[1881,1363,1345,1533]	8	hSpCas9	negative selection	9060046
18253390	18253413	17	+	27260156	SKES1	viability	CCCGTCAAAGTCCAGCTTGTTGG	FLII	ENSG00000177731	0.3878943931382477	[549]	[898,730,628,641]	7	hSpCas9	negative selection	9060047
18253318	18253341	17	+	27260156	SKES1	viability	GACCAGCTCCAGGTTGTTGTTGG	FLII	ENSG00000177731	-0.04733866234801831	[322]	[379,315,332,233]	-1	hSpCas9	negative selection	9124310
18254163	18254186	17	-	27260156	SKES1	viability	CAGGCAGCTCCCAGCGATGACGG	FLII	ENSG00000177731	-0.3647001596321861	[346]	[402,304,209,187]	-7	hSpCas9	negative selection	9124311
18254082	18254105	17	+	27260156	SKES1	viability	CGAGGTTGCTCAGACCCTCCAGG	FLII	ENSG00000177731	-0.0741378334778936	[837]	[684,815,636,994]	-2	hSpCas9	negative selection	9124312
18256515	18256538	17	+	27260156	TOV112D	viability	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	-0.26410787297578353	[243]	[215,175,250,165]	-5	hSpCas9	negative selection	9181296
18256554	18256577	17	-	27260156	TOV112D	viability	AACAACCTGACCACGCTTCATGG	FLII	ENSG00000177731	0.4943159780890307	[1118]	[1988,1357,1601,1349]	8	hSpCas9	negative selection	9181297
18253390	18253413	17	+	27260156	TOV112D	viability	CCCGTCAAAGTCCAGCTTGTTGG	FLII	ENSG00000177731	0.270843806844543	[549]	[672,836,544,645]	5	hSpCas9	negative selection	9181298
18253318	18253341	17	+	27260156	TOV112D	viability	GACCAGCTCCAGGTTGTTGTTGG	FLII	ENSG00000177731	0.009603940288061441	[322]	[391,408,302,226]	0	hSpCas9	negative selection	9245561
18254163	18254186	17	-	27260156	TOV112D	viability	CAGGCAGCTCCCAGCGATGACGG	FLII	ENSG00000177731	0.13213606918958293	[346]	[407,269,552,269]	2	hSpCas9	negative selection	9245562
18254082	18254105	17	+	27260156	TOV112D	viability	CGAGGTTGCTCAGACCCTCCAGG	FLII	ENSG00000177731	-0.07069185116140941	[837]	[957,844,581,833]	-1	hSpCas9	negative selection	9245563
18256515	18256538	17	+	27260156	TC71	viability	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	-0.3299930223118066	[243]	[253,270,138,166]	-7	hSpCas9	negative selection	9302547
18256554	18256577	17	-	27260156	TC71	viability	AACAACCTGACCACGCTTCATGG	FLII	ENSG00000177731	0.4530685071609626	[1118]	[1632,1403,1636,1910]	9	hSpCas9	negative selection	9302548
18253390	18253413	17	+	27260156	TC71	viability	CCCGTCAAAGTCCAGCTTGTTGG	FLII	ENSG00000177731	0.22774430697403605	[549]	[550,599,698,928]	5	hSpCas9	negative selection	9302549
18253318	18253341	17	+	27260156	TC71	viability	GACCAGCTCCAGGTTGTTGTTGG	FLII	ENSG00000177731	-0.13777816177875735	[322]	[290,351,338,273]	-4	hSpCas9	negative selection	9366812
18254163	18254186	17	-	27260156	TC71	viability	CAGGCAGCTCCCAGCGATGACGG	FLII	ENSG00000177731	-0.45954683983907013	[346]	[236,233,273,341]	-8	hSpCas9	negative selection	9366813
18254082	18254105	17	+	27260156	TC71	viability	CGAGGTTGCTCAGACCCTCCAGG	FLII	ENSG00000177731	-0.2039829151944924	[837]	[569,920,787,848]	-5	hSpCas9	negative selection	9366814
18256515	18256538	17	+	27260156	TC32	viability	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	-0.13463444398443647	[243]	[236,133,294,195]	-2	hSpCas9	negative selection	9423798
18256554	18256577	17	-	27260156	TC32	viability	AACAACCTGACCACGCTTCATGG	FLII	ENSG00000177731	0.746698088868017	[1118]	[1610,1368,2297,1945]	9	hSpCas9	negative selection	9423799
18253390	18253413	17	+	27260156	TC32	viability	CCCGTCAAAGTCCAGCTTGTTGG	FLII	ENSG00000177731	0.04100088864037851	[549]	[523,360,698,610]	0	hSpCas9	negative selection	9423800
18253318	18253341	17	+	27260156	TC32	viability	GACCAGCTCCAGGTTGTTGTTGG	FLII	ENSG00000177731	0.05124274434348364	[322]	[231,285,411,348]	0	hSpCas9	negative selection	9488063
18254163	18254186	17	-	27260156	TC32	viability	CAGGCAGCTCCCAGCGATGACGG	FLII	ENSG00000177731	-0.4145896969109058	[346]	[280,158,241,312]	-6	hSpCas9	negative selection	9488064
18254082	18254105	17	+	27260156	TC32	viability	CGAGGTTGCTCAGACCCTCCAGG	FLII	ENSG00000177731	0.029074330972191698	[837]	[645,517,913,1264]	0	hSpCas9	negative selection	9488065
18254606	18254629	17	-	27869803	HPAFII	viability after 27 days	GGACCTCAGCGAGAACCGCCTGG	FLII	ENSG00000177731	-1.0327494001942756	[74]	[3,31,NaN]	-6	hSpCas9	negative selection	9559427
18254819	18254842	17	-	27869803	HPAFII	viability after 27 days	ACCAGCTGACAGAGTGCCCGCGG	FLII	ENSG00000177731	-5.436854650325847	[381]	[8,0,NaN]	-9	hSpCas9	negative selection	9559428
18255240	18255263	17	+	27869803	HPAFII	viability after 27 days	ACTGTTGGCTCGGGCCACGATGG	FLII	ENSG00000177731	-2.62066043121945	[267]	[29,16,NaN]	-8	hSpCas9	negative selection	9559429
18256515	18256538	17	+	27869803	HPAFII	viability after 27 days	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	-2.047415539494402	[415]	[89,21,NaN]	-8	hSpCas9	negative selection	9559430
18256959	18256982	17	+	27869803	HPAFII	viability after 27 days	GGTTCAGCTTCAGCCACCGCAGG	FLII	ENSG00000177731	-6.0396458044602905	[181]	[1,0,NaN]	-9	hSpCas9	negative selection	9559431
18258647	18258670	17	+	27869803	HPAFII	viability after 27 days	AGGTCCACGCCACGCACGAACGG	FLII	ENSG00000177731	-2.433411347231952	[438]	[27,54,NaN]	-8	hSpCas9	negative selection	9559432
18254606	18254629	17	-	27869803	HPAFII	viability after 15 days	GGACCTCAGCGAGAACCGCCTGG	FLII	ENSG00000177731	-1.8471840920551619	[74]	[51,3,NaN]	-9	hSpCas9	negative selection	9641876
18254819	18254842	17	-	27869803	HPAFII	viability after 15 days	ACCAGCTGACAGAGTGCCCGCGG	FLII	ENSG00000177731	-2.4142524840165183	[381]	[105,58,NaN]	-9	hSpCas9	negative selection	9641877
18255240	18255263	17	+	27869803	HPAFII	viability after 15 days	ACTGTTGGCTCGGGCCACGATGG	FLII	ENSG00000177731	-1.0632762914916356	[267]	[143,133,NaN]	-8	hSpCas9	negative selection	9641878
18256515	18256538	17	+	27869803	HPAFII	viability after 15 days	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	-0.8969181621091968	[415]	[421,126,NaN]	-7	hSpCas9	negative selection	9641879
18256959	18256982	17	+	27869803	HPAFII	viability after 15 days	GGTTCAGCTTCAGCCACCGCAGG	FLII	ENSG00000177731	-4.507313714071019	[181]	[15,3,NaN]	-9	hSpCas9	negative selection	9641880
18258647	18258670	17	+	27869803	HPAFII	viability after 15 days	AGGTCCACGCCACGCACGAACGG	FLII	ENSG00000177731	-1.5199217112680667	[438]	[211,134,NaN]	-8	hSpCas9	negative selection	9641881
18254606	18254629	17	-	27869803	ASPC1	viability after 36 days	GGACCTCAGCGAGAACCGCCTGG	FLII	ENSG00000177731	-2.644010384150903	[208]	[5,0,23]	-9	hSpCas9	negative selection	9724325
18254819	18254842	17	-	27869803	ASPC1	viability after 36 days	ACCAGCTGACAGAGTGCCCGCGG	FLII	ENSG00000177731	-1.6812836218664442	[952]	[227,97,19]	-9	hSpCas9	negative selection	9724326
18255240	18255263	17	+	27869803	ASPC1	viability after 36 days	ACTGTTGGCTCGGGCCACGATGG	FLII	ENSG00000177731	-1.390178630585893	[586]	[155,29,60]	-8	hSpCas9	negative selection	9724327
18256515	18256538	17	+	27869803	ASPC1	viability after 36 days	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	-0.7944483988703903	[878]	[27,266,207]	-7	hSpCas9	negative selection	9724328
18256959	18256982	17	+	27869803	ASPC1	viability after 36 days	GGTTCAGCTTCAGCCACCGCAGG	FLII	ENSG00000177731	-1.4073257340696097	[450]	[18,71,76]	-8	hSpCas9	negative selection	9724329
18258647	18258670	17	+	27869803	ASPC1	viability after 36 days	AGGTCCACGCCACGCACGAACGG	FLII	ENSG00000177731	-1.4730314460198706	[963]	[87,84,171]	-8	hSpCas9	negative selection	9724330
18254606	18254629	17	-	27869803	PATU8988S	viability after 35 days	GGACCTCAGCGAGAACCGCCTGG	FLII	ENSG00000177731	-0.4103951419759244	[151]	[72,18,NaN]	-4	hSpCas9	negative selection	9806774
18254819	18254842	17	-	27869803	PATU8988S	viability after 35 days	ACCAGCTGACAGAGTGCCCGCGG	FLII	ENSG00000177731	-2.2555739535395096	[657]	[53,56,NaN]	-9	hSpCas9	negative selection	9806775
18255240	18255263	17	+	27869803	PATU8988S	viability after 35 days	ACTGTTGGCTCGGGCCACGATGG	FLII	ENSG00000177731	-1.0715135132519855	[552]	[94,116,NaN]	-7	hSpCas9	negative selection	9806776
18256515	18256538	17	+	27869803	PATU8988S	viability after 35 days	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	0.4582115577587663	[806]	[237,655,NaN]	5	hSpCas9	negative selection	9806777
18256959	18256982	17	+	27869803	PATU8988S	viability after 35 days	GGTTCAGCTTCAGCCACCGCAGG	FLII	ENSG00000177731	-1.424944391478708	[456]	[89,46,NaN]	-8	hSpCas9	negative selection	9806778
18258647	18258670	17	+	27869803	PATU8988S	viability after 35 days	AGGTCCACGCCACGCACGAACGG	FLII	ENSG00000177731	-1.3660900963888474	[786]	[106,138,NaN]	-8	hSpCas9	negative selection	9806779
18254606	18254629	17	-	27869803	PATU8988S	viability after 31 days	GGACCTCAGCGAGAACCGCCTGG	FLII	ENSG00000177731	0.24459741090443798	[151]	[106,26,NaN]	3	hSpCas9	negative selection	9889223
18254819	18254842	17	-	27869803	PATU8988S	viability after 31 days	ACCAGCTGACAGAGTGCCCGCGG	FLII	ENSG00000177731	-2.048157779041775	[657]	[62,63,NaN]	-9	hSpCas9	negative selection	9889224
18255240	18255263	17	+	27869803	PATU8988S	viability after 31 days	ACTGTTGGCTCGGGCCACGATGG	FLII	ENSG00000177731	-0.6044210059745293	[552]	[115,181,NaN]	-6	hSpCas9	negative selection	9889225
18256515	18256538	17	+	27869803	PATU8988S	viability after 31 days	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	0.6387678881464333	[806]	[211,868,NaN]	7	hSpCas9	negative selection	9889226
18256959	18256982	17	+	27869803	PATU8988S	viability after 31 days	GGTTCAGCTTCAGCCACCGCAGG	FLII	ENSG00000177731	-1.095312606583682	[456]	[123,35,NaN]	-8	hSpCas9	negative selection	9889227
18258647	18258670	17	+	27869803	PATU8988S	viability after 31 days	AGGTCCACGCCACGCACGAACGG	FLII	ENSG00000177731	-1.0801496577269567	[786]	[81,232,NaN]	-8	hSpCas9	negative selection	9889228
18254606	18254629	17	-	27869803	HPAFII	viability after 35 days	GGACCTCAGCGAGAACCGCCTGG	FLII	ENSG00000177731	-5.246730137499206	[74]	[0,0,NaN]	-9	hSpCas9	negative selection	9971672
18254819	18254842	17	-	27869803	HPAFII	viability after 35 days	ACCAGCTGACAGAGTGCCCGCGG	FLII	ENSG00000177731	-4.716471509674233	[381]	[12,0,NaN]	-9	hSpCas9	negative selection	9971673
18255240	18255263	17	+	27869803	HPAFII	viability after 35 days	ACTGTTGGCTCGGGCCACGATGG	FLII	ENSG00000177731	-3.2946796382337546	[267]	[18,7,NaN]	-8	hSpCas9	negative selection	9971674
18256515	18256538	17	+	27869803	HPAFII	viability after 35 days	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	-1.3696579950917398	[415]	[136,18,NaN]	-6	hSpCas9	negative selection	9971675
18256959	18256982	17	+	27869803	HPAFII	viability after 35 days	GGTTCAGCTTCAGCCACCGCAGG	FLII	ENSG00000177731	-6.525706087202021	[181]	[0,0,NaN]	-9	hSpCas9	negative selection	9971676
18258647	18258670	17	+	27869803	HPAFII	viability after 35 days	AGGTCCACGCCACGCACGAACGG	FLII	ENSG00000177731	-1.6300289864238702	[438]	[28,119,NaN]	-7	hSpCas9	negative selection	9971677
18254606	18254629	17	-	27869803	HPAFII	viability after 31 days	GGACCTCAGCGAGAACCGCCTGG	FLII	ENSG00000177731	-5.395447490820623	[74]	[0,0,NaN]	-9	hSpCas9	negative selection	10054121
18254819	18254842	17	-	27869803	HPAFII	viability after 31 days	ACCAGCTGACAGAGTGCCCGCGG	FLII	ENSG00000177731	-4.784552406588551	[381]	[13,0,NaN]	-9	hSpCas9	negative selection	10054122
18255240	18255263	17	+	27869803	HPAFII	viability after 31 days	ACTGTTGGCTCGGGCCACGATGG	FLII	ENSG00000177731	-1.999783191814402	[267]	[39,34,NaN]	-8	hSpCas9	negative selection	10054123
18256515	18256538	17	+	27869803	HPAFII	viability after 31 days	CCAGCACTCACGCGCAGCGATGG	FLII	ENSG00000177731	-2.852011944162961	[415]	[50,11,NaN]	-8	hSpCas9	negative selection	10054124
18256959	18256982	17	+	27869803	HPAFII	viability after 31 days	GGTTCAGCTTCAGCCACCGCAGG	FLII	ENSG00000177731	-6.674423440523439	[181]	[0,0,NaN]	-9	hSpCas9	negative selection	10054125
18258647	18258670	17	+	27869803	HPAFII	viability after 31 days	AGGTCCACGCCACGCACGAACGG	FLII	ENSG00000177731	-1.9263070190345917	[438]	[4,129,NaN]	-8	hSpCas9	negative selection	10054126
18247291	18247314	17	-	28162770	P31FUJ	viability	GGACTACACACGCAATGCGGAGG	FLII	ENSG00000177731	-0.7275668961639565	[154]	[109]	-5	hSpCas9	negative selection	10157712
18247689	18247712	17	-	28162770	P31FUJ	viability	GCACCGGCCACGCCATGCCACGG	FLII	ENSG00000177731	-0.9455202523339075	[294]	[179]	-6	hSpCas9	negative selection	10157713
18246800	18246823	17	-	28162770	P31FUJ	viability	GGTGCCTGTGGAGTACGAGGAGG	FLII	ENSG00000177731	-0.6935317943860915	[138]	[100]	-5	hSpCas9	negative selection	10157714
18251433	18251456	17	+	28162770	P31FUJ	viability	CCAACGCCGCACCTTCCCGCTGG	FLII	ENSG00000177731	0.06976056560605276	[179]	[221]	0	hSpCas9	negative selection	10157715
18251381	18251404	17	-	28162770	P31FUJ	viability	CTACTCCGAGTTCTTCACGGAGG	FLII	ENSG00000177731	-0.743540120113808	[321]	[225]	-5	hSpCas9	negative selection	10157716
18251285	18251308	17	+	28162770	P31FUJ	viability	CAGCCTCGTAGAACTTGCCGTGG	FLII	ENSG00000177731	0.3968293456405061	[52]	[81]	4	hSpCas9	negative selection	10157717
18250870	18250893	17	-	28162770	P31FUJ	viability	TGAGTGCCGCACTGTCCGGGAGG	FLII	ENSG00000177731	-0.9808229870895806	[130]	[77]	-6	hSpCas9	negative selection	10157718
18249362	18249385	17	-	28162770	P31FUJ	viability	ATTGAGGGTGGAACAGCCAGTGG	FLII	ENSG00000177731	-0.7790323106468202	[440]	[301]	-6	hSpCas9	negative selection	10157719
18248627	18248650	17	-	28162770	P31FUJ	viability	GGAGCTCCCAGAGTTCTGGGAGG	FLII	ENSG00000177731	0.22833170945391923	[76]	[105]	2	hSpCas9	negative selection	10157720
18248617	18248640	17	-	28162770	P31FUJ	viability	GAGTTCTGGGAGGCACTGGGTGG	FLII	ENSG00000177731	-1.0348628268024695	[67]	[38]	-6	hSpCas9	negative selection	10157721
18247291	18247314	17	-	28162770	TF1	viability	GGACTACACACGCAATGCGGAGG	FLII	ENSG00000177731	NaN	[NaN]	[76]	1	hSpCas9	negative selection	10327078
18247689	18247712	17	-	28162770	TF1	viability	GCACCGGCCACGCCATGCCACGG	FLII	ENSG00000177731	NaN	[NaN]	[37]	1	hSpCas9	negative selection	10327079
18246800	18246823	17	-	28162770	TF1	viability	GGTGCCTGTGGAGTACGAGGAGG	FLII	ENSG00000177731	NaN	[NaN]	[18]	1	hSpCas9	negative selection	10327080
18251433	18251456	17	+	28162770	TF1	viability	CCAACGCCGCACCTTCCCGCTGG	FLII	ENSG00000177731	NaN	[NaN]	[127]	1	hSpCas9	negative selection	10327081
18251381	18251404	17	-	28162770	TF1	viability	CTACTCCGAGTTCTTCACGGAGG	FLII	ENSG00000177731	NaN	[NaN]	[110]	1	hSpCas9	negative selection	10327082
18251285	18251308	17	+	28162770	TF1	viability	CAGCCTCGTAGAACTTGCCGTGG	FLII	ENSG00000177731	NaN	[NaN]	[13]	1	hSpCas9	negative selection	10327083
18250870	18250893	17	-	28162770	TF1	viability	TGAGTGCCGCACTGTCCGGGAGG	FLII	ENSG00000177731	NaN	[NaN]	[54]	1	hSpCas9	negative selection	10327084
18249362	18249385	17	-	28162770	TF1	viability	ATTGAGGGTGGAACAGCCAGTGG	FLII	ENSG00000177731	NaN	[NaN]	[325]	1	hSpCas9	negative selection	10327085
18248627	18248650	17	-	28162770	TF1	viability	GGAGCTCCCAGAGTTCTGGGAGG	FLII	ENSG00000177731	NaN	[NaN]	[137]	1	hSpCas9	negative selection	10327086
18248617	18248640	17	-	28162770	TF1	viability	GAGTTCTGGGAGGCACTGGGTGG	FLII	ENSG00000177731	NaN	[NaN]	[19]	1	hSpCas9	negative selection	10327087
18247291	18247314	17	-	28162770	SKM1	viability	GGACTACACACGCAATGCGGAGG	FLII	ENSG00000177731	-0.5444677224930967	[65]	[79]	-4	hSpCas9	negative selection	10496444
18247689	18247712	17	-	28162770	SKM1	viability	GCACCGGCCACGCCATGCCACGG	FLII	ENSG00000177731	-1.496231536840249	[74]	[46]	-7	hSpCas9	negative selection	10496445
18246800	18246823	17	-	28162770	SKM1	viability	GGTGCCTGTGGAGTACGAGGAGG	FLII	ENSG00000177731	-0.9740047914670555	[39]	[35]	-6	hSpCas9	negative selection	10496446
18251433	18251456	17	+	28162770	SKM1	viability	CCAACGCCGCACCTTCCCGCTGG	FLII	ENSG00000177731	-0.48215169513738065	[63]	[80]	-4	hSpCas9	negative selection	10496447
18251381	18251404	17	-	28162770	SKM1	viability	CTACTCCGAGTTCTTCACGGAGG	FLII	ENSG00000177731	-1.0146467759644013	[119]	[104]	-6	hSpCas9	negative selection	10496448
18251285	18251308	17	+	28162770	SKM1	viability	CAGCCTCGTAGAACTTGCCGTGG	FLII	ENSG00000177731	-0.06016143521677009	[22]	[38]	0	hSpCas9	negative selection	10496449
18250870	18250893	17	-	28162770	SKM1	viability	TGAGTGCCGCACTGTCCGGGAGG	FLII	ENSG00000177731	-2.2241001415933512	[36]	[13]	-8	hSpCas9	negative selection	10496450
18249362	18249385	17	-	28162770	SKM1	viability	ATTGAGGGTGGAACAGCCAGTGG	FLII	ENSG00000177731	-0.31950135749282227	[95]	[135]	-3	hSpCas9	negative selection	10496451
18248627	18248650	17	-	28162770	SKM1	viability	GGAGCTCCCAGAGTTCTGGGAGG	FLII	ENSG00000177731	-0.9422959317397175	[24]	[22]	-6	hSpCas9	negative selection	10496452
18248617	18248640	17	-	28162770	SKM1	viability	GAGTTCTGGGAGGCACTGGGTGG	FLII	ENSG00000177731	-0.37454272105078434	[10]	[14]	-3	hSpCas9	negative selection	10496453
18247291	18247314	17	-	28162770	SKM1	viability	GGACTACACACGCAATGCGGAGG	FLII	ENSG00000177731	-0.5444677224930967	[65]	[79]	-4	hSpCas9	negative selection	10665810
18247689	18247712	17	-	28162770	SKM1	viability	GCACCGGCCACGCCATGCCACGG	FLII	ENSG00000177731	-1.496231536840249	[74]	[46]	-7	hSpCas9	negative selection	10665811
18246800	18246823	17	-	28162770	SKM1	viability	GGTGCCTGTGGAGTACGAGGAGG	FLII	ENSG00000177731	-0.9740047914670555	[39]	[35]	-6	hSpCas9	negative selection	10665812
18251433	18251456	17	+	28162770	SKM1	viability	CCAACGCCGCACCTTCCCGCTGG	FLII	ENSG00000177731	-0.48215169513738065	[63]	[80]	-4	hSpCas9	negative selection	10665813
18251381	18251404	17	-	28162770	SKM1	viability	CTACTCCGAGTTCTTCACGGAGG	FLII	ENSG00000177731	-1.0146467759644013	[119]	[104]	-6	hSpCas9	negative selection	10665814
18251285	18251308	17	+	28162770	SKM1	viability	CAGCCTCGTAGAACTTGCCGTGG	FLII	ENSG00000177731	-0.06016143521677009	[22]	[38]	0	hSpCas9	negative selection	10665815
18250870	18250893	17	-	28162770	SKM1	viability	TGAGTGCCGCACTGTCCGGGAGG	FLII	ENSG00000177731	-2.2241001415933512	[36]	[13]	-8	hSpCas9	negative selection	10665816
18249362	18249385	17	-	28162770	SKM1	viability	ATTGAGGGTGGAACAGCCAGTGG	FLII	ENSG00000177731	-0.31950135749282227	[95]	[135]	-3	hSpCas9	negative selection	10665817
18248627	18248650	17	-	28162770	SKM1	viability	GGAGCTCCCAGAGTTCTGGGAGG	FLII	ENSG00000177731	-0.9422959317397175	[24]	[22]	-6	hSpCas9	negative selection	10665818
18248617	18248640	17	-	28162770	SKM1	viability	GAGTTCTGGGAGGCACTGGGTGG	FLII	ENSG00000177731	-0.37454272105078434	[10]	[14]	-3	hSpCas9	negative selection	10665819
18247291	18247314	17	-	28162770	PL21	viability	GGACTACACACGCAATGCGGAGG	FLII	ENSG00000177731	0.4834940047027097	[234]	[142]	4	hSpCas9	negative selection	10835176
18247689	18247712	17	-	28162770	PL21	viability	GCACCGGCCACGCCATGCCACGG	FLII	ENSG00000177731	-0.3643587836721206	[209]	[70]	-3	hSpCas9	negative selection	10835177
18246800	18246823	17	-	28162770	PL21	viability	GGTGCCTGTGGAGTACGAGGAGG	FLII	ENSG00000177731	-0.7417574309471117	[145]	[37]	-5	hSpCas9	negative selection	10835178
18251433	18251456	17	+	28162770	PL21	viability	CCAACGCCGCACCTTCCCGCTGG	FLII	ENSG00000177731	-0.13427942458123907	[231]	[91]	-1	hSpCas9	negative selection	10835179
18251381	18251404	17	-	28162770	PL21	viability	CTACTCCGAGTTCTTCACGGAGG	FLII	ENSG00000177731	-0.2825548348927863	[421]	[150]	-2	hSpCas9	negative selection	10835180
18251285	18251308	17	+	28162770	PL21	viability	CAGCCTCGTAGAACTTGCCGTGG	FLII	ENSG00000177731	-0.4519370820903732	[87]	[27]	-3	hSpCas9	negative selection	10835181
18250870	18250893	17	-	28162770	PL21	viability	TGAGTGCCGCACTGTCCGGGAGG	FLII	ENSG00000177731	0.25260703438345555	[107]	[55]	2	hSpCas9	negative selection	10835182
18249362	18249385	17	-	28162770	PL21	viability	ATTGAGGGTGGAACAGCCAGTGG	FLII	ENSG00000177731	-0.947347997833237	[318]	[71]	-6	hSpCas9	negative selection	10835183
18248627	18248650	17	-	28162770	PL21	viability	GGAGCTCCCAGAGTTCTGGGAGG	FLII	ENSG00000177731	0.5572961976876643	[88]	[56]	5	hSpCas9	negative selection	10835184
18248617	18248640	17	-	28162770	PL21	viability	GAGTTCTGGGAGGCACTGGGTGG	FLII	ENSG00000177731	-0.6072153075682838	[76]	[21]	-4	hSpCas9	negative selection	10835185
18247291	18247314	17	-	28162770	P31FUJ	viability	GGACTACACACGCAATGCGGAGG	FLII	ENSG00000177731	-0.7275668961639565	[154]	[109]	-5	hSpCas9	negative selection	11004542
18247689	18247712	17	-	28162770	P31FUJ	viability	GCACCGGCCACGCCATGCCACGG	FLII	ENSG00000177731	-0.9455202523339075	[294]	[179]	-6	hSpCas9	negative selection	11004543
18246800	18246823	17	-	28162770	P31FUJ	viability	GGTGCCTGTGGAGTACGAGGAGG	FLII	ENSG00000177731	-0.6935317943860915	[138]	[100]	-5	hSpCas9	negative selection	11004544
18251433	18251456	17	+	28162770	P31FUJ	viability	CCAACGCCGCACCTTCCCGCTGG	FLII	ENSG00000177731	0.06976056560605276	[179]	[221]	0	hSpCas9	negative selection	11004545
18251381	18251404	17	-	28162770	P31FUJ	viability	CTACTCCGAGTTCTTCACGGAGG	FLII	ENSG00000177731	-0.743540120113808	[321]	[225]	-5	hSpCas9	negative selection	11004546
18251285	18251308	17	+	28162770	P31FUJ	viability	CAGCCTCGTAGAACTTGCCGTGG	FLII	ENSG00000177731	0.3968293456405061	[52]	[81]	4	hSpCas9	negative selection	11004547
18250870	18250893	17	-	28162770	P31FUJ	viability	TGAGTGCCGCACTGTCCGGGAGG	FLII	ENSG00000177731	-0.9808229870895806	[130]	[77]	-6	hSpCas9	negative selection	11004548
18249362	18249385	17	-	28162770	P31FUJ	viability	ATTGAGGGTGGAACAGCCAGTGG	FLII	ENSG00000177731	-0.7790323106468202	[440]	[301]	-6	hSpCas9	negative selection	11004549
18248627	18248650	17	-	28162770	P31FUJ	viability	GGAGCTCCCAGAGTTCTGGGAGG	FLII	ENSG00000177731	0.22833170945391923	[76]	[105]	2	hSpCas9	negative selection	11004550
18248617	18248640	17	-	28162770	P31FUJ	viability	GAGTTCTGGGAGGCACTGGGTGG	FLII	ENSG00000177731	-1.0348628268024695	[67]	[38]	-6	hSpCas9	negative selection	11004551
18247291	18247314	17	-	28162770	OCIAML5	viability	GGACTACACACGCAATGCGGAGG	FLII	ENSG00000177731	-0.8688422836148237	[172]	[170]	-5	hSpCas9	negative selection	11173908
18247689	18247712	17	-	28162770	OCIAML5	viability	GCACCGGCCACGCCATGCCACGG	FLII	ENSG00000177731	-0.5136503531880657	[173]	[219]	-4	hSpCas9	negative selection	11173909
18246800	18246823	17	-	28162770	OCIAML5	viability	GGTGCCTGTGGAGTACGAGGAGG	FLII	ENSG00000177731	-1.4171295141474483	[107]	[72]	-7	hSpCas9	negative selection	11173910
18251433	18251456	17	+	28162770	OCIAML5	viability	CCAACGCCGCACCTTCCCGCTGG	FLII	ENSG00000177731	-1.2296293647241778	[151]	[116]	-6	hSpCas9	negative selection	11173911
18251381	18251404	17	-	28162770	OCIAML5	viability	CTACTCCGAGTTCTTCACGGAGG	FLII	ENSG00000177731	0.07013127753237003	[199]	[378]	0	hSpCas9	negative selection	11173912
18251285	18251308	17	+	28162770	OCIAML5	viability	CAGCCTCGTAGAACTTGCCGTGG	FLII	ENSG00000177731	-0.2671040701428409	[49]	[74]	-2	hSpCas9	negative selection	11173913
18250870	18250893	17	-	28162770	OCIAML5	viability	TGAGTGCCGCACTGTCCGGGAGG	FLII	ENSG00000177731	0.16839753169571858	[69]	[141]	1	hSpCas9	negative selection	11173914
18249362	18249385	17	-	28162770	OCIAML5	viability	ATTGAGGGTGGAACAGCCAGTGG	FLII	ENSG00000177731	-0.02311211220022441	[160]	[285]	0	hSpCas9	negative selection	11173915
18248627	18248650	17	-	28162770	OCIAML5	viability	GGAGCTCCCAGAGTTCTGGGAGG	FLII	ENSG00000177731	-0.021991572306309326	[80]	[143]	0	hSpCas9	negative selection	11173916
18248617	18248640	17	-	28162770	OCIAML5	viability	GAGTTCTGGGAGGCACTGGGTGG	FLII	ENSG00000177731	-1.3545669113931804	[33]	[23]	-7	hSpCas9	negative selection	11173917
18247291	18247314	17	-	28162770	EOL1	viability	GGACTACACACGCAATGCGGAGG	FLII	ENSG00000177731	0.013815109667621839	[375]	[199]	0	hSpCas9	negative selection	11343274
18247689	18247712	17	-	28162770	EOL1	viability	GCACCGGCCACGCCATGCCACGG	FLII	ENSG00000177731	0.4099745987407763	[309]	[216]	4	hSpCas9	negative selection	11343275
18246800	18246823	17	-	28162770	EOL1	viability	GGTGCCTGTGGAGTACGAGGAGG	FLII	ENSG00000177731	-0.5582343343441434	[217]	[77]	-4	hSpCas9	negative selection	11343276
18251433	18251456	17	+	28162770	EOL1	viability	CCAACGCCGCACCTTCCCGCTGG	FLII	ENSG00000177731	0.48585900422704553	[327]	[241]	4	hSpCas9	negative selection	11343277
18251381	18251404	17	-	28162770	EOL1	viability	CTACTCCGAGTTCTTCACGGAGG	FLII	ENSG00000177731	-0.5114155665628576	[624]	[230]	-4	hSpCas9	negative selection	11343278
18251285	18251308	17	+	28162770	EOL1	viability	CAGCCTCGTAGAACTTGCCGTGG	FLII	ENSG00000177731	-2.616020609792168	[127]	[10]	-9	hSpCas9	negative selection	11343279
18250870	18250893	17	-	28162770	EOL1	viability	TGAGTGCCGCACTGTCCGGGAGG	FLII	ENSG00000177731	-0.9499213463456067	[153]	[41]	-6	hSpCas9	negative selection	11343280
18249362	18249385	17	-	28162770	EOL1	viability	ATTGAGGGTGGAACAGCCAGTGG	FLII	ENSG00000177731	0.2752348594393209	[446]	[284]	2	hSpCas9	negative selection	11343281
18248627	18248650	17	-	28162770	EOL1	viability	GGAGCTCCCAGAGTTCTGGGAGG	FLII	ENSG00000177731	-2.245377229871778	[89]	[9]	-8	hSpCas9	negative selection	11343282
18248617	18248640	17	-	28162770	EOL1	viability	GAGTTCTGGGAGGCACTGGGTGG	FLII	ENSG00000177731	0.09447277301284718	[63]	[35]	0	hSpCas9	negative selection	11343283
18247291	18247314	17	-	28162770	MOLM13	viability	GGACTACACACGCAATGCGGAGG	FLII	ENSG00000177731	-0.4122218829483393	[426]	[231]	-2	hSpCas9	negative selection	11512640
18247689	18247712	17	-	28162770	MOLM13	viability	GCACCGGCCACGCCATGCCACGG	FLII	ENSG00000177731	-1.5732798074318255	[390]	[94]	-7	hSpCas9	negative selection	11512641
18246800	18246823	17	-	28162770	MOLM13	viability	GGTGCCTGTGGAGTACGAGGAGG	FLII	ENSG00000177731	-0.2983705194156654	[198]	[116]	-2	hSpCas9	negative selection	11512642
18251433	18251456	17	+	28162770	MOLM13	viability	CCAACGCCGCACCTTCCCGCTGG	FLII	ENSG00000177731	0.1856070911175065	[331]	[272]	1	hSpCas9	negative selection	11512643
18251381	18251404	17	-	28162770	MOLM13	viability	CTACTCCGAGTTCTTCACGGAGG	FLII	ENSG00000177731	0.23742790949913795	[507]	[432]	1	hSpCas9	negative selection	11512644
18251285	18251308	17	+	28162770	MOLM13	viability	CAGCCTCGTAGAACTTGCCGTGG	FLII	ENSG00000177731	-0.7337444796250718	[137]	[59]	-4	hSpCas9	negative selection	11512645
18250870	18250893	17	-	28162770	MOLM13	viability	TGAGTGCCGCACTGTCCGGGAGG	FLII	ENSG00000177731	-1.0030013524677828	[157]	[56]	-5	hSpCas9	negative selection	11512646
18249362	18249385	17	-	28162770	MOLM13	viability	ATTGAGGGTGGAACAGCCAGTGG	FLII	ENSG00000177731	0.27004709953730244	[436]	[380]	2	hSpCas9	negative selection	11512647
18248627	18248650	17	-	28162770	MOLM13	viability	GGAGCTCCCAGAGTTCTGGGAGG	FLII	ENSG00000177731	0.46788938154457893	[110]	[110]	3	hSpCas9	negative selection	11512648
18248617	18248640	17	-	28162770	MOLM13	viability	GAGTTCTGGGAGGCACTGGGTGG	FLII	ENSG00000177731	-0.7858672107012041	[61]	[25]	-4	hSpCas9	negative selection	11512649
18247291	18247314	17	-	28162770	HEL	viability	GGACTACACACGCAATGCGGAGG	FLII	ENSG00000177731	-0.6791892628870054	[274]	[109]	-4	hSpCas9	negative selection	11682006
18247689	18247712	17	-	28162770	HEL	viability	GCACCGGCCACGCCATGCCACGG	FLII	ENSG00000177731	-1.502691607521207	[291]	[65]	-7	hSpCas9	negative selection	11682007
18246800	18246823	17	-	28162770	HEL	viability	GGTGCCTGTGGAGTACGAGGAGG	FLII	ENSG00000177731	-0.8062459992018245	[171]	[62]	-5	hSpCas9	negative selection	11682008
18251433	18251456	17	+	28162770	HEL	viability	CCAACGCCGCACCTTCCCGCTGG	FLII	ENSG00000177731	-0.44591878782003996	[301]	[141]	-3	hSpCas9	negative selection	11682009
18251381	18251404	17	-	28162770	HEL	viability	CTACTCCGAGTTCTTCACGGAGG	FLII	ENSG00000177731	-1.2878397670421635	[567]	[148]	-6	hSpCas9	negative selection	11682010
18251285	18251308	17	+	28162770	HEL	viability	CAGCCTCGTAGAACTTGCCGTGG	FLII	ENSG00000177731	-0.15507231738637617	[112]	[64]	-1	hSpCas9	negative selection	11682011
18250870	18250893	17	-	28162770	HEL	viability	TGAGTGCCGCACTGTCCGGGAGG	FLII	ENSG00000177731	-2.1093336545560577	[127]	[18]	-8	hSpCas9	negative selection	11682012
18249362	18249385	17	-	28162770	HEL	viability	ATTGAGGGTGGAACAGCCAGTGG	FLII	ENSG00000177731	-1.3226809362894985	[370]	[94]	-6	hSpCas9	negative selection	11682013
18248627	18248650	17	-	28162770	HEL	viability	GGAGCTCCCAGAGTTCTGGGAGG	FLII	ENSG00000177731	-1.2239946371361787	[123]	[33]	-6	hSpCas9	negative selection	11682014
18248617	18248640	17	-	28162770	HEL	viability	GAGTTCTGGGAGGCACTGGGTGG	FLII	ENSG00000177731	-1.9422236687207992	[77]	[12]	-8	hSpCas9	negative selection	11682015
18247291	18247314	17	-	28162770	MV411	viability	GGACTACACACGCAATGCGGAGG	FLII	ENSG00000177731	-1.425397705963715	[219]	[68]	-7	hSpCas9	negative selection	11851372
18247689	18247712	17	-	28162770	MV411	viability	GCACCGGCCACGCCATGCCACGG	FLII	ENSG00000177731	-0.5745641472392301	[197]	[111]	-4	hSpCas9	negative selection	11851373
18246800	18246823	17	-	28162770	MV411	viability	GGTGCCTGTGGAGTACGAGGAGG	FLII	ENSG00000177731	-2.5339221627418844	[164]	[23]	-8	hSpCas9	negative selection	11851374
18251433	18251456	17	+	28162770	MV411	viability	CCAACGCCGCACCTTCCCGCTGG	FLII	ENSG00000177731	0.04232312087816298	[248]	[215]	0	hSpCas9	negative selection	11851375
18251381	18251404	17	-	28162770	MV411	viability	CTACTCCGAGTTCTTCACGGAGG	FLII	ENSG00000177731	-1.1347080669386937	[317]	[121]	-6	hSpCas9	negative selection	11851376
18251285	18251308	17	+	28162770	MV411	viability	CAGCCTCGTAGAACTTGCCGTGG	FLII	ENSG00000177731	-0.1874995059337734	[72]	[53]	-1	hSpCas9	negative selection	11851377
18250870	18250893	17	-	28162770	MV411	viability	TGAGTGCCGCACTGTCCGGGAGG	FLII	ENSG00000177731	0.052621373798752424	[94]	[82]	0	hSpCas9	negative selection	11851378
18249362	18249385	17	-	28162770	MV411	viability	ATTGAGGGTGGAACAGCCAGTGG	FLII	ENSG00000177731	-0.5025841962088773	[295]	[175]	-4	hSpCas9	negative selection	11851379
18248627	18248650	17	-	28162770	MV411	viability	GGAGCTCCCAGAGTTCTGGGAGG	FLII	ENSG00000177731	-4.161953385354926	[84]	[3]	-9	hSpCas9	negative selection	11851380
18248617	18248640	17	-	28162770	MV411	viability	GAGTTCTGGGAGGCACTGGGTGG	FLII	ENSG00000177731	-0.2119940678545218	[32]	[23]	-2	hSpCas9	negative selection	11851381
18247291	18247314	17	-	28162770	MONOMAC1	viability	GGACTACACACGCAATGCGGAGG	FLII	ENSG00000177731	-0.5122390787586026	[106]	[85]	-4	hSpCas9	negative selection	12020738
18247689	18247712	17	-	28162770	MONOMAC1	viability	GCACCGGCCACGCCATGCCACGG	FLII	ENSG00000177731	-1.78199934778071	[128]	[42]	-8	hSpCas9	negative selection	12020739
18246800	18246823	17	-	28162770	MONOMAC1	viability	GGTGCCTGTGGAGTACGAGGAGG	FLII	ENSG00000177731	-1.1176023795651486	[105]	[55]	-7	hSpCas9	negative selection	12020740
18251433	18251456	17	+	28162770	MONOMAC1	viability	CCAACGCCGCACCTTCCCGCTGG	FLII	ENSG00000177731	-0.049191379088159765	[138]	[153]	0	hSpCas9	negative selection	12020741
18251381	18251404	17	-	28162770	MONOMAC1	viability	CTACTCCGAGTTCTTCACGGAGG	FLII	ENSG00000177731	-0.47626049099267775	[232]	[191]	-4	hSpCas9	negative selection	12020742
18251285	18251308	17	+	28162770	MONOMAC1	viability	CAGCCTCGTAGAACTTGCCGTGG	FLII	ENSG00000177731	0.24353574432642744	[41]	[56]	2	hSpCas9	negative selection	12020743
18250870	18250893	17	-	28162770	MONOMAC1	viability	TGAGTGCCGCACTGTCCGGGAGG	FLII	ENSG00000177731	-1.5975747766432824	[65]	[24]	-8	hSpCas9	negative selection	12020744
18249362	18249385	17	-	28162770	MONOMAC1	viability	ATTGAGGGTGGAACAGCCAGTGG	FLII	ENSG00000177731	-0.7364024813405993	[217]	[149]	-6	hSpCas9	negative selection	12020745
18248627	18248650	17	-	28162770	MONOMAC1	viability	GGAGCTCCCAGAGTTCTGGGAGG	FLII	ENSG00000177731	-1.9905859695921273	[51]	[14]	-8	hSpCas9	negative selection	12020746
18248617	18248640	17	-	28162770	MONOMAC1	viability	GAGTTCTGGGAGGCACTGGGTGG	FLII	ENSG00000177731	-1.2965725206104683	[29]	[13]	-7	hSpCas9	negative selection	12020747
18247291	18247314	17	-	28162770	OCIAML2	viability	GGACTACACACGCAATGCGGAGG	FLII	ENSG00000177731	-1.1634483157239852	[58]	[145]	-6	hSpCas9	negative selection	12190104
18247689	18247712	17	-	28162770	OCIAML2	viability	GCACCGGCCACGCCATGCCACGG	FLII	ENSG00000177731	-1.4050414836145844	[42]	[89]	-7	hSpCas9	negative selection	12190105
18246800	18246823	17	-	28162770	OCIAML2	viability	GGTGCCTGTGGAGTACGAGGAGG	FLII	ENSG00000177731	-1.337363294378697	[30]	[67]	-7	hSpCas9	negative selection	12190106
18251433	18251456	17	+	28162770	OCIAML2	viability	CCAACGCCGCACCTTCCCGCTGG	FLII	ENSG00000177731	0.20607524410657038	[32]	[210]	2	hSpCas9	negative selection	12190107
18251381	18251404	17	-	28162770	OCIAML2	viability	CTACTCCGAGTTCTTCACGGAGG	FLII	ENSG00000177731	-1.1864213963039574	[61]	[150]	-7	hSpCas9	negative selection	12190108
18251285	18251308	17	+	28162770	OCIAML2	viability	CAGCCTCGTAGAACTTGCCGTGG	FLII	ENSG00000177731	-2.7925579201295236	[19]	[15]	-9	hSpCas9	negative selection	12190109
18250870	18250893	17	-	28162770	OCIAML2	viability	TGAGTGCCGCACTGTCCGGGAGG	FLII	ENSG00000177731	-1.733664231075955	[17]	[29]	-8	hSpCas9	negative selection	12190110
18249362	18249385	17	-	28162770	OCIAML2	viability	ATTGAGGGTGGAACAGCCAGTGG	FLII	ENSG00000177731	-1.6910198936674612	[59]	[102]	-7	hSpCas9	negative selection	12190111
18248627	18248650	17	-	28162770	OCIAML2	viability	GGAGCTCCCAGAGTTCTGGGAGG	FLII	ENSG00000177731	-3.396629243798384	[18]	[9]	-9	hSpCas9	negative selection	12190112
18248617	18248640	17	-	28162770	OCIAML2	viability	GAGTTCTGGGAGGCACTGGGTGG	FLII	ENSG00000177731	-0.20759541940836712	[4]	[23]	-2	hSpCas9	negative selection	12190113
18247291	18247314	17	-	28162770	OCIAML3	viability	GGACTACACACGCAATGCGGAGG	FLII	ENSG00000177731	0.21334728173344103	[55]	[195]	2	hSpCas9	negative selection	12359470
18247689	18247712	17	-	28162770	OCIAML3	viability	GCACCGGCCACGCCATGCCACGG	FLII	ENSG00000177731	-0.04701298980202734	[76]	[224]	0	hSpCas9	negative selection	12359471
18246800	18246823	17	-	28162770	OCIAML3	viability	GGTGCCTGTGGAGTACGAGGAGG	FLII	ENSG00000177731	-1.594007640324163	[36]	[36]	-8	hSpCas9	negative selection	12359472
18251433	18251456	17	+	28162770	OCIAML3	viability	CCAACGCCGCACCTTCCCGCTGG	FLII	ENSG00000177731	0.18359993833938884	[41]	[143]	1	hSpCas9	negative selection	12359473
18251381	18251404	17	-	28162770	OCIAML3	viability	CTACTCCGAGTTCTTCACGGAGG	FLII	ENSG00000177731	-0.8039307096983944	[95]	[165]	-5	hSpCas9	negative selection	12359474
18251285	18251308	17	+	28162770	OCIAML3	viability	CAGCCTCGTAGAACTTGCCGTGG	FLII	ENSG00000177731	1.1846359850919135	[28]	[198]	8	hSpCas9	negative selection	12359475
18250870	18250893	17	-	28162770	OCIAML3	viability	TGAGTGCCGCACTGTCCGGGAGG	FLII	ENSG00000177731	0.036042749925530915	[20]	[64]	0	hSpCas9	negative selection	12359476
18249362	18249385	17	-	28162770	OCIAML3	viability	ATTGAGGGTGGAACAGCCAGTGG	FLII	ENSG00000177731	-0.5423455205016706	[95]	[198]	-4	hSpCas9	negative selection	12359477
18248627	18248650	17	-	28162770	OCIAML3	viability	GGAGCTCCCAGAGTTCTGGGAGG	FLII	ENSG00000177731	-1.3488951424876316	[26]	[31]	-7	hSpCas9	negative selection	12359478
18248617	18248640	17	-	28162770	OCIAML3	viability	GAGTTCTGGGAGGCACTGGGTGG	FLII	ENSG00000177731	-0.22203886293720498	[16]	[43]	-2	hSpCas9	negative selection	12359479