Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 9843
• Symbol: heph
• Description: hephaestin

DataSource: http://genomecrispr.dkfz.de/#!/results/heph

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
66197693	66197716	X	-	26472758	Jiyoye	viability	AGGGCTTGGCAACCAAGCCAGGG	HEPH	ENSG00000089472	0.036337686137564607	[74]	[57]	0	hSpCas9	negative selection	70167
66260108	66260131	X	+	26472758	Jiyoye	viability	GAACTACCGGGCAGATGTGGTGG	HEPH	ENSG00000089472	-1.7303281422440615	[43]	[9]	-8	hSpCas9	negative selection	70168
66189803	66189826	X	+	26472758	Jiyoye	viability	GGACAGATGCTGACTACCCGTGG	HEPH	ENSG00000089472	0.7080418608654062	[137]	[169]	5	hSpCas9	negative selection	70169
66195117	66195140	X	+	26472758	Jiyoye	viability	GGTGGGTGACACCATTCAGGTGG	HEPH	ENSG00000089472	1.0592520780855665	[90]	[142]	7	hSpCas9	negative selection	70170
66197761	66197784	X	-	26472758	Jiyoye	viability	ACAAGCAGGATCCTGAGCAGTGG	HEPH	ENSG00000089472	0.42763948406558894	[209]	[212]	3	hSpCas9	negative selection	70171
66197847	66197870	X	-	26472758	Jiyoye	viability	CCAGCCCTGCACACCAGCAGCGG	HEPH	ENSG00000089472	0.33525045470325	[328]	[312]	2	hSpCas9	negative selection	70172
66198865	66198888	X	+	26472758	Jiyoye	viability	ATTGGGCCTGCAGAAAGGGGTGG	HEPH	ENSG00000089472	0.9274321928392141	[75]	[108]	6	hSpCas9	negative selection	70173
66200580	66200603	X	+	26472758	Jiyoye	viability	CATGTGCAAGGGTGACACAGTGG	HEPH	ENSG00000089472	0.3728238767150964	[84]	[82]	3	hSpCas9	negative selection	70174
66207256	66207279	X	+	26472758	Jiyoye	viability	GTATTCAGGGAATACACTGATGG	HEPH	ENSG00000089472	-0.1759574486582005	[393]	[262]	-1	hSpCas9	negative selection	70175
66208176	66208199	X	-	26472758	Jiyoye	viability	GAGCATGCACAGAGTAGGGGCGG	HEPH	ENSG00000089472	-0.89009065914722	[289]	[117]	-6	hSpCas9	negative selection	70176
66197693	66197716	X	-	26472758	KBM7	viability	AGGGCTTGGCAACCAAGCCAGGG	HEPH	ENSG00000089472	0.6365329294185721	[331,230]	[240,168]	7	hSpCas9	negative selection	261285
66260108	66260131	X	+	26472758	KBM7	viability	GAACTACCGGGCAGATGTGGTGG	HEPH	ENSG00000089472	0.37372944661395513	[102,72]	[72,34]	4	hSpCas9	negative selection	261286
66189803	66189826	X	+	26472758	KBM7	viability	GGACAGATGCTGACTACCCGTGG	HEPH	ENSG00000089472	0.6801300439734411	[502,300]	[323,271]	7	hSpCas9	negative selection	261287
66195117	66195140	X	+	26472758	KBM7	viability	GGTGGGTGACACCATTCAGGTGG	HEPH	ENSG00000089472	0.2156061101204514	[540,491]	[281,281]	2	hSpCas9	negative selection	261288
66197761	66197784	X	-	26472758	KBM7	viability	ACAAGCAGGATCCTGAGCAGTGG	HEPH	ENSG00000089472	0.6070902598023741	[658,504]	[465,365]	6	hSpCas9	negative selection	261289
66197847	66197870	X	-	26472758	KBM7	viability	CCAGCCCTGCACACCAGCAGCGG	HEPH	ENSG00000089472	0.7227466454462846	[969,860]	[812,616]	7	hSpCas9	negative selection	261290
66198865	66198888	X	+	26472758	KBM7	viability	ATTGGGCCTGCAGAAAGGGGTGG	HEPH	ENSG00000089472	0.43447743151760726	[343,251]	[162,208]	5	hSpCas9	negative selection	261291
66200580	66200603	X	+	26472758	KBM7	viability	CATGTGCAAGGGTGACACAGTGG	HEPH	ENSG00000089472	0.4220582338557618	[286,309]	[166,209]	4	hSpCas9	negative selection	261292
66207256	66207279	X	+	26472758	KBM7	viability	GTATTCAGGGAATACACTGATGG	HEPH	ENSG00000089472	0.4972202080681476	[1246,1363]	[1070,698]	5	hSpCas9	negative selection	261293
66208176	66208199	X	-	26472758	KBM7	viability	GAGCATGCACAGAGTAGGGGCGG	HEPH	ENSG00000089472	0.17420014662770777	[565,530]	[244,332]	1	hSpCas9	negative selection	261294
66197693	66197716	X	-	26472758	Raji	viability	AGGGCTTGGCAACCAAGCCAGGG	HEPH	ENSG00000089472	0.6388305267677541	[118]	[42]	6	hSpCas9	negative selection	452403
66260108	66260131	X	+	26472758	Raji	viability	GAACTACCGGGCAGATGTGGTGG	HEPH	ENSG00000089472	0.46352734559887465	[49]	[15]	4	hSpCas9	negative selection	452404
66189803	66189826	X	+	26472758	Raji	viability	GGACAGATGCTGACTACCCGTGG	HEPH	ENSG00000089472	0.6972952520664892	[193]	[72]	6	hSpCas9	negative selection	452405
66195117	66195140	X	+	26472758	Raji	viability	GGTGGGTGACACCATTCAGGTGG	HEPH	ENSG00000089472	1.0647391979651057	[205]	[99]	8	hSpCas9	negative selection	452406
66197761	66197784	X	-	26472758	Raji	viability	ACAAGCAGGATCCTGAGCAGTGG	HEPH	ENSG00000089472	0.8936042443418595	[333]	[143]	7	hSpCas9	negative selection	452407
66197847	66197870	X	-	26472758	Raji	viability	CCAGCCCTGCACACCAGCAGCGG	HEPH	ENSG00000089472	0.5640687320109348	[477]	[163]	5	hSpCas9	negative selection	452408
66198865	66198888	X	+	26472758	Raji	viability	ATTGGGCCTGCAGAAAGGGGTGG	HEPH	ENSG00000089472	-0.6684013076831349	[225]	[32]	-5	hSpCas9	negative selection	452409
66200580	66200603	X	+	26472758	Raji	viability	CATGTGCAAGGGTGACACAGTGG	HEPH	ENSG00000089472	-0.3426493852614483	[152]	[27]	-3	hSpCas9	negative selection	452410
66207256	66207279	X	+	26472758	Raji	viability	GTATTCAGGGAATACACTGATGG	HEPH	ENSG00000089472	0.6194454890473078	[574]	[204]	6	hSpCas9	negative selection	452411
66208176	66208199	X	-	26472758	Raji	viability	GAGCATGCACAGAGTAGGGGCGG	HEPH	ENSG00000089472	-0.4161784206834133	[367]	[63]	-3	hSpCas9	negative selection	452412
66197693	66197716	X	-	26472758	K562	viability	AGGGCTTGGCAACCAAGCCAGGG	HEPH	ENSG00000089472	0.6247890950564705	[178]	[232]	5	hSpCas9	negative selection	643521
66260108	66260131	X	+	26472758	K562	viability	GAACTACCGGGCAGATGTGGTGG	HEPH	ENSG00000089472	-6.31017012401119	[93]	[0]	-9	hSpCas9	negative selection	643522
66189803	66189826	X	+	26472758	K562	viability	GGACAGATGCTGACTACCCGTGG	HEPH	ENSG00000089472	1.1131741943881943	[229]	[419]	8	hSpCas9	negative selection	643523
66195117	66195140	X	+	26472758	K562	viability	GGTGGGTGACACCATTCAGGTGG	HEPH	ENSG00000089472	0.4342938302793992	[390]	[445]	3	hSpCas9	negative selection	643524
66197761	66197784	X	-	26472758	K562	viability	ACAAGCAGGATCCTGAGCAGTGG	HEPH	ENSG00000089472	0.6210552325439955	[532]	[691]	5	hSpCas9	negative selection	643525
66197847	66197870	X	-	26472758	K562	viability	CCAGCCCTGCACACCAGCAGCGG	HEPH	ENSG00000089472	1.0892360366816867	[857]	[1540]	8	hSpCas9	negative selection	643526
66198865	66198888	X	+	26472758	K562	viability	ATTGGGCCTGCAGAAAGGGGTGG	HEPH	ENSG00000089472	-0.20637853472999662	[353]	[258]	-1	hSpCas9	negative selection	643527
66200580	66200603	X	+	26472758	K562	viability	CATGTGCAAGGGTGACACAGTGG	HEPH	ENSG00000089472	0.0015622037702834879	[212]	[179]	0	hSpCas9	negative selection	643528
66207256	66207279	X	+	26472758	K562	viability	GTATTCAGGGAATACACTGATGG	HEPH	ENSG00000089472	0.6795925560079947	[1084]	[1466]	5	hSpCas9	negative selection	643529
66208176	66208199	X	-	26472758	K562	viability	GAGCATGCACAGAGTAGGGGCGG	HEPH	ENSG00000089472	0.4236297796317363	[498]	[564]	3	hSpCas9	negative selection	643530
66170641	66170664	X	-	26627737	DLD1	viability	GCCCAGGTAGTAGACTCGAGTGG	HEPH	ENSG00000089472	-0.08282932359790485	[614]	[96,144,284]	-1	hSpCas9	negative selection	846225
66172568	66172591	X	+	26627737	DLD1	viability	TCATGGTGTCTTCTACGAGAAGG	HEPH	ENSG00000089472	0.6611635863984708	[320]	[168,260,64]	6	hSpCas9	negative selection	846226
66173708	66173731	X	-	26627737	DLD1	viability	TAGATCCAGGTGAGGCACGCTGG	HEPH	ENSG00000089472	0.7734615429624644	[804]	[360,806,177]	7	hSpCas9	negative selection	846227
66188378	66188401	X	-	26627737	DLD1	viability	CTACATCCTGGCGTTGAGGAGGG	HEPH	ENSG00000089472	-0.5223441332848144	[952]	[187,319,130]	-5	hSpCas9	negative selection	846228
66189858	66189881	X	-	26627737	DLD1	viability	CATCTCAGCAGTCACAAAGGTGG	HEPH	ENSG00000089472	0.03777643655049162	[624]	[115,145,318]	0	hSpCas9	negative selection	846229
66192233	66192256	X	+	26627737	DLD1	viability	TCAATGGGACTATGGCCCGATGG	HEPH	ENSG00000089472	0.2365863252470178	[440]	[125,194,166]	2	hSpCas9	negative selection	846230
66170641	66170664	X	-	26627737	GBM cells	viability after 5 days	GCCCAGGTAGTAGACTCGAGTGG	HEPH	ENSG00000089472	-0.23476456034628376	[338]	[190,117]	-4	hSpCas9	negative selection	928540
66172568	66172591	X	+	26627737	GBM cells	viability after 5 days	TCATGGTGTCTTCTACGAGAAGG	HEPH	ENSG00000089472	-0.29648181407274515	[299]	[131,129]	-4	hSpCas9	negative selection	928541
66173708	66173731	X	-	26627737	GBM cells	viability after 5 days	TAGATCCAGGTGAGGCACGCTGG	HEPH	ENSG00000089472	0.6126096897290445	[299]	[273,217]	8	hSpCas9	negative selection	928542
66188378	66188401	X	-	26627737	GBM cells	viability after 5 days	CTACATCCTGGCGTTGAGGAGGG	HEPH	ENSG00000089472	-0.0679953386458918	[430]	[225,214]	-1	hSpCas9	negative selection	928543
66189858	66189881	X	-	26627737	GBM cells	viability after 5 days	CATCTCAGCAGTCACAAAGGTGG	HEPH	ENSG00000089472	0.09939634330396752	[435]	[204,295]	1	hSpCas9	negative selection	928544
66192233	66192256	X	+	26627737	GBM cells	viability after 5 days	TCAATGGGACTATGGCCCGATGG	HEPH	ENSG00000089472	0.9783483423800905	[158]	[176,158]	9	hSpCas9	negative selection	928545
66170641	66170664	X	-	26627737	GBM cells	viability after 13 days	GCCCAGGTAGTAGACTCGAGTGG	HEPH	ENSG00000089472	-0.21952617465270174	[338]	[168,148]	-3	hSpCas9	negative selection	1010855
66172568	66172591	X	+	26627737	GBM cells	viability after 13 days	TCATGGTGTCTTCTACGAGAAGG	HEPH	ENSG00000089472	0.06367342878334503	[299]	[125,205]	0	hSpCas9	negative selection	1010856
66173708	66173731	X	-	26627737	GBM cells	viability after 13 days	TAGATCCAGGTGAGGCACGCTGG	HEPH	ENSG00000089472	0.6249547709256988	[299]	[298,211]	7	hSpCas9	negative selection	1010857
66188378	66188401	X	-	26627737	GBM cells	viability after 13 days	CTACATCCTGGCGTTGAGGAGGG	HEPH	ENSG00000089472	0.09166823961036685	[430]	[214,276]	1	hSpCas9	negative selection	1010858
66189858	66189881	X	-	26627737	GBM cells	viability after 13 days	CATCTCAGCAGTCACAAAGGTGG	HEPH	ENSG00000089472	-0.01191347986999447	[435]	[227,239]	0	hSpCas9	negative selection	1010859
66192233	66192256	X	+	26627737	GBM cells	viability after 13 days	TCAATGGGACTATGGCCCGATGG	HEPH	ENSG00000089472	1.0378442112121107	[158]	[223,138]	9	hSpCas9	negative selection	1010860
66170641	66170664	X	-	26627737	GBM cells	viability after 21 days	GCCCAGGTAGTAGACTCGAGTGG	HEPH	ENSG00000089472	-0.6190866269020926	[338]	[121,117]	-5	hSpCas9	negative selection	1093170
66172568	66172591	X	+	26627737	GBM cells	viability after 21 days	TCATGGTGTCTTCTACGAGAAGG	HEPH	ENSG00000089472	-0.2510214114412876	[299]	[137,135]	-2	hSpCas9	negative selection	1093171
66173708	66173731	X	-	26627737	GBM cells	viability after 21 days	TAGATCCAGGTGAGGCACGCTGG	HEPH	ENSG00000089472	1.0380914556524987	[299]	[388,284]	8	hSpCas9	negative selection	1093172
66188378	66188401	X	-	26627737	GBM cells	viability after 21 days	CTACATCCTGGCGTTGAGGAGGG	HEPH	ENSG00000089472	0.49248331022415137	[430]	[342,316]	5	hSpCas9	negative selection	1093173
66189858	66189881	X	-	26627737	GBM cells	viability after 21 days	CATCTCAGCAGTCACAAAGGTGG	HEPH	ENSG00000089472	0.7982382073738793	[435]	[460,366]	7	hSpCas9	negative selection	1093174
66192233	66192256	X	+	26627737	GBM cells	viability after 21 days	TCAATGGGACTATGGCCCGATGG	HEPH	ENSG00000089472	1.2335546178366283	[158]	[211,194]	9	hSpCas9	negative selection	1093175
66170641	66170664	X	-	26627737	RPE1	viability after 9 days	GCCCAGGTAGTAGACTCGAGTGG	HEPH	ENSG00000089472	0.33763129387530516	[1078]	[332,547]	2	hSpCas9	negative selection	1175485
66172568	66172591	X	+	26627737	RPE1	viability after 9 days	TCATGGTGTCTTCTACGAGAAGG	HEPH	ENSG00000089472	-1.0201446404993761	[1319]	[177,236]	-6	hSpCas9	negative selection	1175486
66173708	66173731	X	-	26627737	RPE1	viability after 9 days	TAGATCCAGGTGAGGCACGCTGG	HEPH	ENSG00000089472	-1.3962139784965197	[1579]	[90,312]	-7	hSpCas9	negative selection	1175487
66188378	66188401	X	-	26627737	RPE1	viability after 9 days	CTACATCCTGGCGTTGAGGAGGG	HEPH	ENSG00000089472	1.750408905148584	[810]	[607,1171]	8	hSpCas9	negative selection	1175488
66189858	66189881	X	-	26627737	RPE1	viability after 9 days	CATCTCAGCAGTCACAAAGGTGG	HEPH	ENSG00000089472	-0.9409589124127976	[1303]	[192,237]	-6	hSpCas9	negative selection	1175489
66192233	66192256	X	+	26627737	RPE1	viability after 9 days	TCAATGGGACTATGGCCCGATGG	HEPH	ENSG00000089472	0.5831406003290944	[476]	[145,323]	4	hSpCas9	negative selection	1175490
66170641	66170664	X	-	26627737	RPE1	viability after 12 days	GCCCAGGTAGTAGACTCGAGTGG	HEPH	ENSG00000089472	-0.23417475402534518	[1078]	[261,229]	-1	hSpCas9	negative selection	1257800
66172568	66172591	X	+	26627737	RPE1	viability after 12 days	TCATGGTGTCTTCTACGAGAAGG	HEPH	ENSG00000089472	-1.0855195457769873	[1319]	[187,144]	-6	hSpCas9	negative selection	1257801
66173708	66173731	X	-	26627737	RPE1	viability after 12 days	TAGATCCAGGTGAGGCACGCTGG	HEPH	ENSG00000089472	-1.0051810280360733	[1579]	[108,319]	-6	hSpCas9	negative selection	1257802
66188378	66188401	X	-	26627737	RPE1	viability after 12 days	CTACATCCTGGCGTTGAGGAGGG	HEPH	ENSG00000089472	1.4191274377737266	[810]	[554,611]	7	hSpCas9	negative selection	1257803
66189858	66189881	X	-	26627737	RPE1	viability after 12 days	CATCTCAGCAGTCACAAAGGTGG	HEPH	ENSG00000089472	0.062069136419361515	[1303]	[390,338]	0	hSpCas9	negative selection	1257804
66192233	66192256	X	+	26627737	RPE1	viability after 12 days	TCAATGGGACTATGGCCCGATGG	HEPH	ENSG00000089472	1.0099724321684933	[476]	[192,326]	6	hSpCas9	negative selection	1257805
66170641	66170664	X	-	26627737	RPE1	viability after 15 days	GCCCAGGTAGTAGACTCGAGTGG	HEPH	ENSG00000089472	0.6716462686171465	[1078]	[587,387]	4	hSpCas9	negative selection	1340115
66172568	66172591	X	+	26627737	RPE1	viability after 15 days	TCATGGTGTCTTCTACGAGAAGG	HEPH	ENSG00000089472	-1.120283527856881	[1319]	[184,158]	-6	hSpCas9	negative selection	1340116
66173708	66173731	X	-	26627737	RPE1	viability after 15 days	TAGATCCAGGTGAGGCACGCTGG	HEPH	ENSG00000089472	-1.0888909111749707	[1579]	[118,297]	-6	hSpCas9	negative selection	1340117
66188378	66188401	X	-	26627737	RPE1	viability after 15 days	CTACATCCTGGCGTTGAGGAGGG	HEPH	ENSG00000089472	1.7217106026701978	[810]	[718,792]	8	hSpCas9	negative selection	1340118
66189858	66189881	X	-	26627737	RPE1	viability after 15 days	CATCTCAGCAGTCACAAAGGTGG	HEPH	ENSG00000089472	-0.09744472952471106	[1303]	[328,359]	0	hSpCas9	negative selection	1340119
66192233	66192256	X	+	26627737	RPE1	viability after 15 days	TCAATGGGACTATGGCCCGATGG	HEPH	ENSG00000089472	1.3480887110188733	[476]	[286,397]	7	hSpCas9	negative selection	1340120
66170641	66170664	X	-	26627737	RPE1	viability after 18 days	GCCCAGGTAGTAGACTCGAGTGG	HEPH	ENSG00000089472	0.3765219740262156	[1078]	[334,423]	2	hSpCas9	negative selection	1422430
66172568	66172591	X	+	26627737	RPE1	viability after 18 days	TCATGGTGTCTTCTACGAGAAGG	HEPH	ENSG00000089472	-0.8550534053828532	[1319]	[267,120]	-5	hSpCas9	negative selection	1422431
66173708	66173731	X	-	26627737	RPE1	viability after 18 days	TAGATCCAGGTGAGGCACGCTGG	HEPH	ENSG00000089472	-0.6416063697264252	[1579]	[165,387]	-4	hSpCas9	negative selection	1422432
66188378	66188401	X	-	26627737	RPE1	viability after 18 days	CTACATCCTGGCGTTGAGGAGGG	HEPH	ENSG00000089472	1.3238053194586161	[810]	[412,691]	7	hSpCas9	negative selection	1422433
66189858	66189881	X	-	26627737	RPE1	viability after 18 days	CATCTCAGCAGTCACAAAGGTGG	HEPH	ENSG00000089472	0.5000081124759742	[1303]	[531,460]	3	hSpCas9	negative selection	1422434
66192233	66192256	X	+	26627737	RPE1	viability after 18 days	TCAATGGGACTATGGCCCGATGG	HEPH	ENSG00000089472	1.517723934979174	[476]	[283,458]	7	hSpCas9	negative selection	1422435
66170641	66170664	X	-	26627737	HeLa	viability after 8 days	GCCCAGGTAGTAGACTCGAGTGG	HEPH	ENSG00000089472	-0.563146463103556	[920]	[567,216,105]	-5	hSpCas9	negative selection	1504745
66172568	66172591	X	+	26627737	HeLa	viability after 8 days	TCATGGTGTCTTCTACGAGAAGG	HEPH	ENSG00000089472	0.6252972108787327	[305]	[456,89,129]	5	hSpCas9	negative selection	1504746
66173708	66173731	X	-	26627737	HeLa	viability after 8 days	TAGATCCAGGTGAGGCACGCTGG	HEPH	ENSG00000089472	0.5646350259673366	[592]	[476,456,241]	5	hSpCas9	negative selection	1504747
66188378	66188401	X	-	26627737	HeLa	viability after 8 days	CTACATCCTGGCGTTGAGGAGGG	HEPH	ENSG00000089472	0.37778936250241546	[553]	[429,260,276]	3	hSpCas9	negative selection	1504748
66189858	66189881	X	-	26627737	HeLa	viability after 8 days	CATCTCAGCAGTCACAAAGGTGG	HEPH	ENSG00000089472	-0.3703323961685796	[784]	[397,260,169]	-4	hSpCas9	negative selection	1504749
66192233	66192256	X	+	26627737	HeLa	viability after 8 days	TCAATGGGACTATGGCCCGATGG	HEPH	ENSG00000089472	-0.5692829961189572	[449]	[205,100,106]	-5	hSpCas9	negative selection	1504750
66170641	66170664	X	-	26627737	HeLa	viability after 12 days	GCCCAGGTAGTAGACTCGAGTGG	HEPH	ENSG00000089472	-0.5917458335901041	[920]	[177,143,444]	-5	hSpCas9	negative selection	1587060
66172568	66172591	X	+	26627737	HeLa	viability after 12 days	TCATGGTGTCTTCTACGAGAAGG	HEPH	ENSG00000089472	0.9647142646975444	[305]	[216,185,342]	7	hSpCas9	negative selection	1587061
66173708	66173731	X	-	26627737	HeLa	viability after 12 days	TAGATCCAGGTGAGGCACGCTGG	HEPH	ENSG00000089472	0.2313168759641343	[592]	[280,342,232]	2	hSpCas9	negative selection	1587062
66188378	66188401	X	-	26627737	HeLa	viability after 12 days	CTACATCCTGGCGTTGAGGAGGG	HEPH	ENSG00000089472	0.17418341123605463	[553]	[180,236,356]	1	hSpCas9	negative selection	1587063
66189858	66189881	X	-	26627737	HeLa	viability after 12 days	CATCTCAGCAGTCACAAAGGTGG	HEPH	ENSG00000089472	-0.3990483025246271	[784]	[296,203,242]	-4	hSpCas9	negative selection	1587064
66192233	66192256	X	+	26627737	HeLa	viability after 12 days	TCAATGGGACTATGGCCCGATGG	HEPH	ENSG00000089472	0.18108267167144435	[449]	[203,194,234]	1	hSpCas9	negative selection	1587065
66170641	66170664	X	-	26627737	HeLa	viability after 15 days	GCCCAGGTAGTAGACTCGAGTGG	HEPH	ENSG00000089472	-0.0691015424226662	[920]	[480,275,309]	0	hSpCas9	negative selection	1669375
66172568	66172591	X	+	26627737	HeLa	viability after 15 days	TCATGGTGTCTTCTACGAGAAGG	HEPH	ENSG00000089472	0.8648930927815107	[305]	[330,160,183]	6	hSpCas9	negative selection	1669376
66173708	66173731	X	-	26627737	HeLa	viability after 15 days	TAGATCCAGGTGAGGCACGCTGG	HEPH	ENSG00000089472	0.17011869273015912	[592]	[219,414,172]	1	hSpCas9	negative selection	1669377
66188378	66188401	X	-	26627737	HeLa	viability after 15 days	CTACATCCTGGCGTTGAGGAGGG	HEPH	ENSG00000089472	-0.9426385015512453	[553]	[67,126,160]	-7	hSpCas9	negative selection	1669378
66189858	66189881	X	-	26627737	HeLa	viability after 15 days	CATCTCAGCAGTCACAAAGGTGG	HEPH	ENSG00000089472	-0.8295995714153195	[784]	[94,199,250]	-6	hSpCas9	negative selection	1669379
66192233	66192256	X	+	26627737	HeLa	viability after 15 days	TCAATGGGACTATGGCCCGATGG	HEPH	ENSG00000089472	-0.006681306018601091	[449]	[221,196,122]	0	hSpCas9	negative selection	1669380
66170641	66170664	X	-	26627737	HeLa	viability after 18 days	GCCCAGGTAGTAGACTCGAGTGG	HEPH	ENSG00000089472	-0.05909964902292186	[920]	[323,232,309]	0	hSpCas9	negative selection	1751690
66172568	66172591	X	+	26627737	HeLa	viability after 18 days	TCATGGTGTCTTCTACGAGAAGG	HEPH	ENSG00000089472	0.9233859523536495	[305]	[234,139,183]	7	hSpCas9	negative selection	1751691
66173708	66173731	X	-	26627737	HeLa	viability after 18 days	TAGATCCAGGTGAGGCACGCTGG	HEPH	ENSG00000089472	0.20006741298908992	[592]	[151,351,172]	1	hSpCas9	negative selection	1751692
66188378	66188401	X	-	26627737	HeLa	viability after 18 days	CTACATCCTGGCGTTGAGGAGGG	HEPH	ENSG00000089472	-0.9123237785430196	[553]	[48,106,160]	-7	hSpCas9	negative selection	1751693
66189858	66189881	X	-	26627737	HeLa	viability after 18 days	CATCTCAGCAGTCACAAAGGTGG	HEPH	ENSG00000089472	-0.8067904131986419	[784]	[64,170,250]	-6	hSpCas9	negative selection	1751694
66192233	66192256	X	+	26627737	HeLa	viability after 18 days	TCAATGGGACTATGGCCCGATGG	HEPH	ENSG00000089472	-0.007705242146382657	[449]	[151,158,122]	0	hSpCas9	negative selection	1751695
66170641	66170664	X	-	26627737	HCT116	viability after 6 days	GCCCAGGTAGTAGACTCGAGTGG	HEPH	ENSG00000089472	1.6516615645539021	[660]	[573,189]	8	hSpCas9	negative selection	1834005
66172568	66172591	X	+	26627737	HCT116	viability after 6 days	TCATGGTGTCTTCTACGAGAAGG	HEPH	ENSG00000089472	0.10032819806763227	[796]	[230,80]	0	hSpCas9	negative selection	1834006
66173708	66173731	X	-	26627737	HCT116	viability after 6 days	TAGATCCAGGTGAGGCACGCTGG	HEPH	ENSG00000089472	1.3664816413273946	[810]	[320,332]	7	hSpCas9	negative selection	1834007
66188378	66188401	X	-	26627737	HCT116	viability after 6 days	CTACATCCTGGCGTTGAGGAGGG	HEPH	ENSG00000089472	-0.304988748421568	[1319]	[205,146]	-2	hSpCas9	negative selection	1834008
66189858	66189881	X	-	26627737	HCT116	viability after 6 days	CATCTCAGCAGTCACAAAGGTGG	HEPH	ENSG00000089472	0.740491670623806	[866]	[306,183]	4	hSpCas9	negative selection	1834009
66192233	66192256	X	+	26627737	HCT116	viability after 6 days	TCAATGGGACTATGGCCCGATGG	HEPH	ENSG00000089472	1.773228751674794	[291]	[27,227]	8	hSpCas9	negative selection	1834010
66170641	66170664	X	-	26627737	HCT116	viability after 8 days	GCCCAGGTAGTAGACTCGAGTGG	HEPH	ENSG00000089472	0.277794299434979	[342]	[337,175,175]	3	hSpCas9	negative selection	1916320
66172568	66172591	X	+	26627737	HCT116	viability after 8 days	TCATGGTGTCTTCTACGAGAAGG	HEPH	ENSG00000089472	1.3307165142024346	[157]	[160,199,293]	9	hSpCas9	negative selection	1916321
66173708	66173731	X	-	26627737	HCT116	viability after 8 days	TAGATCCAGGTGAGGCACGCTGG	HEPH	ENSG00000089472	-0.4514093352774663	[506]	[281,183,148]	-5	hSpCas9	negative selection	1916322
66188378	66188401	X	-	26627737	HCT116	viability after 8 days	CTACATCCTGGCGTTGAGGAGGG	HEPH	ENSG00000089472	0.07192029073462786	[413]	[298,229,191]	0	hSpCas9	negative selection	1916323
66189858	66189881	X	-	26627737	HCT116	viability after 8 days	CATCTCAGCAGTCACAAAGGTGG	HEPH	ENSG00000089472	0.06295369115916905	[433]	[217,291,238]	0	hSpCas9	negative selection	1916324
66192233	66192256	X	+	26627737	HCT116	viability after 8 days	TCAATGGGACTATGGCCCGATGG	HEPH	ENSG00000089472	0.10891914011246184	[223]	[214,69,115]	1	hSpCas9	negative selection	1916325
66170641	66170664	X	-	26627737	HCT116	viability after 9 days	GCCCAGGTAGTAGACTCGAGTGG	HEPH	ENSG00000089472	1.5263444734043548	[660]	[265,699]	8	hSpCas9	negative selection	1998635
66172568	66172591	X	+	26627737	HCT116	viability after 9 days	TCATGGTGTCTTCTACGAGAAGG	HEPH	ENSG00000089472	0.0923005692076097	[796]	[270,191]	0	hSpCas9	negative selection	1998636
66173708	66173731	X	-	26627737	HCT116	viability after 9 days	TAGATCCAGGTGAGGCACGCTGG	HEPH	ENSG00000089472	0.4992017713282057	[810]	[352,268]	3	hSpCas9	negative selection	1998637
66188378	66188401	X	-	26627737	HCT116	viability after 9 days	CTACATCCTGGCGTTGAGGAGGG	HEPH	ENSG00000089472	0.2826831937075507	[1319]	[225,588]	2	hSpCas9	negative selection	1998638
66189858	66189881	X	-	26627737	HCT116	viability after 9 days	CATCTCAGCAGTCACAAAGGTGG	HEPH	ENSG00000089472	-0.7897794518358194	[866]	[191,87]	-5	hSpCas9	negative selection	1998639
66192233	66192256	X	+	26627737	HCT116	viability after 9 days	TCAATGGGACTATGGCCCGATGG	HEPH	ENSG00000089472	0.6739661353023003	[291]	[215,51]	5	hSpCas9	negative selection	1998640
66170641	66170664	X	-	26627737	HCT116	viability after 12 days	GCCCAGGTAGTAGACTCGAGTGG	HEPH	ENSG00000089472	0.2881612845622491	[342]	[209,293,158]	3	hSpCas9	negative selection	2080950
66172568	66172591	X	+	26627737	HCT116	viability after 12 days	TCATGGTGTCTTCTACGAGAAGG	HEPH	ENSG00000089472	1.3970242650355646	[157]	[164,311,185]	9	hSpCas9	negative selection	2080951
66173708	66173731	X	-	26627737	HCT116	viability after 12 days	TAGATCCAGGTGAGGCACGCTGG	HEPH	ENSG00000089472	0.04803359851549449	[506]	[403,188,219]	0	hSpCas9	negative selection	2080952
66188378	66188401	X	-	26627737	HCT116	viability after 12 days	CTACATCCTGGCGTTGAGGAGGG	HEPH	ENSG00000089472	0.4694762208904035	[413]	[325,277,296]	4	hSpCas9	negative selection	2080953
66189858	66189881	X	-	26627737	HCT116	viability after 12 days	CATCTCAGCAGTCACAAAGGTGG	HEPH	ENSG00000089472	-0.2608238681053708	[433]	[210,220,137]	-3	hSpCas9	negative selection	2080954
66192233	66192256	X	+	26627737	HCT116	viability after 12 days	TCAATGGGACTATGGCCCGATGG	HEPH	ENSG00000089472	0.48805200043265473	[223]	[211,156,121]	5	hSpCas9	negative selection	2080955
66170641	66170664	X	-	26627737	HCT116	viability after 15 days	GCCCAGGTAGTAGACTCGAGTGG	HEPH	ENSG00000089472	0.5290722584247932	[342]	[448,239,184]	5	hSpCas9	negative selection	2163265
66172568	66172591	X	+	26627737	HCT116	viability after 15 days	TCATGGTGTCTTCTACGAGAAGG	HEPH	ENSG00000089472	1.1194501866706195	[157]	[184,211,192]	8	hSpCas9	negative selection	2163266
66173708	66173731	X	-	26627737	HCT116	viability after 15 days	TAGATCCAGGTGAGGCACGCTGG	HEPH	ENSG00000089472	0.17336023672315204	[506]	[355,353,278]	1	hSpCas9	negative selection	2163267
66188378	66188401	X	-	26627737	HCT116	viability after 15 days	CTACATCCTGGCGTTGAGGAGGG	HEPH	ENSG00000089472	0.5658307805204086	[413]	[422,333,307]	5	hSpCas9	negative selection	2163268
66189858	66189881	X	-	26627737	HCT116	viability after 15 days	CATCTCAGCAGTCACAAAGGTGG	HEPH	ENSG00000089472	0.0901237455622621	[433]	[387,168,253]	0	hSpCas9	negative selection	2163269
66192233	66192256	X	+	26627737	HCT116	viability after 15 days	TCAATGGGACTATGGCCCGATGG	HEPH	ENSG00000089472	-0.08652378345054001	[223]	[140,113,110]	-1	hSpCas9	negative selection	2163270
66170641	66170664	X	-	26627737	HCT116	viability after 18 days	GCCCAGGTAGTAGACTCGAGTGG	HEPH	ENSG00000089472	0.6595789721059788	[342]	[493,147,145]	5	hSpCas9	negative selection	2245580
66172568	66172591	X	+	26627737	HCT116	viability after 18 days	TCATGGTGTCTTCTACGAGAAGG	HEPH	ENSG00000089472	0.9822742542946553	[157]	[173,138,139]	7	hSpCas9	negative selection	2245581
66173708	66173731	X	-	26627737	HCT116	viability after 18 days	TAGATCCAGGTGAGGCACGCTGG	HEPH	ENSG00000089472	0.4074252900691513	[506]	[447,336,182]	3	hSpCas9	negative selection	2245582
66188378	66188401	X	-	26627737	HCT116	viability after 18 days	CTACATCCTGGCGTTGAGGAGGG	HEPH	ENSG00000089472	0.06567727186749889	[413]	[172,227,226]	0	hSpCas9	negative selection	2245583
66189858	66189881	X	-	26627737	HCT116	viability after 18 days	CATCTCAGCAGTCACAAAGGTGG	HEPH	ENSG00000089472	0.29372146266912014	[433]	[273,280,212]	2	hSpCas9	negative selection	2245584
66192233	66192256	X	+	26627737	HCT116	viability after 18 days	TCAATGGGACTATGGCCCGATGG	HEPH	ENSG00000089472	0.05322773806439213	[223]	[142,91,102]	0	hSpCas9	negative selection	2245585
66164088	66164111	X	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCTAATTGGTCTTTGCTGAGAGG	HEPH	ENSG00000089472	-1.0452489591217162	[340,314]	[38,29]	-6	dCas9-VP64	positive selection	2444935
66164053	66164076	X	-	25494202	A375	resistance to PLX-4720 (puromycin)	GTGTGGCCAGCCAAAGCTCATGG	HEPH	ENSG00000089472	0.6763998769654637	[124,126]	[24,63]	3	dCas9-VP64	positive selection	2444936
66164115	66164138	X	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGGGTTGTACTTCTGTTATCAGG	HEPH	ENSG00000089472	2.17314886645625	[114,171]	[167,116]	7	dCas9-VP64	positive selection	2444937
66164088	66164111	X	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCTAATTGGTCTTTGCTGAGAGG	HEPH	ENSG00000089472	1.3568638229410288	[153,271]	[115,234]	7	dCas9-VP64	positive selection	2540190
66164053	66164076	X	-	25494202	A375	resistance to PLX-4720 (zeocin)	GTGTGGCCAGCCAAAGCTCATGG	HEPH	ENSG00000089472	0.2913019293130502	[36,129]	[25,38]	2	dCas9-VP64	positive selection	2540191
66164115	66164138	X	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGGGTTGTACTTCTGTTATCAGG	HEPH	ENSG00000089472	-1.0166856991683453	[190,133]	[29,21]	-8	dCas9-VP64	positive selection	2540192
66189884	66189907	X	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AACCAGGTACCAGGTTCCCAGGG	HEPH	ENSG00000089472	-0.0992741871212639	[4,4]	[3,2]	-1	hSpCas9	positive selection	2993044
66199000	66199023	X	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGGGCTTCCAAGACTCCAATCGG	HEPH	ENSG00000089472	-0.14190359540741398	[4,3]	[4,1]	-2	hSpCas9	positive selection	2993045
66200570	66200593	X	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCCAGGCTGGACATGTGCAAGGG	HEPH	ENSG00000089472	-0.1373033491843081	[3,3]	[2,1]	-2	hSpCas9	positive selection	2993046
66189804	66189827	X	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGACAGATGCTGACTACCCGTGG	HEPH	ENSG00000089472	0.26375151136492214	[4,4]	[4,4]	5	hSpCas9	positive selection	2993047
66189884	66189907	X	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AACCAGGTACCAGGTTCCCAGGG	HEPH	ENSG00000089472	-0.5049245630762483	[4,4]	[2,0]	-7	hSpCas9	positive selection	3060902
66199000	66199023	X	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGGGCTTCCAAGACTCCAATCGG	HEPH	ENSG00000089472	0.5328653999557659	[4,4]	[2,5]	8	hSpCas9	positive selection	3060903
66200570	66200593	X	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCCAGGCTGGACATGTGCAAGGG	HEPH	ENSG00000089472	-0.9522401673383135	[3,3]	[1,0]	-9	hSpCas9	positive selection	3060904
66189804	66189827	X	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGACAGATGCTGACTACCCGTGG	HEPH	ENSG00000089472	0.30240214475624455	[4,4]	[4,3]	5	hSpCas9	positive selection	3060905
66189916	66189939		-	24336571	A375	resistance to PLX after 7 days	CTCGAAAGTGACTGTTCACTTGG	HEPH	ENSG00000089472	0.12873461422738966	[16,11]	[15,14]	4	hSpCas9	positive selection	3118791
66189747	66189770		-	24336571	A375	resistance to PLX after 7 days	GCCCATGCCAAACAAGTGCCAGG	HEPH	ENSG00000089472	-0.29661093957003376	[12,10]	[8,9]	-8	hSpCas9	positive selection	3118792
66173747	66173770		+	24336571	A375	resistance to PLX after 7 days	GCTCCACGAGACATTGCAACTGG	HEPH	ENSG00000089472	0.105232045612774	[19,22]	[21,23]	3	hSpCas9	positive selection	3118793
66173790	66173813		-	24336571	A375	resistance to PLX after 7 days	GGGACCTGTACCTCTTTTACAGG	HEPH	ENSG00000089472	0.3111293093940681	[18,17]	[23,21]	8	hSpCas9	positive selection	3118794
66172543	66172566		-	24336571	A375	resistance to PLX after 7 days	GTGGATGGTATAGGGACGAGTGG	HEPH	ENSG00000089472	0.13972690593450332	[19,19]	[20,22]	4	hSpCas9	positive selection	3118795
66172388	66172411		-	24336571	A375	resistance to PLX after 7 days	TCTTGTAGGTTCCCCCTATCCGG	HEPH	ENSG00000089472	0.1728567257965472	[44,57]	[61,52]	5	hSpCas9	positive selection	3118796
66189916	66189939		-	24336571	A375	resistance to PLX after 14 days	CTCGAAAGTGACTGTTCACTTGG	HEPH	ENSG00000089472	0.2946252473349155	[17,12]	[7,8]	3	hSpCas9	positive selection	3176584
66189747	66189770		-	24336571	A375	resistance to PLX after 14 days	GCCCATGCCAAACAAGTGCCAGG	HEPH	ENSG00000089472	-1.047111421314174	[12,11]	[2,1]	-9	hSpCas9	positive selection	3176585
66173747	66173770		+	24336571	A375	resistance to PLX after 14 days	GCTCCACGAGACATTGCAACTGG	HEPH	ENSG00000089472	0.6424800967047044	[18,16]	[11,13]	6	hSpCas9	positive selection	3176586
66173790	66173813		-	24336571	A375	resistance to PLX after 14 days	GGGACCTGTACCTCTTTTACAGG	HEPH	ENSG00000089472	-0.3556451828866337	[23,22]	[8,6]	-4	hSpCas9	positive selection	3176587
66172543	66172566		-	24336571	A375	resistance to PLX after 14 days	GTGGATGGTATAGGGACGAGTGG	HEPH	ENSG00000089472	0.8068299565271804	[25,19]	[15,20]	6	hSpCas9	positive selection	3176588
66172388	66172411		-	24336571	A375	resistance to PLX after 14 days	TCTTGTAGGTTCCCCCTATCCGG	HEPH	ENSG00000089472	0.3080413586351636	[50,51]	[29,28]	3	hSpCas9	positive selection	3176589
66189916	66189939		-	24336571	A375	viability after 7 days	CTCGAAAGTGACTGTTCACTTGG	HEPH	ENSG00000089472	0.5103452054716253	[9]	[16,11]	7	hSpCas9	negative selection	3234377
66189747	66189770		-	24336571	A375	viability after 7 days	GCCCATGCCAAACAAGTGCCAGG	HEPH	ENSG00000089472	0.2588360021222428	[10]	[12,10]	4	hSpCas9	negative selection	3234378
66173747	66173770		+	24336571	A375	viability after 7 days	GCTCCACGAGACATTGCAACTGG	HEPH	ENSG00000089472	-0.08371040931609375	[23]	[19,22]	-1	hSpCas9	negative selection	3234379
66173790	66173813		-	24336571	A375	viability after 7 days	GGGACCTGTACCTCTTTTACAGG	HEPH	ENSG00000089472	0.026255032777750098	[18]	[18,17]	0	hSpCas9	negative selection	3234380
66172543	66172566		-	24336571	A375	viability after 7 days	GTGGATGGTATAGGGACGAGTGG	HEPH	ENSG00000089472	0.13481257745894487	[18]	[19,19]	2	hSpCas9	negative selection	3234381
66172388	66172411		-	24336571	A375	viability after 7 days	TCTTGTAGGTTCCCCCTATCCGG	HEPH	ENSG00000089472	0.4661994799380764	[38]	[44,57]	7	hSpCas9	negative selection	3234382
66189916	66189939		-	24336571	A375	viability after 14 days	CTCGAAAGTGACTGTTCACTTGG	HEPH	ENSG00000089472	0.6806533865186881	[9]	[17,12]	8	hSpCas9	negative selection	3292170
66189747	66189770		-	24336571	A375	viability after 14 days	GCCCATGCCAAACAAGTGCCAGG	HEPH	ENSG00000089472	0.3720215951360326	[10]	[12,11]	5	hSpCas9	negative selection	3292171
66173747	66173770		+	24336571	A375	viability after 14 days	GCTCCACGAGACATTGCAACTGG	HEPH	ENSG00000089472	-0.33294634880919577	[23]	[18,16]	-4	hSpCas9	negative selection	3292172
66173790	66173813		-	24336571	A375	viability after 14 days	GGGACCTGTACCTCTTTTACAGG	HEPH	ENSG00000089472	0.3968447129514953	[18]	[23,22]	5	hSpCas9	negative selection	3292173
66172543	66172566		-	24336571	A375	viability after 14 days	GTGGATGGTATAGGGACGAGTGG	HEPH	ENSG00000089472	0.3699355779570069	[18]	[25,19]	5	hSpCas9	negative selection	3292174
66172388	66172411		-	24336571	A375	viability after 14 days	TCTTGTAGGTTCCCCCTATCCGG	HEPH	ENSG00000089472	0.4939042533989926	[38]	[50,51]	6	hSpCas9	negative selection	3292175
66172388	66172411	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCTTGTAGGTTCCCCCTATCCGG	HEPH	ENSG00000089472	-0.3229631505631524	[172,209]	[0,0]	-2	hSpCas9	positive selection	3353239
66172543	66172566	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	GTGGATGGTATAGGGACGAGTGG	HEPH	ENSG00000089472	2.373564855700971	[32,25]	[0,0]	8	hSpCas9	positive selection	3353240
66173649	66173672	X	+	27383988	293T	resistance to West Nile virus (flavivirus)	GGGGCAGCCATATCTACAACTGG	HEPH	ENSG00000089472	2.4029263183374754	[17,39]	[0,0]	8	hSpCas9	positive selection	3353241
66173747	66173770	X	+	27383988	293T	resistance to West Nile virus (flavivirus)	GCTCCACGAGACATTGCAACTGG	HEPH	ENSG00000089472	0.36250844813789157	[118,118]	[0,0]	2	hSpCas9	positive selection	3372435
66173645	66173668	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTGTAGATATGGCTGCCCCCCGG	HEPH	ENSG00000089472	4.890898656391613	[427,427]	[82,82]	9	hSpCas9	positive selection	3372436
66173721	66173744	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	TACATGAGAATGGTAGATCCAGG	HEPH	ENSG00000089472	-1.181465641132426	[346,346]	[0,0]	-7	hSpCas9	positive selection	3372437
66189884	66189907	X	-	26780180	HT29	viability (Avana library 4 designs)	AACCAGGTACCAGGTTCCCAGGG	HEPH	ENSG00000089472	0.693355820735709	[]	[]	2	hSpCas9	negative selection	3430305
66198999	66199022	X	+	26780180	HT29	viability (Avana library 4 designs)	AGGGCTTCCAAGACTCCAATCGG	HEPH	ENSG00000089472	-0.361510820526898	[]	[]	-5	hSpCas9	negative selection	3430306
66200569	66200592	X	+	26780180	HT29	viability (Avana library 4 designs)	CCCAGGCTGGACATGTGCAAGGG	HEPH	ENSG00000089472	0.810486084316894	[]	[]	3	hSpCas9	negative selection	3430307
66189803	66189826	X	+	26780180	HT29	viability (Avana library 4 designs)	GGACAGATGCTGACTACCCGTGG	HEPH	ENSG00000089472	0.211267100885982	[]	[]	0	hSpCas9	negative selection	3430308
66198999	66199022	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGGGCTTCCAAGACTCCAATCGG	HEPH	ENSG00000089472	1.69517997297438	[]	[]	2	hSpCas9	negative selection	3515400
66189803	66189826	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGACAGATGCTGACTACCCGTGG	HEPH	ENSG00000089472	4.82407072887613	[]	[]	8	hSpCas9	negative selection	3515401
66189884	66189907	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	AACCAGGTACCAGGTTCCCAGGG	HEPH	ENSG00000089472	5.02380154496451	[]	[]	8	hSpCas9	negative selection	3515402
66200569	66200592	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCCAGGCTGGACATGTGCAAGGG	HEPH	ENSG00000089472	3.97410871745193	[]	[]	6	hSpCas9	negative selection	3515403
66192223	66192246	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATAGTCCCATTGAATCTCATGGG	HEPH	ENSG00000089472	-1.71622476574802	[]	[]	-2	hSpCas9	negative selection	3515404
66195117	66195140	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGTGGGTGACACCATTCAGGTGG	HEPH	ENSG00000089472	4.80472646227702	[]	[]	7	hSpCas9	negative selection	3515405
66198999	66199022	X	+	26780180	A375	viability (Avana lentiGuide)	AGGGCTTCCAAGACTCCAATCGG	HEPH	ENSG00000089472	-3.59611864545867	[]	[]	-6	hSpCas9	negative selection	3624059
66189803	66189826	X	+	26780180	A375	viability (Avana lentiGuide)	GGACAGATGCTGACTACCCGTGG	HEPH	ENSG00000089472	2.06264882131081	[]	[]	2	hSpCas9	negative selection	3624060
66189884	66189907	X	-	26780180	A375	viability (Avana lentiGuide)	AACCAGGTACCAGGTTCCCAGGG	HEPH	ENSG00000089472	-2.5183989736376	[]	[]	-4	hSpCas9	negative selection	3624061
66200569	66200592	X	+	26780180	A375	viability (Avana lentiGuide)	CCCAGGCTGGACATGTGCAAGGG	HEPH	ENSG00000089472	0.929416483012274	[]	[]	1	hSpCas9	negative selection	3624062
66192223	66192246	X	-	26780180	A375	viability (Avana lentiGuide)	ATAGTCCCATTGAATCTCATGGG	HEPH	ENSG00000089472	-3.16516641814026	[]	[]	-5	hSpCas9	negative selection	3624063
66195117	66195140	X	+	26780180	A375	viability (Avana lentiGuide)	GGTGGGTGACACCATTCAGGTGG	HEPH	ENSG00000089472	-1.7787890416388	[]	[]	-3	hSpCas9	negative selection	3624064
66198999	66199022	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGGGCTTCCAAGACTCCAATCGG	HEPH	ENSG00000089472	-0.2122075821658544	[4]	[4,3]	-3	hSpCas9	positive selection	3732718
66189803	66189826	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGACAGATGCTGACTACCCGTGG	HEPH	ENSG00000089472	0.27683297737136436	[5]	[7,6]	7	hSpCas9	positive selection	3732719
66189884	66189907	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AACCAGGTACCAGGTTCCCAGGG	HEPH	ENSG00000089472	0.14802080998872902	[5]	[6,5]	4	hSpCas9	positive selection	3732720
66200569	66200592	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCCAGGCTGGACATGTGCAAGGG	HEPH	ENSG00000089472	0.27745374636881603	[4]	[5,5]	7	hSpCas9	positive selection	3732721
66192223	66192246	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATAGTCCCATTGAATCTCATGGG	HEPH	ENSG00000089472	-0.2945308544025031	[6]	[5,4]	-4	hSpCas9	positive selection	3732722
66195117	66195140	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTGGGTGACACCATTCAGGTGG	HEPH	ENSG00000089472	0.27155278540498784	[5]	[6,6]	7	hSpCas9	positive selection	3732723
66198999	66199022	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGGGCTTCCAAGACTCCAATCGG	HEPH	ENSG00000089472	-0.12771746532790376	[5]	[2,5]	-2	hSpCas9	positive selection	3841325
66189803	66189826	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGACAGATGCTGACTACCCGTGG	HEPH	ENSG00000089472	0.07531629941548265	[6]	[6,4]	1	hSpCas9	positive selection	3841326
66189884	66189907	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AACCAGGTACCAGGTTCCCAGGG	HEPH	ENSG00000089472	0.15057180649575805	[5]	[5,5]	3	hSpCas9	positive selection	3841327
66200569	66200592	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCCAGGCTGGACATGTGCAAGGG	HEPH	ENSG00000089472	0.18561396096920915	[5]	[5,4]	4	hSpCas9	positive selection	3841328
66192223	66192246	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATAGTCCCATTGAATCTCATGGG	HEPH	ENSG00000089472	0.3480122577488603	[5]	[6,6]	8	hSpCas9	positive selection	3841329
66195117	66195140	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTGGGTGACACCATTCAGGTGG	HEPH	ENSG00000089472	0.24961940644820413	[6]	[6,6]	6	hSpCas9	positive selection	3841330
66173747	66173770	X	+	26780180	A375	viability	GCTCCACGAGACATTGCAACTGG	HEPH	ENSG00000089472	1.69025707114247	[]	[]	9	hSpCas9	negative selection	3947396
66173649	66173672	X	+	26780180	A375	viability	GGGGCAGCCATATCTACAACTGG	HEPH	ENSG00000089472	0.922430556995332	[]	[]	4	hSpCas9	negative selection	3947397
66172543	66172566	X	-	26780180	A375	viability	GTGGATGGTATAGGGACGAGTGG	HEPH	ENSG00000089472	0.441834354693081	[]	[]	1	hSpCas9	negative selection	3947398
66173721	66173744	X	-	26780180	A375	viability	TACATGAGAATGGTAGATCCAGG	HEPH	ENSG00000089472	1.25704894744496	[]	[]	6	hSpCas9	negative selection	3947399
66172388	66172411	X	-	26780180	A375	viability	TCTTGTAGGTTCCCCCTATCCGG	HEPH	ENSG00000089472	0.370293619976392	[]	[]	0	hSpCas9	negative selection	3947400
66173645	66173668	X	-	26780180	A375	viability	TTGTAGATATGGCTGCCCCCCGG	HEPH	ENSG00000089472	1.0915118504769	[]	[]	5	hSpCas9	negative selection	3947401
66173747	66173770	X	+	26780180	HT29	viability (GeCKOv2 library)	GCTCCACGAGACATTGCAACTGG	HEPH	ENSG00000089472	2.62306059451038	[]	[]	9	hSpCas9	negative selection	4055362
66173649	66173672	X	+	26780180	HT29	viability (GeCKOv2 library)	GGGGCAGCCATATCTACAACTGG	HEPH	ENSG00000089472	1.00157297663099	[]	[]	4	hSpCas9	negative selection	4055363
66172543	66172566	X	-	26780180	HT29	viability (GeCKOv2 library)	GTGGATGGTATAGGGACGAGTGG	HEPH	ENSG00000089472	0.393445475335753	[]	[]	1	hSpCas9	negative selection	4055364
66173721	66173744	X	-	26780180	HT29	viability (GeCKOv2 library)	TACATGAGAATGGTAGATCCAGG	HEPH	ENSG00000089472	1.07184630767696	[]	[]	5	hSpCas9	negative selection	4055365
66172388	66172411	X	-	26780180	HT29	viability (GeCKOv2 library)	TCTTGTAGGTTCCCCCTATCCGG	HEPH	ENSG00000089472	0.780560185073199	[]	[]	3	hSpCas9	negative selection	4055366
66173645	66173668	X	-	26780180	HT29	viability (GeCKOv2 library)	TTGTAGATATGGCTGCCCCCCGG	HEPH	ENSG00000089472	1.13983609621349	[]	[]	5	hSpCas9	negative selection	4055367
66189916	66189939	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTCGAAAGTGACTGTTCACTTGG	HEPH	ENSG00000089472	0.12672754374361395	[3]	[1,3]	3	hSpCas9	positive selection	4142250
66189747	66189770	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCCCATGCCAAACAAGTGCCAGG	HEPH	ENSG00000089472	-0.019587478036119266	[2]	[2,0]	0	hSpCas9	positive selection	4142251
66173747	66173770	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCTCCACGAGACATTGCAACTGG	HEPH	ENSG00000089472	0.6600533105528312	[4]	[5,3]	9	hSpCas9	positive selection	4142252
66173790	66173813	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGGACCTGTACCTCTTTTACAGG	HEPH	ENSG00000089472	-0.03819931713652697	[4]	[2,2]	-1	hSpCas9	positive selection	4142254
66172543	66172566	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTGGATGGTATAGGGACGAGTGG	HEPH	ENSG00000089472	0.22094347205851655	[4]	[3,4]	5	hSpCas9	positive selection	4142255
66172388	66172411	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCTTGTAGGTTCCCCCTATCCGG	HEPH	ENSG00000089472	0.22776405030979413	[5]	[3,4]	6	hSpCas9	positive selection	4142256
66189916	66189939	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTCGAAAGTGACTGTTCACTTGG	HEPH	ENSG00000089472	1.1316047498909132	[2]	[0,0,2,3]	8	hSpCas9	positive selection	4206272
66189747	66189770	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCCCATGCCAAACAAGTGCCAGG	HEPH	ENSG00000089472	0.49751261713787825	[3]	[4,1,4,0]	3	hSpCas9	positive selection	4206273
66173747	66173770	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCTCCACGAGACATTGCAACTGG	HEPH	ENSG00000089472	-0.4991082168878543	[5]	[0,3,2,0]	-7	hSpCas9	positive selection	4206274
66173790	66173813	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGGACCTGTACCTCTTTTACAGG	HEPH	ENSG00000089472	1.1722466656144555	[3]	[1,1,3,3]	8	hSpCas9	positive selection	4206276
66172543	66172566	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTGGATGGTATAGGGACGAGTGG	HEPH	ENSG00000089472	0.6649429868401018	[4]	[0,0,2,3]	4	hSpCas9	positive selection	4206277
66172388	66172411	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCTTGTAGGTTCCCCCTATCCGG	HEPH	ENSG00000089472	0.36849244329536784	[5]	[1,5,5,0]	2	hSpCas9	positive selection	4206278
66172388	66172411	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTTGTAGGTTCCCCCTATCCGG	HEPH	ENSG00000089472	0.24460153010093394	[3]	[3,2]	5	hSpCas9	positive selection	4274823
66172543	66172566	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTGGATGGTATAGGGACGAGTGG	HEPH	ENSG00000089472	0.2107595382277746	[0]	[1,0]	4	hSpCas9	positive selection	4274824
66173649	66173672	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGGGCAGCCATATCTACAACTGG	HEPH	ENSG00000089472	-0.03915714717403873	[1]	[1,0]	0	hSpCas9	positive selection	4274825
66173747	66173770	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCTCCACGAGACATTGCAACTGG	HEPH	ENSG00000089472	-1.1062034664052374	[2]	[0,0]	-9	hSpCas9	positive selection	4339084
66173645	66173668	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTGTAGATATGGCTGCCCCCCGG	HEPH	ENSG00000089472	-0.049508405774605746	[4]	[3,2]	-1	hSpCas9	positive selection	4339085
66173721	66173744	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TACATGAGAATGGTAGATCCAGG	HEPH	ENSG00000089472	-0.23412524131837997	[4]	[2,2]	-5	hSpCas9	positive selection	4339086
66189858	66189880	X	-	27760321	OCIAML3	viability	ATCTCAGCAGTCACAAAGGTGG	HEPH	ENSG00000089472	0.01288145167445498	[324,242]	[173,284]	0	hSpCas9	negative selection	4406622
66189893	66189915	X	-	27760321	OCIAML3	viability	AGCTAATTAACCAGGTACCAGG	HEPH	ENSG00000089472	-0.34153544600075514	[278,218]	[110,206]	-4	hSpCas9	negative selection	4406623
66192235	66192257	X	+	27760321	OCIAML3	viability	AATGGGACTATGGCCCGATGGG	HEPH	ENSG00000089472	0.7683676194066379	[593,467]	[582,858]	8	hSpCas9	negative selection	4406624
66193522	66193544	X	+	27760321	OCIAML3	viability	AGAAGAGCTCCAGCCGAATTGG	HEPH	ENSG00000089472	0.5521097674002496	[452,347]	[345,598]	6	hSpCas9	negative selection	4406625
66195128	66195150	X	-	27760321	OCIAML3	viability	TTGTAGAAGACCACCTGAATGG	HEPH	ENSG00000089472	-0.650130067792686	[1,1]	[0,0]	-6	hSpCas9	negative selection	4406626
66189858	66189880	X	-	27760321	OCIAML2	viability	ATCTCAGCAGTCACAAAGGTGG	HEPH	ENSG00000089472	-0.26099470963644567	[324,242]	[177,205]	-3	hSpCas9	negative selection	4490085
66189893	66189915	X	-	27760321	OCIAML2	viability	AGCTAATTAACCAGGTACCAGG	HEPH	ENSG00000089472	0.36045683049486527	[278,218]	[271,236]	5	hSpCas9	negative selection	4490086
66192235	66192257	X	+	27760321	OCIAML2	viability	AATGGGACTATGGCCCGATGGG	HEPH	ENSG00000089472	0.47922445750431386	[593,467]	[603,582]	6	hSpCas9	negative selection	4490087
66193522	66193544	X	+	27760321	OCIAML2	viability	AGAAGAGCTCCAGCCGAATTGG	HEPH	ENSG00000089472	0.15542385559339625	[452,347]	[336,385]	2	hSpCas9	negative selection	4490088
66195128	66195150	X	-	27760321	OCIAML2	viability	TTGTAGAAGACCACCTGAATGG	HEPH	ENSG00000089472	-0.6988754330577347	[1,1]	[0,0]	-6	hSpCas9	negative selection	4490089
66189858	66189880	X	-	27760321	MV411	viability	ATCTCAGCAGTCACAAAGGTGG	HEPH	ENSG00000089472	-1.8824089925933556	[324,242]	[45,56]	-8	hSpCas9	negative selection	4573548
66189893	66189915	X	-	27760321	MV411	viability	AGCTAATTAACCAGGTACCAGG	HEPH	ENSG00000089472	-0.8112166920803403	[278,218]	[122,47]	-5	hSpCas9	negative selection	4573549
66192235	66192257	X	+	27760321	MV411	viability	AATGGGACTATGGCCCGATGGG	HEPH	ENSG00000089472	1.3462249827228092	[593,467]	[1060,620]	8	hSpCas9	negative selection	4573550
66193522	66193544	X	+	27760321	MV411	viability	AGAAGAGCTCCAGCCGAATTGG	HEPH	ENSG00000089472	0.26134842339685216	[452,347]	[84,658]	1	hSpCas9	negative selection	4573551
66195128	66195150	X	-	27760321	MV411	viability	TTGTAGAAGACCACCTGAATGG	HEPH	ENSG00000089472	-0.40505149887800407	[1,1]	[0,0]	-3	hSpCas9	negative selection	4573552
66189858	66189880	X	-	27760321	HL60	viability	ATCTCAGCAGTCACAAAGGTGG	HEPH	ENSG00000089472	0.11900162733077313	[324,242]	[225,274]	1	hSpCas9	negative selection	4657011
66189893	66189915	X	-	27760321	HL60	viability	AGCTAATTAACCAGGTACCAGG	HEPH	ENSG00000089472	0.37278565550814663	[278,218]	[232,291]	4	hSpCas9	negative selection	4657012
66192235	66192257	X	+	27760321	HL60	viability	AATGGGACTATGGCCCGATGGG	HEPH	ENSG00000089472	1.1611281901630122	[593,467]	[922,1006]	9	hSpCas9	negative selection	4657013
66193522	66193544	X	+	27760321	HL60	viability	AGAAGAGCTCCAGCCGAATTGG	HEPH	ENSG00000089472	0.48972111028312093	[452,347]	[470,439]	6	hSpCas9	negative selection	4657014
66195128	66195150	X	-	27760321	HL60	viability	TTGTAGAAGACCACCTGAATGG	HEPH	ENSG00000089472	-0.7129216606721407	[1,1]	[0,0]	-6	hSpCas9	negative selection	4657015
66189858	66189880	X	-	27760321	HT1080	viability	ATCTCAGCAGTCACAAAGGTGG	HEPH	ENSG00000089472	-1.5907293400695057	[242,189]	[20,36]	-5	hSpCas9	negative selection	4740474
66189893	66189915	X	-	27760321	HT1080	viability	AGCTAATTAACCAGGTACCAGG	HEPH	ENSG00000089472	1.142261348047128	[218,170]	[212,125]	6	hSpCas9	negative selection	4740475
66192235	66192257	X	+	27760321	HT1080	viability	AATGGGACTATGGCCCGATGGG	HEPH	ENSG00000089472	0.8713013165197897	[467,364]	[250,360]	5	hSpCas9	negative selection	4740476
66193522	66193544	X	+	27760321	HT1080	viability	AGAAGAGCTCCAGCCGAATTGG	HEPH	ENSG00000089472	1.2440864625035444	[347,271]	[282,302]	6	hSpCas9	negative selection	4740477
66195128	66195150	X	-	27760321	HT1080	viability	TTGTAGAAGACCACCTGAATGG	HEPH	ENSG00000089472	1.5878039934530204	[1,1]	[0,3]	8	hSpCas9	negative selection	4740478
66189858	66189880	X	-	27760321	HT29	viability after 7 days	ATCTCAGCAGTCACAAAGGTGG	HEPH	ENSG00000089472	-0.05009330346827923	[242,189]	[294,277,237]	0	hSpCas9	negative selection	4823937
66189893	66189915	X	-	27760321	HT29	viability after 7 days	AGCTAATTAACCAGGTACCAGG	HEPH	ENSG00000089472	-0.31783589572450854	[218,170]	[258,233,120]	-4	hSpCas9	negative selection	4823938
66192235	66192257	X	+	27760321	HT29	viability after 7 days	AATGGGACTATGGCCCGATGGG	HEPH	ENSG00000089472	0.1548241973621712	[467,364]	[525,637,612]	2	hSpCas9	negative selection	4823939
66193522	66193544	X	+	27760321	HT29	viability after 7 days	AGAAGAGCTCCAGCCGAATTGG	HEPH	ENSG00000089472	0.1543480572249747	[347,271]	[510,549,283]	2	hSpCas9	negative selection	4823940
66195128	66195150	X	-	27760321	HT29	viability after 7 days	TTGTAGAAGACCACCTGAATGG	HEPH	ENSG00000089472	-1.3840325596302083	[1,1]	[0,0,0]	-9	hSpCas9	negative selection	4823941
66189858	66189880	X	-	27760321	HT29	viability after 25 days	ATCTCAGCAGTCACAAAGGTGG	HEPH	ENSG00000089472	0.013295944159388173	[242,189]	[120,178,480]	0	hSpCas9	negative selection	4907400
66189893	66189915	X	-	27760321	HT29	viability after 25 days	AGCTAATTAACCAGGTACCAGG	HEPH	ENSG00000089472	0.3694007021911321	[218,170]	[366,239,246]	4	hSpCas9	negative selection	4907401
66192235	66192257	X	+	27760321	HT29	viability after 25 days	AATGGGACTATGGCCCGATGGG	HEPH	ENSG00000089472	0.3309427665385559	[467,364]	[758,513,501]	3	hSpCas9	negative selection	4907402
66193522	66193544	X	+	27760321	HT29	viability after 25 days	AGAAGAGCTCCAGCCGAATTGG	HEPH	ENSG00000089472	0.9878834794185414	[347,271]	[552,829,736]	9	hSpCas9	negative selection	4907403
66195128	66195150	X	-	27760321	HT29	viability after 25 days	TTGTAGAAGACCACCTGAATGG	HEPH	ENSG00000089472	-1.214054570927468	[1,1]	[0,0,0]	-7	hSpCas9	negative selection	4907404
66189858	66189880	X	-	27760321	HT29	viability after 22 days	ATCTCAGCAGTCACAAAGGTGG	HEPH	ENSG00000089472	-0.2516252256816204	[242,189]	[69,200,364]	-3	hSpCas9	negative selection	4990863
66189893	66189915	X	-	27760321	HT29	viability after 22 days	AGCTAATTAACCAGGTACCAGG	HEPH	ENSG00000089472	0.5596737298958478	[218,170]	[498,402,87]	6	hSpCas9	negative selection	4990864
66192235	66192257	X	+	27760321	HT29	viability after 22 days	AATGGGACTATGGCCCGATGGG	HEPH	ENSG00000089472	0.5250140320615311	[467,364]	[623,896,557]	6	hSpCas9	negative selection	4990865
66193522	66193544	X	+	27760321	HT29	viability after 22 days	AGAAGAGCTCCAGCCGAATTGG	HEPH	ENSG00000089472	0.7220098125235512	[347,271]	[555,677,539]	7	hSpCas9	negative selection	4990866
66195128	66195150	X	-	27760321	HT29	viability after 22 days	TTGTAGAAGACCACCTGAATGG	HEPH	ENSG00000089472	-1.2313732027867275	[1,1]	[0,0,0]	-7	hSpCas9	negative selection	4990867
66189858	66189880	X	-	27760321	HT29	viability after 19 days	ATCTCAGCAGTCACAAAGGTGG	HEPH	ENSG00000089472	-0.7615314503395711	[242,189]	[192,129,120]	-6	hSpCas9	negative selection	5074326
66189893	66189915	X	-	27760321	HT29	viability after 19 days	AGCTAATTAACCAGGTACCAGG	HEPH	ENSG00000089472	0.8013545285193258	[218,170]	[324,335,493]	8	hSpCas9	negative selection	5074327
66192235	66192257	X	+	27760321	HT29	viability after 19 days	AATGGGACTATGGCCCGATGGG	HEPH	ENSG00000089472	0.9066797572921016	[467,364]	[955,1186,554]	8	hSpCas9	negative selection	5074328
66193522	66193544	X	+	27760321	HT29	viability after 19 days	AGAAGAGCTCCAGCCGAATTGG	HEPH	ENSG00000089472	0.4645702404214049	[347,271]	[658,597,237]	4	hSpCas9	negative selection	5074329
66195128	66195150	X	-	27760321	HT29	viability after 19 days	TTGTAGAAGACCACCTGAATGG	HEPH	ENSG00000089472	-1.2155331503635143	[1,1]	[0,0,0]	-7	hSpCas9	negative selection	5074330
66189858	66189880	X	-	27760321	HT29	viability after 16 days	ATCTCAGCAGTCACAAAGGTGG	HEPH	ENSG00000089472	0.49179069736290043	[242,189]	[141,306,554]	5	hSpCas9	negative selection	5157789
66189893	66189915	X	-	27760321	HT29	viability after 16 days	AGCTAATTAACCAGGTACCAGG	HEPH	ENSG00000089472	-0.22574891780412998	[218,170]	[231,108,224]	-3	hSpCas9	negative selection	5157790
66192235	66192257	X	+	27760321	HT29	viability after 16 days	AATGGGACTATGGCCCGATGGG	HEPH	ENSG00000089472	0.6017662286869986	[467,364]	[662,787,663]	7	hSpCas9	negative selection	5157791
66193522	66193544	X	+	27760321	HT29	viability after 16 days	AGAAGAGCTCCAGCCGAATTGG	HEPH	ENSG00000089472	0.4939993672759385	[347,271]	[395,437,623]	5	hSpCas9	negative selection	5157792
66195128	66195150	X	-	27760321	HT29	viability after 16 days	TTGTAGAAGACCACCTGAATGG	HEPH	ENSG00000089472	-1.1840686979425925	[1,1]	[0,0,0]	-7	hSpCas9	negative selection	5157793
66189858	66189880	X	-	27760321	HT29	viability after 13 days	ATCTCAGCAGTCACAAAGGTGG	HEPH	ENSG00000089472	0.4950081871820964	[242,189]	[464,366,236]	6	hSpCas9	negative selection	5241252
66189893	66189915	X	-	27760321	HT29	viability after 13 days	AGCTAATTAACCAGGTACCAGG	HEPH	ENSG00000089472	0.37376506294087675	[218,170]	[197,395,285]	5	hSpCas9	negative selection	5241253
66192235	66192257	X	+	27760321	HT29	viability after 13 days	AATGGGACTATGGCCCGATGGG	HEPH	ENSG00000089472	0.43011669472496505	[467,364]	[788,571,594]	5	hSpCas9	negative selection	5241254
66193522	66193544	X	+	27760321	HT29	viability after 13 days	AGAAGAGCTCCAGCCGAATTGG	HEPH	ENSG00000089472	1.00072736319464	[347,271]	[886,763,519]	9	hSpCas9	negative selection	5241255
66195128	66195150	X	-	27760321	HT29	viability after 13 days	TTGTAGAAGACCACCTGAATGG	HEPH	ENSG00000089472	-1.2363560973867305	[1,1]	[0,0,0]	-8	hSpCas9	negative selection	5241256
66189858	66189880	X	-	27760321	HT29	viability after 10 days	ATCTCAGCAGTCACAAAGGTGG	HEPH	ENSG00000089472	-0.262194818725909	[242,189]	[71,389,218]	-3	hSpCas9	negative selection	5324715
66189893	66189915	X	-	27760321	HT29	viability after 10 days	AGCTAATTAACCAGGTACCAGG	HEPH	ENSG00000089472	0.4447765323111899	[218,170]	[276,292,420]	6	hSpCas9	negative selection	5324716
66192235	66192257	X	+	27760321	HT29	viability after 10 days	AATGGGACTATGGCCCGATGGG	HEPH	ENSG00000089472	0.42818126396654044	[467,364]	[967,500,625]	6	hSpCas9	negative selection	5324717
66193522	66193544	X	+	27760321	HT29	viability after 10 days	AGAAGAGCTCCAGCCGAATTGG	HEPH	ENSG00000089472	0.38561122716260965	[347,271]	[357,711,453]	5	hSpCas9	negative selection	5324718
66195128	66195150	X	-	27760321	HT29	viability after 10 days	TTGTAGAAGACCACCTGAATGG	HEPH	ENSG00000089472	-1.3423674045470744	[1,1]	[0,0,0]	-8	hSpCas9	negative selection	5324719
66189858	66189880	X	-	27760321	MOLM13	viability	ATCTCAGCAGTCACAAAGGTGG	HEPH	ENSG00000089472	-0.038862058676568334	[324,242]	[98,201]	0	hSpCas9	negative selection	5408178
66189893	66189915	X	-	27760321	MOLM13	viability	AGCTAATTAACCAGGTACCAGG	HEPH	ENSG00000089472	2.7562558176004064	[278,218]	[69,1685]	9	hSpCas9	negative selection	5408179
66192235	66192257	X	+	27760321	MOLM13	viability	AATGGGACTATGGCCCGATGGG	HEPH	ENSG00000089472	1.4572874875340083	[593,467]	[711,906]	8	hSpCas9	negative selection	5408180
66193522	66193544	X	+	27760321	MOLM13	viability	AGAAGAGCTCCAGCCGAATTGG	HEPH	ENSG00000089472	0.7062631353332923	[452,347]	[588,175]	5	hSpCas9	negative selection	5408181
66195128	66195150	X	-	27760321	MOLM13	viability	TTGTAGAAGACCACCTGAATGG	HEPH	ENSG00000089472	-0.1789946860504088	[1,1]	[0,0]	-1	hSpCas9	negative selection	5408182
66164616	66164639	X	+	27661255	K562	viability	GGAAAGTTAAAGGAGACAATAGG	HEPH	ENSG00000089472	-0.0222257650600981	[1995,1608]	[1513,1345]	-1	dCas9-KRAB	negative selection	5484442
66172388	66172411	X	-	27260156	BXPC3	viability	TCTTGTAGGTTCCCCCTATCCGG	HEPH	ENSG00000089472	0.4583199878828936	[608]	[833,764,1099,799]	8	hSpCas9	negative selection	5547283
66172543	66172566	X	-	27260156	BXPC3	viability	GTGGATGGTATAGGGACGAGTGG	HEPH	ENSG00000089472	0.64914515913041	[62]	[108,137,82,75]	9	hSpCas9	negative selection	5547284
66173649	66173672	X	+	27260156	BXPC3	viability	GGGGCAGCCATATCTACAACTGG	HEPH	ENSG00000089472	0.2544541722804954	[131]	[129,196,202,124]	5	hSpCas9	negative selection	5547285
66173747	66173770	X	+	27260156	BXPC3	viability	GCTCCACGAGACATTGCAACTGG	HEPH	ENSG00000089472	-0.11206471824463549	[228]	[138,288,173,295]	-3	hSpCas9	negative selection	5611544
66173645	66173668	X	-	27260156	BXPC3	viability	TTGTAGATATGGCTGCCCCCCGG	HEPH	ENSG00000089472	-0.0812435881468998	[1040]	[891,1057,1064,1117]	-2	hSpCas9	negative selection	5611545
66173721	66173744	X	-	27260156	BXPC3	viability	TACATGAGAATGGTAGATCCAGG	HEPH	ENSG00000089472	0.04972129944234549	[1140]	[1160,1209,1029,1577]	1	hSpCas9	negative selection	5611546
66172388	66172411	X	-	27260156	A673	viability	TCTTGTAGGTTCCCCCTATCCGG	HEPH	ENSG00000089472	0.24661604074754556	[608]	[851,827,952,831]	6	hSpCas9	negative selection	5668534
66172543	66172566	X	-	27260156	A673	viability	GTGGATGGTATAGGGACGAGTGG	HEPH	ENSG00000089472	0.6753517011624233	[62]	[128,164,71,116]	9	hSpCas9	negative selection	5668535
66173649	66173672	X	+	27260156	A673	viability	GGGGCAGCCATATCTACAACTGG	HEPH	ENSG00000089472	-0.014901771630192018	[131]	[138,128,162,196]	0	hSpCas9	negative selection	5668536
66173747	66173770	X	+	27260156	A673	viability	GCTCCACGAGACATTGCAACTGG	HEPH	ENSG00000089472	0.019581977126945205	[228]	[314,247,267,288]	0	hSpCas9	negative selection	5732795
66173645	66173668	X	-	27260156	A673	viability	TTGTAGATATGGCTGCCCCCCGG	HEPH	ENSG00000089472	-0.10713647838871343	[1040]	[1264,1142,1067,1177]	-3	hSpCas9	negative selection	5732796
66173721	66173744	X	-	27260156	A673	viability	TACATGAGAATGGTAGATCCAGG	HEPH	ENSG00000089472	-0.060670183249767584	[1140]	[1394,1214,1347,1304]	-1	hSpCas9	negative selection	5732797
66172388	66172411	X	-	27260156	A375	viability	TCTTGTAGGTTCCCCCTATCCGG	HEPH	ENSG00000089472	0.6771993684025801	[608]	[1231,1392,990,983]	8	hSpCas9	negative selection	5789785
66172543	66172566	X	-	27260156	A375	viability	GTGGATGGTATAGGGACGAGTGG	HEPH	ENSG00000089472	0.1992587624510933	[62]	[79,103,59,94]	3	hSpCas9	negative selection	5789786
66173649	66173672	X	+	27260156	A375	viability	GGGGCAGCCATATCTACAACTGG	HEPH	ENSG00000089472	0.35231852996288926	[131]	[215,224,128,217]	5	hSpCas9	negative selection	5789787
66173747	66173770	X	+	27260156	A375	viability	GCTCCACGAGACATTGCAACTGG	HEPH	ENSG00000089472	-0.023161348597664944	[228]	[125,333,275,317]	0	hSpCas9	negative selection	5854046
66173645	66173668	X	-	27260156	A375	viability	TTGTAGATATGGCTGCCCCCCGG	HEPH	ENSG00000089472	-0.08311284896492421	[1040]	[1001,1397,1289,953]	-1	hSpCas9	negative selection	5854047
66173721	66173744	X	-	27260156	A375	viability	TACATGAGAATGGTAGATCCAGG	HEPH	ENSG00000089472	0.11407300213631988	[1140]	[1324,1728,1604,1175]	1	hSpCas9	negative selection	5854048
66172388	66172411	X	-	27260156	COLO741	viability	TCTTGTAGGTTCCCCCTATCCGG	HEPH	ENSG00000089472	0.29756761444095176	[608]	[1219,868,810]	6	hSpCas9	negative selection	5911036
66172543	66172566	X	-	27260156	COLO741	viability	GTGGATGGTATAGGGACGAGTGG	HEPH	ENSG00000089472	0.6839217819731718	[62]	[212,85,97]	9	hSpCas9	negative selection	5911037
66173649	66173672	X	+	27260156	COLO741	viability	GGGGCAGCCATATCTACAACTGG	HEPH	ENSG00000089472	-0.18056715188371286	[131]	[164,196,89]	-4	hSpCas9	negative selection	5911038
66173747	66173770	X	+	27260156	COLO741	viability	GCTCCACGAGACATTGCAACTGG	HEPH	ENSG00000089472	-0.12074337878281938	[228]	[224,335,243]	-3	hSpCas9	negative selection	5975297
66173645	66173668	X	-	27260156	COLO741	viability	TTGTAGATATGGCTGCCCCCCGG	HEPH	ENSG00000089472	-0.03827118419843689	[1040]	[1406,1354,1141]	-1	hSpCas9	negative selection	5975298
66173721	66173744	X	-	27260156	COLO741	viability	TACATGAGAATGGTAGATCCAGG	HEPH	ENSG00000089472	-0.0666510158967899	[1140]	[1372,1483,1319]	-1	hSpCas9	negative selection	5975299
66172388	66172411	X	-	27260156	CAL120	viability	TCTTGTAGGTTCCCCCTATCCGG	HEPH	ENSG00000089472	0.8023410984914165	[608]	[1781,955,1295]	9	hSpCas9	negative selection	6032287
66172543	66172566	X	-	27260156	CAL120	viability	GTGGATGGTATAGGGACGAGTGG	HEPH	ENSG00000089472	-0.578732206159204	[62]	[94,24,43]	-7	hSpCas9	negative selection	6032288
66173649	66173672	X	+	27260156	CAL120	viability	GGGGCAGCCATATCTACAACTGG	HEPH	ENSG00000089472	0.1258899587731681	[131]	[156,125,249]	2	hSpCas9	negative selection	6032289
66173747	66173770	X	+	27260156	CAL120	viability	GCTCCACGAGACATTGCAACTGG	HEPH	ENSG00000089472	-0.14458355475503626	[228]	[188,264,307]	-2	hSpCas9	negative selection	6096548
66173645	66173668	X	-	27260156	CAL120	viability	TTGTAGATATGGCTGCCCCCCGG	HEPH	ENSG00000089472	-0.015558545213818498	[1040]	[1594,1116,1180]	0	hSpCas9	negative selection	6096549
66173721	66173744	X	-	27260156	CAL120	viability	TACATGAGAATGGTAGATCCAGG	HEPH	ENSG00000089472	0.06017668155903344	[1140]	[1361,1884,1180]	0	hSpCas9	negative selection	6096550
66172388	66172411	X	-	27260156	CADOES1	viability	TCTTGTAGGTTCCCCCTATCCGG	HEPH	ENSG00000089472	0.6593449599087173	[608]	[719,963,867,1031]	9	hSpCas9	negative selection	6153538
66172543	66172566	X	-	27260156	CADOES1	viability	GTGGATGGTATAGGGACGAGTGG	HEPH	ENSG00000089472	0.40715058215658395	[62]	[52,70,104,81]	6	hSpCas9	negative selection	6153539
66173649	66173672	X	+	27260156	CADOES1	viability	GGGGCAGCCATATCTACAACTGG	HEPH	ENSG00000089472	0.42630598964879773	[131]	[223,171,143,117]	7	hSpCas9	negative selection	6153540
66173747	66173770	X	+	27260156	CADOES1	viability	GCTCCACGAGACATTGCAACTGG	HEPH	ENSG00000089472	0.25765713730987316	[228]	[195,250,256,316]	4	hSpCas9	negative selection	6217799
66173645	66173668	X	-	27260156	CADOES1	viability	TTGTAGATATGGCTGCCCCCCGG	HEPH	ENSG00000089472	-0.19603981773671186	[1040]	[844,928,809,794]	-3	hSpCas9	negative selection	6217800
66173721	66173744	X	-	27260156	CADOES1	viability	TACATGAGAATGGTAGATCCAGG	HEPH	ENSG00000089472	0.15837911005081073	[1140]	[1142,1070,1087,1444]	2	hSpCas9	negative selection	6217801
66172388	66172411	X	-	27260156	EWS502	viability	TCTTGTAGGTTCCCCCTATCCGG	HEPH	ENSG00000089472	0.49519814236084786	[608]	[727,1007,919,1001]	8	hSpCas9	negative selection	6274789
66172543	66172566	X	-	27260156	EWS502	viability	GTGGATGGTATAGGGACGAGTGG	HEPH	ENSG00000089472	0.7096798308160852	[62]	[73,71,106,194]	9	hSpCas9	negative selection	6274790
66173649	66173672	X	+	27260156	EWS502	viability	GGGGCAGCCATATCTACAACTGG	HEPH	ENSG00000089472	0.5542172468876638	[131]	[109,202,211,314]	8	hSpCas9	negative selection	6274791
66173747	66173770	X	+	27260156	EWS502	viability	GCTCCACGAGACATTGCAACTGG	HEPH	ENSG00000089472	0.11246013608700756	[228]	[197,221,245,400]	2	hSpCas9	negative selection	6339050
66173645	66173668	X	-	27260156	EWS502	viability	TTGTAGATATGGCTGCCCCCCGG	HEPH	ENSG00000089472	-0.12926424513302415	[1040]	[974,935,1149,973]	-2	hSpCas9	negative selection	6339051
66173721	66173744	X	-	27260156	EWS502	viability	TACATGAGAATGGTAGATCCAGG	HEPH	ENSG00000089472	-0.026891443445657748	[1140]	[1184,1062,1282,1217]	0	hSpCas9	negative selection	6339052
66172388	66172411	X	-	27260156	EW8	viability	TCTTGTAGGTTCCCCCTATCCGG	HEPH	ENSG00000089472	0.44077549299471447	[608]	[671,664,764,559]	7	hSpCas9	negative selection	6396040
66172543	66172566	X	-	27260156	EW8	viability	GTGGATGGTATAGGGACGAGTGG	HEPH	ENSG00000089472	0.2062696748133548	[62]	[43,48,50,90]	4	hSpCas9	negative selection	6396041
66173649	66173672	X	+	27260156	EW8	viability	GGGGCAGCCATATCTACAACTGG	HEPH	ENSG00000089472	0.02110284991811673	[131]	[167,126,94,52]	0	hSpCas9	negative selection	6396042
66173747	66173770	X	+	27260156	EW8	viability	GCTCCACGAGACATTGCAACTGG	HEPH	ENSG00000089472	0.0013076546542822864	[228]	[182,191,204,158]	0	hSpCas9	negative selection	6460301
66173645	66173668	X	-	27260156	EW8	viability	TTGTAGATATGGCTGCCCCCCGG	HEPH	ENSG00000089472	-0.23085744755893667	[1040]	[864,747,497,815]	-4	hSpCas9	negative selection	6460302
66173721	66173744	X	-	27260156	EW8	viability	TACATGAGAATGGTAGATCCAGG	HEPH	ENSG00000089472	-0.032282444096274565	[1140]	[1140,815,869,818]	0	hSpCas9	negative selection	6460303
66172388	66172411	X	-	27260156	CORL105	viability	TCTTGTAGGTTCCCCCTATCCGG	HEPH	ENSG00000089472	0.7346450928814163	[608]	[861,1163,1393,1345]	9	hSpCas9	negative selection	6517291
66172543	66172566	X	-	27260156	CORL105	viability	GTGGATGGTATAGGGACGAGTGG	HEPH	ENSG00000089472	0.7951578453043169	[62]	[86,232,154,37]	9	hSpCas9	negative selection	6517292
66173649	66173672	X	+	27260156	CORL105	viability	GGGGCAGCCATATCTACAACTGG	HEPH	ENSG00000089472	0.27474415926420814	[131]	[169,191,261,134]	5	hSpCas9	negative selection	6517293
66173747	66173770	X	+	27260156	CORL105	viability	GCTCCACGAGACATTGCAACTGG	HEPH	ENSG00000089472	0.4283870505735913	[228]	[346,524,323,237]	7	hSpCas9	negative selection	6581552
66173645	66173668	X	-	27260156	CORL105	viability	TTGTAGATATGGCTGCCCCCCGG	HEPH	ENSG00000089472	0.02085237263137918	[1040]	[1232,1078,1357,1296]	0	hSpCas9	negative selection	6581553
66173721	66173744	X	-	27260156	CORL105	viability	TACATGAGAATGGTAGATCCAGG	HEPH	ENSG00000089472	0.06578356882322689	[1140]	[1532,1305,1501,1273]	1	hSpCas9	negative selection	6581554
66172388	66172411	X	-	27260156	HS294T	viability	TCTTGTAGGTTCCCCCTATCCGG	HEPH	ENSG00000089472	0.42745819620907394	[608]	[300,380,255,328]	6	hSpCas9	negative selection	6638542
66172543	66172566	X	-	27260156	HS294T	viability	GTGGATGGTATAGGGACGAGTGG	HEPH	ENSG00000089472	0.9891198121090061	[62]	[25,29,51,95]	9	hSpCas9	negative selection	6638543
66173649	66173672	X	+	27260156	HS294T	viability	GGGGCAGCCATATCTACAACTGG	HEPH	ENSG00000089472	-0.4080438199998977	[131]	[40,25,42,44]	-5	hSpCas9	negative selection	6638544
66173747	66173770	X	+	27260156	HS294T	viability	GCTCCACGAGACATTGCAACTGG	HEPH	ENSG00000089472	-0.20551123399281201	[228]	[65,80,72,89]	-3	hSpCas9	negative selection	6702803
66173645	66173668	X	-	27260156	HS294T	viability	TTGTAGATATGGCTGCCCCCCGG	HEPH	ENSG00000089472	-0.4915462529379495	[1040]	[269,253,290,340]	-6	hSpCas9	negative selection	6702804
66173721	66173744	X	-	27260156	HS294T	viability	TACATGAGAATGGTAGATCCAGG	HEPH	ENSG00000089472	-0.016679306434982166	[1140]	[399,317,588,444]	0	hSpCas9	negative selection	6702805
66172388	66172411	X	-	27260156	HCC44	viability	TCTTGTAGGTTCCCCCTATCCGG	HEPH	ENSG00000089472	0.675332276381365	[608]	[1424,702,1163,1192]	9	hSpCas9	negative selection	6759793
66172543	66172566	X	-	27260156	HCC44	viability	GTGGATGGTATAGGGACGAGTGG	HEPH	ENSG00000089472	0.15173186875169664	[62]	[36,58,63,149]	2	hSpCas9	negative selection	6759794
66173649	66173672	X	+	27260156	HCC44	viability	GGGGCAGCCATATCTACAACTGG	HEPH	ENSG00000089472	0.0656277601701365	[131]	[110,111,261,158]	1	hSpCas9	negative selection	6759795
66173747	66173770	X	+	27260156	HCC44	viability	GCTCCACGAGACATTGCAACTGG	HEPH	ENSG00000089472	-0.2014924559547051	[228]	[209,128,272,304]	-3	hSpCas9	negative selection	6824054
66173645	66173668	X	-	27260156	HCC44	viability	TTGTAGATATGGCTGCCCCCCGG	HEPH	ENSG00000089472	-0.23792059576220725	[1040]	[930,998,1282,820]	-4	hSpCas9	negative selection	6824055
66173721	66173744	X	-	27260156	HCC44	viability	TACATGAGAATGGTAGATCCAGG	HEPH	ENSG00000089472	-0.11648988048761022	[1140]	[1247,929,1388,1258]	-2	hSpCas9	negative selection	6824056
66172388	66172411	X	-	27260156	G402	viability	TCTTGTAGGTTCCCCCTATCCGG	HEPH	ENSG00000089472	0.6902769121647325	[608]	[1193,1628,1029,973]	8	hSpCas9	negative selection	6881044
66172543	66172566	X	-	27260156	G402	viability	GTGGATGGTATAGGGACGAGTGG	HEPH	ENSG00000089472	0.4710224749577261	[62]	[68,161,136,57]	6	hSpCas9	negative selection	6881045
66173649	66173672	X	+	27260156	G402	viability	GGGGCAGCCATATCTACAACTGG	HEPH	ENSG00000089472	0.1226506205751241	[131]	[229,141,207,128]	1	hSpCas9	negative selection	6881046
66173747	66173770	X	+	27260156	G402	viability	GCTCCACGAGACATTGCAACTGG	HEPH	ENSG00000089472	0.5190039441930975	[228]	[452,351,677,134]	6	hSpCas9	negative selection	6945305
66173645	66173668	X	-	27260156	G402	viability	TTGTAGATATGGCTGCCCCCCGG	HEPH	ENSG00000089472	-0.05473602622282869	[1040]	[1448,1276,1274,935]	0	hSpCas9	negative selection	6945306
66173721	66173744	X	-	27260156	G402	viability	TACATGAGAATGGTAGATCCAGG	HEPH	ENSG00000089472	0.14967768592131048	[1140]	[1519,2547,1321,869]	2	hSpCas9	negative selection	6945307
66172388	66172411	X	-	27260156	L33	viability	TCTTGTAGGTTCCCCCTATCCGG	HEPH	ENSG00000089472	0.5261557461009145	[608]	[896,406,525,780]	9	hSpCas9	negative selection	7002295
66172543	66172566	X	-	27260156	L33	viability	GTGGATGGTATAGGGACGAGTGG	HEPH	ENSG00000089472	0.41544071496774704	[62]	[71,36,55,84]	8	hSpCas9	negative selection	7002296
66173649	66173672	X	+	27260156	L33	viability	GGGGCAGCCATATCTACAACTGG	HEPH	ENSG00000089472	0.3394324780542062	[131]	[119,91,107,152]	7	hSpCas9	negative selection	7002297
66173747	66173770	X	+	27260156	L33	viability	GCTCCACGAGACATTGCAACTGG	HEPH	ENSG00000089472	-0.36132387761423534	[228]	[159,96,132,105]	-7	hSpCas9	negative selection	7066556
66173645	66173668	X	-	27260156	L33	viability	TTGTAGATATGGCTGCCCCCCGG	HEPH	ENSG00000089472	-0.039290340562378345	[1040]	[881,414,792,900]	-1	hSpCas9	negative selection	7066557
66173721	66173744	X	-	27260156	L33	viability	TACATGAGAATGGTAGATCCAGG	HEPH	ENSG00000089472	-0.014204278468424647	[1140]	[1096,447,648,1294]	0	hSpCas9	negative selection	7066558
66172388	66172411	X	-	27260156	K562	viability	TCTTGTAGGTTCCCCCTATCCGG	HEPH	ENSG00000089472	0.4714870551919928	[608]	[671,591,790,905]	6	hSpCas9	negative selection	7123546
66172543	66172566	X	-	27260156	K562	viability	GTGGATGGTATAGGGACGAGTGG	HEPH	ENSG00000089472	0.21645854736644798	[62]	[32,103,75,47]	2	hSpCas9	negative selection	7123547
66173649	66173672	X	+	27260156	K562	viability	GGGGCAGCCATATCTACAACTGG	HEPH	ENSG00000089472	0.14955759098577115	[131]	[87,343,49,53]	1	hSpCas9	negative selection	7123548
66173747	66173770	X	+	27260156	K562	viability	GCTCCACGAGACATTGCAACTGG	HEPH	ENSG00000089472	-0.3040539020031907	[228]	[92,156,109,277]	-4	hSpCas9	negative selection	7187807
66173645	66173668	X	-	27260156	K562	viability	TTGTAGATATGGCTGCCCCCCGG	HEPH	ENSG00000089472	-0.07781210539998584	[1040]	[825,698,1034,918]	-1	hSpCas9	negative selection	7187808
66173721	66173744	X	-	27260156	K562	viability	TACATGAGAATGGTAGATCCAGG	HEPH	ENSG00000089472	0.5809478386075939	[1140]	[1557,1489,1630,1389]	7	hSpCas9	negative selection	7187809
66172388	66172411	X	-	27260156	HT29	viability	TCTTGTAGGTTCCCCCTATCCGG	HEPH	ENSG00000089472	0.33611356267171394	[608]	[1013,878,1042,811]	6	hSpCas9	negative selection	7244797
66172543	66172566	X	-	27260156	HT29	viability	GTGGATGGTATAGGGACGAGTGG	HEPH	ENSG00000089472	0.11977583184141283	[62]	[83,119,79,54]	2	hSpCas9	negative selection	7244798
66173649	66173672	X	+	27260156	HT29	viability	GGGGCAGCCATATCTACAACTGG	HEPH	ENSG00000089472	-0.12896999171109802	[131]	[98,196,156,134]	-3	hSpCas9	negative selection	7244799
66173747	66173770	X	+	27260156	HT29	viability	GCTCCACGAGACATTGCAACTGG	HEPH	ENSG00000089472	-0.0581082009428171	[228]	[256,315,212,282]	-1	hSpCas9	negative selection	7309058
66173645	66173668	X	-	27260156	HT29	viability	TTGTAGATATGGCTGCCCCCCGG	HEPH	ENSG00000089472	0.023946203588110615	[1040]	[1175,1536,1319,1135]	0	hSpCas9	negative selection	7309059
66173721	66173744	X	-	27260156	HT29	viability	TACATGAGAATGGTAGATCCAGG	HEPH	ENSG00000089472	0.1246556589281369	[1140]	[1581,1385,1531,1529]	2	hSpCas9	negative selection	7309060
66172388	66172411	X	-	27260156	MHHES1	viability	TCTTGTAGGTTCCCCCTATCCGG	HEPH	ENSG00000089472	0.6656248130180855	[608]	[1214,1408,1050,773]	9	hSpCas9	negative selection	7366048
66172543	66172566	X	-	27260156	MHHES1	viability	GTGGATGGTATAGGGACGAGTGG	HEPH	ENSG00000089472	0.8358927322833245	[62]	[106,132,180,89]	9	hSpCas9	negative selection	7366049
66173649	66173672	X	+	27260156	MHHES1	viability	GGGGCAGCCATATCTACAACTGG	HEPH	ENSG00000089472	0.14229733501225028	[131]	[188,306,84,102]	2	hSpCas9	negative selection	7366050
66173747	66173770	X	+	27260156	MHHES1	viability	GCTCCACGAGACATTGCAACTGG	HEPH	ENSG00000089472	0.021374073864498522	[228]	[301,325,279,166]	0	hSpCas9	negative selection	7430309
66173645	66173668	X	-	27260156	MHHES1	viability	TTGTAGATATGGCTGCCCCCCGG	HEPH	ENSG00000089472	0.009174766987357419	[1040]	[1053,1348,1466,893]	0	hSpCas9	negative selection	7430310
66173721	66173744	X	-	27260156	MHHES1	viability	TACATGAGAATGGTAGATCCAGG	HEPH	ENSG00000089472	0.13405759717164623	[1140]	[1559,1418,1657,1071]	2	hSpCas9	negative selection	7430311
66172388	66172411	X	-	27260156	MEWO	viability	TCTTGTAGGTTCCCCCTATCCGG	HEPH	ENSG00000089472	0.45280965532695255	[608]	[647,937,726]	8	hSpCas9	negative selection	7487299
66172543	66172566	X	-	27260156	MEWO	viability	GTGGATGGTATAGGGACGAGTGG	HEPH	ENSG00000089472	0.47938340112139155	[62]	[78,57,108]	8	hSpCas9	negative selection	7487300
66173649	66173672	X	+	27260156	MEWO	viability	GGGGCAGCCATATCTACAACTGG	HEPH	ENSG00000089472	-0.017865385939878742	[131]	[162,89,120]	0	hSpCas9	negative selection	7487301
66173747	66173770	X	+	27260156	MEWO	viability	GCTCCACGAGACATTGCAACTGG	HEPH	ENSG00000089472	-0.5032384201541762	[228]	[92,183,164]	-8	hSpCas9	negative selection	7551560
66173645	66173668	X	-	27260156	MEWO	viability	TTGTAGATATGGCTGCCCCCCGG	HEPH	ENSG00000089472	0.1397482243725927	[1040]	[1398,839,1043]	3	hSpCas9	negative selection	7551561
66173721	66173744	X	-	27260156	MEWO	viability	TACATGAGAATGGTAGATCCAGG	HEPH	ENSG00000089472	-0.14616900868191052	[1140]	[1224,983,734]	-3	hSpCas9	negative selection	7551562
66172388	66172411	X	-	27260156	LNCAPCLONEFGC	viability	TCTTGTAGGTTCCCCCTATCCGG	HEPH	ENSG00000089472	0.5993039509908062	[608]	[591,907,953,905]	8	hSpCas9	negative selection	7608550
66172543	66172566	X	-	27260156	LNCAPCLONEFGC	viability	GTGGATGGTATAGGGACGAGTGG	HEPH	ENSG00000089472	0.3371717381086774	[62]	[88,45,46,103]	5	hSpCas9	negative selection	7608551
66173649	66173672	X	+	27260156	LNCAPCLONEFGC	viability	GGGGCAGCCATATCTACAACTGG	HEPH	ENSG00000089472	0.31135299386216064	[131]	[113,140,238,113]	5	hSpCas9	negative selection	7608552
66173747	66173770	X	+	27260156	LNCAPCLONEFGC	viability	GCTCCACGAGACATTGCAACTGG	HEPH	ENSG00000089472	0.024998042049346747	[228]	[212,215,178,230]	0	hSpCas9	negative selection	7672811
66173645	66173668	X	-	27260156	LNCAPCLONEFGC	viability	TTGTAGATATGGCTGCCCCCCGG	HEPH	ENSG00000089472	0.18390241045671107	[1040]	[1036,792,1285,1218]	3	hSpCas9	negative selection	7672812
66173721	66173744	X	-	27260156	LNCAPCLONEFGC	viability	TACATGAGAATGGTAGATCCAGG	HEPH	ENSG00000089472	0.2102113812877311	[1140]	[1323,1115,1149,1187]	3	hSpCas9	negative selection	7672813
66172388	66172411	X	-	27260156	PANC0327	viability	TCTTGTAGGTTCCCCCTATCCGG	HEPH	ENSG00000089472	0.586013257718832	[608]	[1275,630,574,826]	8	hSpCas9	negative selection	7729801
66172543	66172566	X	-	27260156	PANC0327	viability	GTGGATGGTATAGGGACGAGTGG	HEPH	ENSG00000089472	1.3006037645955753	[62]	[174,94,158,130]	9	hSpCas9	negative selection	7729802
66173649	66173672	X	+	27260156	PANC0327	viability	GGGGCAGCCATATCTACAACTGG	HEPH	ENSG00000089472	0.28895551007276654	[131]	[442,30,74,62]	4	hSpCas9	negative selection	7729803
66173747	66173770	X	+	27260156	PANC0327	viability	GCTCCACGAGACATTGCAACTGG	HEPH	ENSG00000089472	-0.6349498379995744	[228]	[201,104,67,157]	-7	hSpCas9	negative selection	7794062
66173645	66173668	X	-	27260156	PANC0327	viability	TTGTAGATATGGCTGCCCCCCGG	HEPH	ENSG00000089472	0.191274642264605	[1040]	[687,1069,1142,1289]	3	hSpCas9	negative selection	7794063
66173721	66173744	X	-	27260156	PANC0327	viability	TACATGAGAATGGTAGATCCAGG	HEPH	ENSG00000089472	0.42321385194668526	[1140]	[1147,1140,1986,1171]	6	hSpCas9	negative selection	7794064
66172388	66172411	X	-	27260156	NCIH2009	viability	TCTTGTAGGTTCCCCCTATCCGG	HEPH	ENSG00000089472	0.9326845743088483	[608]	[1994,1514,1434]	9	hSpCas9	negative selection	7851052
66172543	66172566	X	-	27260156	NCIH2009	viability	GTGGATGGTATAGGGACGAGTGG	HEPH	ENSG00000089472	0.8308828924950986	[62]	[90,127,237]	9	hSpCas9	negative selection	7851053
66173649	66173672	X	+	27260156	NCIH2009	viability	GGGGCAGCCATATCTACAACTGG	HEPH	ENSG00000089472	0.6375763960573426	[131]	[196,202,443]	8	hSpCas9	negative selection	7851054
66173747	66173770	X	+	27260156	NCIH2009	viability	GCTCCACGAGACATTGCAACTGG	HEPH	ENSG00000089472	0.11178103757394253	[228]	[250,227,540]	1	hSpCas9	negative selection	7915313
66173645	66173668	X	-	27260156	NCIH2009	viability	TTGTAGATATGGCTGCCCCCCGG	HEPH	ENSG00000089472	0.023864303857010105	[1040]	[1573,1501,1375]	0	hSpCas9	negative selection	7915314
66173721	66173744	X	-	27260156	NCIH2009	viability	TACATGAGAATGGTAGATCCAGG	HEPH	ENSG00000089472	0.08096038390471794	[1140]	[2059,1495,1576]	1	hSpCas9	negative selection	7915315
66172388	66172411	X	-	27260156	NCIH1373	viability	TCTTGTAGGTTCCCCCTATCCGG	HEPH	ENSG00000089472	0.8059717688392096	[608]	[1176,1026,994,423]	7	hSpCas9	negative selection	7972303
66172543	66172566	X	-	27260156	NCIH1373	viability	GTGGATGGTATAGGGACGAGTGG	HEPH	ENSG00000089472	1.1238445489573543	[62]	[32,163,169,60]	9	hSpCas9	negative selection	7972304
66173649	66173672	X	+	27260156	NCIH1373	viability	GGGGCAGCCATATCTACAACTGG	HEPH	ENSG00000089472	0.04255640030107655	[131]	[298,64,72,54]	0	hSpCas9	negative selection	7972305
66173747	66173770	X	+	27260156	NCIH1373	viability	GCTCCACGAGACATTGCAACTGG	HEPH	ENSG00000089472	0.5964328969142814	[228]	[290,222,284,204]	6	hSpCas9	negative selection	8036564
66173645	66173668	X	-	27260156	NCIH1373	viability	TTGTAGATATGGCTGCCCCCCGG	HEPH	ENSG00000089472	-0.2064397722108957	[1040]	[1197,748,1131,266]	-2	hSpCas9	negative selection	8036565
66173721	66173744	X	-	27260156	NCIH1373	viability	TACATGAGAATGGTAGATCCAGG	HEPH	ENSG00000089472	0.6760822264750066	[1140]	[2029,3347,902,457]	6	hSpCas9	negative selection	8036566
66172388	66172411	X	-	27260156	PATU8902	viability	TCTTGTAGGTTCCCCCTATCCGG	HEPH	ENSG00000089472	0.6834953704947082	[608]	[1339,1342,1236,1575]	7	hSpCas9	negative selection	8093554
66172543	66172566	X	-	27260156	PATU8902	viability	GTGGATGGTATAGGGACGAGTGG	HEPH	ENSG00000089472	-1.0029158808186187	[62]	[4,31,6,153]	-7	hSpCas9	negative selection	8093555
66173649	66173672	X	+	27260156	PATU8902	viability	GGGGCAGCCATATCTACAACTGG	HEPH	ENSG00000089472	-0.16786707186683092	[131]	[173,160,160,156]	-2	hSpCas9	negative selection	8093556
66173747	66173770	X	+	27260156	PATU8902	viability	GCTCCACGAGACATTGCAACTGG	HEPH	ENSG00000089472	0.540606615763249	[228]	[433,584,291,602]	5	hSpCas9	negative selection	8157815
66173645	66173668	X	-	27260156	PATU8902	viability	TTGTAGATATGGCTGCCCCCCGG	HEPH	ENSG00000089472	0.004176193171254061	[1040]	[1411,1958,934,1659]	0	hSpCas9	negative selection	8157816
66173721	66173744	X	-	27260156	PATU8902	viability	TACATGAGAATGGTAGATCCAGG	HEPH	ENSG00000089472	0.0780739091630478	[1140]	[2224,1488,1235,1876]	0	hSpCas9	negative selection	8157817
66172388	66172411	X	-	27260156	PANC1	viability	TCTTGTAGGTTCCCCCTATCCGG	HEPH	ENSG00000089472	0.7218575210732754	[608]	[910,1153,798,663]	9	hSpCas9	negative selection	8214805
66172543	66172566	X	-	27260156	PANC1	viability	GTGGATGGTATAGGGACGAGTGG	HEPH	ENSG00000089472	0.7920741354269438	[62]	[95,85,91,96]	9	hSpCas9	negative selection	8214806
66173649	66173672	X	+	27260156	PANC1	viability	GGGGCAGCCATATCTACAACTGG	HEPH	ENSG00000089472	0.1785165287476569	[131]	[113,183,151,80]	3	hSpCas9	negative selection	8214807
66173747	66173770	X	+	27260156	PANC1	viability	GCTCCACGAGACATTGCAACTGG	HEPH	ENSG00000089472	-0.319273229316402	[228]	[151,207,119,157]	-5	hSpCas9	negative selection	8279066
66173645	66173668	X	-	27260156	PANC1	viability	TTGTAGATATGGCTGCCCCCCGG	HEPH	ENSG00000089472	0.17196195812400328	[1040]	[1048,1273,747,994]	2	hSpCas9	negative selection	8279067
66173721	66173744	X	-	27260156	PANC1	viability	TACATGAGAATGGTAGATCCAGG	HEPH	ENSG00000089472	-0.09641251482769264	[1140]	[879,1343,826,720]	-1	hSpCas9	negative selection	8279068
66172388	66172411	X	-	27260156	PANC0813	viability	TCTTGTAGGTTCCCCCTATCCGG	HEPH	ENSG00000089472	0.5670391645808361	[608]	[1274,1094,909,980]	8	hSpCas9	negative selection	8336056
66172543	66172566	X	-	27260156	PANC0813	viability	GTGGATGGTATAGGGACGAGTGG	HEPH	ENSG00000089472	1.2518019176743513	[62]	[224,204,243,42]	9	hSpCas9	negative selection	8336057
66173649	66173672	X	+	27260156	PANC0813	viability	GGGGCAGCCATATCTACAACTGG	HEPH	ENSG00000089472	0.5516596329383157	[131]	[130,142,438,189]	8	hSpCas9	negative selection	8336058
66173747	66173770	X	+	27260156	PANC0813	viability	GCTCCACGAGACATTGCAACTGG	HEPH	ENSG00000089472	-0.036522355283942876	[228]	[303,266,196,282]	0	hSpCas9	negative selection	8400317
66173645	66173668	X	-	27260156	PANC0813	viability	TTGTAGATATGGCTGCCCCCCGG	HEPH	ENSG00000089472	0.0366277347992765	[1040]	[1322,1266,1281,1154]	0	hSpCas9	negative selection	8400318
66173721	66173744	X	-	27260156	PANC0813	viability	TACATGAGAATGGTAGATCCAGG	HEPH	ENSG00000089472	0.13139844907451814	[1140]	[1614,1573,1513,1195]	2	hSpCas9	negative selection	8400319
66172388	66172411	X	-	27260156	RDES	viability	TCTTGTAGGTTCCCCCTATCCGG	HEPH	ENSG00000089472	0.759393215350322	[608]	[1075,1144,1164,1372]	9	hSpCas9	negative selection	8457307
66172543	66172566	X	-	27260156	RDES	viability	GTGGATGGTATAGGGACGAGTGG	HEPH	ENSG00000089472	0.3840960655744472	[62]	[93,77,127,74]	6	hSpCas9	negative selection	8457308
66173649	66173672	X	+	27260156	RDES	viability	GGGGCAGCCATATCTACAACTGG	HEPH	ENSG00000089472	0.2949888661721696	[131]	[149,228,215,141]	5	hSpCas9	negative selection	8457309
66173747	66173770	X	+	27260156	RDES	viability	GCTCCACGAGACATTGCAACTGG	HEPH	ENSG00000089472	0.1330953171328344	[228]	[203,290,265,423]	2	hSpCas9	negative selection	8521568
66173645	66173668	X	-	27260156	RDES	viability	TTGTAGATATGGCTGCCCCCCGG	HEPH	ENSG00000089472	-0.09097298865181114	[1040]	[952,1128,1161,1277]	-1	hSpCas9	negative selection	8521569
66173721	66173744	X	-	27260156	RDES	viability	TACATGAGAATGGTAGATCCAGG	HEPH	ENSG00000089472	0.18079371484962592	[1140]	[1252,1403,1389,1987]	3	hSpCas9	negative selection	8521570
66172388	66172411	X	-	27260156	PC3	viability	TCTTGTAGGTTCCCCCTATCCGG	HEPH	ENSG00000089472	0.17722845211190014	[608]	[397,605,1247,785]	4	hSpCas9	negative selection	8578558
66172543	66172566	X	-	27260156	PC3	viability	GTGGATGGTATAGGGACGAGTGG	HEPH	ENSG00000089472	0.34444014468991524	[62]	[71,57,60,115]	7	hSpCas9	negative selection	8578559
66173649	66173672	X	+	27260156	PC3	viability	GGGGCAGCCATATCTACAACTGG	HEPH	ENSG00000089472	-0.09426729330399519	[131]	[53,144,210,137]	-2	hSpCas9	negative selection	8578560
66173747	66173770	X	+	27260156	PC3	viability	GCTCCACGAGACATTGCAACTGG	HEPH	ENSG00000089472	-0.16742290530029003	[228]	[80,186,284,338]	-4	hSpCas9	negative selection	8642819
66173645	66173668	X	-	27260156	PC3	viability	TTGTAGATATGGCTGCCCCCCGG	HEPH	ENSG00000089472	0.039705122295605744	[1040]	[728,973,1770,1109]	0	hSpCas9	negative selection	8642820
66173721	66173744	X	-	27260156	PC3	viability	TACATGAGAATGGTAGATCCAGG	HEPH	ENSG00000089472	0.02033848486273082	[1140]	[681,1305,1772,1184]	0	hSpCas9	negative selection	8642821
66172388	66172411	X	-	27260156	PATU8988T	viability	TCTTGTAGGTTCCCCCTATCCGG	HEPH	ENSG00000089472	0.3549709548260635	[608]	[959,905,591,552]	6	hSpCas9	negative selection	8699809
66172543	66172566	X	-	27260156	PATU8988T	viability	GTGGATGGTATAGGGACGAGTGG	HEPH	ENSG00000089472	1.0075213862506738	[62]	[206,80,78,118]	9	hSpCas9	negative selection	8699810
66173649	66173672	X	+	27260156	PATU8988T	viability	GGGGCAGCCATATCTACAACTGG	HEPH	ENSG00000089472	0.71152041589994	[131]	[229,259,133,217]	9	hSpCas9	negative selection	8699811
66173747	66173770	X	+	27260156	PATU8988T	viability	GCTCCACGAGACATTGCAACTGG	HEPH	ENSG00000089472	0.10010847661718647	[228]	[158,216,375,188]	1	hSpCas9	negative selection	8764070
66173645	66173668	X	-	27260156	PATU8988T	viability	TTGTAGATATGGCTGCCCCCCGG	HEPH	ENSG00000089472	0.1578582658880403	[1040]	[1217,1315,908,1061]	2	hSpCas9	negative selection	8764071
66173721	66173744	X	-	27260156	PATU8988T	viability	TACATGAGAATGGTAGATCCAGG	HEPH	ENSG00000089472	0.02936108394585757	[1140]	[986,979,1296,1228]	0	hSpCas9	negative selection	8764072
66172388	66172411	X	-	27260156	T47D	viability	TCTTGTAGGTTCCCCCTATCCGG	HEPH	ENSG00000089472	0.46380957033368414	[608]	[959,791,1142,1033]	8	hSpCas9	negative selection	8821060
66172543	66172566	X	-	27260156	T47D	viability	GTGGATGGTATAGGGACGAGTGG	HEPH	ENSG00000089472	0.5073761455317798	[62]	[104,81,83,149]	9	hSpCas9	negative selection	8821061
66173649	66173672	X	+	27260156	T47D	viability	GGGGCAGCCATATCTACAACTGG	HEPH	ENSG00000089472	0.21676726894615728	[131]	[133,188,214,174]	4	hSpCas9	negative selection	8821062
66173747	66173770	X	+	27260156	T47D	viability	GCTCCACGAGACATTGCAACTGG	HEPH	ENSG00000089472	-0.030241242031741944	[228]	[252,224,252,318]	0	hSpCas9	negative selection	8885321
66173645	66173668	X	-	27260156	T47D	viability	TTGTAGATATGGCTGCCCCCCGG	HEPH	ENSG00000089472	0.03165311947860716	[1040]	[1242,1290,1193,1225]	0	hSpCas9	negative selection	8885322
66173721	66173744	X	-	27260156	T47D	viability	TACATGAGAATGGTAGATCCAGG	HEPH	ENSG00000089472	0.06396673471693637	[1140]	[1322,1318,1452,1469]	1	hSpCas9	negative selection	8885323
66172388	66172411	X	-	27260156	SU8686	viability	TCTTGTAGGTTCCCCCTATCCGG	HEPH	ENSG00000089472	0.5598675788507086	[608]	[864,761,1003,955]	8	hSpCas9	negative selection	8942311
66172543	66172566	X	-	27260156	SU8686	viability	GTGGATGGTATAGGGACGAGTGG	HEPH	ENSG00000089472	1.104061409783554	[62]	[150,88,128,177]	9	hSpCas9	negative selection	8942312
66173649	66173672	X	+	27260156	SU8686	viability	GGGGCAGCCATATCTACAACTGG	HEPH	ENSG00000089472	-0.13859829532260193	[131]	[109,114,135,114]	-2	hSpCas9	negative selection	8942313
66173747	66173770	X	+	27260156	SU8686	viability	GCTCCACGAGACATTGCAACTGG	HEPH	ENSG00000089472	-0.0314007188012666	[228]	[145,170,381,204]	0	hSpCas9	negative selection	9006572
66173645	66173668	X	-	27260156	SU8686	viability	TTGTAGATATGGCTGCCCCCCGG	HEPH	ENSG00000089472	-0.03372698127562557	[1040]	[1009,883,1043,1122]	0	hSpCas9	negative selection	9006573
66173721	66173744	X	-	27260156	SU8686	viability	TACATGAGAATGGTAGATCCAGG	HEPH	ENSG00000089472	0.15069321907371402	[1140]	[1027,925,1240,2009]	2	hSpCas9	negative selection	9006574
66172388	66172411	X	-	27260156	SKES1	viability	TCTTGTAGGTTCCCCCTATCCGG	HEPH	ENSG00000089472	0.48051537410837025	[608]	[1050,883,822,676]	8	hSpCas9	negative selection	9063562
66172543	66172566	X	-	27260156	SKES1	viability	GTGGATGGTATAGGGACGAGTGG	HEPH	ENSG00000089472	0.16848485477109065	[62]	[80,36,80,78]	3	hSpCas9	negative selection	9063563
66173649	66173672	X	+	27260156	SKES1	viability	GGGGCAGCCATATCTACAACTGG	HEPH	ENSG00000089472	-0.05671908721380947	[131]	[132,109,187,77]	-1	hSpCas9	negative selection	9063564
66173747	66173770	X	+	27260156	SKES1	viability	GCTCCACGAGACATTGCAACTGG	HEPH	ENSG00000089472	-0.09799522578956488	[228]	[188,285,247,141]	-2	hSpCas9	negative selection	9127823
66173645	66173668	X	-	27260156	SKES1	viability	TTGTAGATATGGCTGCCCCCCGG	HEPH	ENSG00000089472	-0.11864746415804861	[1040]	[1066,1016,910,855]	-3	hSpCas9	negative selection	9127824
66173721	66173744	X	-	27260156	SKES1	viability	TACATGAGAATGGTAGATCCAGG	HEPH	ENSG00000089472	0.059243385409107896	[1140]	[1490,1313,1178,845]	1	hSpCas9	negative selection	9127825
66172388	66172411	X	-	27260156	TOV112D	viability	TCTTGTAGGTTCCCCCTATCCGG	HEPH	ENSG00000089472	0.48489229041044773	[608]	[758,1398,771,615]	8	hSpCas9	negative selection	9184813
66172543	66172566	X	-	27260156	TOV112D	viability	GTGGATGGTATAGGGACGAGTGG	HEPH	ENSG00000089472	0.5437497199887154	[62]	[124,59,60,115]	8	hSpCas9	negative selection	9184814
66173649	66173672	X	+	27260156	TOV112D	viability	GGGGCAGCCATATCTACAACTGG	HEPH	ENSG00000089472	0.11137630690599631	[131]	[96,202,139,141]	2	hSpCas9	negative selection	9184815
66173747	66173770	X	+	27260156	TOV112D	viability	GCTCCACGAGACATTGCAACTGG	HEPH	ENSG00000089472	-0.08275663976720127	[228]	[182,332,240,136]	-1	hSpCas9	negative selection	9249074
66173645	66173668	X	-	27260156	TOV112D	viability	TTGTAGATATGGCTGCCCCCCGG	HEPH	ENSG00000089472	0.07024382946444474	[1040]	[1036,1325,1086,981]	1	hSpCas9	negative selection	9249075
66173721	66173744	X	-	27260156	TOV112D	viability	TACATGAGAATGGTAGATCCAGG	HEPH	ENSG00000089472	0.013679457374601078	[1140]	[1166,1306,1401,785]	0	hSpCas9	negative selection	9249076
66172388	66172411	X	-	27260156	TC71	viability	TCTTGTAGGTTCCCCCTATCCGG	HEPH	ENSG00000089472	0.39408683399472694	[608]	[946,734,792,962]	8	hSpCas9	negative selection	9306064
66172543	66172566	X	-	27260156	TC71	viability	GTGGATGGTATAGGGACGAGTGG	HEPH	ENSG00000089472	0.7282591095072921	[62]	[119,83,87,158]	9	hSpCas9	negative selection	9306065
66173649	66173672	X	+	27260156	TC71	viability	GGGGCAGCCATATCTACAACTGG	HEPH	ENSG00000089472	0.1997854133278918	[131]	[165,189,111,184]	5	hSpCas9	negative selection	9306066
66173747	66173770	X	+	27260156	TC71	viability	GCTCCACGAGACATTGCAACTGG	HEPH	ENSG00000089472	-0.15692804626779533	[228]	[252,240,203,179]	-4	hSpCas9	negative selection	9370325
66173645	66173668	X	-	27260156	TC71	viability	TTGTAGATATGGCTGCCCCCCGG	HEPH	ENSG00000089472	0.027670155607200098	[1040]	[1147,1086,1149,1165]	0	hSpCas9	negative selection	9370326
66173721	66173744	X	-	27260156	TC71	viability	TACATGAGAATGGTAGATCCAGG	HEPH	ENSG00000089472	-0.052047313938158535	[1140]	[1068,1124,1242,1288]	-1	hSpCas9	negative selection	9370327
66172388	66172411	X	-	27260156	TC32	viability	TCTTGTAGGTTCCCCCTATCCGG	HEPH	ENSG00000089472	0.5512085650428766	[608]	[826,666,903,990]	8	hSpCas9	negative selection	9427315
66172543	66172566	X	-	27260156	TC32	viability	GTGGATGGTATAGGGACGAGTGG	HEPH	ENSG00000089472	0.46559656451773623	[62]	[62,79,89,93]	7	hSpCas9	negative selection	9427316
66173649	66173672	X	+	27260156	TC32	viability	GGGGCAGCCATATCTACAACTGG	HEPH	ENSG00000089472	0.07344540254770382	[131]	[102,98,186,151]	1	hSpCas9	negative selection	9427317
66173747	66173770	X	+	27260156	TC32	viability	GCTCCACGAGACATTGCAACTGG	HEPH	ENSG00000089472	-0.04561026305237004	[228]	[184,175,256,227]	-1	hSpCas9	negative selection	9491576
66173645	66173668	X	-	27260156	TC32	viability	TTGTAGATATGGCTGCCCCCCGG	HEPH	ENSG00000089472	0.059850754736550105	[1040]	[935,887,1235,1054]	1	hSpCas9	negative selection	9491577
66173721	66173744	X	-	27260156	TC32	viability	TACATGAGAATGGTAGATCCAGG	HEPH	ENSG00000089472	0.17567408238281534	[1140]	[1089,1048,1446,1305]	3	hSpCas9	negative selection	9491578
66170641	66170664	X	-	27869803	HPAFII	viability after 27 days	GCCCAGGTAGTAGACTCGAGTGG	HEPH	ENSG00000089472	0.6548097437609474	[418]	[420,284,NaN]	5	hSpCas9	negative selection	9609336
66172568	66172591	X	+	27869803	HPAFII	viability after 27 days	TCATGGTGTCTTCTACGAGAAGG	HEPH	ENSG00000089472	0.49051664876686074	[223]	[267,79,NaN]	4	hSpCas9	negative selection	9609337
66173708	66173731	X	-	27869803	HPAFII	viability after 27 days	TAGATCCAGGTGAGGCACGCTGG	HEPH	ENSG00000089472	1.1073184105387943	[258]	[216,356,NaN]	8	hSpCas9	negative selection	9609338
66188378	66188401	X	-	27869803	HPAFII	viability after 27 days	CTACATCCTGGCGTTGAGGAGGG	HEPH	ENSG00000089472	0.3026003773214125	[323]	[130,275,NaN]	2	hSpCas9	negative selection	9609339
66189858	66189881	X	-	27869803	HPAFII	viability after 27 days	CATCTCAGCAGTCACAAAGGTGG	HEPH	ENSG00000089472	0.2675357980687346	[414]	[200,313,NaN]	2	hSpCas9	negative selection	9609340
66192233	66192256	X	+	27869803	HPAFII	viability after 27 days	TCAATGGGACTATGGCCCGATGG	HEPH	ENSG00000089472	0.14863394750385361	[111]	[55,72,NaN]	1	hSpCas9	negative selection	9609341
66170641	66170664	X	-	27869803	HPAFII	viability after 15 days	GCCCAGGTAGTAGACTCGAGTGG	HEPH	ENSG00000089472	0.20580173951110692	[418]	[765,365,NaN]	2	hSpCas9	negative selection	9691785
66172568	66172591	X	+	27869803	HPAFII	viability after 15 days	TCATGGTGTCTTCTACGAGAAGG	HEPH	ENSG00000089472	0.42522072263176836	[223]	[424,259,NaN]	5	hSpCas9	negative selection	9691786
66173708	66173731	X	-	27869803	HPAFII	viability after 15 days	TAGATCCAGGTGAGGCACGCTGG	HEPH	ENSG00000089472	0.3008288150418747	[258]	[435,284,NaN]	3	hSpCas9	negative selection	9691787
66188378	66188401	X	-	27869803	HPAFII	viability after 15 days	CTACATCCTGGCGTTGAGGAGGG	HEPH	ENSG00000089472	-0.03475575134620951	[323]	[416,291,NaN]	0	hSpCas9	negative selection	9691788
66189858	66189881	X	-	27869803	HPAFII	viability after 15 days	CATCTCAGCAGTCACAAAGGTGG	HEPH	ENSG00000089472	0.2279258189710811	[414]	[850,317,NaN]	2	hSpCas9	negative selection	9691789
66192233	66192256	X	+	27869803	HPAFII	viability after 15 days	TCAATGGGACTATGGCCCGATGG	HEPH	ENSG00000089472	0.6923626629092507	[111]	[286,136,NaN]	7	hSpCas9	negative selection	9691790
66170641	66170664	X	-	27869803	ASPC1	viability after 36 days	GCCCAGGTAGTAGACTCGAGTGG	HEPH	ENSG00000089472	-0.05366731120308893	[896]	[585,268,124]	0	hSpCas9	negative selection	9774234
66172568	66172591	X	+	27869803	ASPC1	viability after 36 days	TCATGGTGTCTTCTACGAGAAGG	HEPH	ENSG00000089472	0.07283592046313168	[576]	[186,158,268]	0	hSpCas9	negative selection	9774235
66173708	66173731	X	-	27869803	ASPC1	viability after 36 days	TAGATCCAGGTGAGGCACGCTGG	HEPH	ENSG00000089472	0.7230634471795861	[801]	[313,547,492]	7	hSpCas9	negative selection	9774236
66188378	66188401	X	-	27869803	ASPC1	viability after 36 days	CTACATCCTGGCGTTGAGGAGGG	HEPH	ENSG00000089472	-1.062343318476621	[948]	[106,241,126]	-7	hSpCas9	negative selection	9774237
66189858	66189881	X	-	27869803	ASPC1	viability after 36 days	CATCTCAGCAGTCACAAAGGTGG	HEPH	ENSG00000089472	0.31882665879627625	[953]	[639,459,217]	3	hSpCas9	negative selection	9774238
66192233	66192256	X	+	27869803	ASPC1	viability after 36 days	TCAATGGGACTATGGCCCGATGG	HEPH	ENSG00000089472	0.3482300850686004	[469]	[73,314,216]	3	hSpCas9	negative selection	9774239
66170641	66170664	X	-	27869803	PATU8988S	viability after 35 days	GCCCAGGTAGTAGACTCGAGTGG	HEPH	ENSG00000089472	0.8695127137071043	[911]	[709,631,NaN]	8	hSpCas9	negative selection	9856683
66172568	66172591	X	+	27869803	PATU8988S	viability after 35 days	TCATGGTGTCTTCTACGAGAAGG	HEPH	ENSG00000089472	0.10240718706442753	[504]	[152,283,NaN]	1	hSpCas9	negative selection	9856684
66173708	66173731	X	-	27869803	PATU8988S	viability after 35 days	TAGATCCAGGTGAGGCACGCTGG	HEPH	ENSG00000089472	0.14055232776407725	[616]	[240,306,NaN]	1	hSpCas9	negative selection	9856685
66188378	66188401	X	-	27869803	PATU8988S	viability after 35 days	CTACATCCTGGCGTTGAGGAGGG	HEPH	ENSG00000089472	0.023892339060861745	[840]	[286,401,NaN]	0	hSpCas9	negative selection	9856686
66189858	66189881	X	-	27869803	PATU8988S	viability after 35 days	CATCTCAGCAGTCACAAAGGTGG	HEPH	ENSG00000089472	0.3904863853627776	[898]	[306,642,NaN]	4	hSpCas9	negative selection	9856687
66192233	66192256	X	+	27869803	PATU8988S	viability after 35 days	TCAATGGGACTATGGCCCGATGG	HEPH	ENSG00000089472	0.690209481137474	[290]	[234,142,NaN]	7	hSpCas9	negative selection	9856688
66170641	66170664	X	-	27869803	PATU8988S	viability after 31 days	GCCCAGGTAGTAGACTCGAGTGG	HEPH	ENSG00000089472	0.6635816901520423	[911]	[535,626,NaN]	7	hSpCas9	negative selection	9939132
66172568	66172591	X	+	27869803	PATU8988S	viability after 31 days	TCATGGTGTCTTCTACGAGAAGG	HEPH	ENSG00000089472	0.2340766719274835	[504]	[220,256,NaN]	3	hSpCas9	negative selection	9939133
66173708	66173731	X	-	27869803	PATU8988S	viability after 31 days	TAGATCCAGGTGAGGCACGCTGG	HEPH	ENSG00000089472	0.3290576084981991	[616]	[184,466,NaN]	4	hSpCas9	negative selection	9939134
66188378	66188401	X	-	27869803	PATU8988S	viability after 31 days	CTACATCCTGGCGTTGAGGAGGG	HEPH	ENSG00000089472	0.14603627241274797	[840]	[301,458,NaN]	1	hSpCas9	negative selection	9939135
66189858	66189881	X	-	27869803	PATU8988S	viability after 31 days	CATCTCAGCAGTCACAAAGGTGG	HEPH	ENSG00000089472	0.5206080125248023	[898]	[354,716,NaN]	6	hSpCas9	negative selection	9939136
66192233	66192256	X	+	27869803	PATU8988S	viability after 31 days	TCAATGGGACTATGGCCCGATGG	HEPH	ENSG00000089472	0.6739278933722298	[290]	[196,169,NaN]	7	hSpCas9	negative selection	9939137
66170641	66170664	X	-	27869803	HPAFII	viability after 35 days	GCCCAGGTAGTAGACTCGAGTGG	HEPH	ENSG00000089472	0.7473358715512312	[418]	[396,309,NaN]	5	hSpCas9	negative selection	10021581
66172568	66172591	X	+	27869803	HPAFII	viability after 35 days	TCATGGTGTCTTCTACGAGAAGG	HEPH	ENSG00000089472	1.2332708789677531	[223]	[410,103,NaN]	8	hSpCas9	negative selection	10021582
66173708	66173731	X	-	27869803	HPAFII	viability after 35 days	TAGATCCAGGTGAGGCACGCTGG	HEPH	ENSG00000089472	1.3958650393671932	[258]	[170,540,NaN]	8	hSpCas9	negative selection	10021583
66188378	66188401	X	-	27869803	HPAFII	viability after 35 days	CTACATCCTGGCGTTGAGGAGGG	HEPH	ENSG00000089472	-0.0808279054781505	[323]	[92,224,NaN]	0	hSpCas9	negative selection	10021584
66189858	66189881	X	-	27869803	HPAFII	viability after 35 days	CATCTCAGCAGTCACAAAGGTGG	HEPH	ENSG00000089472	0.3499117096407188	[414]	[136,414,NaN]	2	hSpCas9	negative selection	10021585
66192233	66192256	X	+	27869803	HPAFII	viability after 35 days	TCAATGGGACTATGGCCCGATGG	HEPH	ENSG00000089472	-0.050453271558010826	[111]	[26,85,NaN]	0	hSpCas9	negative selection	10021586
66170641	66170664	X	-	27869803	HPAFII	viability after 31 days	GCCCAGGTAGTAGACTCGAGTGG	HEPH	ENSG00000089472	0.5213389908193796	[418]	[426,239,NaN]	4	hSpCas9	negative selection	10104030
66172568	66172591	X	+	27869803	HPAFII	viability after 31 days	TCATGGTGTCTTCTACGAGAAGG	HEPH	ENSG00000089472	1.256928790764742	[223]	[432,155,NaN]	8	hSpCas9	negative selection	10104031
66173708	66173731	X	-	27869803	HPAFII	viability after 31 days	TAGATCCAGGTGAGGCACGCTGG	HEPH	ENSG00000089472	0.9253860324758142	[258]	[120,444,NaN]	7	hSpCas9	negative selection	10104032
66188378	66188401	X	-	27869803	HPAFII	viability after 31 days	CTACATCCTGGCGTTGAGGAGGG	HEPH	ENSG00000089472	0.7648508209276659	[323]	[151,479,NaN]	5	hSpCas9	negative selection	10104033
66189858	66189881	X	-	27869803	HPAFII	viability after 31 days	CATCTCAGCAGTCACAAAGGTGG	HEPH	ENSG00000089472	0.2617802411619796	[414]	[172,394,NaN]	1	hSpCas9	negative selection	10104034
66192233	66192256	X	+	27869803	HPAFII	viability after 31 days	TCAATGGGACTATGGCCCGATGG	HEPH	ENSG00000089472	-0.2530799016815384	[111]	[46,58,NaN]	-2	hSpCas9	negative selection	10104035
66197693	66197716	X	-	28162770	P31FUJ	viability	AGGGCTTGGCAACCAAGCCAGGG	HEPH	ENSG00000089472	0.9047013193355564	[89]	[197]	9	hSpCas9	negative selection	10168333
66260108	66260131	X	+	28162770	P31FUJ	viability	GAACTACCGGGCAGATGTGGTGG	HEPH	ENSG00000089472	0.38610762823011546	[55]	[85]	4	hSpCas9	negative selection	10168334
66189803	66189826	X	+	28162770	P31FUJ	viability	GGACAGATGCTGACTACCCGTGG	HEPH	ENSG00000089472	-0.16489813991257524	[248]	[260]	-2	hSpCas9	negative selection	10168335
66195117	66195140	X	+	28162770	P31FUJ	viability	GGTGGGTGACACCATTCAGGTGG	HEPH	ENSG00000089472	0.6709824803263182	[154]	[289]	7	hSpCas9	negative selection	10168336
66197761	66197784	X	-	28162770	P31FUJ	viability	ACAAGCAGGATCCTGAGCAGTGG	HEPH	ENSG00000089472	0.8375871234770192	[199]	[419]	8	hSpCas9	negative selection	10168337
66197847	66197870	X	-	28162770	P31FUJ	viability	CCAGCCCTGCACACCAGCAGCGG	HEPH	ENSG00000089472	0.6442507354246546	[354]	[651]	7	hSpCas9	negative selection	10168338
66198865	66198888	X	+	28162770	P31FUJ	viability	ATTGGGCCTGCAGAAAGGGGTGG	HEPH	ENSG00000089472	0.33508678294783606	[169]	[251]	3	hSpCas9	negative selection	10168339
66200580	66200603	X	+	28162770	P31FUJ	viability	CATGTGCAAGGGTGACACAGTGG	HEPH	ENSG00000089472	0.7205868532940316	[172]	[334]	8	hSpCas9	negative selection	10168340
66207256	66207279	X	+	28162770	P31FUJ	viability	GTATTCAGGGAATACACTGATGG	HEPH	ENSG00000089472	0.4642528040658318	[754]	[1223]	5	hSpCas9	negative selection	10168341
66208176	66208199	X	-	28162770	P31FUJ	viability	GAGCATGCACAGAGTAGGGGCGG	HEPH	ENSG00000089472	0.2936818310410482	[192]	[277]	3	hSpCas9	negative selection	10168342
66197693	66197716	X	-	28162770	TF1	viability	AGGGCTTGGCAACCAAGCCAGGG	HEPH	ENSG00000089472	NaN	[NaN]	[116]	1	hSpCas9	negative selection	10337699
66260108	66260131	X	+	28162770	TF1	viability	GAACTACCGGGCAGATGTGGTGG	HEPH	ENSG00000089472	NaN	[NaN]	[39]	1	hSpCas9	negative selection	10337700
66189803	66189826	X	+	28162770	TF1	viability	GGACAGATGCTGACTACCCGTGG	HEPH	ENSG00000089472	NaN	[NaN]	[189]	1	hSpCas9	negative selection	10337701
66195117	66195140	X	+	28162770	TF1	viability	GGTGGGTGACACCATTCAGGTGG	HEPH	ENSG00000089472	NaN	[NaN]	[105]	1	hSpCas9	negative selection	10337702
66197761	66197784	X	-	28162770	TF1	viability	ACAAGCAGGATCCTGAGCAGTGG	HEPH	ENSG00000089472	NaN	[NaN]	[212]	1	hSpCas9	negative selection	10337703
66197847	66197870	X	-	28162770	TF1	viability	CCAGCCCTGCACACCAGCAGCGG	HEPH	ENSG00000089472	NaN	[NaN]	[603]	1	hSpCas9	negative selection	10337704
66198865	66198888	X	+	28162770	TF1	viability	ATTGGGCCTGCAGAAAGGGGTGG	HEPH	ENSG00000089472	NaN	[NaN]	[231]	1	hSpCas9	negative selection	10337705
66200580	66200603	X	+	28162770	TF1	viability	CATGTGCAAGGGTGACACAGTGG	HEPH	ENSG00000089472	NaN	[NaN]	[152]	1	hSpCas9	negative selection	10337706
66207256	66207279	X	+	28162770	TF1	viability	GTATTCAGGGAATACACTGATGG	HEPH	ENSG00000089472	NaN	[NaN]	[943]	1	hSpCas9	negative selection	10337707
66208176	66208199	X	-	28162770	TF1	viability	GAGCATGCACAGAGTAGGGGCGG	HEPH	ENSG00000089472	NaN	[NaN]	[409]	1	hSpCas9	negative selection	10337708
66197693	66197716	X	-	28162770	SKM1	viability	AGGGCTTGGCAACCAAGCCAGGG	HEPH	ENSG00000089472	0.262062566766469	[24]	[52]	2	hSpCas9	negative selection	10507065
66260108	66260131	X	+	28162770	SKM1	viability	GAACTACCGGGCAGATGTGGTGG	HEPH	ENSG00000089472	0.07846262842708018	[14]	[27]	0	hSpCas9	negative selection	10507066
66189803	66189826	X	+	28162770	SKM1	viability	GGACAGATGCTGACTACCCGTGG	HEPH	ENSG00000089472	0.7015602580350075	[47]	[137]	6	hSpCas9	negative selection	10507067
66195117	66195140	X	+	28162770	SKM1	viability	GGTGGGTGACACCATTCAGGTGG	HEPH	ENSG00000089472	-0.2205510745122806	[57]	[87]	-2	hSpCas9	negative selection	10507068
66197761	66197784	X	-	28162770	SKM1	viability	ACAAGCAGGATCCTGAGCAGTGG	HEPH	ENSG00000089472	0.20619519380864665	[75]	[154]	2	hSpCas9	negative selection	10507069
66197847	66197870	X	-	28162770	SKM1	viability	CCAGCCCTGCACACCAGCAGCGG	HEPH	ENSG00000089472	0.22380199159111935	[123]	[255]	2	hSpCas9	negative selection	10507070
66198865	66198888	X	+	28162770	SKM1	viability	ATTGGGCCTGCAGAAAGGGGTGG	HEPH	ENSG00000089472	0.07706939312721395	[36]	[68]	0	hSpCas9	negative selection	10507071
66200580	66200603	X	+	28162770	SKM1	viability	CATGTGCAAGGGTGACACAGTGG	HEPH	ENSG00000089472	1.5067800679064196	[41]	[210]	9	hSpCas9	negative selection	10507072
66207256	66207279	X	+	28162770	SKM1	viability	GTATTCAGGGAATACACTGATGG	HEPH	ENSG00000089472	0.4810224391404736	[168]	[416]	5	hSpCas9	negative selection	10507073
66208176	66208199	X	-	28162770	SKM1	viability	GAGCATGCACAGAGTAGGGGCGG	HEPH	ENSG00000089472	0.45810622117072974	[41]	[101]	4	hSpCas9	negative selection	10507074
66197693	66197716	X	-	28162770	SKM1	viability	AGGGCTTGGCAACCAAGCCAGGG	HEPH	ENSG00000089472	0.262062566766469	[24]	[52]	2	hSpCas9	negative selection	10676431
66260108	66260131	X	+	28162770	SKM1	viability	GAACTACCGGGCAGATGTGGTGG	HEPH	ENSG00000089472	0.07846262842708018	[14]	[27]	0	hSpCas9	negative selection	10676432
66189803	66189826	X	+	28162770	SKM1	viability	GGACAGATGCTGACTACCCGTGG	HEPH	ENSG00000089472	0.7015602580350075	[47]	[137]	6	hSpCas9	negative selection	10676433
66195117	66195140	X	+	28162770	SKM1	viability	GGTGGGTGACACCATTCAGGTGG	HEPH	ENSG00000089472	-0.2205510745122806	[57]	[87]	-2	hSpCas9	negative selection	10676434
66197761	66197784	X	-	28162770	SKM1	viability	ACAAGCAGGATCCTGAGCAGTGG	HEPH	ENSG00000089472	0.20619519380864665	[75]	[154]	2	hSpCas9	negative selection	10676435
66197847	66197870	X	-	28162770	SKM1	viability	CCAGCCCTGCACACCAGCAGCGG	HEPH	ENSG00000089472	0.22380199159111935	[123]	[255]	2	hSpCas9	negative selection	10676436
66198865	66198888	X	+	28162770	SKM1	viability	ATTGGGCCTGCAGAAAGGGGTGG	HEPH	ENSG00000089472	0.07706939312721395	[36]	[68]	0	hSpCas9	negative selection	10676437
66200580	66200603	X	+	28162770	SKM1	viability	CATGTGCAAGGGTGACACAGTGG	HEPH	ENSG00000089472	1.5067800679064196	[41]	[210]	9	hSpCas9	negative selection	10676438
66207256	66207279	X	+	28162770	SKM1	viability	GTATTCAGGGAATACACTGATGG	HEPH	ENSG00000089472	0.4810224391404736	[168]	[416]	5	hSpCas9	negative selection	10676439
66208176	66208199	X	-	28162770	SKM1	viability	GAGCATGCACAGAGTAGGGGCGG	HEPH	ENSG00000089472	0.45810622117072974	[41]	[101]	4	hSpCas9	negative selection	10676440
66197693	66197716	X	-	28162770	PL21	viability	AGGGCTTGGCAACCAAGCCAGGG	HEPH	ENSG00000089472	0.7941472548134832	[105]	[79]	6	hSpCas9	negative selection	10845797
66260108	66260131	X	+	28162770	PL21	viability	GAACTACCGGGCAGATGTGGTGG	HEPH	ENSG00000089472	0.6151771137681639	[29]	[19]	5	hSpCas9	negative selection	10845798
66189803	66189826	X	+	28162770	PL21	viability	GGACAGATGCTGACTACCCGTGG	HEPH	ENSG00000089472	0.025461083076373153	[227]	[100]	0	hSpCas9	negative selection	10845799
66195117	66195140	X	+	28162770	PL21	viability	GGTGGGTGACACCATTCAGGTGG	HEPH	ENSG00000089472	0.0608648258871923	[162]	[73]	0	hSpCas9	negative selection	10845800
66197761	66197784	X	-	28162770	PL21	viability	ACAAGCAGGATCCTGAGCAGTGG	HEPH	ENSG00000089472	0.02469760807944199	[261]	[115]	0	hSpCas9	negative selection	10845801
66197847	66197870	X	-	28162770	PL21	viability	CCAGCCCTGCACACCAGCAGCGG	HEPH	ENSG00000089472	0.48454767111568087	[334]	[203]	4	hSpCas9	negative selection	10845802
66198865	66198888	X	+	28162770	PL21	viability	ATTGGGCCTGCAGAAAGGGGTGG	HEPH	ENSG00000089472	0.09161515771115103	[137]	[63]	0	hSpCas9	negative selection	10845803
66200580	66200603	X	+	28162770	PL21	viability	CATGTGCAAGGGTGACACAGTGG	HEPH	ENSG00000089472	0.3163326319938429	[154]	[83]	3	hSpCas9	negative selection	10845804
66207256	66207279	X	+	28162770	PL21	viability	GTATTCAGGGAATACACTGATGG	HEPH	ENSG00000089472	0.5197575486894814	[499]	[311]	4	hSpCas9	negative selection	10845805
66208176	66208199	X	-	28162770	PL21	viability	GAGCATGCACAGAGTAGGGGCGG	HEPH	ENSG00000089472	0.11921961910575267	[164]	[77]	1	hSpCas9	negative selection	10845806
66197693	66197716	X	-	28162770	P31FUJ	viability	AGGGCTTGGCAACCAAGCCAGGG	HEPH	ENSG00000089472	0.9047013193355564	[89]	[197]	9	hSpCas9	negative selection	11015163
66260108	66260131	X	+	28162770	P31FUJ	viability	GAACTACCGGGCAGATGTGGTGG	HEPH	ENSG00000089472	0.38610762823011546	[55]	[85]	4	hSpCas9	negative selection	11015164
66189803	66189826	X	+	28162770	P31FUJ	viability	GGACAGATGCTGACTACCCGTGG	HEPH	ENSG00000089472	-0.16489813991257524	[248]	[260]	-2	hSpCas9	negative selection	11015165
66195117	66195140	X	+	28162770	P31FUJ	viability	GGTGGGTGACACCATTCAGGTGG	HEPH	ENSG00000089472	0.6709824803263182	[154]	[289]	7	hSpCas9	negative selection	11015166
66197761	66197784	X	-	28162770	P31FUJ	viability	ACAAGCAGGATCCTGAGCAGTGG	HEPH	ENSG00000089472	0.8375871234770192	[199]	[419]	8	hSpCas9	negative selection	11015167
66197847	66197870	X	-	28162770	P31FUJ	viability	CCAGCCCTGCACACCAGCAGCGG	HEPH	ENSG00000089472	0.6442507354246546	[354]	[651]	7	hSpCas9	negative selection	11015168
66198865	66198888	X	+	28162770	P31FUJ	viability	ATTGGGCCTGCAGAAAGGGGTGG	HEPH	ENSG00000089472	0.33508678294783606	[169]	[251]	3	hSpCas9	negative selection	11015169
66200580	66200603	X	+	28162770	P31FUJ	viability	CATGTGCAAGGGTGACACAGTGG	HEPH	ENSG00000089472	0.7205868532940316	[172]	[334]	8	hSpCas9	negative selection	11015170
66207256	66207279	X	+	28162770	P31FUJ	viability	GTATTCAGGGAATACACTGATGG	HEPH	ENSG00000089472	0.4642528040658318	[754]	[1223]	5	hSpCas9	negative selection	11015171
66208176	66208199	X	-	28162770	P31FUJ	viability	GAGCATGCACAGAGTAGGGGCGG	HEPH	ENSG00000089472	0.2936818310410482	[192]	[277]	3	hSpCas9	negative selection	11015172
66197693	66197716	X	-	28162770	OCIAML5	viability	AGGGCTTGGCAACCAAGCCAGGG	HEPH	ENSG00000089472	1.0563998796700607	[60]	[228]	8	hSpCas9	negative selection	11184529
66260108	66260131	X	+	28162770	OCIAML5	viability	GAACTACCGGGCAGATGTGGTGG	HEPH	ENSG00000089472	1.0146668982725386	[33]	[123]	8	hSpCas9	negative selection	11184530
66189803	66189826	X	+	28162770	OCIAML5	viability	GGACAGATGCTGACTACCCGTGG	HEPH	ENSG00000089472	-0.16213451054129832	[105]	[170]	-1	hSpCas9	negative selection	11184531
66195117	66195140	X	+	28162770	OCIAML5	viability	GGTGGGTGACACCATTCAGGTGG	HEPH	ENSG00000089472	0.9522983085877954	[68]	[240]	8	hSpCas9	negative selection	11184532
66197761	66197784	X	-	28162770	OCIAML5	viability	ACAAGCAGGATCCTGAGCAGTGG	HEPH	ENSG00000089472	-0.8453719182899888	[214]	[215]	-5	hSpCas9	negative selection	11184533
66197847	66197870	X	-	28162770	OCIAML5	viability	CCAGCCCTGCACACCAGCAGCGG	HEPH	ENSG00000089472	0.5181570810641467	[187]	[485]	4	hSpCas9	negative selection	11184534
66198865	66198888	X	+	28162770	OCIAML5	viability	ATTGGGCCTGCAGAAAGGGGTGG	HEPH	ENSG00000089472	-0.2479952471951362	[99]	[151]	-2	hSpCas9	negative selection	11184535
66200580	66200603	X	+	28162770	OCIAML5	viability	CATGTGCAAGGGTGACACAGTGG	HEPH	ENSG00000089472	1.0311197641532532	[89]	[331]	8	hSpCas9	negative selection	11184536
66207256	66207279	X	+	28162770	OCIAML5	viability	GTATTCAGGGAATACACTGATGG	HEPH	ENSG00000089472	0.8806834151891993	[376]	[1252]	7	hSpCas9	negative selection	11184537
66208176	66208199	X	-	28162770	OCIAML5	viability	GAGCATGCACAGAGTAGGGGCGG	HEPH	ENSG00000089472	1.4487227569652148	[54]	[270]	9	hSpCas9	negative selection	11184538
66197693	66197716	X	-	28162770	EOL1	viability	AGGGCTTGGCAACCAAGCCAGGG	HEPH	ENSG00000089472	-0.5802443804666382	[209]	[73]	-4	hSpCas9	negative selection	11353895
66260108	66260131	X	+	28162770	EOL1	viability	GAACTACCGGGCAGATGTGGTGG	HEPH	ENSG00000089472	-0.03481024393211918	[69]	[35]	0	hSpCas9	negative selection	11353896
66189803	66189826	X	+	28162770	EOL1	viability	GGACAGATGCTGACTACCCGTGG	HEPH	ENSG00000089472	0.040926955284863065	[368]	[199]	0	hSpCas9	negative selection	11353897
66195117	66195140	X	+	28162770	EOL1	viability	GGTGGGTGACACCATTCAGGTGG	HEPH	ENSG00000089472	0.393524077960182	[314]	[217]	3	hSpCas9	negative selection	11353898
66197761	66197784	X	-	28162770	EOL1	viability	ACAAGCAGGATCCTGAGCAGTGG	HEPH	ENSG00000089472	0.15424499353021576	[393]	[230]	1	hSpCas9	negative selection	11353899
66197847	66197870	X	-	28162770	EOL1	viability	CCAGCCCTGCACACCAGCAGCGG	HEPH	ENSG00000089472	-0.1118756366793392	[721]	[351]	-1	hSpCas9	negative selection	11353900
66198865	66198888	X	+	28162770	EOL1	viability	ATTGGGCCTGCAGAAAGGGGTGG	HEPH	ENSG00000089472	0.7065471193512445	[163]	[140]	6	hSpCas9	negative selection	11353901
66200580	66200603	X	+	28162770	EOL1	viability	CATGTGCAAGGGTGACACAGTGG	HEPH	ENSG00000089472	0.3479005390613819	[172]	[115]	3	hSpCas9	negative selection	11353902
66207256	66207279	X	+	28162770	EOL1	viability	GTATTCAGGGAATACACTGATGG	HEPH	ENSG00000089472	-0.16792650402315257	[756]	[354]	-1	hSpCas9	negative selection	11353903
66208176	66208199	X	-	28162770	EOL1	viability	GAGCATGCACAGAGTAGGGGCGG	HEPH	ENSG00000089472	2.838694183181852	[237]	[896]	9	hSpCas9	negative selection	11353904
66197693	66197716	X	-	28162770	MOLM13	viability	AGGGCTTGGCAACCAAGCCAGGG	HEPH	ENSG00000089472	1.7749987617203962	[136]	[338]	9	hSpCas9	negative selection	11523261
66260108	66260131	X	+	28162770	MOLM13	viability	GAACTACCGGGCAGATGTGGTGG	HEPH	ENSG00000089472	-0.6864387648467152	[68]	[30]	-4	hSpCas9	negative selection	11523262
66189803	66189826	X	+	28162770	MOLM13	viability	GGACAGATGCTGACTACCCGTGG	HEPH	ENSG00000089472	0.48071342190216243	[223]	[225]	3	hSpCas9	negative selection	11523263
66195117	66195140	X	+	28162770	MOLM13	viability	GGTGGGTGACACCATTCAGGTGG	HEPH	ENSG00000089472	-0.13270377089034163	[231]	[152]	-1	hSpCas9	negative selection	11523264
66197761	66197784	X	-	28162770	MOLM13	viability	ACAAGCAGGATCCTGAGCAGTGG	HEPH	ENSG00000089472	0.20861689450698406	[382]	[319]	1	hSpCas9	negative selection	11523265
66197847	66197870	X	-	28162770	MOLM13	viability	CCAGCCCTGCACACCAGCAGCGG	HEPH	ENSG00000089472	1.5142150045455072	[474]	[980]	9	hSpCas9	negative selection	11523266
66198865	66198888	X	+	28162770	MOLM13	viability	ATTGGGCCTGCAGAAAGGGGTGG	HEPH	ENSG00000089472	-0.12665916800577537	[150]	[99]	-1	hSpCas9	negative selection	11523267
66200580	66200603	X	+	28162770	MOLM13	viability	CATGTGCAAGGGTGACACAGTGG	HEPH	ENSG00000089472	0.07055388399919377	[215]	[163]	0	hSpCas9	negative selection	11523268
66207256	66207279	X	+	28162770	MOLM13	viability	GTATTCAGGGAATACACTGATGG	HEPH	ENSG00000089472	0.5670883308458872	[856]	[917]	4	hSpCas9	negative selection	11523269
66208176	66208199	X	-	28162770	MOLM13	viability	GAGCATGCACAGAGTAGGGGCGG	HEPH	ENSG00000089472	-0.439598479665883	[301]	[160]	-3	hSpCas9	negative selection	11523270
66197693	66197716	X	-	28162770	HEL	viability	AGGGCTTGGCAACCAAGCCAGGG	HEPH	ENSG00000089472	1.2675273132147014	[130]	[201]	9	hSpCas9	negative selection	11692627
66260108	66260131	X	+	28162770	HEL	viability	GAACTACCGGGCAGATGTGGTGG	HEPH	ENSG00000089472	-2.7357727912533725	[51]	[4]	-8	hSpCas9	negative selection	11692628
66189803	66189826	X	+	28162770	HEL	viability	GGACAGATGCTGACTACCCGTGG	HEPH	ENSG00000089472	1.1015242266443683	[202]	[278]	8	hSpCas9	negative selection	11692629
66195117	66195140	X	+	28162770	HEL	viability	GGTGGGTGACACCATTCAGGTGG	HEPH	ENSG00000089472	0.34207935386664595	[201]	[163]	3	hSpCas9	negative selection	11692630
66197761	66197784	X	-	28162770	HEL	viability	ACAAGCAGGATCCTGAGCAGTGG	HEPH	ENSG00000089472	1.3140011791157333	[291]	[464]	9	hSpCas9	negative selection	11692631
66197847	66197870	X	-	28162770	HEL	viability	CCAGCCCTGCACACCAGCAGCGG	HEPH	ENSG00000089472	0.9945247750530626	[372]	[475]	8	hSpCas9	negative selection	11692632
66198865	66198888	X	+	28162770	HEL	viability	ATTGGGCCTGCAGAAAGGGGTGG	HEPH	ENSG00000089472	-0.5190122379962552	[131]	[58]	-4	hSpCas9	negative selection	11692633
66200580	66200603	X	+	28162770	HEL	viability	CATGTGCAAGGGTGACACAGTGG	HEPH	ENSG00000089472	0.05777633127920079	[134]	[89]	0	hSpCas9	negative selection	11692634
66207256	66207279	X	+	28162770	HEL	viability	GTATTCAGGGAATACACTGATGG	HEPH	ENSG00000089472	0.47997504371752275	[627]	[560]	4	hSpCas9	negative selection	11692635
66208176	66208199	X	-	28162770	HEL	viability	GAGCATGCACAGAGTAGGGGCGG	HEPH	ENSG00000089472	0.21966401365609475	[239]	[178]	1	hSpCas9	negative selection	11692636
66197693	66197716	X	-	28162770	MV411	viability	AGGGCTTGGCAACCAAGCCAGGG	HEPH	ENSG00000089472	-0.36841895788416457	[117]	[76]	-3	hSpCas9	negative selection	11861993
66260108	66260131	X	+	28162770	MV411	viability	GAACTACCGGGCAGATGTGGTGG	HEPH	ENSG00000089472	0.6855586631746606	[30]	[41]	6	hSpCas9	negative selection	11861994
66189803	66189826	X	+	28162770	MV411	viability	GGACAGATGCTGACTACCCGTGG	HEPH	ENSG00000089472	0.7829313752396317	[177]	[257]	7	hSpCas9	negative selection	11861995
66195117	66195140	X	+	28162770	MV411	viability	GGTGGGTGACACCATTCAGGTGG	HEPH	ENSG00000089472	0.4835049090162997	[179]	[211]	4	hSpCas9	negative selection	11861996
66197761	66197784	X	-	28162770	MV411	viability	ACAAGCAGGATCCTGAGCAGTGG	HEPH	ENSG00000089472	0.42867786545292197	[253]	[287]	4	hSpCas9	negative selection	11861997
66197847	66197870	X	-	28162770	MV411	viability	CCAGCCCTGCACACCAGCAGCGG	HEPH	ENSG00000089472	0.48104584268335104	[420]	[494]	4	hSpCas9	negative selection	11861998
66198865	66198888	X	+	28162770	MV411	viability	ATTGGGCCTGCAGAAAGGGGTGG	HEPH	ENSG00000089472	0.2474375507827754	[114]	[114]	2	hSpCas9	negative selection	11861999
66200580	66200603	X	+	28162770	MV411	viability	CATGTGCAAGGGTGACACAGTGG	HEPH	ENSG00000089472	0.4717548490437153	[106]	[124]	4	hSpCas9	negative selection	11862000
66207256	66207279	X	+	28162770	MV411	viability	GTATTCAGGGAATACACTGATGG	HEPH	ENSG00000089472	0.7131011231315871	[503]	[695]	6	hSpCas9	negative selection	11862001
66208176	66208199	X	-	28162770	MV411	viability	GAGCATGCACAGAGTAGGGGCGG	HEPH	ENSG00000089472	0.6160821445771679	[157]	[203]	5	hSpCas9	negative selection	11862002
66197693	66197716	X	-	28162770	MONOMAC1	viability	AGGGCTTGGCAACCAAGCCAGGG	HEPH	ENSG00000089472	0.5034028710815383	[63]	[103]	5	hSpCas9	negative selection	12031359
66260108	66260131	X	+	28162770	MONOMAC1	viability	GAACTACCGGGCAGATGTGGTGG	HEPH	ENSG00000089472	0.014467258134157834	[18]	[21]	0	hSpCas9	negative selection	12031360
66189803	66189826	X	+	28162770	MONOMAC1	viability	GGACAGATGCTGACTACCCGTGG	HEPH	ENSG00000089472	1.0353743301018854	[122]	[288]	8	hSpCas9	negative selection	12031361
66195117	66195140	X	+	28162770	MONOMAC1	viability	GGTGGGTGACACCATTCAGGTGG	HEPH	ENSG00000089472	-0.5935542583675997	[128]	[97]	-5	hSpCas9	negative selection	12031362
66197761	66197784	X	-	28162770	MONOMAC1	viability	ACAAGCAGGATCCTGAGCAGTGG	HEPH	ENSG00000089472	0.46639971168468747	[160]	[254]	4	hSpCas9	negative selection	12031363
66197847	66197870	X	-	28162770	MONOMAC1	viability	CCAGCCCTGCACACCAGCAGCGG	HEPH	ENSG00000089472	0.7389825270386245	[218]	[418]	7	hSpCas9	negative selection	12031364
66198865	66198888	X	+	28162770	MONOMAC1	viability	ATTGGGCCTGCAGAAAGGGGTGG	HEPH	ENSG00000089472	-0.2180984625873834	[68]	[67]	-2	hSpCas9	negative selection	12031365
66200580	66200603	X	+	28162770	MONOMAC1	viability	CATGTGCAAGGGTGACACAGTGG	HEPH	ENSG00000089472	-0.3080681594482976	[80]	[74]	-3	hSpCas9	negative selection	12031366
66207256	66207279	X	+	28162770	MONOMAC1	viability	GTATTCAGGGAATACACTGATGG	HEPH	ENSG00000089472	0.2889224381499076	[386]	[541]	3	hSpCas9	negative selection	12031367
66208176	66208199	X	-	28162770	MONOMAC1	viability	GAGCATGCACAGAGTAGGGGCGG	HEPH	ENSG00000089472	0.925253582743874	[129]	[282]	8	hSpCas9	negative selection	12031368
66197693	66197716	X	-	28162770	OCIAML2	viability	AGGGCTTGGCAACCAAGCCAGGG	HEPH	ENSG00000089472	1.9003928191733706	[12]	[268]	9	hSpCas9	negative selection	12200725
66260108	66260131	X	+	28162770	OCIAML2	viability	GAACTACCGGGCAGATGTGGTGG	HEPH	ENSG00000089472	0.5799962478278067	[6]	[57]	5	hSpCas9	negative selection	12200726
66189803	66189826	X	+	28162770	OCIAML2	viability	GGACAGATGCTGACTACCCGTGG	HEPH	ENSG00000089472	0.6337068345725744	[29]	[257]	6	hSpCas9	negative selection	12200727
66195117	66195140	X	+	28162770	OCIAML2	viability	GGTGGGTGACACCATTCAGGTGG	HEPH	ENSG00000089472	0.41689544549942614	[39]	[295]	4	hSpCas9	negative selection	12200728
66197761	66197784	X	-	28162770	OCIAML2	viability	ACAAGCAGGATCCTGAGCAGTGG	HEPH	ENSG00000089472	-0.2779847472997654	[55]	[255]	-2	hSpCas9	negative selection	12200729
66197847	66197870	X	-	28162770	OCIAML2	viability	CCAGCCCTGCACACCAGCAGCGG	HEPH	ENSG00000089472	0.6614737107651838	[72]	[639]	6	hSpCas9	negative selection	12200730
66198865	66198888	X	+	28162770	OCIAML2	viability	ATTGGGCCTGCAGAAAGGGGTGG	HEPH	ENSG00000089472	-0.6018743585204137	[22]	[83]	-4	hSpCas9	negative selection	12200731
66200580	66200603	X	+	28162770	OCIAML2	viability	CATGTGCAAGGGTGACACAGTGG	HEPH	ENSG00000089472	0.9647563194284852	[21]	[237]	8	hSpCas9	negative selection	12200732
66207256	66207279	X	+	28162770	OCIAML2	viability	GTATTCAGGGAATACACTGATGG	HEPH	ENSG00000089472	0.8255216347117789	[95]	[942]	7	hSpCas9	negative selection	12200733
66208176	66208199	X	-	28162770	OCIAML2	viability	GAGCATGCACAGAGTAGGGGCGG	HEPH	ENSG00000089472	0.19679483567096798	[33]	[215]	1	hSpCas9	negative selection	12200734
66197693	66197716	X	-	28162770	OCIAML3	viability	AGGGCTTGGCAACCAAGCCAGGG	HEPH	ENSG00000089472	0.6760815230435812	[33]	[163]	6	hSpCas9	negative selection	12370091
66260108	66260131	X	+	28162770	OCIAML3	viability	GAACTACCGGGCAGATGTGGTGG	HEPH	ENSG00000089472	-0.2985517567979916	[10]	[26]	-2	hSpCas9	negative selection	12370092
66189803	66189826	X	+	28162770	OCIAML3	viability	GGACAGATGCTGACTACCCGTGG	HEPH	ENSG00000089472	0.6418806234965078	[37]	[178]	6	hSpCas9	negative selection	12370093
66195117	66195140	X	+	28162770	OCIAML3	viability	GGTGGGTGACACCATTCAGGTGG	HEPH	ENSG00000089472	0.14295795384204313	[38]	[129]	1	hSpCas9	negative selection	12370094
66197761	66197784	X	-	28162770	OCIAML3	viability	ACAAGCAGGATCCTGAGCAGTGG	HEPH	ENSG00000089472	0.4656986058001047	[70]	[295]	4	hSpCas9	negative selection	12370095
66197847	66197870	X	-	28162770	OCIAML3	viability	CCAGCCCTGCACACCAGCAGCGG	HEPH	ENSG00000089472	0.4463244537110548	[96]	[398]	4	hSpCas9	negative selection	12370096
66198865	66198888	X	+	28162770	OCIAML3	viability	ATTGGGCCTGCAGAAAGGGGTGG	HEPH	ENSG00000089472	-0.08921548828699022	[36]	[104]	0	hSpCas9	negative selection	12370097
66200580	66200603	X	+	28162770	OCIAML3	viability	CATGTGCAAGGGTGACACAGTGG	HEPH	ENSG00000089472	0.44251823570095095	[38]	[159]	4	hSpCas9	negative selection	12370098
66207256	66207279	X	+	28162770	OCIAML3	viability	GTATTCAGGGAATACACTGATGG	HEPH	ENSG00000089472	1.2990771557593253	[153]	[1143]	9	hSpCas9	negative selection	12370099
66208176	66208199	X	-	28162770	OCIAML3	viability	GAGCATGCACAGAGTAGGGGCGG	HEPH	ENSG00000089472	0.38737668150849	[38]	[153]	3	hSpCas9	negative selection	12370100