Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 6345
• Symbol: srl
• Description: sarcalumenin

DataSource: http://genomecrispr.dkfz.de/#!/results/srl

Export (tab separated) Export to Excel

Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
4195752	4195775	16	+	26472758	Jiyoye	viability	GAGGACCGTGAACTCAGAGGTGG	SRL	ENSG00000185739	-1.4045579810623048	[164]	[46]	-7	hSpCas9	negative selection	156315
4195721	4195744	16	-	26472758	Jiyoye	viability	GCCTAAGCTGAAAACCATCGAGG	SRL	ENSG00000185739	0.8064455649264006	[68]	[90]	5	hSpCas9	negative selection	156316
4197817	4197840	16	+	26472758	Jiyoye	viability	GAGTATTTTCCAGCCCAAGGAGG	SRL	ENSG00000185739	0.6327350819210041	[194]	[227]	4	hSpCas9	negative selection	156317
4204626	4204649	16	-	26472758	Jiyoye	viability	GCTTCTCTCCACAGAAGAGACGG	SRL	ENSG00000185739	1.9921378822270295	[38]	[116]	8	hSpCas9	negative selection	156318
4204557	4204580	16	-	26472758	Jiyoye	viability	GAAGACCCTCATGCTGAATGAGG	SRL	ENSG00000185739	1.8783179826698677	[144]	[401]	8	hSpCas9	negative selection	156319
4197826	4197849	16	-	26472758	Jiyoye	viability	GATAAACTACCTCCTTGGGCTGG	SRL	ENSG00000185739	-0.4571695191365603	[141]	[77]	-3	hSpCas9	negative selection	156320
4242055	4242078	16	-	26472758	Jiyoye	viability	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	0.9921378822270295	[25]	[38]	6	hSpCas9	negative selection	156321
4204572	4204595	16	+	26472758	Jiyoye	viability	GGGTCTTCTCGATGTGGGAGCGG	SRL	ENSG00000185739	1.023846741954368	[14]	[22]	6	hSpCas9	negative selection	156322
4197889	4197912	16	-	26472758	Jiyoye	viability	AGAGATTACCTCCAAGCCCATGG	SRL	ENSG00000185739	-0.5521826339967805	[209]	[107]	-4	hSpCas9	negative selection	156323
4197873	4197896	16	+	26472758	Jiyoye	viability	GGTCCCAGGAACAGTACCATGGG	SRL	ENSG00000185739	0.4015288183647314	[255]	[254]	3	hSpCas9	negative selection	156324
4195752	4195775	16	+	26472758	KBM7	viability	GAGGACCGTGAACTCAGAGGTGG	SRL	ENSG00000185739	-0.6890226162491992	[320,310]	[130,57]	-5	hSpCas9	negative selection	347433
4195721	4195744	16	-	26472758	KBM7	viability	GCCTAAGCTGAAAACCATCGAGG	SRL	ENSG00000185739	0.02216113255320934	[243,411]	[161,160]	0	hSpCas9	negative selection	347434
4197817	4197840	16	+	26472758	KBM7	viability	GAGTATTTTCCAGCCCAAGGAGG	SRL	ENSG00000185739	-0.01432074355133861	[1062,639]	[420,358]	0	hSpCas9	negative selection	347435
4204626	4204649	16	-	26472758	KBM7	viability	GCTTCTCTCCACAGAAGAGACGG	SRL	ENSG00000185739	-0.6009493024374767	[394,428]	[149,109]	-5	hSpCas9	negative selection	347436
4204557	4204580	16	-	26472758	KBM7	viability	GAAGACCCTCATGCTGAATGAGG	SRL	ENSG00000185739	0.03041450856104677	[1129,971]	[686,338]	0	hSpCas9	negative selection	347437
4197826	4197849	16	-	26472758	KBM7	viability	GATAAACTACCTCCTTGGGCTGG	SRL	ENSG00000185739	0.03500632092747688	[595,477]	[293,223]	0	hSpCas9	negative selection	347438
4242055	4242078	16	-	26472758	KBM7	viability	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	-0.07999072565476084	[304,229]	[110,123]	-1	hSpCas9	negative selection	347439
4204572	4204595	16	+	26472758	KBM7	viability	GGGTCTTCTCGATGTGGGAGCGG	SRL	ENSG00000185739	-0.24826407838211773	[361,260]	[114,127]	-2	hSpCas9	negative selection	347440
4197889	4197912	16	-	26472758	KBM7	viability	AGAGATTACCTCCAAGCCCATGG	SRL	ENSG00000185739	0.04862905908665616	[670,490]	[289,269]	0	hSpCas9	negative selection	347441
4197873	4197896	16	+	26472758	KBM7	viability	GGTCCCAGGAACAGTACCATGGG	SRL	ENSG00000185739	-0.06385100353058859	[1272,1336]	[527,647]	0	hSpCas9	negative selection	347442
4195752	4195775	16	+	26472758	Raji	viability	GAGGACCGTGAACTCAGAGGTGG	SRL	ENSG00000185739	-0.3621017479276206	[215]	[38]	-3	hSpCas9	negative selection	538551
4195721	4195744	16	-	26472758	Raji	viability	GCCTAAGCTGAAAACCATCGAGG	SRL	ENSG00000185739	0.06856428648307138	[225]	[54]	0	hSpCas9	negative selection	538552
4197817	4197840	16	+	26472758	Raji	viability	GAGTATTTTCCAGCCCAAGGAGG	SRL	ENSG00000185739	1.0983383957705926	[319]	[158]	8	hSpCas9	negative selection	538553
4204626	4204649	16	-	26472758	Raji	viability	GCTTCTCTCCACAGAAGAGACGG	SRL	ENSG00000185739	0.6089300279071181	[177]	[62]	6	hSpCas9	negative selection	538554
4204557	4204580	16	-	26472758	Raji	viability	GAAGACCCTCATGCTGAATGAGG	SRL	ENSG00000185739	-0.1095749999122202	[529]	[113]	-1	hSpCas9	negative selection	538555
4197826	4197849	16	-	26472758	Raji	viability	GATAAACTACCTCCTTGGGCTGG	SRL	ENSG00000185739	-0.0011409214045695892	[275]	[63]	0	hSpCas9	negative selection	538556
4242055	4242078	16	-	26472758	Raji	viability	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	-0.8646020884568038	[101]	[12]	-6	hSpCas9	negative selection	538557
4204572	4204595	16	+	26472758	Raji	viability	GGGTCTTCTCGATGTGGGAGCGG	SRL	ENSG00000185739	-0.18384776229084626	[185]	[37]	-1	hSpCas9	negative selection	538558
4197889	4197912	16	-	26472758	Raji	viability	AGAGATTACCTCCAAGCCCATGG	SRL	ENSG00000185739	0.7767382233851281	[331]	[131]	7	hSpCas9	negative selection	538559
4197873	4197896	16	+	26472758	Raji	viability	GGTCCCAGGAACAGTACCATGGG	SRL	ENSG00000185739	0.3287799642363234	[620]	[180]	3	hSpCas9	negative selection	538560
4195752	4195775	16	+	26472758	K562	viability	GAGGACCGTGAACTCAGAGGTGG	SRL	ENSG00000185739	-2.15127342189297	[320]	[60]	-7	hSpCas9	negative selection	729669
4195721	4195744	16	-	26472758	K562	viability	GCCTAAGCTGAAAACCATCGAGG	SRL	ENSG00000185739	0.5915409047130598	[385]	[490]	5	hSpCas9	negative selection	729670
4197817	4197840	16	+	26472758	K562	viability	GAGTATTTTCCAGCCCAAGGAGG	SRL	ENSG00000185739	0.04456616575313466	[687]	[598]	0	hSpCas9	negative selection	729671
4204626	4204649	16	-	26472758	K562	viability	GCTTCTCTCCACAGAAGAGACGG	SRL	ENSG00000185739	0.008561582902752107	[304]	[258]	0	hSpCas9	negative selection	729672
4204557	4204580	16	-	26472758	K562	viability	GAAGACCCTCATGCTGAATGAGG	SRL	ENSG00000185739	-0.26055127687391166	[876]	[617]	-2	hSpCas9	negative selection	729673
4197826	4197849	16	-	26472758	K562	viability	GATAAACTACCTCCTTGGGCTGG	SRL	ENSG00000185739	0.9736348222277184	[335]	[556]	7	hSpCas9	negative selection	729674
4242055	4242078	16	-	26472758	K562	viability	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	0.33957596070678703	[219]	[234]	2	hSpCas9	negative selection	729675
4204572	4204595	16	+	26472758	K562	viability	GGGTCTTCTCGATGTGGGAGCGG	SRL	ENSG00000185739	1.5663468225538093	[169]	[424]	9	hSpCas9	negative selection	729676
4197889	4197912	16	-	26472758	K562	viability	AGAGATTACCTCCAAGCCCATGG	SRL	ENSG00000185739	0.43967501906538087	[413]	[473]	3	hSpCas9	negative selection	729677
4197873	4197896	16	+	26472758	K562	viability	GGTCCCAGGAACAGTACCATGGG	SRL	ENSG00000185739	0.21086616795542024	[782]	[764]	1	hSpCas9	negative selection	729678
4192723	4192746	16	+	26627737	DLD1	viability	CTCTGTGACATTGATGAGAGGGG	SRL	ENSG00000185739	0.40624590780230285	[1017]	[324,367,549]	4	hSpCas9	negative selection	794091
4195552	4195575	16	-	26627737	DLD1	viability	AACCGCAAGCAGCAAGAAAGAGG	SRL	ENSG00000185739	-0.28253261286182096	[695]	[136,201,195]	-3	hSpCas9	negative selection	794092
4197872	4197895	16	+	26627737	DLD1	viability	CGGTCCCAGGAACAGTACCATGG	SRL	ENSG00000185739	-0.32824471071800776	[925]	[359,230,117]	-3	hSpCas9	negative selection	794093
4204529	4204552	16	+	26627737	DLD1	viability	TTACCAGAGTAGTCATCGGATGG	SRL	ENSG00000185739	-0.057626723057425555	[320]	[131,49,103]	0	hSpCas9	negative selection	794094
4207168	4207191	16	+	26627737	DLD1	viability	TCTTCGGACTCCTCTTCGGAGGG	SRL	ENSG00000185739	0.6370676632320558	[168]	[34,115,94]	6	hSpCas9	negative selection	794095
4207363	4207386	16	-	26627737	DLD1	viability	AGTGAGGGCACCGAGGACCAGGG	SRL	ENSG00000185739	-3.845681625315782	[493]	[15,16,0]	-9	hSpCas9	negative selection	794096
4192723	4192746	16	+	26627737	GBM cells	viability after 5 days	CTCTGTGACATTGATGAGAGGGG	SRL	ENSG00000185739	0.48968199728804773	[495]	[393,352]	7	hSpCas9	negative selection	876406
4195552	4195575	16	-	26627737	GBM cells	viability after 5 days	AACCGCAAGCAGCAAGAAAGAGG	SRL	ENSG00000185739	0.367967407460688	[556]	[285,484]	5	hSpCas9	negative selection	876407
4197872	4197895	16	+	26627737	GBM cells	viability after 5 days	CGGTCCCAGGAACAGTACCATGG	SRL	ENSG00000185739	0.13571673914629978	[369]	[228,206]	2	hSpCas9	negative selection	876408
4204529	4204552	16	+	26627737	GBM cells	viability after 5 days	TTACCAGAGTAGTCATCGGATGG	SRL	ENSG00000185739	0.2208419697730479	[179]	[106,117]	3	hSpCas9	negative selection	876409
4207168	4207191	16	+	26627737	GBM cells	viability after 5 days	TCTTCGGACTCCTCTTCGGAGGG	SRL	ENSG00000185739	0.17153432954867753	[124]	[68,81]	2	hSpCas9	negative selection	876410
4207363	4207386	16	-	26627737	GBM cells	viability after 5 days	AGTGAGGGCACCGAGGACCAGGG	SRL	ENSG00000185739	-0.5060699597292355	[142]	[42,64]	-7	hSpCas9	negative selection	876411
4192723	4192746	16	+	26627737	GBM cells	viability after 13 days	CTCTGTGACATTGATGAGAGGGG	SRL	ENSG00000185739	0.44247584224515646	[495]	[341,384]	5	hSpCas9	negative selection	958721
4195552	4195575	16	-	26627737	GBM cells	viability after 13 days	AACCGCAAGCAGCAAGAAAGAGG	SRL	ENSG00000185739	0.4634552617399903	[556]	[451,387]	6	hSpCas9	negative selection	958722
4197872	4197895	16	+	26627737	GBM cells	viability after 13 days	CGGTCCCAGGAACAGTACCATGG	SRL	ENSG00000185739	0.2155450606238406	[369]	[231,233]	2	hSpCas9	negative selection	958723
4204529	4204552	16	+	26627737	GBM cells	viability after 13 days	TTACCAGAGTAGTCATCGGATGG	SRL	ENSG00000185739	0.7620907187794839	[179]	[190,144]	8	hSpCas9	negative selection	958724
4207168	4207191	16	+	26627737	GBM cells	viability after 13 days	TCTTCGGACTCCTCTTCGGAGGG	SRL	ENSG00000185739	0.08078215516240961	[124]	[79,64]	1	hSpCas9	negative selection	958725
4207363	4207386	16	-	26627737	GBM cells	viability after 13 days	AGTGAGGGCACCGAGGACCAGGG	SRL	ENSG00000185739	-1.1403249637305153	[142]	[16,49]	-8	hSpCas9	negative selection	958726
4192723	4192746	16	+	26627737	GBM cells	viability after 21 days	CTCTGTGACATTGATGAGAGGGG	SRL	ENSG00000185739	1.085740169932515	[495]	[596,548]	9	hSpCas9	negative selection	1041036
4195552	4195575	16	-	26627737	GBM cells	viability after 21 days	AACCGCAAGCAGCAAGAAAGAGG	SRL	ENSG00000185739	0.7808826225439214	[556]	[544,496]	7	hSpCas9	negative selection	1041037
4197872	4197895	16	+	26627737	GBM cells	viability after 21 days	CGGTCCCAGGAACAGTACCATGG	SRL	ENSG00000185739	0.3853307516308807	[369]	[272,252]	4	hSpCas9	negative selection	1041038
4204529	4204552	16	+	26627737	GBM cells	viability after 21 days	TTACCAGAGTAGTCATCGGATGG	SRL	ENSG00000185739	0.6983364913999919	[179]	[177,140]	7	hSpCas9	negative selection	1041039
4207168	4207191	16	+	26627737	GBM cells	viability after 21 days	TCTTCGGACTCCTCTTCGGAGGG	SRL	ENSG00000185739	0.5137006770003963	[124]	[97,95]	5	hSpCas9	negative selection	1041040
4207363	4207386	16	-	26627737	GBM cells	viability after 21 days	AGTGAGGGCACCGAGGACCAGGG	SRL	ENSG00000185739	-0.5795066201320951	[142]	[63,40]	-5	hSpCas9	negative selection	1041041
4192723	4192746	16	+	26627737	RPE1	viability after 9 days	CTCTGTGACATTGATGAGAGGGG	SRL	ENSG00000185739	0.08375497897967676	[2263]	[610,931]	0	hSpCas9	negative selection	1123351
4195552	4195575	16	-	26627737	RPE1	viability after 9 days	AACCGCAAGCAGCAAGAAAGAGG	SRL	ENSG00000185739	-0.4864491342184236	[2481]	[527,588]	-3	hSpCas9	negative selection	1123352
4197872	4197895	16	+	26627737	RPE1	viability after 9 days	CGGTCCCAGGAACAGTACCATGG	SRL	ENSG00000185739	2.3291217811199902	[409]	[613,684]	9	hSpCas9	negative selection	1123353
4204529	4204552	16	+	26627737	RPE1	viability after 9 days	TTACCAGAGTAGTCATCGGATGG	SRL	ENSG00000185739	-1.4618244712380766	[733]	[75,92]	-8	hSpCas9	negative selection	1123354
4207168	4207191	16	+	26627737	RPE1	viability after 9 days	TCTTCGGACTCCTCTTCGGAGGG	SRL	ENSG00000185739	-0.06934557993865031	[524]	[198,101]	0	hSpCas9	negative selection	1123355
4207363	4207386	16	-	26627737	RPE1	viability after 9 days	AGTGAGGGCACCGAGGACCAGGG	SRL	ENSG00000185739	-4.021381188598913	[544]	[13,5]	-9	hSpCas9	negative selection	1123356
4192723	4192746	16	+	26627737	RPE1	viability after 12 days	CTCTGTGACATTGATGAGAGGGG	SRL	ENSG00000185739	-0.13517673346516812	[2263]	[463,648]	-1	hSpCas9	negative selection	1205666
4195552	4195575	16	-	26627737	RPE1	viability after 12 days	AACCGCAAGCAGCAAGAAAGAGG	SRL	ENSG00000185739	0.09681350690744939	[2481]	[716,708]	0	hSpCas9	negative selection	1205667
4197872	4197895	16	+	26627737	RPE1	viability after 12 days	CGGTCCCAGGAACAGTACCATGG	SRL	ENSG00000185739	1.5749371416087552	[409]	[435,213]	8	hSpCas9	negative selection	1205668
4204529	4204552	16	+	26627737	RPE1	viability after 12 days	TTACCAGAGTAGTCATCGGATGG	SRL	ENSG00000185739	-1.1924750239026	[733]	[78,93]	-7	hSpCas9	negative selection	1205669
4207168	4207191	16	+	26627737	RPE1	viability after 12 days	TCTTCGGACTCCTCTTCGGAGGG	SRL	ENSG00000185739	-0.1500798346495269	[524]	[164,86]	-1	hSpCas9	negative selection	1205670
4207363	4207386	16	-	26627737	RPE1	viability after 12 days	AGTGAGGGCACCGAGGACCAGGG	SRL	ENSG00000185739	-2.4809336815223095	[544]	[33,17]	-9	hSpCas9	negative selection	1205671
4192723	4192746	16	+	26627737	RPE1	viability after 15 days	CTCTGTGACATTGATGAGAGGGG	SRL	ENSG00000185739	0.039639460164509144	[2263]	[473,835]	0	hSpCas9	negative selection	1287981
4195552	4195575	16	-	26627737	RPE1	viability after 15 days	AACCGCAAGCAGCAAGAAAGAGG	SRL	ENSG00000185739	-0.19289623812112988	[2481]	[797,436]	-1	hSpCas9	negative selection	1287982
4197872	4197895	16	+	26627737	RPE1	viability after 15 days	CGGTCCCAGGAACAGTACCATGG	SRL	ENSG00000185739	1.86952703601371	[409]	[490,358]	8	hSpCas9	negative selection	1287983
4204529	4204552	16	+	26627737	RPE1	viability after 15 days	TTACCAGAGTAGTCATCGGATGG	SRL	ENSG00000185739	-1.2673402212504143	[733]	[99,72]	-7	hSpCas9	negative selection	1287984
4207168	4207191	16	+	26627737	RPE1	viability after 15 days	TCTTCGGACTCCTCTTCGGAGGG	SRL	ENSG00000185739	-0.5114137622069619	[524]	[149,59]	-3	hSpCas9	negative selection	1287985
4207363	4207386	16	-	26627737	RPE1	viability after 15 days	AGTGAGGGCACCGAGGACCAGGG	SRL	ENSG00000185739	-3.923123892783225	[544]	[0,18]	-9	hSpCas9	negative selection	1287986
4192723	4192746	16	+	26627737	RPE1	viability after 18 days	CTCTGTGACATTGATGAGAGGGG	SRL	ENSG00000185739	0.1952244755510597	[2263]	[699,698]	1	hSpCas9	negative selection	1370296
4195552	4195575	16	-	26627737	RPE1	viability after 18 days	AACCGCAAGCAGCAAGAAAGAGG	SRL	ENSG00000185739	-0.16819825375622655	[2481]	[569,623]	-1	hSpCas9	negative selection	1370297
4197872	4197895	16	+	26627737	RPE1	viability after 18 days	CGGTCCCAGGAACAGTACCATGG	SRL	ENSG00000185739	1.6200214500263077	[409]	[313,367]	8	hSpCas9	negative selection	1370298
4204529	4204552	16	+	26627737	RPE1	viability after 18 days	TTACCAGAGTAGTCATCGGATGG	SRL	ENSG00000185739	-1.6860644373634286	[733]	[106,12]	-7	hSpCas9	negative selection	1370299
4207168	4207191	16	+	26627737	RPE1	viability after 18 days	TCTTCGGACTCCTCTTCGGAGGG	SRL	ENSG00000185739	-0.9018202564978406	[524]	[99,49]	-5	hSpCas9	negative selection	1370300
4207363	4207386	16	-	26627737	RPE1	viability after 18 days	AGTGAGGGCACCGAGGACCAGGG	SRL	ENSG00000185739	-3.201726745252605	[544]	[0,31]	-9	hSpCas9	negative selection	1370301
4192723	4192746	16	+	26627737	HeLa	viability after 8 days	CTCTGTGACATTGATGAGAGGGG	SRL	ENSG00000185739	0.3516272364780817	[726]	[476,344,404]	3	hSpCas9	negative selection	1452611
4195552	4195575	16	-	26627737	HeLa	viability after 8 days	AACCGCAAGCAGCAAGAAAGAGG	SRL	ENSG00000185739	0.3572520891720947	[787]	[448,433,436]	3	hSpCas9	negative selection	1452612
4197872	4197895	16	+	26627737	HeLa	viability after 8 days	CGGTCCCAGGAACAGTACCATGG	SRL	ENSG00000185739	-0.03880103614539443	[522]	[266,176,229]	0	hSpCas9	negative selection	1452613
4204529	4204552	16	+	26627737	HeLa	viability after 8 days	TTACCAGAGTAGTCATCGGATGG	SRL	ENSG00000185739	-0.5154361406394814	[432]	[264,90,72]	-5	hSpCas9	negative selection	1452614
4207168	4207191	16	+	26627737	HeLa	viability after 8 days	TCTTCGGACTCCTCTTCGGAGGG	SRL	ENSG00000185739	0.5227487141175424	[136]	[148,37,83]	4	hSpCas9	negative selection	1452615
4207363	4207386	16	-	26627737	HeLa	viability after 8 days	AGTGAGGGCACCGAGGACCAGGG	SRL	ENSG00000185739	0.6617638827839492	[129]	[67,35,154]	5	hSpCas9	negative selection	1452616
4192723	4192746	16	+	26627737	HeLa	viability after 12 days	CTCTGTGACATTGATGAGAGGGG	SRL	ENSG00000185739	0.5299582269949883	[726]	[321,425,550]	4	hSpCas9	negative selection	1534926
4195552	4195575	16	-	26627737	HeLa	viability after 12 days	AACCGCAAGCAGCAAGAAAGAGG	SRL	ENSG00000185739	0.05631629836280383	[787]	[356,228,441]	0	hSpCas9	negative selection	1534927
4197872	4197895	16	+	26627737	HeLa	viability after 12 days	CGGTCCCAGGAACAGTACCATGG	SRL	ENSG00000185739	0.20256546645863277	[522]	[398,130,232]	1	hSpCas9	negative selection	1534928
4204529	4204552	16	+	26627737	HeLa	viability after 12 days	TTACCAGAGTAGTCATCGGATGG	SRL	ENSG00000185739	-0.561763181332247	[432]	[141,123,97]	-5	hSpCas9	negative selection	1534929
4207168	4207191	16	+	26627737	HeLa	viability after 12 days	TCTTCGGACTCCTCTTCGGAGGG	SRL	ENSG00000185739	0.574783975434859	[136]	[91,57,105]	5	hSpCas9	negative selection	1534930
4207363	4207386	16	-	26627737	HeLa	viability after 12 days	AGTGAGGGCACCGAGGACCAGGG	SRL	ENSG00000185739	0.997615794844641	[129]	[13,145,154]	7	hSpCas9	negative selection	1534931
4192723	4192746	16	+	26627737	HeLa	viability after 15 days	CTCTGTGACATTGATGAGAGGGG	SRL	ENSG00000185739	0.648851026689528	[726]	[364,496,536]	5	hSpCas9	negative selection	1617241
4195552	4195575	16	-	26627737	HeLa	viability after 15 days	AACCGCAAGCAGCAAGAAAGAGG	SRL	ENSG00000185739	0.160722329945582	[787]	[252,370,460]	1	hSpCas9	negative selection	1617242
4197872	4197895	16	+	26627737	HeLa	viability after 15 days	CGGTCCCAGGAACAGTACCATGG	SRL	ENSG00000185739	0.0025215555953647106	[522]	[132,389,109]	0	hSpCas9	negative selection	1617243
4204529	4204552	16	+	26627737	HeLa	viability after 15 days	TTACCAGAGTAGTCATCGGATGG	SRL	ENSG00000185739	-0.8986916979634614	[432]	[136,88,53]	-7	hSpCas9	negative selection	1617244
4207168	4207191	16	+	26627737	HeLa	viability after 15 days	TCTTCGGACTCCTCTTCGGAGGG	SRL	ENSG00000185739	0.6341845507363442	[136]	[24,33,210]	5	hSpCas9	negative selection	1617245
4207363	4207386	16	-	26627737	HeLa	viability after 15 days	AGTGAGGGCACCGAGGACCAGGG	SRL	ENSG00000185739	-0.3783087092209667	[129]	[0,100,18]	-3	hSpCas9	negative selection	1617246
4192723	4192746	16	+	26627737	HeLa	viability after 18 days	CTCTGTGACATTGATGAGAGGGG	SRL	ENSG00000185739	0.6415986766397523	[726]	[239,411,536]	5	hSpCas9	negative selection	1699556
4195552	4195575	16	-	26627737	HeLa	viability after 18 days	AACCGCAAGCAGCAAGAAAGAGG	SRL	ENSG00000185739	0.1928082695087583	[787]	[179,313,460]	1	hSpCas9	negative selection	1699557
4197872	4197895	16	+	26627737	HeLa	viability after 18 days	CGGTCCCAGGAACAGTACCATGG	SRL	ENSG00000185739	-0.0036908291404559868	[522]	[84,325,109]	0	hSpCas9	negative selection	1699558
4204529	4204552	16	+	26627737	HeLa	viability after 18 days	TTACCAGAGTAGTCATCGGATGG	SRL	ENSG00000185739	-0.9536804167471038	[432]	[91,64,53]	-7	hSpCas9	negative selection	1699559
4207168	4207191	16	+	26627737	HeLa	viability after 18 days	TCTTCGGACTCCTCTTCGGAGGG	SRL	ENSG00000185739	0.6039107054157558	[136]	[14,25,210]	5	hSpCas9	negative selection	1699560
4207363	4207386	16	-	26627737	HeLa	viability after 18 days	AGTGAGGGCACCGAGGACCAGGG	SRL	ENSG00000185739	-0.24238458812435404	[129]	[0,92,18]	-2	hSpCas9	negative selection	1699561
4192723	4192746	16	+	26627737	HCT116	viability after 6 days	CTCTGTGACATTGATGAGAGGGG	SRL	ENSG00000185739	0.49617491485192655	[1370]	[167,378]	2	hSpCas9	negative selection	1781871
4195552	4195575	16	-	26627737	HCT116	viability after 6 days	AACCGCAAGCAGCAAGAAAGAGG	SRL	ENSG00000185739	-0.32636940524559255	[1344]	[225,136]	-2	hSpCas9	negative selection	1781872
4197872	4197895	16	+	26627737	HCT116	viability after 6 days	CGGTCCCAGGAACAGTACCATGG	SRL	ENSG00000185739	0.2963488637477185	[1326]	[348,204]	1	hSpCas9	negative selection	1781873
4204529	4204552	16	+	26627737	HCT116	viability after 6 days	TTACCAGAGTAGTCATCGGATGG	SRL	ENSG00000185739	-1.1326781434129558	[600]	[35,46]	-6	hSpCas9	negative selection	1781874
4207168	4207191	16	+	26627737	HCT116	viability after 6 days	TCTTCGGACTCCTCTTCGGAGGG	SRL	ENSG00000185739	0.9323036714481179	[252]	[4,114]	5	hSpCas9	negative selection	1781875
4207363	4207386	16	-	26627737	HCT116	viability after 6 days	AGTGAGGGCACCGAGGACCAGGG	SRL	ENSG00000185739	-0.9433873289286069	[573]	[102,15]	-5	hSpCas9	negative selection	1781876
4192723	4192746	16	+	26627737	HCT116	viability after 8 days	CTCTGTGACATTGATGAGAGGGG	SRL	ENSG00000185739	0.5690959403750804	[472]	[334,510,313]	6	hSpCas9	negative selection	1864186
4195552	4195575	16	-	26627737	HCT116	viability after 8 days	AACCGCAAGCAGCAAGAAAGAGG	SRL	ENSG00000185739	0.032723299594543453	[699]	[369,396,415]	0	hSpCas9	negative selection	1864187
4197872	4197895	16	+	26627737	HCT116	viability after 8 days	CGGTCCCAGGAACAGTACCATGG	SRL	ENSG00000185739	0.2949102840586654	[492]	[284,384,328]	3	hSpCas9	negative selection	1864188
4204529	4204552	16	+	26627737	HCT116	viability after 8 days	TTACCAGAGTAGTCATCGGATGG	SRL	ENSG00000185739	-0.4634435013473127	[202]	[61,96,83]	-5	hSpCas9	negative selection	1864189
4207168	4207191	16	+	26627737	HCT116	viability after 8 days	TCTTCGGACTCCTCTTCGGAGGG	SRL	ENSG00000185739	-1.41731586407586	[212]	[38,69,22]	-9	hSpCas9	negative selection	1864190
4207363	4207386	16	-	26627737	HCT116	viability after 8 days	AGTGAGGGCACCGAGGACCAGGG	SRL	ENSG00000185739	0.4498678415188022	[133]	[118,91,91]	5	hSpCas9	negative selection	1864191
4192723	4192746	16	+	26627737	HCT116	viability after 9 days	CTCTGTGACATTGATGAGAGGGG	SRL	ENSG00000185739	-0.12618341537051503	[1370]	[545,168]	-1	hSpCas9	negative selection	1946501
4195552	4195575	16	-	26627737	HCT116	viability after 9 days	AACCGCAAGCAGCAAGAAAGAGG	SRL	ENSG00000185739	-1.7913391668725183	[1344]	[86,116]	-8	hSpCas9	negative selection	1946502
4197872	4197895	16	+	26627737	HCT116	viability after 9 days	CGGTCCCAGGAACAGTACCATGG	SRL	ENSG00000185739	-0.5107889927258397	[1326]	[327,185]	-4	hSpCas9	negative selection	1946503
4204529	4204552	16	+	26627737	HCT116	viability after 9 days	TTACCAGAGTAGTCATCGGATGG	SRL	ENSG00000185739	-1.8442319938151448	[600]	[80,15]	-8	hSpCas9	negative selection	1946504
4207168	4207191	16	+	26627737	HCT116	viability after 9 days	TCTTCGGACTCCTCTTCGGAGGG	SRL	ENSG00000185739	0.8497475100909047	[252]	[23,198]	6	hSpCas9	negative selection	1946505
4207363	4207386	16	-	26627737	HCT116	viability after 9 days	AGTGAGGGCACCGAGGACCAGGG	SRL	ENSG00000185739	-1.9049033916155829	[573]	[12,62]	-8	hSpCas9	negative selection	1946506
4192723	4192746	16	+	26627737	HCT116	viability after 12 days	CTCTGTGACATTGATGAGAGGGG	SRL	ENSG00000185739	0.8623388085523878	[472]	[364,478,519]	7	hSpCas9	negative selection	2028816
4195552	4195575	16	-	26627737	HCT116	viability after 12 days	AACCGCAAGCAGCAAGAAAGAGG	SRL	ENSG00000185739	0.020783827596726923	[699]	[472,337,298]	0	hSpCas9	negative selection	2028817
4197872	4197895	16	+	26627737	HCT116	viability after 12 days	CGGTCCCAGGAACAGTACCATGG	SRL	ENSG00000185739	-0.18537889470593538	[492]	[164,266,257]	-2	hSpCas9	negative selection	2028818
4204529	4204552	16	+	26627737	HCT116	viability after 12 days	TTACCAGAGTAGTCATCGGATGG	SRL	ENSG00000185739	-0.35094483785244956	[202]	[69,77,103]	-4	hSpCas9	negative selection	2028819
4207168	4207191	16	+	26627737	HCT116	viability after 12 days	TCTTCGGACTCCTCTTCGGAGGG	SRL	ENSG00000185739	-1.1462989629181375	[212]	[10,83,60]	-8	hSpCas9	negative selection	2028820
4207363	4207386	16	-	26627737	HCT116	viability after 12 days	AGTGAGGGCACCGAGGACCAGGG	SRL	ENSG00000185739	-0.07221775746005266	[133]	[64,61,73]	0	hSpCas9	negative selection	2028821
4192723	4192746	16	+	26627737	HCT116	viability after 15 days	CTCTGTGACATTGATGAGAGGGG	SRL	ENSG00000185739	0.9907881670650294	[472]	[657,447,527]	8	hSpCas9	negative selection	2111131
4195552	4195575	16	-	26627737	HCT116	viability after 15 days	AACCGCAAGCAGCAAGAAAGAGG	SRL	ENSG00000185739	0.14553168543894768	[699]	[768,284,320]	1	hSpCas9	negative selection	2111132
4197872	4197895	16	+	26627737	HCT116	viability after 15 days	CGGTCCCAGGAACAGTACCATGG	SRL	ENSG00000185739	0.1440666660131884	[492]	[304,267,363]	1	hSpCas9	negative selection	2111133
4204529	4204552	16	+	26627737	HCT116	viability after 15 days	TTACCAGAGTAGTCATCGGATGG	SRL	ENSG00000185739	-0.3095772998974814	[202]	[91,99,89]	-3	hSpCas9	negative selection	2111134
4207168	4207191	16	+	26627737	HCT116	viability after 15 days	TCTTCGGACTCCTCTTCGGAGGG	SRL	ENSG00000185739	-1.4241959097646992	[212]	[36,77,20]	-8	hSpCas9	negative selection	2111135
4207363	4207386	16	-	26627737	HCT116	viability after 15 days	AGTGAGGGCACCGAGGACCAGGG	SRL	ENSG00000185739	0.5851548039921374	[133]	[177,63,111]	5	hSpCas9	negative selection	2111136
4192723	4192746	16	+	26627737	HCT116	viability after 18 days	CTCTGTGACATTGATGAGAGGGG	SRL	ENSG00000185739	0.8371020808393483	[472]	[566,330,328]	6	hSpCas9	negative selection	2193446
4195552	4195575	16	-	26627737	HCT116	viability after 18 days	AACCGCAAGCAGCAAGAAAGAGG	SRL	ENSG00000185739	0.6267583174916578	[699]	[560,614,378]	5	hSpCas9	negative selection	2193447
4197872	4197895	16	+	26627737	HCT116	viability after 18 days	CGGTCCCAGGAACAGTACCATGG	SRL	ENSG00000185739	0.31668772107565635	[492]	[354,328,199]	2	hSpCas9	negative selection	2193448
4204529	4204552	16	+	26627737	HCT116	viability after 18 days	TTACCAGAGTAGTCATCGGATGG	SRL	ENSG00000185739	0.16177139370055715	[202]	[129,95,103]	1	hSpCas9	negative selection	2193449
4207168	4207191	16	+	26627737	HCT116	viability after 18 days	TCTTCGGACTCCTCTTCGGAGGG	SRL	ENSG00000185739	-1.0060152452751114	[212]	[44,77,27]	-7	hSpCas9	negative selection	2193450
4207363	4207386	16	-	26627737	HCT116	viability after 18 days	AGTGAGGGCACCGAGGACCAGGG	SRL	ENSG00000185739	-0.04276137438280947	[133]	[93,72,18]	0	hSpCas9	negative selection	2193451
4235958	4235981	16	-	25494202	A375	resistance to PLX-4720 (puromycin)	ACCTCAGCCTCCCGAGTAGCCAG	SRL	ENSG00000185739	0.6074328335071536	[9,93]	[21,11]	2	dCas9-VP64	positive selection	2393247
4235958	4235981	16	-	25494202	A375	resistance to PLX-4720 (zeocin)	ACCTCAGCCTCCCGAGTAGCCAG	SRL	ENSG00000185739	-0.7211613622673668	[190,191]	[45,29]	-7	dCas9-VP64	positive selection	2488502
4204553	4204576	16	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTTGTCCTCATTCAGCATGAGGG	SRL	ENSG00000185739	0.46771915219211857	[3,3]	[3,5]	8	hSpCas9	positive selection	3023707
4204626	4204649	16	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTTCTCTCCACAGAAGAGACGG	SRL	ENSG00000185739	0.014438538163423664	[2,2]	[2,1]	0	hSpCas9	positive selection	3023708
4197853	4197876	16	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTAGATTTACCAACACTCCACGG	SRL	ENSG00000185739	-0.0015357694207749628	[3,4]	[4,2]	0	hSpCas9	positive selection	3023709
4242012	4242035	16	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTGTCCTGAGAACAGGAGCGAGG	SRL	ENSG00000185739	0.45795826287802394	[3,2]	[2,4]	8	hSpCas9	positive selection	3023710
4204553	4204576	16	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTTGTCCTCATTCAGCATGAGGG	SRL	ENSG00000185739	0.6174860268235277	[3,3]	[4,3]	8	hSpCas9	positive selection	3091565
4204626	4204649	16	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTTCTCTCCACAGAAGAGACGG	SRL	ENSG00000185739	-0.850096537192208	[2,2]	[1,0]	-9	hSpCas9	positive selection	3091566
4197853	4197876	16	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTAGATTTACCAACACTCCACGG	SRL	ENSG00000185739	-0.031244481303067895	[3,3]	[2,2]	0	hSpCas9	positive selection	3091567
4242012	4242035	16	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTGTCCTGAGAACAGGAGCGAGG	SRL	ENSG00000185739	-0.4952219368796981	[3,3]	[2,0]	-7	hSpCas9	positive selection	3091568
4204532	4204555		-	24336571	A375	resistance to PLX after 7 days	AAGCCATCCGATGACTACTCTGG	SRL	ENSG00000185739	0.06446759541561703	[9,12]	[9,13]	2	hSpCas9	positive selection	3147446
4204583	4204606		+	24336571	A375	resistance to PLX after 7 days	ATGTGGGAGCGGTCCCTCAATGG	SRL	ENSG00000185739	0.3785336713950045	[21,21]	[24,30]	8	hSpCas9	positive selection	3147447
4242055	4242078		-	24336571	A375	resistance to PLX after 7 days	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	-0.11994020460037502	[9,8]	[7,8]	-4	hSpCas9	positive selection	3147448
4242004	4242027		+	24336571	A375	resistance to PLX after 7 days	TACCTGCTTGTCCTGAGAACAGG	SRL	ENSG00000185739	0.5181215718833185	[10,9]	[13,16]	9	hSpCas9	positive selection	3147449
4204532	4204555		-	24336571	A375	resistance to PLX after 14 days	AAGCCATCCGATGACTACTCTGG	SRL	ENSG00000185739	-0.17702611718905248	[11,13]	[5,4]	-2	hSpCas9	positive selection	3205239
4204583	4204606		+	24336571	A375	resistance to PLX after 14 days	ATGTGGGAGCGGTCCCTCAATGG	SRL	ENSG00000185739	1.7439334789167213	[33,16]	[36,42]	9	hSpCas9	positive selection	3205240
4242055	4242078		-	24336571	A375	resistance to PLX after 14 days	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	-0.17292769089346005	[10,4]	[1,3]	-2	hSpCas9	positive selection	3205241
4242004	4242027		+	24336571	A375	resistance to PLX after 14 days	TACCTGCTTGTCCTGAGAACAGG	SRL	ENSG00000185739	0.013309514089602514	[14,16]	[5,8]	0	hSpCas9	positive selection	3205242
4204532	4204555		-	24336571	A375	viability after 7 days	AAGCCATCCGATGACTACTCTGG	SRL	ENSG00000185739	-0.44408704559974277	[15]	[9,12]	-6	hSpCas9	negative selection	3263032
4204583	4204606		+	24336571	A375	viability after 7 days	ATGTGGGAGCGGTCCCTCAATGG	SRL	ENSG00000185739	0.42804367607496746	[16]	[21,21]	6	hSpCas9	negative selection	3263033
4242055	4242078		-	24336571	A375	viability after 7 days	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	-0.17307828142188036	[10]	[9,8]	-2	hSpCas9	negative selection	3263034
4242004	4242027		+	24336571	A375	viability after 7 days	TACCTGCTTGTCCTGAGAACAGG	SRL	ENSG00000185739	0.042624813001571615	[10]	[10,9]	0	hSpCas9	negative selection	3263035
4204532	4204555		-	24336571	A375	viability after 14 days	AAGCCATCCGATGACTACTCTGG	SRL	ENSG00000185739	-0.22211984957609132	[15]	[11,13]	-3	hSpCas9	negative selection	3320825
4204583	4204606		+	24336571	A375	viability after 14 days	ATGTGGGAGCGGTCCCTCAATGG	SRL	ENSG00000185739	0.6806272382116811	[16]	[33,16]	8	hSpCas9	negative selection	3320826
4242055	4242078		-	24336571	A375	viability after 14 days	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	-0.4379666791064299	[10]	[10,4]	-5	hSpCas9	negative selection	3320827
4242004	4242027		+	24336571	A375	viability after 14 days	TACCTGCTTGTCCTGAGAACAGG	SRL	ENSG00000185739	0.6200759564912319	[10]	[14,16]	7	hSpCas9	negative selection	3320828
4203182	4203205	16	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCTACAAGTACAATGAGCTCCGG	SRL	ENSG00000185739	-0.4291743157373832	[205,205]	[0,0]	-3	hSpCas9	positive selection	3394948
4203163	4203186	16	+	27383988	293T	resistance to West Nile virus (flavivirus)	TACCTGTGATCTCATGCTGCCGG	SRL	ENSG00000185739	-1.2544264423215443	[364,364]	[0,0]	-8	hSpCas9	positive selection	3394949
4242004	4242027	16	+	27383988	293T	resistance to West Nile virus (flavivirus)	TACCTGCTTGTCCTGAGAACAGG	SRL	ENSG00000185739	-1.2818325996621964	[371,371]	[0,0]	-8	hSpCas9	positive selection	3394950
4204552	4204575	16	+	26780180	HT29	viability (Avana library 4 designs)	CTTGTCCTCATTCAGCATGAGGG	SRL	ENSG00000185739	0.945392962316118	[]	[]	3	hSpCas9	negative selection	3462376
4204626	4204649	16	-	26780180	HT29	viability (Avana library 4 designs)	GCTTCTCTCCACAGAAGAGACGG	SRL	ENSG00000185739	1.07578832586755	[]	[]	4	hSpCas9	negative selection	3462377
4197852	4197875	16	+	26780180	HT29	viability (Avana library 4 designs)	GTAGATTTACCAACACTCCACGG	SRL	ENSG00000185739	0.661361686693281	[]	[]	2	hSpCas9	negative selection	3462378
4242011	4242034	16	+	26780180	HT29	viability (Avana library 4 designs)	TTGTCCTGAGAACAGGAGCGAGG	SRL	ENSG00000185739	1.52550220501742	[]	[]	6	hSpCas9	negative selection	3462379
4197852	4197875	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTAGATTTACCAACACTCCACGG	SRL	ENSG00000185739	-5.52461987060849	[]	[]	-6	hSpCas9	negative selection	3563899
4204626	4204649	16	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTTCTCTCCACAGAAGAGACGG	SRL	ENSG00000185739	-2.97251602205617	[]	[]	-4	hSpCas9	negative selection	3563900
4242011	4242034	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTGTCCTGAGAACAGGAGCGAGG	SRL	ENSG00000185739	4.47420714676893	[]	[]	7	hSpCas9	negative selection	3563901
4204552	4204575	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTTGTCCTCATTCAGCATGAGGG	SRL	ENSG00000185739	0.537691254438329	[]	[]	0	hSpCas9	negative selection	3563902
4204529	4204552	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTACCAGAGTAGTCATCGGATGG	SRL	ENSG00000185739	0.620306746730318	[]	[]	0	hSpCas9	negative selection	3563903
4195659	4195682	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATTCTGGCCAAACTTCTCAAGGG	SRL	ENSG00000185739	-1.427109396468	[]	[]	-2	hSpCas9	negative selection	3563904
4197852	4197875	16	+	26780180	A375	viability (Avana lentiGuide)	GTAGATTTACCAACACTCCACGG	SRL	ENSG00000185739	-1.58412699176221	[]	[]	-3	hSpCas9	negative selection	3672558
4204626	4204649	16	-	26780180	A375	viability (Avana lentiGuide)	GCTTCTCTCCACAGAAGAGACGG	SRL	ENSG00000185739	-5.61003314033604	[]	[]	-8	hSpCas9	negative selection	3672559
4242011	4242034	16	+	26780180	A375	viability (Avana lentiGuide)	TTGTCCTGAGAACAGGAGCGAGG	SRL	ENSG00000185739	16.4349128796326	[]	[]	8	hSpCas9	negative selection	3672560
4204552	4204575	16	+	26780180	A375	viability (Avana lentiGuide)	CTTGTCCTCATTCAGCATGAGGG	SRL	ENSG00000185739	-2.2202675319545	[]	[]	-4	hSpCas9	negative selection	3672561
4204529	4204552	16	+	26780180	A375	viability (Avana lentiGuide)	TTACCAGAGTAGTCATCGGATGG	SRL	ENSG00000185739	-2.67081728613203	[]	[]	-5	hSpCas9	negative selection	3672562
4195659	4195682	16	+	26780180	A375	viability (Avana lentiGuide)	ATTCTGGCCAAACTTCTCAAGGG	SRL	ENSG00000185739	5.63179201012134	[]	[]	5	hSpCas9	negative selection	3672563
4197852	4197875	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTAGATTTACCAACACTCCACGG	SRL	ENSG00000185739	-0.4148374629066399	[6]	[4,3]	-6	hSpCas9	positive selection	3781165
4204626	4204649	16	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTTCTCTCCACAGAAGAGACGG	SRL	ENSG00000185739	-0.6845863618109589	[4]	[2,1]	-7	hSpCas9	positive selection	3781166
4242011	4242034	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTGTCCTGAGAACAGGAGCGAGG	SRL	ENSG00000185739	0.16569804037544533	[4]	[5,5]	4	hSpCas9	positive selection	3781167
4204552	4204575	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTTGTCCTCATTCAGCATGAGGG	SRL	ENSG00000185739	0.09897210232705501	[5]	[5,5]	2	hSpCas9	positive selection	3781168
4204529	4204552	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTACCAGAGTAGTCATCGGATGG	SRL	ENSG00000185739	-0.12428425877367372	[5]	[5,3]	-2	hSpCas9	positive selection	3781169
4195659	4195682	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATTCTGGCCAAACTTCTCAAGGG	SRL	ENSG00000185739	-0.20172908509670087	[5]	[3,4]	-3	hSpCas9	positive selection	3781170
4197852	4197875	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTAGATTTACCAACACTCCACGG	SRL	ENSG00000185739	0.22875185045542906	[5]	[5,5]	6	hSpCas9	positive selection	3889772
4204626	4204649	16	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTTCTCTCCACAGAAGAGACGG	SRL	ENSG00000185739	-0.002837586308456541	[4]	[3,2]	0	hSpCas9	positive selection	3889773
4242011	4242034	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTGTCCTGAGAACAGGAGCGAGG	SRL	ENSG00000185739	-0.4418153676383698	[5]	[3,2]	-5	hSpCas9	positive selection	3889774
4204552	4204575	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTTGTCCTCATTCAGCATGAGGG	SRL	ENSG00000185739	0.3276420745615364	[5]	[5,6]	8	hSpCas9	positive selection	3889775
4204529	4204552	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTACCAGAGTAGTCATCGGATGG	SRL	ENSG00000185739	0.09999974391014246	[4]	[4,4]	2	hSpCas9	positive selection	3889776
4195659	4195682	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATTCTGGCCAAACTTCTCAAGGG	SRL	ENSG00000185739	0.07907899903012806	[5]	[5,3]	1	hSpCas9	positive selection	3889777
4204532	4204555	16	-	26780180	A375	viability	AAGCCATCCGATGACTACTCTGG	SRL	ENSG00000185739	0.822323462610262	[]	[]	3	hSpCas9	negative selection	3999479
4204583	4204606	16	+	26780180	A375	viability	ATGTGGGAGCGGTCCCTCAATGG	SRL	ENSG00000185739	0.69365962880387	[]	[]	2	hSpCas9	negative selection	3999480
4203182	4203205	16	-	26780180	A375	viability	CCTACAAGTACAATGAGCTCCGG	SRL	ENSG00000185739	1.72303906281265	[]	[]	9	hSpCas9	negative selection	3999481
4242055	4242078	16	-	26780180	A375	viability	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	1.43295174796098	[]	[]	8	hSpCas9	negative selection	3999482
4242004	4242027	16	+	26780180	A375	viability	TACCTGCTTGTCCTGAGAACAGG	SRL	ENSG00000185739	1.37674587396495	[]	[]	7	hSpCas9	negative selection	3999483
4203163	4203186	16	+	26780180	A375	viability	TACCTGTGATCTCATGCTGCCGG	SRL	ENSG00000185739	1.13630728769161	[]	[]	6	hSpCas9	negative selection	3999484
4204532	4204555	16	-	26780180	HT29	viability (GeCKOv2 library)	AAGCCATCCGATGACTACTCTGG	SRL	ENSG00000185739	1.0117427143575	[]	[]	4	hSpCas9	negative selection	4107445
4204583	4204606	16	+	26780180	HT29	viability (GeCKOv2 library)	ATGTGGGAGCGGTCCCTCAATGG	SRL	ENSG00000185739	0.7582548278238	[]	[]	3	hSpCas9	negative selection	4107446
4203182	4203205	16	-	26780180	HT29	viability (GeCKOv2 library)	CCTACAAGTACAATGAGCTCCGG	SRL	ENSG00000185739	1.15229886773977	[]	[]	5	hSpCas9	negative selection	4107447
4242055	4242078	16	-	26780180	HT29	viability (GeCKOv2 library)	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	1.10592481574154	[]	[]	5	hSpCas9	negative selection	4107448
4242004	4242027	16	+	26780180	HT29	viability (GeCKOv2 library)	TACCTGCTTGTCCTGAGAACAGG	SRL	ENSG00000185739	0.82674412101321	[]	[]	3	hSpCas9	negative selection	4107449
4203163	4203186	16	+	26780180	HT29	viability (GeCKOv2 library)	TACCTGTGATCTCATGCTGCCGG	SRL	ENSG00000185739	0.472678719061463	[]	[]	1	hSpCas9	negative selection	4107450
4204532	4204555	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AAGCCATCCGATGACTACTCTGG	SRL	ENSG00000185739	-0.09587736923614075	[3]	[1,2]	-2	hSpCas9	positive selection	4173640
4204583	4204606	16	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATGTGGGAGCGGTCCCTCAATGG	SRL	ENSG00000185739	0.3155268666206208	[4]	[2,5]	7	hSpCas9	positive selection	4173641
4242055	4242078	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	-0.27378153712528785	[3]	[1,1]	-6	hSpCas9	positive selection	4173642
4242004	4242027	16	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TACCTGCTTGTCCTGAGAACAGG	SRL	ENSG00000185739	0.07003016650161958	[3]	[2,2]	1	hSpCas9	positive selection	4173643
4204532	4204555	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AAGCCATCCGATGACTACTCTGG	SRL	ENSG00000185739	1.5038260947887738	[3]	[5,3,4,3]	9	hSpCas9	positive selection	4237662
4204583	4204606	16	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATGTGGGAGCGGTCCCTCAATGG	SRL	ENSG00000185739	-0.4855684771617126	[3]	[0,0,1,0]	-7	hSpCas9	positive selection	4237663
4242055	4242078	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	-0.005795116770867803	[3]	[2,0,1,0]	0	hSpCas9	positive selection	4237664
4242004	4242027	16	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TACCTGCTTGTCCTGAGAACAGG	SRL	ENSG00000185739	-0.8362418510795189	[3]	[0,0,0,0]	-9	hSpCas9	positive selection	4237665
4204532	4204555	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAGCCATCCGATGACTACTCTGG	SRL	ENSG00000185739	-0.009465860666663495	[3]	[3,1]	0	hSpCas9	positive selection	4300615
4204583	4204606	16	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATGTGGGAGCGGTCCCTCAATGG	SRL	ENSG00000185739	-0.03345392202735313	[3]	[3,1]	0	hSpCas9	positive selection	4300616
4242055	4242078	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	0.2000871468686477	[2]	[1,2]	4	hSpCas9	positive selection	4300617
4203182	4203205	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTACAAGTACAATGAGCTCCGG	SRL	ENSG00000185739	-0.115158006232411	[3]	[2,1]	-2	hSpCas9	positive selection	4364870
4203163	4203186	16	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TACCTGTGATCTCATGCTGCCGG	SRL	ENSG00000185739	-0.14439773993674834	[3]	[3,1]	-3	hSpCas9	positive selection	4364871
4242004	4242027	16	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TACCTGCTTGTCCTGAGAACAGG	SRL	ENSG00000185739	-0.6380480272707895	[4]	[2,0]	-9	hSpCas9	positive selection	4364872
4192936	4192958	16	-	27760321	OCIAML3	viability	CTTCAACGACGTGTGCCAGTGG	SRL	ENSG00000185739	0.3602254456298412	[612,549]	[586,577]	4	hSpCas9	negative selection	4443167
4195568	4195590	16	+	27760321	OCIAML3	viability	TGCGGTTCTCGATGATGCCTGG	SRL	ENSG00000185739	-0.31116013893351124	[652,662]	[418,412]	-3	hSpCas9	negative selection	4443168
4195720	4195742	16	-	27760321	OCIAML3	viability	CTAAGCTGAAAACCATCGAGGG	SRL	ENSG00000185739	-0.004176080839646268	[267,205]	[159,213]	0	hSpCas9	negative selection	4443169
4197860	4197882	16	+	27760321	OCIAML3	viability	ACCAACACTCCACGGTCCCAGG	SRL	ENSG00000185739	0.4331428919773399	[1143,936]	[986,1231]	5	hSpCas9	negative selection	4443170
4204530	4204552	16	+	27760321	OCIAML3	viability	TACCAGAGTAGTCATCGGATGG	SRL	ENSG00000185739	0.3960340680861966	[344,274]	[284,358]	5	hSpCas9	negative selection	4443171
4192936	4192958	16	-	27760321	OCIAML2	viability	CTTCAACGACGTGTGCCAGTGG	SRL	ENSG00000185739	0.3354224140671526	[612,549]	[572,618]	4	hSpCas9	negative selection	4526630
4195568	4195590	16	+	27760321	OCIAML2	viability	TGCGGTTCTCGATGATGCCTGG	SRL	ENSG00000185739	0.20428328949582908	[652,662]	[518,742]	2	hSpCas9	negative selection	4526631
4195720	4195742	16	-	27760321	OCIAML2	viability	CTAAGCTGAAAACCATCGAGGG	SRL	ENSG00000185739	-0.5869034203310761	[267,205]	[108,149]	-6	hSpCas9	negative selection	4526632
4197860	4197882	16	+	27760321	OCIAML2	viability	ACCAACACTCCACGGTCCCAGG	SRL	ENSG00000185739	0.3681088524235083	[1143,936]	[923,1287]	5	hSpCas9	negative selection	4526633
4204530	4204552	16	+	27760321	OCIAML2	viability	TACCAGAGTAGTCATCGGATGG	SRL	ENSG00000185739	-0.24409095090086796	[344,274]	[140,301]	-3	hSpCas9	negative selection	4526634
4192936	4192958	16	-	27760321	MV411	viability	CTTCAACGACGTGTGCCAGTGG	SRL	ENSG00000185739	1.052869588041007	[612,549]	[777,820]	7	hSpCas9	negative selection	4610093
4195568	4195590	16	+	27760321	MV411	viability	TGCGGTTCTCGATGATGCCTGG	SRL	ENSG00000185739	0.07541196795544414	[652,662]	[583,271]	0	hSpCas9	negative selection	4610094
4195720	4195742	16	-	27760321	MV411	viability	CTAAGCTGAAAACCATCGAGGG	SRL	ENSG00000185739	1.267867523176095	[267,205]	[619,3]	8	hSpCas9	negative selection	4610095
4197860	4197882	16	+	27760321	MV411	viability	ACCAACACTCCACGGTCCCAGG	SRL	ENSG00000185739	0.9974502739554991	[1143,936]	[1288,1476]	7	hSpCas9	negative selection	4610096
4204530	4204552	16	+	27760321	MV411	viability	TACCAGAGTAGTCATCGGATGG	SRL	ENSG00000185739	-1.7522692902867947	[344,274]	[11,132]	-8	hSpCas9	negative selection	4610097
4192936	4192958	16	-	27760321	HL60	viability	CTTCAACGACGTGTGCCAGTGG	SRL	ENSG00000185739	0.4034817204027697	[612,549]	[546,712]	5	hSpCas9	negative selection	4693556
4195568	4195590	16	+	27760321	HL60	viability	TGCGGTTCTCGATGATGCCTGG	SRL	ENSG00000185739	-0.22821328186141648	[652,662]	[498,419]	-3	hSpCas9	negative selection	4693557
4195720	4195742	16	-	27760321	HL60	viability	CTAAGCTGAAAACCATCGAGGG	SRL	ENSG00000185739	-0.36094973074426817	[267,205]	[103,197]	-4	hSpCas9	negative selection	4693558
4197860	4197882	16	+	27760321	HL60	viability	ACCAACACTCCACGGTCCCAGG	SRL	ENSG00000185739	0.21633215013225215	[1143,936]	[887,1082]	2	hSpCas9	negative selection	4693559
4204530	4204552	16	+	27760321	HL60	viability	TACCAGAGTAGTCATCGGATGG	SRL	ENSG00000185739	-0.09949989426158012	[344,274]	[232,236]	-1	hSpCas9	negative selection	4693560
4192936	4192958	16	-	27760321	HT1080	viability	CTTCAACGACGTGTGCCAGTGG	SRL	ENSG00000185739	0.5910089106663988	[549,428]	[192,403]	3	hSpCas9	negative selection	4777019
4195568	4195590	16	+	27760321	HT1080	viability	TGCGGTTCTCGATGATGCCTGG	SRL	ENSG00000185739	1.3462999701251208	[662,517]	[769,409]	7	hSpCas9	negative selection	4777020
4195720	4195742	16	-	27760321	HT1080	viability	CTAAGCTGAAAACCATCGAGGG	SRL	ENSG00000185739	1.3586018867241167	[205,160]	[70,314]	7	hSpCas9	negative selection	4777021
4197860	4197882	16	+	27760321	HT1080	viability	ACCAACACTCCACGGTCCCAGG	SRL	ENSG00000185739	0.07980644277136473	[936,730]	[395,301]	0	hSpCas9	negative selection	4777022
4204530	4204552	16	+	27760321	HT1080	viability	TACCAGAGTAGTCATCGGATGG	SRL	ENSG00000185739	-0.2736009570874999	[274,214]	[85,74]	-1	hSpCas9	negative selection	4777023
4192936	4192958	16	-	27760321	HT29	viability after 7 days	CTTCAACGACGTGTGCCAGTGG	SRL	ENSG00000185739	0.31597855090273486	[549,428]	[1261,613,548]	5	hSpCas9	negative selection	4860482
4195568	4195590	16	+	27760321	HT29	viability after 7 days	TGCGGTTCTCGATGATGCCTGG	SRL	ENSG00000185739	0.02668550497089628	[662,517]	[843,671,811]	0	hSpCas9	negative selection	4860483
4195720	4195742	16	-	27760321	HT29	viability after 7 days	CTAAGCTGAAAACCATCGAGGG	SRL	ENSG00000185739	-0.1497643310065233	[205,160]	[186,358,91]	-2	hSpCas9	negative selection	4860484
4197860	4197882	16	+	27760321	HT29	viability after 7 days	ACCAACACTCCACGGTCCCAGG	SRL	ENSG00000185739	0.601043880711464	[936,730]	[1702,1659,1527]	8	hSpCas9	negative selection	4860485
4204530	4204552	16	+	27760321	HT29	viability after 7 days	TACCAGAGTAGTCATCGGATGG	SRL	ENSG00000185739	-0.030643266390822932	[274,214]	[495,288,170]	0	hSpCas9	negative selection	4860486
4192936	4192958	16	-	27760321	HT29	viability after 25 days	CTTCAACGACGTGTGCCAGTGG	SRL	ENSG00000185739	0.48967565071355024	[549,428]	[813,920,598]	5	hSpCas9	negative selection	4943945
4195568	4195590	16	+	27760321	HT29	viability after 25 days	TGCGGTTCTCGATGATGCCTGG	SRL	ENSG00000185739	0.3665309990263441	[662,517]	[767,859,1000]	4	hSpCas9	negative selection	4943946
4195720	4195742	16	-	27760321	HT29	viability after 25 days	CTAAGCTGAAAACCATCGAGGG	SRL	ENSG00000185739	0.4535089128089239	[205,160]	[243,184,451]	5	hSpCas9	negative selection	4943947
4197860	4197882	16	+	27760321	HT29	viability after 25 days	ACCAACACTCCACGGTCCCAGG	SRL	ENSG00000185739	0.8774811347735587	[936,730]	[1720,1824,1700]	8	hSpCas9	negative selection	4943948
4204530	4204552	16	+	27760321	HT29	viability after 25 days	TACCAGAGTAGTCATCGGATGG	SRL	ENSG00000185739	0.24742108569573462	[274,214]	[327,327,341]	2	hSpCas9	negative selection	4943949
4192936	4192958	16	-	27760321	HT29	viability after 22 days	CTTCAACGACGTGTGCCAGTGG	SRL	ENSG00000185739	0.6585196977735573	[549,428]	[1158,867,642]	7	hSpCas9	negative selection	5027408
4195568	4195590	16	+	27760321	HT29	viability after 22 days	TGCGGTTCTCGATGATGCCTGG	SRL	ENSG00000185739	0.485685933357638	[662,517]	[934,595,1340]	5	hSpCas9	negative selection	5027409
4195720	4195742	16	-	27760321	HT29	viability after 22 days	CTAAGCTGAAAACCATCGAGGG	SRL	ENSG00000185739	0.6018871532618777	[205,160]	[328,288,347]	6	hSpCas9	negative selection	5027410
4197860	4197882	16	+	27760321	HT29	viability after 22 days	ACCAACACTCCACGGTCCCAGG	SRL	ENSG00000185739	0.8542840582710223	[936,730]	[1925,1656,1639]	8	hSpCas9	negative selection	5027411
4204530	4204552	16	+	27760321	HT29	viability after 22 days	TACCAGAGTAGTCATCGGATGG	SRL	ENSG00000185739	0.30182075512458345	[274,214]	[506,317,216]	3	hSpCas9	negative selection	5027412
4192936	4192958	16	-	27760321	HT29	viability after 19 days	CTTCAACGACGTGTGCCAGTGG	SRL	ENSG00000185739	0.5374217134599698	[549,428]	[842,1102,505]	5	hSpCas9	negative selection	5110871
4195568	4195590	16	+	27760321	HT29	viability after 19 days	TGCGGTTCTCGATGATGCCTGG	SRL	ENSG00000185739	0.3532904728773283	[662,517]	[1033,609,957]	3	hSpCas9	negative selection	5110872
4195720	4195742	16	-	27760321	HT29	viability after 19 days	CTAAGCTGAAAACCATCGAGGG	SRL	ENSG00000185739	0.4631893979878997	[205,160]	[348,206,316]	4	hSpCas9	negative selection	5110873
4197860	4197882	16	+	27760321	HT29	viability after 19 days	ACCAACACTCCACGGTCCCAGG	SRL	ENSG00000185739	1.2005633693396514	[936,730]	[1728,2192,2588]	9	hSpCas9	negative selection	5110874
4204530	4204552	16	+	27760321	HT29	viability after 19 days	TACCAGAGTAGTCATCGGATGG	SRL	ENSG00000185739	0.018763301847906866	[274,214]	[315,472,73]	0	hSpCas9	negative selection	5110875
4192936	4192958	16	-	27760321	HT29	viability after 16 days	CTTCAACGACGTGTGCCAGTGG	SRL	ENSG00000185739	0.6382252160389351	[549,428]	[751,1059,729]	7	hSpCas9	negative selection	5194334
4195568	4195590	16	+	27760321	HT29	viability after 16 days	TGCGGTTCTCGATGATGCCTGG	SRL	ENSG00000185739	0.23902275348408641	[662,517]	[727,673,934]	2	hSpCas9	negative selection	5194335
4195720	4195742	16	-	27760321	HT29	viability after 16 days	CTAAGCTGAAAACCATCGAGGG	SRL	ENSG00000185739	0.9007168249599913	[205,160]	[218,321,594]	9	hSpCas9	negative selection	5194336
4197860	4197882	16	+	27760321	HT29	viability after 16 days	ACCAACACTCCACGGTCCCAGG	SRL	ENSG00000185739	0.9809736445984896	[936,730]	[1647,2010,1842]	9	hSpCas9	negative selection	5194337
4204530	4204552	16	+	27760321	HT29	viability after 16 days	TACCAGAGTAGTCATCGGATGG	SRL	ENSG00000185739	0.2818964981755128	[274,214]	[477,313,221]	3	hSpCas9	negative selection	5194338
4192936	4192958	16	-	27760321	HT29	viability after 13 days	CTTCAACGACGTGTGCCAGTGG	SRL	ENSG00000185739	0.46129878487760556	[549,428]	[1098,539,709]	6	hSpCas9	negative selection	5277797
4195568	4195590	16	+	27760321	HT29	viability after 13 days	TGCGGTTCTCGATGATGCCTGG	SRL	ENSG00000185739	0.38226825737455017	[662,517]	[992,955,738]	5	hSpCas9	negative selection	5277798
4195720	4195742	16	-	27760321	HT29	viability after 13 days	CTAAGCTGAAAACCATCGAGGG	SRL	ENSG00000185739	0.37053514404182786	[205,160]	[197,303,320]	5	hSpCas9	negative selection	5277799
4197860	4197882	16	+	27760321	HT29	viability after 13 days	ACCAACACTCCACGGTCCCAGG	SRL	ENSG00000185739	0.7840668978221579	[936,730]	[1512,1697,1779]	9	hSpCas9	negative selection	5277800
4204530	4204552	16	+	27760321	HT29	viability after 13 days	TACCAGAGTAGTCATCGGATGG	SRL	ENSG00000185739	0.1499449300362169	[274,214]	[341,355,251]	1	hSpCas9	negative selection	5277801
4192936	4192958	16	-	27760321	HT29	viability after 10 days	CTTCAACGACGTGTGCCAGTGG	SRL	ENSG00000185739	0.24159984393690015	[549,428]	[758,654,750]	3	hSpCas9	negative selection	5361260
4195568	4195590	16	+	27760321	HT29	viability after 10 days	TGCGGTTCTCGATGATGCCTGG	SRL	ENSG00000185739	0.128662058916448	[662,517]	[771,737,903]	1	hSpCas9	negative selection	5361261
4195720	4195742	16	-	27760321	HT29	viability after 10 days	CTAAGCTGAAAACCATCGAGGG	SRL	ENSG00000185739	0.17284314587280714	[205,160]	[276,152,339]	2	hSpCas9	negative selection	5361262
4197860	4197882	16	+	27760321	HT29	viability after 10 days	ACCAACACTCCACGGTCCCAGG	SRL	ENSG00000185739	0.6105412236360646	[936,730]	[1649,1737,1389]	8	hSpCas9	negative selection	5361263
4204530	4204552	16	+	27760321	HT29	viability after 10 days	TACCAGAGTAGTCATCGGATGG	SRL	ENSG00000185739	0.3232013912342511	[274,214]	[490,490,173]	4	hSpCas9	negative selection	5361264
4192936	4192958	16	-	27760321	MOLM13	viability	CTTCAACGACGTGTGCCAGTGG	SRL	ENSG00000185739	-0.3011461769765916	[612,549]	[326,213]	-2	hSpCas9	negative selection	5444723
4195568	4195590	16	+	27760321	MOLM13	viability	TGCGGTTCTCGATGATGCCTGG	SRL	ENSG00000185739	0.8609757583893904	[652,662]	[1195,234]	6	hSpCas9	negative selection	5444724
4195720	4195742	16	-	27760321	MOLM13	viability	CTAAGCTGAAAACCATCGAGGG	SRL	ENSG00000185739	-0.038497211342805704	[267,205]	[253,22]	0	hSpCas9	negative selection	5444725
4197860	4197882	16	+	27760321	MOLM13	viability	ACCAACACTCCACGGTCCCAGG	SRL	ENSG00000185739	0.5360304023068547	[1143,936]	[758,921]	4	hSpCas9	negative selection	5444726
4204530	4204552	16	+	27760321	MOLM13	viability	TACCAGAGTAGTCATCGGATGG	SRL	ENSG00000185739	-0.03763169120075416	[344,274]	[244,104]	0	hSpCas9	negative selection	5444727
4241685	4241708	16	-	27661255	K562	viability	GGCCCTCAAAGTCGAGACGGGGG	SRL	ENSG00000185739	0.058304705190208916	[515,574]	[542,375]	2	dCas9-KRAB	negative selection	5514282
4242001	4242024	16	-	27661255	K562	viability	GTTCTCAGGACAAGCAGGTAGGG	SRL	ENSG00000185739	0.18339021606080574	[842,1002]	[920,760]	6	dCas9-KRAB	negative selection	5514283
4204532	4204555	16	-	27260156	BXPC3	viability	AAGCCATCCGATGACTACTCTGG	SRL	ENSG00000185739	-0.46512384923887473	[552]	[385,487,362,435]	-7	hSpCas9	negative selection	5573075
4204583	4204606	16	+	27260156	BXPC3	viability	ATGTGGGAGCGGTCCCTCAATGG	SRL	ENSG00000185739	0.022747757556574363	[509]	[475,564,624,498]	0	hSpCas9	negative selection	5573076
4242055	4242078	16	-	27260156	BXPC3	viability	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	0.13224237237970446	[362]	[406,360,460,439]	3	hSpCas9	negative selection	5573077
4203182	4203205	16	-	27260156	BXPC3	viability	CCTACAAGTACAATGAGCTCCGG	SRL	ENSG00000185739	-0.12339567791289346	[494]	[483,311,520,605]	-3	hSpCas9	negative selection	5637330
4203163	4203186	16	+	27260156	BXPC3	viability	TACCTGTGATCTCATGCTGCCGG	SRL	ENSG00000185739	-0.18852437395864574	[928]	[726,843,923,933]	-4	hSpCas9	negative selection	5637331
4242004	4242027	16	+	27260156	BXPC3	viability	TACCTGCTTGTCCTGAGAACAGG	SRL	ENSG00000185739	-0.2815974956310916	[1046]	[676,866,948,1162]	-6	hSpCas9	negative selection	5637332
4204532	4204555	16	-	27260156	A673	viability	AAGCCATCCGATGACTACTCTGG	SRL	ENSG00000185739	-0.06442889641279559	[552]	[791,464,595,712]	-1	hSpCas9	negative selection	5694326
4204583	4204606	16	+	27260156	A673	viability	ATGTGGGAGCGGTCCCTCAATGG	SRL	ENSG00000185739	0.10290154751519619	[509]	[722,613,556,749]	2	hSpCas9	negative selection	5694327
4242055	4242078	16	-	27260156	A673	viability	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	0.1206988797960159	[362]	[602,320,546,439]	3	hSpCas9	negative selection	5694328
4203182	4203205	16	-	27260156	A673	viability	CCTACAAGTACAATGAGCTCCGG	SRL	ENSG00000185739	-0.15848130816716793	[494]	[707,472,433,536]	-4	hSpCas9	negative selection	5758581
4203163	4203186	16	+	27260156	A673	viability	TACCTGTGATCTCATGCTGCCGG	SRL	ENSG00000185739	-0.20029375187617937	[928]	[1054,975,902,956]	-5	hSpCas9	negative selection	5758582
4242004	4242027	16	+	27260156	A673	viability	TACCTGCTTGTCCTGAGAACAGG	SRL	ENSG00000185739	-0.148352791208189	[1046]	[1142,1063,1228,1098]	-4	hSpCas9	negative selection	5758583
4204532	4204555	16	-	27260156	A375	viability	AAGCCATCCGATGACTACTCTGG	SRL	ENSG00000185739	-0.10800074981009603	[552]	[759,675,650,349]	-1	hSpCas9	negative selection	5815577
4204583	4204606	16	+	27260156	A375	viability	ATGTGGGAGCGGTCCCTCAATGG	SRL	ENSG00000185739	0.293892337779935	[509]	[416,1014,880,651]	4	hSpCas9	negative selection	5815578
4242055	4242078	16	-	27260156	A375	viability	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	-0.2852362923652361	[362]	[376,487,196,347]	-4	hSpCas9	negative selection	5815579
4203182	4203205	16	-	27260156	A375	viability	CCTACAAGTACAATGAGCTCCGG	SRL	ENSG00000185739	-0.4274023718011446	[494]	[391,560,482,313]	-5	hSpCas9	negative selection	5879832
4203163	4203186	16	+	27260156	A375	viability	TACCTGTGATCTCATGCTGCCGG	SRL	ENSG00000185739	-0.1800170048171602	[928]	[697,1025,1245,874]	-3	hSpCas9	negative selection	5879833
4242004	4242027	16	+	27260156	A375	viability	TACCTGCTTGTCCTGAGAACAGG	SRL	ENSG00000185739	-0.2699101748113686	[1046]	[1255,893,993,906]	-4	hSpCas9	negative selection	5879834
4204532	4204555	16	-	27260156	COLO741	viability	AAGCCATCCGATGACTACTCTGG	SRL	ENSG00000185739	-0.10200299193768222	[552]	[791,720,484]	-2	hSpCas9	negative selection	5936828
4204583	4204606	16	+	27260156	COLO741	viability	ATGTGGGAGCGGTCCCTCAATGG	SRL	ENSG00000185739	0.29754696782909185	[509]	[815,908,685]	6	hSpCas9	negative selection	5936829
4242055	4242078	16	-	27260156	COLO741	viability	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	0.1300690556441496	[362]	[609,425,494]	2	hSpCas9	negative selection	5936830
4203182	4203205	16	-	27260156	COLO741	viability	CCTACAAGTACAATGAGCTCCGG	SRL	ENSG00000185739	-0.2699454911121674	[494]	[611,419,545]	-5	hSpCas9	negative selection	6001083
4203163	4203186	16	+	27260156	COLO741	viability	TACCTGTGATCTCATGCTGCCGG	SRL	ENSG00000185739	-0.39907190809143933	[928]	[1181,907,650]	-7	hSpCas9	negative selection	6001084
4242004	4242027	16	+	27260156	COLO741	viability	TACCTGCTTGTCCTGAGAACAGG	SRL	ENSG00000185739	-0.06819592347902881	[1046]	[1455,1302,1094]	-1	hSpCas9	negative selection	6001085
4204532	4204555	16	-	27260156	CAL120	viability	AAGCCATCCGATGACTACTCTGG	SRL	ENSG00000185739	0.07357515055052857	[552]	[613,840,700]	1	hSpCas9	negative selection	6058079
4204583	4204606	16	+	27260156	CAL120	viability	ATGTGGGAGCGGTCCCTCAATGG	SRL	ENSG00000185739	0.5446994852999656	[509]	[1297,782,754]	7	hSpCas9	negative selection	6058080
4242055	4242078	16	-	27260156	CAL120	viability	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	-0.27419367152081303	[362]	[562,327,259]	-4	hSpCas9	negative selection	6058081
4203182	4203205	16	-	27260156	CAL120	viability	CCTACAAGTACAATGAGCTCCGG	SRL	ENSG00000185739	-0.3313604786724663	[494]	[449,324,683]	-5	hSpCas9	negative selection	6122334
4203163	4203186	16	+	27260156	CAL120	viability	TACCTGTGATCTCATGCTGCCGG	SRL	ENSG00000185739	0.061639676547062816	[928]	[1382,1248,1016]	0	hSpCas9	negative selection	6122335
4242004	4242027	16	+	27260156	CAL120	viability	TACCTGCTTGTCCTGAGAACAGG	SRL	ENSG00000185739	-0.22684828114889366	[1046]	[1469,914,1009]	-3	hSpCas9	negative selection	6122336
4204532	4204555	16	-	27260156	CADOES1	viability	AAGCCATCCGATGACTACTCTGG	SRL	ENSG00000185739	0.0031685444714350808	[552]	[595,537,403,523]	0	hSpCas9	negative selection	6179330
4204583	4204606	16	+	27260156	CADOES1	viability	ATGTGGGAGCGGTCCCTCAATGG	SRL	ENSG00000185739	-0.06666333621778783	[509]	[466,530,380,431]	-1	hSpCas9	negative selection	6179331
4242055	4242078	16	-	27260156	CADOES1	viability	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	-0.2842570745303112	[362]	[190,219,318,382]	-5	hSpCas9	negative selection	6179332
4203182	4203205	16	-	27260156	CADOES1	viability	CCTACAAGTACAATGAGCTCCGG	SRL	ENSG00000185739	-0.27527214253965077	[494]	[290,438,359,433]	-5	hSpCas9	negative selection	6243585
4203163	4203186	16	+	27260156	CADOES1	viability	TACCTGTGATCTCATGCTGCCGG	SRL	ENSG00000185739	-0.5186177765854056	[928]	[696,568,649,491]	-7	hSpCas9	negative selection	6243586
4242004	4242027	16	+	27260156	CADOES1	viability	TACCTGCTTGTCCTGAGAACAGG	SRL	ENSG00000185739	-0.42335037810476894	[1046]	[669,627,712,899]	-6	hSpCas9	negative selection	6243587
4204532	4204555	16	-	27260156	EWS502	viability	AAGCCATCCGATGACTACTCTGG	SRL	ENSG00000185739	-0.04215312806465232	[552]	[457,571,692,564]	0	hSpCas9	negative selection	6300581
4204583	4204606	16	+	27260156	EWS502	viability	ATGTGGGAGCGGTCCCTCAATGG	SRL	ENSG00000185739	0.35621221256805086	[509]	[590,752,729,699]	6	hSpCas9	negative selection	6300582
4242055	4242078	16	-	27260156	EWS502	viability	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	0.11203932744498207	[362]	[344,441,412,471]	2	hSpCas9	negative selection	6300583
4203182	4203205	16	-	27260156	EWS502	viability	CCTACAAGTACAATGAGCTCCGG	SRL	ENSG00000185739	-0.480079981377658	[494]	[406,327,203,572]	-7	hSpCas9	negative selection	6364836
4203163	4203186	16	+	27260156	EWS502	viability	TACCTGTGATCTCATGCTGCCGG	SRL	ENSG00000185739	-0.2494750179382227	[928]	[768,859,726,965]	-4	hSpCas9	negative selection	6364837
4242004	4242027	16	+	27260156	EWS502	viability	TACCTGCTTGTCCTGAGAACAGG	SRL	ENSG00000185739	-0.17987775062502442	[1046]	[939,993,818,1174]	-3	hSpCas9	negative selection	6364838
4204532	4204555	16	-	27260156	EW8	viability	AAGCCATCCGATGACTACTCTGG	SRL	ENSG00000185739	-0.15768491062740753	[552]	[477,281,392,461]	-3	hSpCas9	negative selection	6421832
4204583	4204606	16	+	27260156	EW8	viability	ATGTGGGAGCGGTCCCTCAATGG	SRL	ENSG00000185739	-0.029171685018518745	[509]	[482,519,336,299]	0	hSpCas9	negative selection	6421833
4242055	4242078	16	-	27260156	EW8	viability	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	-0.14000183069733668	[362]	[406,233,156,302]	-3	hSpCas9	negative selection	6421834
4203182	4203205	16	-	27260156	EW8	viability	CCTACAAGTACAATGAGCTCCGG	SRL	ENSG00000185739	-0.1967514052153074	[494]	[528,361,249,294]	-4	hSpCas9	negative selection	6486087
4203163	4203186	16	+	27260156	EW8	viability	TACCTGTGATCTCATGCTGCCGG	SRL	ENSG00000185739	0.1259308995398325	[928]	[1095,903,667,672]	2	hSpCas9	negative selection	6486088
4242004	4242027	16	+	27260156	EW8	viability	TACCTGCTTGTCCTGAGAACAGG	SRL	ENSG00000185739	-0.03576598662800867	[1046]	[952,772,804,794]	0	hSpCas9	negative selection	6486089
4204532	4204555	16	-	27260156	CORL105	viability	AAGCCATCCGATGACTACTCTGG	SRL	ENSG00000185739	-0.039196420798395915	[552]	[668,601,730,535]	0	hSpCas9	negative selection	6543083
4204583	4204606	16	+	27260156	CORL105	viability	ATGTGGGAGCGGTCCCTCAATGG	SRL	ENSG00000185739	0.26187987965331266	[509]	[633,696,856,694]	5	hSpCas9	negative selection	6543084
4242055	4242078	16	-	27260156	CORL105	viability	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	-0.13060498638751278	[362]	[506,327,368,350]	-2	hSpCas9	negative selection	6543085
4203182	4203205	16	-	27260156	CORL105	viability	CCTACAAGTACAATGAGCTCCGG	SRL	ENSG00000185739	-0.6976600761207999	[494]	[313,430,386,298]	-8	hSpCas9	negative selection	6607338
4203163	4203186	16	+	27260156	CORL105	viability	TACCTGTGATCTCATGCTGCCGG	SRL	ENSG00000185739	-0.26541937270832494	[928]	[878,910,1080,774]	-5	hSpCas9	negative selection	6607339
4242004	4242027	16	+	27260156	CORL105	viability	TACCTGCTTGTCCTGAGAACAGG	SRL	ENSG00000185739	-0.17381554066623395	[1046]	[1017,1145,1252,951]	-3	hSpCas9	negative selection	6607340
4204532	4204555	16	-	27260156	HS294T	viability	AAGCCATCCGATGACTACTCTGG	SRL	ENSG00000185739	0.2573156610600972	[552]	[207,258,212,363]	3	hSpCas9	negative selection	6664334
4204583	4204606	16	+	27260156	HS294T	viability	ATGTGGGAGCGGTCCCTCAATGG	SRL	ENSG00000185739	0.18051456847618513	[509]	[262,190,139,310]	2	hSpCas9	negative selection	6664335
4242055	4242078	16	-	27260156	HS294T	viability	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	-0.11351491267099095	[362]	[106,146,146,116]	-1	hSpCas9	negative selection	6664336
4203182	4203205	16	-	27260156	HS294T	viability	CCTACAAGTACAATGAGCTCCGG	SRL	ENSG00000185739	-0.44699906963637065	[494]	[136,141,163,113]	-6	hSpCas9	negative selection	6728589
4203163	4203186	16	+	27260156	HS294T	viability	TACCTGTGATCTCATGCTGCCGG	SRL	ENSG00000185739	0.17622250798384775	[928]	[282,495,445,405]	2	hSpCas9	negative selection	6728590
4242004	4242027	16	+	27260156	HS294T	viability	TACCTGCTTGTCCTGAGAACAGG	SRL	ENSG00000185739	-0.16355804987274336	[1046]	[188,262,319,758]	-2	hSpCas9	negative selection	6728591
4204532	4204555	16	-	27260156	HCC44	viability	AAGCCATCCGATGACTACTCTGG	SRL	ENSG00000185739	0.15394076484766925	[552]	[825,358,1100,623]	2	hSpCas9	negative selection	6785585
4204583	4204606	16	+	27260156	HCC44	viability	ATGTGGGAGCGGTCCCTCAATGG	SRL	ENSG00000185739	0.43032335506611114	[509]	[923,771,896,551]	7	hSpCas9	negative selection	6785586
4242055	4242078	16	-	27260156	HCC44	viability	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	0.10599543653405175	[362]	[503,485,332,421]	1	hSpCas9	negative selection	6785587
4203182	4203205	16	-	27260156	HCC44	viability	CCTACAAGTACAATGAGCTCCGG	SRL	ENSG00000185739	-0.08273124637096187	[494]	[436,349,547,786]	-1	hSpCas9	negative selection	6849840
4203163	4203186	16	+	27260156	HCC44	viability	TACCTGTGATCTCATGCTGCCGG	SRL	ENSG00000185739	0.16280704690927572	[928]	[1022,994,1215,1469]	2	hSpCas9	negative selection	6849841
4242004	4242027	16	+	27260156	HCC44	viability	TACCTGCTTGTCCTGAGAACAGG	SRL	ENSG00000185739	-0.3475220922583594	[1046]	[982,579,1022,1190]	-5	hSpCas9	negative selection	6849842
4204532	4204555	16	-	27260156	G402	viability	AAGCCATCCGATGACTACTCTGG	SRL	ENSG00000185739	-0.11137021465817216	[552]	[581,547,634,715]	-1	hSpCas9	negative selection	6906836
4204583	4204606	16	+	27260156	G402	viability	ATGTGGGAGCGGTCCCTCAATGG	SRL	ENSG00000185739	0.21296460065617934	[509]	[578,463,1127,677]	2	hSpCas9	negative selection	6906837
4242055	4242078	16	-	27260156	G402	viability	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	0.5719928709002075	[362]	[740,1308,205,435]	7	hSpCas9	negative selection	6906838
4203182	4203205	16	-	27260156	G402	viability	CCTACAAGTACAATGAGCTCCGG	SRL	ENSG00000185739	-0.4313611969786144	[494]	[541,464,233,557]	-5	hSpCas9	negative selection	6971091
4203163	4203186	16	+	27260156	G402	viability	TACCTGTGATCTCATGCTGCCGG	SRL	ENSG00000185739	-0.2633423219047919	[928]	[1362,518,1241,697]	-3	hSpCas9	negative selection	6971092
4242004	4242027	16	+	27260156	G402	viability	TACCTGCTTGTCCTGAGAACAGG	SRL	ENSG00000185739	-0.08617096225973087	[1046]	[1303,1028,1454,1033]	-1	hSpCas9	negative selection	6971093
4204532	4204555	16	-	27260156	L33	viability	AAGCCATCCGATGACTACTCTGG	SRL	ENSG00000185739	-0.04355934388826738	[552]	[635,171,330,560]	-1	hSpCas9	negative selection	7028087
4204583	4204606	16	+	27260156	L33	viability	ATGTGGGAGCGGTCCCTCAATGG	SRL	ENSG00000185739	0.046708734700019836	[509]	[440,225,387,499]	1	hSpCas9	negative selection	7028088
4242055	4242078	16	-	27260156	L33	viability	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	-0.1376176463321001	[362]	[289,166,210,287]	-3	hSpCas9	negative selection	7028089
4203182	4203205	16	-	27260156	L33	viability	CCTACAAGTACAATGAGCTCCGG	SRL	ENSG00000185739	-0.451323822656052	[494]	[348,148,211,397]	-8	hSpCas9	negative selection	7092342
4203163	4203186	16	+	27260156	L33	viability	TACCTGTGATCTCATGCTGCCGG	SRL	ENSG00000185739	-0.4063983510727377	[928]	[708,272,481,661]	-7	hSpCas9	negative selection	7092343
4242004	4242027	16	+	27260156	L33	viability	TACCTGCTTGTCCTGAGAACAGG	SRL	ENSG00000185739	-0.17148123860788633	[1046]	[1083,376,479,945]	-4	hSpCas9	negative selection	7092344
4204532	4204555	16	-	27260156	K562	viability	AAGCCATCCGATGACTACTCTGG	SRL	ENSG00000185739	-0.10004114297208294	[552]	[599,472,386,389]	-1	hSpCas9	negative selection	7149338
4204583	4204606	16	+	27260156	K562	viability	ATGTGGGAGCGGTCCCTCAATGG	SRL	ENSG00000185739	0.020090333118826895	[509]	[645,463,427,326]	0	hSpCas9	negative selection	7149339
4242055	4242078	16	-	27260156	K562	viability	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	-1.1053517566551494	[362]	[186,147,170,100]	-8	hSpCas9	negative selection	7149340
4203182	4203205	16	-	27260156	K562	viability	CCTACAAGTACAATGAGCTCCGG	SRL	ENSG00000185739	-0.1174371632059717	[494]	[648,477,186,335]	-1	hSpCas9	negative selection	7213593
4203163	4203186	16	+	27260156	K562	viability	TACCTGTGATCTCATGCTGCCGG	SRL	ENSG00000185739	0.4242737812566775	[928]	[1488,1098,781,1083]	5	hSpCas9	negative selection	7213594
4242004	4242027	16	+	27260156	K562	viability	TACCTGCTTGTCCTGAGAACAGG	SRL	ENSG00000185739	-0.4831481679149099	[1046]	[819,870,591,424]	-5	hSpCas9	negative selection	7213595
4204532	4204555	16	-	27260156	HT29	viability	AAGCCATCCGATGACTACTCTGG	SRL	ENSG00000185739	-0.18566081215657526	[552]	[528,678,682,484]	-4	hSpCas9	negative selection	7270589
4204583	4204606	16	+	27260156	HT29	viability	ATGTGGGAGCGGTCCCTCAATGG	SRL	ENSG00000185739	0.19280975467239586	[509]	[871,541,780,640]	4	hSpCas9	negative selection	7270590
4242055	4242078	16	-	27260156	HT29	viability	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	0.3226938258986333	[362]	[603,643,447,522]	6	hSpCas9	negative selection	7270591
4203182	4203205	16	-	27260156	HT29	viability	CCTACAAGTACAATGAGCTCCGG	SRL	ENSG00000185739	-0.22682885907308598	[494]	[464,467,577,531]	-4	hSpCas9	negative selection	7334844
4203163	4203186	16	+	27260156	HT29	viability	TACCTGTGATCTCATGCTGCCGG	SRL	ENSG00000185739	0.0015254344222348504	[928]	[1412,962,1022,1122]	0	hSpCas9	negative selection	7334845
4242004	4242027	16	+	27260156	HT29	viability	TACCTGCTTGTCCTGAGAACAGG	SRL	ENSG00000185739	-0.14514118429661216	[1046]	[1305,1300,950,1071]	-3	hSpCas9	negative selection	7334846
4204532	4204555	16	-	27260156	MHHES1	viability	AAGCCATCCGATGACTACTCTGG	SRL	ENSG00000185739	0.0808133417086764	[552]	[739,523,774,592]	1	hSpCas9	negative selection	7391840
4204583	4204606	16	+	27260156	MHHES1	viability	ATGTGGGAGCGGTCCCTCAATGG	SRL	ENSG00000185739	-0.15939216482519522	[509]	[621,605,534,344]	-3	hSpCas9	negative selection	7391841
4242055	4242078	16	-	27260156	MHHES1	viability	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	-0.04559644630516546	[362]	[556,484,299,286]	-1	hSpCas9	negative selection	7391842
4203182	4203205	16	-	27260156	MHHES1	viability	CCTACAAGTACAATGAGCTCCGG	SRL	ENSG00000185739	-0.2613696924616451	[494]	[611,453,468,356]	-5	hSpCas9	negative selection	7456095
4203163	4203186	16	+	27260156	MHHES1	viability	TACCTGTGATCTCATGCTGCCGG	SRL	ENSG00000185739	-0.13433926032056231	[928]	[1158,982,1049,689]	-3	hSpCas9	negative selection	7456096
4242004	4242027	16	+	27260156	MHHES1	viability	TACCTGCTTGTCCTGAGAACAGG	SRL	ENSG00000185739	-0.4904794304229544	[1046]	[1130,892,804,604]	-7	hSpCas9	negative selection	7456097
4204532	4204555	16	-	27260156	MEWO	viability	AAGCCATCCGATGACTACTCTGG	SRL	ENSG00000185739	0.30839203233217194	[552]	[560,727,616]	6	hSpCas9	negative selection	7513091
4204583	4204606	16	+	27260156	MEWO	viability	ATGTGGGAGCGGTCCCTCAATGG	SRL	ENSG00000185739	0.27780820393844996	[509]	[669,573,508]	6	hSpCas9	negative selection	7513092
4242055	4242078	16	-	27260156	MEWO	viability	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	0.02809293687884623	[362]	[396,265,385]	0	hSpCas9	negative selection	7513093
4203182	4203205	16	-	27260156	MEWO	viability	CCTACAAGTACAATGAGCTCCGG	SRL	ENSG00000185739	-0.21088250647783036	[494]	[430,454,319]	-4	hSpCas9	negative selection	7577346
4203163	4203186	16	+	27260156	MEWO	viability	TACCTGTGATCTCATGCTGCCGG	SRL	ENSG00000185739	-0.26230632771369644	[928]	[795,642,748]	-5	hSpCas9	negative selection	7577347
4242004	4242027	16	+	27260156	MEWO	viability	TACCTGCTTGTCCTGAGAACAGG	SRL	ENSG00000185739	-0.2074907510155567	[1046]	[1048,774,759]	-4	hSpCas9	negative selection	7577348
4204532	4204555	16	-	27260156	LNCAPCLONEFGC	viability	AAGCCATCCGATGACTACTCTGG	SRL	ENSG00000185739	-0.16324050831415407	[552]	[514,247,568,486]	-3	hSpCas9	negative selection	7634342
4204583	4204606	16	+	27260156	LNCAPCLONEFGC	viability	ATGTGGGAGCGGTCCCTCAATGG	SRL	ENSG00000185739	0.5110953620264442	[509]	[523,676,836,622]	7	hSpCas9	negative selection	7634343
4242055	4242078	16	-	27260156	LNCAPCLONEFGC	viability	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	-0.1287802462640259	[362]	[303,259,297,342]	-2	hSpCas9	negative selection	7634344
4203182	4203205	16	-	27260156	LNCAPCLONEFGC	viability	CCTACAAGTACAATGAGCTCCGG	SRL	ENSG00000185739	0.0695515285039656	[494]	[390,303,588,627]	1	hSpCas9	negative selection	7698597
4203163	4203186	16	+	27260156	LNCAPCLONEFGC	viability	TACCTGTGATCTCATGCTGCCGG	SRL	ENSG00000185739	-0.5047147672723495	[928]	[609,659,617,482]	-6	hSpCas9	negative selection	7698598
4242004	4242027	16	+	27260156	LNCAPCLONEFGC	viability	TACCTGCTTGTCCTGAGAACAGG	SRL	ENSG00000185739	-0.4504718713925572	[1046]	[695,572,998,560]	-6	hSpCas9	negative selection	7698599
4204532	4204555	16	-	27260156	PANC0327	viability	AAGCCATCCGATGACTACTCTGG	SRL	ENSG00000185739	-0.27540248986802107	[552]	[468,322,321,524]	-4	hSpCas9	negative selection	7755593
4204583	4204606	16	+	27260156	PANC0327	viability	ATGTGGGAGCGGTCCCTCAATGG	SRL	ENSG00000185739	0.6347735151618359	[509]	[1086,655,587,519]	8	hSpCas9	negative selection	7755594
4242055	4242078	16	-	27260156	PANC0327	viability	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	-0.3459486466422576	[362]	[227,228,341,216]	-5	hSpCas9	negative selection	7755595
4203182	4203205	16	-	27260156	PANC0327	viability	CCTACAAGTACAATGAGCTCCGG	SRL	ENSG00000185739	-0.4868233629717901	[494]	[296,211,445,311]	-6	hSpCas9	negative selection	7819848
4203163	4203186	16	+	27260156	PANC0327	viability	TACCTGTGATCTCATGCTGCCGG	SRL	ENSG00000185739	-0.31497794789337186	[928]	[632,529,695,808]	-5	hSpCas9	negative selection	7819849
4242004	4242027	16	+	27260156	PANC0327	viability	TACCTGCTTGTCCTGAGAACAGG	SRL	ENSG00000185739	-0.5466307145408913	[1046]	[496,600,726,714]	-7	hSpCas9	negative selection	7819850
4204532	4204555	16	-	27260156	NCIH2009	viability	AAGCCATCCGATGACTACTCTGG	SRL	ENSG00000185739	0.2607440871496881	[552]	[1231,981,620]	3	hSpCas9	negative selection	7876844
4204583	4204606	16	+	27260156	NCIH2009	viability	ATGTGGGAGCGGTCCCTCAATGG	SRL	ENSG00000185739	0.2223809655417608	[509]	[854,785,856]	3	hSpCas9	negative selection	7876845
4242055	4242078	16	-	27260156	NCIH2009	viability	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	-0.2620246634358642	[362]	[505,505,270]	-4	hSpCas9	negative selection	7876846
4203182	4203205	16	-	27260156	NCIH2009	viability	CCTACAAGTACAATGAGCTCCGG	SRL	ENSG00000185739	-0.3444108242211392	[494]	[470,525,621]	-4	hSpCas9	negative selection	7941099
4203163	4203186	16	+	27260156	NCIH2009	viability	TACCTGTGATCTCATGCTGCCGG	SRL	ENSG00000185739	0.1166345237210975	[928]	[1382,1713,1111]	1	hSpCas9	negative selection	7941100
4242004	4242027	16	+	27260156	NCIH2009	viability	TACCTGCTTGTCCTGAGAACAGG	SRL	ENSG00000185739	-0.27344364129384957	[1046]	[1321,1088,1241]	-4	hSpCas9	negative selection	7941101
4204532	4204555	16	-	27260156	NCIH1373	viability	AAGCCATCCGATGACTACTCTGG	SRL	ENSG00000185739	-0.2637846440059518	[552]	[674,416,229,209]	-3	hSpCas9	negative selection	7998095
4204583	4204606	16	+	27260156	NCIH1373	viability	ATGTGGGAGCGGTCCCTCAATGG	SRL	ENSG00000185739	-0.17428563189641244	[509]	[733,413,451,122]	-2	hSpCas9	negative selection	7998096
4242055	4242078	16	-	27260156	NCIH1373	viability	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	-1.3549730235923032	[362]	[97,141,131,68]	-8	hSpCas9	negative selection	7998097
4203182	4203205	16	-	27260156	NCIH1373	viability	CCTACAAGTACAATGAGCTCCGG	SRL	ENSG00000185739	-0.42534051584189614	[494]	[362,407,354,137]	-4	hSpCas9	negative selection	8062350
4203163	4203186	16	+	27260156	NCIH1373	viability	TACCTGTGATCTCATGCTGCCGG	SRL	ENSG00000185739	0.13243038148174757	[928]	[1576,648,1071,367]	1	hSpCas9	negative selection	8062351
4242004	4242027	16	+	27260156	NCIH1373	viability	TACCTGCTTGTCCTGAGAACAGG	SRL	ENSG00000185739	-1.1704860212781873	[1046]	[520,373,776,108]	-8	hSpCas9	negative selection	8062352
4204532	4204555	16	-	27260156	PATU8902	viability	AAGCCATCCGATGACTACTCTGG	SRL	ENSG00000185739	-0.2704459884557223	[552]	[981,377,440,814]	-3	hSpCas9	negative selection	8119346
4204583	4204606	16	+	27260156	PATU8902	viability	ATGTGGGAGCGGTCCCTCAATGG	SRL	ENSG00000185739	0.025403260528233954	[509]	[791,569,559,1042]	0	hSpCas9	negative selection	8119347
4242055	4242078	16	-	27260156	PATU8902	viability	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	0.4314998177764396	[362]	[606,637,776,674]	4	hSpCas9	negative selection	8119348
4203182	4203205	16	-	27260156	PATU8902	viability	CCTACAAGTACAATGAGCTCCGG	SRL	ENSG00000185739	0.2277024117925685	[494]	[873,756,482,1243]	2	hSpCas9	negative selection	8183601
4203163	4203186	16	+	27260156	PATU8902	viability	TACCTGTGATCTCATGCTGCCGG	SRL	ENSG00000185739	0.012438646980832524	[928]	[1247,2065,453,1714]	0	hSpCas9	negative selection	8183602
4242004	4242027	16	+	27260156	PATU8902	viability	TACCTGCTTGTCCTGAGAACAGG	SRL	ENSG00000185739	-0.3500706628221356	[1046]	[1467,504,1192,1413]	-4	hSpCas9	negative selection	8183603
4204532	4204555	16	-	27260156	PANC1	viability	AAGCCATCCGATGACTACTCTGG	SRL	ENSG00000185739	-0.20195151032861516	[552]	[468,374,487,319]	-3	hSpCas9	negative selection	8240597
4204583	4204606	16	+	27260156	PANC1	viability	ATGTGGGAGCGGTCCCTCAATGG	SRL	ENSG00000185739	0.2424932372494481	[509]	[575,599,578,352]	4	hSpCas9	negative selection	8240598
4242055	4242078	16	-	27260156	PANC1	viability	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	-0.2060043381320225	[362]	[243,245,301,278]	-3	hSpCas9	negative selection	8240599
4203182	4203205	16	-	27260156	PANC1	viability	CCTACAAGTACAATGAGCTCCGG	SRL	ENSG00000185739	-0.3195163083104469	[494]	[419,216,378,317]	-5	hSpCas9	negative selection	8304852
4203163	4203186	16	+	27260156	PANC1	viability	TACCTGTGATCTCATGCTGCCGG	SRL	ENSG00000185739	-0.15220633283224294	[928]	[576,903,766,662]	-2	hSpCas9	negative selection	8304853
4242004	4242027	16	+	27260156	PANC1	viability	TACCTGCTTGTCCTGAGAACAGG	SRL	ENSG00000185739	0.046465647276844546	[1046]	[1051,902,1168,620]	0	hSpCas9	negative selection	8304854
4204532	4204555	16	-	27260156	PANC0813	viability	AAGCCATCCGATGACTACTCTGG	SRL	ENSG00000185739	0.02875826244672583	[552]	[593,816,626,607]	0	hSpCas9	negative selection	8361848
4204583	4204606	16	+	27260156	PANC0813	viability	ATGTGGGAGCGGTCCCTCAATGG	SRL	ENSG00000185739	-0.1661018728191047	[509]	[480,650,403,589]	-3	hSpCas9	negative selection	8361849
4242055	4242078	16	-	27260156	PANC0813	viability	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	0.06467615151689232	[362]	[429,349,604,399]	1	hSpCas9	negative selection	8361850
4203182	4203205	16	-	27260156	PANC0813	viability	CCTACAAGTACAATGAGCTCCGG	SRL	ENSG00000185739	-0.2101591817331543	[494]	[500,721,362,426]	-3	hSpCas9	negative selection	8426103
4203163	4203186	16	+	27260156	PANC0813	viability	TACCTGTGATCTCATGCTGCCGG	SRL	ENSG00000185739	-0.004400071655479509	[928]	[872,1238,1076,1137]	0	hSpCas9	negative selection	8426104
4242004	4242027	16	+	27260156	PANC0813	viability	TACCTGCTTGTCCTGAGAACAGG	SRL	ENSG00000185739	-0.44431947515229575	[1046]	[884,775,825,1112]	-6	hSpCas9	negative selection	8426105
4204532	4204555	16	-	27260156	RDES	viability	AAGCCATCCGATGACTACTCTGG	SRL	ENSG00000185739	-0.32021489290936894	[552]	[520,355,454,732]	-5	hSpCas9	negative selection	8483099
4204583	4204606	16	+	27260156	RDES	viability	ATGTGGGAGCGGTCCCTCAATGG	SRL	ENSG00000185739	0.011172042786270972	[509]	[449,589,674,678]	0	hSpCas9	negative selection	8483100
4242055	4242078	16	-	27260156	RDES	viability	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	-0.23382067163884418	[362]	[283,313,300,558]	-4	hSpCas9	negative selection	8483101
4203182	4203205	16	-	27260156	RDES	viability	CCTACAAGTACAATGAGCTCCGG	SRL	ENSG00000185739	-0.35006984286258275	[494]	[390,376,481,559]	-5	hSpCas9	negative selection	8547354
4203163	4203186	16	+	27260156	RDES	viability	TACCTGTGATCTCATGCTGCCGG	SRL	ENSG00000185739	-0.13345199307486144	[928]	[757,879,1113,1212]	-2	hSpCas9	negative selection	8547355
4242004	4242027	16	+	27260156	RDES	viability	TACCTGCTTGTCCTGAGAACAGG	SRL	ENSG00000185739	-0.12275926320854458	[1046]	[1354,971,928,1070]	-2	hSpCas9	negative selection	8547356
4204532	4204555	16	-	27260156	PC3	viability	AAGCCATCCGATGACTACTCTGG	SRL	ENSG00000185739	0.18067945640769653	[552]	[344,501,931,928]	4	hSpCas9	negative selection	8604350
4204583	4204606	16	+	27260156	PC3	viability	ATGTGGGAGCGGTCCCTCAATGG	SRL	ENSG00000185739	0.22713828970824446	[509]	[377,463,929,791]	5	hSpCas9	negative selection	8604351
4242055	4242078	16	-	27260156	PC3	viability	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	0.061805402705564005	[362]	[246,331,808,309]	1	hSpCas9	negative selection	8604352
4203182	4203205	16	-	27260156	PC3	viability	CCTACAAGTACAATGAGCTCCGG	SRL	ENSG00000185739	-0.3731833515202452	[494]	[296,350,527,398]	-7	hSpCas9	negative selection	8668605
4203163	4203186	16	+	27260156	PC3	viability	TACCTGTGATCTCATGCTGCCGG	SRL	ENSG00000185739	-0.3085085854777665	[928]	[321,647,1236,1131]	-6	hSpCas9	negative selection	8668606
4242004	4242027	16	+	27260156	PC3	viability	TACCTGCTTGTCCTGAGAACAGG	SRL	ENSG00000185739	-0.4211808357075786	[1046]	[504,590,1509,853]	-7	hSpCas9	negative selection	8668607
4204532	4204555	16	-	27260156	PATU8988T	viability	AAGCCATCCGATGACTACTCTGG	SRL	ENSG00000185739	0.22428304972895421	[552]	[630,564,373,950]	4	hSpCas9	negative selection	8725601
4204583	4204606	16	+	27260156	PATU8988T	viability	ATGTGGGAGCGGTCCCTCAATGG	SRL	ENSG00000185739	0.14962582693549653	[509]	[514,656,545,472]	2	hSpCas9	negative selection	8725602
4242055	4242078	16	-	27260156	PATU8988T	viability	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	-0.17471427222335983	[362]	[380,355,305,194]	-3	hSpCas9	negative selection	8725603
4203182	4203205	16	-	27260156	PATU8988T	viability	CCTACAAGTACAATGAGCTCCGG	SRL	ENSG00000185739	-0.07766672832408719	[494]	[395,416,622,363]	-1	hSpCas9	negative selection	8789856
4203163	4203186	16	+	27260156	PATU8988T	viability	TACCTGTGATCTCATGCTGCCGG	SRL	ENSG00000185739	-0.2863989375758913	[928]	[695,744,615,902]	-5	hSpCas9	negative selection	8789857
4242004	4242027	16	+	27260156	PATU8988T	viability	TACCTGCTTGTCCTGAGAACAGG	SRL	ENSG00000185739	-0.2886424401072255	[1046]	[513,847,911,1057]	-5	hSpCas9	negative selection	8789858
4204532	4204555	16	-	27260156	T47D	viability	AAGCCATCCGATGACTACTCTGG	SRL	ENSG00000185739	-0.3574478180164123	[552]	[388,520,487,614]	-6	hSpCas9	negative selection	8846852
4204583	4204606	16	+	27260156	T47D	viability	ATGTGGGAGCGGTCCCTCAATGG	SRL	ENSG00000185739	-0.01599485190196212	[509]	[546,518,602,689]	0	hSpCas9	negative selection	8846853
4242055	4242078	16	-	27260156	T47D	viability	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	-0.22170982197161798	[362]	[376,290,359,430]	-5	hSpCas9	negative selection	8846854
4203182	4203205	16	-	27260156	T47D	viability	CCTACAAGTACAATGAGCTCCGG	SRL	ENSG00000185739	-0.5340579196999431	[494]	[436,404,274,479]	-8	hSpCas9	negative selection	8911107
4203163	4203186	16	+	27260156	T47D	viability	TACCTGTGATCTCATGCTGCCGG	SRL	ENSG00000185739	-0.22016403483538838	[928]	[888,918,937,971]	-5	hSpCas9	negative selection	8911108
4242004	4242027	16	+	27260156	T47D	viability	TACCTGCTTGTCCTGAGAACAGG	SRL	ENSG00000185739	-0.30649417757566133	[1046]	[950,1011,978,1000]	-6	hSpCas9	negative selection	8911109
4204532	4204555	16	-	27260156	SU8686	viability	AAGCCATCCGATGACTACTCTGG	SRL	ENSG00000185739	0.17980280599853102	[552]	[638,508,538,837]	3	hSpCas9	negative selection	8968103
4204583	4204606	16	+	27260156	SU8686	viability	ATGTGGGAGCGGTCCCTCAATGG	SRL	ENSG00000185739	0.06661487295392061	[509]	[558,466,606,479]	1	hSpCas9	negative selection	8968104
4242055	4242078	16	-	27260156	SU8686	viability	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	-0.1536870755199536	[362]	[318,283,363,332]	-3	hSpCas9	negative selection	8968105
4203182	4203205	16	-	27260156	SU8686	viability	CCTACAAGTACAATGAGCTCCGG	SRL	ENSG00000185739	0.12072087064547109	[494]	[502,460,471,738]	2	hSpCas9	negative selection	9032358
4203163	4203186	16	+	27260156	SU8686	viability	TACCTGTGATCTCATGCTGCCGG	SRL	ENSG00000185739	-0.08118811503462564	[928]	[681,643,1109,1141]	-1	hSpCas9	negative selection	9032359
4242004	4242027	16	+	27260156	SU8686	viability	TACCTGCTTGTCCTGAGAACAGG	SRL	ENSG00000185739	-0.16500866763269162	[1046]	[877,778,1026,1061]	-3	hSpCas9	negative selection	9032360
4204532	4204555	16	-	27260156	SKES1	viability	AAGCCATCCGATGACTACTCTGG	SRL	ENSG00000185739	0.0114809545294709	[552]	[600,579,571,482]	0	hSpCas9	negative selection	9089354
4204583	4204606	16	+	27260156	SKES1	viability	ATGTGGGAGCGGTCCCTCAATGG	SRL	ENSG00000185739	0.20423639824148693	[509]	[594,740,582,454]	4	hSpCas9	negative selection	9089355
4242055	4242078	16	-	27260156	SKES1	viability	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	-0.014299433320230703	[362]	[334,354,290,436]	0	hSpCas9	negative selection	9089356
4203182	4203205	16	-	27260156	SKES1	viability	CCTACAAGTACAATGAGCTCCGG	SRL	ENSG00000185739	-0.17841414278034337	[494]	[426,424,450,434]	-4	hSpCas9	negative selection	9153609
4203163	4203186	16	+	27260156	SKES1	viability	TACCTGTGATCTCATGCTGCCGG	SRL	ENSG00000185739	-0.16774757149746278	[928]	[1040,1043,768,529]	-4	hSpCas9	negative selection	9153610
4242004	4242027	16	+	27260156	SKES1	viability	TACCTGCTTGTCCTGAGAACAGG	SRL	ENSG00000185739	-0.30461021226220975	[1046]	[1062,945,694,727]	-6	hSpCas9	negative selection	9153611
4204532	4204555	16	-	27260156	TOV112D	viability	AAGCCATCCGATGACTACTCTGG	SRL	ENSG00000185739	0.11796080120619415	[552]	[560,881,353,669]	2	hSpCas9	negative selection	9210605
4204583	4204606	16	+	27260156	TOV112D	viability	ATGTGGGAGCGGTCCCTCAATGG	SRL	ENSG00000185739	0.0362424331493018	[509]	[493,493,411,679]	0	hSpCas9	negative selection	9210606
4242055	4242078	16	-	27260156	TOV112D	viability	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	0.4910068337912184	[362]	[373,650,423,613]	8	hSpCas9	negative selection	9210607
4203182	4203205	16	-	27260156	TOV112D	viability	CCTACAAGTACAATGAGCTCCGG	SRL	ENSG00000185739	-0.42881900957350283	[494]	[377,337,420,329]	-7	hSpCas9	negative selection	9274860
4203163	4203186	16	+	27260156	TOV112D	viability	TACCTGTGATCTCATGCTGCCGG	SRL	ENSG00000185739	-0.21610538824653625	[928]	[613,1026,707,890]	-4	hSpCas9	negative selection	9274861
4242004	4242027	16	+	27260156	TOV112D	viability	TACCTGCTTGTCCTGAGAACAGG	SRL	ENSG00000185739	-0.5469312389845118	[1046]	[712,928,618,661]	-8	hSpCas9	negative selection	9274862
4204532	4204555	16	-	27260156	TC71	viability	AAGCCATCCGATGACTACTCTGG	SRL	ENSG00000185739	-0.1488606418232631	[552]	[481,494,533,634]	-4	hSpCas9	negative selection	9331856
4204583	4204606	16	+	27260156	TC71	viability	ATGTGGGAGCGGTCCCTCAATGG	SRL	ENSG00000185739	0.06735697651983312	[509]	[568,501,554,671]	1	hSpCas9	negative selection	9331857
4242055	4242078	16	-	27260156	TC71	viability	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	-0.0911161190589937	[362]	[355,435,338,328]	-2	hSpCas9	negative selection	9331858
4203182	4203205	16	-	27260156	TC71	viability	CCTACAAGTACAATGAGCTCCGG	SRL	ENSG00000185739	-0.20397285029012524	[494]	[421,450,496,472]	-5	hSpCas9	negative selection	9396111
4203163	4203186	16	+	27260156	TC71	viability	TACCTGTGATCTCATGCTGCCGG	SRL	ENSG00000185739	-0.23746590198077644	[928]	[849,837,761,936]	-6	hSpCas9	negative selection	9396112
4242004	4242027	16	+	27260156	TC71	viability	TACCTGCTTGTCCTGAGAACAGG	SRL	ENSG00000185739	-0.215728946596893	[1046]	[916,941,883,1136]	-5	hSpCas9	negative selection	9396113
4204532	4204555	16	-	27260156	TC32	viability	AAGCCATCCGATGACTACTCTGG	SRL	ENSG00000185739	-0.24104759450728594	[552]	[466,296,627,422]	-4	hSpCas9	negative selection	9453107
4204583	4204606	16	+	27260156	TC32	viability	ATGTGGGAGCGGTCCCTCAATGG	SRL	ENSG00000185739	0.13524598115184494	[509]	[462,442,550,667]	2	hSpCas9	negative selection	9453108
4242055	4242078	16	-	27260156	TC32	viability	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	0.0363223042341736	[362]	[273,241,526,421]	0	hSpCas9	negative selection	9453109
4203182	4203205	16	-	27260156	TC32	viability	CCTACAAGTACAATGAGCTCCGG	SRL	ENSG00000185739	-0.14128596543160302	[494]	[386,390,514,397]	-3	hSpCas9	negative selection	9517362
4203163	4203186	16	+	27260156	TC32	viability	TACCTGTGATCTCATGCTGCCGG	SRL	ENSG00000185739	-0.18730141491145447	[928]	[792,553,809,958]	-3	hSpCas9	negative selection	9517363
4242004	4242027	16	+	27260156	TC32	viability	TACCTGCTTGTCCTGAGAACAGG	SRL	ENSG00000185739	-0.3286153484023646	[1046]	[580,622,1176,866]	-6	hSpCas9	negative selection	9517364
4192723	4192746	16	+	27869803	HPAFII	viability after 27 days	CTCTGTGACATTGATGAGAGGGG	SRL	ENSG00000185739	-0.012876477700232813	[629]	[420,250,NaN]	0	hSpCas9	negative selection	9557103
4195552	4195575	16	-	27869803	HPAFII	viability after 27 days	AACCGCAAGCAGCAAGAAAGAGG	SRL	ENSG00000185739	-0.3063924398773622	[469]	[159,232,NaN]	-2	hSpCas9	negative selection	9557104
4197872	4197895	16	+	27869803	HPAFII	viability after 27 days	CGGTCCCAGGAACAGTACCATGG	SRL	ENSG00000185739	0.2573182853992253	[478]	[246,345,NaN]	2	hSpCas9	negative selection	9557105
4204529	4204552	16	+	27869803	HPAFII	viability after 27 days	TTACCAGAGTAGTCATCGGATGG	SRL	ENSG00000185739	-1.2961059800001293	[168]	[57,17,NaN]	-7	hSpCas9	negative selection	9557106
4207168	4207191	16	+	27869803	HPAFII	viability after 27 days	TCTTCGGACTCCTCTTCGGAGGG	SRL	ENSG00000185739	0.9164015302826967	[105]	[126,86,NaN]	7	hSpCas9	negative selection	9557107
4207363	4207386	16	-	27869803	HPAFII	viability after 27 days	AGTGAGGGCACCGAGGACCAGGG	SRL	ENSG00000185739	-2.6974372299795686	[165]	[19,7,NaN]	-8	hSpCas9	negative selection	9557108
4192723	4192746	16	+	27869803	HPAFII	viability after 15 days	CTCTGTGACATTGATGAGAGGGG	SRL	ENSG00000185739	0.020765066226369866	[629]	[816,605,NaN]	0	hSpCas9	negative selection	9639552
4195552	4195575	16	-	27869803	HPAFII	viability after 15 days	AACCGCAAGCAGCAAGAAAGAGG	SRL	ENSG00000185739	-0.12697226441849951	[469]	[641,350,NaN]	-1	hSpCas9	negative selection	9639553
4197872	4197895	16	+	27869803	HPAFII	viability after 15 days	CGGTCCCAGGAACAGTACCATGG	SRL	ENSG00000185739	-0.013052951356723907	[478]	[429,559,NaN]	0	hSpCas9	negative selection	9639554
4204529	4204552	16	+	27869803	HPAFII	viability after 15 days	TTACCAGAGTAGTCATCGGATGG	SRL	ENSG00000185739	-1.3132494991437937	[168]	[143,28,NaN]	-8	hSpCas9	negative selection	9639555
4207168	4207191	16	+	27869803	HPAFII	viability after 15 days	TCTTCGGACTCCTCTTCGGAGGG	SRL	ENSG00000185739	0.6442252764765544	[105]	[153,192,NaN]	7	hSpCas9	negative selection	9639556
4207363	4207386	16	-	27869803	HPAFII	viability after 15 days	AGTGAGGGCACCGAGGACCAGGG	SRL	ENSG00000185739	-2.1433235173133136	[165]	[40,39,NaN]	-9	hSpCas9	negative selection	9639557
4192723	4192746	16	+	27869803	ASPC1	viability after 36 days	CTCTGTGACATTGATGAGAGGGG	SRL	ENSG00000185739	0.1304468304784563	[1273]	[483,372,573]	1	hSpCas9	negative selection	9722001
4195552	4195575	16	-	27869803	ASPC1	viability after 36 days	AACCGCAAGCAGCAAGAAAGAGG	SRL	ENSG00000185739	0.12510099998488233	[1182]	[728,476,228]	1	hSpCas9	negative selection	9722002
4197872	4197895	16	+	27869803	ASPC1	viability after 36 days	CGGTCCCAGGAACAGTACCATGG	SRL	ENSG00000185739	0.3251117920384723	[941]	[631,153,457]	3	hSpCas9	negative selection	9722003
4204529	4204552	16	+	27869803	ASPC1	viability after 36 days	TTACCAGAGTAGTCATCGGATGG	SRL	ENSG00000185739	-0.18727096139339527	[459]	[182,251,21]	-2	hSpCas9	negative selection	9722004
4207168	4207191	16	+	27869803	ASPC1	viability after 36 days	TCTTCGGACTCCTCTTCGGAGGG	SRL	ENSG00000185739	0.48550258412820435	[219]	[56,66,173]	5	hSpCas9	negative selection	9722005
4207363	4207386	16	-	27869803	ASPC1	viability after 36 days	AGTGAGGGCACCGAGGACCAGGG	SRL	ENSG00000185739	0.04148741616398555	[341]	[29,119,188]	0	hSpCas9	negative selection	9722006
4192723	4192746	16	+	27869803	PATU8988S	viability after 35 days	CTCTGTGACATTGATGAGAGGGG	SRL	ENSG00000185739	0.5946709835081685	[1148]	[622,774,NaN]	6	hSpCas9	negative selection	9804450
4195552	4195575	16	-	27869803	PATU8988S	viability after 35 days	AACCGCAAGCAGCAAGAAAGAGG	SRL	ENSG00000185739	0.5577666522744131	[1009]	[717,478,NaN]	6	hSpCas9	negative selection	9804451
4197872	4197895	16	+	27869803	PATU8988S	viability after 35 days	CGGTCCCAGGAACAGTACCATGG	SRL	ENSG00000185739	-0.2646033534096106	[975]	[420,232,NaN]	-3	hSpCas9	negative selection	9804452
4204529	4204552	16	+	27869803	PATU8988S	viability after 35 days	TTACCAGAGTAGTCATCGGATGG	SRL	ENSG00000185739	-1.2343896188869004	[373]	[72,54,NaN]	-8	hSpCas9	negative selection	9804453
4207168	4207191	16	+	27869803	PATU8988S	viability after 35 days	TCTTCGGACTCCTCTTCGGAGGG	SRL	ENSG00000185739	0.37732335810154416	[261]	[164,108,NaN]	4	hSpCas9	negative selection	9804454
4207363	4207386	16	-	27869803	PATU8988S	viability after 35 days	AGTGAGGGCACCGAGGACCAGGG	SRL	ENSG00000185739	-0.6775586246915416	[352]	[39,137,NaN]	-6	hSpCas9	negative selection	9804455
4192723	4192746	16	+	27869803	PATU8988S	viability after 31 days	CTCTGTGACATTGATGAGAGGGG	SRL	ENSG00000185739	0.5829028850844569	[1148]	[559,846,NaN]	7	hSpCas9	negative selection	9886899
4195552	4195575	16	-	27869803	PATU8988S	viability after 31 days	AACCGCAAGCAGCAAGAAAGAGG	SRL	ENSG00000185739	0.7253129643123157	[1009]	[755,550,NaN]	8	hSpCas9	negative selection	9886900
4197872	4197895	16	+	27869803	PATU8988S	viability after 31 days	CGGTCCCAGGAACAGTACCATGG	SRL	ENSG00000185739	-0.17451946045789224	[975]	[500,145,NaN]	-2	hSpCas9	negative selection	9886901
4204529	4204552	16	+	27869803	PATU8988S	viability after 31 days	TTACCAGAGTAGTCATCGGATGG	SRL	ENSG00000185739	-1.2367743887493856	[373]	[57,69,NaN]	-8	hSpCas9	negative selection	9886902
4207168	4207191	16	+	27869803	PATU8988S	viability after 31 days	TCTTCGGACTCCTCTTCGGAGGG	SRL	ENSG00000185739	0.5620807299502373	[261]	[155,151,NaN]	6	hSpCas9	negative selection	9886903
4207363	4207386	16	-	27869803	PATU8988S	viability after 31 days	AGTGAGGGCACCGAGGACCAGGG	SRL	ENSG00000185739	-0.6665896718527072	[352]	[67,114,NaN]	-6	hSpCas9	negative selection	9886904
4192723	4192746	16	+	27869803	HPAFII	viability after 35 days	CTCTGTGACATTGATGAGAGGGG	SRL	ENSG00000185739	0.10911213572160205	[629]	[327,361,NaN]	0	hSpCas9	negative selection	9969348
4195552	4195575	16	-	27869803	HPAFII	viability after 35 days	AACCGCAAGCAGCAAGAAAGAGG	SRL	ENSG00000185739	-0.3776694907365449	[469]	[97,278,NaN]	-2	hSpCas9	negative selection	9969349
4197872	4197895	16	+	27869803	HPAFII	viability after 35 days	CGGTCCCAGGAACAGTACCATGG	SRL	ENSG00000185739	0.062191654638301896	[478]	[128,392,NaN]	0	hSpCas9	negative selection	9969350
4204529	4204552	16	+	27869803	HPAFII	viability after 35 days	TTACCAGAGTAGTCATCGGATGG	SRL	ENSG00000185739	-1.3234668357637567	[168]	[52,12,NaN]	-6	hSpCas9	negative selection	9969351
4207168	4207191	16	+	27869803	HPAFII	viability after 35 days	TCTTCGGACTCCTCTTCGGAGGG	SRL	ENSG00000185739	0.9307802651000566	[105]	[106,96,NaN]	6	hSpCas9	negative selection	9969352
4207363	4207386	16	-	27869803	HPAFII	viability after 35 days	AGTGAGGGCACCGAGGACCAGGG	SRL	ENSG00000185739	-4.157986755180446	[165]	[7,0,NaN]	-9	hSpCas9	negative selection	9969353
4192723	4192746	16	+	27869803	HPAFII	viability after 31 days	CTCTGTGACATTGATGAGAGGGG	SRL	ENSG00000185739	0.24902195934203464	[629]	[412,427,NaN]	1	hSpCas9	negative selection	10051797
4195552	4195575	16	-	27869803	HPAFII	viability after 31 days	AACCGCAAGCAGCAAGAAAGAGG	SRL	ENSG00000185739	-0.2832575636679068	[469]	[199,234,NaN]	-2	hSpCas9	negative selection	10051798
4197872	4197895	16	+	27869803	HPAFII	viability after 31 days	CGGTCCCAGGAACAGTACCATGG	SRL	ENSG00000185739	0.39886952635076156	[478]	[285,428,NaN]	3	hSpCas9	negative selection	10051799
4204529	4204552	16	+	27869803	HPAFII	viability after 31 days	TTACCAGAGTAGTCATCGGATGG	SRL	ENSG00000185739	-1.9319196628158024	[168]	[43,3,NaN]	-8	hSpCas9	negative selection	10051800
4207168	4207191	16	+	27869803	HPAFII	viability after 31 days	TCTTCGGACTCCTCTTCGGAGGG	SRL	ENSG00000185739	0.8088599909723453	[105]	[108,98,NaN]	6	hSpCas9	negative selection	10051801
4207363	4207386	16	-	27869803	HPAFII	viability after 31 days	AGTGAGGGCACCGAGGACCAGGG	SRL	ENSG00000185739	-1.6709512486166334	[165]	[34,22,NaN]	-7	hSpCas9	negative selection	10051802
4195752	4195775	16	+	28162770	P31FUJ	viability	GAGGACCGTGAACTCAGAGGTGG	SRL	ENSG00000185739	-0.9246799090520468	[125]	[77]	-6	hSpCas9	negative selection	10242977
4195721	4195744	16	-	28162770	P31FUJ	viability	GCCTAAGCTGAAAACCATCGAGG	SRL	ENSG00000185739	0.67473374796665	[297]	[558]	7	hSpCas9	negative selection	10242978
4197817	4197840	16	+	28162770	P31FUJ	viability	GAGTATTTTCCAGCCCAAGGAGG	SRL	ENSG00000185739	-0.14321341020168132	[358]	[381]	-1	hSpCas9	negative selection	10242979
4204626	4204649	16	-	28162770	P31FUJ	viability	GCTTCTCTCCACAGAAGAGACGG	SRL	ENSG00000185739	0.5111838174296	[122]	[205]	6	hSpCas9	negative selection	10242980
4204557	4204580	16	-	28162770	P31FUJ	viability	GAAGACCCTCATGCTGAATGAGG	SRL	ENSG00000185739	0.3153235281264063	[237]	[347]	3	hSpCas9	negative selection	10242981
4197826	4197849	16	-	28162770	P31FUJ	viability	GATAAACTACCTCCTTGGGCTGG	SRL	ENSG00000185739	0.4720000663127807	[126]	[206]	5	hSpCas9	negative selection	10242982
4242055	4242078	16	-	28162770	P31FUJ	viability	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	-0.168261952219668	[152]	[159]	-2	hSpCas9	negative selection	10242983
4204572	4204595	16	+	28162770	P31FUJ	viability	GGGTCTTCTCGATGTGGGAGCGG	SRL	ENSG00000185739	0.2404499088097607	[84]	[117]	2	hSpCas9	negative selection	10242984
4197889	4197912	16	-	28162770	P31FUJ	viability	AGAGATTACCTCCAAGCCCATGG	SRL	ENSG00000185739	0.3120031698347947	[339]	[495]	3	hSpCas9	negative selection	10242985
4197873	4197896	16	+	28162770	P31FUJ	viability	GGTCCCAGGAACAGTACCATGGG	SRL	ENSG00000185739	-0.18683635046219815	[555]	[573]	-2	hSpCas9	negative selection	10242986
4195752	4195775	16	+	28162770	TF1	viability	GAGGACCGTGAACTCAGAGGTGG	SRL	ENSG00000185739	NaN	[NaN]	[112]	1	hSpCas9	negative selection	10412343
4195721	4195744	16	-	28162770	TF1	viability	GCCTAAGCTGAAAACCATCGAGG	SRL	ENSG00000185739	NaN	[NaN]	[299]	1	hSpCas9	negative selection	10412344
4197817	4197840	16	+	28162770	TF1	viability	GAGTATTTTCCAGCCCAAGGAGG	SRL	ENSG00000185739	NaN	[NaN]	[389]	1	hSpCas9	negative selection	10412345
4204626	4204649	16	-	28162770	TF1	viability	GCTTCTCTCCACAGAAGAGACGG	SRL	ENSG00000185739	NaN	[NaN]	[255]	1	hSpCas9	negative selection	10412346
4204557	4204580	16	-	28162770	TF1	viability	GAAGACCCTCATGCTGAATGAGG	SRL	ENSG00000185739	NaN	[NaN]	[233]	1	hSpCas9	negative selection	10412347
4197826	4197849	16	-	28162770	TF1	viability	GATAAACTACCTCCTTGGGCTGG	SRL	ENSG00000185739	NaN	[NaN]	[298]	1	hSpCas9	negative selection	10412348
4242055	4242078	16	-	28162770	TF1	viability	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	NaN	[NaN]	[65]	1	hSpCas9	negative selection	10412349
4204572	4204595	16	+	28162770	TF1	viability	GGGTCTTCTCGATGTGGGAGCGG	SRL	ENSG00000185739	NaN	[NaN]	[76]	1	hSpCas9	negative selection	10412350
4197889	4197912	16	-	28162770	TF1	viability	AGAGATTACCTCCAAGCCCATGG	SRL	ENSG00000185739	NaN	[NaN]	[299]	1	hSpCas9	negative selection	10412351
4197873	4197896	16	+	28162770	TF1	viability	GGTCCCAGGAACAGTACCATGGG	SRL	ENSG00000185739	NaN	[NaN]	[477]	1	hSpCas9	negative selection	10412352
4195752	4195775	16	+	28162770	SKM1	viability	GAGGACCGTGAACTCAGAGGTGG	SRL	ENSG00000185739	-1.9842731269208824	[46]	[20]	-8	hSpCas9	negative selection	10581709
4195721	4195744	16	-	28162770	SKM1	viability	GCCTAAGCTGAAAACCATCGAGG	SRL	ENSG00000185739	-0.39066238641406126	[65]	[88]	-3	hSpCas9	negative selection	10581710
4197817	4197840	16	+	28162770	SKM1	viability	GAGTATTTTCCAGCCCAAGGAGG	SRL	ENSG00000185739	0.2483876298693924	[69]	[146]	2	hSpCas9	negative selection	10581711
4204626	4204649	16	-	28162770	SKM1	viability	GCTTCTCTCCACAGAAGAGACGG	SRL	ENSG00000185739	-0.943307994244139	[61]	[56]	-6	hSpCas9	negative selection	10581712
4204557	4204580	16	-	28162770	SKM1	viability	GAAGACCCTCATGCTGAATGAGG	SRL	ENSG00000185739	0.417668714746278	[82]	[195]	4	hSpCas9	negative selection	10581713
4197826	4197849	16	-	28162770	SKM1	viability	GATAAACTACCTCCTTGGGCTGG	SRL	ENSG00000185739	0.7629608026991506	[43]	[131]	7	hSpCas9	negative selection	10581714
4242055	4242078	16	-	28162770	SKM1	viability	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	-0.4320551797059924	[28]	[37]	-4	hSpCas9	negative selection	10581715
4204572	4204595	16	+	28162770	SKM1	viability	GGGTCTTCTCGATGTGGGAGCGG	SRL	ENSG00000185739	-0.8220016980220057	[28]	[28]	-6	hSpCas9	negative selection	10581716
4197889	4197912	16	-	28162770	SKM1	viability	AGAGATTACCTCCAAGCCCATGG	SRL	ENSG00000185739	-0.6066126644233201	[117]	[136]	-5	hSpCas9	negative selection	10581717
4197873	4197896	16	+	28162770	SKM1	viability	GGTCCCAGGAACAGTACCATGGG	SRL	ENSG00000185739	-0.22253962760573454	[164]	[249]	-2	hSpCas9	negative selection	10581718
4195752	4195775	16	+	28162770	SKM1	viability	GAGGACCGTGAACTCAGAGGTGG	SRL	ENSG00000185739	-1.9842731269208824	[46]	[20]	-8	hSpCas9	negative selection	10751075
4195721	4195744	16	-	28162770	SKM1	viability	GCCTAAGCTGAAAACCATCGAGG	SRL	ENSG00000185739	-0.39066238641406126	[65]	[88]	-3	hSpCas9	negative selection	10751076
4197817	4197840	16	+	28162770	SKM1	viability	GAGTATTTTCCAGCCCAAGGAGG	SRL	ENSG00000185739	0.2483876298693924	[69]	[146]	2	hSpCas9	negative selection	10751077
4204626	4204649	16	-	28162770	SKM1	viability	GCTTCTCTCCACAGAAGAGACGG	SRL	ENSG00000185739	-0.943307994244139	[61]	[56]	-6	hSpCas9	negative selection	10751078
4204557	4204580	16	-	28162770	SKM1	viability	GAAGACCCTCATGCTGAATGAGG	SRL	ENSG00000185739	0.417668714746278	[82]	[195]	4	hSpCas9	negative selection	10751079
4197826	4197849	16	-	28162770	SKM1	viability	GATAAACTACCTCCTTGGGCTGG	SRL	ENSG00000185739	0.7629608026991506	[43]	[131]	7	hSpCas9	negative selection	10751080
4242055	4242078	16	-	28162770	SKM1	viability	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	-0.4320551797059924	[28]	[37]	-4	hSpCas9	negative selection	10751081
4204572	4204595	16	+	28162770	SKM1	viability	GGGTCTTCTCGATGTGGGAGCGG	SRL	ENSG00000185739	-0.8220016980220057	[28]	[28]	-6	hSpCas9	negative selection	10751082
4197889	4197912	16	-	28162770	SKM1	viability	AGAGATTACCTCCAAGCCCATGG	SRL	ENSG00000185739	-0.6066126644233201	[117]	[136]	-5	hSpCas9	negative selection	10751083
4197873	4197896	16	+	28162770	SKM1	viability	GGTCCCAGGAACAGTACCATGGG	SRL	ENSG00000185739	-0.22253962760573454	[164]	[249]	-2	hSpCas9	negative selection	10751084
4195752	4195775	16	+	28162770	PL21	viability	GAGGACCGTGAACTCAGAGGTGG	SRL	ENSG00000185739	0.7020203737159211	[136]	[96]	6	hSpCas9	negative selection	10920441
4195721	4195744	16	-	28162770	PL21	viability	GCCTAAGCTGAAAACCATCGAGG	SRL	ENSG00000185739	-0.7908152459076732	[158]	[39]	-5	hSpCas9	negative selection	10920442
4197817	4197840	16	+	28162770	PL21	viability	GAGTATTTTCCAGCCCAAGGAGG	SRL	ENSG00000185739	1.0671657492198992	[317]	[289]	8	hSpCas9	negative selection	10920443
4204626	4204649	16	-	28162770	PL21	viability	GCTTCTCTCCACAGAAGAGACGG	SRL	ENSG00000185739	1.0894955508053275	[148]	[137]	8	hSpCas9	negative selection	10920444
4204557	4204580	16	-	28162770	PL21	viability	GAAGACCCTCATGCTGAATGAGG	SRL	ENSG00000185739	-0.1798411484442074	[392]	[150]	-1	hSpCas9	negative selection	10920445
4197826	4197849	16	-	28162770	PL21	viability	GATAAACTACCTCCTTGGGCTGG	SRL	ENSG00000185739	0.9034220823992376	[155]	[126]	7	hSpCas9	negative selection	10920446
4242055	4242078	16	-	28162770	PL21	viability	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	-0.3234223415676929	[114]	[39]	-2	hSpCas9	negative selection	10920447
4204572	4204595	16	+	28162770	PL21	viability	GGGTCTTCTCGATGTGGGAGCGG	SRL	ENSG00000185739	-0.5963269914255476	[65]	[18]	-4	hSpCas9	negative selection	10920448
4197889	4197912	16	-	28162770	PL21	viability	AGAGATTACCTCCAAGCCCATGG	SRL	ENSG00000185739	0.3050261866571551	[304]	[163]	2	hSpCas9	negative selection	10920449
4197873	4197896	16	+	28162770	PL21	viability	GGTCCCAGGAACAGTACCATGGG	SRL	ENSG00000185739	-0.4128372624014325	[519]	[169]	-3	hSpCas9	negative selection	10920450
4195752	4195775	16	+	28162770	P31FUJ	viability	GAGGACCGTGAACTCAGAGGTGG	SRL	ENSG00000185739	-0.9246799090520468	[125]	[77]	-6	hSpCas9	negative selection	11089807
4195721	4195744	16	-	28162770	P31FUJ	viability	GCCTAAGCTGAAAACCATCGAGG	SRL	ENSG00000185739	0.67473374796665	[297]	[558]	7	hSpCas9	negative selection	11089808
4197817	4197840	16	+	28162770	P31FUJ	viability	GAGTATTTTCCAGCCCAAGGAGG	SRL	ENSG00000185739	-0.14321341020168132	[358]	[381]	-1	hSpCas9	negative selection	11089809
4204626	4204649	16	-	28162770	P31FUJ	viability	GCTTCTCTCCACAGAAGAGACGG	SRL	ENSG00000185739	0.5111838174296	[122]	[205]	6	hSpCas9	negative selection	11089810
4204557	4204580	16	-	28162770	P31FUJ	viability	GAAGACCCTCATGCTGAATGAGG	SRL	ENSG00000185739	0.3153235281264063	[237]	[347]	3	hSpCas9	negative selection	11089811
4197826	4197849	16	-	28162770	P31FUJ	viability	GATAAACTACCTCCTTGGGCTGG	SRL	ENSG00000185739	0.4720000663127807	[126]	[206]	5	hSpCas9	negative selection	11089812
4242055	4242078	16	-	28162770	P31FUJ	viability	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	-0.168261952219668	[152]	[159]	-2	hSpCas9	negative selection	11089813
4204572	4204595	16	+	28162770	P31FUJ	viability	GGGTCTTCTCGATGTGGGAGCGG	SRL	ENSG00000185739	0.2404499088097607	[84]	[117]	2	hSpCas9	negative selection	11089814
4197889	4197912	16	-	28162770	P31FUJ	viability	AGAGATTACCTCCAAGCCCATGG	SRL	ENSG00000185739	0.3120031698347947	[339]	[495]	3	hSpCas9	negative selection	11089815
4197873	4197896	16	+	28162770	P31FUJ	viability	GGTCCCAGGAACAGTACCATGGG	SRL	ENSG00000185739	-0.18683635046219815	[555]	[573]	-2	hSpCas9	negative selection	11089816
4195752	4195775	16	+	28162770	OCIAML5	viability	GAGGACCGTGAACTCAGAGGTGG	SRL	ENSG00000185739	-0.2511625262738192	[59]	[90]	-2	hSpCas9	negative selection	11259173
4195721	4195744	16	-	28162770	OCIAML5	viability	GCCTAAGCTGAAAACCATCGAGG	SRL	ENSG00000185739	-0.14049775376327212	[148]	[243]	-1	hSpCas9	negative selection	11259174
4197817	4197840	16	+	28162770	OCIAML5	viability	GAGTATTTTCCAGCCCAAGGAGG	SRL	ENSG00000185739	0.3993082441980573	[175]	[418]	3	hSpCas9	negative selection	11259175
4204626	4204649	16	-	28162770	OCIAML5	viability	GCTTCTCTCCACAGAAGAGACGG	SRL	ENSG00000185739	-1.2721750596902628	[94]	[70]	-6	hSpCas9	negative selection	11259176
4204557	4204580	16	-	28162770	OCIAML5	viability	GAAGACCCTCATGCTGAATGAGG	SRL	ENSG00000185739	0.853312680244376	[156]	[511]	7	hSpCas9	negative selection	11259177
4197826	4197849	16	-	28162770	OCIAML5	viability	GATAAACTACCTCCTTGGGCTGG	SRL	ENSG00000185739	0.6791246734161784	[81]	[236]	6	hSpCas9	negative selection	11259178
4242055	4242078	16	-	28162770	OCIAML5	viability	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	-0.7265356887801382	[76]	[83]	-5	hSpCas9	negative selection	11259179
4204572	4204595	16	+	28162770	OCIAML5	viability	GGGTCTTCTCGATGTGGGAGCGG	SRL	ENSG00000185739	-0.14352938502430845	[81]	[133]	-1	hSpCas9	negative selection	11259180
4197889	4197912	16	-	28162770	OCIAML5	viability	AGAGATTACCTCCAAGCCCATGG	SRL	ENSG00000185739	1.40928145834191	[106]	[512]	9	hSpCas9	negative selection	11259181
4197873	4197896	16	+	28162770	OCIAML5	viability	GGTCCCAGGAACAGTACCATGGG	SRL	ENSG00000185739	0.2552101654540786	[284]	[613]	2	hSpCas9	negative selection	11259182
4195752	4195775	16	+	28162770	EOL1	viability	GAGGACCGTGAACTCAGAGGTGG	SRL	ENSG00000185739	-0.21024900646817607	[212]	[96]	-2	hSpCas9	negative selection	11428539
4195721	4195744	16	-	28162770	EOL1	viability	GCCTAAGCTGAAAACCATCGAGG	SRL	ENSG00000185739	-1.1726208874364634	[260]	[60]	-7	hSpCas9	negative selection	11428540
4197817	4197840	16	+	28162770	EOL1	viability	GAGTATTTTCCAGCCCAAGGAGG	SRL	ENSG00000185739	0.5525789941835768	[681]	[526]	5	hSpCas9	negative selection	11428541
4204626	4204649	16	-	28162770	EOL1	viability	GCTTCTCTCCACAGAAGAGACGG	SRL	ENSG00000185739	-1.115609354901448	[254]	[61]	-6	hSpCas9	negative selection	11428542
4204557	4204580	16	-	28162770	EOL1	viability	GAAGACCCTCATGCTGAATGAGG	SRL	ENSG00000185739	-0.1768292488045473	[559]	[260]	-1	hSpCas9	negative selection	11428543
4197826	4197849	16	-	28162770	EOL1	viability	GATAAACTACCTCCTTGGGCTGG	SRL	ENSG00000185739	-0.3492860351157826	[294]	[121]	-3	hSpCas9	negative selection	11428544
4242055	4242078	16	-	28162770	EOL1	viability	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	-0.2978446497659135	[195]	[83]	-2	hSpCas9	negative selection	11428545
4204572	4204595	16	+	28162770	EOL1	viability	GGGTCTTCTCGATGTGGGAGCGG	SRL	ENSG00000185739	0.1085106064131296	[124]	[70]	1	hSpCas9	negative selection	11428546
4197889	4197912	16	-	28162770	EOL1	viability	AGAGATTACCTCCAAGCCCATGG	SRL	ENSG00000185739	-0.038926352404351494	[350]	[179]	0	hSpCas9	negative selection	11428547
4197873	4197896	16	+	28162770	EOL1	viability	GGTCCCAGGAACAGTACCATGGG	SRL	ENSG00000185739	0.018233217111968125	[625]	[333]	0	hSpCas9	negative selection	11428548
4195752	4195775	16	+	28162770	MOLM13	viability	GAGGACCGTGAACTCAGAGGTGG	SRL	ENSG00000185739	0.18637555510312467	[219]	[180]	1	hSpCas9	negative selection	11597905
4195721	4195744	16	-	28162770	MOLM13	viability	GCCTAAGCTGAAAACCATCGAGG	SRL	ENSG00000185739	-0.04812576545908593	[285]	[199]	0	hSpCas9	negative selection	11597906
4197817	4197840	16	+	28162770	MOLM13	viability	GAGTATTTTCCAGCCCAAGGAGG	SRL	ENSG00000185739	1.0435140176863986	[464]	[692]	7	hSpCas9	negative selection	11597907
4204626	4204649	16	-	28162770	MOLM13	viability	GCTTCTCTCCACAGAAGAGACGG	SRL	ENSG00000185739	0.8034924133290179	[209]	[264]	6	hSpCas9	negative selection	11597908
4204557	4204580	16	-	28162770	MOLM13	viability	GAAGACCCTCATGCTGAATGAGG	SRL	ENSG00000185739	1.568228002126594	[478]	[1026]	9	hSpCas9	negative selection	11597909
4197826	4197849	16	-	28162770	MOLM13	viability	GATAAACTACCTCCTTGGGCTGG	SRL	ENSG00000185739	0.4678893815445788	[231]	[231]	3	hSpCas9	negative selection	11597910
4242055	4242078	16	-	28162770	MOLM13	viability	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	0.23469020525154793	[133]	[113]	1	hSpCas9	negative selection	11597911
4204572	4204595	16	+	28162770	MOLM13	viability	GGGTCTTCTCGATGTGGGAGCGG	SRL	ENSG00000185739	0.24318309436988428	[103]	[88]	1	hSpCas9	negative selection	11597912
4197889	4197912	16	-	28162770	MOLM13	viability	AGAGATTACCTCCAAGCCCATGG	SRL	ENSG00000185739	0.3040884825330026	[381]	[340]	2	hSpCas9	negative selection	11597913
4197873	4197896	16	+	28162770	MOLM13	viability	GGTCCCAGGAACAGTACCATGGG	SRL	ENSG00000185739	-0.12052867781279675	[626]	[416]	0	hSpCas9	negative selection	11597914
4195752	4195775	16	+	28162770	HEL	viability	GAGGACCGTGAACTCAGAGGTGG	SRL	ENSG00000185739	0.5708459135185714	[143]	[136]	5	hSpCas9	negative selection	11767271
4195721	4195744	16	-	28162770	HEL	viability	GCCTAAGCTGAAAACCATCGAGG	SRL	ENSG00000185739	-0.0011173577743676943	[224]	[143]	0	hSpCas9	negative selection	11767272
4197817	4197840	16	+	28162770	HEL	viability	GAGTATTTTCCAGCCCAAGGAGG	SRL	ENSG00000185739	0.9287898905591228	[455]	[555]	7	hSpCas9	negative selection	11767273
4204626	4204649	16	-	28162770	HEL	viability	GCTTCTCTCCACAGAAGAGACGG	SRL	ENSG00000185739	0.7341618597639515	[213]	[227]	6	hSpCas9	negative selection	11767274
4204557	4204580	16	-	28162770	HEL	viability	GAAGACCCTCATGCTGAATGAGG	SRL	ENSG00000185739	0.34900762894364656	[379]	[309]	3	hSpCas9	negative selection	11767275
4197826	4197849	16	-	28162770	HEL	viability	GATAAACTACCTCCTTGGGCTGG	SRL	ENSG00000185739	0.7992433176803476	[191]	[213]	7	hSpCas9	negative selection	11767276
4242055	4242078	16	-	28162770	HEL	viability	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	0.4245586619508235	[113]	[97]	3	hSpCas9	negative selection	11767277
4204572	4204595	16	+	28162770	HEL	viability	GGGTCTTCTCGATGTGGGAGCGG	SRL	ENSG00000185739	0.642738832000357	[108]	[108]	5	hSpCas9	negative selection	11767278
4197889	4197912	16	-	28162770	HEL	viability	AGAGATTACCTCCAAGCCCATGG	SRL	ENSG00000185739	-0.14035081167961078	[338]	[196]	-1	hSpCas9	negative selection	11767279
4197873	4197896	16	+	28162770	HEL	viability	GGTCCCAGGAACAGTACCATGGG	SRL	ENSG00000185739	-0.3824984594986658	[518]	[254]	-3	hSpCas9	negative selection	11767280
4195752	4195775	16	+	28162770	MV411	viability	GAGGACCGTGAACTCAGAGGTGG	SRL	ENSG00000185739	-2.0031059108678213	[137]	[28]	-8	hSpCas9	negative selection	11936637
4195721	4195744	16	-	28162770	MV411	viability	GCCTAAGCTGAAAACCATCGAGG	SRL	ENSG00000185739	0.17789661752969832	[169]	[161]	1	hSpCas9	negative selection	11936638
4197817	4197840	16	+	28162770	MV411	viability	GAGTATTTTCCAGCCCAAGGAGG	SRL	ENSG00000185739	0.28515721673193395	[301]	[309]	2	hSpCas9	negative selection	11936639
4204626	4204649	16	-	28162770	MV411	viability	GCTTCTCTCCACAGAAGAGACGG	SRL	ENSG00000185739	0.8938005961680748	[137]	[215]	7	hSpCas9	negative selection	11936640
4204557	4204580	16	-	28162770	MV411	viability	GAAGACCCTCATGCTGAATGAGG	SRL	ENSG00000185739	-0.07449054410458711	[354]	[283]	0	hSpCas9	negative selection	11936641
4197826	4197849	16	-	28162770	MV411	viability	GATAAACTACCTCCTTGGGCTGG	SRL	ENSG00000185739	0.6225823229381064	[164]	[213]	5	hSpCas9	negative selection	11936642
4242055	4242078	16	-	28162770	MV411	viability	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	0.6321014010181001	[107]	[140]	6	hSpCas9	negative selection	11936643
4204572	4204595	16	+	28162770	MV411	viability	GGGTCTTCTCGATGTGGGAGCGG	SRL	ENSG00000185739	1.4631662418382125	[61]	[143]	9	hSpCas9	negative selection	11936644
4197889	4197912	16	-	28162770	MV411	viability	AGAGATTACCTCCAAGCCCATGG	SRL	ENSG00000185739	0.06547475559629945	[345]	[304]	0	hSpCas9	negative selection	11936645
4197873	4197896	16	+	28162770	MV411	viability	GGTCCCAGGAACAGTACCATGGG	SRL	ENSG00000185739	-0.13107407247095426	[428]	[329]	-1	hSpCas9	negative selection	11936646
4195752	4195775	16	+	28162770	MONOMAC1	viability	GAGGACCGTGAACTCAGAGGTGG	SRL	ENSG00000185739	0.7435846058615146	[61]	[118]	7	hSpCas9	negative selection	12106003
4195721	4195744	16	-	28162770	MONOMAC1	viability	GCCTAAGCTGAAAACCATCGAGG	SRL	ENSG00000185739	-0.08482734347352863	[135]	[146]	0	hSpCas9	negative selection	12106004
4197817	4197840	16	+	28162770	MONOMAC1	viability	GAGTATTTTCCAGCCCAAGGAGG	SRL	ENSG00000185739	0.9735941465871528	[226]	[510]	8	hSpCas9	negative selection	12106005
4204626	4204649	16	-	28162770	MONOMAC1	viability	GCTTCTCTCCACAGAAGAGACGG	SRL	ENSG00000185739	0.4115382108835529	[100]	[153]	4	hSpCas9	negative selection	12106006
4204557	4204580	16	-	28162770	MONOMAC1	viability	GAAGACCCTCATGCTGAATGAGG	SRL	ENSG00000185739	0.7619358846803915	[213]	[415]	7	hSpCas9	negative selection	12106007
4197826	4197849	16	-	28162770	MONOMAC1	viability	GATAAACTACCTCCTTGGGCTGG	SRL	ENSG00000185739	-0.08539149123064466	[86]	[93]	0	hSpCas9	negative selection	12106008
4242055	4242078	16	-	28162770	MONOMAC1	viability	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	2.0130772444984575	[58]	[272]	9	hSpCas9	negative selection	12106009
4204572	4204595	16	+	28162770	MONOMAC1	viability	GGGTCTTCTCGATGTGGGAGCGG	SRL	ENSG00000185739	-0.45229390230162836	[73]	[61]	-4	hSpCas9	negative selection	12106010
4197889	4197912	16	-	28162770	MONOMAC1	viability	AGAGATTACCTCCAAGCCCATGG	SRL	ENSG00000185739	1.0376688357157458	[149]	[352]	8	hSpCas9	negative selection	12106011
4197873	4197896	16	+	28162770	MONOMAC1	viability	GGTCCCAGGAACAGTACCATGGG	SRL	ENSG00000185739	-0.06194922402637504	[325]	[357]	0	hSpCas9	negative selection	12106012
4195752	4195775	16	+	28162770	OCIAML2	viability	GAGGACCGTGAACTCAGAGGTGG	SRL	ENSG00000185739	-0.6366397766810904	[22]	[81]	-5	hSpCas9	negative selection	12275369
4195721	4195744	16	-	28162770	OCIAML2	viability	GCCTAAGCTGAAAACCATCGAGG	SRL	ENSG00000185739	-0.0625450866050844	[38]	[206]	0	hSpCas9	negative selection	12275370
4197817	4197840	16	+	28162770	OCIAML2	viability	GAGTATTTTCCAGCCCAAGGAGG	SRL	ENSG00000185739	0.2103017340097172	[62]	[403]	2	hSpCas9	negative selection	12275371
4204626	4204649	16	-	28162770	OCIAML2	viability	GCTTCTCTCCACAGAAGAGACGG	SRL	ENSG00000185739	-0.00030989046212781535	[23]	[132]	0	hSpCas9	negative selection	12275372
4204557	4204580	16	-	28162770	OCIAML2	viability	GAAGACCCTCATGCTGAATGAGG	SRL	ENSG00000185739	0.7083403158031583	[52]	[479]	7	hSpCas9	negative selection	12275373
4197826	4197849	16	-	28162770	OCIAML2	viability	GATAAACTACCTCCTTGGGCTGG	SRL	ENSG00000185739	0.5971147813936729	[25]	[217]	6	hSpCas9	negative selection	12275374
4242055	4242078	16	-	28162770	OCIAML2	viability	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	0.014797001928080755	[14]	[83]	0	hSpCas9	negative selection	12275375
4204572	4204595	16	+	28162770	OCIAML2	viability	GGGTCTTCTCGATGTGGGAGCGG	SRL	ENSG00000185739	-0.5195394257231074	[14]	[57]	-4	hSpCas9	negative selection	12275376
4197889	4197912	16	-	28162770	OCIAML2	viability	AGAGATTACCTCCAAGCCCATGG	SRL	ENSG00000185739	-0.2281361978492038	[55]	[264]	-2	hSpCas9	negative selection	12275377
4197873	4197896	16	+	28162770	OCIAML2	viability	GGTCCCAGGAACAGTACCATGGG	SRL	ENSG00000185739	-0.3682681076124833	[84]	[364]	-3	hSpCas9	negative selection	12275378
4195752	4195775	16	+	28162770	OCIAML3	viability	GAGGACCGTGAACTCAGAGGTGG	SRL	ENSG00000185739	0.086112093437333	[43]	[140]	0	hSpCas9	negative selection	12444735
4195721	4195744	16	-	28162770	OCIAML3	viability	GCCTAAGCTGAAAACCATCGAGG	SRL	ENSG00000185739	0.21998037406588805	[61]	[217]	2	hSpCas9	negative selection	12444736
4197817	4197840	16	+	28162770	OCIAML3	viability	GAGTATTTTCCAGCCCAAGGAGG	SRL	ENSG00000185739	0.3196675598514649	[98]	[372]	3	hSpCas9	negative selection	12444737
4204626	4204649	16	-	28162770	OCIAML3	viability	GCTTCTCTCCACAGAAGAGACGG	SRL	ENSG00000185739	-0.6279549722475009	[42]	[83]	-5	hSpCas9	negative selection	12444738
4204557	4204580	16	-	28162770	OCIAML3	viability	GAAGACCCTCATGCTGAATGAGG	SRL	ENSG00000185739	0.10643207781692898	[75]	[246]	1	hSpCas9	negative selection	12444739
4197826	4197849	16	-	28162770	OCIAML3	viability	GATAAACTACCTCCTTGGGCTGG	SRL	ENSG00000185739	0.18522368081905294	[36]	[126]	1	hSpCas9	negative selection	12444740
4242055	4242078	16	-	28162770	OCIAML3	viability	GGCAGTCACCATGAGGGCGCTGG	SRL	ENSG00000185739	-0.21549601707043342	[29]	[77]	-2	hSpCas9	negative selection	12444741
4204572	4204595	16	+	28162770	OCIAML3	viability	GGGTCTTCTCGATGTGGGAGCGG	SRL	ENSG00000185739	0.44161626940655807	[19]	[81]	4	hSpCas9	negative selection	12444742
4197889	4197912	16	-	28162770	OCIAML3	viability	AGAGATTACCTCCAAGCCCATGG	SRL	ENSG00000185739	-0.2208542220816277	[82]	[214]	-2	hSpCas9	negative selection	12444743
4197873	4197896	16	+	28162770	OCIAML3	viability	GGTCCCAGGAACAGTACCATGGG	SRL	ENSG00000185739	-0.19784815125100885	[124]	[328]	-1	hSpCas9	negative selection	12444744