Gene2Function

Disease Annotation

Gene Info

Species: Human (Homo sapiens)
GeneID: 120892
Symbol: LRRK2
Description: leucine rich repeat kinase 2

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Disease_Term	Source	Rank	Other Values
{Parkinson disease 8}, 607060 (3)	OMIM	high	Genome region : 12q12 OMIM_ID : 607060 OMIM phenotype ID OMIM_ID : 609007 OMIM gene ID
Leprosy	GWAS	high	Pubmed_ID : 20018961 Pubmed_ID : 22019778 Pubmed_ID : 25642632
Crohn's disease	GWAS	high	Pubmed_ID : 17435756 Pubmed_ID : 17447842 Pubmed_ID : 17554261 Pubmed_ID : 17554300 Pubmed_ID : 17684544 Pubmed_ID : 17804789 Pubmed_ID : 18587394 Pubmed_ID : 20570966 Pubmed_ID : 21102463 Pubmed_ID : 22293688 Pubmed_ID : 22412388 Pubmed_ID : 22936669 Pubmed_ID : 23128233 Pubmed_ID : 23266558 Pubmed_ID : 23850713 Pubmed_ID : 26192919 Pubmed_ID : 26891255
Obesity-related traits	GWAS	high	Pubmed_ID : 17658951 Pubmed_ID : 22013104 Pubmed_ID : 23251661
Daytime sleep phenotypes	GWAS	high	Pubmed_ID : 27126917
Parkinson's disease	GWAS	high	Pubmed_ID : 16252231 Pubmed_ID : 17052657 Pubmed_ID : 19915575 Pubmed_ID : 19915576 Pubmed_ID : 20070850 Pubmed_ID : 20711177 Pubmed_ID : 21044948 Pubmed_ID : 21084426 Pubmed_ID : 21292315 Pubmed_ID : 21738487 Pubmed_ID : 21812969 Pubmed_ID : 22438815 Pubmed_ID : 22451204 Pubmed_ID : 23793441 Pubmed_ID : 24511991 Pubmed_ID : 24842889 Pubmed_ID : 25064009 Pubmed_ID : 26227905
Inflammatory bowel disease	GWAS	high	Pubmed_ID : 17068223 Pubmed_ID : 18758464 Pubmed_ID : 23128233 Pubmed_ID : 26192919 Pubmed_ID : 27569725
Pediatric autoimmune diseases	GWAS	high	Pubmed_ID : 26301688
Cerebral amyloid deposition in APOEe4 non-carriers (PET imaging)	GWAS	high	Pubmed_ID : 26252872