| GR00002-A |
32850 |
FBgn0027335 |
l(1)G0003 |
DRSC20000 |
-0.448077584 |
none |
|
no |
|
Lipid storage |
COPI complex is a regulator of lipid homeostasis. |
Beller et al. |
2008 |
19067489 |
Cell line |
Kc167 |
Nuclear to lipid droplet cross-sectional area |
Fluorescence |
np |
Genome-wide |
dsRNA |
B-score |
> 2 OR < -1.7 |
Additional information about a secondary screen with non-overlaping dsRNAs |
GR00002-A |
32850 |
FBgn0027335 |
l(1)G0003 |
DRSC20000 |
-1.294049472 |
none |
|
no |
|
Lipid storage |
COPI complex is a regulator of lipid homeostasis. |
Beller et al. |
2008 |
19067489 |
Cell line |
Kc167 |
Nuclear to lipid droplet cross-sectional area |
Fluorescence |
np |
Genome-wide |
dsRNA |
B-score |
> 2 OR < -1.7 |
Additional information about a secondary screen with non-overlaping dsRNAs |
GR00031-A-1 |
32850 |
|
|
HFA20000 |
0.3 |
none |
|
yes |
|
Cell growth and viability (1) |
Genome-wide RNAi analysis of growth and viability in Drosophila cells. |
Boutros et al. |
2004 |
14764878 |
Cell line |
Kc167 |
Cell number and viability |
Luminescence |
Custom-made (HFA) |
Genome-wide |
dsRNA |
Z-score |
> |
|
GR00031-A-2 |
32850 |
|
|
HFA20000 |
0.1 |
none |
|
no |
|
Cell growth and viability (2) |
Genome-wide RNAi analysis of growth and viability in Drosophila cells. |
Boutros et al. |
2004 |
14764878 |
Cell line |
S2R+ |
Cell number and viability |
Luminescence |
Custom-made (HFA) |
Genome-wide |
dsRNA |
Z-score |
> |
|
GR00040-A-0 |
32850 |
HDC19593 |
|
DRSC20000 |
-1.28 |
Decreased Wnt reporter activity |
|
no |
|
Wnt signaling |
Functional genomic analysis of the Wnt-wingless signaling pathway. |
DasGupta et al. |
2005 |
15817814 |
Cell line |
Clone 8 |
Wnt signaling |
Dual luciferase |
DRSC |
|
dsRNA |
Z-score |
> |
|
|
32850 |
FBgn0027335 |
l(1)G0003 |
GM01994 |
sp |
none |
|
no |
library: DGC1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
32850 |
FBgn0025623, FBgn0027335 |
CG12467, l(1)G0003 |
np |
sp |
none |
|
no |
library: DGC1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
32850 |
FBgn0025623, FBgn0027335 |
CG12467, l(1)G0003 |
LD11354 |
sp |
none |
|
no |
library: DGC1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
GR00157-A |
32850 |
|
CG6606 |
DRSC33053 |
-0.24 |
Downregulation of Wg pathway |
|
no |
|
Wg pathway regulation |
A case study of the reproducibility of transcriptional reporter cell-based RNAi screens in Drosophila. |
DasGupta et al. |
2007 |
17903264 |
Cell line |
rp |
rp |
Luminescence |
DRSC-v |
Selected genes |
dsRNA |
log ratio |
> 30 % difference from control |
|
GR00157-A |
32850 |
|
l(1)G0003/CG6606 |
DRSC33054 |
0.15 |
Upregulation of Wg pathway |
|
no |
|
Wg pathway regulation |
A case study of the reproducibility of transcriptional reporter cell-based RNAi screens in Drosophila. |
DasGupta et al. |
2007 |
17903264 |
Cell line |
rp |
rp |
Luminescence |
DRSC-v |
Selected genes |
dsRNA |
log ratio |
> 30 % difference from control |
|
GR00218-S |
32850 |
CG6606 |
|
AMB18217 |
-0.24 |
none |
|
no |
|
Hippo pathway regulation |
Salt-inducible kinases regulate growth through the Hippo signalling pathway in Drosophila |
Wehr et al. |
2013 |
23263283 |
Cell line |
S2R+ |
Hippo pathway reporter |
Luminescence |
np |
Genome-wide |
dsRNA |
Z-score |
> 3 OR < -3 |
Author-submitted data. Primary screen |
GR00311-A |
32850 |
FBgn0027335 |
Rip11 |
DRSC20000 |
np |
none |
|
|
|
Actin and microtubule morphology |
Comparative RNAi screening identifies a conserved core metazoan actinome by phenotype |
Rohn et al. |
2011 |
21893601 |
Cell line |
S2R+ |
Alpha-tubulin and F-actin protein expression |
Fluorescence |
DRSC |
Genome-wide |
dsRNA |
Visual inspection |
np |
Exact phenotypes are shown in the comment section. Several genes were indicated as hits but no phenotype was provided. The screen data plus images is available at http://jcb-dataviewer.rupress.org/jcb/browse/4609/S2. |
GR00335-A |
32850 |
FBgn0027335 |
Rip11 |
HMS01792 |
np |
none |
|
|
|
Germline stem cell (GSC) regulation |
A Regulatory Network of Drosophila Germline Stem Cell Self-Renewal |
Yan et al. |
2014 |
24576427 |
Tissue |
MTD-GAL4 or UAS-dcr2; nanos-GAL4 |
Spectrin and vasa protein expression |
Fluorescence |
TRiP |
Selected genes |
UAS-IR construct |
Visual inspection |
np |
More detailed phenotypes for some genes are shown in the comment. Various VALIUM vectors were used. |
|
32850 |
FBgn0027335 |
np |
np |
sp |
none |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|