| GR00002-A |
34735 |
FBgn0032499 |
CG6116 |
DRSC02932 |
1.849010509 |
none |
|
no |
|
Lipid storage |
COPI complex is a regulator of lipid homeostasis. |
Beller et al. |
2008 |
19067489 |
Cell line |
Kc167 |
Nuclear to lipid droplet cross-sectional area |
Fluorescence |
np |
Genome-wide |
dsRNA |
B-score |
> 2 OR < -1.7 |
Additional information about a secondary screen with non-overlaping dsRNAs |
GR00002-A |
34735 |
FBgn0032499 |
CG6116 |
DRSC02932 |
-0.019454889 |
none |
|
no |
|
Lipid storage |
COPI complex is a regulator of lipid homeostasis. |
Beller et al. |
2008 |
19067489 |
Cell line |
Kc167 |
Nuclear to lipid droplet cross-sectional area |
Fluorescence |
np |
Genome-wide |
dsRNA |
B-score |
> 2 OR < -1.7 |
Additional information about a secondary screen with non-overlaping dsRNAs |
GR00014-A |
34735 |
|
CG6116 |
DRSC02932 |
strong |
Decreased Flag-Mad nuclear accumulation |
|
no |
|
Dpp pathway regulation |
Msk is required for nuclear import of TGF-{beta}/BMP-activated Smads. |
Xu et al. |
2007 |
17785517 |
Cell line |
S2R+ |
Flag-Mad protein expression and subcellular location |
Fluorescence |
rp |
Genome-wide |
dsRNA |
Visual inspection |
np |
|
GR00031-A-1 |
34735 |
|
|
HFA02932 |
-0.5 |
none |
|
yes |
|
Cell growth and viability (1) |
Genome-wide RNAi analysis of growth and viability in Drosophila cells. |
Boutros et al. |
2004 |
14764878 |
Cell line |
Kc167 |
Cell number and viability |
Luminescence |
Custom-made (HFA) |
Genome-wide |
dsRNA |
Z-score |
> |
|
GR00031-A-2 |
34735 |
|
|
HFA02932 |
-0.2 |
none |
|
no |
|
Cell growth and viability (2) |
Genome-wide RNAi analysis of growth and viability in Drosophila cells. |
Boutros et al. |
2004 |
14764878 |
Cell line |
S2R+ |
Cell number and viability |
Luminescence |
Custom-made (HFA) |
Genome-wide |
dsRNA |
Z-score |
> |
|
|
34735 |
FBgn0032499 |
CG6116 |
LD05963 |
sp |
none |
|
no |
library: DGC1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
GR00189-A-1 |
34735 |
FBgn0032499 |
CG6116 |
BKN20047 |
np |
Upregulation of Notch pathway |
|
no |
|
Notch pathway regulation (1) |
A combined ex vivo and in vivo RNAi screen for notch regulators in Drosophila reveals an extensive notch interaction network. |
Saj et al. |
2010 |
20493818 |
Cell line |
S2 |
Notch pathway reporter |
Luminescence |
BKN |
Genome-wide |
dsRNA |
Complex, sp |
Complex criteria |
|
GR00218-S |
34735 |
CG6116 |
|
AMB22330 |
-1.84 |
none |
|
no |
|
Hippo pathway regulation |
Salt-inducible kinases regulate growth through the Hippo signalling pathway in Drosophila |
Wehr et al. |
2013 |
23263283 |
Cell line |
S2R+ |
Hippo pathway reporter |
Luminescence |
np |
Genome-wide |
dsRNA |
Z-score |
> 3 OR < -3 |
Author-submitted data. Primary screen |
GR00239-A-1 |
34735 |
CG6116 |
|
6116R |
sp |
none |
|
no |
|
Glycosylation regulation (1) |
Identification of genes required for neural-specific glycosylation using functional genomics. |
Yamamoto-Hino et al. |
2010 |
21203496 |
Tissue |
GMR-GAL4 |
Chaoptin (Chp) protein expression, alpha1,3-fucose, alpha1,6-fucose, (GlcNAc)n, GlcNAcb1-4GlcNAc and mannose Chp glycosylation and viability |
Luminescence |
np |
Selected genes |
UAS-IR construct |
Z-score |
> 3 |
|
GR00311-A |
34735 |
FBgn0032499 |
CG6116 |
DRSC02932 |
np |
none |
|
|
|
Actin and microtubule morphology |
Comparative RNAi screening identifies a conserved core metazoan actinome by phenotype |
Rohn et al. |
2011 |
21893601 |
Cell line |
S2R+ |
Alpha-tubulin and F-actin protein expression |
Fluorescence |
DRSC |
Genome-wide |
dsRNA |
Visual inspection |
np |
Exact phenotypes are shown in the comment section. Several genes were indicated as hits but no phenotype was provided. The screen data plus images is available at http://jcb-dataviewer.rupress.org/jcb/browse/4609/S2. |
GR00335-A |
34735 |
FBgn0032499 |
Uvrag |
HMS01357 |
np |
Embryonic lethal |
|
|
embryonic lethal, most white |
Germline stem cell (GSC) regulation |
A Regulatory Network of Drosophila Germline Stem Cell Self-Renewal |
Yan et al. |
2014 |
24576427 |
Tissue |
MTD-GAL4 or UAS-dcr2; nanos-GAL4 |
Spectrin and vasa protein expression |
Fluorescence |
TRiP |
Selected genes |
UAS-IR construct |
Visual inspection |
np |
More detailed phenotypes for some genes are shown in the comment. Various VALIUM vectors were used. |
|
34735 |
np |
np |
HFA02932 |
-0.11 |
none |
|
|
fold change: 1.09 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
34735 |
FBgn0032499 |
np |
np |
sp |
none |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|