Gene2Function

RNAi

Gene Info

Species: Human (Homo sapiens)
GeneID: 8473
Symbol: OGT
Description: O-linked N-acetylglucosamine (GlcNAc) transferase

DataSource: http://genomernai.dkfz.de/v16/genedetails/8473

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Stable_ID	Entrez_ID	Gene_ID	Gene_Symbol	Reagent_ID	Score	Phenotype	Follow_Up	Comment	Screen_Title	Publication_Title	Authors	Publication_Year	Pubmed_ID	Biosource	Biomodel	Assay	Method	Library	Scope	Reagent_Type	Score_Type	Cutoff	Notes
GR00053-A	8473	NM_181672	OGT	np	sp	none	no		Genome stability	A genome-wide siRNA screen reveals diverse cellular processes and pathways that mediate genome stability.	Paulsen et al.	2009	19647519	Cell line	HeLa	gamma-H2AX phosphorylation and DNA content	Fluorescence	siARRAY human genome siRNA library	Genome-wide	siRNA	p-value	Complex criteria	Confidence groupings from 4 to 1 (highest level of confidence in group 4)
GR00054-A	8473	NM_181672	OGT	np	0.942	none	no		Combinatorial effect with paclitaxel	Synthetic lethal screen identification of chemosensitizer loci in cancer cells.	Whitehurst et al.	2007	17429401	Cell line	NCI-H1155	Viability (synthetic lethal)	ATP level	# G-005000-01	Genome-wide	siRNA	Paclitaxel/control ratio	Complex criteria	Additional information about 87 high-confidence hits
GR00056-A	8473	NM_181672	OGT	np	0.912	none	no		Melanogenesis	Genome-wide siRNA-based functional genomics of pigmentation identifies novel genes and pathways that impact melanogenesis in human cells.	Ganesan et al.	2008	19057677	Cell line	MNT-1	Melanin protein expression and viability	Absorbance and luminescence	rp	Genome-wide	siRNA	Normalized absorbance ratio	> 2 standard deviations below mean	Additional information about a secondary screen (retest to determine false-positive rate)
GR00057-A-1	8473	NM_181672	OGT	M-019111-00	0.8	none	no		Wnt/beta-catenin pathway regulation (1)	A genome-wide RNAi screen for Wnt/beta-catenin pathway components identifies unexpected roles for TCF transcription factors in cancer.	Tang et al.	2008	18621708	Cell line	HeLa	Wnt pathway reporter	Luminescence	Human siArray siRNA library	Genome-wide	siRNA	Z-score	> 4	Screen without Wnt3A stimulation. Additional information about secondary screens (Dharmacon and Qiagen libraries).
GR00057-A-2	8473	NM_181672	OGT	M-019111-00	sp	none	no		Wnt/beta-catenin pathway regulation (2)	A genome-wide RNAi screen for Wnt/beta-catenin pathway components identifies unexpected roles for TCF transcription factors in cancer.	Tang et al.	2008	18621708	Cell line	HeLa	Wnt pathway reporter	Luminescence	Human siArray siRNA library	Genome-wide	siRNA	Complex, SP	Complex criteria	Screen with Wnt3A stimulation. Additional information about secondary screens (Dharmacon and Qiagen libraries).
GR00095-A	8473	NM_003605	OGT	np	np	none			p53 pathway components	A large-scale RNAi screen in human cells identifies new components of the p53 pathway	Berns et al.	2004	15042092	Cell line	BJ-TERT-tsLT fibroblasts	Proliferation	Colony-forming cell assay	Nki library	Genome-wide	shRNA	np	np
GR00098-A-1	8473	ENSG00000147162	OGT	ENSG00000147162	sp	none	no		Cell division (1)	Genome-scale RNAi profiling of cell division in human tissue culture cells.	Kittler et al.	2007	17994010	Cell line	HeLa	Cell number and DNA content	Laser scanning cytometry	rp	Genome-wide	esiRNA	Complex, sp	Complex criteria
GR00123-A	8473	NM_003605	OGT	150303, 150301, 150302	np	none			Combinatorial effect with nutlin-3	An shRNA barcode screen provides insight into cancer cell vulnerability to MDM2 inhibitors	Brummelkamp et al.	2006	16474381	Cell line	MCF-7	Viability	Fluoresence	Nki library	Genome-wide	shRNA	log2 ratio	np
GR00133-A-1	8473	8473	OGT	np	0.262545	none	no		Salmonella enterica subspecies 1 serovar Typhimurium invasion (1)	RNAi screen of Salmonella invasion shows role of COPI in membrane targeting of cholesterol and Cdc42.	Misselwitz et al.	2011	21407211	Cell line	HeLa	Gentamycin protection invasion assay	Fluorescence	Druggable genome library V2.0	Druggable genes	siRNA	log2 median	Complex criteria
GR00149-A-1	8473	8473	OGT	13301	24.35	none	no		Ciliogenesis and cilium length (1)	Functional genomic screen for modulators of ciliogenesis and cilium length.	Kim et al.	2010	20393563	Cell line	htRPE	Smoothed protein expression	Fluorescence	Human druggable genome siRNA library V3.1	Druggable genes	siRNA	Normalized percent inhibition	> 1.5 OR < -1.5 standard deviations from mean
GR00149-A-1	8473	8473	OGT	13301	22.44	none	no		Ciliogenesis and cilium length (1)	Functional genomic screen for modulators of ciliogenesis and cilium length.	Kim et al.	2010	20393563	Cell line	htRPE	Smoothed protein expression	Fluorescence	Human druggable genome siRNA library V3.1	Druggable genes	siRNA	Normalized percent inhibition	> 1.5 OR < -1.5 standard deviations from mean
GR00149-A-1	8473	8473	OGT	112452	-4.14	none	no		Ciliogenesis and cilium length (1)	Functional genomic screen for modulators of ciliogenesis and cilium length.	Kim et al.	2010	20393563	Cell line	htRPE	Smoothed protein expression	Fluorescence	Human druggable genome siRNA library V3.1	Druggable genes	siRNA	Normalized percent inhibition	> 1.5 OR < -1.5 standard deviations from mean
GR00149-A-1	8473	8473	OGT	112452	-10.61	none	no		Ciliogenesis and cilium length (1)	Functional genomic screen for modulators of ciliogenesis and cilium length.	Kim et al.	2010	20393563	Cell line	htRPE	Smoothed protein expression	Fluorescence	Human druggable genome siRNA library V3.1	Druggable genes	siRNA	Normalized percent inhibition	> 1.5 OR < -1.5 standard deviations from mean
GR00149-A-1	8473	8473	OGT	112453	362.61	none	no		Ciliogenesis and cilium length (1)	Functional genomic screen for modulators of ciliogenesis and cilium length.	Kim et al.	2010	20393563	Cell line	htRPE	Smoothed protein expression	Fluorescence	Human druggable genome siRNA library V3.1	Druggable genes	siRNA	Normalized percent inhibition	> 1.5 OR < -1.5 standard deviations from mean
GR00149-A-1	8473	8473	OGT	112453	303.73	none	no		Ciliogenesis and cilium length (1)	Functional genomic screen for modulators of ciliogenesis and cilium length.	Kim et al.	2010	20393563	Cell line	htRPE	Smoothed protein expression	Fluorescence	Human druggable genome siRNA library V3.1	Druggable genes	siRNA	Normalized percent inhibition	> 1.5 OR < -1.5 standard deviations from mean
GR00149-A-1	8473	8473	OGT	112454	48.55	none	no		Ciliogenesis and cilium length (1)	Functional genomic screen for modulators of ciliogenesis and cilium length.	Kim et al.	2010	20393563	Cell line	htRPE	Smoothed protein expression	Fluorescence	Human druggable genome siRNA library V3.1	Druggable genes	siRNA	Normalized percent inhibition	> 1.5 OR < -1.5 standard deviations from mean
GR00149-A-1	8473	8473	OGT	112454	42.27	none	no		Ciliogenesis and cilium length (1)	Functional genomic screen for modulators of ciliogenesis and cilium length.	Kim et al.	2010	20393563	Cell line	htRPE	Smoothed protein expression	Fluorescence	Human druggable genome siRNA library V3.1	Druggable genes	siRNA	Normalized percent inhibition	> 1.5 OR < -1.5 standard deviations from mean
GR00151-A-1	8473	ENSG00000147162	OGT	np	0.843	none	no		Homologous recombination DNA double-strand break repair (HR-DSBR) (1)	A genome-scale DNA repair RNAi screen identifies SPG48 as a novel gene associated with hereditary spastic paraplegia.	SÅ‚abicki et al.	2010	20613862	Cell line	HeLa	(HR-DSBR) DR-GFP reporter	Flow cytometry	Custom-made	Genome-wide	esiRNA	Z-score	< -2 OR > 2
GR00180-A-1	8473	8473	OGT	PL-50013	0.837	none	no		Hepatitis C virus replication (1)	A functional genomic screen identifies cellular cofactors of hepatitis C virus replication.	Tai et al.	2009	19286138	Cell line	Huh7/Rep-Feo	HCV replicon RNA copy number	Luminescence	siARRAY Human Genome siRNA Library	Genome-wide	siRNA	q-value	Complex criteria
GR00184-A-1	8473	NM_181672	OGT	M-019111-00	-1.02203607978168	none	no		Self-renewal and pluripotency in human embryonic stem cells (1)	A genome-wide RNAi screen reveals determinants of human embryonic stem cell identity.	Chia et al.	2010	20953172	Cell line	hESC H1	POU5F1 protein expression	Fluorescence	SMARTpool siRNA library	Genome-wide	siRNA	Z-score	< -2
GR00196-A-1	8473	ENSG00000147162		np	sp	none	no		TP53 interactions (1)	A systematic RNAi synthetic interaction screen reveals a link between p53 and snoRNP assembly.	Krastev et al.	2011	21642980	Cell line	HCT116 ( wildtype and TP53 knockout)	TP53 protein expression and viability	Fluorescence	rp	Genome-wide	esiRNA	Complex, sp	Complex criteria
GR00197-A-1	8473	8473	OGT	M-019111-00	-0.00517822	none	no		Human papillomavirus oncogene expression regulation (1)	Genome-wide siRNA screen identifies SMCX, EP400, and Brd4 as E2-dependent regulators of human papillomavirus oncogene expression.	Smith et al.	2010	20133580	Cell line	C33A/BE2/18LCR c4	HPV18 LCR reporter activity	Luminescence	Human siGENOME SMARTpool library	Genome-wide	siRNA	Z-score	>	Author-submitted data. Phenotype strength according to Z-scores: weak: 2 - 3; moderate: 3 - 5; strong: > 5
	8473		OGT	np	np	Decreased viability in pancreas lineage	no	pancreas: no filter, KS
GR00236-A-1	8473	8473	OGT	M-019111-00	0.705027955569892	none	no		Homologous recombination DNA double-strand break repair (HR-DSBR) (1)	A genome-wide homologous recombination screen identifies the RNA-binding protein RBMX as a component of the DNA-damage response.	Adamson et al.	2012	22344029	Cell line	DR-U2OS	(HR-DSBR) DR-GFP reporter and DNA content	Fluorescence	Human siGENOME siRNA (G-005000-05)	Genome-wide	siRNA	Relative HR ratio	< ~0.4 OR > 1.88	Cutoff values correspond 2 standard deviations from the screen-wide mean
GR00240-S-1	8473	NM_181672	OGT	M-019111-00	1.09	none	yes		TRAIL-induced apoptosis (1)	A synthetic lethal screen identifies FAT1 as an antagonist of caspase-8 in extrinsic apoptosis.	Kranz and Boutros	2014	24442637	Cell line	U251MG	Viability	Luminescence	SMART-pool siRNA	Genome-wide	siRNA	Z-score	> 4	Author-submitted data
GR00240-S-2	8473	NM_181672	OGT	M-019111-00	-0.07	none	no	Z-score 1.243	TRAIL-induced apoptosis (2)	A synthetic lethal screen identifies FAT1 as an antagonist of caspase-8 in extrinsic apoptosis.	Kranz and Boutros	2014	24442637	Cell line	U251MG	Viability (synthetic lethal)	Luminescence	SMART-pool siRNA	Genome-wide	siRNA	Differential score	> 3.6 AND viability Z-score < 4	Author-submitted data. Z-scores from viability screen (1) are considered in score interpretation for this screen.
GR00242-A-1	8473	NM_181672	OGT	np	sp	none	no		Selective autophagy regulation (1)	Image-based genome-wide siRNA screen identifies selective autophagy factors.	Orvedahl et al.	2011	22020285	Cell line	HeLa/GFP-LC3	Sindbis virus (SIN) capsid SIN-mCherry.capsid and autophagosome GFPâ€“LC3 protein expression	Fluorescence	siGenome	Genome-wide	siRNA	Z-score	Complex criteria
GR00247-A-1	8473		OGT	np	sp	none		rank: 15356	Regulation of FOXO1 nuclear localization (1)	Whole genome siRNA cell-based screen links mitochondria to Akt signaling network through uncoupling of electron transport chain.	Senapedis et al.	2011	21460183	Cell line	U2OS	EGFP-FOXO1a protein expression and DNA content	Fluorescence	Human Genome library	Genome-wide	siRNA	Complex, sp	Complex criteria
GR00249-S	8473	8473	OGT	J-019111-05	2.65855	Increased vaccinia virus (VACV) infection	no	number of cells compared to control (%): 77.41	Vaccinia virus (VACV) infection	Human genome-wide RNAi screen reveals a role for nuclear pore proteins in poxvirus morphogenesis.	Sivan et al.	2013	23401514	Cell line	HeLa	Vaccinia virus VACV IHD-J/GFP protein expression and DNA content	Fluorescence	Silencer Select Version 4, siGENOME SMARTpool and OnTargetPlus	Genome-wide	siRNA	Z-score	>	Author-submitted data. Primary screen. Decreased viability phenotype if number of cells compared to control < 50 %.
GR00249-S	8473	8473	OGT	M-019111-00	0.14873	Decreased viability	no	number of cells compared to control (%): 29.10	Vaccinia virus (VACV) infection	Human genome-wide RNAi screen reveals a role for nuclear pore proteins in poxvirus morphogenesis.	Sivan et al.	2013	23401514	Cell line	HeLa	Vaccinia virus VACV IHD-J/GFP protein expression and DNA content	Fluorescence	Silencer Select Version 4, siGENOME SMARTpool and OnTargetPlus	Genome-wide	siRNA	Z-score	>	Author-submitted data. Primary screen. Decreased viability phenotype if number of cells compared to control < 50 %.
GR00249-S	8473	8473	OGT	s16093	-0.32631	none	no	number of cells compared to control (%): 92.29	Vaccinia virus (VACV) infection	Human genome-wide RNAi screen reveals a role for nuclear pore proteins in poxvirus morphogenesis.	Sivan et al.	2013	23401514	Cell line	HeLa	Vaccinia virus VACV IHD-J/GFP protein expression and DNA content	Fluorescence	Silencer Select Version 4, siGENOME SMARTpool and OnTargetPlus	Genome-wide	siRNA	Z-score	>	Author-submitted data. Primary screen. Decreased viability phenotype if number of cells compared to control < 50 %.
GR00249-S	8473	8473	OGT	s16094	-0.20217	none	no	number of cells compared to control (%): 87.19	Vaccinia virus (VACV) infection	Human genome-wide RNAi screen reveals a role for nuclear pore proteins in poxvirus morphogenesis.	Sivan et al.	2013	23401514	Cell line	HeLa	Vaccinia virus VACV IHD-J/GFP protein expression and DNA content	Fluorescence	Silencer Select Version 4, siGENOME SMARTpool and OnTargetPlus	Genome-wide	siRNA	Z-score	>	Author-submitted data. Primary screen. Decreased viability phenotype if number of cells compared to control < 50 %.
GR00249-S	8473	8473	OGT	s16095	-0.08633	none	no	number of cells compared to control (%): 86.63	Vaccinia virus (VACV) infection	Human genome-wide RNAi screen reveals a role for nuclear pore proteins in poxvirus morphogenesis.	Sivan et al.	2013	23401514	Cell line	HeLa	Vaccinia virus VACV IHD-J/GFP protein expression and DNA content	Fluorescence	Silencer Select Version 4, siGENOME SMARTpool and OnTargetPlus	Genome-wide	siRNA	Z-score	>	Author-submitted data. Primary screen. Decreased viability phenotype if number of cells compared to control < 50 %.
GR00253-A	8473	NM_181672	OGT	np	-2.639	Decreased hepcidin::fluc mRNA expression			hepcidin regulation	Unbiased RNAi screen for hepcidin regulators links hepcidin suppression to proliferative Ras/RAF and nutrient-dependent mTOR signaling.	Mleczko-Sanecka et al.	2014	24385536	Cell line	Huh7	hepcidin::fluc mRNA expression	Luminescence	siGenome siARRAY SMARTpool	Genome-wide	siRNA	Z-score	>	Cutoff <
GR00255-A-1	8473	8473	OGT	TRCN0000035064, TRCN0000035065, TRCN0000035066, TRCN0000035067, TRCN0000035068	-0.214438335	none			Negative genetic interactions (1)	A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities.	Vizeacoumar et al.	2013	24104479	Cell line	HCT116	shRNA abundance	Microarray	np	Genome-wide	shRNA	differential Gene Activity Ranking Profile (dGARP)	< -1.0	HCT116 BLM-/- and HCT116 BLM+/+ cells used. Cutoff corresponds to p-value < 0.05. Additional information about a secondary screen (genetic interactions with Cetuximab/Erbitux in LIM1215 cells)
GR00255-A-2	8473	8473	OGT	TRCN0000035064, TRCN0000035065, TRCN0000035066, TRCN0000035067, TRCN0000035068	-0.257251784	none			Negative genetic interactions (2)	A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities.	Vizeacoumar et al.	2013	24104479	Cell line	HCT116	shRNA abundance	Microarray	np	Genome-wide	shRNA	differential Gene Activity Ranking Profile (dGARP)	< -1.0	HCT116 MUS81-/- and HCT116 MUS81+/+ cells used. Cutoff corresponds to p-value < 0.05. Additional information about a secondary screen (genetic interactions with Cetuximab/Erbitux in LIM1215 cells)
GR00255-A-3	8473	8473	OGT	TRCN0000035064, TRCN0000035065, TRCN0000035066, TRCN0000035067, TRCN0000035068	-0.356346068	none			Negative genetic interactions (3)	A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities.	Vizeacoumar et al.	2013	24104479	Cell line	HCT116	shRNA abundance	Microarray	np	Genome-wide	shRNA	differential Gene Activity Ranking Profile (dGARP)	< -1.2	HCT116 PTEN-/- and HCT116 PTEN+/+ cells used. Cutoff corresponds to p-value < 0.05. Additional information about a secondary screen (genetic interactions with Cetuximab/Erbitux in LIM1215 cells)
GR00255-A-4	8473	8473	OGT	TRCN0000035064, TRCN0000035065, TRCN0000035066, TRCN0000035067, TRCN0000035068	0.257388875	none			Negative genetic interactions (4)	A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities.	Vizeacoumar et al.	2013	24104479	Cell line	HCT116	shRNA abundance	Microarray	np	Genome-wide	shRNA	differential Gene Activity Ranking Profile (dGARP)	< -1.2	HCT116 PTTG1-/- and HCT116 PTTG1+/+ cells used. Cutoff corresponds to p-value < 0.05. Additional information about a secondary screen (genetic interactions with Cetuximab/Erbitux in LIM1215 cells)
GR00255-A-5	8473	8473	OGT	TRCN0000035064, TRCN0000035065, TRCN0000035066, TRCN0000035067, TRCN0000035068	0.423716279	none			Negative genetic interactions (5)	A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities.	Vizeacoumar et al.	2013	24104479	Cell line	HCT116	shRNA abundance	Microarray	np	Genome-wide	shRNA	differential Gene Activity Ranking Profile (dGARP)	< -0.8	HCT116 KRASG13D/- and HCT116 KRAS+/- cells used. Cutoff corresponds to p-value < 0.05. Additional information about a secondary screen (genetic interactions with Cetuximab/Erbitux in LIM1215 cells)
GR00293-A	8473		OGT	np	1.2	none			Combinatorial effect with paclitaxel	Mechanisms Promoting Escape from Mitotic Stressâˆ’Induced Tumor Cell Death	Sinnott et al.	2014	24860162	Cell line	HCC366	Viability	Luminescence	Thermo-Fisher	Genome-wide	siRNA	Z-score	< -2.5	Final hits according to the author are indicated in the comment.
GR00300-A	8473		OGT	TRCN0000035068, TRCN0000035067, TRCN0000035066, TRCN0000035065, TRCN0000035064	0	none			Combinatorial effect with RAF inhibitor PLX4720	A genome-scale RNA interference screen implicates NF1 loss in resistance to RAF inhibition.	Whittaker et al.	2013	23288408	Cell line	A375	shRNA abundance	Sequencing	TRC	Genome-wide	shRNA	Number of shRNAs ranked Top1000	> 2	The A375 cell line used here harbours the BRAF V600E mutation and is therefore sensitive to RAF inhibitors.
GR00303-A	8473	NM_181672	OGT	np	0.34	none			Clear cell renal cell carcinoma (ccRCC) survival regulation	Genome-wide RNA interference analysis of renal carcinoma survival regulators identifies MCT4 as a Warburg effect metabolic target	Gerlinger et al.	2012	22362593	Cell line	VHL-deficient RCC4	Proliferation and Viability	Fluorescence	np	Genome-wide	siRNA	Z-score	<	In the phenotype data duplicates were in the original document, which have been removed.
GR00310-A-1	8473	8473	OGT	np	0.55	none			Sindbis virus (SINV) infection (1)	Genome-Wide RNAi Screen Identifies Novel Host Proteins Required for Alphavirus Entry	Ooi et al.	2013	24367265	Cell line	U2OS	Sindbis virus (SINV) reporter	Luminescence	Ambion Silencer V3	Genome-wide	siRNA	Z-score	< -3 OR > 2
	8473	8473	OGT	np	22	none		73,6% viability
GR00313-A	8473	NM_003605, NM_181672, NM_181673	OGT	np	3.36	none			TNF-alpha pathway regulation	A Genome-Wide RNA Interference Screen Identifies Caspase 4 as a Factor Required for Tumor Necrosis Factor Alpha Signaling.	Nickles et al.	2012	22733992	Cell line	HEK293T	NFkappaB pathway reporter	Luminescence	Qiagen	Genome-wide	siRNA	Z-score	<	Additional filters were a reduction in firefly luciferase levels by at least 50% compared to the mean of the experiment and a concomitant reduction of renilla luciferase expression of not more than 30%.
GR00318-A	8473	8473	OGT	np	0.702	none		siRNA set: druggable genome	Huntingtin toxicity	A Genome-Scale RNAâ€“Interference Screen Identifies RRAS Signaling as a Pathologic Feature of Huntingtonâ€™s Disease	Miller et al.	2012	23209424	Cell line	HEK293T	Caspase 3/7 activity	Fluorescence	Dharmacon	Selected genes	siRNA	Sum of normalized caspase 3/7 activity mean and standard error	< 0.683	HEK293T cells were cotransfected with mutant Huntingtin fused to GFP (Htt1-558141Q-GFP).
GR00343-S	8473	8473	OGT	TRCN0000035066	0.7299999999999986	none			Lentiviral shRNA "Achilles Heel" screen	Inhibition of the mitochondrial protease, ClpP, as a therapeutic strategy for human acute myeloid leukemia	Cole et al.	2015	26058080	Cell line	K562	shRNA abundance	Fluorescence	Lentiviral shRNA library	Genome-wide	shRNA	Log2 ratio	<	Comparison of day 21 vs. day 0 abundance data
GR00343-S	8473	8473	OGT	TRCN0000035068	1.1425	none			Lentiviral shRNA "Achilles Heel" screen	Inhibition of the mitochondrial protease, ClpP, as a therapeutic strategy for human acute myeloid leukemia	Cole et al.	2015	26058080	Cell line	K562	shRNA abundance	Fluorescence	Lentiviral shRNA library	Genome-wide	shRNA	Log2 ratio	<	Comparison of day 21 vs. day 0 abundance data
GR00343-S	8473	8473	OGT	TRCN0000035065	0.9000000000000004	none			Lentiviral shRNA "Achilles Heel" screen	Inhibition of the mitochondrial protease, ClpP, as a therapeutic strategy for human acute myeloid leukemia	Cole et al.	2015	26058080	Cell line	K562	shRNA abundance	Fluorescence	Lentiviral shRNA library	Genome-wide	shRNA	Log2 ratio	<	Comparison of day 21 vs. day 0 abundance data
GR00343-S	8473	8473	OGT	TRCN0000035067	0.6750000000000025	none			Lentiviral shRNA "Achilles Heel" screen	Inhibition of the mitochondrial protease, ClpP, as a therapeutic strategy for human acute myeloid leukemia	Cole et al.	2015	26058080	Cell line	K562	shRNA abundance	Fluorescence	Lentiviral shRNA library	Genome-wide	shRNA	Log2 ratio	<	Comparison of day 21 vs. day 0 abundance data
GR00343-S	8473	8473	OGT	TRCN0000035064	0.692499999999999	none			Lentiviral shRNA "Achilles Heel" screen	Inhibition of the mitochondrial protease, ClpP, as a therapeutic strategy for human acute myeloid leukemia	Cole et al.	2015	26058080	Cell line	K562	shRNA abundance	Fluorescence	Lentiviral shRNA library	Genome-wide	shRNA	Log2 ratio	<	Comparison of day 21 vs. day 0 abundance data
	8473		OGT	np	2	Resistant to vaccinia virus (VACV-A4L) infection
GR00351-A-2	8473	8473	OGT	TRCN0000293652, TRCN0000286201, TRCN0000286199, TRCN0000035067, TRCN0000298541	sp	Decreased vaccinia virus (VACV-LREV ) gene expression			Orthopoxvirus infection (2)	The Master Regulator of the Cellular Stress Response (HSF1) Is Critical for Orthopoxvirus Infection	Filone et al.	2014	24516381	Cell line	A549	Vaccinia virus (VACV-LREV) gene expression	Fluorescence	TRC	Selected genes	shRNA	Normalized RFU	Complex criteria	The vaccinia virus VACV-LREV expressed soluble Venus under an early promoter and soluble mCherry under a late promoter.
GR00363-A	8473	8473	OGT	SI00053508, SI02665131, SI02631412, 112454, 112452, esi8688, SI00053522, 112453	sp	Increased epidermal growth factor (EGF) endocytosis, decreased transferrin (TF) endocytosis		weak but specific	Endocytosis regulation	Systems survey of endocytosis by multiparametric image analysis.	Collinet et al.	2010	20190736	Cell line	HeLa	Transferrin (TF) and epidermal growth factor (EGF) subcellular localisation, DNA content	Fluorescence	Ambion, Qiagen and esiRNA library (Kittler et al.)	Genome-wide	siRNA	Complex, sp	Complex criteria	Two hit categories: "strong" (maximum of Prob Chi2, Prob Chi2 EGF, Prob Chi2 Tfn > 0.95) and "weak but specific" (maximum of Prob Chi2, Prob Chi2 EGF, Prob Chi2 Tfn < 0.95 but Phenoscore > 0.95). Additional information about secondary screens with kinase and phospatase libraries.
GR00366-A-1	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.941735392764138	none		OGT_1_10111	Context-specific genetic dependencies (1)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	22RV1_PROSTATE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-10	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	1.16661114879065	none		OGT_1_10111	Context-specific genetic dependencies (10)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	ACHN_KIDNEY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-100	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-2.75954125854443	Decreased shRNA abundance (Z-score < -2)		OGT_1_10111	Context-specific genetic dependencies (100)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	LAMA84_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-101	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-1.28902854617382	none		OGT_1_10111	Context-specific genetic dependencies (101)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	LK2_LUNG	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-102	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.295411230318103	none		OGT_1_10111	Context-specific genetic dependencies (102)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	LN215_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-103	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.350169271537478	none		OGT_1_10111	Context-specific genetic dependencies (103)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	LN229_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-104	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.215790532487765	none		OGT_1_10111	Context-specific genetic dependencies (104)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	LN235_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-105	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.822878953540013	none		OGT_1_10111	Context-specific genetic dependencies (105)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	LN319_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-106	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.659219504167426	none		OGT_1_10111	Context-specific genetic dependencies (106)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	LN340_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-107	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.391990430759421	none		OGT_1_10111	Context-specific genetic dependencies (107)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	LN382_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-108	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.326851106491253	none		OGT_1_10111	Context-specific genetic dependencies (108)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	LN428_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-109	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.351300740887893	none		OGT_1_10111	Context-specific genetic dependencies (109)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	LN443_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-11	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-1.81238342635325	Decreased shRNA abundance (Z-score < -2)		OGT_1_10111	Context-specific genetic dependencies (11)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	AGS_STOMACH	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-110	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.0576607352436596	none		OGT_1_10111	Context-specific genetic dependencies (110)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	LN464_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-111	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.823703555780953	none		OGT_1_10111	Context-specific genetic dependencies (111)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	LNZ308_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-112	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.639608748581547	none		OGT_1_10111	Context-specific genetic dependencies (112)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	LOVO_LARGE_INTESTINE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-113	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.00926772835068088	none		OGT_1_10111	Context-specific genetic dependencies (113)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	LS411N_LARGE_INTESTINE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-114	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.437641903503091	none		OGT_1_10111	Context-specific genetic dependencies (114)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	LS513_LARGE_INTESTINE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-115	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.717184344958014	none		OGT_1_10111	Context-specific genetic dependencies (115)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	MCF7_BREAST	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-116	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.650961080361899	none		OGT_1_10111	Context-specific genetic dependencies (116)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	MDAMB453_BREAST	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-117	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.182092730971847	none		OGT_1_10111	Context-specific genetic dependencies (117)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	MIAPACA2_PANCREAS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-118	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	1.69522185358989	Increased shRNA abundance (Z-score > 2)		OGT_1_10111	Context-specific genetic dependencies (118)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	MKN7_STOMACH	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-119	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.158395694267878	none		OGT_1_10111	Context-specific genetic dependencies (119)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	MM1S_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-12	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	1.36806147267129	none		OGT_1_10111	Context-specific genetic dependencies (12)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	AM38_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-120	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	1.85813312988587	Increased shRNA abundance (Z-score > 2)		OGT_1_10111	Context-specific genetic dependencies (120)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	MOLM13_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-121	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.844027697036617	none		OGT_1_10111	Context-specific genetic dependencies (121)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	MONOMAC1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-122	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.262769533165109	none		OGT_1_10111	Context-specific genetic dependencies (122)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	MONOMAC6_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-123	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	1.8772104710402	Increased shRNA abundance (Z-score > 2)		OGT_1_10111	Context-specific genetic dependencies (123)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	MV411_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-124	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.860262183311372	none		OGT_1_10111	Context-specific genetic dependencies (124)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	NALM6_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-125	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.0597584231200462	none		OGT_1_10111	Context-specific genetic dependencies (125)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	NB4_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-126	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.157695330818126	none		OGT_1_10111	Context-specific genetic dependencies (126)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	NCIH1299_LUNG	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-127	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.920801308236244	none		OGT_1_10111	Context-specific genetic dependencies (127)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	NCIH1437_LUNG	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-128	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.74797019045477	none		OGT_1_10111	Context-specific genetic dependencies (128)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	NCIH1650_LUNG	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-129	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.789470440067641	none		OGT_1_10111	Context-specific genetic dependencies (129)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	NCIH1792_LUNG	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-13	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.0172599597612548	none		OGT_1_10111	Context-specific genetic dependencies (13)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	AML193_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-130	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.0814455935398008	none		OGT_1_10111	Context-specific genetic dependencies (130)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	NCIH196_LUNG	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-131	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	1.14967469971662	none		OGT_1_10111	Context-specific genetic dependencies (131)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	NCIH1975_LUNG	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-132	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.69037665419588	none		OGT_1_10111	Context-specific genetic dependencies (132)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	NCIH2052_PLEURA	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-133	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-1.27499924102335	none		OGT_1_10111	Context-specific genetic dependencies (133)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	NCIH2122_LUNG	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-134	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.423106215946548	none		OGT_1_10111	Context-specific genetic dependencies (134)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	NCIH2171_LUNG	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-135	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.405802964487374	none		OGT_1_10111	Context-specific genetic dependencies (135)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	NCIH23_LUNG	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-136	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.400776380161673	none		OGT_1_10111	Context-specific genetic dependencies (136)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	NCIH2452_PLEURA	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-137	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.743953184851649	none		OGT_1_10111	Context-specific genetic dependencies (137)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	NCIH441_LUNG	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-138	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.0646760503368796	none		OGT_1_10111	Context-specific genetic dependencies (138)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	NCIH508_LARGE_INTESTINE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-139	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.101700119245889	none		OGT_1_10111	Context-specific genetic dependencies (139)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	NCIH660_PROSTATE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-14	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-1.19966284775502	none		OGT_1_10111	Context-specific genetic dependencies (14)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	ASPC1_PANCREAS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-140	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.904360054075008	none		OGT_1_10111	Context-specific genetic dependencies (140)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	NCIH661_LUNG	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-141	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.765948496271303	none		OGT_1_10111	Context-specific genetic dependencies (141)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	NCIH716_LARGE_INTESTINE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-142	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.699940830189215	none		OGT_1_10111	Context-specific genetic dependencies (142)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	NCIH838_LUNG	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-143	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.412432736592448	none		OGT_1_10111	Context-specific genetic dependencies (143)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	NCIN87_STOMACH	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-144	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.0168916579157816	none		OGT_1_10111	Context-specific genetic dependencies (144)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	NIHOVCAR3_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-145	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.468191939457599	none		OGT_1_10111	Context-specific genetic dependencies (145)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	NOMO1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-146	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.290906855896165	none		OGT_1_10111	Context-specific genetic dependencies (146)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	OAW42_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-147	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-1.02443424283857	none		OGT_1_10111	Context-specific genetic dependencies (147)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	OCIAML2_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-148	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-1.08971360515737	none		OGT_1_10111	Context-specific genetic dependencies (148)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	OCIAML3_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-149	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.245313564589544	none		OGT_1_10111	Context-specific genetic dependencies (149)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	OCIAML5_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-15	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.313733300434251	none		OGT_1_10111	Context-specific genetic dependencies (15)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	BT20_BREAST	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-150	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.418730808659772	none		OGT_1_10111	Context-specific genetic dependencies (150)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	OE33_OESOPHAGUS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-151	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-1.33831209894134	none		OGT_1_10111	Context-specific genetic dependencies (151)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	OELE_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-152	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.578799152943138	none		OGT_1_10111	Context-specific genetic dependencies (152)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	OPM2_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-153	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.083680603778548	none		OGT_1_10111	Context-specific genetic dependencies (153)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	OV7_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-154	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.113246577419742	none		OGT_1_10111	Context-specific genetic dependencies (154)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	OV90_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-155	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.0433864930021978	none		OGT_1_10111	Context-specific genetic dependencies (155)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	OVCAR4_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-156	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.127815396508253	none		OGT_1_10111	Context-specific genetic dependencies (156)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	OVCAR8_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-157	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.550246469977714	none		OGT_1_10111	Context-specific genetic dependencies (157)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	OVISE_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-158	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-1.47244993137199	none		OGT_1_10111	Context-specific genetic dependencies (158)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	PANC0327_PANCREAS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-159	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-2.80536826995615	Decreased shRNA abundance (Z-score < -2)		OGT_1_10111	Context-specific genetic dependencies (159)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	PANC0813_PANCREAS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-16	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.190444596765131	none		OGT_1_10111	Context-specific genetic dependencies (16)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	BT474_BREAST	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-160	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.420599341533106	none		OGT_1_10111	Context-specific genetic dependencies (160)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	PANC1005_PANCREAS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-161	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.664531967549804	none		OGT_1_10111	Context-specific genetic dependencies (161)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	PLB985_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-162	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.168631978980358	none		OGT_1_10111	Context-specific genetic dependencies (162)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	PSN1_PANCREAS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-163	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.282133741644365	none		OGT_1_10111	Context-specific genetic dependencies (163)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	QGP1_PANCREAS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-164	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	1.72413379671294	Increased shRNA abundance (Z-score > 2)		OGT_1_10111	Context-specific genetic dependencies (164)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	REH_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-165	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.579635954460045	none		OGT_1_10111	Context-specific genetic dependencies (165)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	RKN_SOFT_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-166	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.513877582434257	none		OGT_1_10111	Context-specific genetic dependencies (166)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	RKO_LARGE_INTESTINE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-167	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-1.25979136463932	none		OGT_1_10111	Context-specific genetic dependencies (167)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	RMGI_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-168	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.914369440476753	none		OGT_1_10111	Context-specific genetic dependencies (168)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	RMUGS_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-169	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	1.16641449183312	none		OGT_1_10111	Context-specific genetic dependencies (169)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	RS411_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-17	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.13114766903392	none		OGT_1_10111	Context-specific genetic dependencies (17)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	BXPC3_PANCREAS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-170	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.17083026574841	none		OGT_1_10111	Context-specific genetic dependencies (170)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	RT112_URINARY_TRACT	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-171	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	1.3468772920653	none		OGT_1_10111	Context-specific genetic dependencies (171)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SEM_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-172	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.00199270107988365	none		OGT_1_10111	Context-specific genetic dependencies (172)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SF126_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-173	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-2.22160633180606	Decreased shRNA abundance (Z-score < -2)		OGT_1_10111	Context-specific genetic dependencies (173)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SF172_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-174	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-1.12981890910312	none		OGT_1_10111	Context-specific genetic dependencies (174)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SF295_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-175	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-1.25371523850865	none		OGT_1_10111	Context-specific genetic dependencies (175)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SF767_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-176	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.617528106733876	none		OGT_1_10111	Context-specific genetic dependencies (176)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SJSA1_BONE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-177	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-1.10034146461989	none		OGT_1_10111	Context-specific genetic dependencies (177)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SKCO1_LARGE_INTESTINE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-178	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.385990910832748	none		OGT_1_10111	Context-specific genetic dependencies (178)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SKMEL5_SKIN	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-179	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.718263661140112	none		OGT_1_10111	Context-specific genetic dependencies (179)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SKMM2_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-18	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-1.77826592944654	Decreased shRNA abundance (Z-score < -2)		OGT_1_10111	Context-specific genetic dependencies (18)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	C2BBE1_LARGE_INTESTINE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-180	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.258673204561951	none		OGT_1_10111	Context-specific genetic dependencies (180)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SKNO1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-181	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.343233957550075	none		OGT_1_10111	Context-specific genetic dependencies (181)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SKOV3_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-182	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.715901422029913	none		OGT_1_10111	Context-specific genetic dependencies (182)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SKRC20_KIDNEY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-183	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.45227779645399	none		OGT_1_10111	Context-specific genetic dependencies (183)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SLR20_KIDNEY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-184	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-1.06379592420683	none		OGT_1_10111	Context-specific genetic dependencies (184)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SLR21_KIDNEY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-185	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.11619579248465	none		OGT_1_10111	Context-specific genetic dependencies (185)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SLR23_KIDNEY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-186	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.572298323358828	none		OGT_1_10111	Context-specific genetic dependencies (186)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SLR24_KIDNEY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-187	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-1.61561858291296	none		OGT_1_10111	Context-specific genetic dependencies (187)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SLR25_KIDNEY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-188	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.771256230684098	none		OGT_1_10111	Context-specific genetic dependencies (188)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SLR26_KIDNEY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-189	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	1.10190012980304	none		OGT_1_10111	Context-specific genetic dependencies (189)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SNU1105_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-19	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.583617933979966	none		OGT_1_10111	Context-specific genetic dependencies (19)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	C32_SKIN	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-190	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.470626840236247	none		OGT_1_10111	Context-specific genetic dependencies (190)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SNU840_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-191	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.286199922783026	none		OGT_1_10111	Context-specific genetic dependencies (191)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SNUC1_LARGE_INTESTINE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-192	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.709010177458774	none		OGT_1_10111	Context-specific genetic dependencies (192)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SNUC2A_LARGE_INTESTINE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-193	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-1.90303905785179	Decreased shRNA abundance (Z-score < -2)		OGT_1_10111	Context-specific genetic dependencies (193)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SU8686_PANCREAS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-194	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.689144846090028	none		OGT_1_10111	Context-specific genetic dependencies (194)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SW1417_LARGE_INTESTINE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-195	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.108368771258358	none		OGT_1_10111	Context-specific genetic dependencies (195)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SW1783_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-196	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	1.06445631441862	none		OGT_1_10111	Context-specific genetic dependencies (196)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SW480_LARGE_INTESTINE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-197	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.600810234687565	none		OGT_1_10111	Context-specific genetic dependencies (197)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SW48_LARGE_INTESTINE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-198	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.0931120723442057	none		OGT_1_10111	Context-specific genetic dependencies (198)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	T98G_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-199	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	1.24278343545791	none		OGT_1_10111	Context-specific genetic dependencies (199)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	TC71_BONE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-2	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	1.34048429206415	none		OGT_1_10111	Context-specific genetic dependencies (2)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	697_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-20	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.628176989020302	none		OGT_1_10111	Context-specific genetic dependencies (20)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	CADOES1_BONE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-200	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.258613292984298	none		OGT_1_10111	Context-specific genetic dependencies (200)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	TCCSUP_URINARY_TRACT	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-201	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.343008106210117	none		OGT_1_10111	Context-specific genetic dependencies (201)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	TE10_OESOPHAGUS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-202	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.648638535788179	none		OGT_1_10111	Context-specific genetic dependencies (202)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	TE15_OESOPHAGUS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-203	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.395873744085045	none		OGT_1_10111	Context-specific genetic dependencies (203)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	TE9_OESOPHAGUS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-204	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.944197558028457	none		OGT_1_10111	Context-specific genetic dependencies (204)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	THP1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-205	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.0804216271558611	none		OGT_1_10111	Context-specific genetic dependencies (205)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	TOV112D_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-206	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-1.86589878702186	Decreased shRNA abundance (Z-score < -2)		OGT_1_10111	Context-specific genetic dependencies (206)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	TOV21G_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-207	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.194740106468506	none		OGT_1_10111	Context-specific genetic dependencies (207)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	TT_OESOPHAGUS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-208	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.332413025928992	none		OGT_1_10111	Context-specific genetic dependencies (208)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	TYKNU_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-209	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.945566457358763	none		OGT_1_10111	Context-specific genetic dependencies (209)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	U178_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-21	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.818766834837174	none		OGT_1_10111	Context-specific genetic dependencies (21)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	CAL120_BREAST	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-210	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.424474077676703	none		OGT_1_10111	Context-specific genetic dependencies (210)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	U251MG_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-211	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.224680023005835	none		OGT_1_10111	Context-specific genetic dependencies (211)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	U343_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-212	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.123337333452276	none		OGT_1_10111	Context-specific genetic dependencies (212)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	U87MG_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-213	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.48775143183443	none		OGT_1_10111	Context-specific genetic dependencies (213)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	UOK101_KIDNEY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-214	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	1.23752779560019	none		OGT_1_10111	Context-specific genetic dependencies (214)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	VCAP_PROSTATE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-215	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.465391575380833	none		OGT_1_10111	Context-specific genetic dependencies (215)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	YKG1_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-216	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.266319916478415	none		OGT_1_10111	Context-specific genetic dependencies (216)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	ZR7530_BREAST	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-22	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.237660851960714	none		OGT_1_10111	Context-specific genetic dependencies (22)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	CAL51_BREAST	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-23	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.258298365934612	none		OGT_1_10111	Context-specific genetic dependencies (23)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	CALU1_LUNG	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-24	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.938743087230443	none		OGT_1_10111	Context-specific genetic dependencies (24)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	CAOV3_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-25	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.317673067964139	none		OGT_1_10111	Context-specific genetic dependencies (25)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	CAOV4_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-26	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.327380093862148	none		OGT_1_10111	Context-specific genetic dependencies (26)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	CAS1_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-27	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-1.05133023589935	none		OGT_1_10111	Context-specific genetic dependencies (27)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	CFPAC1_PANCREAS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-28	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.789021413506839	none		OGT_1_10111	Context-specific genetic dependencies (28)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	CH157MN_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-29	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.240960991844045	none		OGT_1_10111	Context-specific genetic dependencies (29)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	COLO205_LARGE_INTESTINE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-3	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.600690267210346	none		OGT_1_10111	Context-specific genetic dependencies (3)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	786O_KIDNEY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-30	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.387199826802713	none		OGT_1_10111	Context-specific genetic dependencies (30)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	COLO704_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-31	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.0610310814537893	none		OGT_1_10111	Context-specific genetic dependencies (31)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	COLO741_SKIN	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-32	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.119152343048862	none		OGT_1_10111	Context-specific genetic dependencies (32)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	COLO783_SKIN	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-33	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	1.07259238872438	none		OGT_1_10111	Context-specific genetic dependencies (33)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	CORL23_LUNG	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-34	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-1.89134244922709	Decreased shRNA abundance (Z-score < -2)		OGT_1_10111	Context-specific genetic dependencies (34)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	COV362_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-35	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	1.23762257727754	none		OGT_1_10111	Context-specific genetic dependencies (35)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	COV434_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-36	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.00642143788595629	none		OGT_1_10111	Context-specific genetic dependencies (36)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	COV504_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-37	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.561979729774199	none		OGT_1_10111	Context-specific genetic dependencies (37)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	COV644_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-38	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.0122271423549827	none		OGT_1_10111	Context-specific genetic dependencies (38)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	DBTRG05MG_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-39	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.569099464950403	none		OGT_1_10111	Context-specific genetic dependencies (39)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	DKMG_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-4	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.370811536650942	none		OGT_1_10111	Context-specific genetic dependencies (4)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	A1207_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-40	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.614408889470133	none		OGT_1_10111	Context-specific genetic dependencies (40)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	DLD1_LARGE_INTESTINE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-41	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-2.56504866387758	Decreased shRNA abundance (Z-score < -2)		OGT_1_10111	Context-specific genetic dependencies (41)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	EFE184_ENDOMETRIUM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-42	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.534962517127988	none		OGT_1_10111	Context-specific genetic dependencies (42)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	EFM19_BREAST	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-43	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.494105118086345	none		OGT_1_10111	Context-specific genetic dependencies (43)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	EFO21_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-44	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.194869815274617	none		OGT_1_10111	Context-specific genetic dependencies (44)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	EFO27_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-45	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.191888407479886	none		OGT_1_10111	Context-specific genetic dependencies (45)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	EW8_BONE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-46	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.228148097452619	none		OGT_1_10111	Context-specific genetic dependencies (46)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	EWS502_BONE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-47	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.352496713589228	none		OGT_1_10111	Context-specific genetic dependencies (47)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	F36P_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-48	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	1.02216784060059	none		OGT_1_10111	Context-specific genetic dependencies (48)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	GB1_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-49	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.565275615790848	none		OGT_1_10111	Context-specific genetic dependencies (49)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	GP2D_LARGE_INTESTINE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-5	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.756221492299128	none		OGT_1_10111	Context-specific genetic dependencies (5)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	A172_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-50	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.385625756550531	none		OGT_1_10111	Context-specific genetic dependencies (50)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	HCC1187_BREAST	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-51	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.996180196445184	none		OGT_1_10111	Context-specific genetic dependencies (51)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	HCC1395_BREAST	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-52	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.724580027792469	none		OGT_1_10111	Context-specific genetic dependencies (52)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	HCC1954_BREAST	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-53	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.565170526879511	none		OGT_1_10111	Context-specific genetic dependencies (53)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	HCC2218_BREAST	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-54	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.220253089578042	none		OGT_1_10111	Context-specific genetic dependencies (54)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	HCC2814_LUNG	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-55	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.430810893661287	none		OGT_1_10111	Context-specific genetic dependencies (55)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	HCC364_LUNG	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-56	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.194891392681569	none		OGT_1_10111	Context-specific genetic dependencies (56)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	HCC44_LUNG	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-57	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-1.05577619066686	none		OGT_1_10111	Context-specific genetic dependencies (57)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	HCC70_BREAST	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-58	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.159810830000098	none		OGT_1_10111	Context-specific genetic dependencies (58)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	HCC827GR5_LUNG	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-59	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.0544526400885077	none		OGT_1_10111	Context-specific genetic dependencies (59)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	HCC827_LUNG	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-6	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.309949393960339	none		OGT_1_10111	Context-specific genetic dependencies (6)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	A204_SOFT_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-60	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.613668391568944	none		OGT_1_10111	Context-specific genetic dependencies (60)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	HCT116_LARGE_INTESTINE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-61	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.310956113102157	none		OGT_1_10111	Context-specific genetic dependencies (61)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	HEC1A_ENDOMETRIUM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-62	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-1.05088819811901	none		OGT_1_10111	Context-specific genetic dependencies (62)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	HEYA8_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-63	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.657412707165141	none		OGT_1_10111	Context-specific genetic dependencies (63)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	HL60_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-64	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.573799048201743	none		OGT_1_10111	Context-specific genetic dependencies (64)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	HLF_LIVER	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-65	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.346857961431812	none		OGT_1_10111	Context-specific genetic dependencies (65)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	HNT34_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-66	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.228004580248714	none		OGT_1_10111	Context-specific genetic dependencies (66)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	HPAC_PANCREAS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-67	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.112967188346191	none		OGT_1_10111	Context-specific genetic dependencies (67)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	HPAFII_PANCREAS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-68	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.0252091156552775	none		OGT_1_10111	Context-specific genetic dependencies (68)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	HS683_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-69	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	1.4140864361915	none		OGT_1_10111	Context-specific genetic dependencies (69)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	HS766T_PANCREAS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-7	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-1.93751155241053	Decreased shRNA abundance (Z-score < -2)		OGT_1_10111	Context-specific genetic dependencies (7)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	A2058_SKIN	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-70	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.197263565860687	none		OGT_1_10111	Context-specific genetic dependencies (70)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	HS944T_SKIN	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-71	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-1.40286277303144	none		OGT_1_10111	Context-specific genetic dependencies (71)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	HT1197_URINARY_TRACT	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-72	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.624918558310904	none		OGT_1_10111	Context-specific genetic dependencies (72)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	HT29_LARGE_INTESTINE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-73	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.157182863035706	none		OGT_1_10111	Context-specific genetic dependencies (73)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	HT55_LARGE_INTESTINE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-74	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.166925228004668	none		OGT_1_10111	Context-specific genetic dependencies (74)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	HUG1N_STOMACH	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-75	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	1.13127298526357	none		OGT_1_10111	Context-specific genetic dependencies (75)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	HUTU80_SMALL_INTESTINE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-76	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.451292510642518	none		OGT_1_10111	Context-specific genetic dependencies (76)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	IGR39_SKIN	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-77	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.537053458586679	none		OGT_1_10111	Context-specific genetic dependencies (77)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	IGROV1_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-78	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.625005665566644	none		OGT_1_10111	Context-specific genetic dependencies (78)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	IOMMLEE_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-79	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.438580839239392	none		OGT_1_10111	Context-specific genetic dependencies (79)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	JHESOAD1_OESOPHAGUS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-8	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.352488598594803	none		OGT_1_10111	Context-specific genetic dependencies (8)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	A549_LUNG	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-80	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.425520323376094	none		OGT_1_10111	Context-specific genetic dependencies (80)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	JHOC5_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-81	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.810544471145603	none		OGT_1_10111	Context-specific genetic dependencies (81)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	JHOM1_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-82	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-1.87068041622779	Decreased shRNA abundance (Z-score < -2)		OGT_1_10111	Context-specific genetic dependencies (82)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	JJN3_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-83	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.358569456348784	none		OGT_1_10111	Context-specific genetic dependencies (83)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	K562_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-84	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.835712071889707	none		OGT_1_10111	Context-specific genetic dependencies (84)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	KALS1_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-85	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.546867344006498	none		OGT_1_10111	Context-specific genetic dependencies (85)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	KASUMI1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-86	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.460083225013043	none		OGT_1_10111	Context-specific genetic dependencies (86)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	KM12_LARGE_INTESTINE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-87	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.371546494572124	none		OGT_1_10111	Context-specific genetic dependencies (87)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	KMS12BM_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-88	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.892712968186658	none		OGT_1_10111	Context-specific genetic dependencies (88)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	KNS60_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-89	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.795709474679811	none		OGT_1_10111	Context-specific genetic dependencies (89)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	KNS81_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-9	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.0991313182172804	none		OGT_1_10111	Context-specific genetic dependencies (9)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	A673_BONE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-90	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.108916496340434	none		OGT_1_10111	Context-specific genetic dependencies (90)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	KP1NL_PANCREAS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-91	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.0158791009369576	none		OGT_1_10111	Context-specific genetic dependencies (91)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	KP2_PANCREAS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-92	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.772329040069127	none		OGT_1_10111	Context-specific genetic dependencies (92)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	KP4_PANCREAS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-93	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-1.34044299466028	none		OGT_1_10111	Context-specific genetic dependencies (93)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	KURAMOCHI_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-94	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.34554820683368	none		OGT_1_10111	Context-specific genetic dependencies (94)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	KYSE150_OESOPHAGUS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-95	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.368678700106443	none		OGT_1_10111	Context-specific genetic dependencies (95)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	KYSE30_OESOPHAGUS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-96	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.530471721092295	none		OGT_1_10111	Context-specific genetic dependencies (96)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	KYSE450_OESOPHAGUS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-97	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	0.460368300171954	none		OGT_1_10111	Context-specific genetic dependencies (97)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	KYSE510_OESOPHAGUS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-98	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.618439740463264	none		OGT_1_10111	Context-specific genetic dependencies (98)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	L33_PANCREAS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-99	8473		OGT	TRCN0000035065, TRCN0000286199, TRCN0000286200, TRCN0000286201	-0.278515188984977	none		OGT_1_10111	Context-specific genetic dependencies (99)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	L363_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
	8473	8473	OGT		0	none
GR00371-A-1	8473	8473	OGT		1.77284260537	Increased Nanog expression		Ambion	Nanog expression in absence of bFGF and TGFbeta	Deterministic Restriction on Pluripotent State Dissolution by Cell-Cycle Pathways	Gonzales et al.	2015	26232226	Cell line	NANOG-GFP H1 hESC	NANOG expression	Fluorescence	Dharmacon and Ambion	Selected genes	siRNA	Z-score	>1,25 OR >1,5 [in at least two replicates]	Z-score shown is an average of the z-scores from the three replicates performed for each gene. In the "Comment" field, the siRNA library used for each particular gene is noted.
GR00371-A-2	8473	OGT	8473		0.731584485114	none		Ambion	Nanog expression in presence of TGFbeta inhibitor	Deterministic Restriction on Pluripotent State Dissolution by Cell-Cycle Pathways	Gonzales et al.	2015	26232226	Cell line	NANOG-GFP H1 hESC	NANOG expression	Fluorescence	Dharmacon and Ambion	Selected genes	siRNA	Z-score	>1,25 OR >1,5 [in at least two replicates]	Z-score shown is an average of the z-scores from the three replicates performed for each gene. In the "Comment" field, the siRNA library used for each particular gene is noted.
GR00371-A-3	8473	8473	OGT		1.11230217206	none		Ambion	Nanog expression in presence of MEK inhibitor	Deterministic Restriction on Pluripotent State Dissolution by Cell-Cycle Pathways	Gonzales et al.	2015	26232226	Cell line	NANOG-GFP H1 hESC	NANOG expression	Fluorescence	Dharmacon and Ambion	Selected genes	siRNA	Z-score	>1,25 OR >1,5 [in at least two replicates]	Z-score shown is an average of the z-scores from the three replicates performed for each gene. In the "Comment" field, the siRNA library used for each particular gene is noted.
GR00371-A-4	8473	8473	OGT		0.722258461538	none		Ambion	Nanog expression in presence of PI3K inhibitor	Deterministic Restriction on Pluripotent State Dissolution by Cell-Cycle Pathways	Gonzales et al.	2015	26232226	Cell line	NANOG-GFP H1 hESC	NANOG expression	Fluorescence	Dharmacon and Ambion	Selected genes	siRNA	Z-score	>1,25 OR >1,5 [in at least two replicates]	Z-score shown is an average of the z-scores from the three replicates performed for each gene. In the "Comment" field, the siRNA library used for each particular gene is noted.
GR00371-A-5	8473	8473	OGT		-1.28271180938	none		Ambion	Nanog expression in presence of retinoic acid	Deterministic Restriction on Pluripotent State Dissolution by Cell-Cycle Pathways	Gonzales et al.	2015	26232226	Cell line	NANOG-GFP H1 hESC	NANOG expression	Fluorescence	Dharmacon and Ambion	Selected genes	siRNA	Z-score	>1,25 OR >1,5 [in at least two replicates]	Z-score shown is an average of the z-scores from the three replicates performed for each gene. In the "Comment" field, the siRNA library used for each particular gene is noted.
GR00376-A-1	8473	8473	OGT		0.335097857	none			Mitigators of SS1P-induced immunotoxicity	Whole-genome RNAi screen highlights components of the endoplasmic reticulum/Golgi as a source of resistance to immunotoxin-mediated cytotoxicity	Pasetto et al.	2015	25713356	Cell line	KB cells	Viability	Luminescence	Ambion Silencer Select Version 4	Genome-wide	siRNA	RSA P-value	<0.001	SS1P was applied in a "high dose", â‰ˆEC90, 13 ng/ml. Cutoff was derived from data submitted to Pubchem (ID 1117281). Reagent sequences but no ID
GR00376-A-2	8473	8473	OGT		0.123776292	none			Sensitizers of SS1P-induced immunotoxicity	Whole-genome RNAi screen highlights components of the endoplasmic reticulum/Golgi as a source of resistance to immunotoxin-mediated cytotoxicity	Pasetto et al.	2015	25713356	Cell line	KB cells	Viability	Luminescence	Ambion Silencer Select Version 4	Genome-wide	siRNA	RSA P-value	<0.001	SS1P was applied in a "low dose", â‰ˆEC30, 3 ng/ml. Cutoff was derived from data submitted to PubChem (ID 1117281). Reagent sequences but no ID
GR00378-A	8473		OGT		-1.403262082	none			Poliovirus vaccine production	Engineering Enhanced Vaccine Cell Lines To Eradicate Vaccine-Preventable Diseases: the Polio End Game	van der Sanden et al.	2015	26581994	Cell line	HEp-2C	Infection with Attenuated Poliovirus	ELISA	Dharmacon	Genome-wide	siRNA	Z-score	>	For infection, a single lot of the attenuated Sabin type 2 poliovirus was used for the screen. Gene IDs were not provided, only the gene name/symbol
	8473	NM_181672	OGT		44.251	none
GR00386-A-1	8473	8473	OGT		71.5404792036368	none			NOD2 stimulation by MDP	A genome-wide small interfering RNA (siRNA) screen reveals nuclear factor-ÎºB (NF-ÎºB)-independent regulators of NOD2-induced interleukin-8 (IL-8) secretion.	Warner et al.	2014	25170077	Cell line	HEK293 stably expressing NOD2	Viability	Luminescence	Dharmacon	Genome-wide	siRNA	Percentage growth	Decreased: <70, increased: >120	Reagent IDs not provided
GR00386-A-2	8473	8473	OGT		-24.2	none			MDP-induced IL-8 secretion	A genome-wide small interfering RNA (siRNA) screen reveals nuclear factor-ÎºB (NF-ÎºB)-independent regulators of NOD2-induced interleukin-8 (IL-8) secretion.	Warner et al.	2014	25170077	Cell line	HEK293 stably expressing NOD2	IL-8 secretion	ELISA	Dharmacon	Genome-wide	siRNA	Percent inhibition of IL-8 secretion	Increased: <-300, Decreased: >60	Concentration of IL-8 was measured from cell supernatants by sandwich ELISA. IL-8 values (pg/ml) were normalized to IL-8 secreted in cells treated with RIPK2-specific siRNA (100% inhibition) and non-targeting siRNA (0% inhibition). Secondary validating screen assessed 554 genes whose silencing affected MDP-induced IL-8 secretion in the primary screen. Final validated IL-8 regulators (positive or negative) are listed in the comments column. Reagent IDs not provided