Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 10133
  • Symbol: OPTN
  • Description: optineurin

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
10133 GO:0001920 IMP involved_in negative regulation of receptor recycling 22854040 Process
10133 GO:0007030 IMP involved_in Golgi organization 15837803 Process
10133 GO:0010508 IDA involved_in positive regulation of autophagy 21617041 Process
10133 GO:0034067 IMP involved_in protein localization to Golgi apparatus 15837803 Process
10133 GO:0034620 IMP involved_in cellular response to unfolded protein 27534431 Process
10133 GO:0043001 IMP involved_in Golgi to plasma membrane protein transport 15837803 Process
10133 GO:0050829 IMP involved_in defense response to Gram-negative bacterium 21617041 Process
10133 GO:0061734 IMP involved_in parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization 25294927 Process
10133 GO:0090161 IDA involved_in Golgi ribbon formation 15837803 Process
10133 GO:0090161 IMP involved_in Golgi ribbon formation 27534431 Process
10133 GO:1904417 IMP involved_in positive regulation of xenophagy 21617041 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
10133 GO:0005515 IPI enables protein binding 15837803,16189514,17500595,17646400,18307994,19805065,20174559..... Function
10133 GO:0030674 IPI enables protein-macromolecule adaptor activity 25803835 Function
10133 GO:0031593 IDA enables polyubiquitin modification-dependent protein binding 21617041 Function
10133 GO:0042802 IPI enables identical protein binding 23414517,24983867,25416956,25910212,26871637,32296183..... Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
10133 GO:0005794 IDA located_in Golgi apparatus 15837803,27534431 Component
10133 GO:0005802 IDA located_in trans-Golgi network 20174559 Component
10133 GO:0005829 IDA located_in cytosol Component