Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 1029
  • Symbol: CDKN2A
  • Description: cyclin dependent kinase inhibitor 2A

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
1029 GO:0001953 IMP involved_in negative regulation of cell-matrix adhesion 10205165 Process
1029 GO:0007265 IEP involved_in Ras protein signal transduction 9054499 Process
1029 GO:0008285 IDA involved_in negative regulation of cell population proliferation 15149599 Process
1029 GO:0008285 IMP involved_in negative regulation of cell population proliferation 7603984,16243918,16901784 Process
1029 GO:0030308 IDA involved_in negative regulation of cell growth 10208428 Process
1029 GO:0032088 IDA involved_in negative regulation of NF-kappaB transcription factor activity 10353611 Process
1029 GO:0042326 IDA involved_in negative regulation of phosphorylation 8259215,10208428 Process
1029 GO:0045736 IDA acts_upstream_of_or_within negative regulation of cyclin-dependent protein serine/threonine kinase activity 7739547 Process
1029 GO:0045736 IDA involved_in negative regulation of cyclin-dependent protein serine/threonine kinase activity 8259215 Process
1029 GO:0045892 IMP involved_in negative regulation of DNA-templated transcription 16901784 Process
1029 GO:0051726 IDA involved_in regulation of cell cycle 15149599 Process
1029 GO:0051726 IMP involved_in regulation of cell cycle 16243918 Process
1029 GO:0090398 IMP involved_in cellular senescence 16243918 Process
1029 GO:0090399 IMP involved_in replicative senescence 14720514 Process
1029 GO:2000045 IDA involved_in regulation of G1/S transition of mitotic cell cycle 10208428 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
1029 GO:0003723 HDA enables RNA binding 22681889 Function
1029 GO:0004861 IDA enables cyclin-dependent protein serine/threonine kinase inhibitor activity 7739547,8259215 Function
1029 GO:0005515 IPI enables protein binding 9751050,11278317,15232106,17517622,17658461,17909018,17955473,..... Function
1029 GO:0019901 IPI enables protein kinase binding 8259215 Function
1029 GO:0051059 IDA enables NF-kappaB binding 10353611 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
1029 GO:0005634 IDA located_in nucleus 16243918 Component
1029 GO:0005737 IDA located_in cytoplasm 16243918 Component
1029 GO:0035985 IDA part_of senescence-associated heterochromatin focus 16901784 Component