Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 10558
  • Symbol: SPTLC1
  • Description: serine palmitoyltransferase long chain base subunit 1

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
10558 GO:0004758 IDA contributes_to serine C-palmitoyltransferase activity 25332431,25691431 Function
10558 GO:0004758 IDA enables serine C-palmitoyltransferase activity 19416851 Function
10558 GO:0005515 IPI enables protein binding 19416851,20182505,33558761 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
10558 GO:0005783 IDA located_in endoplasmic reticulum Component
10558 GO:0017059 IDA part_of serine C-palmitoyltransferase complex 19416851 Component
10558 GO:0017059 IPI part_of serine C-palmitoyltransferase complex 19416851,33558761 Component
10558 GO:0035339 IDA part_of SPOTS complex 20182505,25691431 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
10558 GO:0030148 IDA acts_upstream_of_or_within sphingolipid biosynthetic process 25332431 Process
10558 GO:0046512 IDA involved_in sphingosine biosynthetic process 19416851,33558761 Process
10558 GO:0046513 IDA acts_upstream_of_or_within ceramide biosynthetic process 25691431 Process
10558 GO:1904504 IDA acts_upstream_of_or_within positive regulation of lipophagy 25332431 Process