Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 10594
  • Symbol: PRPF8
  • Description: pre-mRNA processing factor 8

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
10594 GO:0000244 IDA involved_in spliceosomal tri-snRNP complex assembly 20595234 Process
10594 GO:0000398 IDA involved_in mRNA splicing, via spliceosome 28781166,29301961 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
10594 GO:0003723 HDA enables RNA binding 22658674,22681889 Function
10594 GO:0005515 IPI enables protein binding 9774689,16723661,18951082,20696395,22365833,22720776,23704370,..... Function
10594 GO:0070530 IDA enables K63-linked polyubiquitin modification-dependent protein binding 20595234 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
10594 GO:0005634 IDA located_in nucleus 22720776,28781166,29301961 Component
10594 GO:0016020 HDA located_in membrane 19946888 Component
10594 GO:0046540 IDA part_of U4/U6 x U5 tri-snRNP complex 23793891 Component
10594 GO:0046540 IPI part_of U4/U6 x U5 tri-snRNP complex 30975767 Component
10594 GO:0071005 IDA part_of U2-type precatalytic spliceosome 28781166,29361316,30315277 Component
10594 GO:0071006 IDA part_of U2-type catalytic step 1 spliceosome 29301961 Component
10594 GO:0071007 IDA part_of U2-type catalytic step 2 spliceosome 28076346 Component
10594 GO:0071013 IDA part_of catalytic step 2 spliceosome 11991638 Component