Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 10664
  • Symbol: CTCF
  • Description: CCCTC-binding factor

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
10664 GO:0000122 IDA involved_in negative regulation of transcription by RNA polymerase II 8649389 Process
10664 GO:0008285 IMP involved_in negative regulation of cell population proliferation 28319062 Process
10664 GO:0010628 IMP involved_in positive regulation of gene expression 18347100 Process
10664 GO:0040029 IMP involved_in epigenetic regulation of gene expression 16815976 Process
10664 GO:0045892 IDA involved_in negative regulation of DNA-templated transcription 8649389,18413740 Process
10664 GO:0045893 IDA involved_in positive regulation of DNA-templated transcription 9407128 Process
10664 GO:0045893 IMP involved_in positive regulation of DNA-templated transcription 19322193 Process
10664 GO:0071459 IMP involved_in protein localization to chromosome, centromeric region 26321640 Process
10664 GO:0071514 IDA involved_in genomic imprinting 17827499 Process
10664 GO:0140588 IDA involved_in chromatin looping 18654629 Process

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
10664 GO:0000775 IDA located_in chromosome, centromeric region 18550811,26321640 Component
10664 GO:0000793 IDA located_in condensed chromosome 16107875 Component
10664 GO:0005634 IDA located_in nucleus 9407128,28319062,31547883 Component
10664 GO:0005654 IDA located_in nucleoplasm 16107875,16595548 Component
10664 GO:0005730 IDA located_in nucleolus 16595548 Component

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
10664 GO:0000976 IDA enables transcription cis-regulatory region binding 18413740 Function
10664 GO:0000978 IDA enables RNA polymerase II cis-regulatory region sequence-specific DNA binding 8649389 Function
10664 GO:0001221 IPI enables transcription coregulator binding 31547883 Function
10664 GO:0001227 IDA enables DNA-binding transcription repressor activity, RNA polymerase II-specific 8649389 Function
10664 GO:0003700 IDA enables DNA-binding transcription factor activity 8649389,9591631 Function
10664 GO:0005515 IPI enables protein binding 19505873,19536159,24725430,24937458,25416956,26321640,32296183..... Function
10664 GO:0043035 IDA enables chromatin insulator sequence binding 17827499 Function
10664 GO:0043565 IDA enables sequence-specific DNA binding 17827499 Function