Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 10891
  • Symbol: PPARGC1A
  • Description: PPARG coactivator 1 alpha

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
10891 GO:0003713 IDA enables transcription coactivator activity 16753578,19651776,21376232,27471003 Function
10891 GO:0005515 IPI enables protein binding 12522104,15337744,17050673,18063693,18441008,19171140,19846556..... Function
10891 GO:0016922 IPI enables nuclear receptor binding 18798693 Function
10891 GO:0030374 IDA enables nuclear receptor coactivator activity 16488887 Function
10891 GO:0031625 IPI enables ubiquitin protein ligase binding 22064484 Function
10891 GO:0043565 IDA enables sequence-specific DNA binding 23836911 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
10891 GO:0005634 IDA is_active_in nucleus 10713165 Component
10891 GO:0005634 IDA located_in nucleus 23836911 Component
10891 GO:0005654 IDA located_in nucleoplasm Component
10891 GO:0005829 IDA located_in cytosol Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
10891 GO:0006094 IDA involved_in gluconeogenesis 16753578,23142079 Process
10891 GO:0006355 IDA acts_upstream_of_or_within regulation of DNA-templated transcription 27471003 Process
10891 GO:0006355 IDA involved_in regulation of DNA-templated transcription 23836911 Process
10891 GO:0010628 IDA involved_in positive regulation of gene expression 23525105 Process
10891 GO:0010628 IMP involved_in positive regulation of gene expression 29182484 Process
10891 GO:0010822 IMP involved_in positive regulation of mitochondrion organization 25118933 Process
10891 GO:0045893 IDA involved_in positive regulation of DNA-templated transcription 16488887,19651776 Process
10891 GO:0045944 IDA involved_in positive regulation of transcription by RNA polymerase II 21376232 Process
10891 GO:0048662 IMP acts_upstream_of negative regulation of smooth muscle cell proliferation 29182484 Process
10891 GO:0051091 IDA involved_in positive regulation of DNA-binding transcription factor activity 19651776 Process