Gene Ontology

Gene Info

• Species: Mouse (Mus musculus)
• GeneID: 109305
• Symbol: Orai1
• Description: ORAI calcium release-activated calcium modulator 1

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
109305	GO:0002115	IGI	acts_upstream_of_or_within	store-operated calcium entry	17343823,20418871	Process
109305	GO:0007200	IMP	involved_in	phospholipase C-activating G protein-coupled receptor signaling pathway	31664108	Process
109305	GO:0032024	IMP	involved_in	positive regulation of insulin secretion	31664108	Process
109305	GO:0061180	IMP	acts_upstream_of_or_within	mammary gland epithelium development	23840669	Process
109305	GO:0070509	IDA	acts_upstream_of_or_within	calcium ion import	23840669	Process
109305	GO:0099105	IMP	involved_in	ion channel modulating, G protein-coupled receptor signaling pathway	31664108	Process
109305	GO:1990806	IMP	involved_in	ligand-gated ion channel signaling pathway	31664108	Process

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
109305	GO:0005515	IPI	enables	protein binding	17343823,20418871,23840669	Function
109305	GO:0015279	IMP	enables	store-operated calcium channel activity	31664108	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
109305	GO:0005886	IDA	is_active_in	plasma membrane	17343823	Component
109305	GO:0016020	IDA	located_in	membrane	17343823	Component
109305	GO:0016323	IDA	located_in	basolateral plasma membrane	23840669	Component
109305	GO:0032991	IPI	part_of	protein-containing complex	20418871	Component