Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 10935
  • Symbol: PRDX3
  • Description: peroxiredoxin 3

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
10935 GO:0005515 IPI enables protein binding 12492477,15750338,17060495,18205602,20873783,21850687,24459295..... Function
10935 GO:0008379 IDA enables thioredoxin peroxidase activity 21850687 Function
10935 GO:0019901 IPI enables protein kinase binding 21850687 Function
10935 GO:0042802 IPI enables identical protein binding 21988832,25914057 Function
10935 GO:0043027 IMP enables cysteine-type endopeptidase inhibitor activity involved in apoptotic process 18262354 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
10935 GO:0005654 IDA located_in nucleoplasm Component
10935 GO:0005737 IDA located_in cytoplasm 18205602 Component
10935 GO:0005739 IDA located_in mitochondrion 17893648,18262354,21850687 Component
10935 GO:0005769 IDA located_in early endosome 15750338 Component
10935 GO:0005829 IDA located_in cytosol 21850687 Component
10935 GO:0005886 IDA located_in plasma membrane Component
10935 GO:0032991 IDA part_of protein-containing complex 20873783 Component
10935 GO:0043231 IDA located_in intracellular membrane-bounded organelle Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
10935 GO:0006979 IMP involved_in response to oxidative stress 18195003 Process
10935 GO:0007005 IMP involved_in mitochondrion organization 12011429 Process
10935 GO:0008284 IDA involved_in positive regulation of cell population proliferation 12011429 Process
10935 GO:0018171 IDA involved_in peptidyl-cysteine oxidation 21850687 Process
10935 GO:0033673 IDA involved_in negative regulation of kinase activity 18205602 Process
10935 GO:0034599 IDA involved_in cellular response to oxidative stress 21850687 Process
10935 GO:0034614 IMP involved_in cellular response to reactive oxygen species 18262354 Process
10935 GO:0042542 IDA involved_in response to hydrogen peroxide 17893648 Process
10935 GO:0042744 IDA acts_upstream_of_or_within hydrogen peroxide catabolic process 7733872 Process
10935 GO:0042744 IMP involved_in hydrogen peroxide catabolic process 18195003 Process
10935 GO:0043066 IDA involved_in negative regulation of apoptotic process 21850687 Process
10935 GO:0043066 IMP involved_in negative regulation of apoptotic process 18262354 Process
10935 GO:0051092 IDA involved_in positive regulation of NF-kappaB transcription factor activity 12492477 Process
10935 GO:0051881 IMP involved_in regulation of mitochondrial membrane potential 12011429 Process