Gene Ontology

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 11277
• Symbol: TREX1
• Description: three prime repair exonuclease 1

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
11277	GO:0005789	IDA	located_in	endoplasmic reticulum membrane	33476576	Component
11277	GO:0005829	IDA	located_in	cytosol		Component

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
11277	GO:0008296	IDA	enables	3'-5'-DNA exonuclease activity	33476576	Function
11277	GO:0008311	IDA	enables	double-stranded DNA 3'-5' DNA exonuclease activity	33476576	Function
11277	GO:0008408	IDA	enables	3'-5' exonuclease activity	10391904	Function
11277	GO:0032405	IDA	enables	MutLalpha complex binding		Function
11277	GO:0032407	IDA	enables	MutSalpha complex binding		Function

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
11277	GO:0045824	IDA	involved_in	negative regulation of innate immune response	33476576	Process