Gene Ontology

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 11352
  • Symbol: Abl2
  • Description: ABL proto-oncogene 2, non-receptor tyrosine kinase

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
11352 GO:0000287 IDA enables magnesium ion binding 12748290 Function
11352 GO:0004713 IDA enables protein tyrosine kinase activity 12748290,15084284,18827006,19414610,23100514 Function
11352 GO:0004713 IGI enables protein tyrosine kinase activity 18827006,20837657 Function
11352 GO:0004713 IMP enables protein tyrosine kinase activity 15084284 Function
11352 GO:0005515 IPI enables protein binding 19414610,22357865 Function
11352 GO:0030145 IDA enables manganese ion binding 12748290 Function

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
11352 GO:0001843 IGI acts_upstream_of_or_within neural tube closure 9883720 Process
11352 GO:0002118 IMP acts_upstream_of_or_within aggressive behavior 9883720 Process
11352 GO:0006468 IDA involved_in protein phosphorylation 12748290 Process
11352 GO:0006909 IGI acts_upstream_of_or_within phagocytosis 23100514 Process
11352 GO:0006909 IMP acts_upstream_of_or_within phagocytosis 22665498 Process
11352 GO:0006930 IGI acts_upstream_of_or_within substrate-dependent cell migration, cell extension 19414610 Process
11352 GO:0007015 IDA acts_upstream_of_or_within actin filament organization 11752434 Process
11352 GO:0007173 IGI acts_upstream_of_or_within epidermal growth factor receptor signaling pathway 18827006 Process
11352 GO:0007249 IGI acts_upstream_of I-kappaB kinase/NF-kappaB signaling 18025176 Process
11352 GO:0007266 IGI acts_upstream_of Rho protein signal transduction 23595732 Process
11352 GO:0007612 IMP acts_upstream_of_or_within learning 19805386 Process
11352 GO:0007628 IMP acts_upstream_of_or_within adult walking behavior 9883720 Process
11352 GO:0008104 IMP acts_upstream_of_or_within protein localization 23365224 Process
11352 GO:0008542 IGI acts_upstream_of_or_within visual learning 22357865 Process
11352 GO:0009791 IGI acts_upstream_of_or_within post-embryonic development 9883720 Process
11352 GO:0010976 IGI acts_upstream_of_or_within positive regulation of neuron projection development 15084284 Process
11352 GO:0016322 IMP acts_upstream_of_or_within neuron remodeling 19805386 Process
11352 GO:0018108 IDA involved_in peptidyl-tyrosine phosphorylation 12748290 Process
11352 GO:0021587 IGI acts_upstream_of_or_within cerebellum morphogenesis 20980600 Process
11352 GO:0022408 IGI acts_upstream_of_or_within negative regulation of cell-cell adhesion 24367707 Process
11352 GO:0022414 IMP acts_upstream_of_or_within reproductive process 9883720 Process
11352 GO:0030036 IDA involved_in actin cytoskeleton organization 11752434 Process
11352 GO:0030036 IGI acts_upstream_of_or_within actin cytoskeleton organization 9883720 Process
11352 GO:0030182 IGI acts_upstream_of_or_within neuron differentiation 9883720 Process
11352 GO:0031223 IMP acts_upstream_of_or_within auditory behavior 9883720 Process
11352 GO:0032092 IMP acts_upstream_of_or_within positive regulation of protein binding 15084284 Process
11352 GO:0032729 IGI acts_upstream_of_or_within positive regulation of type II interferon production 18025176 Process
11352 GO:0032743 IGI acts_upstream_of_or_within positive regulation of interleukin-2 production 18025176 Process
11352 GO:0035024 IGI acts_upstream_of_or_within negative regulation of Rho protein signal transduction 15084284,22357865,23595732 Process
11352 GO:0035264 IMP acts_upstream_of_or_within multicellular organism growth 9883720 Process
11352 GO:0035640 IGI acts_upstream_of_or_within exploration behavior 23595732 Process
11352 GO:0043123 IGI acts_upstream_of_or_within positive regulation of I-kappaB kinase/NF-kappaB signaling 18025176 Process
11352 GO:0046632 IGI acts_upstream_of_or_within alpha-beta T cell differentiation 18025176 Process
11352 GO:0048008 IGI acts_upstream_of_or_within platelet-derived growth factor receptor signaling pathway 18827006 Process
11352 GO:0048813 IGI acts_upstream_of_or_within dendrite morphogenesis 22357865,23365224 Process
11352 GO:0048813 IMP acts_upstream_of_or_within dendrite morphogenesis 23365224 Process
11352 GO:0050885 IGI acts_upstream_of_or_within neuromuscular process controlling balance 20980600 Process
11352 GO:0050885 IMP acts_upstream_of_or_within neuromuscular process controlling balance 9883720 Process
11352 GO:0051017 IDA acts_upstream_of_or_within actin filament bundle assembly 11752434 Process
11352 GO:0051649 IGI acts_upstream_of_or_within establishment of localization in cell 23100514 Process
11352 GO:0051649 IMP acts_upstream_of_or_within establishment of localization in cell 22665498 Process
11352 GO:0060020 IGI acts_upstream_of_or_within Bergmann glial cell differentiation 20980600 Process
11352 GO:0060074 IDA involved_in synapse maturation 27335408 Process
11352 GO:0060074 IMP involved_in synapse maturation 27335408 Process
11352 GO:0060563 IGI acts_upstream_of_or_within neuroepithelial cell differentiation 9883720 Process
11352 GO:0070374 IGI acts_upstream_of_or_within positive regulation of ERK1 and ERK2 cascade 18827006 Process
11352 GO:0072359 IGI acts_upstream_of_or_within circulatory system development 9883720 Process
11352 GO:0097062 IGI acts_upstream_of_or_within dendritic spine maintenance 23365224 Process
11352 GO:0097062 IMP acts_upstream_of_or_within dendritic spine maintenance 23365224 Process
11352 GO:0098609 IGI acts_upstream_of cell-cell adhesion 24367707 Process
11352 GO:1903053 IGI acts_upstream_of_or_within regulation of extracellular matrix organization 20980600 Process
11352 GO:1903905 IMP involved_in positive regulation of establishment of T cell polarity 22810897 Process
11352 GO:1904157 IGI acts_upstream_of_or_within DN4 thymocyte differentiation 18025176 Process
11352 GO:2000096 IGI acts_upstream_of_or_within positive regulation of Wnt signaling pathway, planar cell polarity pathway 20837657 Process
11352 GO:2000352 IGI acts_upstream_of_or_within negative regulation of endothelial cell apoptotic process 23840065 Process
11352 GO:2000406 IMP involved_in positive regulation of T cell migration 22810897 Process

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
11352 GO:0001891 IDA located_in phagocytic cup 23100514 Component
11352 GO:0015629 IDA located_in actin cytoskeleton 11752434 Component
11352 GO:0030027 IDA located_in lamellipodium 19414610 Component
11352 GO:0043197 IDA located_in dendritic spine 23365224 Component
11352 GO:0098794 IDA is_active_in postsynapse 23365224 Component
11352 GO:0098794 IMP is_active_in postsynapse 23365224 Component
11352 GO:0098978 IDA is_active_in glutamatergic synapse 23365224,27335408 Component
11352 GO:0098978 IMP is_active_in glutamatergic synapse 23365224,27335408 Component