Gene Ontology

Gene Info

  • Species: Rat (Rattus norvegicus)
  • GeneID: 116647
  • Symbol: Nlgn1
  • Description: neuroligin 1

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
116647 GO:0005515 IPI enables protein binding 19730411,20543817,31801062 Function
116647 GO:0038023 IDA enables signaling receptor activity 15797875 Function
116647 GO:0042043 IPI enables neurexin family protein binding 14522992,15797875,18093522,19730411 Function
116647 GO:0042802 IPI enables identical protein binding 19730411 Function
116647 GO:0044877 IDA enables protein-containing complex binding 18093522 Function
116647 GO:0050839 IPI enables cell adhesion molecule binding 15797875,19730411 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
116647 GO:0005794 IDA located_in Golgi apparatus 15519238 Component
116647 GO:0005886 IDA located_in plasma membrane 15519238 Component
116647 GO:0009986 IDA located_in cell surface 15797875,19730411 Component
116647 GO:0030425 IDA located_in dendrite 17582332,20534458 Component
116647 GO:0032433 IDA located_in filopodium tip 19450252 Component
116647 GO:0043197 IDA located_in dendritic spine 15519238 Component
116647 GO:0043198 IDA located_in dendritic shaft 22539981 Component
116647 GO:0045202 IDA located_in synapse 9278515,17582332 Component
116647 GO:0098978 IDA is_active_in glutamatergic synapse 9927700 Component
116647 GO:0099634 IDA is_active_in postsynaptic specialization membrane 9927700 Component
116647 GO:0099634 IDA located_in postsynaptic specialization membrane 15519238,19450252 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
116647 GO:0006605 IDA involved_in protein targeting 9278515 Process
116647 GO:0007158 IDA involved_in neuron cell-cell adhesion 15797875 Process
116647 GO:0007416 IDA involved_in synapse assembly 15797875 Process
116647 GO:0016339 IDA involved_in calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules 9325340 Process
116647 GO:0031175 IGI involved_in neuron projection development 22750515 Process
116647 GO:0032230 IDA involved_in positive regulation of synaptic transmission, GABAergic 12930820 Process
116647 GO:0048489 IMP involved_in synaptic vesicle transport 19628693 Process
116647 GO:0048789 IMP involved_in cytoskeletal matrix organization at active zone 19628693 Process
116647 GO:0050804 IMP involved_in modulation of chemical synaptic transmission 25428619 Process
116647 GO:0050808 IDA acts_upstream_of_or_within synapse organization 15681343 Process
116647 GO:0051491 IDA involved_in positive regulation of filopodium assembly 12930820 Process
116647 GO:0051965 IDA involved_in positive regulation of synapse assembly 15797875,17582332 Process
116647 GO:0051968 IDA involved_in positive regulation of synaptic transmission, glutamatergic 19730411 Process
116647 GO:0051968 IMP involved_in positive regulation of synaptic transmission, glutamatergic 19628693 Process
116647 GO:0060080 IDA NOT involved_in inhibitory postsynaptic potential 17582332 Process
116647 GO:0060291 IMP involved_in long-term synaptic potentiation 23083734 Process
116647 GO:0060999 IDA involved_in positive regulation of dendritic spine development 17582332 Process
116647 GO:0060999 IMP involved_in positive regulation of dendritic spine development 15681343 Process
116647 GO:0071277 IDA involved_in cellular response to calcium ion 14522992 Process
116647 GO:0072553 IMP involved_in terminal button organization 19628693 Process
116647 GO:0097091 IDA involved_in synaptic vesicle clustering 20534458 Process
116647 GO:0097091 IMP involved_in synaptic vesicle clustering 19628693 Process
116647 GO:0097105 IDA involved_in presynaptic membrane assembly 15797875,19730411 Process
116647 GO:0097113 IMP involved_in AMPA glutamate receptor clustering 21940442 Process
116647 GO:0097114 IDA involved_in NMDA glutamate receptor clustering 19450252 Process
116647 GO:0097119 IDA involved_in postsynaptic density protein 95 clustering 19450252 Process
116647 GO:0097119 IMP involved_in postsynaptic density protein 95 clustering 12930820,19450252 Process
116647 GO:0098942 IMP involved_in retrograde trans-synaptic signaling by trans-synaptic protein complex 17237775 Process
116647 GO:0099174 EXP involved_in regulation of presynapse organization 10892652 Process
116647 GO:0099174 IDA involved_in regulation of presynapse organization 10892652 Process
116647 GO:0099174 IMP involved_in regulation of presynapse organization 10892652 Process
116647 GO:0140058 IGI involved_in neuron projection arborization 22750515 Process
116647 GO:1900029 IDA involved_in positive regulation of ruffle assembly 12930820 Process
116647 GO:1900244 IMP involved_in positive regulation of synaptic vesicle endocytosis 19628693 Process
116647 GO:1902474 IMP involved_in positive regulation of protein localization to synapse 15681343 Process
116647 GO:1902533 IDA involved_in positive regulation of intracellular signal transduction 17582332 Process
116647 GO:1905520 IDA involved_in positive regulation of presynaptic active zone assembly 15797875 Process
116647 GO:2000302 IMP involved_in positive regulation of synaptic vesicle exocytosis 19628693 Process
116647 GO:2000310 IDA involved_in regulation of NMDA receptor activity 17582332 Process
116647 GO:2000310 IMP involved_in regulation of NMDA receptor activity 19628693,25428619 Process
116647 GO:2000311 IDA involved_in regulation of AMPA receptor activity 17582332 Process
116647 GO:2000463 IDA involved_in positive regulation of excitatory postsynaptic potential 17582332,19730411 Process
116647 GO:2000463 IMP involved_in positive regulation of excitatory postsynaptic potential 19628693 Process