Gene Ontology

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 12005
  • Symbol: Axin1
  • Description: axin 1

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
12005 GO:0000209 IDA acts_upstream_of_or_within protein polyubiquitination 16601693 Process
12005 GO:0001701 IGI acts_upstream_of_or_within in utero embryonic development 19204372 Process
12005 GO:0001701 IMP acts_upstream_of_or_within in utero embryonic development 19204372 Process
12005 GO:0001932 IGI acts_upstream_of_or_within regulation of protein phosphorylation 14734535 Process
12005 GO:0001934 IDA acts_upstream_of_or_within positive regulation of protein phosphorylation 10330403 Process
12005 GO:0006913 IDA acts_upstream_of_or_within nucleocytoplasmic transport 14981260 Process
12005 GO:0007605 IMP acts_upstream_of_or_within sensory perception of sound 21003499 Process
12005 GO:0007628 IMP acts_upstream_of_or_within adult walking behavior Process
12005 GO:0009950 IDA acts_upstream_of_or_within dorsal/ventral axis specification 10330403 Process
12005 GO:0009953 IMP acts_upstream_of_or_within dorsal/ventral pattern formation 18316368 Process
12005 GO:0010629 IDA acts_upstream_of_or_within negative regulation of gene expression 18076571 Process
12005 GO:0010800 IDA involved_in positive regulation of peptidyl-threonine phosphorylation 11955436 Process
12005 GO:0016055 IDA acts_upstream_of_or_within Wnt signaling pathway 11113207 Process
12005 GO:0016055 IPI acts_upstream_of_or_within Wnt signaling pathway 11113207 Process
12005 GO:0020027 IMP acts_upstream_of_or_within hemoglobin metabolic process Process
12005 GO:0030163 IDA acts_upstream_of_or_within protein catabolic process 12717450 Process
12005 GO:0030178 IDA acts_upstream_of_or_within negative regulation of Wnt signaling pathway 9230313,12717450,17681137 Process
12005 GO:0030511 IDA acts_upstream_of_or_within positive regulation of transforming growth factor beta receptor signaling pathway 16601693 Process
12005 GO:0030511 IGI acts_upstream_of_or_within positive regulation of transforming growth factor beta receptor signaling pathway 16601693 Process
12005 GO:0030511 IMP acts_upstream_of_or_within positive regulation of transforming growth factor beta receptor signaling pathway 16601693 Process
12005 GO:0031122 IGI acts_upstream_of_or_within cytoplasmic microtubule organization 14734535 Process
12005 GO:0031398 IDA acts_upstream_of_or_within positive regulation of protein ubiquitination 16601693 Process
12005 GO:0031398 IGI acts_upstream_of_or_within positive regulation of protein ubiquitination 16601693 Process
12005 GO:0031398 IMP acts_upstream_of_or_within positive regulation of protein ubiquitination 16601693 Process
12005 GO:0032436 IDA acts_upstream_of_or_within positive regulation of proteasomal ubiquitin-dependent protein catabolic process 16601693 Process
12005 GO:0033138 IDA involved_in positive regulation of peptidyl-serine phosphorylation 11955436 Process
12005 GO:0034101 IMP acts_upstream_of_or_within erythrocyte homeostasis Process
12005 GO:0034244 IDA acts_upstream_of_or_within negative regulation of transcription elongation by RNA polymerase II 10318824,19204372 Process
12005 GO:0036342 IMP acts_upstream_of_or_within post-anal tail morphogenesis 12601169 Process
12005 GO:0043507 IDA acts_upstream_of_or_within positive regulation of JUN kinase activity 12878610 Process
12005 GO:0043507 IMP acts_upstream_of_or_within positive regulation of JUN kinase activity 12878610,15579909 Process
12005 GO:0045599 IDA acts_upstream_of_or_within negative regulation of fat cell differentiation 10937998 Process
12005 GO:0045860 IDA involved_in positive regulation of protein kinase activity 15526030 Process
12005 GO:0045893 IDA involved_in positive regulation of DNA-templated transcription 16601693 Process
12005 GO:0046330 IMP acts_upstream_of_or_within positive regulation of JNK cascade 18316368 Process
12005 GO:0046330 IMP involved_in positive regulation of JNK cascade 17681137 Process
12005 GO:0048318 IMP acts_upstream_of_or_within axial mesoderm development 9230313 Process
12005 GO:0048320 IMP acts_upstream_of_or_within axial mesoderm formation 9230313 Process
12005 GO:0050877 IMP acts_upstream_of_or_within nervous system process Process
12005 GO:0051248 IDA acts_upstream_of_or_within negative regulation of protein metabolic process 10330403 Process
12005 GO:0051443 IMP involved_in positive regulation of ubiquitin-protein transferase activity 16601693 Process
12005 GO:0060070 IDA acts_upstream_of_or_within canonical Wnt signaling pathway 10937998 Process
12005 GO:0060070 IMP acts_upstream_of_or_within canonical Wnt signaling pathway 19075000 Process
12005 GO:0060272 IMP acts_upstream_of_or_within embryonic skeletal joint morphogenesis Process
12005 GO:0060322 IMP acts_upstream_of_or_within head development 21344612 Process
12005 GO:0060828 IDA acts_upstream_of_or_within regulation of canonical Wnt signaling pathway 14981260 Process
12005 GO:0071514 IMP acts_upstream_of_or_within genomic imprinting 12601169 Process
12005 GO:0090090 IDA acts_upstream_of_or_within negative regulation of canonical Wnt signaling pathway 15579909,19204372 Process
12005 GO:2000060 IDA acts_upstream_of_or_within positive regulation of ubiquitin-dependent protein catabolic process 16601693 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
12005 GO:0002039 IPI enables p53 binding 15526030 Function
12005 GO:0005515 IDA enables protein binding 10318824 Function
12005 GO:0005515 IPI enables protein binding 9920888,10688669,11113207,11336703,12421363,12805222,12878610,..... Function
12005 GO:0008013 IPI enables beta-catenin binding 10318824,10330403,18632848 Function
12005 GO:0019901 IPI enables protein kinase binding 10318824,15526030,22899650 Function
12005 GO:0019904 IPI enables protein domain specific binding 15579909,17681137 Function
12005 GO:0031625 IPI enables ubiquitin protein ligase binding 16601693 Function
12005 GO:0042802 IPI enables identical protein binding 9920888,10318824,15579909,18632848 Function
12005 GO:0042803 IPI enables protein homodimerization activity 17681137 Function
12005 GO:0043621 IPI enables protein self-association 15579909 Function
12005 GO:0060090 IMP enables molecular adaptor activity 16601693 Function
12005 GO:0070411 IDA enables I-SMAD binding 16601693 Function
12005 GO:0070411 IPI enables I-SMAD binding 16601693 Function
12005 GO:0070412 IPI enables R-SMAD binding 16601693 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
12005 GO:0005737 IDA located_in cytoplasm 11113207,16601693,18606656 Component
12005 GO:0005886 IDA located_in plasma membrane 10330403,12138115,16815997 Component
12005 GO:0005938 IDA located_in cell cortex 10330403 Component
12005 GO:0015630 IDA located_in microtubule cytoskeleton 14734535 Component
12005 GO:0030877 IDA part_of beta-catenin destruction complex 10318824 Component
12005 GO:0031410 IDA located_in cytoplasmic vesicle 11113207 Component
12005 GO:0032991 IDA part_of protein-containing complex 16601693 Component
12005 GO:1990909 IDA part_of Wnt signalosome 22899650 Component