Gene Ontology

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 12168
  • Symbol: Bmpr2
  • Description: bone morphogenetic protein receptor, type II (serine/threonine kinase)

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
12168 GO:0001649 IDA involved_in osteoblast differentiation 7798324 Process
12168 GO:0001707 IMP acts_upstream_of_or_within mesoderm formation 10772805 Process
12168 GO:0001893 IMP acts_upstream_of_or_within maternal placenta development 23676498 Process
12168 GO:0001946 IMP involved_in lymphangiogenesis 19903896 Process
12168 GO:0001974 IMP involved_in blood vessel remodeling 19903896 Process
12168 GO:0003148 IMP NOT involved_in outflow tract septum morphogenesis 19409885 Process
12168 GO:0003148 IMP involved_in outflow tract septum morphogenesis 12441304 Process
12168 GO:0003151 IMP involved_in outflow tract morphogenesis 19409885 Process
12168 GO:0003176 IMP involved_in aortic valve development 12441304 Process
12168 GO:0003177 IMP involved_in pulmonary valve development 12441304 Process
12168 GO:0003181 IMP NOT involved_in atrioventricular valve morphogenesis 12441304 Process
12168 GO:0003183 IMP involved_in mitral valve morphogenesis 19409885 Process
12168 GO:0003186 IMP involved_in tricuspid valve morphogenesis 19409885 Process
12168 GO:0003197 IMP involved_in endocardial cushion development 12441304 Process
12168 GO:0003252 IMP involved_in negative regulation of cell proliferation involved in heart valve morphogenesis 19409885 Process
12168 GO:0009952 IGI acts_upstream_of_or_within anterior/posterior pattern specification 15542835 Process
12168 GO:0009952 IMP acts_upstream_of_or_within anterior/posterior pattern specification 10772805 Process
12168 GO:0014916 IMP involved_in regulation of lung blood pressure 18552156 Process
12168 GO:0030509 IDA involved_in BMP signaling pathway 21976273 Process
12168 GO:0030509 IMP acts_upstream_of_or_within BMP signaling pathway 17472960 Process
12168 GO:0030509 IMP involved_in BMP signaling pathway 18552156,26774823 Process
12168 GO:0045778 IMP involved_in positive regulation of ossification 12441304 Process
12168 GO:0045906 IMP involved_in negative regulation of vasoconstriction 18552156 Process
12168 GO:0045944 IMP involved_in positive regulation of transcription by RNA polymerase II 12441304 Process
12168 GO:0048286 IMP involved_in lung alveolus development 18552156 Process
12168 GO:0048738 IMP NOT involved_in cardiac muscle tissue development 19409885 Process
12168 GO:0048842 IMP involved_in positive regulation of axon extension involved in axon guidance 24052814 Process
12168 GO:0051148 IDA involved_in negative regulation of muscle cell differentiation 21976273 Process
12168 GO:0060173 IGI acts_upstream_of_or_within limb development 23610558 Process
12168 GO:0060412 IMP involved_in ventricular septum morphogenesis 12441304,19409885 Process
12168 GO:0060413 IMP involved_in atrial septum morphogenesis 19409885 Process
12168 GO:0060836 IMP involved_in lymphatic endothelial cell differentiation 19903896 Process
12168 GO:0060840 IMP involved_in artery development 19903896 Process
12168 GO:0060841 IMP involved_in venous blood vessel development 19903896 Process
12168 GO:0061298 IMP involved_in retina vasculature development in camera-type eye 19903896 Process
12168 GO:0061626 IMP NOT involved_in pharyngeal arch artery morphogenesis 19409885 Process
12168 GO:0061626 IMP involved_in pharyngeal arch artery morphogenesis 12441304 Process
12168 GO:1905314 IMP involved_in semi-lunar valve development 12441304,19409885 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
12168 GO:0004674 IDA enables protein serine/threonine kinase activity 21976273 Function
12168 GO:0004674 IMP enables protein serine/threonine kinase activity 11714695 Function
12168 GO:0005515 IPI enables protein binding 16923969,19424179 Function
12168 GO:0036122 IDA enables BMP binding 21976273 Function
12168 GO:0098821 IDA enables BMP receptor activity 21976273 Function
12168 GO:0098821 IMP enables BMP receptor activity 26774823 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
12168 GO:0005886 IDA is_active_in plasma membrane 21976273,23041979 Component
12168 GO:0005886 IDA located_in plasma membrane 23676498 Component
12168 GO:0005905 IDA is_active_in clathrin-coated pit 16923969 Component
12168 GO:0009986 IDA located_in cell surface 12117821 Component
12168 GO:0014069 IDA located_in postsynaptic density 17114649 Component
12168 GO:0030424 IDA is_active_in axon 17634368 Component
12168 GO:0030425 IDA is_active_in dendrite 17634368 Component
12168 GO:0044297 IDA is_active_in cell body 17634368 Component