Gene Ontology

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 12362
  • Symbol: Casp1
  • Description: caspase 1

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
12362 GO:0001666 IMP acts_upstream_of_or_within response to hypoxia 14663141 Process
12362 GO:0001819 IDA involved_in positive regulation of cytokine production 21147462 Process
12362 GO:0002221 IDA involved_in pattern recognition receptor signaling pathway 18725521 Process
12362 GO:0009617 IMP acts_upstream_of_or_within response to bacterium 24581500 Process
12362 GO:0010506 IMP acts_upstream_of_or_within regulation of autophagy 24581500 Process
12362 GO:0010934 IMP acts_upstream_of macrophage cytokine production 18490713 Process
12362 GO:0016485 IDA acts_upstream_of_or_within protein processing 11016935,15190255 Process
12362 GO:0016485 IMP acts_upstream_of_or_within protein processing 14663141,16301672 Process
12362 GO:0016540 IDA involved_in protein autoprocessing 21147462 Process
12362 GO:0032496 IDA acts_upstream_of_or_within response to lipopolysaccharide 16301672 Process
12362 GO:0032610 IMP acts_upstream_of interleukin-1 alpha production 18490713 Process
12362 GO:0032611 IGI acts_upstream_of_or_within interleukin-1 beta production 19158679 Process
12362 GO:0032611 IMP acts_upstream_of interleukin-1 beta production 18490713 Process
12362 GO:0032730 IMP acts_upstream_of_or_within positive regulation of interleukin-1 alpha production 18490713 Process
12362 GO:0032731 IDA involved_in positive regulation of interleukin-1 beta production 18725521,21147462,27270401,29255148 Process
12362 GO:0032731 IMP acts_upstream_of_or_within positive regulation of interleukin-1 beta production 18490713 Process
12362 GO:0033198 IMP acts_upstream_of_or_within response to ATP 18490713 Process
12362 GO:0042742 IDA involved_in defense response to bacterium 35705808 Process
12362 GO:0043123 IDA involved_in positive regulation of I-kappaB kinase/NF-kappaB signaling 16585594 Process
12362 GO:0043525 IDA involved_in positive regulation of neuron apoptotic process 14663141 Process
12362 GO:0050727 IMP acts_upstream_of_or_within regulation of inflammatory response 22297845 Process
12362 GO:0050729 IDA involved_in positive regulation of inflammatory response 18725521,27270401,32109412 Process
12362 GO:0050829 IMP involved_in defense response to Gram-negative bacterium 29887864 Process
12362 GO:0051604 IDA involved_in protein maturation 32109412,35705808 Process
12362 GO:0051882 IMP acts_upstream_of_or_within mitochondrial depolarization 23028046 Process
12362 GO:0060081 IMP acts_upstream_of_or_within membrane hyperpolarization 23028046 Process
12362 GO:0060907 IMP acts_upstream_of_or_within positive regulation of macrophage cytokine production 18490713 Process
12362 GO:0070269 IDA involved_in pyroptosis 21147462,26611636 Process
12362 GO:0070269 IMP acts_upstream_of_or_within pyroptosis 22002608 Process
12362 GO:0090200 IDA involved_in positive regulation of release of cytochrome c from mitochondria 14663141 Process
12362 GO:0097300 IDA acts_upstream_of_or_within programmed necrotic cell death 16429160 Process
12362 GO:0140970 IDA involved_in AIM2 inflammasome complex assembly 23567559,27846608,32350463 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
12362 GO:0004197 IDA enables cysteine-type endopeptidase activity 18667412,21147462,23395675,32109412,35705808 Function
12362 GO:0005515 IPI enables protein binding 8670890,10051653,11684016,15190255,22801494,22885697,25605870,..... Function
12362 GO:0008233 IDA enables peptidase activity 18490713 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
12362 GO:0005576 IDA located_in extracellular region 15190255 Component
12362 GO:0005737 IDA is_active_in cytoplasm 21147462 Component
12362 GO:0005829 IDA is_active_in cytosol 35705808 Component
12362 GO:0072557 IDA part_of IPAF inflammasome complex 21874021 Component