Gene Ontology

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 12540
  • Symbol: Cdc42
  • Description: cell division cycle 42

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
12540 GO:0000322 IDA located_in storage vacuole 21828338 Component
12540 GO:0005737 IDA located_in cytoplasm 15775979,19796622 Component
12540 GO:0005829 IDA located_in cytosol 21828338 Component
12540 GO:0005886 IDA located_in plasma membrane 21828338,25217619 Component
12540 GO:0005911 IDA located_in cell-cell junction 23793062 Component
12540 GO:0031252 IDA is_active_in cell leading edge 31219639 Component
12540 GO:0031256 IDA located_in leading edge membrane 22461490 Component
12540 GO:0042995 IDA located_in cell projection 15728722 Component
12540 GO:0043209 HDA located_in myelin sheath 17634366 Component
12540 GO:0045177 IDA located_in apical part of cell 16892058 Component
12540 GO:0045335 IDA located_in phagocytic vesicle 19144319 Component
12540 GO:0071944 IDA located_in cell periphery 19796622 Component
12540 GO:0098978 IDA is_active_in glutamatergic synapse 25851601 Component
12540 GO:0098978 IMP is_active_in glutamatergic synapse 25851601 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
12540 GO:0003161 IGI acts_upstream_of_or_within cardiac conduction system development 21690310 Process
12540 GO:0003253 IMP involved_in cardiac neural crest cell migration involved in outflow tract morphogenesis 31219639 Process
12540 GO:0006468 IMP involved_in protein phosphorylation 31219639 Process
12540 GO:0006897 IMP acts_upstream_of_or_within endocytosis 24792215 Process
12540 GO:0007088 IMP acts_upstream_of_or_within regulation of mitotic nuclear division 16892058 Process
12540 GO:0007097 IMP acts_upstream_of_or_within nuclear migration 15882626,16892058 Process
12540 GO:0008104 IMP acts_upstream_of_or_within protein localization 16621792 Process
12540 GO:0034332 IMP acts_upstream_of_or_within adherens junction organization 16892058 Process
12540 GO:0035050 IMP involved_in embryonic heart tube development 31219639 Process
12540 GO:0035088 IMP acts_upstream_of_or_within establishment or maintenance of apical/basal cell polarity 16892058 Process
12540 GO:0036336 IGI acts_upstream_of_or_within dendritic cell migration 22461490 Process
12540 GO:0043393 IDA acts_upstream_of_or_within regulation of protein binding 19244314 Process
12540 GO:0043410 IDA acts_upstream_of_or_within positive regulation of MAPK cascade 19244314 Process
12540 GO:0043552 IMP acts_upstream_of_or_within positive regulation of phosphatidylinositol 3-kinase activity 15728722 Process
12540 GO:0046847 IDA acts_upstream_of_or_within filopodium assembly 10699171 Process
12540 GO:0048549 IMP involved_in positive regulation of pinocytosis 24792215 Process
12540 GO:0048664 IMP acts_upstream_of_or_within neuron fate determination 16892058 Process
12540 GO:0051491 IMP involved_in positive regulation of filopodium assembly 22494997 Process
12540 GO:0051647 IMP acts_upstream_of_or_within nucleus localization 16892058 Process
12540 GO:0051649 IMP acts_upstream_of_or_within establishment of localization in cell 24792215 Process
12540 GO:0060047 IGI acts_upstream_of_or_within heart contraction 21690310 Process
12540 GO:0060501 IMP involved_in positive regulation of epithelial cell proliferation involved in lung morphogenesis 23219958 Process
12540 GO:0060997 IMP involved_in dendritic spine morphogenesis 25851601 Process
12540 GO:0071346 IDA acts_upstream_of_or_within cellular response to type II interferon 19144319 Process
12540 GO:0086101 IMP involved_in endothelin receptor signaling pathway involved in heart process 31219639 Process
12540 GO:0099175 IDA involved_in regulation of postsynapse organization 25851601 Process
12540 GO:0099175 IMP involved_in regulation of postsynapse organization 25851601 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
12540 GO:0003924 IDA enables GTPase activity 10699171,15249579,18838382 Function
12540 GO:0003924 IGI enables GTPase activity 18838382 Function
12540 GO:0005515 IPI enables protein binding 8464478,10490598,10954424,11035016,12123608,12773384,15537656,..... Function
12540 GO:0019901 IPI enables protein kinase binding 21048939 Function
12540 GO:0030742 IPI enables GTP-dependent protein binding 10954424 Function