Gene Ontology

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 13039
  • Symbol: Ctsl
  • Description: cathepsin L

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
13039 GO:0004175 IMP enables endopeptidase activity 18450756,28835281 Function
13039 GO:0005515 IPI enables protein binding 11483509,12417635,14681235 Function
13039 GO:0016807 IDA enables cysteine-type carboxypeptidase activity 11023992 Function
13039 GO:0042393 IDA enables histone binding 18957203 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
13039 GO:0005615 IDA located_in extracellular space 9310336,10716919,12417635,12782676 Component
13039 GO:0005634 IDA located_in nucleus 18957203 Component
13039 GO:0005730 IDA located_in nucleolus 20338168 Component
13039 GO:0005764 IDA located_in lysosome 11023992,11483509,12782676,15099520 Component
13039 GO:0009897 IDA located_in external side of plasma membrane 12782676 Component
13039 GO:0031410 IDA located_in cytoplasmic vesicle 9310336 Component
13039 GO:0062023 HDA located_in collagen-containing extracellular matrix 28071719 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
13039 GO:0006508 IDA involved_in proteolysis 18957203 Process
13039 GO:0006590 IMP involved_in thyroid hormone generation 12782676 Process
13039 GO:0010839 IMP acts_upstream_of_or_within negative regulation of keratinocyte proliferation 11023992 Process
13039 GO:0030574 IDA involved_in collagen catabolic process 10716919 Process
13039 GO:0031069 IMP acts_upstream_of_or_within hair follicle morphogenesis 11023992 Process
13039 GO:0042637 IMP acts_upstream_of_or_within catagen 11023992 Process
13039 GO:0043373 IMP involved_in CD4-positive, alpha-beta T cell lineage commitment 9545226 Process
13039 GO:0043616 IMP acts_upstream_of keratinocyte proliferation 11023992 Process
13039 GO:0046697 IGI acts_upstream_of_or_within decidualization 9310336 Process
13039 GO:0048002 IMP involved_in antigen processing and presentation of peptide antigen 9545226,12021314 Process
13039 GO:0051603 IMP involved_in proteolysis involved in protein catabolic process 12782676 Process
13039 GO:0060309 IMP involved_in elastin catabolic process 12417635 Process
13039 GO:0060441 IMP NOT involved_in epithelial tube branching involved in lung morphogenesis 17500053 Process