Gene Ontology

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 13548
  • Symbol: Dyrk1a
  • Description: dual-specificity tyrosine phosphorylation regulated kinase 1a

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
13548 GO:0004674 IDA enables protein serine/threonine kinase activity 20123978,20736167 Function
13548 GO:0004674 IGI enables protein serine/threonine kinase activity 17906291 Function
13548 GO:0005515 IPI enables protein binding 15199138,20123978,20167603,20736167,21470964,21965663..... Function
13548 GO:0042802 IPI enables identical protein binding 9070862,21965663 Function
13548 GO:0043621 IPI enables protein self-association 9070862 Function
13548 GO:0048156 IPI enables tau protein binding 17906291,20736167 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
13548 GO:0005634 IDA located_in nucleus 9070862,21878370 Component
13548 GO:0005737 IDA located_in cytoplasm 21878370 Component
13548 GO:0005856 IDA located_in cytoskeleton 24327345 Component
13548 GO:0030424 IDA located_in axon 21878370 Component
13548 GO:0030425 IDA located_in dendrite 21878370 Component
13548 GO:1990904 IDA part_of ribonucleoprotein complex 21709260 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
13548 GO:0007623 IMP involved_in circadian rhythm 20123978 Process
13548 GO:0018105 IDA involved_in peptidyl-serine phosphorylation 20123978 Process
13548 GO:0018107 IDA involved_in peptidyl-threonine phosphorylation 20736167 Process
13548 GO:0018108 IDA acts_upstream_of_or_within peptidyl-tyrosine phosphorylation 21470964 Process
13548 GO:0031115 IDA involved_in negative regulation of microtubule polymerization 17906291 Process
13548 GO:0038083 IDA involved_in peptidyl-tyrosine autophosphorylation 24327345 Process
13548 GO:0043518 IDA involved_in negative regulation of DNA damage response, signal transduction by p53 class mediator 20736167 Process
13548 GO:0048025 IMP acts_upstream_of_or_within negative regulation of mRNA splicing, via spliceosome 21470964 Process
13548 GO:0090312 IDA involved_in positive regulation of protein deacetylation 20736167 Process