Gene Ontology

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 13649
  • Symbol: Egfr
  • Description: epidermal growth factor receptor

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
13649 GO:0000902 IGI acts_upstream_of_or_within cell morphogenesis 17686994 Process
13649 GO:0001892 IMP acts_upstream_of_or_within embryonic placenta development 7618084 Process
13649 GO:0001942 IGI acts_upstream_of_or_within hair follicle development 9030684 Process
13649 GO:0001942 IMP acts_upstream_of_or_within hair follicle development 7618084 Process
13649 GO:0007165 IDA acts_upstream_of_or_within signal transduction 11940581 Process
13649 GO:0007173 IDA acts_upstream_of_or_within epidermal growth factor receptor signaling pathway 14712229,15695332 Process
13649 GO:0007173 IDA involved_in epidermal growth factor receptor signaling pathway 6248866,7678348,7752576,8456283,8702723,9556621,12761849..... Process
13649 GO:0007173 IGI acts_upstream_of_or_within epidermal growth factor receptor signaling pathway 7641815 Process
13649 GO:0007173 IGI involved_in epidermal growth factor receptor signaling pathway 28783046 Process
13649 GO:0007173 IMP acts_upstream_of_or_within epidermal growth factor receptor signaling pathway 17686994 Process
13649 GO:0007173 IMP involved_in epidermal growth factor receptor signaling pathway 12399441,23333074,23899604,30770250 Process
13649 GO:0007435 IMP acts_upstream_of_or_within salivary gland morphogenesis 10521784 Process
13649 GO:0008283 IGI acts_upstream_of cell population proliferation 18656477 Process
13649 GO:0008284 IDA acts_upstream_of_or_within positive regulation of cell population proliferation 14712229 Process
13649 GO:0008284 IGI acts_upstream_of_or_within positive regulation of cell population proliferation 7641815,18656477 Process
13649 GO:0008544 IMP acts_upstream_of_or_within epidermis development 7618084 Process
13649 GO:0021795 IMP acts_upstream_of_or_within cerebral cortex cell migration 7618084 Process
13649 GO:0038134 IDA involved_in ERBB2-EGFR signaling pathway 8702723,9556621,21897861,21946538 Process
13649 GO:0038134 IMP involved_in ERBB2-EGFR signaling pathway 18701712 Process
13649 GO:0042059 IDA involved_in negative regulation of epidermal growth factor receptor signaling pathway 23457600 Process
13649 GO:0042059 IMP involved_in negative regulation of epidermal growth factor receptor signaling pathway 11823423 Process
13649 GO:0042127 IGI acts_upstream_of_or_within regulation of cell population proliferation 11818567 Process
13649 GO:0046777 IDA acts_upstream_of_or_within protein autophosphorylation 15314156 Process
13649 GO:0048146 IMP involved_in positive regulation of fibroblast proliferation 20208556 Process
13649 GO:0048546 IMP acts_upstream_of_or_within digestive tract morphogenesis 7618084 Process
13649 GO:0050673 IMP acts_upstream_of epithelial cell proliferation 7618084 Process
13649 GO:0050679 IMP acts_upstream_of_or_within positive regulation of epithelial cell proliferation 7618084 Process
13649 GO:0050730 IMP acts_upstream_of_or_within regulation of peptidyl-tyrosine phosphorylation 11940581 Process
13649 GO:0060571 IMP acts_upstream_of_or_within morphogenesis of an epithelial fold 7618084 Process
13649 GO:0061029 IGI acts_upstream_of_or_within eyelid development in camera-type eye 9030684 Process
13649 GO:0071230 IDA involved_in cellular response to amino acid stimulus 22711986 Process
13649 GO:0071363 IDA acts_upstream_of_or_within cellular response to growth factor stimulus 8702723 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
13649 GO:0004713 IDA enables protein tyrosine kinase activity 15383614,15962011,23457600 Function
13649 GO:0004713 IMP enables protein tyrosine kinase activity 11823423,15383614 Function
13649 GO:0004714 IDA enables transmembrane receptor protein tyrosine kinase activity 7752576,8456283,8702723,9556621,21897861 Function
13649 GO:0004714 IGI enables transmembrane receptor protein tyrosine kinase activity 28783046 Function
13649 GO:0004714 IMP enables transmembrane receptor protein tyrosine kinase activity 12399441,23333074,23899604,30770250 Function
13649 GO:0005006 IDA enables epidermal growth factor receptor activity 6248866,7752576,9529375,11823423,11940581,14712229,21946538,23..... Function
13649 GO:0005006 IGI enables epidermal growth factor receptor activity 16357442 Function
13649 GO:0005006 IMP enables epidermal growth factor receptor activity 18701712 Function
13649 GO:0005515 IPI enables protein binding 11274221,12919676,15467833,15695332,15728722,16120644,16954185..... Function
13649 GO:0016301 IDA enables kinase activity 12808090 Function
13649 GO:0030297 IDA enables transmembrane receptor protein tyrosine kinase activator activity 7678348 Function
13649 GO:0048408 IDA enables epidermal growth factor binding 7678348 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
13649 GO:0005622 IDA located_in intracellular anatomical structure 10534613 Component
13649 GO:0005634 IDA located_in nucleus 20208556 Component
13649 GO:0005886 IDA is_active_in plasma membrane 6248866,7678348,7752576,8456283,8621573,8702723,9556621,153836..... Component
13649 GO:0005886 IDA located_in plasma membrane 7641815 Component
13649 GO:0005886 IGI is_active_in plasma membrane 28783046 Component
13649 GO:0009986 IDA located_in cell surface 23918928 Component
13649 GO:0016323 IDA located_in basolateral plasma membrane 7723235 Component
13649 GO:0030139 IDA located_in endocytic vesicle 10534613 Component
13649 GO:0048471 IDA located_in perinuclear region of cytoplasm 20208556 Component