Gene Ontology

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 13860
  • Symbol: Eps8
  • Description: epidermal growth factor receptor pathway substrate 8

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
13860 GO:0003779 IDA enables actin binding 11524436,15558031,20532239 Function
13860 GO:0005515 IPI enables protein binding 9010225,11524436,15289329,15558031,17018287,17115031,19208628,..... Function
13860 GO:0031267 IDA enables small GTPase binding 11524436 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
13860 GO:0005903 IDA located_in brush border 22114352 Component
13860 GO:0005938 IDA located_in cell cortex 11524436,23314863 Component
13860 GO:0014069 IDA located_in postsynaptic density 17018287 Component
13860 GO:0017146 IDA part_of NMDA selective glutamate receptor complex 17018287 Component
13860 GO:0032420 IDA located_in stereocilium 21236676,24741995 Component
13860 GO:0032421 IDA located_in stereocilium bundle 23918390 Component
13860 GO:0032426 IDA located_in stereocilium tip 23918390 Component
13860 GO:0032587 IDA located_in ruffle membrane 11524436 Component
13860 GO:0045202 IDA located_in synapse 17018287 Component
13860 GO:0098978 EXP is_active_in glutamatergic synapse 27450093 Component
13860 GO:0098978 IDA is_active_in glutamatergic synapse 27450093 Component
13860 GO:0098978 IEP is_active_in glutamatergic synapse 27450093 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
13860 GO:0008344 IMP acts_upstream_of_or_within adult locomotory behavior 17018287 Process
13860 GO:0008360 IMP involved_in regulation of cell shape 17115031,23314863 Process
13860 GO:0010458 IMP involved_in exit from mitosis 23314863 Process
13860 GO:0016601 IDA involved_in Rac protein signal transduction 11524436 Process
13860 GO:0030036 IMP acts_upstream_of_or_within actin cytoskeleton organization 17018287 Process
13860 GO:0030832 IMP involved_in regulation of actin filament length 21236676 Process
13860 GO:0036336 IMP involved_in dendritic cell migration 21835647 Process
13860 GO:0048149 IMP acts_upstream_of_or_within behavioral response to ethanol 17018287 Process
13860 GO:0051016 IDA involved_in barbed-end actin filament capping 15558031,20532239 Process
13860 GO:0051016 IMP involved_in barbed-end actin filament capping 23314863 Process
13860 GO:0051017 IDA involved_in actin filament bundle assembly 20532239 Process
13860 GO:0051017 IGI acts_upstream_of_or_within actin filament bundle assembly 19208628 Process
13860 GO:0051017 IMP involved_in actin filament bundle assembly 17115031 Process
13860 GO:0051764 IDA involved_in actin crosslink formation 20532239 Process
13860 GO:0051764 IMP involved_in actin crosslink formation 17115031 Process
13860 GO:0070358 IDA involved_in actin polymerization-dependent cell motility 15558031 Process
13860 GO:0099072 EXP involved_in regulation of postsynaptic membrane neurotransmitter receptor levels 27450093 Process
13860 GO:0099072 IDA involved_in regulation of postsynaptic membrane neurotransmitter receptor levels 27450093 Process
13860 GO:0099072 IEP involved_in regulation of postsynaptic membrane neurotransmitter receptor levels 27450093 Process
13860 GO:1990830 IEP acts_upstream_of_or_within cellular response to leukemia inhibitory factor 20439489 Process