Gene Ontology

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 13866
  • Symbol: Erbb2
  • Description: erb-b2 receptor tyrosine kinase 2

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
13866 GO:0001934 IMP involved_in positive regulation of protein phosphorylation 22019888 Process
13866 GO:0007399 IMP acts_upstream_of_or_within nervous system development 15496447 Process
13866 GO:0007422 IMP acts_upstream_of_or_within peripheral nervous system development 9362461 Process
13866 GO:0007507 IMP acts_upstream_of_or_within heart development 9362461,12072561 Process
13866 GO:0007528 IMP acts_upstream_of_or_within neuromuscular junction development 10655525 Process
13866 GO:0008045 IMP acts_upstream_of_or_within motor neuron axon guidance 10655525 Process
13866 GO:0010628 IMP acts_upstream_of_or_within positive regulation of gene expression 24364879 Process
13866 GO:0033080 IMP acts_upstream_of immature T cell proliferation in thymus 16230479 Process
13866 GO:0033088 IMP acts_upstream_of_or_within negative regulation of immature T cell proliferation in thymus 16230479 Process
13866 GO:0038133 IDA involved_in ERBB2-ERBB3 signaling pathway 8702723,9742126 Process
13866 GO:0038134 IDA involved_in ERBB2-EGFR signaling pathway 8702723,9556621,18701712,21897861 Process
13866 GO:0038134 IGI involved_in ERBB2-EGFR signaling pathway 16357442 Process
13866 GO:0038135 IDA involved_in ERBB2-ERBB4 signaling pathway 9556621 Process
13866 GO:0038135 IGI involved_in ERBB2-ERBB4 signaling pathway 12621152 Process
13866 GO:0042552 IMP acts_upstream_of_or_within myelination 10704452 Process
13866 GO:0043547 IMP involved_in positive regulation of GTPase activity 22019888 Process
13866 GO:0048709 IMP acts_upstream_of_or_within oligodendrocyte differentiation 19139271 Process
13866 GO:0099645 IDA involved_in neurotransmitter receptor localization to postsynaptic specialization membrane 22184199 Process
13866 GO:0099645 IMP involved_in neurotransmitter receptor localization to postsynaptic specialization membrane 22184199 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
13866 GO:0004713 IDA enables protein tyrosine kinase activity 8702723,9556621,9742126,18701712,21897861 Function
13866 GO:0004713 IGI enables protein tyrosine kinase activity 12621152,16357442 Function
13866 GO:0005515 IPI enables protein binding 10878805,11276227,17043217,20639901,20876300,23553667,23897819..... Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
13866 GO:0005737 IDA located_in cytoplasm 15306553 Component
13866 GO:0005886 IDA is_active_in plasma membrane 8702723,9556621,9742126,12621152,19029950,21897861 Component
13866 GO:0005886 IDA located_in plasma membrane 23553667 Component
13866 GO:0016324 IDA located_in apical plasma membrane 15306553 Component
13866 GO:0031410 IDA located_in cytoplasmic vesicle 23553667 Component
13866 GO:0031594 IDA is_active_in neuromuscular junction 22184199 Component
13866 GO:0031594 IMP is_active_in neuromuscular junction 22184199 Component
13866 GO:0042734 IDA is_active_in presynaptic membrane 24803543 Component
13866 GO:0043209 IDA located_in myelin sheath 15044753 Component