Gene Ontology

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 13869
  • Symbol: Erbb4
  • Description: erb-b2 receptor tyrosine kinase 4

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
13869 GO:0001755 IMP involved_in neural crest cell migration 10655590 Process
13869 GO:0007166 IDA involved_in cell surface receptor signaling pathway 24218551 Process
13869 GO:0007399 IMP acts_upstream_of_or_within nervous system development 7477376 Process
13869 GO:0007416 IDA involved_in synapse assembly 20393464 Process
13869 GO:0007416 IMP involved_in synapse assembly 20393464 Process
13869 GO:0007507 IMP acts_upstream_of_or_within heart development 7477376 Process
13869 GO:0007595 IMP involved_in lactation 10508857 Process
13869 GO:0009880 IMP involved_in embryonic pattern specification 10655590 Process
13869 GO:0014068 IGI acts_upstream_of_or_within positive regulation of phosphatidylinositol 3-kinase signaling 18458158 Process
13869 GO:0021551 IMP involved_in central nervous system morphogenesis 10655590 Process
13869 GO:0021889 IMP involved_in olfactory bulb interneuron differentiation 15543145 Process
13869 GO:0030334 IMP involved_in regulation of cell migration 15543145 Process
13869 GO:0038130 IMP involved_in ERBB4 signaling pathway 16446434,28822966 Process
13869 GO:0038135 IDA involved_in ERBB2-ERBB4 signaling pathway 8702723,9556621 Process
13869 GO:0038135 IGI involved_in ERBB2-ERBB4 signaling pathway 12621152 Process
13869 GO:0038138 IDA involved_in ERBB4-ERBB4 signaling pathway 8702723,9168114,9168115,9556621,23033483,28822966 Process
13869 GO:0042531 IMP involved_in positive regulation of tyrosine phosphorylation of STAT protein 10508857,16837552 Process
13869 GO:0045165 IDA acts_upstream_of_or_within cell fate commitment 12399441 Process
13869 GO:0045893 IMP involved_in positive regulation of DNA-templated transcription 16837552 Process
13869 GO:0046427 IMP involved_in positive regulation of receptor signaling pathway via JAK-STAT 16837552 Process
13869 GO:0060045 IMP involved_in positive regulation of cardiac muscle cell proliferation 19632177 Process
13869 GO:0060644 IMP involved_in mammary gland epithelial cell differentiation 16837552 Process
13869 GO:0060749 IMP involved_in mammary gland alveolus development 10508857 Process
13869 GO:0061026 IMP involved_in cardiac muscle tissue regeneration 19632177 Process
13869 GO:0071364 IDA acts_upstream_of_or_within cellular response to epidermal growth factor stimulus 8702723 Process
13869 GO:0072046 IMP acts_upstream_of_or_within establishment of planar polarity involved in nephron morphogenesis 22076439 Process
13869 GO:0099645 IDA involved_in neurotransmitter receptor localization to postsynaptic specialization membrane 22184199 Process
13869 GO:0099645 IMP involved_in neurotransmitter receptor localization to postsynaptic specialization membrane 22184199 Process
13869 GO:2000010 IGI acts_upstream_of_or_within positive regulation of protein localization to cell surface 18458158 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
13869 GO:0004714 IDA enables transmembrane receptor protein tyrosine kinase activity 9168114,9556621 Function
13869 GO:0005006 IGI enables epidermal growth factor receptor activity 12621152 Function
13869 GO:0005515 IPI enables protein binding 16061658 Function
13869 GO:0038131 IDA enables neuregulin receptor activity 8702723,9168115,23033483,28822966 Function
13869 GO:0038131 IMP enables neuregulin receptor activity 19632177 Function
13869 GO:0050811 IDA enables GABA receptor binding 24218551 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
13869 GO:0005886 IDA is_active_in plasma membrane 8702723,9168114,9168115,9556621,12621152,19793984,23033483,242..... Component
13869 GO:0031594 IDA is_active_in neuromuscular junction 22184199 Component
13869 GO:0031594 IMP is_active_in neuromuscular junction 22184199 Component
13869 GO:0042734 IDA is_active_in presynaptic membrane 20393464,24803543 Component
13869 GO:0098839 IDA is_active_in postsynaptic density membrane 20393464,24218551 Component
13869 GO:0098978 IDA is_active_in glutamatergic synapse 20393464 Component
13869 GO:0098982 IDA is_active_in GABA-ergic synapse 20393464 Component
13869 GO:0098982 IMP is_active_in GABA-ergic synapse 20393464 Component