Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 1387
  • Symbol: CREBBP
  • Description: CREB binding lysine acetyltransferase

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
1387 GO:0000122 IDA involved_in negative regulation of transcription by RNA polymerase II 21539536 Process
1387 GO:0006473 IDA involved_in protein acetylation 15273251,24207024,24939902,28790157 Process
1387 GO:0016479 IDA involved_in negative regulation of transcription by RNA polymerase I 30540930 Process
1387 GO:0018076 IDA involved_in N-terminal peptidyl-lysine acetylation 12435739,35675826 Process
1387 GO:0030511 IMP involved_in positive regulation of transforming growth factor beta receptor signaling pathway 25514493 Process
1387 GO:0031648 IMP involved_in protein destabilization 24939902 Process
1387 GO:0031669 IDA involved_in cellular response to nutrient levels 35675826 Process
1387 GO:0034644 IDA involved_in cellular response to UV 24939902 Process
1387 GO:0038061 IDA involved_in NIK/NF-kappaB signaling 11742995 Process
1387 GO:0045893 IDA involved_in positive regulation of DNA-templated transcription 11742995 Process
1387 GO:0045944 IDA involved_in positive regulation of transcription by RNA polymerase II 12169688 Process
1387 GO:1900182 IDA involved_in positive regulation of protein localization to nucleus 35675826 Process

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
1387 GO:0000785 IDA part_of chromatin 21539536 Component
1387 GO:0005634 IDA located_in nucleus 12929931,25593309 Component
1387 GO:0005654 IDA located_in nucleoplasm Component
1387 GO:0005737 IDA is_active_in cytoplasm 35675826 Component
1387 GO:0005737 IDA located_in cytoplasm 12929931 Component
1387 GO:0016604 IDA located_in nuclear body 15488321 Component

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
1387 GO:0001223 IPI enables transcription coactivator binding 11349124 Function
1387 GO:0002039 IPI enables p53 binding 9194565 Function
1387 GO:0003682 IDA enables chromatin binding 24939902 Function
1387 GO:0003684 IDA enables damaged DNA binding 24939902 Function
1387 GO:0003713 IDA enables transcription coactivator activity 12169688,12435739,12586840,12929931,14645221 Function
1387 GO:0003713 IPI enables transcription coactivator activity 8684459 Function
1387 GO:0003714 IDA enables transcription corepressor activity 21539536 Function
1387 GO:0004402 IDA enables histone acetyltransferase activity 11742995 Function
1387 GO:0005515 IPI enables protein binding 8684459,9018065,9194564,9323138,9687513,9811832,9887100,100498..... Function
1387 GO:0016407 EXP enables acetyltransferase activity 12456660,16135789 Function
1387 GO:0016407 IDA enables acetyltransferase activity 11742995,15273251,24939902 Function
1387 GO:0043426 IDA enables MRF binding 8621548 Function
1387 GO:0061629 IPI enables RNA polymerase II-specific DNA-binding transcription factor binding 16043483,21539536 Function
1387 GO:0061733 EXP enables peptide-lysine-N-acetyltransferase activity 34239064 Function
1387 GO:0061733 IDA enables peptide-lysine-N-acetyltransferase activity 24207024,28790157,30540930,35675826 Function
1387 GO:0140297 IPI enables DNA-binding transcription factor binding 15509593,15674325 Function