Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 1410
  • Symbol: CRYAB
  • Description: crystallin alpha B

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
1410 GO:0001540 IPI enables amyloid-beta binding 23106396 Function
1410 GO:0005198 IDA enables structural molecule activity 16303126 Function
1410 GO:0005515 IPI enables protein binding 11700327,12235146,12601044,14752512,16049941,17046756,18330356..... Function
1410 GO:0042802 IPI enables identical protein binding 12601044,16303126,18330356,19651604,20802487,21464278,22143763..... Function
1410 GO:0042803 IPI enables protein homodimerization activity 19646995 Function
1410 GO:0044877 IPI enables protein-containing complex binding 23106396 Function
1410 GO:0051082 IPI enables unfolded protein binding 16303126 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
1410 GO:0005634 IDA located_in nucleus 19464326,20587334 Component
1410 GO:0005737 IDA located_in cytoplasm 14752512,19464326,20587334 Component
1410 GO:0032991 IDA part_of protein-containing complex 16303126,20587334 Component
1410 GO:0070062 HDA located_in extracellular exosome 19056867,23533145 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
1410 GO:0031333 IDA involved_in negative regulation of protein-containing complex assembly 23106396 Process
1410 GO:0032387 IDA involved_in negative regulation of intracellular transport 14752512 Process
1410 GO:0043066 IDA involved_in negative regulation of apoptotic process 14752512 Process
1410 GO:0043067 IMP acts_upstream_of_or_within regulation of programmed cell death 23542032 Process
1410 GO:0045892 IDA involved_in negative regulation of DNA-templated transcription 20587334 Process
1410 GO:0050821 IMP involved_in protein stabilization 12235146 Process
1410 GO:0071480 IMP acts_upstream_of_or_within cellular response to gamma radiation 23542032 Process
1410 GO:1905907 IDA involved_in negative regulation of amyloid fibril formation 23106396 Process