Gene Ontology

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 1509
• Symbol: CTSD
• Description: cathepsin D

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
1509	GO:0005515	IPI	enables	protein binding	17112520,28493053,32814053	Function
1509	GO:0008233	IDA	enables	peptidase activity	16997486	Function
1509	GO:0008233	IMP	enables	peptidase activity	17188016	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
1509	GO:0005576	HDA	located_in	extracellular region	27068509	Component
1509	GO:0005615	HDA	located_in	extracellular space	16502470,20551380	Component
1509	GO:0005764	IDA	located_in	lysosome	1692625,1837142,2350688,19723497	Component
1509	GO:0005765	IDA	located_in	lysosomal membrane	17188016	Component
1509	GO:0010008	IDA	located_in	endosome membrane	17188016	Component
1509	GO:0045121	IDA	located_in	membrane raft	25204797	Component
1509	GO:0062023	HDA	colocalizes_with	collagen-containing extracellular matrix	20551380	Component
1509	GO:0062023	HDA	located_in	collagen-containing extracellular matrix	25037231,28344315,28675934	Component
1509	GO:0070062	HDA	located_in	extracellular exosome	19056867,23533145	Component

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
1509	GO:0006508	IDA	involved_in	proteolysis	16997486	Process
1509	GO:0006508	IMP	involved_in	proteolysis	17188016	Process
1509	GO:0042159	IDA	involved_in	lipoprotein catabolic process	16997486	Process
1509	GO:0043065	IDA	involved_in	positive regulation of apoptotic process	12107093	Process
1509	GO:0043280	IDA	involved_in	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	12107093	Process
1509	GO:0070201	IDA	involved_in	regulation of establishment of protein localization	12107093	Process