Gene Ontology

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 15185
  • Symbol: Hdac6
  • Description: histone deacetylase 6

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
15185 GO:0000209 IDA acts_upstream_of_or_within protein polyubiquitination 11689694 Process
15185 GO:0006476 IDA acts_upstream_of_or_within protein deacetylation 12486003 Process
15185 GO:0006511 IGI acts_upstream_of_or_within ubiquitin-dependent protein catabolic process 16810319 Process
15185 GO:0006511 IMP acts_upstream_of_or_within ubiquitin-dependent protein catabolic process 16810319 Process
15185 GO:0007026 IDA acts_upstream_of_or_within negative regulation of microtubule depolymerization 12486003 Process
15185 GO:0007519 IMP acts_upstream_of_or_within skeletal muscle tissue development Process
15185 GO:0014902 IMP acts_upstream_of_or_within myotube differentiation Process
15185 GO:0031648 IMP involved_in protein destabilization 24882211 Process
15185 GO:0032984 IGI acts_upstream_of_or_within protein-containing complex disassembly 17785525 Process
15185 GO:0033138 IMP involved_in positive regulation of peptidyl-serine phosphorylation 23962722 Process
15185 GO:0034983 IMP involved_in peptidyl-lysine deacetylation 23962722 Process
15185 GO:0043162 IMP acts_upstream_of_or_within ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway 17785525 Process
15185 GO:0045598 IMP acts_upstream_of_or_within regulation of fat cell differentiation 23126280 Process
15185 GO:0048668 IMP acts_upstream_of_or_within collateral sprouting 24113571 Process
15185 GO:0051646 IMP involved_in mitochondrion localization 20457763 Process
15185 GO:0060997 IMP acts_upstream_of_or_within dendritic spine morphogenesis 24113571 Process
15185 GO:0070201 IMP acts_upstream_of_or_within regulation of establishment of protein localization 22792322 Process
15185 GO:0070842 IGI acts_upstream_of_or_within aggresome assembly 16810319 Process
15185 GO:0070846 IMP acts_upstream_of_or_within Hsp90 deacetylation 17785525 Process
15185 GO:0071218 IMP acts_upstream_of_or_within cellular response to misfolded protein 17785525 Process
15185 GO:0090042 IDA involved_in tubulin deacetylation 19893491 Process
15185 GO:0090042 IMP acts_upstream_of_or_within tubulin deacetylation 12606581,16810319,17785525 Process
15185 GO:0098779 IGI involved_in positive regulation of mitophagy in response to mitochondrial depolarization 20457763 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
15185 GO:0004407 IDA enables histone deacetylase activity 9891014,11689694 Function
15185 GO:0004407 IMP enables histone deacetylase activity 24882211 Function
15185 GO:0005515 IPI enables protein binding 11689694,19893491,22193721,22792322,24113571,24955524,25873389..... Function
15185 GO:0008017 IDA enables microtubule binding 19893491 Function
15185 GO:0042903 IDA enables tubulin deacetylase activity 12606581,19893491 Function
15185 GO:0042903 IGI enables tubulin deacetylase activity 27430620 Function
15185 GO:0042903 IMP enables tubulin deacetylase activity 19457097 Function
15185 GO:0043014 IDA enables alpha-tubulin binding Function
15185 GO:0043130 IDA enables ubiquitin binding 11689694,16810319 Function
15185 GO:0048156 IPI enables tau protein binding 19457097 Function
15185 GO:0048487 IDA enables beta-tubulin binding 12606581 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
15185 GO:0005634 IDA located_in nucleus 19893491 Component
15185 GO:0005737 IDA located_in cytoplasm 11689694 Component
15185 GO:0005829 IDA located_in cytosol 19893491 Component
15185 GO:0015630 IDA located_in microtubule cytoskeleton 12606581 Component
15185 GO:0030424 IDA located_in axon 16933150 Component
15185 GO:0030425 IDA located_in dendrite 16933150 Component
15185 GO:0032991 IPI part_of protein-containing complex 17785525 Component
15185 GO:0043005 IDA located_in neuron projection 24113571 Component
15185 GO:0043025 IDA located_in neuronal cell body 24113571 Component
15185 GO:0043204 IDA located_in perikaryon 16933150 Component