Gene Ontology

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 15205
  • Symbol: Hes1
  • Description: hes family bHLH transcription factor 1

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
15205 GO:0000122 IDA acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II 11260262,15870295,16314515 Process
15205 GO:0000122 IDA involved_in negative regulation of transcription by RNA polymerase II 10851137,21259317 Process
15205 GO:0000122 IGI acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II 19050759 Process
15205 GO:0000122 IMP acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II 15870295 Process
15205 GO:0000122 IMP involved_in negative regulation of transcription by RNA polymerase II 19609448,20122914 Process
15205 GO:0001701 IGI acts_upstream_of_or_within in utero embryonic development 11500373 Process
15205 GO:0001709 IMP acts_upstream_of cell fate determination 11425898 Process
15205 GO:0001889 IMP acts_upstream_of_or_within liver development 15578515 Process
15205 GO:0002085 IMP acts_upstream_of_or_within inhibition of neuroepithelial cell differentiation 10952889 Process
15205 GO:0003143 IMP involved_in embryonic heart tube morphogenesis 19609448 Process
15205 GO:0003151 IMP acts_upstream_of_or_within outflow tract morphogenesis 19609448 Process
15205 GO:0003151 IMP involved_in outflow tract morphogenesis 20122914 Process
15205 GO:0003266 IMP acts_upstream_of_or_within regulation of secondary heart field cardioblast proliferation 19609448 Process
15205 GO:0003281 IMP involved_in ventricular septum development 20122914 Process
15205 GO:0003310 IMP acts_upstream_of pancreatic A cell differentiation 10615124 Process
15205 GO:0006357 IGI acts_upstream_of_or_within regulation of transcription by RNA polymerase II 20628571 Process
15205 GO:0007155 IGI acts_upstream_of_or_within cell adhesion 15496443 Process
15205 GO:0007219 IDA acts_upstream_of_or_within Notch signaling pathway 25535395 Process
15205 GO:0007224 IDA acts_upstream_of_or_within smoothened signaling pathway 19124651 Process
15205 GO:0007389 IGI acts_upstream_of_or_within pattern specification process 18302773 Process
15205 GO:0007389 IMP acts_upstream_of_or_within pattern specification process 18302773 Process
15205 GO:0008283 IMP acts_upstream_of cell population proliferation 16038893,17426285 Process
15205 GO:0008284 IMP acts_upstream_of_or_within positive regulation of cell population proliferation 16038893,17426285 Process
15205 GO:0008284 IMP involved_in positive regulation of cell population proliferation 20122914 Process
15205 GO:0016477 IGI acts_upstream_of_or_within cell migration 18996108 Process
15205 GO:0021537 IGI acts_upstream_of_or_within telencephalon development 18579678 Process
15205 GO:0021537 IMP acts_upstream_of_or_within telencephalon development 19050759 Process
15205 GO:0021555 IGI acts_upstream_of_or_within midbrain-hindbrain boundary morphogenesis 11500373 Process
15205 GO:0021557 IGI acts_upstream_of_or_within oculomotor nerve development 11500373 Process
15205 GO:0021558 IGI acts_upstream_of_or_within trochlear nerve development 11500373 Process
15205 GO:0021575 IGI acts_upstream_of_or_within hindbrain morphogenesis 11500373 Process
15205 GO:0021870 IGI acts_upstream_of Cajal-Retzius cell differentiation 18579678 Process
15205 GO:0021915 IGI acts_upstream_of_or_within neural tube development 10804175,11500373 Process
15205 GO:0021983 IGI acts_upstream_of_or_within pituitary gland development 17426285 Process
15205 GO:0021983 IMP acts_upstream_of_or_within pituitary gland development 17015435,17426285 Process
15205 GO:0021984 IMP acts_upstream_of_or_within adenohypophysis development 18996108 Process
15205 GO:0030182 IGI acts_upstream_of neuron differentiation 10205173,15496443 Process
15205 GO:0030182 IMP acts_upstream_of neuron differentiation 10205173,16038893 Process
15205 GO:0030324 IMP acts_upstream_of_or_within lung development 10952889 Process
15205 GO:0030509 IGI acts_upstream_of BMP signaling pathway 18579678 Process
15205 GO:0030513 IGI acts_upstream_of_or_within positive regulation of BMP signaling pathway 18579678 Process
15205 GO:0030901 IGI acts_upstream_of_or_within midbrain development 11500373 Process
15205 GO:0031016 IMP acts_upstream_of_or_within pancreas development 19619492 Process
15205 GO:0035019 IMP acts_upstream_of_or_within somatic stem cell population maintenance 10615124 Process
15205 GO:0035881 IMP acts_upstream_of amacrine cell differentiation 16038893 Process
15205 GO:0035909 IMP involved_in aorta morphogenesis 20122914 Process
15205 GO:0035910 IMP involved_in ascending aorta morphogenesis 19609448 Process
15205 GO:0042098 IMP acts_upstream_of T cell proliferation 15870295 Process
15205 GO:0042102 IMP acts_upstream_of_or_within positive regulation of T cell proliferation 15870295 Process
15205 GO:0042491 IGI acts_upstream_of inner ear auditory receptor cell differentiation 21300049 Process
15205 GO:0042531 IDA involved_in positive regulation of tyrosine phosphorylation of STAT protein 15156153 Process
15205 GO:0043388 IDA involved_in positive regulation of DNA binding 15156153 Process
15205 GO:0043433 IDA involved_in negative regulation of DNA-binding transcription factor activity 10851137 Process
15205 GO:0045165 IMP acts_upstream_of_or_within cell fate commitment 10952889 Process
15205 GO:0045596 IMP acts_upstream_of_or_within negative regulation of cell differentiation 17426285 Process
15205 GO:0045598 IMP acts_upstream_of_or_within regulation of fat cell differentiation 15060169 Process
15205 GO:0045608 IGI acts_upstream_of_or_within negative regulation of inner ear auditory receptor cell differentiation 21300049 Process
15205 GO:0045608 IMP acts_upstream_of_or_within negative regulation of inner ear auditory receptor cell differentiation 11023859,11425898 Process
15205 GO:0045664 IGI acts_upstream_of_or_within regulation of neuron differentiation 10804175 Process
15205 GO:0045665 IGI acts_upstream_of_or_within negative regulation of neuron differentiation 10205173,15496443,18579678 Process
15205 GO:0045665 IMP acts_upstream_of_or_within negative regulation of neuron differentiation 10205173,10952889,16038893 Process
15205 GO:0045747 IMP involved_in positive regulation of Notch signaling pathway 12208538 Process
15205 GO:0045892 IMP involved_in negative regulation of DNA-templated transcription 12208538 Process
15205 GO:0045893 IMP involved_in positive regulation of DNA-templated transcription 12208538 Process
15205 GO:0045944 IGI acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II 11500373,19050759 Process
15205 GO:0045944 IMP involved_in positive regulation of transcription by RNA polymerase II 19609448,20122914 Process
15205 GO:0045977 IMP involved_in positive regulation of mitotic cell cycle, embryonic 19609448 Process
15205 GO:0046331 IMP acts_upstream_of_or_within lateral inhibition 10804175 Process
15205 GO:0046425 IDA involved_in regulation of receptor signaling pathway via JAK-STAT 15156153 Process
15205 GO:0046427 IDA involved_in positive regulation of receptor signaling pathway via JAK-STAT 15156153 Process
15205 GO:0048469 IGI acts_upstream_of_or_within cell maturation 15496443 Process
15205 GO:0048505 IMP acts_upstream_of_or_within regulation of timing of cell differentiation 8543157,17015435 Process
15205 GO:0048538 IMP involved_in thymus development 20122914 Process
15205 GO:0048667 IGI acts_upstream_of_or_within cell morphogenesis involved in neuron differentiation 11500373 Process
15205 GO:0048711 IDA involved_in positive regulation of astrocyte differentiation 12666205 Process
15205 GO:0048715 IDA involved_in negative regulation of oligodendrocyte differentiation 12666205 Process
15205 GO:0048844 IMP involved_in artery morphogenesis 20122914 Process
15205 GO:0050678 IGI acts_upstream_of_or_within regulation of epithelial cell proliferation 21300049 Process
15205 GO:0050767 IGI acts_upstream_of_or_within regulation of neurogenesis 10804175,19050759 Process
15205 GO:0060122 IGI acts_upstream_of_or_within inner ear receptor cell stereocilium organization 21300049 Process
15205 GO:0060164 IGI acts_upstream_of_or_within regulation of timing of neuron differentiation 11500373 Process
15205 GO:0060164 IMP acts_upstream_of_or_within regulation of timing of neuron differentiation 8543157 Process
15205 GO:0060253 IDA involved_in negative regulation of glial cell proliferation 12666205 Process
15205 GO:0060412 IMP involved_in ventricular septum morphogenesis 19609448 Process
15205 GO:0060675 IEP involved_in ureteric bud morphogenesis 15821257 Process
15205 GO:0060716 IMP involved_in labyrinthine layer blood vessel development 20122914 Process
15205 GO:0061009 IMP acts_upstream_of_or_within common bile duct development 19619492 Process
15205 GO:0061101 IMP acts_upstream_of neuroendocrine cell differentiation 10952889 Process
15205 GO:0061102 IMP acts_upstream_of stomach neuroendocrine cell differentiation 18173746 Process
15205 GO:0061106 IMP acts_upstream_of_or_within negative regulation of stomach neuroendocrine cell differentiation 18173746 Process
15205 GO:0061309 IMP acts_upstream_of_or_within cardiac neural crest cell development involved in outflow tract morphogenesis 19609448 Process
15205 GO:0061626 IMP involved_in pharyngeal arch artery morphogenesis 20122914 Process
15205 GO:0065003 IDA involved_in protein-containing complex assembly 15156153 Process
15205 GO:0072012 IEP involved_in glomerulus vasculature development 15821257 Process
15205 GO:0072049 IEP involved_in comma-shaped body morphogenesis 15821257 Process
15205 GO:0072050 IEP involved_in S-shaped body morphogenesis 15821257 Process
15205 GO:0072141 IEP involved_in renal interstitial fibroblast development 15821257 Process
15205 GO:0072282 IEP involved_in metanephric nephron tubule morphogenesis 15465493 Process
15205 GO:0090102 IGI acts_upstream_of_or_within cochlea development 18302773 Process
15205 GO:0090102 IMP acts_upstream_of_or_within cochlea development 18302773 Process
15205 GO:0090162 IGI acts_upstream_of_or_within establishment of epithelial cell polarity 21300049 Process
15205 GO:0097084 IMP involved_in vascular associated smooth muscle cell development 20122914 Process
15205 GO:0097150 IMP involved_in neuronal stem cell population maintenance 11399758 Process
15205 GO:1902870 IMP acts_upstream_of_or_within negative regulation of amacrine cell differentiation 16038893 Process
15205 GO:1905934 IMP acts_upstream_of_or_within negative regulation of cell fate determination 11425898 Process
15205 GO:2000227 IMP acts_upstream_of_or_within negative regulation of pancreatic A cell differentiation 10615124 Process
15205 GO:2000981 IMP involved_in negative regulation of inner ear receptor cell differentiation 12208538 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
15205 GO:0000981 IDA enables DNA-binding transcription factor activity, RNA polymerase II-specific 15870295 Function
15205 GO:0001217 IDA enables DNA-binding transcription repressor activity 17681138 Function
15205 GO:0001227 IDA enables DNA-binding transcription repressor activity, RNA polymerase II-specific 21259317 Function
15205 GO:0003677 IDA enables DNA binding 10851137,14764602 Function
15205 GO:0005515 IPI enables protein binding 15156153,17681138,21259317 Function
15205 GO:0042803 IDA enables protein homodimerization activity 21259317 Function
15205 GO:0043398 IDA enables HLH domain binding 17681138 Function
15205 GO:0051087 IDA enables protein-folding chaperone binding 16314515 Function
15205 GO:0061629 IPI enables RNA polymerase II-specific DNA-binding transcription factor binding 10851137 Function
15205 GO:0070888 IDA enables E-box binding 10851137 Function
15205 GO:0071820 IDA enables N-box binding 10851137,17681138 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
15205 GO:0005622 IDA located_in intracellular anatomical structure 16489008 Component
15205 GO:0005634 IDA located_in nucleus 10952889,12666205,15156153,15645444,17079689,23284756..... Component
15205 GO:0005737 IDA located_in cytoplasm 15645444 Component
15205 GO:0032991 IDA part_of protein-containing complex 17681138 Component