Gene Ontology

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 15258
  • Symbol: Hipk2
  • Description: homeodomain interacting protein kinase 2

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
15258 GO:0000122 IDA involved_in negative regulation of transcription by RNA polymerase II 9748262 Process
15258 GO:0001934 IGI acts_upstream_of_or_within positive regulation of protein phosphorylation 20360400 Process
15258 GO:0003016 IGI acts_upstream_of_or_within respiratory system process 31582725 Process
15258 GO:0006468 IDA involved_in protein phosphorylation 9748262 Process
15258 GO:0006468 IGI acts_upstream_of protein phosphorylation 20360400 Process
15258 GO:0007179 IMP acts_upstream_of_or_within transforming growth factor beta receptor signaling pathway 17159989 Process
15258 GO:0007224 IGI acts_upstream_of_or_within smoothened signaling pathway 16537918 Process
15258 GO:0007628 IMP acts_upstream_of_or_within adult walking behavior 17159989 Process
15258 GO:0008283 IGI acts_upstream_of cell population proliferation 16537918 Process
15258 GO:0008284 IGI acts_upstream_of_or_within positive regulation of cell population proliferation 16537918 Process
15258 GO:0008344 IMP acts_upstream_of_or_within adult locomotory behavior 17159989 Process
15258 GO:0009952 IGI acts_upstream_of_or_within anterior/posterior pattern specification 16537918 Process
15258 GO:0010467 IGI acts_upstream_of_or_within gene expression 31582725 Process
15258 GO:0010842 IMP involved_in retina layer formation 20579985 Process
15258 GO:0018105 IDA involved_in peptidyl-serine phosphorylation 16407227 Process
15258 GO:0018107 IDA involved_in peptidyl-threonine phosphorylation 16407227 Process
15258 GO:0030182 IMP involved_in neuron differentiation 20579985 Process
15258 GO:0030878 IGI acts_upstream_of_or_within thyroid gland development 31582725 Process
15258 GO:0032092 IDA involved_in positive regulation of protein binding 16407227 Process
15258 GO:0042771 IGI acts_upstream_of_or_within intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 16537918 Process
15258 GO:0043388 IDA involved_in positive regulation of DNA binding 9748262 Process
15258 GO:0043524 IMP acts_upstream_of_or_within negative regulation of neuron apoptotic process 17159989 Process
15258 GO:0045944 IGI acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II 17159989 Process
15258 GO:0045944 IMP involved_in positive regulation of transcription by RNA polymerase II 16407227 Process
15258 GO:0048596 IMP involved_in embryonic camera-type eye morphogenesis 20579985 Process
15258 GO:0050882 IMP acts_upstream_of_or_within voluntary musculoskeletal movement 17159989 Process
15258 GO:0051091 IDA involved_in positive regulation of DNA-binding transcription factor activity 16407227 Process
15258 GO:0051402 IMP acts_upstream_of neuron apoptotic process 17159989 Process
15258 GO:0060059 IMP involved_in embryonic retina morphogenesis in camera-type eye 20579985 Process
15258 GO:0060235 IMP involved_in lens induction in camera-type eye 20579985 Process
15258 GO:0060425 IGI acts_upstream_of_or_within lung morphogenesis 31582725 Process
15258 GO:0061072 IMP involved_in iris morphogenesis 20579985 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
15258 GO:0003677 IDA NOT enables DNA binding 9748262 Function
15258 GO:0003713 IMP contributes_to transcription coactivator activity 16407227 Function
15258 GO:0003714 IDA enables transcription corepressor activity 9748262 Function
15258 GO:0004672 IDA enables protein kinase activity 9748262 Function
15258 GO:0004674 IDA enables protein serine/threonine kinase activity 16407227 Function
15258 GO:0005515 IPI enables protein binding 9748262,15082531,15492043,15526030,18093972,19820693,20360400,..... Function
15258 GO:0061629 IPI enables RNA polymerase II-specific DNA-binding transcription factor binding 16407227 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
15258 GO:0005634 IDA located_in nucleus 9748262,20579985 Component
15258 GO:0005737 IDA located_in cytoplasm 11078605 Component
15258 GO:0032991 IDA part_of protein-containing complex 16870469 Component
15258 GO:0090575 IMP part_of RNA polymerase II transcription regulator complex 16407227 Component