Gene Ontology

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 15357
  • Symbol: Hmgcr
  • Description: 3-hydroxy-3-methylglutaryl-Coenzyme A reductase

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
15357 GO:0004420 IDA enables hydroxymethylglutaryl-CoA reductase (NADPH) activity 1352323,7798939,8647961,9186920,11792727,12114517,12920113,158..... Function
15357 GO:0030695 IGI enables GTPase regulator activity 16271875 Function

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
15357 GO:0006695 IDA acts_upstream_of_or_within cholesterol biosynthetic process 7798939,8647961,15845870 Process
15357 GO:0008542 IGI acts_upstream_of_or_within visual learning 16271875 Process
15357 GO:0009790 IMP acts_upstream_of_or_within embryo development 12920113 Process
15357 GO:0042177 IMP involved_in negative regulation of protein catabolic process 20876579 Process
15357 GO:0043407 IGI acts_upstream_of_or_within negative regulation of MAP kinase activity 12409258,16271875 Process
15357 GO:0050709 IMP involved_in negative regulation of protein secretion 20876579 Process
15357 GO:0060291 IGI acts_upstream_of_or_within long-term synaptic potentiation 16271875 Process
15357 GO:0070372 IGI acts_upstream_of_or_within regulation of ERK1 and ERK2 cascade 16271875 Process
15357 GO:1900222 IMP involved_in negative regulation of amyloid-beta clearance 20876579 Process