Gene Ontology

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 16334
  • Symbol: Ins2
  • Description: insulin II

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
16334 GO:0000122 IDA acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II 9689059 Process
16334 GO:0006006 IMP acts_upstream_of_or_within glucose metabolic process 11854325 Process
16334 GO:0006983 IMP acts_upstream_of_or_within ER overload response 11854325 Process
16334 GO:0007520 IGI acts_upstream_of_or_within myoblast fusion 15282335 Process
16334 GO:0008286 IDA acts_upstream_of_or_within insulin receptor signaling pathway 12805218 Process
16334 GO:0008286 IMP involved_in insulin receptor signaling pathway 20056832 Process
16334 GO:0010468 IDA acts_upstream_of_or_within regulation of gene expression 19293336 Process
16334 GO:0014902 IGI acts_upstream_of_or_within myotube differentiation 15282335 Process
16334 GO:0016042 IDA acts_upstream_of_or_within lipid catabolic process 12805218 Process
16334 GO:0030070 IGI involved_in insulin processing 20424817 Process
16334 GO:0031623 IDA acts_upstream_of_positive_effect receptor internalization 17264162 Process
16334 GO:0042325 IDA acts_upstream_of_or_within regulation of phosphorylation 12059784 Process
16334 GO:0042593 IMP acts_upstream_of_or_within glucose homeostasis 23274896 Process
16334 GO:0043393 IDA acts_upstream_of_or_within regulation of protein binding 9507006 Process
16334 GO:0043552 IDA acts_upstream_of_or_within positive regulation of phosphatidylinositol 3-kinase activity 11375348 Process
16334 GO:0050731 IDA acts_upstream_of_or_within positive regulation of peptidyl-tyrosine phosphorylation 23775122 Process
16334 GO:0061903 IDA acts_upstream_of_or_within positive regulation of 1-phosphatidylinositol-3-kinase activity 11375348 Process
16334 GO:0070059 IMP acts_upstream_of_or_within intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress 11854325 Process
16334 GO:0070374 IDA acts_upstream_of_or_within positive regulation of ERK1 and ERK2 cascade 12059784 Process

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
16334 GO:0005615 IDA is_active_in extracellular space 9452465,27055260 Component
16334 GO:0005634 IDA located_in nucleus 12488434 Component
16334 GO:0005732 IDA part_of sno(s)RNA-containing ribonucleoprotein complex 12488434 Component
16334 GO:0005737 IDA located_in cytoplasm 15793245 Component
16334 GO:0005829 IDA located_in cytosol 21828338 Component
16334 GO:0030141 IDA located_in secretory granule 15788565 Component
16334 GO:0062023 HDA located_in collagen-containing extracellular matrix 28071719 Component

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
16334 GO:0008270 IGI enables zinc ion binding 20424817 Function