Gene Ontology

Gene Info

• Species: Worm (Caenorhabditis elegans)
• GeneID: 172458
• Symbol: hlh-2
• Description: Helix-loop-helix protein hlh-2

Process

Export (tab separated) Export to Excel

GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
172458	GO:0000003	IMP	involved_in	reproduction	14660442	Process
172458	GO:0001708	IMP	involved_in	cell fate specification	11076762,14701877,15282161,19376107	Process
172458	GO:0002119	IMP	involved_in	nematode larval development	14627726	Process
172458	GO:0006357	IDA	involved_in	regulation of transcription by RNA polymerase II	19632181	Process
172458	GO:0008340	IMP	acts_upstream_of_or_within_positive_effect	determination of adult lifespan	32203922	Process
172458	GO:0008406	IMP	involved_in	gonad development	14660442,15282161	Process
172458	GO:0009792	IMP	involved_in	embryo development ending in birth or egg hatching	14627726	Process
172458	GO:0010171	IMP	involved_in	body morphogenesis	14627726	Process
172458	GO:0010628	IMP	involved_in	positive regulation of gene expression	19376107,21784067,25982859,31402303,32203922	Process
172458	GO:0014018	IGI	involved_in	neuroblast fate specification	14627726	Process
172458	GO:0014018	IMP	involved_in	neuroblast fate specification	14627726	Process
172458	GO:0030718	IMP	involved_in	germ-line stem cell population maintenance	19376107	Process
172458	GO:0032094	IMP	involved_in	response to food	27487365	Process
172458	GO:0034769	IMP	involved_in	basement membrane disassembly	21784067	Process
172458	GO:0035262	IMP	involved_in	gonad morphogenesis	15282161,19376107,25982859	Process
172458	GO:0040025	IMP	involved_in	vulval development	14660442,21784067	Process
172458	GO:0042743	IMP	involved_in	hydrogen peroxide metabolic process	32203922	Process
172458	GO:0043068	IGI	involved_in	positive regulation of programmed cell death	12874127	Process
172458	GO:0043068	IMP	involved_in	positive regulation of programmed cell death	12874127	Process
172458	GO:0045138	IGI	involved_in	nematode male tail tip morphogenesis	11076762	Process
172458	GO:0045138	IMP	involved_in	nematode male tail tip morphogenesis	11076762	Process
172458	GO:0045944	IGI	involved_in	positive regulation of transcription by RNA polymerase II	9716413,11799068,16480708	Process
172458	GO:0045944	IMP	involved_in	positive regulation of transcription by RNA polymerase II	14660442,14701877,27487365	Process
172458	GO:0046034	IMP	involved_in	ATP metabolic process	32203922	Process
172458	GO:0048665	IMP	involved_in	neuron fate specification	29301976	Process
172458	GO:0048666	IGI	involved_in	neuron development	11076762	Process
172458	GO:1903356	IMP	involved_in	positive regulation of distal tip cell migration	25982859	Process
172458	GO:1990636	IMP	acts_upstream_of_or_within_negative_effect	reproductive senescence	32203922	Process
172458	GO:2000114	IMP	involved_in	regulation of establishment of cell polarity	21784067	Process

Function

Export (tab separated) Export to Excel

GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
172458	GO:0000977	IDA	contributes_to	RNA polymerase II transcription regulatory region sequence-specific DNA binding	9187144	Function
172458	GO:0000977	IDA	enables	RNA polymerase II transcription regulatory region sequence-specific DNA binding	9187144	Function
172458	GO:0000978	IMP	enables	RNA polymerase II cis-regulatory region sequence-specific DNA binding	27487365	Function
172458	GO:0000981	IDA	enables	DNA-binding transcription factor activity, RNA polymerase II-specific	19632181	Function
172458	GO:0000981	IPI	enables	DNA-binding transcription factor activity, RNA polymerase II-specific	19632181	Function
172458	GO:0005515	IPI	enables	protein binding	19632181	Function
172458	GO:0042803	IPI	enables	protein homodimerization activity	9187144,9716413,11076762	Function
172458	GO:0043425	IPI	enables	bHLH transcription factor binding	19632181	Function
172458	GO:0043565	IDA	enables	sequence-specific DNA binding	9716413,11076762,12874127,14660442,17215301	Function
172458	GO:0046982	IPI	enables	protein heterodimerization activity	9187144,9716413,11076762	Function

Component

Export (tab separated) Export to Excel

GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
172458	GO:0005634	IDA	located_in	nucleus	9187144,11076762,12874127,15282161	Component
172458	GO:0005737	IDA	located_in	cytoplasm	15282161	Component
172458	GO:0090575	IDA	part_of	RNA polymerase II transcription regulator complex	9187144	Component
172458	GO:0090575	IPI	part_of	RNA polymerase II transcription regulator complex	19632181	Component