Gene Ontology

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 17257
  • Symbol: Mecp2
  • Description: methyl CpG binding protein 2

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
17257 GO:0000122 IDA acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II 10888872 Process
17257 GO:0000122 IMP acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II 15608638 Process
17257 GO:0001662 IMP acts_upstream_of_or_within behavioral fear response 16199017,16467389 Process
17257 GO:0001666 IMP acts_upstream_of_or_within response to hypoxia 17997046 Process
17257 GO:0001964 IMP acts_upstream_of_or_within startle response 18321864 Process
17257 GO:0001976 IMP acts_upstream_of_or_within nervous system process involved in regulation of systemic arterial blood pressure 17544925 Process
17257 GO:0002087 IMP acts_upstream_of_or_within regulation of respiratory gaseous exchange by nervous system process 16354910,18321864 Process
17257 GO:0006020 IMP acts_upstream_of_or_within inositol metabolic process 17237885 Process
17257 GO:0006349 IMP acts_upstream_of_or_within regulation of gene expression by genomic imprinting 15608638 Process
17257 GO:0006357 IMP acts_upstream_of_or_within regulation of transcription by RNA polymerase II 16467389 Process
17257 GO:0006541 IMP acts_upstream_of_or_within glutamine metabolic process 17237885 Process
17257 GO:0006576 IMP acts_upstream_of_or_within biogenic amine metabolic process 15975715 Process
17257 GO:0007219 IDA involved_in Notch signaling pathway 30560934 Process
17257 GO:0007268 IMP acts_upstream_of_or_within chemical synaptic transmission 16399702 Process
17257 GO:0007416 IMP acts_upstream_of_or_within synapse assembly 17920015,18295506 Process
17257 GO:0007420 IMP acts_upstream_of_or_within brain development 18571096 Process
17257 GO:0007585 IMP acts_upstream_of_or_within respiratory gaseous exchange by respiratory system 11242117 Process
17257 GO:0007612 IMP acts_upstream_of_or_within learning 16467389,18321864 Process
17257 GO:0007613 IMP acts_upstream_of_or_within memory 16399702 Process
17257 GO:0007616 IMP acts_upstream_of_or_within long-term memory 16399702 Process
17257 GO:0008104 IMP acts_upstream_of_or_within protein localization 17296936 Process
17257 GO:0008211 IMP acts_upstream_of_or_within glucocorticoid metabolic process 17108082 Process
17257 GO:0008283 IMP acts_upstream_of cell population proliferation 15939091 Process
17257 GO:0008306 IMP involved_in associative learning 26158416 Process
17257 GO:0008344 IMP acts_upstream_of_or_within adult locomotory behavior 11242117,16467389 Process
17257 GO:0008542 IMP acts_upstream_of_or_within visual learning 16399702 Process
17257 GO:0009790 IMP acts_upstream_of_or_within embryo development 8563762 Process
17257 GO:0009791 IMP acts_upstream_of_or_within post-embryonic development 16467389 Process
17257 GO:0010467 IDA involved_in gene expression 30560934 Process
17257 GO:0010467 IMP involved_in gene expression 30560934 Process
17257 GO:0010468 IDA acts_upstream_of_or_within regulation of gene expression 18203756 Process
17257 GO:0014009 IMP acts_upstream_of glial cell proliferation 15939091 Process
17257 GO:0016358 IMP acts_upstream_of_or_within dendrite development 15519245,17532643 Process
17257 GO:0016571 IMP acts_upstream_of_or_within histone methylation 15757975 Process
17257 GO:0016573 IMP acts_upstream_of_or_within histone acetylation 15757975 Process
17257 GO:0019230 IMP acts_upstream_of_or_within proprioception 16467389,18321864 Process
17257 GO:0019233 IMP acts_upstream_of_or_within sensory perception of pain 18321864 Process
17257 GO:0021549 IMP acts_upstream_of_or_within cerebellum development 18571096 Process
17257 GO:0021591 IMP acts_upstream_of_or_within ventricular system development 18571096 Process
17257 GO:0030182 IDA involved_in neuron differentiation 30560934 Process
17257 GO:0030182 IMP acts_upstream_of_or_within neuron differentiation 15345242 Process
17257 GO:0030182 IMP involved_in neuron differentiation 30560934 Process
17257 GO:0031175 IMP acts_upstream_of_or_within neuron projection development 15345242 Process
17257 GO:0031507 IMP acts_upstream_of_or_within heterochromatin formation 15608638 Process
17257 GO:0032048 IMP acts_upstream_of_or_within cardiolipin metabolic process 17237885 Process
17257 GO:0033555 IMP acts_upstream_of_or_within multicellular organismal response to stress 17108082 Process
17257 GO:0035176 IMP acts_upstream_of_or_within social behavior 16199017,18321864 Process
17257 GO:0040029 IMP acts_upstream_of_or_within epigenetic regulation of gene expression 15757975,17532643 Process
17257 GO:0042551 IMP acts_upstream_of_or_within neuron maturation 15519245,17532643,18295506 Process
17257 GO:0043524 IMP acts_upstream_of_or_within negative regulation of neuron apoptotic process 17997046 Process
17257 GO:0045892 IDA acts_upstream_of_or_within negative regulation of DNA-templated transcription 18511691 Process
17257 GO:0045892 IMP acts_upstream_of_or_within negative regulation of DNA-templated transcription 17108082 Process
17257 GO:0045893 IDA acts_upstream_of_or_within positive regulation of DNA-templated transcription 18511691 Process
17257 GO:0045944 IMP acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II 16782889,17050729 Process
17257 GO:0046470 IMP acts_upstream_of_or_within phosphatidylcholine metabolic process 17237885 Process
17257 GO:0048167 IMP acts_upstream_of_or_within regulation of synaptic plasticity 16399702 Process
17257 GO:0050432 IMP acts_upstream_of catecholamine secretion 17050729 Process
17257 GO:0050884 IMP acts_upstream_of_or_within neuromuscular process controlling posture 11242117 Process
17257 GO:0050905 IMP acts_upstream_of_or_within neuromuscular process 16199017,16467389 Process
17257 GO:0051151 IMP involved_in negative regulation of smooth muscle cell differentiation 25722434 Process
17257 GO:0051570 IMP acts_upstream_of_or_within regulation of histone H3-K9 methylation 15608638 Process
17257 GO:0051707 IMP acts_upstream_of_or_within response to other organism 17997046 Process
17257 GO:0060079 IMP acts_upstream_of_or_within excitatory postsynaptic potential 17920015 Process
17257 GO:0060252 IMP acts_upstream_of_or_within positive regulation of glial cell proliferation 15939091 Process
17257 GO:0060291 IMP acts_upstream_of_or_within long-term synaptic potentiation 16087343 Process
17257 GO:0099191 IMP acts_upstream_of trans-synaptic signaling by BDNF 17050729 Process
17257 GO:1900114 IDA involved_in positive regulation of histone H3-K9 trimethylation 25722434 Process
17257 GO:2000820 IDA involved_in negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation 25722434 Process

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
17257 GO:0000792 IDA part_of heterochromatin 14519686,17296936 Component
17257 GO:0005634 IDA located_in nucleus 11809720,14593184,15939091,16199017,17546630,17997046,18511691..... Component
17257 GO:0005737 IDA located_in cytoplasm 17546630 Component
17257 GO:0005829 IDA located_in cytosol 15939091 Component

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
17257 GO:0003677 IDA enables DNA binding 18511691 Function
17257 GO:0003682 IDA enables chromatin binding 15608638 Function
17257 GO:0003700 IDA enables DNA-binding transcription factor activity 18511691 Function
17257 GO:0003700 IMP enables DNA-binding transcription factor activity 17108082 Function
17257 GO:0003714 IDA enables transcription corepressor activity 25722434 Function
17257 GO:0003729 IDA enables mRNA binding 15342650 Function
17257 GO:0005515 IPI enables protein binding 15696166,17296936,18511691,19602036,20159591,20385708,20599664..... Function
17257 GO:0008134 IPI enables transcription factor binding 14593184 Function
17257 GO:0008327 IDA enables methyl-CpG binding 15342650,17108082 Function
17257 GO:0010385 IDA enables double-stranded methylated DNA binding 14593184,15757975 Function
17257 GO:0035197 IDA enables siRNA binding 15342650 Function
17257 GO:1990841 IDA enables promoter-specific chromatin binding 16782889 Function