Gene Ontology

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 17260
  • Symbol: Mef2c
  • Description: myocyte enhancer factor 2C

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
17260 GO:0000122 IGI acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II 7677753 Process
17260 GO:0000165 IDA involved_in MAPK cascade 14515274 Process
17260 GO:0000165 IMP involved_in MAPK cascade 18955699 Process
17260 GO:0001568 IMP acts_upstream_of_or_within blood vessel development 9778514,17336904 Process
17260 GO:0001649 IEP involved_in osteoblast differentiation 21652706 Process
17260 GO:0001649 IGI acts_upstream_of_or_within osteoblast differentiation 17336904 Process
17260 GO:0001764 IMP involved_in neuron migration 18599437 Process
17260 GO:0001782 IMP involved_in B cell homeostasis 19211936 Process
17260 GO:0001947 IMP involved_in heart looping 16680724 Process
17260 GO:0001958 IGI acts_upstream_of_or_within endochondral ossification 17336904 Process
17260 GO:0001958 IMP acts_upstream_of_or_within endochondral ossification 17336904 Process
17260 GO:0001974 IMP acts_upstream_of_or_within blood vessel remodeling 9162005,10395786 Process
17260 GO:0002062 IGI acts_upstream_of_or_within chondrocyte differentiation 17336904 Process
17260 GO:0002467 IMP involved_in germinal center formation 18955699 Process
17260 GO:0002634 IMP involved_in regulation of germinal center formation 18438409 Process
17260 GO:0003138 IMP involved_in primary heart field specification 16680724 Process
17260 GO:0003139 IMP involved_in secondary heart field specification 15890826 Process
17260 GO:0003151 IGI acts_upstream_of_or_within outflow tract morphogenesis 19035347 Process
17260 GO:0003185 IMP involved_in sinoatrial valve morphogenesis 16680724 Process
17260 GO:0003211 IGI acts_upstream_of_or_within cardiac ventricle formation 19035347 Process
17260 GO:0003211 IMP involved_in cardiac ventricle formation 16680724 Process
17260 GO:0006355 IDA acts_upstream_of_or_within regulation of DNA-templated transcription 12130539 Process
17260 GO:0006959 IMP involved_in humoral immune response 18955699 Process
17260 GO:0007507 IMP acts_upstream_of_or_within heart development 9778514,10395786 Process
17260 GO:0007519 IMP acts_upstream_of_or_within skeletal muscle tissue development 17786239 Process
17260 GO:0007521 IMP acts_upstream_of_or_within muscle cell fate determination 17786239 Process
17260 GO:0007611 IMP involved_in learning or memory 18599437,18599438 Process
17260 GO:0010467 IMP involved_in gene expression 30735130 Process
17260 GO:0010628 IDA involved_in positive regulation of gene expression 18579729 Process
17260 GO:0010628 IMP involved_in positive regulation of gene expression 16680724,21652706 Process
17260 GO:0010629 IMP involved_in negative regulation of gene expression 16680724 Process
17260 GO:0010694 IMP involved_in positive regulation of alkaline phosphatase activity 21652706 Process
17260 GO:0014033 IMP involved_in neural crest cell differentiation 21610032 Process
17260 GO:0014898 IMP acts_upstream_of_or_within cardiac muscle hypertrophy in response to stress 10531040 Process
17260 GO:0030182 IMP involved_in neuron differentiation 18599437 Process
17260 GO:0030220 IMP involved_in platelet formation 19211936 Process
17260 GO:0030224 IMP acts_upstream_of_or_within monocyte differentiation 18326819 Process
17260 GO:0030318 IMP involved_in melanocyte differentiation 21610032 Process
17260 GO:0030501 IMP involved_in positive regulation of bone mineralization 21652706 Process
17260 GO:0030890 IMP involved_in positive regulation of B cell proliferation 18955699 Process
17260 GO:0035050 IGI involved_in embryonic heart tube development 30735130 Process
17260 GO:0035050 IMP involved_in embryonic heart tube development 30735130 Process
17260 GO:0035914 IMP acts_upstream_of_or_within skeletal muscle cell differentiation 22147266 Process
17260 GO:0035984 IDA involved_in cellular response to trichostatin A 20181743 Process
17260 GO:0042100 IMP involved_in B cell proliferation 18438409 Process
17260 GO:0043523 IMP involved_in regulation of neuron apoptotic process 22496871 Process
17260 GO:0043524 IDA involved_in negative regulation of neuron apoptotic process 18579729 Process
17260 GO:0045165 IMP acts_upstream_of_or_within cell fate commitment 19169261 Process
17260 GO:0045652 IMP involved_in regulation of megakaryocyte differentiation 19211936 Process
17260 GO:0045666 IDA involved_in positive regulation of neuron differentiation 18579729 Process
17260 GO:0045669 IMP involved_in positive regulation of osteoblast differentiation 21652706 Process
17260 GO:0045893 IDA acts_upstream_of_or_within positive regulation of DNA-templated transcription 9738004 Process
17260 GO:0045893 IDA involved_in positive regulation of DNA-templated transcription 11554755,14515274,21610032 Process
17260 GO:0045893 IMP acts_upstream_of_or_within positive regulation of DNA-templated transcription 9162005 Process
17260 GO:0045944 IDA acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II 16818234,17336904,17352741,18086704 Process
17260 GO:0045944 IDA involved_in positive regulation of transcription by RNA polymerase II 7760790,8668199 Process
17260 GO:0045944 IGI acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II 8900141,15743821,17336904,17420000,18093911,20399744..... Process
17260 GO:0045944 IMP involved_in positive regulation of transcription by RNA polymerase II 15890826,20181743 Process
17260 GO:0046928 IMP involved_in regulation of neurotransmitter secretion 18599438 Process
17260 GO:0048167 IMP involved_in regulation of synaptic plasticity 22496871 Process
17260 GO:0048666 IMP involved_in neuron development 18599437 Process
17260 GO:0048667 IMP involved_in cell morphogenesis involved in neuron differentiation 18599437 Process
17260 GO:0048703 IMP acts_upstream_of_or_within embryonic viscerocranium morphogenesis 17420000 Process
17260 GO:0048704 IMP acts_upstream_of_or_within embryonic skeletal system morphogenesis 17420000 Process
17260 GO:0050680 IMP involved_in negative regulation of epithelial cell proliferation 20181743 Process
17260 GO:0050853 IMP involved_in B cell receptor signaling pathway 18955699 Process
17260 GO:0051145 IMP acts_upstream_of_or_within smooth muscle cell differentiation 9778514 Process
17260 GO:0051963 IMP involved_in regulation of synapse assembly 18599438 Process
17260 GO:0051966 IMP involved_in regulation of synaptic transmission, glutamatergic 18599438 Process
17260 GO:0055007 IGI acts_upstream_of_or_within cardiac muscle cell differentiation 19035347,20691899 Process
17260 GO:0055012 IMP involved_in ventricular cardiac muscle cell differentiation 16680724 Process
17260 GO:0060021 IGI acts_upstream_of_or_within roof of mouth development 17420000 Process
17260 GO:0060025 IMP involved_in regulation of synaptic activity 18599437,18599438,22496871 Process
17260 GO:0060045 IMP involved_in positive regulation of cardiac muscle cell proliferation 16680724 Process
17260 GO:0060079 IMP involved_in excitatory postsynaptic potential 18599437,18599438 Process
17260 GO:0060297 IMP acts_upstream_of_or_within regulation of sarcomere organization 17875930 Process
17260 GO:0060536 IMP acts_upstream_of_or_within cartilage morphogenesis 17420000 Process
17260 GO:0060998 IMP involved_in regulation of dendritic spine development 18599438 Process
17260 GO:0061333 IMP involved_in renal tubule morphogenesis 20181743 Process
17260 GO:0071222 IDA involved_in cellular response to lipopolysaccharide 18955699 Process
17260 GO:0071277 IDA involved_in cellular response to calcium ion 15998798 Process
17260 GO:0071466 IDA involved_in cellular response to xenobiotic stimulus 16775627 Process
17260 GO:0071498 IDA involved_in cellular response to fluid shear stress 20181743 Process
17260 GO:0071838 IGI acts_upstream_of cell proliferation in bone marrow 18278031 Process
17260 GO:0071864 IGI acts_upstream_of_or_within positive regulation of cell proliferation in bone marrow 18278031 Process
17260 GO:0072102 IMP involved_in glomerulus morphogenesis 20181743 Process
17260 GO:0072160 IMP involved_in nephron tubule epithelial cell differentiation 20181743 Process
17260 GO:0097492 IMP involved_in sympathetic neuron axon guidance 30735130 Process
17260 GO:1902287 IMP involved_in semaphorin-plexin signaling pathway involved in axon guidance 30735130 Process
17260 GO:2000111 IMP involved_in positive regulation of macrophage apoptotic process 16775627 Process
17260 GO:2000310 IMP involved_in regulation of NMDA receptor activity 18599438 Process
17260 GO:2000311 IMP involved_in regulation of AMPA receptor activity 18599438 Process
17260 GO:2000727 IMP involved_in positive regulation of cardiac muscle cell differentiation 16680724 Process
17260 GO:2000987 IMP involved_in positive regulation of behavioral fear response 18579729 Process
17260 GO:2001013 IMP involved_in epithelial cell proliferation involved in renal tubule morphogenesis 20181743 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
17260 GO:0000976 IDA enables transcription cis-regulatory region binding 8035824 Function
17260 GO:0000977 IDA enables RNA polymerase II transcription regulatory region sequence-specific DNA binding 15890826 Function
17260 GO:0000978 IDA enables RNA polymerase II cis-regulatory region sequence-specific DNA binding 7760790,8668199,19477969,20181743 Function
17260 GO:0000981 IDA enables DNA-binding transcription factor activity, RNA polymerase II-specific 17420000,18093911,21610032 Function
17260 GO:0000987 IDA enables cis-regulatory region sequence-specific DNA binding 16140986,20399744 Function
17260 GO:0001228 IDA enables DNA-binding transcription activator activity, RNA polymerase II-specific 7760790,8506376,8668199,17875930 Function
17260 GO:0001228 IMP enables DNA-binding transcription activator activity, RNA polymerase II-specific 20181743 Function
17260 GO:0003677 IDA enables DNA binding 14762206 Function
17260 GO:0003682 IDA enables chromatin binding 18086704 Function
17260 GO:0003700 IDA enables DNA-binding transcription factor activity 12130539 Function
17260 GO:0005515 IPI enables protein binding 12130539,14515274,15102471,16818234,18955699,19753306,23565059..... Function
17260 GO:0042826 IPI enables histone deacetylase binding 10983972 Function
17260 GO:0043565 IDA enables sequence-specific DNA binding 17336904,21556048,21610032 Function
17260 GO:0071837 IPI enables HMG box domain binding 11554755,21610032 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
17260 GO:0005634 IDA located_in nucleus 11081517,11554755,15998798,18086704,19796622,20181743,21610032..... Component