Gene Ontology

Gene Info

  • Species: Worm (Caenorhabditis elegans)
  • GeneID: 172981
  • Symbol: daf-16
  • Description: Forkhead box protein O

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
172981 GO:0000122 IGI involved_in negative regulation of transcription by RNA polymerase II 26963674 Process
172981 GO:0000122 IMP involved_in negative regulation of transcription by RNA polymerase II 23770237,25330323,26963674 Process
172981 GO:0002119 IMP involved_in nematode larval development 11747821 Process
172981 GO:0002821 IMP involved_in positive regulation of adaptive immune response 17096597,18245330 Process
172981 GO:0006355 IDA involved_in regulation of DNA-templated transcription 17096597,17894411 Process
172981 GO:0006974 IDA involved_in DNA damage response 22922647 Process
172981 GO:0006979 IGI involved_in response to oxidative stress 21531333 Process
172981 GO:0007614 IGI involved_in short-term memory 26675724 Process
172981 GO:0008286 IDA involved_in insulin receptor signaling pathway 11124266 Process
172981 GO:0008286 IMP involved_in insulin receptor signaling pathway 24834345 Process
172981 GO:0008340 IDA involved_in determination of adult lifespan 19103192,22922647 Process
172981 GO:0008340 IGI involved_in determination of adult lifespan 11381260,17277769,20523893,23352664,27001890 Process
172981 GO:0008340 IMP involved_in determination of adult lifespan 11381260,11747821,15905404,17277769,22560223,23352664,23665919..... Process
172981 GO:0008582 IGI involved_in regulation of synaptic assembly at neuromuscular junction 23665919 Process
172981 GO:0009411 IDA involved_in response to UV 11747825 Process
172981 GO:0009411 IGI involved_in response to UV 21531333 Process
172981 GO:0010286 IGI involved_in heat acclimation 21531333 Process
172981 GO:0010468 IMP involved_in regulation of gene expression 32963007 Process
172981 GO:0010564 IEP involved_in regulation of cell cycle process 17934462 Process
172981 GO:0010628 IMP involved_in positive regulation of gene expression 17526726,21531333 Process
172981 GO:0010883 IGI involved_in regulation of lipid storage 21531333 Process
172981 GO:0030431 IGI involved_in sleep 29523076 Process
172981 GO:0032436 IMP involved_in positive regulation of proteasomal ubiquitin-dependent protein catabolic process 23770237 Process
172981 GO:0034599 IGI involved_in cellular response to oxidative stress 15905404 Process
172981 GO:0034605 IDA involved_in cellular response to heat 11381260,11747825 Process
172981 GO:0040015 IMP involved_in negative regulation of multicellular organism growth 12571101 Process
172981 GO:0040024 IGI involved_in dauer larval development 11381260,15905404 Process
172981 GO:0042594 IMP involved_in response to starvation 23352664 Process
172981 GO:0043065 IMP involved_in positive regulation of apoptotic process 17934462 Process
172981 GO:0043620 IMP involved_in regulation of DNA-templated transcription in response to stress 12750521 Process
172981 GO:0045087 IMP involved_in innate immune response 19454349 Process
172981 GO:0045887 IGI involved_in positive regulation of synaptic assembly at neuromuscular junction 23665919 Process
172981 GO:0045944 IDA involved_in positive regulation of transcription by RNA polymerase II 11124266 Process
172981 GO:0045944 IMP involved_in positive regulation of transcription by RNA polymerase II 15905404,19454349 Process
172981 GO:0046890 IMP involved_in regulation of lipid biosynthetic process 18762027 Process
172981 GO:0050829 IGI involved_in defense response to Gram-negative bacterium 16916933 Process
172981 GO:0050829 IMP involved_in defense response to Gram-negative bacterium 19454349 Process
172981 GO:0050830 IMP involved_in defense response to Gram-positive bacterium 24972867 Process
172981 GO:0060537 IMP involved_in muscle tissue development 18397876 Process
172981 GO:0061065 IGI involved_in regulation of dauer larval development 1732156,21124868 Process
172981 GO:0061066 IMP involved_in positive regulation of dauer larval development 6583682 Process
172981 GO:1900075 IGI involved_in positive regulation of neuromuscular synaptic transmission 23665919 Process
172981 GO:1900426 IMP involved_in positive regulation of defense response to bacterium 22554143 Process
172981 GO:1905909 IGI involved_in regulation of dauer entry 21531333,24671950 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
172981 GO:0000977 IDA enables RNA polymerase II transcription regulatory region sequence-specific DNA binding 19506556 Function
172981 GO:0000978 IDA enables RNA polymerase II cis-regulatory region sequence-specific DNA binding 26963674 Function
172981 GO:0000981 IMP enables DNA-binding transcription factor activity, RNA polymerase II-specific 26963674 Function
172981 GO:0003700 IDA enables DNA-binding transcription factor activity 11124266,22922647 Function
172981 GO:0005515 IPI enables protein binding 11124266,15068796,16777605,16860373,18358814,23255046..... Function
172981 GO:0008013 IPI enables beta-catenin binding 15905404 Function
172981 GO:0017151 IPI enables DEAD/H-box RNA helicase binding 26195740 Function
172981 GO:0019899 IPI enables enzyme binding 23028355 Function
172981 GO:0031625 IPI enables ubiquitin protein ligase binding 17276341 Function
172981 GO:0043565 IDA enables sequence-specific DNA binding 11124266 Function
172981 GO:0071889 IPI enables 14-3-3 protein binding 17098225,21531333 Function
172981 GO:0140297 IPI enables DNA-binding transcription factor binding 19103192 Function
172981 GO:1990381 IPI enables ubiquitin-specific protease binding 26154057 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
172981 GO:0005634 IDA located_in nucleus 11124266,11381260,11747821,19252938,19454349,21531333,22922647..... Component
172981 GO:0005737 IDA located_in cytoplasm 11124266,11381260,11747821,19454349,21531333,23665919,23911329..... Component
172981 GO:0005829 IDA located_in cytosol 22922647 Component