Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 1739
  • Symbol: DLG1
  • Description: discs large MAGUK scaffold protein 1

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
1739 GO:0000122 IMP involved_in negative regulation of transcription by RNA polymerase II 20551903 Process
1739 GO:0001935 IDA involved_in endothelial cell proliferation 14699157 Process
1739 GO:0007015 IDA involved_in actin filament organization 14699157 Process
1739 GO:0008360 IMP involved_in regulation of cell shape 20551903 Process
1739 GO:0030866 IDA involved_in cortical actin cytoskeleton organization 14699157 Process
1739 GO:0030953 IMP involved_in astral microtubule organization 20551903 Process
1739 GO:0031503 IMP involved_in protein-containing complex localization 20551903 Process
1739 GO:0042391 IDA involved_in regulation of membrane potential 12970345 Process
1739 GO:0043268 IDA involved_in positive regulation of potassium ion transport 12970345 Process
1739 GO:0043622 IMP involved_in cortical microtubule organization 20551903 Process
1739 GO:0051660 IMP involved_in establishment of centrosome localization 20551903 Process
1739 GO:0070373 IMP involved_in negative regulation of ERK1 and ERK2 cascade 20551903 Process
1739 GO:0070830 IDA involved_in bicellular tight junction assembly 17332497 Process
1739 GO:0072659 IMP involved_in protein localization to plasma membrane 17332497 Process
1739 GO:0098609 IDA involved_in cell-cell adhesion 14699157 Process
1739 GO:1901222 IMP NOT involved_in regulation of NIK/NF-kappaB signaling 20551903 Process
1739 GO:1902473 IDA involved_in regulation of protein localization to synapse 23676497 Process
1739 GO:1903078 IDA involved_in positive regulation of protein localization to plasma membrane 12970345 Process
1739 GO:1903753 IMP involved_in negative regulation of p38MAPK cascade 20551903 Process
1739 GO:2000134 IMP involved_in negative regulation of G1/S transition of mitotic cell cycle 10656683 Process

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
1739 GO:0001772 IDA located_in immunological synapse 20551903 Component
1739 GO:0005634 IDA located_in nucleus 17237226 Component
1739 GO:0005737 IDA located_in cytoplasm 17237226,21615688 Component
1739 GO:0005783 IDA located_in endoplasmic reticulum 21615688 Component
1739 GO:0005794 IDA located_in Golgi apparatus 21615688 Component
1739 GO:0005874 IDA located_in microtubule 21615688 Component
1739 GO:0005911 IDA located_in cell-cell junction 21615688 Component
1739 GO:0005923 IDA located_in bicellular tight junction 17332497 Component
1739 GO:0009898 IDA located_in cytoplasmic side of plasma membrane 21615688 Component
1739 GO:0016323 IDA located_in basolateral plasma membrane 8922391 Component
1739 GO:0030054 IDA located_in cell junction 12857860,17237226 Component
1739 GO:0048471 IDA located_in perinuclear region of cytoplasm 21615688 Component
1739 GO:0070062 HDA located_in extracellular exosome 20458337 Component
1739 GO:0097025 IDA part_of MPP7-DLG1-LIN7 complex 17237226 Component
1739 GO:0097060 IDA located_in synaptic membrane 23676497 Component

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
1739 GO:0005515 IPI enables protein binding 8638125,8922391,9192623,9341123,10779557,10859302,11274188,116..... Function
1739 GO:0015459 IDA enables potassium channel regulator activity 12970345 Function
1739 GO:0019902 IPI enables phosphatase binding 10646847 Function
1739 GO:0044325 IPI enables transmembrane transporter binding 12970345 Function
1739 GO:0045296 HDA enables cadherin binding 25468996 Function
1739 GO:0097016 IPI enables L27 domain binding 17332497 Function