Gene Ontology

Gene Info

• Species: Mouse (Mus musculus)
• GeneID: 18016
• Symbol: Nf2
• Description: neurofibromin 2

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
18016	GO:0000165	IMP	acts_upstream_of	MAPK cascade	16405865	Process
18016	GO:0001707	IMP	acts_upstream_of_or_within	mesoderm formation	9171370	Process
18016	GO:0006469	IDA	acts_upstream_of_or_within	negative regulation of protein kinase activity	14580336	Process
18016	GO:0006469	IMP	acts_upstream_of_or_within	negative regulation of protein kinase activity	16405865	Process
18016	GO:0007398	IMP	acts_upstream_of_or_within	ectoderm development	9171370	Process
18016	GO:0007420	IMP	acts_upstream_of_or_within	brain development	23863479	Process
18016	GO:0008285	IMP	acts_upstream_of_or_within	negative regulation of cell population proliferation	9553042	Process
18016	GO:0010626	IMP	acts_upstream_of_or_within	negative regulation of Schwann cell proliferation	10887156	Process
18016	GO:0014010	IMP	acts_upstream_of	Schwann cell proliferation	10887156	Process
18016	GO:0014013	IMP	acts_upstream_of_or_within	regulation of gliogenesis	25433207	Process
18016	GO:0021766	IMP	acts_upstream_of_or_within	hippocampus development	23863479	Process
18016	GO:0031647	IMP	acts_upstream_of_or_within	regulation of protein stability	23863479	Process
18016	GO:0033687	IMP	acts_upstream_of	osteoblast proliferation	10887156	Process
18016	GO:0033689	IMP	acts_upstream_of_or_within	negative regulation of osteoblast proliferation	10887156	Process
18016	GO:0042127	IMP	acts_upstream_of_or_within	regulation of cell population proliferation	12695331	Process
18016	GO:0042475	IMP	acts_upstream_of_or_within	odontogenesis of dentin-containing tooth	10887156	Process
18016	GO:0043409	IMP	acts_upstream_of_or_within	negative regulation of MAPK cascade	16405865	Process
18016	GO:0045216	IMP	acts_upstream_of_or_within	cell-cell junction organization	12695331	Process
18016	GO:0045597	IMP	acts_upstream_of_or_within	positive regulation of cell differentiation	23863479	Process
18016	GO:0050767	IMP	acts_upstream_of_or_within	regulation of neurogenesis	25433207	Process
18016	GO:0070306	IMP	involved_in	lens fiber cell differentiation	20181838	Process
18016	GO:0072091	IGI	acts_upstream_of_or_within	regulation of stem cell proliferation	25433207	Process
18016	GO:0072091	IMP	acts_upstream_of_or_within	regulation of stem cell proliferation	25433207	Process
18016	GO:1900180	IMP	acts_upstream_of_or_within	regulation of protein localization to nucleus	23863479	Process
18016	GO:2000177	IMP	acts_upstream_of_or_within	regulation of neural precursor cell proliferation	23863479	Process

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
18016	GO:0001726	IDA	located_in	ruffle	9563848	Component
18016	GO:0005634	IDA	located_in	nucleus	15133494	Component
18016	GO:0005737	IDA	located_in	cytoplasm	8547603,15133494	Component
18016	GO:0005856	IDA	located_in	cytoskeleton	15467741	Component
18016	GO:0005912	IMP	located_in	adherens junction	12695331	Component
18016	GO:0030027	IDA	located_in	lamellipodium	9563848	Component
18016	GO:0030175	IDA	located_in	filopodium	9563848	Component
18016	GO:0030864	IDA	located_in	cortical actin cytoskeleton	15467741	Component
18016	GO:0032154	IDA	located_in	cleavage furrow	9631655	Component
18016	GO:0043005	IDA	located_in	neuron projection	25433207	Component
18016	GO:0044297	IDA	located_in	cell body	25433207	Component
18016	GO:0045177	IDA	located_in	apical part of cell	23863479	Component

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
18016	GO:0005515	IPI	enables	protein binding	12695331,14580336,16405865,25026211	Function