Gene Ontology

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 18018
  • Symbol: Nfatc1
  • Description: nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
18018 GO:0000082 IMP acts_upstream_of_or_within G1/S transition of mitotic cell cycle 12660151 Process
18018 GO:0000122 IDA acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II 19463978 Process
18018 GO:0000122 IGI acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II 19463978 Process
18018 GO:0000122 IMP acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II 18243104 Process
18018 GO:0001837 IMP acts_upstream_of_or_within epithelial to mesenchymal transition 15339668 Process
18018 GO:0001946 IGI acts_upstream_of_or_within lymphangiogenesis 19233265 Process
18018 GO:0002337 IMP acts_upstream_of_or_within B-1a B cell differentiation 14595020 Process
18018 GO:0003170 IMP involved_in heart valve development 22300732 Process
18018 GO:0003176 IMP involved_in aortic valve development 22300732 Process
18018 GO:0003177 IMP involved_in pulmonary valve development 22300732 Process
18018 GO:0003179 IMP acts_upstream_of_or_within heart valve morphogenesis 9515963 Process
18018 GO:0003180 IMP acts_upstream_of_or_within aortic valve morphogenesis 9515964 Process
18018 GO:0003184 IMP acts_upstream_of_or_within pulmonary valve morphogenesis 9515964 Process
18018 GO:0003197 IGI involved_in endocardial cushion development 22300732 Process
18018 GO:0006357 IMP involved_in regulation of transcription by RNA polymerase II 22019888 Process
18018 GO:0006366 IDA acts_upstream_of transcription by RNA polymerase II 19233265,19463978 Process
18018 GO:0006366 IGI acts_upstream_of transcription by RNA polymerase II 19463978 Process
18018 GO:0006366 IMP acts_upstream_of transcription by RNA polymerase II 18243104 Process
18018 GO:0006816 IMP acts_upstream_of_or_within calcium ion transport 12660151 Process
18018 GO:0007507 IMP acts_upstream_of_or_within heart development 15339668 Process
18018 GO:0010467 IMP acts_upstream_of_or_within gene expression 23259949 Process
18018 GO:0010628 IDA acts_upstream_of_or_within positive regulation of gene expression 22451653 Process
18018 GO:0010839 IMP acts_upstream_of_or_within negative regulation of keratinocyte proliferation 18243104 Process
18018 GO:0014883 IMP acts_upstream_of_or_within transition between fast and slow fiber 18408153 Process
18018 GO:0030316 IGI acts_upstream_of_or_within osteoclast differentiation 21982707 Process
18018 GO:0033173 IMP acts_upstream_of_or_within calcineurin-NFAT signaling cascade 19233265 Process
18018 GO:0042634 IMP acts_upstream_of_or_within regulation of hair cycle 18243104 Process
18018 GO:0043616 IMP acts_upstream_of keratinocyte proliferation 18243104 Process
18018 GO:0044838 IMP acts_upstream_of_or_within cell quiescence 18243104 Process
18018 GO:0045668 IDA acts_upstream_of_or_within negative regulation of osteoblast differentiation 19463978 Process
18018 GO:0045944 IDA acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II 12808150,17430895,17442941,19233265 Process
18018 GO:0045944 IDA involved_in positive regulation of transcription by RNA polymerase II 15304486 Process
18018 GO:0060412 IMP acts_upstream_of_or_within ventricular septum morphogenesis 9515964 Process
18018 GO:0060854 IMP acts_upstream_of_or_within branching involved in lymph vessel morphogenesis 19233265 Process
18018 GO:0061384 IMP acts_upstream_of_or_within heart trabecula morphogenesis 9515963 Process
18018 GO:0071277 IDA acts_upstream_of_or_within cellular response to calcium ion 23259949 Process
18018 GO:0072089 IMP acts_upstream_of stem cell proliferation 18243104 Process
18018 GO:1905314 IMP involved_in semi-lunar valve development 22300732 Process
18018 GO:2000647 IMP acts_upstream_of_or_within negative regulation of stem cell proliferation 18243104 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
18018 GO:0000978 IDA enables RNA polymerase II cis-regulatory region sequence-specific DNA binding 15304486,18625840 Function
18018 GO:0000981 IDA enables DNA-binding transcription factor activity, RNA polymerase II-specific 15304486 Function
18018 GO:0001227 IDA enables DNA-binding transcription repressor activity, RNA polymerase II-specific 18408153 Function
18018 GO:0001228 IDA enables DNA-binding transcription activator activity, RNA polymerase II-specific 15304486 Function
18018 GO:0003677 IDA enables DNA binding 23980096 Function
18018 GO:0003682 IDA enables chromatin binding 24301466 Function
18018 GO:0005515 IPI enables protein binding 15380363,19463978,21880741,23990468 Function
18018 GO:0043565 IDA enables sequence-specific DNA binding 7650004,15058383 Function
18018 GO:0048273 IPI enables mitogen-activated protein kinase p38 binding 15304486 Function
18018 GO:0061629 IPI enables RNA polymerase II-specific DNA-binding transcription factor binding 15304486 Function
18018 GO:0140297 IPI enables DNA-binding transcription factor binding 11889139 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
18018 GO:0005634 IDA is_active_in nucleus 23259949 Component
18018 GO:0005634 IDA located_in nucleus 9515963,9515964,10903175,11782539,12970181,15304486,15850572,1..... Component
18018 GO:0005667 IPI part_of transcription regulator complex 19561615 Component
18018 GO:0005737 IDA is_active_in cytoplasm 23259949 Component
18018 GO:0005737 IDA located_in cytoplasm 10903175,12091710,12469121,15304486,19463978,19626032,21982707..... Component