Gene Ontology

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 18145
  • Symbol: Npc1
  • Description: NPC intracellular cholesterol transporter 1

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
18145 GO:0001889 IMP acts_upstream_of_or_within liver development 21289032 Process
18145 GO:0006486 IDA involved_in protein glycosylation 22065762 Process
18145 GO:0006897 IMP acts_upstream_of_or_within endocytosis 15078881 Process
18145 GO:0007628 IGI acts_upstream_of_or_within adult walking behavior 19074461 Process
18145 GO:0009410 IDA acts_upstream_of_or_within response to xenobiotic stimulus 10787428 Process
18145 GO:0010467 IMP acts_upstream_of_or_within gene expression 21289032 Process
18145 GO:0010467 IMP involved_in gene expression 29463856 Process
18145 GO:0010878 IMP acts_upstream_of_or_within cholesterol storage 21697390 Process
18145 GO:0012501 IMP acts_upstream_of_or_within programmed cell death 21697390 Process
18145 GO:0015918 IMP acts_upstream_of_or_within sterol transport 21289032 Process
18145 GO:0016125 IMP acts_upstream_of_or_within sterol metabolic process 21289032,21697390 Process
18145 GO:0016236 IGI acts_upstream_of macroautophagy 17468177 Process
18145 GO:0016236 IMP acts_upstream_of macroautophagy 17468177 Process
18145 GO:0016242 IGI acts_upstream_of_or_within negative regulation of macroautophagy 17468177 Process
18145 GO:0016242 IMP acts_upstream_of_or_within negative regulation of macroautophagy 17468177 Process
18145 GO:0022008 IMP acts_upstream_of_or_within neurogenesis 21697390 Process
18145 GO:0030301 IMP acts_upstream_of_or_within cholesterol transport 21697390 Process
18145 GO:0033344 IMP acts_upstream_of_or_within cholesterol efflux 17148552 Process
18145 GO:0042632 IMP involved_in cholesterol homeostasis 21896731 Process
18145 GO:0046718 IMP involved_in viral entry into host cell 21866101,21866103 Process
18145 GO:0051649 IMP acts_upstream_of_or_within establishment of localization in cell 17148552 Process
18145 GO:0071383 IDA acts_upstream_of_or_within cellular response to steroid hormone stimulus 10787428 Process
18145 GO:0071404 IDA acts_upstream_of_or_within cellular response to low-density lipoprotein particle stimulus 10787428 Process
18145 GO:2000900 IMP acts_upstream_of_or_within cyclodextrin metabolic process 21697390 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
18145 GO:0005515 IPI enables protein binding 16757520,22065762,34237247 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
18145 GO:0005576 IDA located_in extracellular region 22065762 Component
18145 GO:0005635 IDA located_in nuclear envelope 20457914 Component
18145 GO:0005764 IDA is_active_in lysosome 21289032 Component
18145 GO:0005764 IDA located_in lysosome 10787428,21896731,22065762 Component
18145 GO:0005768 IDA located_in endosome 10787428,16757520 Component
18145 GO:0005794 IDA located_in Golgi apparatus 10787428 Component
18145 GO:0005886 IDA located_in plasma membrane 10787428 Component
18145 GO:0016020 IDA located_in membrane 10787428 Component
18145 GO:0031982 IDA located_in vesicle 10787428 Component
18145 GO:0045121 IDA located_in membrane raft 10787428 Component