Gene Ontology

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 182
• Symbol: JAG1
• Description: jagged canonical Notch ligand 1

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
182	GO:0001953	IDA	involved_in	negative regulation of cell-matrix adhesion	11549580	Process
182	GO:0002456	IMP	involved_in	T cell mediated immunity	23086448	Process
182	GO:0003184	IMP	involved_in	pulmonary valve morphogenesis	9207787,20437614	Process
182	GO:0007219	IMP	involved_in	Notch signaling pathway	19682396	Process
182	GO:0022408	IDA	involved_in	negative regulation of cell-cell adhesion	11549580	Process
182	GO:0030336	IDA	involved_in	negative regulation of cell migration	11549580	Process
182	GO:0045944	IMP	involved_in	positive regulation of transcription by RNA polymerase II	20437614	Process
182	GO:0061156	IMP	involved_in	pulmonary artery morphogenesis	9207787	Process
182	GO:0061314	IMP	involved_in	Notch signaling involved in heart development	20437614	Process
182	GO:0097150	IEP	involved_in	neuronal stem cell population maintenance	19682396	Process
182	GO:2000737	IMP	involved_in	negative regulation of stem cell differentiation	19682396	Process

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
182	GO:0005112	IPI	enables	Notch binding	11006133	Function
182	GO:0005515	IPI	enables	protein binding	18660822,23086448	Function
182	GO:0005543	IMP	enables	phospholipid binding	22465068	Function
182	GO:0060090	EXP	enables	molecular adaptor activity	16427310	Function
182	GO:0060090	IDA	enables	molecular adaptor activity	16427310	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
182	GO:0005886	IDA	located_in	plasma membrane	20437614,32065591	Component
182	GO:0016020	IMP	colocalizes_with	membrane	22465068	Component