Gene Ontology

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 18412
  • Symbol: Sqstm1
  • Description: sequestosome 1

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
18412 GO:0000122 IMP acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II 24035364 Process
18412 GO:0001659 IMP involved_in temperature homeostasis 32385399 Process
18412 GO:0006366 IMP acts_upstream_of transcription by RNA polymerase II 24035364 Process
18412 GO:0006468 IMP involved_in protein phosphorylation 32385399 Process
18412 GO:0006606 IDA involved_in protein import into nucleus 32385399 Process
18412 GO:0006606 IMP involved_in protein import into nucleus 32385399 Process
18412 GO:0006914 IDA involved_in autophagy 20173742,20421418 Process
18412 GO:0031397 IDA involved_in negative regulation of protein ubiquitination 20173742,20421418 Process
18412 GO:0070342 IMP involved_in brown fat cell proliferation 32385399 Process
18412 GO:0097009 IMP involved_in energy homeostasis 32385399 Process
18412 GO:1900273 IMP involved_in positive regulation of long-term synaptic potentiation 19004011 Process
18412 GO:1903078 IMP involved_in positive regulation of protein localization to plasma membrane 19004011 Process

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
18412 GO:0000407 IDA located_in phagophore assembly site 21220506 Component
18412 GO:0005739 IDA located_in mitochondrion 32047033 Component
18412 GO:0005776 IDA located_in autophagosome 24713655 Component
18412 GO:0016235 IDA located_in aggresome 22792322 Component
18412 GO:0044754 IDA located_in autolysosome 26284655 Component
18412 GO:0097225 IDA located_in sperm midpiece 22033522 Component

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
18412 GO:0005515 IPI enables protein binding 15102471,16252010,17389358,18083104,19250911,20173742,20421418..... Function
18412 GO:0035255 IPI enables ionotropic glutamate receptor binding 19004011 Function
18412 GO:0042802 IDA enables identical protein binding 21220506 Function
18412 GO:0070530 IDA enables K63-linked polyubiquitin modification-dependent protein binding 16252010 Function